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Infarction

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558: 212: 720: 483: 43: 255: 1321: 764: 116: 1309: 268: 204:), ruptured by trauma causing a loss of blood pressure downstream of the rupture, or vasoconstricted, which is the narrowing of the blood vessel by contraction of the muscle wall rather than an external force (e.g., cocaine vasoconstriction leading to 234:. In atherosclerotic formations, a plaque develops under a fibrous cap. When the fibrous cap is degraded by metalloproteinases released from macrophages or by intravascular shear force from blood flow, subendothelial thrombogenic material ( 180:, which is the insufficient supply of oxygen and nutrition to an area of tissue due to a disruption in blood supply. The blood vessel supplying the affected area of tissue may be blocked due to an obstruction in the vessel (e.g., an 1016:
Sekido, Nobuaki; Mukaida, Naofumi; Harada, Akihisa; Nakanishi, Isao; Watanabe, Yoh; Matsushima, Kouji (1993). "Prevention of lung reperfusion injury in rabbits by a monoclonal antibody against interleukin-8".
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due to a disturbance in the blood vessels supplying blood to the brain. It can be atherothrombotic or embolic. Stroke caused by cerebral infarction should be distinguished from two other kinds of stroke:
992: 602:. Cerebral infarctions vary in their severity with one third of the cases resulting in death. In response to ischemia, the brain degenerates by the process of liquefactive necrosis. 879: 1390: 557: 1162: 905: 1068:
Sands, Howard; Tuma, Ronald F (1999). "LEX 032: a novel recombinant human protein for the treatment of ischaemic reperfusion injury".
641:, sometimes radiating to the left shoulder. Fever and chills develop in some cases. It has to be differentiated from other causes of 1280: 1383: 968:. CollinsDictionary.com. Collins English Dictionary – Complete & Unabridged 11th Edition. Retrieved November 22, 2012. 1138: 828: 515:, is an infarction of the heart, causing some heart cells to die. This is most commonly due to occlusion (blockage) of a 723:
Ultrasound of segmental testicular infarction. Infarct area shown as hypoechoic and avascular upper segment of R testis.
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Histopathology at high magnification of a normal brain neuron, and a brain infarction at approximately 24 hours on
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which travels with the blood-flow downstream to where the vessel narrows and eventually clogs the vessel lumen.
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Nores, M; Phillips, EH; Morgenstern, L; Hiatt, JR (1998). "The clinical spectrum of splenic infarction".
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Grigoriadis, E; Fam, AG; Starok, M; Ang, LC (2000). "Skeletal muscle infarction in diabetes mellitus".
1166: 1133:. Vinay Kumar, Abul K. Abbas, Jon C. Aster, James A. Perkins (Ninth ed.). Philadelphia, PA. 2015. 838: 694: 211: 1523: 1518: 1351: 774: 547:, if left untreated for a sufficient period of time, can cause damage or kill heart muscle tissue ( 126: 1427: 778: 599: 350: 130: 965: 732: 227: 189: 917: 1475: 943: 504: 445: 205: 719: 1026: 848: 235: 951:
The American Heritage Dictionary of the English Language, Fourth Edition. Updated in 2009.
8: 1480: 1465: 1437: 864: 746: 595: 582: 453: 364: 1030: 1485: 1262: 1156: 1050: 708: 686: 618: 437: 425: 416: 384: 334: 239: 238:) is exposed to circulating platelets and thrombus formation occurs on the vessel wall 53:
of a pulmonary infarct (right of image) beside relatively normal lung (left of image).
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Digiovanni, CW; Patel, A; Calfee, R; Nickisch, F (2007). "Osteonecrosis in the foot".
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A blood clot could be a broken thrombosis that got clotted to the blood vessel wall.
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Ropper, Allan H.; Adams, Raymond Delacy; Brown, Robert F.; Victor, Maurice (2005).
1077: 1054: 1034: 742: 528: 482: 473: 380: 346: 303: 283: 181: 91: 192:), compressed by something outside of the vessel causing it to narrow (e.g.,  1490: 1356: 652: 609: 516: 231: 223: 42: 254: 1460: 1422: 1081: 634: 622: 388: 360: 287: 1512: 1148: 979:"Infarct | Origin and meaning of infarct by Online Etymology Dictionary" 886: 642: 457: 1368: 1258: 1223: 1089: 939: 630: 569:. There is slight edema and loss of normal architecture in the surrounding 562: 219: 54: 1193: 1128: 1046: 954:
The American Heritage Science Dictionary 2005 by Houghton Mifflin Company.
