Atypical antipsychotic

3758:

antipsychotics work at the synapse by binding to the receptor. Antipsychotics are completely metabolized in the body and the metabolites are excreted in urine. These drugs have relatively long half-lives. Each drug has a different half-life, but the occupancy of the D2 receptor falls off within 24 hours with atypical antipsychotics, while lasting over 24 hours for the typical antipsychotics. This may explain why relapse into psychosis happens quicker with atypical antipsychotics than with typical antipsychotics, as the drug is excreted faster and is no longer working in the brain. Physical dependence with these drugs is very rare. However, if the drug is abruptly discontinued, psychotic symptoms, movement disorders, and sleep difficulty may be observed. It is possible that withdrawal is rarely seen because the AAP are stored in body fat tissues and slowly released.

1093:. It is not possible to truly know the risks of tardive dyskinesia when taking atypicals, because tardive dyskinesia can take many decades to develop and the atypical antipsychotics are not old enough to have been tested over a long enough period of time to determine all of the long-term risks. One hypothesis as to why atypicals have a lower risk of tardive dyskinesia is because they are much less fat-soluble than the typical antipsychotics and because they are readily released from D2 receptor and brain tissue. The typical antipsychotics remain attached to the D2 receptors and accumulate in the brain tissue which may lead to TD. 389:), although more patients discontinued perphenazine owing to extrapyramidal effects compared to the atypical agents (8% vs. 2% to 4%, P=0.002). A phase 2 part of this CATIE study roughly replicated these findings. Compliance has not been shown to be different between the two types. Overall evaluations of the CATIE and other studies have led many researchers to question the first-line prescribing of atypicals over typicals, or even to question the distinction between the two classes. 401:

antidepressant response, blockade of 65% to 80% of presynaptic transport proteins—such as the serotonin reuptake pumps when considering serotoninergic antidepressants, or the norepinephrine reuptake pumps when considering noradrenergic agents such as nortriptyline—is necessary for these medications to be effective.... Depending on the level of intrinsic activity of a partial agonist and clinical goal, the clinician may aim for a different level of receptor occupancy. For example,

5334:(NHS) of the UK. Because each medication (whether first or second generation) has its own profile of desirable and adverse effects, a neuropsychopharmacologist may recommend one of the older ("typical" or first generation) or newer ("atypical" or second generation) antipsychotics alone or in combination with other medications, based on the symptom profile, response pattern, and adverse effects history of the individual patient. 11654: 40: 1051:

elderly patients with dementia. Subsequent research reports confirmed the mortality risks associated with the use of both conventional and atypical antipsychotics to treat patients with dementia. Consequently, in 2008 the FDA issued although a black box warning for classical neuroleptics. Data on treatment efficacies are strongest for atypical antipsychotics. Adverse effects in patients with

1125:, but clinical experience with these newer agents is not as developed as that with the older agents. The mechanism of these adverse effects is not completely understood but it is believed to result from a complex interaction between a number of pharmacologic actions of these drugs. Their effects on weight are believed to mostly derive from their actions on the 410:

receptors, and displacing endogenous dopamine, allows aripiprazole to replace the background or tonic tone of dopamine, which has been measured at 19% in people with schizophrenia and 9% in controls. Clinically, this still appears as the minimal effective dose achieving maximal response without significant parkinsonism despite >90% receptor occupancy.

2439:. Increased norepinephrine can cause increased glucose(blood sugar) levels. Increased blood sugar levels by increased norepinephrine causes hunger in many humans, which is why weight gain occurs with some antipsychotics if the norepinephrine is not inhibited. Inhibition of norepinephrine stabilizes mood in humans. 5280:

drugs fail. Clozapine can cause agranulocytosis (a decreased number of white blood cells), requiring blood monitoring for the patient. Despite the effectiveness of clozapine for treatment-resistant schizophrenia, agents with a more favorable side-effect profile were sought for widespread use. During the 1990s,

5342:

