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Hamartoma

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85: 291: 415: 39: 406:. The symptoms typically begin in early infancy and are progressive, often into general cognitive and/or functional disability. Moreover, resection is usually difficult, as the growths are generally adjacent to, or even intertwined with, the optic nerve. Symptoms tend to be resistant to medical control; however, surgical techniques are improving and can result in immense improvement of prognosis. 232:
Hamartomas are caused by abnormal formation in normal tissue and can occur spontaneously or as a result of an underlying disorder. Hamartomas are most likely the result of developmental error and can manifest itself in multiple locations. The development of hamartomas has also been linked
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Hamartomas, while generally benign, can cause problems due to their location. For example, when located on the skin, especially on the face or neck, they can be very disfiguring. Cases have been reported of hamartomas the size of a small orange. They may obstruct practically any organ in the body,
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within the kidneys, lungs or pancreas are interpreted by some experts as hamartomas while others consider them true neoplasms. Moreover, even though hamartomas show a benign histology, there is a risk of some rare but life-threatening complications such as those found in
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Parenchymal hamartoma of the lung. The surrounding lung falls away from the well-circumscribed mass, a typical feature of these lesions. The hamartoma shows a variegated yellow and white appearance, which corresponds respectively to fat and
166:(undetected until they are found incidentally on an imaging study obtained for another reason). Additionally, the definition of hamartoma versus benign neoplasm is often unclear, since both lesions can be clonal. Lesions such as 1079:
GrigoraƟ, Adriana; Amălinei, Cornelia; Lovin, Ciprian Sebastian; GrigoraƟ, Constantin Cristian; Pricope, Diana Lavinia; Costin, Constantin Aleodor; Chiseliƣă, Irina Rodica; CriƟan-Dabija, Radu Adrian (February 18, 2023).
1336:"Cardiovascular Manifestations of Tuberous Sclerosis Complex and Summary of the Revised Diagnostic Criteria and Surveillance and Management Recommendations From the International Tuberous Sclerosis Consensus Group" 1783: 1768: 1753: 422:
Renal hamartomas are benign tumors that most likely developed from birth defects in the organ. They are frequently abundant in blood vessels and contain varying amounts of fat and smooth muscle components.
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and increases the risk of developing cancer in many different tissues, but particularly in the endometrium, thyroid, and breast. It is inherited autosomally dominantly, with a germ-line mutation of the
50:. The hamartoma is the dark circular object on the left that dominates the image. This is a cross-section; the growth is about 9 cm in diameter, while the entire spleen is about 11 cm in diameter. 928:
De Cicco C, Bellomi M, Bartolomei M, Carbone G, Pelosi G, Veronesi G, et al. (December 2008). "Imaging of lung hamartomas by multidetector computed tomography and positron emission tomography".
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is sometimes considered synonymous with neoplasm. Hamartomas are by definition benign, slow-growing or self-limiting, though the underlying condition may still predispose the individual towards
513:. They can be removed surgically if necessary, and are not likely to recur. Prognosis will depend upon the location and size of the lesion, as well as the overall health of the patient. 131:
of local tissue but is usually due to an overgrowth of multiple aberrant cells, with a basis in a systemic genetic condition, rather than a growth descended from a single mutated cell (
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is an uncommon hereditary disorder marked by numerous hamartomas in a range of tissues from all three layers of the embryo. This is a syndrome that predisposes people to
442:, a pancreatic rest may appear to be a submucosal mass or gastric neoplasm. Most are asymptomatic, but they can cause dyspepsia or upper gastrointestinal bleeding. 303:
and about 75% of all benign lung tumors, are hamartomas. Ten percent of hamartomas are endobronchial lesions, with the majority occurring in the peripheral lung
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Shah, A.; Gordon, A.R.; Ginsberg, G.G.; Furth, E.E.; Levine, M.S. (2007). "Ectopic pancreatic rest in the proximal stomach mimicking gastric neoplasms".
