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Trachoma

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227: 51: 691:. As of June 2022, 125 million individuals live in trachoma endemic areas and are at risk of trachoma-related blindness, and the disease is a public health problem in 42 countries. Of these, Africa is considered the worst affected area, with over 85% of all known active cases of trachoma. Within the continent, South Sudan and Ethiopia have the highest prevalence. In many of these communities, women are three times more likely than men to be blinded by the disease, likely due to their roles as caregivers in the family. Australia is the only developed country that has trachoma. In 2008, trachoma was found in half of Australia's very remote communities. 585: 704:
seen as impractical; the WHO definition of "eliminated as a public-health problem" means less than 5% of children have any symptoms, and less than 0.1% of adults have vision loss. Having already donated more doses (about 700 million since 2002) of the drug than it has sold during the same time period, the drug company Pfizer has agreed to donate azithromycin until 2025, if necessary, for elimination of the disease. The campaign unexpectedly found distribution of azithromycin to very poor children reduced their early death rate by up to 25%.
509:. Azithromycin can be used in children from the age of six months and in pregnancy. As a community-based antibiotic treatment, some evidence suggests that oral azithromycin was more effective than topical tetracycline, but no consistent evidence supported either oral or topical antibiotics as being more effective. Antibiotic treatment reduces the risk of active trachoma in individuals infected with chlamydial trachomatis. 700:
that lays out actions and milestones to achieve global elimination of blinding trachoma by 2020. The program recommends the SAFE protocol for blindness prevention: Surgery for trichiasis, Antibiotics to clear infection, Facial cleanliness, and Environmental improvement to reduce transmission. This includes sanitation infrastructure to reduce the open presence of human feces that can breed flies.
724:(1798–1815), trachoma was rampant in the army barracks of Europe and spread to those living in towns as troops returned home. Stringent control measures were introduced, and by the early 20th century, trachoma was essentially controlled in Europe, although cases were reported until the 1950s. Today, most victims of trachoma live in underdeveloped and poverty-stricken countries in 770:
Due to improved sanitation and overall living conditions, trachoma virtually disappeared from the industrialized world by the 1950s, though it continues to plague the developing world to this day. Epidemiological studies were conducted in 1956–1963 by the Trachoma Control Pilot Project in India under
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For individuals with trichiasis, a bilamellar tarsal rotation procedure is warranted to direct the lashes away from the globe. Evidence suggests that use of a lid clamp and absorbable sutures would result in reduced lid contour abnormalities and granuloma formulation after surgery. Early intervention
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A systematic review examining the effectiveness of environmental sanitary measures on the prevalence of active trachoma in endemic areas showed that use of insecticide spray resulted in significant reductions of trachoma and fly density in some studies. Health education also resulted in reductions of
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In the United States, the Centers for Disease Control says, "No national or international surveillance exists. Blindness due to trachoma has been eliminated from the United States. The last cases were found among Native American populations and in Appalachia, and those in the boxing, wrestling, and
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In 1996, the WHO launched its Alliance for the Global Elimination of Trachoma by 2020, and in 2006, the WHO officially set 2020 as the target to eliminate trachoma as a public-health problem. The International Coalition for Trachoma Control has produced maps and a strategic plan called 2020 INSight
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WHO Guidelines recommend that a region should receive community-based, mass antibiotic treatment when the prevalence of active trachoma among one- to nine-year-old children is greater than 10%. Subsequent annual treatment should be administered for three years, at which time the prevalence should be
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The later structural changes of trachoma are referred to as "cicatricial trachoma". These include scarring under the eyelid (tarsal conjunctiva) that leads to distortion of the eyelid with buckling of the lid (tarsus) so the lashes rub against the eye (trichiasis). This can lead to corneal opacities
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can reduce the rates of active trachoma, especially intense trachoma. If an individual is already infected, washing one's face is encouraged, especially a child, to prevent reinfection. Some evidence shows that washing the face combined with topical tetracycline might be more effective in reducing
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As of 2018, Cambodia, Ghana, Iran, Laos, Mexico, Nepal, Morocco, and Oman have been certified as having eliminated trachoma as a public-health problem; China, Gambia, Iran, Iraq, and Myanmar make that claim, but have not sought certification. Eradication of the bacterium that causes the disease is
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The conjunctival inflammation is called "active trachoma" and is usually seen in children, especially those in preschool. It is characterized by white lumps in the undersurface of the upper eyelid (conjunctival follicles or lymphoid germinal centres) and by nonspecific inflammation and thickening,
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The economic burden of trachoma is huge, particularly with regard to covering treatment costs and productivity losses as a result of increased visual impairment, and in some cases, permanent blindness. The global estimated cost of trachoma is reported between $ US2.9 and 5.3 billion each year. By
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Globally, about 80 million people have an active infection. In some areas, infections may be present in as many as 60–90% of children. Among adults, it more commonly affects women than men – likely due to their closer contact with children. The disease is the cause of decreased vision in 2.2
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The bacteria that cause the disease can be spread by both direct and indirect contact with an affected person's eyes or nose. Indirect contact includes through clothing or flies that have come into contact with an affected person's eyes or nose. Children spread the disease more often than adults.
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Blinding endemic trachoma occurs in areas with poor personal and family hygiene. Many factors are indirectly linked to the presence of trachoma including lack of water, absence of latrines or toilets, poverty in general, flies, close proximity to cattle, and crowding. The final common pathway,
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to decrease the number of people infected with the bacterium. This may include treating, all at once, whole groups of people in whom the disease is known to be common. Washing, by itself, is not enough to prevent disease, but may be useful with other measures. Treatment options include oral
472:. These changes pose numerous challenges for implementation. These environmental changes are likely to ultimately affect the transmission of ocular infection by means of lack of facial cleanliness. Particular attention is required for environmental factors that limit clean faces. 775:
This potentially blinding disease remains endemic in the poorest regions of Africa, Asia, and the Middle East and in some parts of Latin America and Australia. Currently, 8 million people are visually impaired as a result of trachoma, and 41 million have an active infection.
351:(the inward turning of the eyelids), which may result in blindness due to damage to the cornea. Children are the most susceptible to infection due to their tendency to get dirty easily, but the blinding effects or more severe symptoms are often not felt until adulthood. 779:
Of the 54 countries that the WHO cited as still having blinding trachoma occurring, Australia is the only developed country—Australian Aboriginal people who live in remote communities with inadequate sanitation are still blinded by this infectious eye disease.
347:(inanimate objects that carry infectious agents), such as towels and/or washcloths, that have had similar contact with these secretions. Flies can also be a route of mechanical transmission. Untreated, repeated trachoma infections result in 740:
sawmill industries (prolonged exposure to combinations of sweat and sawdust often led to the disease). In the late 19th and early 20th centuries, trachoma was the main reason for an immigrant coming through Ellis Island to be deported."
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Its presence was also recorded in ancient China and Mesopotamia. Trachoma became a problem as people moved into crowded settlements or towns where hygiene was poor. It became a particular problem in Europe in the 19th century. After the
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Children with visible nasal discharge, discharge from the eyes, or flies on their faces are at least twice as likely to have active trachoma as children with clean faces. Intensive community-based health education programs to promote
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million people, of whom 1.2 million are completely blind. Trachoma is a public health problem in 42 countries across Africa, Asia, the Middle East, and Central and South America. There are 136.9 million people at risk. It results in
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As of 2011, about 21 million people are actively affected by trachoma, with around 2.2 million people being permanently blind or have severe visual impairment from trachoma. An additional 7.3 million people are reported to have
505:(1% eye ointment twice a day for six weeks). Azithromycin is preferred because it is used as a single oral dose. Although it is expensive, it is generally used as part of the international donation program organized by 549:
severe trachoma compared to topical tetracycline alone. The same trial found no statistical benefit of eye washing alone or in combination with tetracycline eye drops in reducing follicular trachoma amongst children.
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though, seems to be the presence of dirty faces in children, facilitating the frequent exchange of infected ocular discharge from one child's face to another. Most transmission of trachoma occurs within the family.
1285: 2637: 2622: 206:. Azithromycin is preferred because it can be used as a single oral dose. After scarring of the eyelid has occurred, surgery may be required to correct the position of the eyelashes and prevent blindness. 246:". Blinding endemic trachoma results from multiple episodes of reinfection that maintains the intense inflammation in the conjunctiva. Without reinfection, the inflammation gradually subsides. 2910: 468:
Environmental improvement: Modifications in water use, fly control, latrine use, health education, and proximity to domesticated animals have all been proposed to reduce transmission of
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Most commonly, children with active trachoma do not present with symptoms, as the low-grade irritation and ocular discharge is just accepted as normal, but further symptoms may include:
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Trachomatous inflammation, intense (TI)—Papillary hypertrophy and inflammatory thickening of the upper tarsal conjunctiva obscuring more than half the deep tarsal vessels
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Reacher M, Foster A, Huber J. "Trichiasis Surgery for Trachoma. The Bilamellar Tarsal Rotation Procedure." 1993; World Health Organization, Geneva: WHO/PBL/93.29.
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Mackern-Oberti JP, Motrich RN, Breser MA, Sánchez LR, Cuffini C, Rivero VE (2013). "Chlamydia trachomatis infection of the male genital tract: An update".