Between May 2007 and April 2008, 5.5 million Americans filled at least one prescription for an atypical antipsychotic. In patients under the age of 65, 71% of patients were prescribed an atypical antipsychotic to treat Schizophrenia or Bipolar Disorder where this dropped to 38% in patients aged 65 or

5279:

and the development of an adverse event monitoring system, clozapine re-emerged as a viable antipsychotic. According to Barker (2003), the three most-accepted atypical drugs are clozapine, risperidone, and olanzapine. However, he goes on to explain that clozapine is usually the last resort when other

2248:

recommends a gradual withdrawal when discontinuing antipsychotics to avoid acute withdrawal syndrome or rapid relapse. Symptoms of withdrawal commonly include nausea, vomiting, and loss of appetite. Other symptoms may include restlessness, increased sweating, and trouble sleeping. Less commonly there

1189:

The two atypical antipsychotics with trials showing that had a low incidence of weight gain in large meta-analysis were lurasidone and aripiprazole. In a meta-analysis of 18 antipsychotics, olanzapine and clozapine exhibited the worst metabolic parameters and aripiprazole, brexpiprazole, cariprazine,

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that the medication has been associated with an increased risk of mortality in elderly patients. In 2005, the FDA issued an advisory warning of an increased risk of death when atypical antipsychotics are used in dementia. In the subsequent 5 years, the use of atypical antipsychotics to treat dementia

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outperformed perphenazine in discontinuation rate (the rate at which people stopped taking it due to its effects). The authors noted an apparent superior efficacy of olanzapine to the other drugs in terms of reduction in psychopathology and rate of hospitalizations, but olanzapine was associated with

310:

or atypical antipsychotics are better. Both have equal drop-out and symptom relapse rates when typicals are used at low to moderate dosages. There is a good response in 40–50% of patients, a partial response in 30–40%, and treatment resistance (failure of symptoms to respond satisfactorily after six

5997:

The route of administration in this category refers to the standard means of administration when the drug is being used in its capacity as an atypical antipsychotic, not for other purposes. For example, amisulpride can be administered intravenously as an antiemetic drug but this is not its standard

2533:

antagonism, which is seen in atypical antipsychotics), or the positive mood, mood stabilization, and cognitive improvement effect resulting from atypical antipsychotic serotonergic activity is greater for the overall quality of life effect of an atypical antipsychotic is a question that is variable

1055:

include an increased risk of mortality and cerebrovascular events, as well as metabolic effects, extrapyramidal symptoms, falls, cognitive worsening, cardiac arrhythmia, and pneumonia. Conventional antipsychotics may pose an even greater safety risk. No clear efficacy evidence exists to support the

1050:

In April 2005, the US Food and Drug Administration (FDA) issued an advisory and subsequent black box warning regarding the risks of atypical antipsychotic use among elderly patients with dementia. The FDA advisory was associated with decreases in the use of atypical antipsychotics, especially among

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to be effective, aripiprazole receptor binding at effective antipsychotic doses is 90% to 95%. Since aripiprazole has an intrinsic activity of approximately 30% (i.e., when it binds, it stimulates the D2 receptor to about 30% of the effect of dopamine binding to the receptor), binding to 90% of the

400:

In general, when an antagonist of a neurotransmitter receptor is used, it must occupy a minimum of 65% to 70% of the target receptor to be effective. This is clearly the case when the target is a postsynaptic receptor, such as the dopamine D2 receptor. Similarly, despite significant variability in

213:

As experience with these agents has grown, several studies have questioned the utility of broadly characterizing antipsychotic drugs as "atypical/second generation" as opposed to "first generation", noting that each agent has its own efficacy and side-effect profile. It has been argued that a more

1209:

A study by Sernyak and colleagues found that the prevalence of diabetes in atypical antipsychotic treatments was statistically significantly higher than that of conventional treatment. The authors of this study suggest that it is a causal relationship the Kabinoff et al. suggest the findings only