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Palmisano, Peter J. (1967). "Renal Hamartoma (Angiomyolipoma): Its Angiographic Appearance and Response to Intra-Arterial Epinephrine".
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Smith J, Klostermann C, Harm T, Breuer R, Kovalik DA, Bornkamp J, Yaeger M (August 2017). "Abomasal hamartoma in a La Mancha wether".
2008: 2494: 965:"Case Report: Resection of Giant Endotracheal Hamartoma by Electrosurgical Snaring via Fiberoptic Bronchoscopy in a 9-Year-Old Boy" 2054: 1253:
Hansen, Torsten; Katenkamp, Detlef (August 18, 2005). "Rhabdomyoma of the head and neck: morphology and differential diagnosis".
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Sim, Jongmin; Ahn, Hye In; Han, Hulin; Jun, Young Jin; Rehman, Abdul; Jang, Se Min; Jang, Kiseok; Paik, Seung Sam (2013).
402:, and can cause visual problems, other seizures, rage disorders associated with hypothalamic diseases, and early onset of 206:. The two can be differentiated as follows: a hamartoma is an excess of normal tissue in a normal situation (e.g., a 2107: 623: 460:
immunopositivity. It is made up of an unusual combination of typical splenic components, like red and white pulp.
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on the skin), while a choristoma is an excess of tissue in an abnormal situation (e.g., pancreatic tissue in the
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Hinton, Robert B.; Prakash, Ashwin; Romp, Robb L.; Krueger, Darcy A.; Knilans, Timothy K. (December 17, 2014).
2499: 2422: 1955: 439: 265: 135:), as would typically define a benign neoplasm/tumor. Despite this, many hamartomas are found to have clonal 1762: 2013: 527: 378:
Sometimes nerves can also be affected. The most common nerve to be affected by hamartoma is reported to be
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tumor that originated from striated muscle. Usually, it affects the head and neck. It has been found that
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Lung hamartomas are more common in men than in women, and may present additional difficulties in smokers.
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Splenic hamartoma is an uncommon benign vascular proliferative tumor that is identified by the vascular
327:, depending on the size and location. Typically, lung hamartomas appear as solitary nodules on thoracic 2453: 2069: 1918: 269: 2247: 2038: 1950: 1456: 2282: 2240: 2033: 1798: 188: 84: 2375: 2339: 2277: 1730: 1082:"The clinicopathological challenges of symptomatic and incidental pulmonary hamartomas diagnosis" 522: 427: 136: 555: 2380: 2334: 2064: 1978: 395: 307:. Peripheral pulmonary hamartomas typically do not cause any symptoms. Patients may experience 203: 2432: 2413: 2059: 1911: 2385: 2230: 2220: 2100: 359: 355: 155: 2085: 1849: 1194:
Vuckovic, Dejan C; Koledin, Milos P; Vuckovic, Nada M; Koledin, Bojan M (March 25, 2020).
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Batsakis JG (1984-01-01). "Pathology consultation. Nomenclature of developmental tumors".
8: 2272: 2204: 1787: 328: 316: 1114: 1081: 2365: 1973: 1634: 1599: 1580: 1425: 1392: 1368: 1335: 1286: 1230: 1195: 1171: 1139:"Large multicystic pulmonary chondroid hamartoma in a child presenting as pneumothorax" 1138: 1056: 1023: 999: 964: 905: 870: 846: 819: 795: 768: 674: 435: 351: 257: 192: 162:. Hamartomas occur in many different parts of the body and are most often asymptomatic 1792: 1039: 2468: 2458: 2370: 2184: 2025: 1809: 1682: 1674: 1639: 1621: 1545: 1537: 1502: 1494: 1430: 1412: 1373: 1355: 1309: 1278: 1270: 1235: 1217: 1176: 1158: 1119: 1101: 1061: 1043: 1004: 986: 945: 941: 910: 892: 851: 800: 747: 697: 666: 610: 608: 587: 497:, etc. They are particularly likely to cause major health issues when located in the 93: 69: 1584: 678: 438:
pancreatic tissue found in the stomach, duodenum, or proximal jejunum. When seen on
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A hamartoma has been identified as a cause of partial outflow obstruction in the
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Farooq, A.; Walker, L.J.; Bowling, J.; Audisio, R.A. (2010). "Cowden syndrome".
