756:
Martin L, Gorman M, Thomas H, Peto J, Bishop DT, Gray R, Maher ER, Lucassen A, Kerr D, Evans DGR, The CORGI Consortium, Schafmeyer C, Buch S, Völzke H, Hampe J, Schreiber S, John U, Kössler T, Pharoah P, van Wezel T, Morreau H, Wijnen JT, Hopper JL, Southey MC, Giles GG, Severi G, Catellvi-Bel S, Ruiz-Ponte C, Carracedo A, Castells A, The EPICOLON Consortium, Foersti A, Hemminki K, Vodicka P, Naccarati A, Lipton L, Ho JWC, Cheng KK, Sham PC, Luk J, Agundez JAG, Ladero JM, de la Hoya M, Caldés T, Niittymäki I, Tuupanene S, Karhu A, Aaltonen L, Cazier JB, Campbell H, Dunlop MG, Houlston RS. A genome-wide association study identifies novel colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3. Nat
Genetics 2008;40:623-630
741:
AH, Gwilliam R, Hall AS, Hammond N, Hengstenberg C, Illig T, König IR, Knouff CR, McPherson R, Melander O, Mooser V, Nauck M, Nieminen MS, O’Donnell CJ, Peltonen L, Potter SC, Prokisch H, Rader DJ, Rice CM, Roberts R, Salomaa V, Sambrook J, Schreiber S, Schunkert H, Schwartz SM, Serbanovic-Canic J, Sinisalo J, Siscovick DS, Stark K, Stephens J, Thompson JR, Völker U, Völzke H, Watkins NA, Wells GA, Wichmann HE, Heel DV, Tyler-Smith C, Thein SL, Kathiresan S, Perola M, Reilly MP, Stewart AF, Erdmann J, Samani NJ, Meisinger C, Greinacher A, Deloukas P, Ouwehand WH, Gieger C. A meta-analysis of eight haematological parameters identifies 22 associated loci and extensive disease pleiotropy on chromosome 12q24. Nat
Genetics, in press
760:
D, Haritunians T, Deckers JW, Stritzke J, Lackner KJ, Völker U, Ingelsson E, Iftikhar K, Härting J, O’Donnell CJ, Heckbert SR, Stricker BH, Ziegler A, Reffelmann T, Redfield MM, Werdan K, Mitchell GF, Rice K, Arnett D, Hofman A, Gottdiener JS, Uitterlinden AG, Meitinger T, Blettner M, Friedrich N, Wang TJ, Psaty BM, van Duijn CM, Wichmann HE, Munzel TF, Kroemer HK, Benjamin EJ, Rotter JI, Witteman JC, Schunkert H, Schmidt H, Völzke H, Blankenberg S. Novel genetic variants associated with cardiac structure and function: Genome-wide association findings of a prospective meta-analysis from the EchoGen
Consortium. JAMA; in press
506:
accepted by the local ethics committee. Participants with category IV findings are immediately transferred to a clinical specialist. Cases with positive findings of category II and III are referred to an
Advisory Board established when the study began. and having as permanent members specialists from medical, surgical, neurological, epidemiological and radiological departments. Upon presentation of cases they reach a consensus about whether to recommend further clinical work-up or not. Participants in whom relevant findings are made get informed about the abnormality and recommendation of the Advisory Board.