258:(limbal follicles). Active trachoma can often be irritating and have a watery discharge. Bacterial secondary infection may occur and cause a discharge of 2896: 2309:"Removing The Blinding Curse Of The Mountains: How Dr. McMullen, Of The Public Health Service Is Organizing The War Against Trachoma In The Appalachians" 743:
In 1913, President Woodrow Wilson signed an act designating funds for the eradication of the disease. Immigrants who attempted to enter the U.S. through
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reassessed. Annual treatment should continue until the prevalence drops below 5%. At lower prevalences, antibiotic treatment should be family-based.
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The World Health Organization recommends a simplified grading system for trachoma. The Simplified WHO Grading System is summarized below:
278:). In addition, blood vessels and scar tissue can invade the upper cornea (pannus). Resolved limbal follicles may leave small gaps in the 861: 4886: 2567: 2255: 2065: 2580: 2120: 2383: 2094: 5159: 3347: 940: 5115: 4355: 4350: 4175: 76: 1643:"Preventive chemotherapy: tools for improving the quality of reported data and information: a field manual for implementation" 1269: 5185: 4215: 827:
including the cost for trichiasis treatment, the estimated overall cost for the disease increases to about $ US 8 billion.
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Trachomatous trichiasis (TT)—At least one ingrown eyelash touching the globe, or evidence of epilation (eyelash removal)
231: 1669:"How much is not enough? A community randomized trial of a Water and Health Education programme for Trachoma and Ocular 4909: 4323: 4210: 3777: 2146: 1440: 772: 747:, New York, had to be checked for trachoma. During this time, treatment for the disease was by topical application of 4078: 3938: 2741: 855: 425:
Trachomatous inflammation, follicular (TF)—Five or more follicles of >0.5 mm on the upper tarsal conjunctiva
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The bacterium has an incubation period of 5 to 10 days, after which the affected individual experiences symptoms of
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The disease is one of the earliest known eye afflictions, having been identified in Egypt as early as 15 BCE.
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active trachoma when implemented. Improved water supply did not result in a reduction of trachoma incidence.
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Poor sanitation, crowded living conditions, and not enough clean water and toilets also increase spread.
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India's Health and Family Welfare Minister JP Nadda declared India free of infective trachoma in 2017.
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in the 20th century (Australia being a notable exception), this disease persists in many parts of the
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Evans JR, Solomon AW, Kumar R, Perez Á, Singh BP, Srivastava RM, Harding-Esch E (26 September 2019).
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Swanner Yann A. Meunier; with contributions from Michael Hole, Takudzwa Shumba & B.J. (2014).
456:, particularly in communities without adequate access to water and sanitation. It is grouped as a 5258: 5028: 4936: 4534: 4288: 4088: 3608: 3601: 3288: 2831: 275: 1667:
Abdou A, Baarè I, Kadri B, Moussa F, Munoz BE, Nassirou B, Opong E, Riverson J, West SK (2009).
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Gupta, UC and Preobragenski, W (1964), Trachoma in India—Endemicity and Epidemiological study,
756: 290: 182:. Untreated, repeated trachoma infections can result in a form of permanent blindness when the 2692: 2308: 845: 339:, serotypes (serovars) A, B, and C. It is spread by direct contact with eye, nose, and throat 5311: 4746: 4422: 3256: 3187: 2252: 335: 162: 97: 5045: 4390: 2069: 1165: 5055: 4519: 4105: 4100: 4058: 3873: 3789: 3235: 3228: 3178: 3058: 3026: 2124: 211: 193:
Efforts to prevent the disease include improving access to clean water and treatment with
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Allen SK, Semba RD (2002). "The trachoma menace in the United States, 1897–1960".
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Disease Listing, Trachoma, Technical Information | CDC Bacterial, Mycotic Diseases
2015:"Contribution of Sex-linked Biology and Gender Roles to Disparities with Trachoma" 174:. This roughening can lead to pain in the eyes, breakdown of the outer surface or 5023: 4633: 4597: 4561: 4180: 4005: 3992: 3926: 3883: 3801: 3613: 3545: 3465: 3450: 3313: 2997: 2949: 2877: 2836: 2657: 2387: 2313: 2259: 1912: 1609: 1353: 752: 721: 449: 437: 250:
often associated with papillae. Follicles may also appear at the junction of the
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8 billion of economic losses a year. It belongs to a group of diseases known as
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Mariotti SP (November 2004). "New steps toward eliminating blinding trachoma".
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Infectious disease that causes a roughening of the inner surface of the eyelids
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Environmental change to increase access to clean water and improved sanitation
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Trachoma: A Blinding Scourge from the Bronze Age to the Twenty-first Century
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Fenwick A (March 2012). "The global burden of neglected tropical diseases".
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is beneficial as the rate of recurrence is higher in more advanced disease.
4648: 4476: 3857: 3772: 3680: 3558: 3553: 3498: 3493: 3219: 3038: 2872: 2783: 2538: 2491: 2438: 2367: 2293: 2121:"WHO | Blinding trachoma: Progress towards global elimination by 2020" 2048: 2030: 1958: 1892: 1843: 1760: 1706: 1628: 1528: 1486: 1414: 1369: 1231: 1148: 1110: 1056: 1016: 847:
Tropical diseases: a practical guide for medical practitioners and students
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McCallan in 1908 divided the clinical course of trachoma into four stages:
203: 199: 141: 137: 2239: 2095:"Ghana eliminates trachoma, freeing millions from suffering and blindness" 1577: 5280: 5200: 4847: 4798: 4741: 4736: 4693: 4671: 4582: 4573: 4493: 4471: 4283: 4255: 4053: 3921: 3762: 3583: 3460: 3412: 3359: 3171: 3146: 2687: 2149:. International Coalition for Trachoma Control. July 2011. Archived from 1926: 729: 305: 171: 106: 2543:
The American Heritage Dictionary of the English Language, Fourth Edition
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Trachomatous scarring (TS)—Presence of scarring in tarsal conjunctiva.
340: 298: 194: 132: 63: 2726: 2614: 1552:"A simple system for the assessment of trachoma and its complications" 4819: 4793: 4667: 4613: 4601: 4486: 4481: 4466: 4462: 4000: 3698: 3675: 3488: 3435: 3430: 3407: 3193: 2959: 2793: 2698: 1727:"Environmental sanitary interventions for preventing active trachoma" 812: 805: 792: 348: 183: 179: 59: 2381:
Ophthalmology in Malta, C. Savona Ventura, University of Malta, 2003
2342:"The Treatment of Trachoma with Sulfanilamide: A Report of 28 Cases" 5285: 5253: 4932: 4623: 4157: 3960: 3591: 3016: 2975: 2798: 2773: 1435:(24th ed.). Philadelphia: Elsevier Saunders. pp. e326-2. 243: 2068:. Australian Institute of Health and Welfare. 2008. Archived from 1382: 5060: 5018: 4975: 4685: 4628: 4170: 3977: 3908: 3878: 3868: 3475: 2821: 2788: 2778: 266:
and scarring and then to blindness. Linear scars present in the
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Granular conjunctivitis, blinding trachoma, Egyptian ophthalmia
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Thylefors B, Dawson CR, Jones BR, West SK, Taylor HR (1987).
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Crowded living conditions, not enough clean water and toilets
2066:"Eye health in Aboriginal and Torres Strait Islander people" 569:. Surgery may also be necessary to fix eyelid deformities. 4985: 3840: 3402: 2984: 1857:
Burton MJ, Kinteh F, Jallow O, et al. (October 2005).
733: 2599: 1773: 1286:"Trachoma - including symptoms, treatment and prevention" 1193: 1074: 533:
Antibiotics to treat active infection, using azithromycin
259: 2183:"Now in Sight: Success Against an Infection That Blinds" 1549: 1507:
Wright HR, Turner A, Taylor HR (June 2008). "Trachoma".
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physicians examining new immigrants for trachoma in 1910
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Solomon AW, Zondervan M, Kuper H, et al. (2006).
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Transactions of the American Ophthalmological Society
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Ejere HO, Alhassan, MB, Rabiu, M (20 February 2015).