1393:"Fibrolipomatous Hamartoma (FLH) of Median Nerve: A Rare Case Report and Review" 1305: 583: 2395: 2353: 1988: 1814: 1670: 1533: 1408: 1391:
Ranjan, Rajni; Kumar, Rakesh; Jeyaraman, Madhan; Kumar, Sudhir (June 1, 2020).
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Wu, Lei; Chen, Wei; Li, PengCheng; Li, Shuxian; Chen, Zhimin (April 27, 2021).
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of all or at least multiple cells. Many of these conditions are classified as
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Saadi, Muslim M.; Barakeh, Duna H.; Husain, Sufia; Hajjar, Waseem M. (2015).
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that are acquired through somatic mutations, and on this basis the term
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Journal of International Society of Preventive and Community Dentistry
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Jorquera JP, Rubio-Palau J, Cazalla AA, RodrĂ­guez-Carunchio L (2016).
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Hamartomas are usually caused by a genetic syndrome that affects the
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Lee KH, Roland PS (2013). "Heterotopias, Teratoma, and Choristoma".
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SINGH, HARIQBAL; KHANNA, SK; CHANDRAN, VIJAY; Jetley, RK (1999).
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is a mostly benign, local malformation of cells that resembles a
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Patil, Shankargouda; Rao, RoopaS; Majumdar, Barnali (2015).
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Sarkar, Sharmila; Siddiqui, Waqas J. (November 14, 2022).
224:("error"), and was introduced by D.P.G. Albrecht in 1904. 16:
Tumour-like overgrowth due to a systemic genetic condition
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Kumar V, Abbas AK, Fausto N, Aster JC (27 August 2014).
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tumor suppressor gene present in about 80% of patients.
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Goswamy M, Tabasum S, Kudva P, Gupta S (January 2012).
696:(9th ed.). Elsevier Health Sciences. p. 481. 577: 575: 573: 956: 736:
Encyclopedia of Otolaryngology, Head and Neck Surgery
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One of the most troublesome hamartomas occurs on the
