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London Declaration on Neglected Tropical Diseases

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control of Guinea worm disease; by 2018, it was eliminated in 19 of 21 countries. As the London Declaration programme ended, only 15 cases were recorded globally. Lymphatic filariasis was eliminated as public health problems in 16 countries, trachoma in 10 countries, and onchocerciasis in four. Annual cases of African trypanosomiasis were reduced from more than 7000 in 2012 to fewer than 1000 in 2018; the number surpassed the projected 2000 cases by 2020. Cases of leprosy has been reduced to 1% in a year.
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The programme did not meet complete success, but millions of lives were saved, the burden of the infections was reduced, and 42 countries eliminated at least one disease. An estimated 500 million people became free from treatments against one or more diseases. One of the biggest successes was the
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The annual progress reports on the London Declaration are reported by the organisation, Uniting to Combat Neglected Tropical Diseases. These reports celebrated progress and identified the issues in achieving the aims of the declaration. In 2017, the Uniting to Combat NTDs received the
727: 392:: An international non-profit organization based in Argentina to fight against Chagas disease and STHs. It contributed US$ 5 million for project expansion and program enhancement for selected sites in the Americas and Africa. 487:, academic institutes and companies. As the programme was launched, the governments of Brazil, Tanzania, Bangladesh and Mozambique announced political and financial commitment to the implementation of the programme. 353:
supports blindness prevention through its SightFirst programme to fight blinding trachoma. The SightFirst has allocated over US$ 11 million in 10 countries for eye surgeries, medical training, distribution of
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tablets each year to fight soil-transmitted helminthiasis. Further it will continue to provide 600 million tablets albendazole per year for lymphatic filariasis as long as necessary until the disease is
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company works for the prevention, diagnosis and treatment of all major neglected diseases. It provides innovative technologies, drug compounds and scientific expertise, academic research and
735: 207:: A division of Germany's pharmaceutical company supports the fight against Chagas disease and African sleeping sickness. The company will specifically make their products 835: 376:
for schistosomiasis indefinitely. It will increase its annual donation from 25 million tablets at present to 250 million tablets (worth US$ 23 million per year).
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10 neglected diseases by 2020 by providing more than US$ 785 million to support research and development. These diseases are most rampant in the
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Bill & Melinda Gates Foundation: The foundation has put up a 5-year US$ 363 million commitment, the largest funding for the project.
55: 786: 926:
Hopkins, Donald R.; Ruiz-Tiben, Ernesto; Eberhard, Mark L.; Weiss, Adam; Withers, P. Craig; Roy, Sharon L.; Sienko, Dean G. (2018).
515:. The next year, WHO formally adopted the day to commemorate the launch of both the first NTD road map and the London Declaration. 461: 259: 757: 471: 331:: An American multinational medical and consumer packaged goods manufacturer will work through its collaborative project 47: 27: 1204: 500:
of "Most medication donated in 24 hours (multiple venues)" for donating 207,169,292 doses of drugs within 24 hours.
320:: A London-based multinational pharmaceutical and consumer healthcare company headquartered will donate 400 million 59: 144: 556:
Accelerating Work to Overcome the Global Impact of Neglected Tropical Diseases – A Roadmap for Implementation
1148:"World NTD Day 2022 and a new Kigali Declaration to galvanise commitment to end neglected tropical diseases" 484: 97:
This declaration was the largest coordinated effort to date in health issues and it aimed to eliminate or
787:"Progress in Combating Neglected Tropical Diseases (NTDs): U.S. and Global Efforts from FY2006 to FY2015" 114: 83: 39: 464:
will continue support to over 20 countries and the U.S. Congress had appropriated $ 89 million to USAID.
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will implement the African Programme for Onchocerciasis Control to completely control river blindness.
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in the dissemination of drugs and providing health education. It will extend its existing donation of
1234: 342: 194: 35: 424:: A New York-based American multinational pharmaceutical corporation will continue its donation of 198: 253: 132: 51: 332: 152: 554: 497: 296:(up to 2.2 billion 100 mg tablets) free of charge to WHO to combat lymphatic filariasis. 628:
Cohen, Joshua P.; Silva, Lisseth; Cohen, Alisa; Awatin, Josephine; Sturgeon, Robert (2016).