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The most important complication to look out for is a
2604: 2060: 2058: 1807: 4389: 1194:Foster A, Mabey DC, Peeling RW, Solomon AW (2004). 572:Without intervention, trachoma keeps families in a 2466:"Trachoma elimination targets missed in Australia" 1856: 1776:"Trachoma control: a guide for programme managers" 1506: 1455: 1376: 591:for trachoma per 100,000 inhabitants in 2004 448:Although trachoma was eliminated from much of the 5145:London Declaration on Neglected Tropical Diseases 4334:arteritic anterior (AAION or arteritic AION) 2055: 1725:Rabiu M, Alhassan MB, Ejere HO, Evans JR (2012). 536:Facial cleanliness to reduce disease transmission 530:Surgery to correct advanced stages of the disease 5298: 2581:"Preventable Disease Blinds Poor in Third World" 501:(single oral dose of 20 mg/kg) or topical 460:which is a target for preventive chemotherapy. 2012: 1122: 1120: 4894: 3355: 3341: 2904: 2742: 1978: 1976: 391:Appearance of mature follicle & papillae 160:is an infectious disease caused by bacterium 5327:Infectious diseases with eradication efforts 4408:Chronic progressive external ophthalmoplegia 2218:Bulletin of the New York Academy of Medicine 1808:Burton M, Habtamu E, Ho D, Gower EW (2015). 1259: 874:: CS1 maint: multiple names: authors list ( 526:The WHO-recommended SAFE strategy includes: 363: 317:Further ear, nose, and throat complications. 3736:Thygeson's superficial punctate keratopathy 3395: 1311:"Trachoma diseases: Prevention and Control" 1126: 1117: 1070: 1068: 1066: 979:The Cochrane Database of Systematic Reviews 968: 966: 964: 962: 960: 958: 795: 755:reported success in treating trachoma with 343:from affected individuals, or contact with 4901: 4887: 3348: 3334: 2911: 2897: 2749: 2735: 2339: 2271: 1973: 1801: 1677:Tropical Medicine and International Health 927: 925: 923: 921: 919: 917: 915: 913: 911: 909: 907: 905: 49: 3110: 2481: 2357: 2229: 2038: 1882: 1833: 1750: 1696: 1618: 1608: 1567: 1556:Bulletin of the World Health Organization 1404: 1221: 1100: 1030: 1028: 1026: 1006: 903: 901: 899: 897: 895: 893: 891: 889: 887: 885: 463: 411:Sequelae to cicatrisation cause symptoms 3154: 2089: 2087: 1929:, Wright H (December 2014). "Trachoma". 1720: 1718: 1716: 1426: 1424: 1255: 1253: 1251: 1249: 1247: 1245: 1243: 1241: 1160: 1158: 1063: 955: 583: 408:Scars are easily visible as white bands 225: 5160:Malaria Eradication Scientific Alliance 2756: 2463: 2314:The World's Work: A History of Our Time 1814:Cochrane Database of Systematic Reviews 1810:"Interventions for trachoma trichiasis" 1731:Cochrane Database of Systematic Reviews 1635: 1456:Mabey DC, Solomon AW, Foster A (2003). 1430: 1081:Cochrane Database of Systematic Reviews 1034: 843: 5299: 2412: 2207: 2205: 2180: 2176: 2174: 2172: 2170: 2168: 1590: 1335: 1196:"Diagnosis and Assessment of Trachoma" 1023: 882: 864:from the original on 8 September 2017. 4882: 4845: 4241: 3644: 3373: 3329: 2892: 2730: 2453:from the original on 2 December 2013. 2306: 2084: 1713: 1421: 1264:. Centre for Eye Research Australia. 1238: 1155: 521: 417: 221: 5186:National Malaria Eradication Program 4216:Familial exudative vitreoretinopathy 933:"Blinding Trachoma Fact sheet N°382" 773:Indian Council for Medical Research. 593: 397:Disease is cured or is not markable 388:Hyperaemia of palpebral conjunctiva 5150:Global Polio Eradication Initiative 4339:non-arteritic anterior (NAION) 4176:Leber's hereditary optic neuropathy 2431:10.5694/j.1326-5377.2001.tb143622.x 2211: 2202: 2165: 119:Mass treatment, improved sanitation 13: 4910:Eradication of infectious diseases 4211:Persistent tunica vasculosa lentis 2403:, Volume 12, issue 2, pages 39–49. 1788:from the original on 12 July 2008. 1385:Journal of Reproductive Immunology 943:from the original on 14 March 2014 394:Scarring of palpebral conjunctiva 14: 5338: 5249:Mathematical modelling of disease 5040: 3939:Polypoidal choroidal vasculopathy 2600:International Trachoma Initiative 2579:Celia W. Dugger (31 March 2006), 2561: 751:. By the late 1930s, a number of 5116:Bovine spongiform encephalopathy 4044:Central retinal artery occlusion 2590:Photographs of trachoma patients 1925:Taylor HR, Burton MJ, Haddad D, 1863:British Journal of Ophthalmology 1689:10.1111/j.1365-3156.2009.02429.x 493: 5181:Boll Weevil Eradication Program 5155:Global Certification Commission 4049:Branch retinal artery occlusion 3778:Terrien's marginal degeneration 2531: 2506: 2457: 2406: 2401:Indian Journal of Ophthalmology 2393: 2374: 2333: 2300: 2265: 2246: 2139: 2123:. 10 April 2006. Archived from 2113: 2006: 1918: 1899: 1850: 1792: 1767: 1660: 1584: 1543: 1500: 1449: 1329: 1303: 1278: 1129:New England Journal of Medicine 579: 565:and consequent scarring of the 380:Stage 3 (cicatrising trachoma) 377:Stage 2 (established trachoma) 4846: 4079:Bietti's crystalline dystrophy 4039:Central retinal vein occlusion 3768:Pellucid marginal degeneration 2013:Courtright P, West SK (2004). 1826:10.1002/14651858.CD004008.pub3 1743:10.1002/14651858.CD004003.PUB4 1214:10.1128/CMR.17.4.982-1011.2004 1187: 1093:10.1002/14651858.CD003659.pub4 991:10.1002/14651858.CD001860.pub4 837: 694: 479: 1: 4960:Eradication of dracunculiasis 4132:Vitelliform macular dystrophy 4023:Posterior vitreous detachment 3889:Persistent pupillary membrane 2483:10.1016/S2666-5247(22)00294-4 2464:Barksby R (1 December 2022). 2286:10.1016/S0039-6257(02)00340-5 2181:McNeil DG Jr (16 July 2018). 1943:10.1016/s0140-6736(13)62182-0 1781:. World Health Organization. 