1735: 769:"Choristoma: A rare congenital tumor of the tongue" 582:Ali, Syed Awab; Mulita, Francesk (March 14, 2023). 570: 410:Kidneys, stomach, spleen and other vascular organs 651:The Annals of Otology, Rhinology, and Laryngology 2486: 1610:(7). Baishideng Publishing Group Inc.: 217–219. 868: 1252: 1092:(4). Societatea Romana de Morfologie: 607–613. 331:(CT) scans, with a diameter of less than 4 cm. 1303: 2101: 1919: 1086:Romanian Journal of Morphology and Embryology 256:Disorders associated with hamartomas include 1597: 824:Journal of Indian Society of Periodontology 2108: 2094: 1926: 1912: 962: 83: 37: 1633: 1615: 1476: 1424: 1367: 1340:Journal of the American Heart Association 1229: 1211: 1170: 1113: 1055: 998: 980: 904: 886: 845: 835: 794: 784: 733: 581: 820:"Osseous choristoma of the periodontium" 648: 449:(true gastric stomach) of a dairy goat. 413: 289: 2487: 546: 2089: 1907: 1196:"Mediastinal Cartilaginous Hamartoma" 398:is symptomatic; it most often causes 2075:Encephalocraniocutaneous lipomatosis 694:Robbin's Pathologic Basis of Disease 644: 642: 640: 418:Hamartoma in breast with ultrasound 13: 1028:Medical Journal Armed Forces India 463: 14: 2511: 2009:Bannayan–Riley–Ruvalcaba syndrome 1719: 637: 280: 1933: 942:10.1016/j.athoracsur.2008.08.033 2495:Dermal and subcutaneous growths 2055:Abdallat–Davis–Farrage syndrome 1693: 1604:World Journal of Clinical Cases 1556: 1441: 921: 871:"Hamartomas of the oral cavity" 773:Annals of Maxillofacial Surgery 385: 358:. The symptoms may manifest as 1565:Veterinary Record Case Reports 1397:Indian Journal of Orthopaedics 930:The Annals of Thoracic Surgery 811: 760: 727: 710: 685: 540: 394:. Unlike most such growths, a 266:PTEN hamartoma tumour syndrome 1: 2423:Clonally transmissible cancer 1453:Barrow Neurological Institute 1040:10.1016/s0377-1237(17)30328-3 744:10.1007/978-3-642-23499-6_642 533: 440:upper gastrointestinal series 1577:10.1136/vetreccr-2017-000515 722:Dorland's Medical Dictionary 528:List of cutaneous conditions 483: 275: 202:, a closely related form of 7: 1994:Multiple hamartoma syndrome 1665:(8). Elsevier BV: 577–583. 1528:(6). Elsevier BV: 600–602. 547:Uthman E (2 January 1999). 516: 299:About 5–8% of all solitary 218:is from the Greek áŒÎŒÎ±ÏÏ„ÎŻÎ±, 10: 2516: 2454:Index of oncology articles 1671:10.1016/j.ctrv.2010.04.002 1534:10.1016/j.crad.2007.01.001 1409:10.1007/s43465-020-00149-9 1206:(3). Cureus, Inc.: e7411. 663:10.1177/000348948409300122 620:Taber's Medical Dictionary 18: 2441: 2394: 2352: 2327: 2291: 2213: 2172: 2139: 2132: 2047: 2024: 1964: 1956:Von Hippel–Lindau disease 1941: 1835: 1739: 1308:. StatPearls Publishing. 1267:10.1007/s00428-005-0038-8 1155:10.15537/smj.2015.4.10210 1034:(1). Elsevier BV: 79–80. 586:. StatPearls Publishing. 549:"Hamartoma of the spleen" 373: 227: 92: 68: 54: 46:A large hamartoma of the 45: 36: 31: 2014:Lhermitte–Duclos disease 1659:Cancer Treatment Reviews 982:10.3389/fped.2021.528966 888:10.4103/2231-0762.164789 786:10.4103/2231-0746.200342 337: 189:neurofibromatosis type I 19:Not to be confused with 2376:Prostate cancer staging 2340:Paraneoplastic syndrome 1983:Pallister–Hall syndrome 1705:Dermatology Image Atlas 1617:10.12998/wjcc.v1.i7.217 1449:"Hypothalmic Hamartoma" 1352:10.1161/jaha.114.001493 969:Frontiers in Pediatrics 881:(5). Medknow: 347–353. 