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670:
J, Prokisch H, Salo P, Salomaa V, Samani N, Schlessinger D, Uda M, Völker U, Wäber G, Waterwoth D, Wang-Sattler R, Writh AF, Adamski J, Whitfield JB, Gyllensten U, Wilson JF, Rudan I, Pramstaller P, Watkins H, Döring A, Wichmann HE, Spector TD, Peltonen L, Völzke H, Nagaraja R, Vollenweider P, Caulfield M, Illig T, Gieger C. Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations. PLOS Genetics; in press
662:
L, Tomlinson IP, Farrington SM, Tenesa A, Prendergast JGD, Barnetson RA, Cetnarskyj R, Porteous ME, Pharoah PD, Kössler T, Hampe J, Buch S, Schafmayer C, Tepel J, Schreiber S, Völzke H, Chang-Claude J, Hoffmeister M, Brenner H, Zanke BW, Montpetit A, Hudson TJ, Gallinger S, Campbell H, Dunlop MG. Meta-analysis of genome-wide association data identifies 4 novel susceptibility loci for colorectal cancer. Nat
Genetics 2008; 40: 1426 - 1435
401:
759:
Vasan RS, Glazer NL, Felix JF, Lieb W, Wild PS, Felix SB, Watzinger N, Larson MG, Smith NL, Dehghan A, Großhennig A, Schillert A, Teumer A, Schmidt R, Kathiresan S, Lumley T, Aulchenko YS, König IR, Zeller T, Homuth G, Struchalin M, Aragam J, Bis JC, Rivadeneira J, Erdmann J, Dörr M, Greiser KH, Levy
669:
Kolz M, Johnson T, Sanna S, Teumer A, Vitart V, Perola M, Mangino M, Albrecht E, Wallace C, Farrall M, Johansson A, Nyholt DR, Aulchenko Y, Beckmann JS, Bergmann S, Bochud M, Brown M, Campbell H, Connell J, Dominiczak A, Homuth G, Lamina C, McCarthy MI, Meitinger T, Mooser V, Munroe P, Nauck M, Peden
661:
Houlston RS, Webb E, Broderick P, Pittman MA, Di
Bernardo MC, Lubbe S, Chandler I, Vijayakrishnan j, Sullivan K, Penegar S, Carvajal-Carmona L, Howarth K, Jäger E, Spain S, Walther A, Barclay E, Martin L, Gorman M, Domingo E, Teixeira A, Kerr D, Cazier JB, Niittymäki I, Tuupanene S, Karhu A, Aaltonen
740:
Soranzo N, Spector TD, Mangino M, Kühnel B, Rendon A, Teumer A, Willenborg C, Wright B, Chen L, Li M, Salo P, Voight BF, Burns P, Laskowski RA, Xue Y, Menzel S, Altshuler D, Bradley JR, Bumpstead S, Burnett MS, Devaney J, Döring A, Elosua R, Epstein S, Erber W, Falchi M, Garner SF, Ghori MJ, Goodall
681:
Newton-Cheh C, Johnson T, Gateva V, Tobin MD, Bochud M, Coin L, Najjar SS, Zhao JH, Heath SC, Eyheramendy S, Papadakis K, Voight BF, Scott LJ, Zhang F, Farrall M, Tanaka T, Wallace C, Chambers JC, Khaw KT, Nilsson P, Van Der Harst P, Polidoro S, Grobbee DE, Onland-Moret NC, Bots ML, Wain LV, Elliott
676:
Meisinger C, Gieger C, Prokisch H, Soranzo Z, Mehta D, Rosskopf D, Lichtner P, Klopp N, Stephens J, Watkins NA, Ouwehand WH, Deloukas P, Greinacher A, Koenig W, Nauck M, Rimmbach C, Völzke H, Peters A, Illig T, Meitinger T, Wichmann HE, Döring A. A genome-wide association study identifies three loci
607:
Buch S, Schafmeyer C, Völzke H, Becker C, Franke A, von
Eberstein H, Kluck C, Bäßmann I, Brosch M, Lammert F, Miquel JF, Nervi F, Wittig M, Rosskopf D, Timm B, Höll C, Seeger M, ElSharawy A, Fändrich F, Fölsch UR, Krawczak M, Schreiber S, Nürnberg P, Tepel J, Hampe J. A genome-wide association scan
505:
Pathological findings are categorized using the method chosen by Bryan et al. for the
Cardiovascular Health Study. This method classifies all findings into 4 basic categories. The management of pathological findings and communication with study participants are defined in a standardized protocol
755:
Tomlinson IPM, Webb E, Carvajal-Carmona L, Broderick P, Howarth K, Pittman AM, Spain S, Lubbe S, Walther A, Sullivan K, Jaeger E, Fielding S, Rowan A, Vijayakrishnan J, Domingo E, Chandler I, Kemp Z, Qureshi M, Farrington SM, Tenesa A, Prendergast JGD, Bametson RA, Penegar S, Barclay E, Wood W,
747:
Tenesa A, Farrington SM, Prendergast JGD, Porteous ME, Walker M, Haq N, Barnetson RA, Theodoratou E, Cetnarskyj R, Cartwright N, Wilson R, Semple C, Clarke AJ, Reid FJL, Smith LA, Kavoussanakis K, Kossler T, Pharoah PDP, Buch S, Schafmayer C, Tepel J, Schreiber S, Völzke H, Schmidt CO, Hampe J,
618:
Döring A, Gieger C, Mehta D, Gohlke H, Prokisch H, Coassin S, Fischer G, Henke K, Klopp N, Kronenberg F, Paulweber B, Pfeufer A, Rosskopf D, Völzke H, Illig T, Meitinger T, Wichmann HE, Meisinger C. SLC2A9 influences uric acid concentrations with pronounced gender-specific effects. Nat
Genetics
634:
Friedrich N, Haring R, Nauck M, Lüdemann J, Spilcke-Liss E, Felix SB, Dörr M, Brabant G, Völzke H, Wallaschofski H. Serum insulin-like growth factor-1, insulin-like growth factor binding protein-3 and mortality: results of the Study of Health in
Pomerania. J Clin Endocrinol Metab; in
646:
Grabe HJ, Spitzer C, Schwahn C, Barnow S, Lucht M, Freyberger HJ, John U, Wallaschofski H, Völzke H, Rosskopf D. The serotonin transporter gene promoter polymorphism (SLC6A4) and the susceptibility to posttraumatic stress disorder in the general population. Am J Psychiatr; in
642:
Grabe HJ, Lange M, Wolff B, Völzke H, Alte D, Lucht M, Freyberger HJ, John U, Cascorbi I. Mental and physical distress is modulated by a polymorphism in the 5-HT transporter gene interacting with social stressors and chronic disease burden. Mol Psychiatr
799:
Wolff B, Völzke H, Lüdemann J, Robinson DM, Vogelgesang D, Staudt A, Kessler C, Dahm JB, John U, Felix SB. Association between high serum ferritin levels and carotid atherosclerosis in the Study of Health in Pomerania (SHIP). Stroke 2004;35:453 -
665:
Koch B, Schäper C, Ittermann T, Spielhagen T, Völzke H, Ewert R, Gläser S. Reference values and ranges for cardiopulmonary exercise testing in a general adult population- results of the Study of Health in Pomerania. Eur Resp J 2009; 33: 389 -
638:
Gläser S, Friedrich N, Ewert R, Schäper C, Nauck M, Dörr M, Völzke H, Felix SB, Wallaschofski H, Koch B. Association between IGF-1 and IGFBP3 and lung function: results of the Study of Health in Pomerania. J Clin Endocrinol Metab; in
748:
Wilkening S, Canzian F, Chang-Claude J, Hoffmeister M, Brenner H, Capella G, Moreno V, Deary IJ, Starr JM, Tomlinson IPM, Webb E, Houlston RS, Rennert G, Ballinger D, Rozek L, Gruber SB, Matsuda K, Kidokoro T, Nakamura Y, Zanke BW,
654:
Haring R, Völzke H, Felix SB, Schipf S, Dörr M, Rosskopf D, Nauck M, Schöfl C, Wallaschofski H. Prediction of metabolic syndrome by low serum testosterone levels in men: Results from the Study of Health in Pomerania. Diabetes; in
795:
Völzke H, Robinson D, Spielhagen T, Nauck M, Obst A, Ewert A, Wolff B, Wallaschofski H, Felix SB, Dörr M. Serum thyrotropin levels within the reference range are associated with endothelial function. Eur Heart J 2009; 30: 217 –
501:
review all scans independently to evaluated images for presence or absence of pathological findings. In case of a difference between the two observer a third reading is performed to reach a consensus on the discrepant finding.