1521:10.1016/S0140-6736(08)60836-3 1479:10.1016/S0140-6736(03)13914-1 1201:Clinical Microbiology Reviews 830: 763:(who was later to become the 589:Disability-adjusted life year 557:If not treated properly with 488: 443: 374:Stage 1 (incipient trachoma) 4619:Leber's congenital amaurosis 4530:Internuclear ophthalmoplegia 4242: 4221:Vogt-Koyanagi-Harada disease 4206:Persistent fetal vasculature 4137:Leber's congenital amaurosis 3305:Streptobacillus moniliformis 2419:Medical Journal of Australia 2019:Emerging Infectious Diseases 1915:18 July 2008 – 24 March 2009 1610:10.1371/journal.pmed.1001605 1354:10.1016/j.ophtha.2013.11.018 821: 813: 806: 786: 552: 358: 311:Sensitivity to bright lights 242:, or irritation similar to " 172:inner surface of the eyelids 7: 3418:Meibomian gland dysfunction 3064:Louse borne relapsing fever 1984:"Epidemiological situation" 405:Progressive corneal pannus 216:neglected tropical diseases 10: 5343: 4142:Birdshot chorioretinopathy 4116:Central serous retinopathy 3934:Focal choroidal excavation 3807:Corneal neovascularization 3624:Subconjunctival hemorrhage 3374: 3088:Tick borne relapsing fever 1049:10.1016/j.puhe.2011.11.015 975:"Antibiotics for trachoma" 707: 512: 458:neglected tropical disease 383:Stage 4 (healed trachoma) 178:of the eyes, and eventual 20: 5244:Globalization and disease 5236: 5168: 5137: 5128: 5103: 5094:Eradication of rinderpest 5082: 5073: 4999: 4946: 4925: 4916: 4854: 4841: 4812: 4759: 4724: 4684: 4609: 4596: 4547: 4525:Convergence insufficiency 4512: 4453: 4421: 4398: 4368: 4309: 4267: 4254: 4250: 4237: 4166:Primary juvenile glaucoma 4150: 4011:Cytomegalovirus retinitis 3991: 3951: 3907: 3848: 3839: 3689: 3666: 3657: 3653: 3645: 3640: 3582: 3544: 3511: 3474: 3426: 3386: 3382: 3369: 3360:Diseases of the human eye 3296:Fusobacterium polymorphum 3277:Fusobacterium necrophorum 3266: 3243:Capnocytophaga canimorsus 3218: 3145: 3101: 3014: 2957: 2948: 2939: 2865: 2832:African sleeping sickness 2812: 2764: 2678: 2608: 2099:World Health Organization 1988:World Health Organization 1397:10.1016/j.jri.2013.05.002 1174:World Health Organization 937:World Health Organization 791:The term is derived from 364:McCallan's classification 166:. The infection causes a 147: 131: 123: 115: 105: 92: 82: 70: 57: 48: 40: 35: 23:Trachoma (disambiguation) 5276:Tuberculosis elimination 5196:India National PolioPlus 4035:Ocular ischemic syndrome 3250:Porphyromonas gingivalis 3199:Lymphogranuloma venereum 2307:Leupp CD (August 1914). 1433:Goldman's Cecil Medicine 1336:Feibel RM (1 May 2014). 328: 4937:Eradication of smallpox 4535:One and a half syndrome 4289:Foster Kennedy syndrome 3289:Fusobacterium nucleatum 2878:Priority review voucher 2415:"Trachoma in Australia" 2274:Survey of Ophthalmology 1875:10.1136/bjo.2004.062489 276:Carl Ferdinand von Arlt 66:resulting from trachoma 4980:Eradication of malaria 4774:Argyll Robertson pupil 3574:Periorbital cellulitis 3123:Leptospira interrogans 2518:The New Indian Express 2031:10.3201/eid1011.040353 1290:South Australia Health 796: 759:antibiotics. In 1948, 683: 464:Environmental measures 333:Trachoma is caused by 301:(misaligned eyelashes) 235: 5076:agricultural diseases 4747:Scintillating scotoma 4413:Kearns–Sayre syndrome 4356:Toxic and nutritional 4329:posterior (PION) 3812:Kayser–Fleischer ring 3257:Prevotella intermedia 3188:Chlamydia trachomatis 1260:Taylor, Hugh (2008). 587: 336:Chlamydia trachomatis 232:Public Health Service 229: 163:Chlamydia trachomatis 101:spread between people 98:Chlamydia trachomatis 5322:Chlamydia infections 5014:Lymphatic filariasis 4520:Conjugate gaze palsy 4391:Paralytic strabismus 4324:anterior (AION) 4106:Retinitis pigmentosa 4101:Macular degeneration 3874:Intermediate uveitis 3790:Keratoconjunctivitis 3236:Tannerella forsythia 3229:Bacteroides fragilis 3179:Chlamydia pneumoniae 3059:Borrelia recurrentis 3027:Borrelia burgdorferi 1994:on 19 September 2015 720:(1798–1802) and the 314:Increased heart rate 308:in front of the ears 127:Medications, surgery 21:For other uses, see 4990:Eradication of yaws 4825:Childhood blindness 4804:Parinaud's syndrome 4374:Extraocular muscles 4162:Ocular hypertension 4126:Epiretinal membrane 4111:Retinal haemorrhage 3966:Congenital cataract 3282:Lemierre's syndrome 3005:Treponema denticola 2766:Diseases of poverty 2758:Diseases of poverty 2545:. TheFreeDictionary 2340:Thygeson P (1939). 2212:Yew E (June 1980). 1937:(9960): 2142–2152. 1906:Prevention-Trachoma 1673:infection in Niger" 1141:10.1056/NEJMe048205 184:eyelids turn inward 88:Eye pain, blindness 58:Surgical repair of 4351:Leber's hereditary 4018:Retinal detachment 3971:Childhood cataract 3783:Post-LASIK ectasia 3564:Orbital cellulitis 3513:Lacrimal apparatus 3167:Chlamydia psittaci 2993:Treponema carateum 2970:Treponema pallidum 2920:Bacterial diseases 2814:Neglected diseases 2799:Diarrheal diseases 2679:External resources 2585:The New York Times 2470:The Lancet Microbe 2413:Taylor HR (2001). 2386:2007-07-01 at the 2258:2006-04-18 at the 2188:The New York Times 2153:on 8 November 2014 2072:on 28 October 2012 1911:2009-05-15 at the 1591:Stocks ME (2014). 1431:Goldman L (2011). 765:President of Malta 684: 522:Lifestyle measures 418:WHO classification 402:Immature follicle 282:(Herbert's pits). 268:sulcus subtarsalis 236: 222:Signs and symptoms 77:Infectious disease 5317:Tropical diseases 5294: 5293: 5232: 5231: 5208:Polio in Pakistan 5124: 5123: 5069: 5068: 4970:Polio eradication 4876: 4875: 4872: 4871: 4837: 4836: 4833: 4832: 4779:Marcus Gunn pupil 4755: 4754: 4676:Visual impairment 4543: 4542: 4449: 4448: 4436:Fourth-nerve (IV) 4364: 4363: 4301:Optic disc drusen 4233: 4232: 4229: 4228: 3947: 3946: 3835: 3834: 3741:Corneal dystrophy 3636: 3635: 3632: 3631: 3507: 3506: 3323: 3322: 3214: 3213: 3141: 3140: 3137: 3136: 3097: 3096: 2886: 2885: 2724: 2723: 2025:(11): 2012–2016. 1515:(9628): 1945–54. 1271:978-0-9757695-9-1 939:. November 2013. 718:Egyptian Campaign 681: 680: 415: 414: 155: 154: 30:Medical condition 5334: 5214:Every Last Child 5135: 5134: 5111:Ovine rinderpest 5080: 5079: 4923: 4922: 4903: 4896: 4889: 4880: 4879: 4843: 4842: 4607: 4606: 4598:Vision disorders 4557:Refractive error 4499:Brown's syndrome 4455:Other strabismus 4441:Sixth-nerve (VI) 4431:Oculomotor (III) 4403:Ophthalmoparesis 4396: 4395: 4387: 4386: 4378:Binocular vision 4311:Optic neuropathy 4277:optic papillitis 4265: 4264: 4252: 4251: 4239: 4238: 4128:(Macular pucker) 3846: 3845: 3827:Band keratopathy 3664: 3663: 3655: 3654: 3642: 3641: 3569:Orbital lymphoma 3456:Blepharophimosis 3446:Blepharochalasis 3393: 3392: 3384: 3383: 3371: 3370: 3350: 3343: 3336: 3327: 3326: 3152: 3151: 3108: 3107: 3083:Borrelia parkeri 3077:Borrelia duttoni 3071:Borrelia hermsii 3049:Neuroborreliosis 3044:Erythema migrans 3033:Borrelia afzelii 2955: 2954: 2946: 2945: 2913: 2906: 2899: 2890: 2889: 2751: 2744: 2737: 2728: 2727: 2606: 2605: 2568:CDC Disease Info 2555: 2554: 2552: 2550: 2535: 2529: 2528: 2526: 2524: 2510: 2504: 2503: 2485: 2461: 2455: 2454: 2410: 2404: 2397: 2391: 2378: 2372: 2371: 2361: 2337: 2331: 2330: 2328: 2326: 2304: 2298: 2297: 2269: 2263: 2250: 2244: 2243: 2233: 2209: 2200: 2199: 2197: 2195: 2178: 2163: 2162: 2160: 2158: 2143: 2137: 2136: 2134: 2132: 2117: 2111: 2110: 2108: 2106: 2091: 2082: 2081: 2079: 2077: 2062: 2053: 2052: 2042: 2010: 2004: 2003: 2001: 1999: 1990:. Archived from 1980: 1971: 1970: 1922: 1916: 1903: 1897: 1896: 1886: 1854: 1848: 1847: 1837: 1820:(11): CD004008. 