837:10.4103/0972-124X.94619 523:Hamartia (medical term) 428:myoepithelial hamartoma 354:is linked to 80–90% of 346:is an uncommon, benign 285: 137:chromosomal aberrations 2414:Tumor suppressor genes 2381:Gleason grading system 2335:Precancerous condition 2070:Peutz–Jeghers syndrome 2065:Incontinentia pigmenti 1979:Hypothalamic hamartoma 975:. Frontiers Media SA. 738:. pp. 1179–1183. 616:"Hamartoma definition" 419: 396:hypothalamic hamartoma 296: 270:Peutz–Jeghers syndrome 2433:Carcinogenic bacteria 2173:Malignant progression 2060:Ataxia telangiectasia 1951:Sturge–Weber syndrome 1306:"Cardiac Rhabdomyoma" 1143:Saudi Medical Journal 1098:10.47162/rjme.63.4.02 1024:"Pulmonary Hamartoma" 417: 293: 198:It is different from 2500:Anatomical pathology 2386:Dukes classification 1701:"Dermatology Images" 360:pericardial effusion 356:cardiac rhabdomyomas 156:overgrowth syndromes 2205:Sentinel lymph node 1213:10.7759/cureus.7411 329:computed tomography 2253:Respiratory system 1974:Tuberous sclerosis 1836:External resources 1522:Clinical Radiology 626:on 7 December 2008 430:, also known as a 420: 352:tuberous sclerosis 297: 258:tuberous sclerosis 193:tuberous sclerosis 61:hăm-ăr-tƍâ€Čmă 2482: 2481: 2469:Cancer and nausea 2348: 2347: 2185:Carcinoma in situ 2083: 2082: 2026:Neurofibromatosis 1901: 1900: 753:978-3-642-23498-9 703:978-0-323-29639-7 657:(1 Pt 1): 98–99. 400:gelastic seizures 152:development cycle 121: 120: 94:Diagnostic method 26:Medical condition 2507: 2283:Endocrine system 2248:Digestive system 2137: 2136: 2110: 2103: 2096: 2087: 2086: 1999:Proteus syndrome 1928: 1921: 1914: 1905: 1904: 1737: 1736: 1731:Cleveland Clinic 1713: 1712: 1707:. Archived from 1697: 1691: 1690: 1654: 1648: 1647: 1637: 1619: 1595: 1589: 1588: 1560: 1554: 1553: 1517: 1511: 1510: 1491:10.1148/88.2.249 1474: 1468: 1467: 1465: 1464: 1455:. Archived from 1445: 1439: 1438: 1428: 1388: 1382: 1381: 1371: 1331: 1325: 1324: 1322: 1320: 1301: 1295: 1294: 1250: 1244: 1243: 1233: 1215: 1191: 1185: 1184: 1174: 1134: 1128: 1127: 1117: 1076: 1070: 1069: 1059: 1019: 1013: 1012: 1002: 984: 960: 954: 953: 936:(6): 1769–1772. 925: 919: 918: 908: 890: 866: 860: 859: 849: 839: 815: 809: 808: 798: 788: 764: 758: 757: 731: 725: 714: 708: 707: 689: 683: 682: 646: 635: 634: 632: 631: 622:. Archived from 612: 603: 602: 600: 598: 579: 568: 567: 565: 563: 554:. Archived from 544: 170:, developmental 160:cancer syndromes 88: 87: 75:Medical genetics 41: 29: 28: 2515: 2514: 2510: 2509: 2508: 2506: 2505: 2504: 2485: 2484: 2483: 2478: 2437: 2390: 2344: 2323: 2287: 2209: 2168: 2128: 2114: 2084: 2079: 2043: 2020: 2004:Cowden