416:, and provides independent, external advice on topics that are important to the future of science in the state. His advice includes broadening the state's economy through science and innovation, promoting Western Australia as a science leader nationally and internationally, and acting as an ambassador to raise the awareness of science in the community. He works closely with Science and Innovation in Western Australia to enhance collaboration, attract funding, build leading-edge scientific capability and promote science initiatives across Government, industry and academia. He was heavily involved with the Office of Science in the development of the state's "Science Statement", which identified five key sectors for scientific focus. He also played an important role in the development of the stateβs Science and Innovation Framework, released in 2018. In June 2017, Klinken has been reappointed as Chief Scientist until June 2019.
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397:. During his tenure as Executive Director from 2002 to 2014, the Institute grew from 63 to over 250 researchers and staff, and established a number of spin-off companies including Linear Clinical Research, an early phase-1 clinical trials facility. Under his stewardship, the Institute attracted world-class researchers to Western Australia and made numerous acclaimed medical discoveries. He also spearheaded the $ 200m development of state-of-the-art medical research facilities for the Harry Perkins Institute at the
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Klinken was
Regional Editor of the International Journal of Biochemistry & Cell Biology (1994β2004) and was a member of the Editorial Board of Experimental Haematology (2000β2004). He was invited to be an inaugural member of the International Molecular Biology Network, and has participated in
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Klinken has been a member of the Board of the Cancer
Research Trust since 2009, and is on the Medical Research Advisory Committee of the Australian Cancer Research Foundation, as well as the Scientific Advisory Committee of the Children's Cancer Institute of Australia and the Lions Eye Institute.
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Klinken's research interests include the regulation of red blood cell formation, and the ability of leukaemic cells to develop different features and functions. He has a long-standing interest in identifying genes, which when altered can cause leukaemia and other cancers. During his career on the
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From 1992 to 2005 he provided support to the
National Health and Medical Research Council (NHMRC) of Australia in a variety of roles, and served on the Council of Scotch College, Perth (2003β2008) as well as the Board of the Diabetes Research Foundation (2004β2008).
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genetic causes of cancer, his laboratory team identified two genes (Mlf1 and Hls5) implicated in the development of leukaemias and cancers. His team participated in the
Japanese-led FANTOM5 international consortium that investigated cellular trancriptomics.
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Melbourne 1987β1988. In 1989, he returned to an academic position at UWA, where he received two "Excellence in Teaching" Awards. In 1994 he was appointed UWA Professor of Clinical Biochemistry based at the
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Complementing tissue characterisation by integrating transcriptome profiling from the Human
Protein Atlas and from the FANTOM5 consortium'. NUCLEIC ACIDS RESEARCH, 43, pp. 6787β6798 (2015)
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In vitro derived leukaemic erythroid cell lines induced by a raf/myc retrovirus differentiate in response to erythropoietin. Proc Natl Acad Sci USA 85:8506β8510 (1988)
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Transformation of murine bone marrow cells with a raf/myc retrovirus yields clonally related mature B cells and macrophages. Mol Cell Biol 10:3562β3568 (1990)
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Gain-of-function Lyn induces anaemia: appropriate Lyn activity is essential for normal erythropoiesis and Epo receptor signalling. Blood 122: 262β271 (2013)
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Effect of inhibitors of
Ornithine decarboxylase on retrovirus induced transformation of murine erythroid precursors in vitro. Cancer Res 46:6246β6429 (1986)
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Liar, a novel Lyn-binding nuclear/cytoplasmic shuttling protein that influences erythropoietin-induced differentiation. Blood 113: 3845β3856 (2009)
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Erythropoietin-induced stimulation of differentiation and proliferation in J2E cells is not mimicked by chemical induction. Blood 80:412β419 (1992)
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v-cbl, a new oncogene from a dual-recombinant murine retrovirus that induced early B-lineage lymphomas. Proc Natl Acad Sci USA 86:1168β1172 (1989)
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Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphoma genesis in EΞΌ-myc transgenic mice. Cell 65:1β10 (1991)
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Klinken played a key role in establishing the
Western Australian Institute for Medical Research (WAIMR) in 1998, which later became known as the
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HLS5, a novel RBCC family member isolated from a hemopoietic lineage switch is a candidate tumour suppressor. J Biol Chem 279:8181β8189 (2004)
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Myeloid
Leukemia Factor 1 associates with a novel heterogeneous nuclear ribonucleoprotein U-like molecule. J Biol Chem 281:38791-38800 (2006)
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Maturation of erythroid cells and erythroleukemia development are affected by the kinase activity of Lyn. Cancer Res 61:2453β2458 (2001)
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Evolution of B cell lineage lymphomas in mice with a retrovirus-induced immunodeficiency syndrome MAIDS. J Immunol 140:1123β1131 (1987)
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2016 β Edith Cowan
University (Kurongkurl Katitjin) Black Moon award for his contribution to the indigenous people of Western Australia
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Lyn tyrosine kinase is essential for erythropoietin-induced differentiation of J2E erythroid cells. EMBO Journal 16:1610β1619 (1997)
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Transcriptional enhancers lead waves of co-ordinated transcription in transitioning mammalian cells. Science 347:1010β1014 (2015)
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224:(Western Australia) from 1966 to 1970. In 1975 he obtained a Bachelor of Science (1st Class Honours) in Biochemistry from the
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Hemopoietic lineage conversion: v-raf oncogene converts EΞΌ-myc transgenic B cells into macrophages. Cell 53:857β867 (1988)
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HLS7, a hemopoietic lineage switch gene homologous to the leukaemia-inducing gene MLF1. EMBO Journal 18:5559β5566 (1999)