1805: 1799: 1796: 1790: 1789: 1787: 1780: 1771: 1765: 1764: 1754: 1722: 1711: 1710: 1700: 1664: 1658: 1657: 1655: 1653: 1639: 1633: 1632: 1622: 1612: 1588: 1582: 1581: 1571: 1547: 1541: 1540: 1504: 1498: 1497: 1495: 1493: 1462: 1453: 1447: 1446: 1428: 1419: 1418: 1408: 1380: 1374: 1373: 1348:(5): 1142–1148. 1333: 1327: 1326: 1324: 1322: 1307: 1301: 1300: 1298: 1296: 1282: 1276: 1275: 1257: 1236: 1235: 1225: 1191: 1185: 1184: 1182: 1180: 1162: 1153: 1152: 1124: 1115: 1114: 1104: 1072: 1061: 1060: 1032: 1021: 1020: 1010: 970: 953: 952: 950: 948: 929: 880: 879: 873: 865: 841: 816: 809: 799: 753:ophthalmologists 674: 668: 662: 656: 650: 644: 636: 630: 624: 618: 612: 606: 600: 594: 574:cycle of poverty 559:oral antibiotics 454:developing world 371: 370: 60:in-turned eyelid 53: 33: 32: 5342: 5341: 5337: 5336: 5335: 5333: 5332: 5331: 5297: 5296: 5295: 5290: 5228: 5164: 5130: 5120: 5099: 5075: 5065: 5001: 4995: 4948: 4942: 4918: 4912: 4907: 4877: 4868: 4850: 4829: 4808: 4751: 4720: 4680: 4634:Color blindness 4600: 4592: 4539: 4513:Other binocular 4508: 4445: 4417: 4380: 4376: 4372: 4360: 4305: 4258: 4246: 4225: 4181:Ocular hypotony 4146: 4006:Chorioretinitis 3987: 3943: 3927:Chorioretinitis 3903: 3884:Rubeosis iridis 3862: 3831: 3802:Corneal opacity 3758:Corneal ectasia 3685: 3649: 3628: 3614:Pseudopterygium 3578: 3540: 3503: 3470: 3466:Ankyloblepharon 3422: 3378: 3365: 3364: 3354: 3324: 3319: 3314:Haverhill fever 3262: 3210: 3133: 3093: 3010: 2950:Spirochaetaceae 2935: 2917: 2887: 2882: 2861: 2847:River blindness 2837:Schistosomiasis 2808: 2760: 2755: 2725: 2720: 2719: 2674: 2673: 2617: 2564: 2559: 2558: 2548: 2546: 2537: 2536: 2532: 2522: 2520: 2512: 2511: 2507: 2462: 2458: 2411: 2407: 2398: 2394: 2388:Wayback Machine 2379: 2375: 2338: 2334: 2324: 2322: 2305: 2301: 2270: 2266: 2260:Wayback Machine 2251: 2247: 2210: 2203: 2193: 2191: 2179: 2166: 2156: 2154: 2145: 2144: 2140: 2130: 2128: 2119: 2118: 2114: 2104: 2102: 2093: 2092: 2085: 2075: 2073: 2064: 2063: 2056: 2011: 2007: 1997: 1995: 1982: 1981: 1974: 1923: 1919: 1913:Wayback Machine 1904: 1900: 1855: 1851: 1806: 1802: 1797: 1793: 1785: 1778: 1772: 1768: 1737:(2): CD004003. 1723: 1714: 1665: 1661: 1651: 1649: 1641: 1640: 1636: 1603:(2): e1001605. 1589: 1585: 1548: 1544: 1505: 1501: 1491: 1489: 1460: 1454: 1450: 1443: 1429: 1422: 1381: 1377: 1334: 1330: 1320: 1318: 1309: 1308: 1304: 1294: 1292: 1284: 1283: 1279: 1272: 1258: 1239: 1208:(4): 982–1011. 1192: 1188: 1178: 1176: 1164: 1163: 1156: 1125: 1118: 1087:(2): CD003659. 1073: 1064: 1033: 1024: 985:(9): CD001860. 971: 956: 946: 944: 931: 930: 883: 867: 866: 858: 842: 838: 833: 824: 789: 722:Napoleonic Wars 710: 697: 682: 676: 672: 670: 666: 664: 660: 658: 654: 652: 648: 646: 642: 638: 634: 632: 628: 626: 622: 620: 616: 614: 610: 608: 604: 602: 598: 582: 555: 524: 515: 496: 491: 482: 466: 450:developed world 446: 438:Corneal opacity 420: 366: 361: 331: 295:Swollen eyelids 224: 31: 26: 17: 12: 11: 5: 5340: 5330: 5329: 5324: 5319: 5314: 5309: 5292: 5291: 5289: 5288: 5283: 5278: 5273: 5272: 5271: 5266: 5256: 5251: 5246: 5240: 5238: 5237:Related topics 5234: 5233: 5230: 5229: 5227: 5226: 5225: 5224: 5221:The Final Inch 5217: 5205: 5204: 5203: 5198: 5190: 5189: 5188: 5183: 5172: 5170: 5166: 5165: 5163: 5162: 5157: 5152: 5147: 5141: 5139: 5132: 5126: 5125: 5122: 5121: 5119: 5118: 5113: 5107: 5105: 5101: 5100: 5098: 5097: 5086: 5084: 5077: 5074:Eradication of 5071: 5070: 5067: 5066: 5064: 5063: 5058: 5053: 5048: 5046:Onchocerciasis 5043: 5038: 5033: 5032: 5031: 5026: 5016: 5011: 5005: 5003: 4997: 4996: 4994: 4993: 4983: 4973: 4963: 4956:Dracunculiasis 4952: 4950: 4944: 4943: 4941: 4940: 4929: 4927: 4920: 4919:human diseases 4917:Eradication of 4914: 4913: 4906: 4905: 4898: 4891: 4883: 4874: 4873: 4870: 4869: 4867: 4866: 4864:Onchocerciasis 4861: 4855: 4852: 4851: 4839: 4838: 4835: 4834: 4831: 4830: 4828: 4827: 4822: 4816: 4814: 4810: 4809: 4807: 4806: 4801: 4796: 4791: 4786: 4781: 4776: 4771: 4765: 4763: 4757: 4756: 4753: 4752: 4750: 4749: 4744: 4739: 4734: 4728: 4726: 4722: 4721: 4719: 4718: 4716:Quadrantanopia 4713: 4712: 4711: 4706: 4701: 4690: 4688: 4682: 4681: 4679: 4678: 4665: 4664: 4663: 4661:Oguchi disease 4653: 4652: 4651: 4646: 4641: 4631: 4626: 4621: 4616: 4610: 4604: 4594: 4593: 4591: 4590: 4585: 4576: 4571: 4570: 4569: 4564: 4553: 4551: 4545: 4544: 4541: 4540: 4538: 4537: 4532: 4527: 4522: 4516: 4514: 4510: 4509: 4507: 4506: 4504:Duane syndrome 4501: 4496: 4491: 4490: 4489: 4484: 4474: 4469: 4459: 4457: 4451: 4450: 4447: 4446: 4444: 4443: 4438: 4433: 4427: 4425: 4419: 4418: 4416: 4415: 4410: 4405: 4399: 4393: 4384: 4366: 4365: 4362: 4361: 4359: 4358: 4353: 4348: 4343: 4342: 4341: 4336: 4331: 4326: 4315: 4313: 4307: 4306: 4304: 4303: 4298: 4293: 4292: 4291: 4281: 4280: 4279: 4272:Optic neuritis 4268: 4262: 4248: 4247: 4235: 4234: 4231: 4230: 4227: 4226: 4224: 4223: 4218: 4213: 4208: 4203: 4201:Phthisis bulbi 4198: 4193: 4188: 4183: 4178: 4173: 4168: 4154: 4152: 4148: 4147: 4145: 4144: 4139: 4134: 4129: 4123: 4118: 4113: 4108: 4103: 4098: 4097: 4096: 4091: 4086: 4084:Coats' disease 4081: 4076: 4074:of prematurity 4071: 4066: 4061: 4051: 4046: 4041: 4032: 4027: 4026: 4025: 4015: 4014: 4013: 4008: 3997: 3995: 3989: 3988: 3986: 3985: 3983:Ectopia lentis 3980: 3975: 3974: 3973: 3968: 3957: 3955: 3949: 3948: 3945: 3944: 3942: 3941: 3936: 3931: 3930: 3929: 3919: 3913: 3911: 3905: 3904: 3902: 3901: 3896: 3891: 3886: 3881: 3876: 3871: 3865: 3863: 3861: 3860: 3855: 3849: 3843: 3841:Vascular tunic 3837: 3836: 3833: 3832: 3830: 3829: 3824: 3819: 3814: 3809: 3804: 3799: 3798: 3797: 3787: 3786: 3785: 3780: 3775: 3770: 3765: 3755: 3754: 3753: 3748: 3738: 3733: 3728: 3727: 3726: 3724:Photokeratitis 3721: 3716: 3711: 3706: 3695: 3693: 3687: 3686: 3684: 3683: 3678: 3672: 3670: 3661: 3651: 3650: 3638: 3637: 3634: 3633: 3630: 3629: 3627: 3626: 3621: 3616: 3611: 3606: 3605: 3604: 3597:Conjunctivitis 3594: 3588: 3586: 3580: 3579: 3577: 3576: 3571: 3566: 3561: 3556: 3550: 3548: 3542: 3541: 3539: 3538: 3533: 3531:Dacryocystitis 3528: 3523: 3521:Dacryoadenitis 3517: 3515: 3509: 3508: 3505: 3504: 3502: 3501: 3496: 3491: 3486: 3480: 3478: 3472: 3471: 3469: 3468: 3463: 3458: 3453: 3448: 3443: 3438: 3433: 3427: 3424: 3423: 3421: 3420: 3415: 3410: 3405: 3399: 3397: 3390: 3380: 3379: 3367: 3366: 3363: 3362: 3356: 3353: 3352: 3345: 3338: 3330: 3321: 3320: 3318: 3317: 3310:Rat-bite fever 3300: 3299: 3292: 3285: 3272: 3270: 