712: 1320: 626: 566: 549: 532: 338: 87: 50: 24: 1343: 1399: 1038: 693:, it often leads to destruction of the joint articular surfaces (see 565:: The neurons become hypereosinophilic and there is an infiltrate of 465: 409: 327: 67: 20: 880:
first aid for myocardial infarction (due to acute coronary syndrome)
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Infarctions are divided into two types according to the amount of
1107:. New York: McGraw-Hill Medical Pub. Division. pp. 686–704. 461: 315: 299: 749:
due to blockages in the arteries or veins that supply the bowel.
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blood flow. Occasionally, the plaque may rupture and form an
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The Journal of the American Academy of Orthopaedic Surgeons
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as a rare complication of long standing, poorly controlled
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tissues previously congested from sluggish venous outflow
675:. A major presentation is painful thigh or leg swelling. 215:
Infarction could be caused by damaged cholesterol plaque
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first aid for stroke (using a protocol named F.A.S.T.).
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Diseases commonly associated with infarctions include:
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or one of its branches are occluded, for example by a
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which supplies the retina causing sudden visual loss.
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Micrograph of testis showing hemorrhagic infarction.
1333: 395:strands. Characteristics of red infarcts include: 258:Infarction of the lung due to a pulmonary embolism 993:"Infarction - an overview | ScienceDirect Topics" 1510: 875:Each type of infarction requires its own care. 1205: 1203: 1130:Robbins and Cotran pathologic basis of disease 306:substantially limits the amount of nutrients ( 1384: 98:is referred to as an infarct (from the Latin 1398: 715:(s) if not undone by surgery quickly enough. 1200: 1173: 792:. Unsourced material may be challenged and 176:Infarction occurs as a result of prolonged 144:. Unsourced material may be challenged and 16:Tissue death due to inadequate blood supply 1391: 1377: 1281:"Testicular torsion - Symptoms and causes" 1230: 1161:: CS1 maint: location missing publisher ( 1105:Adams and Victor's principles of neurology 86:to the affected area. It may be caused by 41: 1067: 812:Learn how and when to remove this message 164:Learn how and when to remove this message 718: 556: 481: 266: 253: 210: 1070:Expert Opinion on Investigational Drugs 1511: 753: 90:, rupture, mechanical compression, or 1372: 523:, which is an unstable collection of 790:adding citations to reliable sources 757: 262: 142:adding citations to reliable sources 109: 829:Peripheral artery occlusive disease 13: 831:(the most severe form of which is 639:left upper quadrant of the abdomen 543:(restriction in blood supply) and 494: 290:) affect solid organs such as the 14: 1535: 1301: 885:Infarction in the brain requires 878:Infarction in the heart requires 731:: an infarction can occur to the 521:vulnerable atherosclerotic plaque 249: 1319: 1307: 1251:10.5435/00124635-200704000-00004 916:. April 27, 2011. Archived from 762: 713:removal of the affected testicle 633:, the typical symptom is severe 345:can occur as a