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that discovers, develops and commercializes therapeutics will donate 445,000 vials of its
239: 124: 63: 8: 176: 98: 1174: 1147: 1123: 1088: 1064: 1031: 1012: 960: 927: 703: 668: 293: 233: 102: 1000: 903: 886: 1179: 1128: 1110: 1069: 1051: 1016: 1004: 965: 947: 908: 708: 690: 649: 728:"Private and Public Partners Unite to Combat 10 Neglected Tropical Diseases by 2020" 645: 314:
over five years (equivalent to $ 8 million) for treatment of visceral leishmaniasis.
1169: 1159: 1118: 1100: 1059: 1043: 996: 955: 939: 898: 698: 680: 641: 382:: An American pharmaceutical company will run Mectizan Donation Program to provide 366:. It has also announced US$ 6.9 million funding to support the Government of China. 303: 229: 184: 836:"Uniting to Combat NTDs program tackles infectious diseases with new world record" 765: 575:"WHO roadmap inspires unprecedented support to defeat neglected tropical diseases" 1105: 317: 299: 285: 279: 140: 1164: 685: 379: 311: 156: 148: 120: 1223: 1114: 1055: 1047: 951: 694: 529: 512: 243: 216: 87: 24: 1183: 1132: 1073: 1008: 984: 969: 912: 811: 712: 653: 629: 443: 425: 373: 359: 346: 275: 119:
The rather ambitious commitment is to eradicate or prevent transmission of
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Elphick-Pooley, Thoko; Engels, Dirk; Uniting to Combat NTDs (2022-01-28).
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Hotez, Peter J.; Aksoy, Serap; Brindley, Paul J.; Kamhawi, Shaden (2020).
943: 451: 447: 411: 399: 336: 321: 215:, the drugs of choice for the disease respectively, doubly accessible in 190: 180: 524: 467: 407: 389: 383: 372:: A German chemical and pharmaceutical company will continue to donate 369: 363: 307: 266:): A global research and development organisation with headquarters at 208: 91: 75: 67: 43: 630:"Progress Report on Neglected Tropical Disease Drug Donation Programs" 1199: 355: 725: 395: 350: 136: 79: 1036:
Transactions of the Royal Society of Tropical Medicine and Hygiene
339:(200 million tablets per year) for soil-transmitted helminthiasis. 860: 734:. Press Room, Bill & Melinda Gates Foundation. Archived from 415: 212: 128: 887:"Neglected tropical diseases: ending the neglect of populations" 764:. Uniting to Combat Neglected Tropical Diseases. Archived from 435: 431: 421: 267: 220: 71: 31: 925: 605:"Research-based pharma pledges on neglected tropical diseases" 669:"Neglected Tropical Diseases: Epidemiology and Global Burden" 439: 403: 289: 204: 1214: 406:
will extend its commitment to provide multi-drug therapy (
1086: 985:"New declaration on neglected tropical diseases endorsed" 288:: A Japanese pharmaceutical company with headquarters at 270:
will actively work for development of new drugs (such as
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The original endorsers with their basic strategies were:
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Bill & Melinda Gates Foundation (30 January 2012).
94:, Co-Chair of the Bill & Melinda Gates Foundation. 86:
to launch this project. The meeting was spearheaded by
1032:"A road map for neglected tropical diseases 2021-2030" 1030:
Malecela, Mwelecele N.; Ducker, Camilla (2021-01-28).