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Atypical antipsychotics are most commonly administered orally. Antipsychotics can also be injected, but this method is not as common. They are lipid-soluble, are readily absorbed from the digestive tract, and can easily pass the blood–brain barrier and placental barriers. Once in the brain, the

1038:

Among the other side effects that have been suggested is that atypical antipsychotics increase the risk of cardiovascular disease. Kabinoff and colleagues (2003) found that the increase in cardiovascular disease is seen regardless of the treatment received, and that it is instead caused by many

1042:

Sexual side effects have also been reported when taking atypical antipsychotics. In males antipsychotics reduce sexual interest, impair sexual performance with the main difficulties being failure to ejaculate. In females there may be abnormal menstrual cycles and infertility. In both males and

331:

The utility of broadly grouping the antipsychotics into first generation and atypical categories has been challenged. It has been argued that a more nuanced view, matching the properties of individual drugs to the needs of specific patients is preferable. While the atypical (second-generation)

5322:

The terminology can still be imprecise. The definition of "atypicality" was based upon the absence of extrapyramidal side effects, but there is now a clear understanding that atypical antipsychotics can still induce these effects (though to a lesser degree than typical antipsychotics). Recent

9942: 435:. In milder cases of mania or mixed episodes, mood stabilizer monotherapy may be attempted first. SGAs are also used to treat other aspects of the disorder (such as acute bipolar depression or as a prophylactic treatment) as adjuncts or as a monotherapy, depending on the drug. Both 1034:

than the typical antipsychotics. However, tardive dyskinesia typically develops after long-term (possibly decades) use of antipsychotics. It is not clear if atypical antipsychotics, having been in use for a relatively short time, produce a lower incidence of tardive dyskinesia.

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Stroup TS, Lieberman JA, McEvoy JP, Swartz MS, Davis SM, Rosenheck RA, et al. (April 2006). "Effectiveness of olanzapine, quetiapine, risperidone, and ziprasidone in patients with chronic schizophrenia following discontinuation of a previous atypical antipsychotic".

1121:. The general consensus is that clozapine and olanzapine are associated with the greatest effects on weight gain and decreased insulin sensitivity, followed by risperidone and quetiapine. Ziprasidone and aripiprazole are thought to have the smallest effects on weight and 5323:

literature focuses more upon specific pharmacological actions and less upon categorization of an agent as "typical" or "atypical". There is no clear dividing line between the typical and atypical antipsychotics therefore categorization based on the action is difficult.

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Wang Y, Wang D, Cheng J, Fang X, Chen Y, Yu L, Ren J, Tian Y, Zhang C (September 2021). "Efficacy and tolerability of pharmacological interventions on metabolic disturbance induced by atypical antipsychotics in adults: A systematic review and network meta-analysis".

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suggest a temporal association. Kabinoff et al. suggest that there is insufficient data from large studies to demonstrate a consistent or significant difference in the risk of insulin resistance during treatment with various atypical antipsychotics. Prescribing

214:

nuanced view in which the needs of individual patients are matched to the properties of individual drugs is more appropriate. Although atypical antipsychotics are thought to be safer than typical antipsychotics, they still have severe side effects, including

1139:

receptors, while their effects on insulin sensitivity are believed to be the result of a combination of their effects on body weight (as increased body mass is known to be a risk factor for insulin resistance) and their antagonistic effects on the

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Rothschild AJ, Williamson DJ, Tohen MF, Schatzberg A, Andersen SW, Van Campen LE, et al. (August 2004). "A double-blind, randomized study of olanzapine and olanzapine/fluoxetine combination for major depression with psychotic features".