syndrome 1960: 1937: 1932: 1902: 1897: 1896: 1850:article/1254012 1831: 1830: 1748: 1722: 1717: 1716: 1699: 1698: 1694: 1655: 1651: 1596: 1592: 1561: 1557: 1518: 1514: 1475: 1471: 1462: 1460: 1447: 1446: 1442: 1389: 1385: 1332: 1328: 1318: 1316: 1302: 1298: 1255:Virchows Archiv 1251: 1247: 1192: 1188: 1135: 1131: 1077: 1073: 1020: 1016: 961: 957: 926: 922: 867: 863: 816: 812: 765: 761: 754: 732: 728: 715: 711: 704: 690: 686: 647: 638: 629: 627: 614: 613: 606: 596: 594: 580: 571: 561: 559: 558:on 15 June 2014 545: 541: 536: 519: 486: 469:Cowden syndrome 466: 464:Cowden syndrome 432:pancreatic rest 412: 388: 376: 364:hydrops fetalis 340: 288: 283: 278: 262:cowden syndrome 230: 82: 64: 27: 24: 17: 12: 11: 5: 2513: 2503: 2502: 2497: 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1227: 1223: 1219: 1214: 1209: 1205: 1201: 1197: 1190: 1182: 1178: 1173: 1168: 1164: 1160: 1156: 1152: 1148: 1144: 1140: 1133: 1125: 1121: 1116: 1111: 1107: 1103: 1099: 1095: 1091: 1087: 1083: 1075: 1067: 1063: 1058: 1053: 1049: 1045: 1041: 1037: 1033: 1029: 1025: 1018: 1010: 1006: 1001: 996: 992: 988: 983: 978: 974: 970: 966: 959: 951: 947: 943: 939: 935: 931: 924: 916: 912: 907: 902: 898: 894: 889: 884: 880: 876: 872: 865: 857: 853: 848: 843: 838: 833: 829: 825: 821: 814: 806: 802: 797: 792: 787: 782: 778: 774: 770: 763: 755: 749: 745: 741: 737: 730: 724: 723: 718: 713: 705: 699: 695: 688: 680: 676: 672: 668: 664: 660: 656: 652: 645: 643: 641: 625: 621: 617: 611: 609: 593: 589: 585: 578: 576: 574: 557: 553: 550: 543: 539: 529: 526: 524: 521: 520: 514: 512: 508: 504: 500: 496: 492: 481: 479: 474: 470: 461: 459: 455: 450: 448: 443: 441: 437: 433: 429: 424: 416: 407: 405: 401: 397: 393: 383: 381: 371: 369: 365: 361: 357: 353: 349: 345: 335: 332: 330: 326: 322: 319:, persistent 318: 314: 310: 306: 302: 292: 273: 271: 267: 263: 259: 254: 252: 248: 244: 240: 236: 225: 223: 222: 217: 213: 209: 205: 201: 196: 194: 190: 185: 181: 180:lymphangiomas 177: 173: 169: 165: 161: 157: 153: 148: 146: 142: 138: 134: 133:monoclonality 130: 126: 116: 112: 108: 104: 100: 97: 95: 91: 86: 80: 76: 73: 71: 67: 60: 59: 57: 55:Pronunciation 53: 49: 44: 40: 35: 30: 22: 2163: 2116:Overview of 1965: 1943:Angiomatosis 1935:Phakomatosis 1887: 1876: 1865: 1854: 1843: 1819: 1808: 1797: 1782: 1767: 1752: 1709:the original 1704: 1695: 1662: 1658: 1652: 1607: 1603: 1593: 1568: 1564: 1558: 1525: 1521: 1515: 1482: 1478: 1472: 1461:. Retrieved 1457:the original 1452: 1443: 1400: 1396: 1386: 1343: 1339: 1329: 1317:. Retrieved 1299: 1258: 1254: 1248: 1203: 1199: 1189: 1146: 1142: 1132: 1089: 1085: 1074: 1031: 1027: 1017: 972: 968: 958: 933: 929: 923: 878: 874: 864: 827: 823: 813: 776: 772: 762: 735: 729: 720: 717:"Choristoma" 712: 693: 687: 654: 650: 628:. Retrieved 624:the original 619: 