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multinational pharmaceutical company headquartered in
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London Centre for Neglected Tropical Disease Research
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The American Journal of Tropical Medicine and Hygiene
627: 581:. World Health Organization, Geneva. Archived from 667:Mitra, Amal K.; Mawson, Anthony R. (2017-08-05). 602: 535:Kigali Declaration on Neglected Tropical Diseases 511:announced that it will observe 30 January as the 483:There were 71 endorsing organisations, including 38:roadmap to eradicate or prevent transmission for 21:London Declaration on Neglected Tropical Diseases 1221: 928:"Dracunculiasis Eradication: Are We There Yet?" 562:. Geneva: WHO Press, World Health Organization. 1029: 861:"Uniting to Combat NTDs programme sets record" 402:multinational pharmaceutical company based in 108: 386:for river blindness and lymphatic filariasis. 812:"Progress Reports of the London Declaration" 552: 490: 105:of the world and affect 1.4 billion people. 666: 884: 428:for blinding trachoma until at least 2020. 42:by the year 2020. Officials from WHO, the 1173: 1163: 1122: 1104: 1063: 959: 902: 702: 684: 250:The Children's Investment Fund Foundation 758:"Endorsements (endorsing organizations)" 673:Tropical Medicine and Infectious Disease 1089:"World neglected tropical diseases day" 260:Drugs for Neglected Diseases Initiative 179:: A US-based global pharmaceutical and 82:participated in a joint meeting at the 1222: 54:, and government representatives from 982: 603:The Pharma Letter (31 January 2012). 442:will extend its existing donation of 16:Global disease eradication programme 719: 596: 572: 472:international financial institution 223:, where the diseases are prevalent. 167: 48:Bill & Melinda Gates Foundation 13: 1210:NTDs at Helen Keller International 566: 478: 14: 1246: 1193: 1093:PLOS Neglected Tropical Diseases 205:Bayer HealthCare Pharmaceuticals 1139: 1080: 1023: 976: 919: 878: 853: 828: 756:Uniting to Combat NTDs (2012). 646:10.1016/j.clinthera.2016.02.031 507:In 2019, the Government of the 454:for treating sleeping sickness. 162: 90:, Director-General of WHO, and 30:launched on 30 January 2012 in 1152:Infectious Diseases of Poverty 804: 779: 749: 660: 621: 546: 246:-based pharmaceutical company. 145:soil-transmitted helminthiasis 1: 1001:10.1016/S0140-6736(22)01237-5 904:10.1016/S0140-6736(22)00161-1 540: 103:economically deprived regions 28:disease eradication programme 1106:10.1371/journal.pntd.0007999 462:US federal government agency 380:Merck Sharp & Dohme, MSD 7: 983:Burki, Talha (2022-07-02). 518: 115:Neglected tropical diseases 109:Neglected tropical diseases 84:Royal College of Physicians 40:neglected tropical diseases 10: 1251: 1165:10.1186/s40249-021-00932-2 686:10.3390/tropicalmed2030036 553:Crompton DWT, ed. (2012). 112: 885:The Lancet (2022-01-29). 491:Progress and achievements 343:Lions Clubs International 133:African sleeping sickness 50:, the world's 13 leading 36:World Health Organization 34:. It was inspired by the 201:headquartered in London. 52:pharmaceutical companies 762:unitingtocombatntds.org 573:WHO (3 February 2012). 418:) to eradicate leprosy. 292:manufacture and supply 254:charitable organisation 1048:10.1093/trstmh/trab002 840:Guinness World Records 816:Uniting to Combat NTDs 791:www.everycrsreport.com 333:Children Without Worms 153:visceral leishmaniasis 944:10.4269/ajtmh.18-0204 634:Clinical Therapeutics 498:Guinness World Record 329:Johnson & Johnson 509:United Arab Emirates 240:Bristol-Myers Squibb 193:: A British-Swedish 125:lymphatic filariasis 64:United Arab Emirates 732:gatesfoundation.org 609:thepharmaletter.com 197:pharmaceutical and 121:Guinea worm disease 294:Diethylcarbamazine 234:medical technology 1230:Tropical diseases 364:sanitary services 304:biopharmaceutical 199:biologics company 139:; and to control 1242: 1235:Health campaigns 1200:Official website 1188: 1187: 1177: 1167: 1143: 1137: 1136: 1126: 1108: 1084: 1078: 1077: 1067: 1027: 1021: 1020: 980: 974: 973: 963: 923: 917: 916: 906: 882: 876: 875: 873: 872: 857: 851: 850: 848: 847: 832: 826: 825: 823: 822: 808: 802: 801: 799: 798: 783: 777: 776: 774: 773: 753: 747: 746: 744: 743: 738:on 14 March 2013 723: 717: 716: 706: 688: 664: 658: 657: 640:(5): 1193–1204. 