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Joe Hin Tjio

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with the wrong liquid led Tjio and Levan to develop better techniques for staining and counting chromosomes. It allowed researchers for the first time to see and count each chromosome clearly in the HeLa cells with which they were working. They were the first to show that humans have 23 pairs of
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After the war ended, Tjio went to the Netherlands, whose government provided him with a fellowship for study in Europe. He worked in plant breeding in Denmark, Spain and Sweden. From 1948 to 1959 he did plant chromosome research in
384:. He spent the balance of his career at the NIH in human chromosome research. He was named scientist emeritus in 1992, but maintained a laboratory for the next five years. In 1997, he retired to 290:; 2 November 1919 – 27 November 2001), was an Indonesian-born American cytogeneticist. He was renowned as the first person to recognize the normal number of human 582: 359:, that involve the number of chromosomes. Tjio made his discovery of the correct human chromosome count (46 chromosomes, rather than 48 as counted in 1921 by 587: 523: 592: 602: 423: 489: 464: 355:
chromosomes rather than 24, as was previously believed. This was important for the study of developmental disorders, such as
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and later known as Indonesia. His father was a photographer. Tjio was educated in Dutch colonial schools, trained in
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in college, and did research on potato breeding. He was imprisoned for 3 years and tortured by the Japanese in a
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In 1958 Tjio went to the United States and in 1959 he joined the staff of the
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in Spain and spent his summers in Sweden working with Professor
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Tjio was born to Indonesian parents of Chinese origin in
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on 22 December 1955 at the Institute of Genetics of the
435:(in Chinese (Taiwan)), pp. 86–91, archived from 208: 273: 524:"5 Contributions HeLa Cells Have Made to Science" 559: 298:in Sweden, where he was a visiting scientist. 583:American people of Chinese-Indonesian descent 178: 164: 31: 588:Indonesian emigrants to the United States 521: 481: 350:In 1953, a lab mistake involving mixing 487: 560: 528:Cell Science from Technology Networks 462: 458: 456: 593:Indonesian people of Chinese descent 463:Saxon, Wolfgang (7 December 2001), 421: 404:Hereditas vol. 42: pages 1–6, 1956. 13: 603:American people of Chinese descent 488:McManus, Rich (11 February 1997), 453: 14: 619: 545: 16:Indonesian geneticist (1919–2001) 522:MacDonald, Anna (13 June 2018). 269: 113:Joseph P. Kennedy Jr. Foundation 388:where he died in 2001 aged 82. 247: 233: 554:in MedTerms Medical Dictionary 515: 415: 209: 179: 165: 87:Bogor Institute of Agriculture 1: 408: 374:National Institutes of Health 301: 111:International Prize Award by 400:The chromosome number of man 137:National Institute of Health 7: 10: 624: 333: 258: 240: 223: 216: 202: 195: 190: 186: 172: 158: 154: 149: 141: 133: 125: 118: 107: 99: 95:Inga Bjorg Arna Bildsfell 91: 83: 64: 39: 30: 23: 432: 424: 391: 160:Traditional Chinese 174:Simplified Chinese 598:People from Pekalongan 552:Human chromosome count 386:Gaithersburg, Maryland 382:University of Colorado 578:American geneticists 369:on 26 January 1956. 