803:
Wolff B, Völzke H, Robinson D, Schwahn C, Vogelgesang D, Dahm JB, Kessler C, John U, Felix SB. Relation of parity with common carotid intima-media thickness among women of the Study of Health in Pomerania (SHIP). Stroke
766:
Völzke H, Werner A, Wallaschofski H, Friedrich N, Robinson DM, Kindler S, Kraft M, John U, Hoffmann W. Occupational exposure to ionizing radiation is associated with autoimmune thyroid disease. J Clin Endocrinol Metab
650:
Haring R, Wallaschofski H, Nauck M, Dörr M, Baumeister SE, Völzke H. Ultrasonographic hepatic steatosis increased prediction of mortality risk from elevated serum gamma-glutamyl transpeptidase levels. Hepatology; in
788:
Völzke H, Friedrich N, Schipf S, Haring R, Lüdemann J, Nauck M, Dörr M, Brabant G, Wallaschofski H. Association between serum IGF-1 levels and thyroid disorders in a population-based study. J Clin Endocrinol Metab
625:
Dörr M, Vogelgesang D, Robinson DM, Kors JA, Felix SB, Völzke H. Thyroid function is associated with short rate-adjusted QT intervals. Results from a population-based study. J Clin Endocrinol Metab 2006;91:4938-494
611:
Baumeister SE, Völzke H, Marschall P, John U, Schmidt CO, Alte D. Impact of fatty liver disease on health care utilization and costs in the general population: a 5-year observation. Gastroenterology 2008;134:85-94
737:
Schmidt CO, Alte D, Sauer S, Völzke H, Friedrich N, Valliant R. (in press) Partial misspecification of survey design features sufficed to severely bias estimates of health related outcomes. J Clin Epidemiology.
773:
Völzke H, Schwahn C, Dörr M, Schwarz S, Robinson D, Dören M, Felix SB, John U, Kocher T. Gender differences in the relation between number of teeth and systolic blood pressure. J Hypertens 2006; 24: 1257-1263
658:
Hegenscheid K, Kühn JP, Völzke H, Biffar R, Hosten N, Puls R. Whole-body magnetic resonance imaging of healthy volunteers: pilot study results from the population-based SHIP study. Rofo. 2009;181(8):748-59.
622:
Dörr M, Wolff B, Robinson DM, John U, Lüdemann J, Meng W, Felix SB, Völzke H. The association of thyroid function with cardiac mass and left ventricular hypertrophy. J Clin Endocrinol Metab 2005;90:673-677
614:
Desvarieux M, Schwahn C, Völzke H, Demmer RT, Lüdemann J, Kessler C, Jacobs DR, John U, Kocher T. Gender differences in the relationship between periodontal disease, tooth loss and atherosclerosis. Stroke
894:
Bryan RN, Manolio TA, Schertz LD et al.(1994). "A method for using MR to evaluate the effects of cardiovascular disease on the brain: the cardiovascular health study". AJNR Am J Neuroradiol;15:1625-1633.
779:
Völzke H, Alte D, Dörr M, Wallaschofski H, John U, Felix SB, Rettig R. The association between subclinical hyperthyroidism and blood pressure in a population-based study. J Hypertens 2006;24:1947-1953
631:
Friedrich N, Völzke H, Hampe J, Lerch M, Jorgensen T. Known risk factors do not explain disparities in gallstone prevalence between Denmark and Northeast Germany. Am J Gastroenterol 2009; 104: 89 - 95
752:, Rangrej J, Kustra R, Montpetit A, Hudson TJ, Gallinger S, Campbell H, Dunlop MG. A genome-wide association scan identifies three colorectal cancer susceptibility loci. Nat Genetics 2008;40:631-637
461:(3)To correlate MR findings with clinical examination results, metabolomic and genome-wide analysis in order to help elucidate the complex associations that exist between risk factors and diseases.