3268:Fusobacteriota 3264: 3263: 3261: 3260: 3253: 3246: 3239: 3232: 3224: 3222: 3216: 3215: 3212: 3211: 3209: 3208: 3207: 3206: 3201: 3196: 3183: 3182: 3175: 3162: 3160: 3149: 3143: 3142: 3139: 3138: 3135: 3134: 3132: 3131: 3118: 3116: 3105: 3103:Leptospiraceae 3099: 3098: 3095: 3094: 3092: 3091: 3067: 3054: 3053: 3052: 3051: 3046: 3041: 3022: 3020: 3012: 3011: 3009: 3008: 3001: 2989: 2988: 2987: 2982: 2965: 2963: 2952: 2943: 2937: 2936: 2928:proteobacteria 2916: 2915: 2908: 2901: 2893: 2884: 2883: 2881: 2880: 2875: 2869: 2867: 2863: 2862: 2860: 2859: 2854: 2849: 2844: 2842:Dracunculiasis 2839: 2834: 2829: 2827:Chagas disease 2824: 2818: 2816: 2810: 2809: 2807: 2806: 2801: 2796: 2791: 2786: 2781: 2776: 2770: 2768: 2762: 2761: 2754: 2753: 2746: 2739: 2731: 2722: 2721: 2718: 2717: 2706: 2695: 2683: 2682: 2680: 2676: 2675: 2672: 2671: 2660: 2649: 2634: 2618: 2613: 2612: 2610: 2609:Classification 2603: 2602: 2597: 2595:Trachoma Atlas 2592: 2587: 2576: 2575: 2563: 2562:External links 2560: 2557: 2556: 2530: 2505: 2456: 2425:(7): 371–372. 2405: 2392: 2373: 2332: 2299: 2264: 2245: 2224:(5): 488–510. 2201: 2164: 2138: 2127:on 8 July 2015 2112: 2101:. 13 June 2018 2083: 2054: 2005: 1972: 1917: 1898: 1869:(10): 1282–8. 1849: 1800: 1791: 1766: 1712: 1671:C. trachomatis 1659: 1634: 1583: 1542: 1499: 1448: 1442:978-1437727883 1441: 1420: 1375: 1328: 1315:Heart Diseases 1302: 1277: 1270: 1237: 1186: 1154: 1135:(19): 2004–7. 1116: 1062: 1022: 954: 881: 856: 835: 834: 832: 829: 823: 820: 810:, from τραχύς 788: 785: 761:Vincent Tabone 749:copper sulfate 709: 706: 696: 693: 679: 678: 671: 665: 659: 653: 647: 641: 639: 633: 627: 621: 615: 609: 603: 597: 592: 581: 578: 554: 551: 541: 540: 537: 534: 531: 523: 520: 514: 511: 495: 492: 490: 487: 481: 478: 470:C. trachomatis 465: 462: 445: 442: 419: 416: 413: 412: 409: 406: 403: 399: 398: 395: 392: 389: 385: 384: 381: 378: 375: 365: 362: 360: 357: 330: 327: 319: 318: 315: 312: 309: 302: 296: 293: 240:conjunctivitis 223: 220: 153: 152: 149: 145: 144: 135: 129: 128: 125: 121: 120: 117: 113: 112: 109: 103: 102: 94: 90: 89: 86: 80: 79: 74: 68: 67: 55: 54: 46: 45: 42: 38: 37: 29: 15: 9: 6: 4: 3: 2: 5339: 5328: 5325: 5323: 5320: 5318: 5315: 5313: 5310: 5308: 5305: 5304: 5302: 5287: 5284: 5282: 5279: 5277: 5274: 5270: 5267: 5265: 5262: 5261: 5260: 5257: 5255: 5252: 5250: 5247: 5245: 5242: 5241: 5239: 5235: 5223: 5222: 5218: 5216: 5215: 5211: 5210: 5209: 5206: 5202: 5199: 5197: 5194: 5193: 5191: 5187: 5184: 5182: 5179: 5178: 5177: 5176:United States 5174: 5173: 5171: 5167: 5161: 5158: 5156: 5153: 5151: 5148: 5146: 5143: 5142: 5140: 5136: 5133: 5127: 5117: 5114: 5112: 5109: 5108: 5106: 5102: 5095: 5091: 5088: 5087: 5085: 5081: 5078: 5072: 5062: 5059: 5057: 5054: 5052: 5049: 5047: 5044: 5042: 5039: 5037: 5034: 5030: 5027: 5025: 5022: 5021: 5020: 5017: 5015: 5012: 5010: 5007: 5006: 5004: 4998: 4991: 4987: 4984: 4981: 4977: 4974: 4971: 4967: 4964: 4961: 4957: 4954: 4953: 4951: 4945: 4938: 4934: 4931: 4930: 4928: 4924: 4921: 4915: 4911: 4904: 4899: 4897: 4892: 4890: 4885: 4884: 4881: 4865: 4862: 4860: 4857: 4856: 4853: 4849: 4844: 4840: 4826: 4823: 4821: 4818: 4817: 4815: 4811: 4805: 4802: 4800: 4797: 4795: 4792: 4790: 4787: 4785: 4784:Adie syndrome 4782: 4780: 4777: 4775: 4772: 4770: 4767: 4766: 4764: 4762: 4758: 4748: 4745: 4743: 4740: 4738: 4735: 4733: 4730: 4729: 4727: 4723: 4717: 4714: 4710: 4707: 4705: 4702: 4700: 4697: 4696: 4695: 4692: 4691: 4689: 4687: 4683: 4677: 4673: 4669: 4666: 4662: 4659: 4658: 4657: 4654: 4650: 4647: 4645: 4642: 4640: 4639:Achromatopsia 4637: 4636: 4635: 4632: 4630: 4627: 4625: 4622: 4620: 4617: 4615: 4612: 4611: 4608: 4605: 4603: 4599: 4595: 4589: 4586: 4584: 4580: 4579:Anisometropia 4577: 4575: 4572: 4568: 4565: 4563: 4560: 4559: 4558: 4555: 4554: 4552: 4550: 4546: 4536: 4533: 4531: 4528: 4526: 4523: 4521: 4518: 4517: 4515: 4511: 4505: 4502: 4500: 4497: 4495: 4492: 4488: 4485: 4483: 4480: 4479: 4478: 4475: 4473: 4470: 4468: 4464: 4461: 4460: 4458: 4456: 4452: 4442: 4439: 4437: 4434: 4432: 4429: 4428: 4426: 4424: 4420: 4414: 4411: 4409: 4406: 4404: 4401: 4400: 4397: 4394: 4392: 4388: 4385: 4383: 4382:Accommodation 4379: 4375: 4371: 4367: 4357: 4354: 4352: 4349: 4347: 4344: 4340: 4337: 4335: 4332: 4330: 4327: 4325: 4322: 4321: 4320: 4317: 4316: 4314: 4312: 4308: 4302: 4299: 4297: 4296:Optic atrophy 4294: 4290: 4287: 4286: 4285: 4282: 4278: 4275: 4274: 4273: 4270: 4269: 4266: 4263: 4261: 4257: 4253: 4249: 4245: 4240: 4236: 4222: 4219: 4217: 4214: 4212: 4209: 4207: 4204: 4202: 4199: 4197: 4196:Keratomycosis 4194: 4192: 4191:Globe rupture 4189: 4187: 4184: 4182: 4179: 4177: 4174: 4172: 4169: 4167: 4163: 4159: 4156: 4155: 4153: 4149: 4143: 4140: 4138: 4135: 4133: 4130: 4127: 4124: 4122: 4121:Macular edema 4119: 4117: 4114: 4112: 4109: 4107: 4104: 4102: 4099: 4095: 4092: 4090: 4087: 4085: 4082: 4080: 4077: 4075: 4072: 4070: 4067: 4065: 4062: 4060: 4057: 4056: 4055: 4052: 4050: 4047: 4045: 4042: 4040: 4036: 4033: 4031: 4030:Retinoschisis 4028: 4024: 4021: 4020: 4019: 4016: 4012: 4009: 4007: 4004: 4003: 4002: 3999: 3998: 3996: 3994: 3990: 3984: 3981: 3979: 3976: 3972: 3969: 3967: 3964: 3963: 3962: 3959: 3958: 3956: 3954: 3950: 3940: 3937: 3935: 3932: 3928: 3925: 3924: 3923: 3920: 3918: 3917:Choroideremia 3915: 3914: 3912: 3910: 3906: 3900: 3897: 3895: 3894:Iridodialysis 3892: 3890: 3887: 3885: 3882: 3880: 3877: 3875: 3872: 3870: 3867: 3866: 3864: 3859: 3856: 3854: 3851: 3850: 3847: 3844: 3842: 3838: 3828: 3825: 3823: 3822:Arcus senilis 3820: 3818: 3817:Haab's striae 3815: 3813: 3810: 3808: 3805: 3803: 3800: 3796: 3793: 3792: 3791: 3788: 3784: 3781: 3779: 3776: 3774: 3771: 3769: 3766: 3764: 3761: 3760: 3759: 3756: 3752: 3749: 3747: 3744: 3743: 3742: 3739: 3737: 3734: 3732: 3731:Corneal ulcer 3729: 3725: 3722: 3720: 3717: 3715: 3712: 3710: 3709:acanthamoebic 3707: 3705: 3702: 3701: 3700: 3697: 3696: 3694: 3692: 3688: 3682: 3679: 3677: 3674: 3673: 3671: 3669: 3665: 3662: 3660: 3659:Fibrous tunic 3656: 3652: 3648: 3643: 3639: 3625: 3622: 3620: 3617: 3615: 3612: 3610: 3607: 3603: 3600: 3599: 3598: 3595: 3593: 3590: 3589: 3587: 3585: 3581: 3575: 3572: 3570: 3567: 3565: 3562: 3560: 3557: 3555: 3552: 3551: 3549: 3547: 3543: 3537: 3536:Xerophthalmia 3534: 3532: 3529: 3527: 3524: 3522: 3519: 3518: 3516: 3514: 3510: 3500: 3497: 3495: 3492: 3490: 3487: 3485: 3482: 3481: 3479: 3477: 3473: 3467: 3464: 3462: 3459: 3457: 3454: 3452: 3449: 3447: 3444: 3442: 3441:Lagophthalmos 3439: 3437: 3434: 3432: 3429: 3428: 3425: 3419: 3416: 