500:(3), archived from 314:, then part of the 469:The New York Times 397:Tjio JH, Levan A. 378:Bethesda, Maryland 361:Theophilus Painter 324:concentration camp 296:University of Lund 422:李名揚 (July 2008), 316:Dutch East Indies 262: 261: 254: 253: 197:Standard Mandarin 145: 144: 120:Scientific career 58:Dutch East Indies 615: 608:Hakka scientists 539: 538: 536: 534: 519: 513: 512: 511: 509: 485: 479: 478: 477: 475: 460: 451: 450: 449: 447: 442:on 28 March 2012 441: 430: 419: 289: 288: 285: 284: 281: 278: 275: 250: 249: 236: 235: 212: 211: 188: 187: 182: 181: 168: 167: 147: 146: 71: 68:27 November 2001 49: 47: 35: 21: 20: 623: 622: 618: 617: 616: 614: 613: 612: 558: 557: 548: 543: 542: 532: 530: 520: 516: 507: 505: 504:on 21 July 2011 486: 482: 473: 471: 461: 454: 445: 443: 439: 434: 428: 426: 420: 416: 411: 394: 336: 304: 272: 268: 84:Alma mater 79: 78:, Maryland, U.S 73: 69: 60: 51: 50:2 November 1919 45: 43: 26: 17: 12: 11: 5: 621: 611: 610: 605: 600: 595: 590: 585: 580: 575: 570: 556: 555: 547: 546:External links 544: 541: 540: 514: 494:The NIH Record 480: 452: 413: 412: 410: 407: 406: 405: 393: 390: 335: 332: 303: 300: 260: 259: 256: 255: 252: 251: 248:Tsiúnn Iú-hing 244: 238: 237: 230: 221: 220: 214: 213: 206: 200: 199: 193: 192: 191:Transcriptions 184: 183: 176: 170: 169: 162: 156: 155: 152: 151: 143: 142: 139: 138: 135: 131: 130: 127: 123: 122: 116: 115: 109: 105: 104: 101: 97: 96: 93: 89: 88: 85: 81: 80: 74: 72:(aged 82) 66: 62: 61: 52: 41: 37: 36: 28: 27: 24: 15: 9: 6: 4: 3: 2: 620: 609: 606: 604: 601: 599: 596: 594: 591: 589: 586: 584: 581: 579: 576: 574: 571: 569: 566: 565: 563: 553: 550: 549: 529: 525: 518: 503: 499: 495: 491: 484: 470: 466: 459: 457: 438: 427: 418: 414: 403: 401: 396: 395: 389: 387: 383: 379: 375: 370: 368: 367: 362: 358: 357:Down syndrome 353: 348: 346: 342: 331: 329: 325: 321: 317: 313: 309: 299: 297: 293: 287: 266: 257: 245: 243: 239: 234:Chiúⁿ Iú-hing 231: 229: 226: 222: 219: 215: 210:Jiǎng Yǒuxìng 207: 205: 201: 198: 194: 189: 185: 177: 175: 171: 163: 161: 157: 153: 148: 140: 136: 132: 128: 124: 121: 117: 114: 110: 106: 102: 98: 94: 90: 86: 82: 77: 67: 63: 59: 55: 42: 38: 34: 29: 22: 19: 531:. Retrieved 527: 517: 506:, retrieved 502:the original 497: 493: 483: 472:, retrieved 468: 444:, retrieved 437:the original 417: 398: 371: 364: 349: 345:Albert Levan 337: 328:World War II 305: 265:Joe Hin Tjio 264: 263: 218:Southern Min 204:Hanyu Pinyin 150:Joe Hin Tjio 134:Institutions 129:Cytogenetics 119: 76:Gaithersburg 70:(2001-11-27) 25:Joe Hin Tjio 18: 573:2001 deaths 568:1919 births 292:chromosomes 562:Categories 409:References 352:HeLa cells 308:Pekalongan 302:Early life 54:Pekalongan 46:1919-11-02 366:Hereditas 347:in Lund. 533:25 March 508:3 August 474:3 August 446:3 August 425:台灣癌症醫療之母 341:Zaragoza 320:agronomy 100:Children 326:during 225:Hokkien 334:Career 242:Tâi-lô 126:Fields 108:Awards 92:Spouse 440:(PDF) 429:(PDF) 392:Works 103:1 son 535:2020 510:2011 476:2011 448:2011 433:科學人看 312:Java 65:Died 40:Born 431:, 376:in 228:POJ 180:蒋有兴 166:蔣有興 564:: 526:. 498:46 496:, 492:, 467:, 455:^ 330:. 310:, 283:oʊ 280:iː 277:tʃ 56:, 537:. 402:. 286:/ 274:ˈ 271:/ 267:( 48:) 44:(

Index


Pekalongan
Dutch East Indies
Gaithersburg
Joseph P. Kennedy Jr. Foundation
Traditional Chinese
Simplified Chinese
Standard Mandarin
Hanyu Pinyin
Southern Min
Hokkien
POJ
Tâi-lô
/ˈ/
chromosomes
University of Lund
Pekalongan
Java
Dutch East Indies
agronomy
concentration camp
World War II
Zaragoza
Albert Levan
HeLa cells
Down syndrome
Theophilus Painter
Hereditas
National Institutes of Health
Bethesda, Maryland

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