785:
Völzke H, Schwarz S, Baumeister SE, Wallaschofski H, Schwahn C, Grabe HJ, Kohlmann T, John U, Dören M. Menopausal status and hepatic steatosis in a general female population. Gut 2007; 56: 594-595
770:
Völzke H, Warnke C, Dörr M, Kramer A, Gürtler L, Hoffmann W, Kors JA, John U, Felix SB. Prior history of diphtheria and current cardiac disorders. Eur J Clin Microbiol Infect Dis 2006; 25: 651-656
628:
Dörr M, Robinson DM, Wallaschofski H, Schwahn C, John U, Felix SB, Völzke H. Low serum thyrotropin is associated with high plasma fibrinogen. J Clin Endocrinol Metab 2006; 91: 530-534
673:
Meisinger C, Heier M, Völzke H, Löwel H, Mitusch R, Lüdemann J, Hense HW. Regional disparities of hypertension prevalence and management within Germany. J Hypertens 2006; 24: 293-299
763:
Völzke H, Robinson DM, Schminke U, Lüdemann J, Rettig R, Felix SB, Kessler C, John U, Meng W. Thyroid function and carotid wall thickness. J Clin Endocrinol Metab 2004;89:2145-2149
582:, Ministry of Cultural Affairs as well as the Social Ministry of the Federal State of Mecklenburg-West Pomerania, Federal Ministry of Nutrition, Agriculture and Consumer’s Safety,
598:(Mainz, Germany), Data Input GmbH (Darmstadt, Germany), GABA International AG (Therwil, Switzerland), Imedos Systems (Jena, Germany) and Heinen and Löwenstein (Bad Ems, Germany).
891:(2001). "Study of Health in Pomerania (SHIP) - A health examination survey in an east German region: Objectives and design". Sozial- und Präventivmedizin 46(3): 186-194.
744:
Spitzer C, Barnow S, Völzke H, John U, Freyberger HJ, Grabe HJ. Trauma and Postraumatic Stress Disorder in an elderly community sample. J Clin Psychiatr 2008;69:693-700
579:
822:
Habes M, Schiller T, Rosenberg C, Burchardt M, Hoffmann W (2013). "Automated prostate segmentation in whole-body MRI scans for epidemiological studies".
243:
SHIP-1 follow-up examination: SHIP-0 participants were invited again. The first 5-year-follow-up was conducted between October 2002 and September 2006.
734:
Puls R, Hamm B, Hosten N. MRT ohne Radiologen - Ethische Aspekte bei bevölkerungsbasierten Studien mit MR-Untersuchungen. Rofo. 2010; 182:469-471
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of the probands. Additionally diagnostic interviews were performed to diagnose current and lifetime mental disorders (DSM-IV). A broad range of
608:
identifies the hepatic cholesterol transporter ABCG5/ABCG8 as a susceptibility factor for human gallstone disease. Nat Genetics 2007;39:995-999
469:
Additionally to the standard whole-body MRI protocol (right figure) men have the option to undergo contrast-enhanced cardiac MRI and MR
776:
Völzke H, Hoffmann W. Radiation exposure and thyroid disorders in Hiroshima and Nagasaki atomic bomb survivors. JAMA 2006;296:512-513
542:. SHIP is the basis for this research. Between July 2007 and August 2010 n=2393 probands were interviewed. The interviewer assessed
939:
729:
454:. Clinical MR reference parameters currently in use were derived from small, nonrepresentative samples and are thus prone to
594:
AG, Health Care Sector (Erlangen, Germany), Pfizer Pharma GmbH (SBU Endocrinology and Ophthalmology; Berlin Germany),
67:
45:
38:
934:
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583:
586:, Competence Network Heart Failure, Competence Network Diabetes, German Asthma and COPD Network, Genopathomik,
148:
The aims of both studies are: (i) investigation of the long-term progression of subclinical findings, their
877:(2009). "Cohort Profile: The Study of Health in Pomerania". International Journal of Epidemiology;1–14.