result of severe 114: 1273: 436:tissue that is associated with 1121: 1096: 1061: 1009: 985: 971: 959: 932: 898: 353:that can lead to irreversible 1: 1324:The dictionary definition of 891: 870: 302:wherein the solidity of the 7: 1212:The Journal of Rheumatology 519:following the rupture of a 10: 1540: 1082:10.1517/13543784.8.11.1907 906:"Definition of Infarction" 669:skeletal muscle infarction 608:: Pulmonary infarction or 226:are risk factors for both 18: 1448: 1410: 1337: 839:Antiphospholipid syndrome 695:osteochondritis dissecans 404:loose tissues that allow 349:as illustrated in severe 322:) that can flow into the 105: 61: 49: 40: 35: 629:. Although it can occur 419:(lung, small intestines) 19:Not to be confused with 745:is generally caused by 655:is an infarction of an 600:subarachnoid hemorrhage 511:), commonly known as a 371:or other loose organs ( 367:) generally affect the 228:atherosclerotic plaques 84:inadequate blood supply 733:central retinal artery 724: 707:is commonly caused by 574: 491: 272: 259: 216: 190:atherosclerotic plaque 1165:) CS1 maint: others ( 997:www.sciencedirect.com 944:TheFreeDictionary.com 722: 703:: an infarction of a 560: 505:Myocardial infarction 485: 474:organ transplantation 446:myocardial infarction 270: 257: 214: 206:myocardial infarction 1316:at Wikimedia Commons 1182:The American Surgeon 849:Giant-cell arteritis 786:improve this section 535:) in the wall of an 415:tissues with a dual 365:hemorrhagic infarcts 351:Raynaud's phenomenon 236:extracellular matrix 138:improve this section 1031:1993Natur.365..654S 920:on January 23, 2014 865:Sickle-cell disease 754:Associated diseases 747:mesenteric ischemia 596:cerebral hemorrhage 583:Cerebral infarction 454:cerebral infarction 102:, "stuffed into"). 725: 709:testicular torsion 687:avascular necrosis 665:arterial embolisms 619:Splenic infarction 575: 527:(fatty acids) and 492: 417:circulatory system 408:to collect in the 273: 260: 217: 1506: 1505: 1366: 1365: 1312:Media related to 1140:978-1-4557-2613-4 1076:(11): 1907–1916. 822: 821: 814: 673:diabetes mellitus 663:. Causes include 529:white blood cells 387:consists more of 284:White infarctions 263:By histopathology 174: 173: 166: 78:is tissue death ( 73: 72: 30:Medical condition 1531: 1393: 1386: 1379: 1370: 1369: 1335: 1334: 1323: 1311: 1295: 1294: 1292: 1291: 1277: 1271: 1270: 1234: 1228: 1227: 1207: 1198: 1197: 1177: 1171: 1170: 1160: 1152: 1125: 1119: 1118: 1100: 1094: 1093: 1065: 1059: 1058: 1039:10.1038/365654a0 1013: 1007: 1006: 1004: 1003: 989: 983: 982: 975: 969: 963: 957: 947: 936: 930: 929: 927: 925: 902: 817: 810: 806: 803: 797: 766: 758: 743:Bowel infarction 711:and may require 681:: Infarction of 631:asymptomatically 621:occurs when the 539:. The resulting 432:) of previously 381:small intestines 347:vasoconstriction 182:arterial embolus 169: 162: 158: 155: 149: 118: 110: 94:. The resulting 92:vasoconstriction 88:artery blockages 45: 33: 32: 1539: 1538: 1534: 1533: 1532: 1530: 1529: 1528: 1524:Causes of death 1519:Gross pathology 1509: 1508: 1507: 1502: 1444: 1438:Small intestine 1433:Large intestine 1406: 1397: 1367: 1362: 1361: 1346: 1304: 1299: 1298: 1289: 1287: 1279: 1278: 1274: 1235: 1231: 1208: 1201: 1178: 1174: 1154: 1153: 1141: 1127: 1126: 1122: 1115: 1101: 1097: 1066: 1062: 1025:(6447): 654–7. 