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2016 β Innovate Australia Award for outstanding contributions to Western Australian science, technology & innovation
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A rapid fatal erythroleukemia caused by J2E cells can be treated ex vivo with erythropoietin. Leukemia 9:900β907 (1995)
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Earth, sea and sky : communicate, collaborate and innovate (Australian Quarterly JulyβSeptember 2015)
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204:(born 30 July 1953 in Singapore) is an Australian medical researcher and academic. He is currently the
360:(Western Australia) from 1981 to 1983. After being awarded his PhD, he received a fellowship from the
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Interviews with James Lush, 720 ABC Perth (31 May 2016, 28 June 2016, 26 July 2016, 16 August 2016)
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Hls5 regulates erythroid differentiation by modulating Gata-1 activity. Blood 111: 1946β1950 (2008)
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Do the hard yakka : WA Chief scientist champions innovative research (WA Today 29 April 2015)
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Interview ABC Radio National β Could βbig dataβ be WAβs next big mining resource (15 July 2016)
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372:(1984β1986). He then returned to Australia and worked as a post-doctoral fellow at the
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228:(UWA). He obtained a PhD in Biochemistry and a Diploma of Education from UWA in 1982.
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2015 β Fellow of the Australian Academy of Health and Medical Sciences (FAHMS)
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In June 2014, the Premier of Western Australia appointed Klinken as the third
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Fellows of the Australian Academy of Technological Sciences and Engineering
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of the state. He currently reports directly to the Minister for Science,
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Innovation in Western Australia (Science meets business, 17 April 2016)
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Australian medical researcher and Chief Scientist of Western Australia
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2016 β 100 most influential Western Australians (The West Australian)
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Collaboration call on biodiversity (Business news, 24 August 2015)
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Interview with Gillian O'Shaughnessy, 720 ABC Perth (5 June 2015)
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Past director of Harry Perkins Institute, Professor Peter Klinken
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Fellows of the Australian Academy of Health and Medical Sciences
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Spotlight on Agriculture's future (Farm Weekly, 3 December 2015)
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Companion (AC) in the General Division of the Order of Australia
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The West Australian (29, 30, 31 December 2015, 4 January 2016)
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from the article and its talk page, especially if potentially
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Erythroid defects in TRa-/- mice. Blood 111: 3245β3248 (2008)
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WA poised to excel in science (West Australian, 28 May 2015)
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Interview with Geoff Hutchison, 720 ABC Perth (11 June 2014)
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A promoter level expression atlas. Nature 507:462β470 (2014)
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Taking the lead β based on science (Focus, ATSE, June 2016)
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2008 β Western Australian Citizen of the Year Award (CitWA)
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Interview 6PR 12 June 2017 β WAβs Chief Scientist honoured
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Back to school with Peter Klinken (Student Edge β YouTube)
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Western Australian Institute for Medical Research (WAIMR)
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10 minutes on leadership (Business News 17 August 2016)
638:. Australian Cancer Research Foundation. Archived from
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2012 β Ernst and Young Social Entrepreneur of the Year
583:, University News, 13 June 2017, www.news.uwa.edu.au
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Australian Academy of Health & Medical Sciences
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Walter and Eliza Hall Institute of Medical Research
425:2002 β Paul Harris Fellow of The Rotary Foundation
550:Peter Klinken appointed new Chief Scientist of WA
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721:Surprise βThank youβ for Professor Peter Klinken
356:While writing his PhD thesis, Klinken taught at
212:(AC) in the June 2017 Queen's Birthday Honours.
449:2017 β Companion of the Order of Australia (AC)
571:, 2017 Queen's Birthday Honours, www.gg.gov.au
862:Science Statement β growing Western Australia
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454:Professional responsibilities and engagements
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273:about living persons that is unsourced or
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983:People educated at Aquinas College, Perth
846:Learn how and when to remove this message
344:Learn how and when to remove this message
697:Molecular Endocrinology and Pharmacology
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625:, Australian Cancer Research Foundation
581:Graduates earn Queen's Birthday Honours
958:University of Western Australia alumni
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822:or harmful. Please help to
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164:Aquinas College, Perth
963:Australian scientists
735:, www.dpc.wa.gov.au
733:Chief Scientist of WA
610:20 March 2017 at the
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467:Research publications
358:Scotch College, Perth
208:. He was appointed a
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379:Royal Perth Hospital
271:Contentious material
709:QEII Medical Centre
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188:Svend Peter Klinken
132:Svend Peter Klinken
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604:2014 Annual Report
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803:references
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646:26 January
537:References
414:Dave Kelly
304:newspapers
171:Alma mater
155:Australian
138:1953-07-30
101:Dave Kelly
661:Home page
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160:Education
147:Singapore
77:Incumbent
25:Professor
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