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published the results of a major independent (not funded by the pharmaceutical companies) multi-site, double-blind study (the CATIE project). This study compared several atypical antipsychotics to an older, mid-potency typical antipsychotic,

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antagonism does not appear to be as robust as in the other pathways of the dopamine system, thereby accounting for why atypical antipsychotics still retain part of their efficacy against the positive symptoms of schizophrenia through their

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antagonistic effects in several pathways of the dopamine system. In the nigrostratial pathway, it reduces EPS. In the tuberoinfundibular pathway, it reduces or eliminates prolactin elevation. Dopamine release in the mesolimbic pathway from

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Janssen PA, Niemegeers CJ, Schellekens KH, Lenaerts FM, Verbruggen FJ, van Nueten JM, Marsboom RH, Hérin VV, Schaper WK (November 1970). "The pharmacology of fluspirilene (R 6218), a potent, long-acting and injectable neuroleptic drug".

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It has been suggested that there is no validity to the term "second-generation antipsychotic drugs" and that the drugs that currently occupy this category are not identical to each other in mechanism, efficacy, and side-effect profiles.

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Ishibashi T, Horisawa T, Tokuda K, Ishiyama T, Ogasa M, Tagashira R, et al. (July 2010). "Pharmacological profile of lurasidone, a novel antipsychotic agent with potent 5-hydroxytryptamine 7 (5-HT7) and 5-HT1A receptor activity".

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There is tentative evidence that discontinuation of antipsychotics can result in psychosis. It may also result in reoccurrence of the condition that is being treated. Rarely tardive dyskinesia can occur when the medication is stopped.

1029:

The side effects reportedly associated with the various atypical antipsychotics vary and are medication-specific. Generally speaking, atypical antipsychotics are widely believed to have a lower likelihood for the development of

336:

in particular) than typical medications, the results showing these effects often lacked robustness, and the assumption was increasingly challenged even as atypical prescriptions were soaring. In 2005 the US government body

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of schizophrenia in the short term and may worsen negative symptoms overall. Overall there is no good evidence that atypical antipsychotics have any therapeutic benefit for treating the negative symptoms of schizophrenia.

5271:(Thorazine), a typical antipsychotic, was discovered in 1951 and introduced into clinical practice shortly thereafter. Clozapine (Clozaril), an atypical antipsychotic, fell out of favor due to concerns over drug-induced 8989:"Comparative effects of 18 antipsychotics on metabolic function in patients with schizophrenia, predictors of metabolic dysregulation, and association with psychopathology: a systematic review and network meta-analysis" 6634: 4461: 6216:

Leucht S, Cipriani A, Spineli L, Mavridis D, Orey D, Richter F, et al. (September 2013). "Comparative efficacy and tolerability of 15 antipsychotic drugs in schizophrenia: a multiple-treatments meta-analysis".

11281:"Randomized controlled trial of the effect on Quality of Life of second- vs first-generation antipsychotic drugs in schizophrenia: Cost Utility of the Latest Antipsychotic Drugs in Schizophrenia Study (CUtLASS 1)" 8886:

Guenette MD, Giacca A, Hahn M, Teo C, Lam L, Chintoh A, et al. (May 2013). "Atypical antipsychotics and effects of adrenergic and serotonergic receptor binding on insulin secretion in-vivo: an animal model".

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Fischer-Barnicol D, Lanquillon S, Haen E, Zofel P, Koch HJ, Dose M, Klein HE (2008). "Typical and atypical antipsychotics--the misleading dichotomy. Results from the Working Group 'Drugs in Psychiatry' (AGATE)".

6924:"Antipsychotic Treatment Effectiveness in First Episode of Psychosis: PAFIP 3-Year Follow-Up Randomized Clinical Trials Comparing Haloperidol, Olanzapine, Risperidone, Aripiprazole, Quetiapine, and Ziprasidone" 1116:

with atypical antipsychotics. It must also be pointed out that although all atypicals must carry the warning on their labeling, some evidence shows that atypicals are not equal in their effects on weight and

294:

The first-line psychiatric treatment for schizophrenia is antipsychotic medication, which can reduce the positive symptoms of schizophrenia in about 8–15 days. Antipsychotics only appear to improve secondary

2396:

receptors in the mesocortical pathway and in the prefrontal cortex, the negative symptoms of schizophrenia, affective symptoms, and cognitive deficits and abnormalities are treated and reduced. Furthermore,

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Cipriani A, Barbui C, Salanti G, Rendell J, Brown R, Stockton S, et al. (October 2011). "Comparative efficacy and acceptability of antimanic drugs in acute mania: a multiple-treatments meta-analysis".