3414: 3411: 3409: 3406: 3404: 3401: 3400: 3398: 3394: 3391: 3389: 3385: 3381: 3377: 3372: 3368: 3361: 3358: 3357: 3351: 3346: 3344: 3339: 3337: 3332: 3331: 3328: 3315: 3311: 3307: 3306: 3302: 3301: 3298: 3297: 3293: 3291: 3290: 3286: 3283: 3279: 3278: 3274: 3273: 3271: 3269: 3265: 3259: 3258: 3254: 3252: 3251: 3247: 3245: 3244: 3240: 3238: 3237: 3233: 3231: 3230: 3226: 3225: 3223: 3221: 3217: 3205: 3202: 3200: 3197: 3195: 3192: 3191: 3190: 3189: 3185: 3184: 3181: 3180: 3176: 3173: 3169: 3168: 3164: 3163: 3161: 3159: 3158: 3153: 3150: 3148: 3144: 3129: 3128:Leptospirosis 3125: 3124: 3120: 3119: 3117: 3115: 3114: 3109: 3106: 3104: 3100: 3089: 3085: 3084: 3079: 3078: 3073: 3072: 3068: 3065: 3061: 3060: 3056: 3055: 3050: 3047: 3045: 3042: 3040: 3037: 3036: 3035: 3034: 3029: 3028: 3024: 3023: 3021: 3019: 3018: 3013: 3007: 3006: 3002: 2999: 2995: 2994: 2990: 2986: 2983: 2981: 2977: 2974: 2973: 2972: 2971: 2967: 2966: 2964: 2962: 2961: 2956: 2953: 2951: 2947: 2944: 2942: 2941:Spirochaetota 2938: 2933: 2929: 2925: 2924:gram negative 2921: 2914: 2909: 2907: 2902: 2900: 2895: 2894: 2891: 2879: 2876: 2874: 2871: 2870: 2868: 2866:Miscellaneous 2864: 2858: 2855: 2853: 2852:Leishmaniasis 2850: 2848: 2845: 2843: 2840: 2838: 2835: 2833: 2830: 2828: 2825: 2823: 2820: 2819: 2817: 2815: 2811: 2805: 2802: 2800: 2797: 2795: 2792: 2790: 2787: 2785: 2782: 2780: 2777: 2775: 2772: 2771: 2769: 2767: 2763: 2759: 2752: 2747: 2745: 2740: 2738: 2733: 2732: 2729: 2716: 2712: 2711: 2707: 2705: 2701: 2700: 2696: 2694: 2690: 2689: 2685: 2684: 2681: 2677: 2670: 2666: 2665: 2661: 2659: 2655: 2654: 2650: 2648: 2644: 2643: 2639: 2635: 2633: 2629: 2628: 2624: 2620: 2619: 2616: 2611: 2607: 2601: 2598: 2596: 2593: 2591: 2588: 2586: 2582: 2578: 2577: 2574: 2573: 2569: 2566: 2565: 2544: 2540: 2534: 2519: 2515: 2509: 2501: 2497: 2493: 2489: 2484: 2479: 2475: 2471: 2467: 2460: 2452: 2448: 2444: 2440: 2436: 2432: 2428: 2424: 2420: 2416: 2409: 2402: 2396: 2389: 2385: 2382: 2377: 2369: 2365: 2360: 2355: 2351: 2347: 2343: 2336: 2320: 2316: 2315: 2310: 2303: 2295: 2291: 2287: 2283: 2279: 2275: 2268: 2261: 2257: 2254: 2249: 2241: 2237: 2232: 2227: 2223: 2219: 2215: 2208: 2206: 2190: 2189: 2184: 2177: 2175: 2173: 2171: 2169: 2152: 2148: 2142: 2126: 2122: 2116: 2100: 2096: 2090: 2088: 2071: 2067: 2061: 2059: 2050: 2046: 2041: 2036: 2032: 2028: 2024: 2020: 2016: 2009: 1993: 1989: 1985: 1979: 1977: 1968: 1964: 1960: 1956: 1952: 1948: 1944: 1940: 1936: 1932: 1928: 1921: 1914: 1910: 1907: 1902: 1894: 1890: 1885: 1880: 1876: 1872: 1868: 1864: 1860: 1853: 1845: 1841: 1836: 1831: 1827: 1823: 1819: 1815: 1811: 1804: 1795: 1784: 1777: 1770: 1762: 1758: 1753: 1748: 1744: 1740: 1736: 1732: 1728: 1721: 1719: 1717: 1708: 1704: 1699: 1694: 1690: 1686: 1683:(1): 98–104. 1682: 1678: 1674: 1672: 1663: 1648: 1644: 1638: 1630: 1626: 1621: 1616: 1611: 1606: 1602: 1598: 1597:PLOS Medicine 1594: 1587: 1579: 1575: 1570: 1565: 1562:(4): 477–83. 1561: 1557: 1553: 1546: 1538: 1534: 1530: 1526: 1522: 1518: 1514: 1510: 1503: 1488: 1484: 1480: 1476: 1473:(9379): 227. 1472: 1468: 1467: 1459: 1452: 1444: 1438: 1434: 1427: 1425: 1416: 1412: 1407: 1402: 1398: 1394: 1390: 1386: 1379: 1371: 1367: 1363: 1359: 1355: 1351: 1347: 1343: 1342:Ophthalmology 1339: 1332: 1317:. August 2021 1316: 1312: 1306: 1291: 1287: 1281: 1273: 1267: 1263: 1256: 1254: 1252: 1250: 1248: 1246: 1244: 1242: 1233: 1229: 1224: 1219: 1215: 1211: 1207: 1203: 1202: 1197: 1190: 1175: 1171: 1167: 1161: 1159: 1150: 1146: 1142: 1138: 1134: 1130: 1123: 1121: 1112: 1108: 1103: 1098: 1094: 1090: 1086: 1082: 1078: 1071: 1069: 1067: 1058: 1054: 1050: 1046: 1042: 1038: 1037:Public Health 1031: 1029: 1027: 1018: 1014: 1009: 1004: 1000: 996: 992: 988: 984: 980: 976: 969: 967: 965: 963: 961: 959: 942: 938: 934: 928: 926: 924: 922: 920: 918: 916: 914: 912: 910: 908: 906: 904: 902: 900: 898: 896: 894: 892: 890: 888: 886: 877: 871: 863: 859: 857:9780199997909 853: 849: 848: 840: 836: 828: 819: 817: 815: 808: 803: 798: 794: 784: 781: 777: 774: 768: 766: 762: 758: 754: 750: 746: 741: 737: 735: 731: 727: 723: 719: 713: 705: 701: 692: 690: 669: 500–600 663: 400–500 657: 300–400 651: 200–300 645: 100–200 640: 601: no data 596: 595: 590: 586: 577: 575: 570: 568: 564: 560: 550: 547: 538: 535: 532: 529: 528: 527: 519: 510: 508: 504: 500: 486: 477: 473: 471: 461: 459: 455: 451: 441: 439: 435: 432: 429: 426: 423: 410: 407: 404: 401: 400: 396: 393: 390: 387: 386: 382: 379: 376: 373: 372: 369: 356: 352: 350: 346: 342: 338: 337: 326: 324: 323:corneal ulcer 316: 313: 310: 307: 303: 300: 297: 294: 292: 288: 287: 286: 283: 281: 277: 274:(named after 273: 269: 263: 261: 257: 253: 247: 245: 241: 233: 230:Ellis Island 228: 219: 217: 213: 207: 205: 201: 196: 191: 187: 185: 181: 177: 173: 169: 165: 164: 159: 150: 146: 143: 139: 136: 134: 130: 126: 122: 118: 114: 110: 108: 104: 100: 99: 95: 91: 87: 85: 81: 78: 75: 73: 69: 65: 61: 56: 52: 47: 43: 39: 34: 28: 24: 19: 5312:Eye diseases 5259:Transmission 5219: 5212: 5029:epidemiology 4858: 4674: / 4670: / 4649:Monochromacy 4581: / 4477:Heterophoria 4465: / 4164: / 4160: / 4064:hypertensive 4037: / 3858:Ciliary body 3773:Keratoglobus 3681:Episcleritis 3559:Enophthalmos 3554:Exophthalmos 3499:Trichomegaly 3494:Distichiasis 3396:Inflammation 3303: 3294: 3287: 3275: 3255: 3248: 3241: 3234: 3227: 3220:Bacteroidota 3203: 3186: 3177: 3165: 3155: 3121: 3111: 3081: 3075: 3069: 3057: 3039:Lyme disease 3031: 3025: 3015: 3003: 2991: 2968: 2958: 2873:Malnutrition 2856: 2784:Tuberculosis 2708: 2697: 2686: 2662: 2651: 2636: 2621: 2584: 2570: 2547:. Retrieved 2542: 2539:"tra·cho·ma" 2533: 2521:. Retrieved 2517: 2508: 2476:(12): e903. 2473: 2469: 2459: 2422: 2418: 2408: 2395: 2376: 2349: 2345: 2335: 2323:. Retrieved 2321:(2): 426–430 2318: 2312: 2302: 2280:(5): 500–9. 2277: 2273: 2267: 2248: 2221: 2217: 2192:. Retrieved 2186: 2155:. Retrieved 2151:the original 2141: 2129:. Retrieved 2125:the original 2115: 2103:. Retrieved 2074:. Retrieved 2070:the original 2022: 2018: 2008: 1996:. Retrieved 1992:the original 1987: 1934: 1930: 1920: 1901: 1866: 1862: 1852: 1817: 1813: 1803: 1794: 1769: 1734: 1730: 1680: 1676: 1670: 1662: 1650:. Retrieved 1646: 1637: 1600: 1596: 1586: 1559: 1555: 1545: 1512: 1508: 1502: 1490:. Retrieved 1470: 1464: 1451: 1432: 1391:(1): 37–53. 1388: 1384: 1378: 1345: 1341: 1331: 1319:. Retrieved 1314: 1305: 1293:. Retrieved 1289: 1280: 1261: 1205: 1199: 1189: 1177:. Retrieved 1169: 1132: 1128: 1084: 1080: 1043:(3): 233–6. 