423:
394:
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Puls R, Hosten N. (Hrgs.) Zufallsbefunde in der Ganzkörper-MRT. ABW Wissenschaftsverlag Berlin 2010,
121:
32:
246:
SHIP-2 follow-up examination: The 11-year follow-up has started in June 2008 and was completed in
566:(Toronto Alexithymia Scale 20), aversive childhood conditions (Childhood Trauma Questionnaire),
208:
49:
269:
The following table shows all the instruments which are integrated in the SHIP examination.
152:
and prognostic values (SHIP-2); (ii) analysis of the secular trend of subclinical and overt
833:
547:
8:
904:
837:
929:
857:
845:
708:
683:
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Völzke H. Mortality in patients with hepatitis B or hepatitis C. Lancet 2006;368:1767
849:
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360:
302:
212:
204:
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with highly innovative non-invasive methods in the high-risk population of northeast
684:"Genome-wide association study identifies eight loci associated with blood pressure"
570:(Beck Depression Inventory-2), resilience (RS-25) and personality traits (NEO-FFI).
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pression; its main aim is the identification of genetic factors which interact with
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are excluded from the contrast-enhanced modules and only undergo standard protocol.
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455:
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Völzke H. Hyperthyroidism and mortality. . J Am Coll Cardiol 2007;49:2229-2230
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in a high-risk population (SHIP-TREND vs SHIP-0); and (iii) assessment of the
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in all its aspects and complexity involving the collection and assessment of
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Greifswald Approach to Individualized Medicine (GANI_MED)- official homepage
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SHIP-0: Data collection was conducted between October 1997 and May 2001.
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standardized whole-body MR imaging protocol for all participants of SHIP
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associated with mean platelet volume. Am J Hum Genet 2009; 84: 66 - 71
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333:
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are collected for the second examination follow-up of the first SHIP
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and 29 communities in the surrounding region which is part of
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aged 20–79 years was drawn for SHIP-TREND in the same area.
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parts such as left and right ventricular size or volume of
397:. The aims of the following main whole body-MRI study are:
226:
113:
108:. The SHIP study´s main aims include the investigation of
276:
instruments integrated in the examination program of SHIP
172:
905:
Study of Health in Pomerania (SHIP)- official homepage
233:(SHIP-2) and baseline examinations of the second SHIP
590:, Alexander v. Humboldt Foundation, Leibniz Society,
92:(SHIP and SHIP-TREND). The SHIP investigates common
538:and traumatic events to increase the risk of major
380:
493:Assessment of Pathological Findings and Management
412:estimates for different MR findings in a general
921:
292:instruments integrated in the interviews of SHIP
257:, which was examined between September 2008 and
588:Alfried Krupp von Bohlen und Halbach Foundation
253:SHIP-Trend-0: A new sample was drawn for a new
175:aged 20 to 79 years was drawn in the cities of
104:. The study is not interested in one specific
284:self-report questionnaires integrated in SHIP
218:A separate stratified random sample of 8016
815:
682:KS, Teumer A, Luan JA, et al. (2009).
580:Federal Ministry of Education and Research
578:SHIP is funded by following institutions:
707:
68:Learn how and when to remove this message
399:
287:
279:
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139:
31:This article includes a list of general
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164:of subclinical findings (SHIP-TREND).
96:, subclinical disorders and manifest
88:study consisting of two independent
17:
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13:
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37:it lacks sufficient corresponding
14:
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562:were administered to assess e.g.