595:. Retrieved 560:. Retrieved 556:the original 552: 542: 499:hypothalamus 489:such as the 487: 467: 451: 444: 431: 425: 421: 392:hypothalamus 389: 386:Hypothalamus 380:median nerve 377: 368:heart blocks 344:rhabdomyomas 341: 333: 301:lung nodules 298: 255: 231: 219: 215: 214:). The term 197: 184:rhabdomyomas 149: 145:malignancies 140: 124: 122: 115:bronchoscopy 2464:Cancer pain 2404:Cancer cell 2149:Hyperplasia 1867:Radiopaedia 1319:January 28, 597:October 10, 584:"Hamartoma" 454:endothelial 348:mesenchymal 233:to certain 204:heterotopia 176:hemangiomas 99:Chest x-ray 2489:Categories 2409:Carcinogen 2273:Urogenital 2214:Topography 2195:Metastasis 2159:Pseudocyst 2133:Conditions 1856:Patient UK 1810:DiseasesDB 1463:2013-01-09 630:2008-09-25 534:References 325:chest pain 309:hemoptysis 305:parenchyma 295:cartilage. 200:choristoma 111:ultrasound 2428:Oncovirus 2418:oncogenes 2371:Ann Arbor 2314:Papilloma 2299:Carcinoma 2292:Histology 2236:laryngeal 2180:Dysplasia 2164:Hamartoma 1966:Hamartoma 1861:Hamartoma 1845:eMedicine 1821:SNOMED CT 1679:0305-7372 1626:2307-8960 1542:0009-9260 1499:0033-8419 1479:Radiology 1417:0019-5413 1360:2047-9980 1275:0945-6317 1222:2168-8184 1163:0379-5284 1106:1220-0522 1048:0377-1237 991:2296-2360 897:2231-0762 484:Prognosis 313:pneumonia 276:Diagnosis 216:hamartoma 208:birthmark 141:hamartoma 125:hamartoma 79:pathology 70:Specialty 32:Hamartoma 2449:Research 2309:Blastoma 2126:oncology 1878:Orphanet 1826:51398009 1687:20580873 1644:24340270 1585:80240747 1550:17467399 1435:34113430 1378:25424575 1314:32809444 1283:16133368 1240:32337135 1181:25828288 1124:36808195 1115:10028331 1066:28775580 1009:33987147 950:19021972 915:26539384 856:22628977 805:28299279 679:75206651 592:32965969 517:See also 447:abomasum 342:Cardiac 237:such as 221:hamartia 212:duodenum 168:adenomas 129:neoplasm 21:hematoma 2459:History 2358:grading 2354:Staging 2319:Adenoma 2304:Sarcoma 2039:Type II 1892:Q525075 1888:Scholia 1804:D006222 1726:DermNet 1635:3856295 1507:6016922 1426:8149561 1369:4338742 1291:8031365 1231:7182163 1172:4404485 1057:5531795 1000:8111287 906:4606596 847:3357020 796:5343649 671:6703601 562:30 July 503:kidneys 436:ectopic 404:puberty 317:dyspnea 103:CT scan 2190:Cancer 2122:cancer 2118:tumors 2034:Type I 1763:LD2D.Z 1685:  1677:  1642:  1632:  1624:  1583:  1548:  1540:  1505:  1497:  1433:  1423:  1415:  1376:  1366:  1358:  1312:  1289:  1281:  1273:  1238:  1228:  1220:  1200:Cureus 1179:  1169:  1161:  1122:  1112:  1104:  1064:  1054:  1046:  1007:  997:  989:  948:  913:  903:  895:  854:  844:  803:  793:  750:  700:  677:  669:  590:  511:spleen 473:cancer 374:Nerves 323:, and 268:, and 251:BMPR1A 249:, and 228:Causes 113:, and 81:  48:spleen 2442:Misc. 2328:Other 2268:Blood 2048:Other 