1040: 1036: 982: 978: 945:. Retrieved 936: 846: 839: 825: 811: 790: 782: 778: 769: 745:Ellis Island 742: 738: 714: 711: 702: 698: 685: 637: 80–100 580:Epidemiology 571: 556: 546:face-washing 542: 525: 516: 503:tetracycline 499:Azithromycin 497: 483: 474: 469: 467: 447: 436: 433: 430: 427: 424: 421: 367: 353: 334: 332: 320: 304:Swelling of 284: 272:Arlt's lines 264: 248: 237: 208: 204:tetracycline 202:and topical 200:azithromycin 192: 188: 161: 157: 156: 142:tetracycline 138:Azithromycin 107:Risk factors 96: 27: 18: 5281:Vaccination 5201:Pulse Polio 5129:Eradication 4799:Cycloplegia 4742:Photophobia 4737:Hemeralopia 4694:Hemianopsia 4672:Vision loss 4583:Aniseikonia 4574:Astigmatism 4494:Cyclotropia 4472:Hypertropia 4284:Papilledema 4256:Optic nerve 4089:Sickle cell 4069:Purtscher's 4054:Retinopathy 3922:Choroiditis 3763:Keratoconus 3584:Conjunctiva 3461:Xanthelasma 3413:Blepharitis 3172:Psittacosis 3147:Chlamydiota 2688:MedlinePlus 2523:21 December 2352:: 395–403. 2194:3 September 1647:www.who.int 1492:30 December 1406:11336/26316 1170:www.who.int 757:sulfonamide 730:Middle East 695:Elimination 631: 60–80 625: 40–60 619: 20–40 613: 10–20 494:Antibiotics 480:Antibiotics 306:lymph nodes 270:are called 195:antibiotics 41:Other names 5301:Categories 5264:horizontal 5090:Rinderpest 5083:Successful 5002:(regional) 4926:Successful 4848:Infections 4769:Anisocoria 4732:Asthenopia 4725:subjective 4709:homonymous 4704:bitemporal 4656:Nyctalopia 4644:Dichromacy 4588:Presbyopia 4549:Refraction 4370:Strabismus 4260:Optic disc 3619:Pinguecula 3484:Trichiasis 3113:Leptospira 2710:Patient UK 2664:DiseasesDB 2549:19 January 2157:8 November 1998:1 November 1931:The Lancet 1652:11 October 1466:The Lancet 1458:"Trachoma" 1295:26 October 1179:13 January 1166:"Trachoma" 831:References 689:trichiasis 675: ≥600 563:ulceration 489:Management 444:Prevention 341:secretions 299:Trichiasis 168:roughening 151:80 million 133:Medication 116:Prevention 5307:Blindness 4820:Nystagmus 4794:Mydriasis 4668:Blindness 4614:Amblyopia 4602:Blindness 4562:Hyperopia 4487:Exophoria 4482:Esophoria 4467:Exotropia 4463:Esotropia 4001:Retinitis 3699:Keratitis 3676:Scleritis 3609:Pterygium 3489:Madarosis 3436:Ectropion 3431:Entropion 3408:Chalazion 3194:Chlamydia 3157:Chlamydia 2960:Treponema 2794:Pneumonia 2699:eMedicine 2500:253002428 1967:208793607 1951:0140-6736 1537:208790087 1362:0161-6420 999:1469-493X 870:cite book 822:Economics 818:"rough". 793:Neo-Latin 787:Etymology 607: ≤10 553:Prognosis 359:Diagnosis 349:entropion 291:discharge 180:blindness 148:Frequency 124:Treatment 72:Specialty 64:eyelashes 5286:Zoonosis 5269:vertical 5254:Pandemic 5169:Regional 5131:programs 5104:Underway 5051:Syphilis 5041:Trachoma 5009:Hookworm 5000:Underway 4949:(global) 4947:Underway 4933:Smallpox 4859:Trachoma 4624:Diplopia 4319:Ischemic 4244:Pathways 4158:Glaucoma 4059:diabetic 3961:Cataract 3899:Synechia 3751:Meesmann 3719:Exposure 3704:herpetic 3602:allergic 3592:Chemosis 3526:Epiphora 3204:Trachoma 3017:Borrelia 2976:Syphilis 2857:Trachoma 2715:Trachoma 2572:trachoma 2492:36265506 2451:Archived 2447:46535213 2439:11700815 2384:Archived 2368:16693194 2325:4 August 2294:12431697 2256:Archived 2131:5 August 2076:11 April 2049:15550216 1959:25043452 1909:Archived 1893:16170117 1844:26568232 1783:Archived 1761:22336798 1707:20409284 1629:24586120 1529:18539226 1487:12885486 1415:23870458 1370:24424250 1321:21 April 1232:15489358 1149:15525727 1111:25697765 1057:22325616 1017:31554017 947:14 March 941:Archived 862:Archived 807:trākhōma 804:τράχωμα 797:trāchōma 254:and the 244:pink eye 158:Trachoma 84:Symptoms 36:Trachoma 5061:Leprosy 5036:Rubella 5024:vaccine 5019:Measles 4976:Malaria 4699:binasal 4686:Anopsia 4629:Scotoma 4423:palsies 4186:Red eye 4171:Floater 3978:Aphakia 3909:Choroid 3879:Hyphema 3869:Uveitis 3476:Eyelash 2922:due to 2822:Cholera 2789:Measles 2779:Malaria 2704:oph/118 2658:D014141 2359:1315791 2240:6991041 2231:1805119 2105:13 June 2040:3328994 1884:1772881 1835:4661324 1752:4422499 1698:2867063 1620:3934994 1578:3500800 1569:2491032 1102:4441394 1008:6760986 814:trākhus 800:, from 708:History 513:Surgery 345:fomites 170:of the 5192:India 5138:Global 5056:Rabies 4789:Miosis 4567:Myopia 4346:Kjer's 4094:photic 3993:Retina 3746:Fuchs' 3714:fungal 3691:Cornea 3668:Sclera 3451:Ptosis 3388:Eyelid 3376:Adnexa 2804:Plague 2693:001486 2498:  2490:  2445:  2437:  2366:  2356:  2292:  2238:  2228:  2047:  2037:  1965:  1957:  1949:  1927:West S 1891:  1881:  1842:  1832:  1759:  1749:  1705:  1695:  1627:  1617:  1576:  1566:  1535:  1527:  1509:Lancet 1485:  1439:  1413:  1368:  1360:  1268:  1230:  1223:523557 1220:  1147:  1109:  1099:  1055:  1015:  1005:  997:  854:  732:, and 728:, the 726:Africa 677: 673:  667:  661:  655:  649:  643:  635:  629:  623:  617:  611:  605:  599:  567:cornea 507:Pfizer 280:pannus 256:sclera 252:cornea 176:cornea 93:Causes 4966:Polio 4813:Other 4761:Pupil 4151:Other 3795:sicca 3647:Globe 3546:Orbit 2998:Pinta 2980:bejel 2669:29100 2496:S2CID 2443:S2CID 1963:S2CID 1786:(PDF) 1779:(PDF) 1533:S2CID 1461:(PDF) 802:Greek 329:Cause 4986:Yaws 3953:Lens 3853:Iris 3403:Stye 2985:Yaws 2926:non- 2774:AIDS 2653:MeSH 2642:9-CM 2551:2014 2525:2017 2488:PMID 2435:PMID 2364:PMID 2327:2009 2319:XLIV 2290:PMID 2236:PMID 2196:2018 2159:2014 2133:2015 2107:2018 2078:2013 2045:PMID 2000:2018 1955:PMID 1947:ISSN 1889:PMID 1840:PMID 1757:PMID 1703:PMID 1654:2023 1625:PMID 1574:PMID 1525:PMID 1494:2022 1483:PMID 1437:ISBN 1411:PMID 1366:PMID 1358:ISSN 1323:2023 1297:2022 1266:ISBN 1228:PMID 1181:2023 1145:PMID 1107:PMID 1085:2015 1053:PMID 1013:PMID 995:ISSN 949:2014 876:link 852:ISBN 771:the 734:Asia 289:Eye 212:US$ 62:and 2932:BV4 2647:076 2638:ICD 2632:A71 2623:ICD 2478:doi 2427:doi 2423:175 2354:PMC 2282:doi 2226:PMC 2035:PMC 2027:doi 1939:doi 1935:384 1879:PMC 1871:doi 1830:PMC 1822:doi 1747:PMC 1739:doi 1693:PMC 1685:doi 1615:PMC 1605:doi 1564:PMC 1517:doi 1513:371 1475:doi 1471:362 1401:hdl 1393:doi 1389:100 1350:doi 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Index

Trachoma (disambiguation)

in-turned eyelid
eyelashes
Specialty
Infectious disease
Symptoms
Chlamydia trachomatis
Risk factors
Medication
Azithromycin
tetracycline
Chlamydia trachomatis
roughening
inner surface of the eyelids
cornea
blindness
eyelids turn inward
antibiotics
azithromycin
tetracycline
US$
neglected tropical diseases

Public Health Service
conjunctivitis
pink eye
cornea
sclera
pus

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