426:reference parameters for various
422:(2)To establish population-based
373:nearly 50% - 60% indicate these
381:Magnetic resonance imaging (MRI)
22:
915:Institut für Community Medicine
825:Physics in Medicine and Biology
601:
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339:are very common and 30% of all
191:, a region in the northeast of
124:of common, population-relevant
940:Epidemiological study projects
332:than in other German regions.
1:
873:Völzke H, Alte D, Schmidt CO
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207:is the north-eastern part of
167:For SHIP-0, a sample of 7008
84:(SHIP) is a population-based
846:10.1088/0031-9155/58/17/5899
82:Study of Health in Pomerania
7:
481:. Participants with a drug
10:
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584:German Research Foundation
573:
485:or allergy to any kind of
530:vironment interaction in
393:worldwide which includes
135:
199:in the north and to the
144:study region of the SHIP
514:SHIP-LEGEND stands for
52:more precise citations.
935:Public health research
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369:. In the Northeast of
359:is much higher in the
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209:Mecklenburg-Vorpommern
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213:federal German states
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540:depressive disorders
838:2013PMB....58.5899H
477:cardiac MRI and MR
883:10.1093/ije/dyp394
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385:SHIP is the first
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195:, adjacent to the
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832:(17): 5899–5915.
789:2007;92:4039-4045
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297:Previous results
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560:questionnaires
511:
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487:contrast agent
466:
463:
456:selection bias
408:(1)To provide
395:whole-body MRI
382:
379:
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237:(SHIP-TREND).
205:West Pomerania
189:West Pomerania
137:
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4:
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750:Greenwood CMT
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602:Publications
596:Novo Nordisk
577:
531:
527:
523:
519:
515:
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510:Ship-Legende
504:
499:radiologists
497:Two trained
496:
468:
465:MRI Protocol
460:
421:
407:
391:cohort study
384:
353:hypertension
351:of arterial
343:suffer from
314:risk factors
300:
268:
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245:
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158:determinants
150:determinants
147:
130:risk factors
94:risk factors
81:
79:
64:
55:
36:
15:
564:alexithymia
479:mammography
471:angiography
357:hypertrophy
225:Currently,
50:introducing
924:Categories
809:References
568:depression
522:vents and
417:population
410:prevalence
387:population
367:population
349:prevalence
322:overweight
312:of common
310:prevalence
306:population
197:Baltic Sea
177:Greifswald
162:prevalence
156:and their
128:and their
118:prevalence
58:March 2012
33:references
930:Pomerania
556:adulthood
552:childhood
334:Gallstone
330:prevalent
328:are more
181:Stralsund
122:incidence
854:23920310
718:19430483
448:prostate
375:diseases
337:diseases
318:diseases
154:diseases
126:diseases
98:diseases
887:John U
862:9267032
834:Bibcode
709:2891673
592:Siemens
574:Funding
548:traumas
483:allergy
371:Germany
326:obesity
193:Germany
106:disease
102:Germany
90:cohorts
46:improve
889:et al.
875:et al.
860:
852:
728:
716:
706:
544:stress
536:stress
450:, and
444:kidney
440:spleen
428:organs
389:based
347:. The
341:adults
261:2012.
259:summer
255:cohort
250:2012.
248:autumn
235:cohort
231:cohort
220:adults
185:Anklam
136:Design
110:health
35:, but
858:S2CID
655:press
651:press
647:press
639:press
635:press
475:women
436:liver
432:organ
414:adult
364:adult
169:women
850:PMID
726:ISBN
714:PMID
554:and
526:ene-
518:ife-
473:and
430:and
324:and
316:and
301:The
227:data
183:and
171:and
120:and
114:data
80:The
879:doi
842:doi
800:457
796:224
704:PMC
696:doi
666:397
424:MRI
173:men
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524:G
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