1883:79386 1872:74428 1815:19785 1793:759.6 1778:Q85.9 1581:S2CID 1287:S2CID 675:S2CID 509:, or 491:colon 434:, is 366:, or 338:Heart 321:cough 239:SMAD4 235:genes 172:cysts 2474:Diet 2263:Skin 2258:Bone 2226:oral 2154:Cyst 2124:and 1799:MeSH 1788:9-CM 1683:PMID 1675:ISSN 1640:PMID 1622:ISSN 1546:PMID 1538:ISSN 1503:PMID 1495:ISSN 1431:PMID 1413:ISSN 1374:PMID 1356:ISSN 1321:2024 1310:PMID 1279:PMID 1271:ISSN 1236:PMID 1218:ISSN 1177:PMID 1159:ISSN 1120:PMID 1102:ISSN 1062:PMID 1044:ISSN 1005:PMID 987:ISSN 946:PMID 911:PMID 893:ISSN 852:PMID 801:PMID 748:ISBN 698:ISBN 667:PMID 599:2023 588:PMID 564:2014 507:lips 478:PTEN 286:Lung 247:STK1 243:PTEN 191:and 182:and 2366:TNM 1784:ICD 1769:ICD 1754:ICD 1667:doi 1630:PMC 1612:doi 1573:doi 1530:doi 1487:doi 1421:PMC 1405:doi 1364:PMC 1348:doi 1263:doi 1259:447 1226:PMC 1208:doi 1167:PMC 1151:doi 1110:PMC 1094:doi 1052:PMC 1036:doi 995:PMC 977:doi 938:doi 901:PMC 883:doi 842:PMC 832:doi 791:PMC 781:doi 740:doi 719:at 659:doi 495:eye 458:CD8 158:or 107:MRI 2491:: 2120:, 1890:: 1881:: 1870:: 1859:: 1848:: 1824:: 1813:: 1802:: 1791:: 1776:: 1773:10 1761:: 1758:11 1703:. 1681:. 1673:. 1663:36 1661:. 1638:. 1628:. 1620:. 1606:. 1602:. 1579:. 1567:. 1544:. 1536:. 1526:62 1524:. 1501:. 1493:. 1483:88 1481:. 1451:. 1429:. 1419:. 1411:. 1401:55 1399:. 1395:. 1372:. 1362:. 1354:. 1342:. 1338:. 1285:. 1277:. 1269:. 1257:. 1234:. 1224:. 1216:. 1204:12 1202:. 1198:. 1175:. 1165:. 1157:. 1147:36 1145:. 1141:. 1118:. 1108:. 1100:. 1090:63 1088:. 1084:. 1060:. 1050:. 1042:. 1032:55 1030:. 1026:. 1003:. 993:. 985:. 971:. 967:. 944:. 934:86 932:. 909:. 899:. 891:. 877:. 873:. 850:. 840:. 828:16 826:. 822:. 799:. 789:. 775:. 771:. 746:. 673:. 665:. 655:93 653:. 639:^ 618:. 607:^ 572:^ 551:. 505:, 501:, 493:, 426:A 382:. 370:. 362:, 315:, 272:. 264:, 260:, 253:. 245:, 241:, 195:. 178:, 174:, 147:. 123:A 109:, 105:, 101:, 77:, 2416:/ 2356:/ 2109:e 2102:t 2095:v 1985:) 1981:( 1927:e 1920:t 1913:v 1786:- 1771:- 1756:- 1746:D 1689:. 1669:: 1646:. 1614:: 1608:1 1587:. 1575:: 1569:5 1552:. 1532:: 1509:. 1489:: 1466:. 1437:. 1407:: 1380:. 1350:: 1344:3 1323:. 1293:. 1265:: 1242:. 1210:: 1183:. 1153:: 1126:. 1096:: 1068:. 1038:: 1011:. 979:: 973:9 952:. 940:: 917:. 885:: 879:5 858:. 834:: 807:. 783:: 777:6 756:. 742:: 706:. 681:. 661:: 633:. 601:. 566:. 117:. 23:.

Index

hematoma

spleen
Specialty
Medical genetics
pathology
Edit this on Wikidata
Diagnostic method
Chest x-ray
CT scan
MRI
ultrasound
bronchoscopy
neoplasm
monoclonality
chromosomal aberrations
malignancies
development cycle
overgrowth syndromes
cancer syndromes
incidentalomas
adenomas
cysts
hemangiomas
lymphangiomas
rhabdomyomas
neurofibromatosis type I
tuberous sclerosis
choristoma
heterotopia

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