1014: 1010: 1001: 999: 991: 990: 986: 977: 976: 972: 964: 960: 938: 937: 933: 923: 921: 904: 903: 899: 894: 873: 818: 807: 801: 798: 783: 767: 756: 653:Limb infarction 610:lung infarction 545:oxygen shortage 517:coronary artery 497: 495:By localization 460:, replantation 398:occlusion of a 389:red blood cells 361:Red infarctions 341:and consequent 288:anemic infarcts 265: 252: 232:thromboembolism 224:atherosclerosis 170: 159: 153: 150: 135: 119: 108: 31: 28: 17: 12: 11: 5: 1537: 1527: 1526: 1521: 1504: 1503: 1501: 1500: 1495: 1494: 1493: 1488: 1483: 1478: 1470: 1469: 1468: 1463: 1454: 1452: 1446: 1445: 1443: 1442: 1441: 1440: 1435: 1430: 1425: 1416: 1414: 1408: 1407: 1396: 1395: 1388: 1381: 1373: 1364: 1363: 1360: 1359: 1347: 1342: 1341: 1339: 1338:Classification 1332: 1331: 1317: 1303: 1302:External links 1300: 1297: 1296: 1272: 1229: 1199: 1172: 1139: 1120: 1113: 1095: 1060: 1008: 984: 970: 958: 956: 955: 952: 931: 896: 895: 893: 890: 872: 869: 868: 867: 862: 857: 852: 846: 841: 836: 820: 819: 770: 768: 761: 755: 752: 751: 750: 736: 717: 716: 698: 676: 646: 623:splenic artery 612: 603: 555: 554: 496: 493: 480: 479: 478: 477: 423: 420: 413: 402: 358: 264: 261: 251: 250:Classification 248: 172: 171: 122: 120: 113: 107: 104: 71: 70: 65: 59: 58: 47: 46: 38: 37: 29: 15: 9: 6: 4: 3: 2: 1536: 1525: 1522: 1520: 1517: 1516: 1514: 1499: 1496: 1492: 1489: 1487: 1484: 1482: 1479: 1477: 1474: 1473: 1471: 1467: 1464: 1462: 1459: 1458: 1456: 1455: 1453: 1451: 1447: 1439: 1436: 1434: 1431: 1429: 1426: 1424: 1421: 1420: 1418: 1417: 1415: 1413: 1409: 1405: 1401: 1394: 1389: 1387: 1382: 1380: 1375: 1374: 1371: 1358: 1354: 1353: 1349: 1348: 1345: 1340: 1336: 1330:at Wiktionary 1329: 1328: 1322: 1318: 1315: 1310: 1306: 1305: 1286: 1282: 1276: 1268: 1264: 1260: 1256: 1252: 1248: 1245:(4): 208–17. 1244: 1240: 1233: 1225: 1221: 1218:(4): 1063–8. 1217: 1213: 1206: 1204: 1195: 1191: 1187: 1183: 1176: 1168: 1164: 1158: 1150: 1146: 1142: 1136: 1132: 1131: 1124: 1116: 1114:0-07-141620-X 1110: 1106: 1099: 1091: 1087: 1083: 1079: 1075: 1071: 1064: 1056: 1052: 1048: 1044: 1040: 1036: 1032: 1028: 1024: 1020: 1012: 998: 994: 988: 980: 974: 967: 962: 953: 950: 949: 945: 941: 935: 919: 915: 911: 907: 901: 897: 889: 888: 883: 881: 876: 866: 863: 861: 858: 856: 853: 850: 847: 845: 842: 840: 837: 834: 830: 827: 826: 825: 816: 813: 805: 795: 791: 787: 781: 780: 776: 771:This section 769: 765: 760: 759: 748: 744: 740: 737: 734: 730: 727: 726: 721: 714: 710: 706: 702: 699: 696: 692: 688: 684: 680: 677: 674: 670: 666: 662: 658: 654: 650: 647: 644: 643:acute abdomen 640: 636: 632: 628: 624: 620: 616: 613: 611: 607: 604: 601: 597: 592: 588: 584: 580: 577: 576: 572: 568: 564: 563:H&E stain 559: 552: 551: 546: 542: 538: 534: 530: 526: 522: 518: 514: 510: 506: 502: 499: 498: 489: 484: 475: 471: 467: 463: 459: 458:resuscitation 455: 451: 447: 443: 439: 435: 431: 427: 424: 421: 418: 414: 411: 407: 403: 401: 397: 396: 394: 390: 386: 382: 378: 374: 370: 366: 362: 359: 356: 352: 348: 344: 340: 336: 332: 329: 325: 321: 317: 313: 309: 305: 301: 297: 293: 289: 285: 282: 281: 280: 278: 269: 256: 247: 245: 241: 237: 233: 229: 225: 221: 213: 209: 207: 203: 199: 195: 191: 187: 183: 179: 168: 165: 157: 147: 143: 139: 133: 132: 128: 123:This section 121: 117: 112: 111: 103: 101: 97: 93: 89: 85: 81: 77: 69: 66: 64: 60: 56: 55:H&E stain 52: 48: 44: 39: 34: 26: 22: 1449: 1403: 1350: 1326: 1288:. Retrieved 1284: 1275: 1242: 1238: 1232: 1215: 1211: 1188:(2): 182–8. 