625: 619: 618: 616: 615: 600: 594: 593: 591: 590: 585:on April 7, 2014 570: 564: 563: 561: 550: 230:Becton Dickinson 185:health education 168:Initial partners 1250: 1249: 1245: 1244: 1243: 1241: 1240: 1239: 1220: 1219: 1205:End the Neglect 1196: 1191: 1144: 1140: 1099:(1): e0007999. 1085: 1081: 1028: 1024: 981: 977: 924: 920: 883: 879: 870: 868: 859: 858: 854: 845: 843: 834: 833: 829: 820: 818: 810: 809: 805: 796: 794: 785: 784: 780: 771: 769: 754: 750: 741: 739: 724: 720: 665: 661: 626: 622: 613: 611: 601: 597: 588: 586: 571: 567: 559: 551: 547: 543: 521: 493: 481: 479:Other endorsers 318:GlaxoSmithKline 300:Gilead Sciences 280:clinical trials 170: 165: 157:river blindness 141:schistosomiasis 117: 111: 17: 12: 11: 5: 1248: 1238: 1237: 1232: 1218: 1217: 1212: 1207: 1202: 1195: 1194:External links 1192: 1190: 1189: 1138: 1079: 1042:(2): 121–123. 1022: 975: 938:(2): 388–395. 918: 897:(10323): 411. 877: 852: 827: 803: 778: 748: 718: 659: 620: 595: 565: 544: 542: 539: 538: 537: 532: 527: 520: 517: 492: 489: 480: 477: 476: 475: 465: 455: 429: 419: 393: 387: 377: 367: 340: 326: 315: 297: 283: 278:) and perform 257: 247: 237: 232:: An American 227: 224: 202: 188: 169: 166: 164: 161: 149:Chagas disease 113:Main article: 110: 107: 15: 9: 6: 4: 3: 2: 1247: 1236: 1233: 1231: 1228: 1227: 1225: 1216: 1213: 1211: 1208: 1206: 1203: 1201: 1198: 1197: 1185: 1181: 1176: 1171: 1166: 1161: 1157: 1153: 1149: 1142: 1134: 1130: 1125: 1120: 1116: 1112: 1107: 1102: 1098: 1094: 1090: 1083: 1075: 1071: 1066: 1061: 1057: 1053: 1049: 1045: 1041: 1037: 1033: 1026: 1018: 1014: 1010: 1006: 1002: 998: 995:(10345): 15. 994: 990: 986: 979: 971: 967: 962: 957: 953: 949: 945: 941: 937: 933: 929: 922: 914: 910: 905: 900: 896: 892: 888: 881: 866: 865:BusinessGhana 862: 856: 841: 837: 831: 817: 813: 807: 792: 788: 782: 768:on 2013-05-25 767: 763: 759: 752: 737: 733: 729: 722: 714: 710: 705: 700: 696: 692: 687: 682: 678: 674: 670: 663: 655: 651: 647: 643: 639: 635: 631: 624: 610: 606: 599: 584: 580: 576: 569: 558: 557: 549: 545: 536: 533: 531: 530:Helminthiasis 528: 526: 523: 522: 516: 514: 513:World NTD Day 510: 505: 501: 499: 488: 486: 473: 469: 466: 463: 459: 456: 453: 449: 445: 441: 437: 433: 430: 427: 423: 420: 417: 413: 409: 405: 401: 397: 394: 391: 388: 385: 381: 378: 375: 371: 368: 365: 361: 357: 352: 348: 344: 341: 338: 334: 330: 327: 323: 319: 316: 313: 309: 305: 301: 298: 295: 291: 287: 284: 281: 277: 273: 269: 265: 261: 258: 255: 251: 248: 245: 241: 238: 235: 231: 228: 225: 222: 218: 217:South America 214: 210: 206: 203: 200: 196: 195:multinational 192: 189: 186: 182: 178: 175: 174: 173: 160: 158: 154: 150: 146: 142: 138: 135:and blinding 134: 130: 126: 122: 116: 106: 104: 100: 95: 93: 89: 88:Margaret Chan 85: 81: 77: 73: 69: 65: 61: 57: 53: 49: 45: 41: 37: 33: 29: 26: 25:collaborative 22: 1155: 1151: 1141: 1096: 1092: 1082: 1039: 1035: 1025: 992: 988: 978: 935: 931: 921: 894: 890: 880: 869:. 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Index

collaborative
disease eradication programme
London
World Health Organization
neglected tropical diseases
World Bank
Bill & Melinda Gates Foundation
pharmaceutical companies
US
UK
United Arab Emirates
Bangladesh
Brazil
Mozambique
Tanzania
Royal College of Physicians
Margaret Chan
Bill Gates
control
economically deprived regions
Neglected tropical diseases
Guinea worm disease
lymphatic filariasis
leprosy
African sleeping sickness
trachoma
schistosomiasis
soil-transmitted helminthiasis
Chagas disease
visceral leishmaniasis

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