1185: 1181: 1175: 1129: 1123: 1104: 1098: 1073: 1069: 1063: 1022: 1018: 1011: 1000:. Retrieved 996: 987: 973: 961: 934: 922:. Retrieved 918:the original 909: 900: 884: 877: 874: 823: 808: 799: 784:Please help 772: 738: 728: 700: 678: 668: 648: 614: 605: 578: 548: 531:(especially 513:heart attack 512: 508: 500: 274: 220:Hypertension 218: 175: 160: 151: 136:Please help 124: 99: 75: 74: 1466:Hemorrhagic 1285:Mayo Clinic 910:MedicineNet 685:results in 567:neutrophils 533:macrophages 438:reperfusion 426:reperfusion 154:August 2011 1513:Categories 1450:Infarction 1404:infarction 1327:infarction 1314:Infarction 1290:2021-08-10 1002:2023-04-01 924:August 19, 892:References 627:blood clot 550:myocardium 444:, such as 339:blood flow 333:. Similar 76:Infarction 51:Micrograph 36:Infarction 25:Infraction 1472:Location 1419:Location 1400:Ischaemia 1157:cite book 1149:879416939 940:"infarct" 871:First aid 773:does not 466:frostbite 456:), shock- 440:-related 410:infarcted 385:occlusion 335:occlusion 328:ischaemic 279:present: 240:occluding 125:does not 100:infarctus 82:) due to 68:Pathology 63:Specialty 21:Infection 1498:Gangrene 1412:Ischemia 1267:31296534 1259:17426292 1224:10782838 1090:11139833 948:Citing: 860:Volvulus 833:gangrene 802:May 2013 705:testicle 701:Testicle 589:kind of 587:ischemic 571:neuropil 541:ischemia 442:diseases 434:ischemic 355:gangrene 343:necrosis 331:necrosis 198:volvulus 186:thrombus 178:ischemia 80:necrosis 1357:D007238 1194:9486895 1055:4282441 1047:8413628 1027:Bibcode 966:infract 794:removed 779:sources 637:in the 585:is the 488:H&E 462:surgery 383:). The 316:glucose 300:kidneys 244:embolus 146:removed 131:sources 1486:Spleen 1461:Anemic 1457:Types 1265:  1257:  1222:  1192:  1147:  1137:  1111:  1088:  1053:  1045:  1019:Nature 855:Hernia 844:Sepsis 615:Spleen 591:stroke 537:artery 525:lipids 490:stain. 472:, and 450:stroke 430:injury 393:fibrin 373:testis 312:oxygen 304:tissue 292:spleen 202:hernia 106:Causes 96:lesion 1481:Brain 1476:Heart 1428:Heart 1423:Brain 1263:S2CID 1051:S2CID 914:WebMD 851:(GCA) 739:Bowel 691:joint 579:Brain 501:Heart 470:burns 406:blood 377:ovary 369:lungs 308:blood 296:heart 277:blood 200:, or 194:tumor 188:, or 1491:Limb 1402:and 1352:MeSH 1255:PMID 1220:PMID 1190:PMID 1167:link 1163:link 1145:OCLC 1135:ISBN 1109:ISBN 1086:PMID 1043:PMID 926:2011 777:any 775:cite 683:bone 679:Bone 667:and 649:Limb 635:pain 606:Lung 598:and 412:zone 400:vein 391:and 324:area 320:fuel 298:and 230:and 222:and 129:any 127:cite 1247:doi 1078:doi 1035:doi 1023:365 788:by 729:Eye 661:leg 659:or 657:arm 337:to 326:of 208:). 140:by 23:or 1515:: 1355:: 1283:. 1261:. 1253:. 1243:15 1241:. 1216:27 1214:. 1202:^ 1186:64 1184:. 1159:}} 1155:{{ 1143:. 1084:. 1072:. 1049:. 1041:. 1033:. 1021:. 995:. 942:. 912:. 908:. 882:. 741:: 697:). 651:: 617:: 581:: 553:). 509:MI 503:: 468:, 464:, 448:, 379:, 375:, 294:, 196:, 184:, 1392:e 1385:t 1378:v 1344:D 1293:. 1269:. 1249:: 1226:. 1196:. 1169:) 1151:. 1117:. 1092:. 1080:: 1074:8 1057:. 1037:: 1029:: 1005:. 981:. 946:. 928:. 835:) 815:) 809:( 804:) 800:( 796:. 782:. 645:. 573:. 507:( 476:. 452:( 428:( 363:( 357:. 318:/ 314:/ 310:/ 286:( 167:) 161:( 156:) 152:( 148:. 134:. 57:. 27:.

Index

Infection
Infraction

Micrograph
H&E stain
Specialty
Pathology
necrosis
inadequate blood supply
artery blockages
vasoconstriction
lesion

cite
sources
improve this section
adding citations to reliable sources
removed
Learn how and when to remove this message
ischemia
arterial embolus
thrombus
atherosclerotic plaque
tumor
volvulus
hernia
myocardial infarction

Hypertension
atherosclerosis

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