2411:, approved by the US FDA in 2015, has a similar binding profile to aripiprazole as a partial D2 agonist with moderate histamine binding, but with brexipiprazole has a higher affinity for serotonin receptor 1148:. Some of the newer agents, however, such as risperidone and its metabolite paliperidone, ziprasidone, lurasidone, aripiprazole, asenapine and iloperidone, have clinically insignificant effects on the 379:) did better than the typical perphenazine on the measures used, nor did they produce fewer adverse effects than the typical antipsychotic perphenazine (a result supported by a meta-analysis by Leucht 7797:"U.S. FDA Approves Otsuka and Lundbeck's REXULTI (Brexpiprazole) as Adjunctive Treatment for Adults with Major Depressive Disorder and as a Treatment for Adults with Schizophrenia | Discover Otsuka" 5326:

More recent research is questioning the notion that second-generation antipsychotics are superior to first generation typical antipsychotics. Using a number of parameters to assess quality of life,

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Both typical and atypical antipsychotics can cause tardive dyskinesia. According to one study, rates are lower with the atypicals at 3.9% per year as opposed to the typicals at 5.5% per year.

7197:

Paczynski RP, Alexander GC, Chinchilli VM, Kruszewski SP (January 2012). "Quality of evidence in drug compendia supporting off-label use of typical and atypical antipsychotic medications".

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receptor can yield absence of weight gain in an antipsychotic. This is very relevant for ziprasidone, but it creates a risk for a prolonged QTc interval. On the other hand, blockade of the

9635:

Moncrieff J (July 2006). "Does antipsychotic withdrawal provoke psychosis? Review of the literature on rapid onset psychosis (supersensitivity psychosis) and withdrawal-related relapse".

9190:

Goldstein BI, Baune BT, Bond DJ, Chen PH, Eyler L, Fagiolini A, Gomes F, Hajek T, Hatch J, McElroy SL, McIntyre RS, Prieto M, Sylvia LG, Tsai SY, Kcomt A, Fiedorowicz JG (August 2020).

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receptor and appear to carry a lower risk of insulin resistance. Whereas clozapine, olanzapine and quetiapine (indirectly via its active metabolite, norquetiapine) all antagonise the M

4447: 8044:

Taylor DM, Cornelius V, Smith L, Young AH (December 2014). "Comparative efficacy and acceptability of drug treatments for bipolar depression: a multiple-treatments meta-analysis".

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receptors in the mesolimbic pathway is responsible for the positive symptoms of schizophrenia (hallucinations, delusions, paranoia). After taking an antipsychotic, antagonism of D

11321: 9804:

Egerton A, Ahmad R, Hirani E, Grasby PM (November 2008). "Modulation of striatal dopamine release by 5-HT2A and 5-HT2C receptor antagonists: raclopride PET studies in the rat".

10866:

Tanaka O, Kondo T, Otani K, Yasui N, Tokinaga N, Kaneko S (February 1998). "Single oral dose kinetics of zotepine and its relationship to prolactin response and side effects".

10477:

Horiuchi J, McDowall LM, Dampney RA (November 2008). "Role of 5-HT(1A) receptors in the lower brainstem on the cardiovascular response to dorsomedial hypothalamus activation".

8089:"Effects of asenapine on depressive symptoms in patients with bipolar I disorder experiencing acute manic or mixed episodes: a post hoc analysis of two 3-week clinical trials" 1043:

females the breasts may become enlarged and a fluid will sometimes ooze from the nipples. Sexual adverse effects caused by some antipsychotics are a result of an increase of

405:

will act as a dopamine agonist at lower concentrations, but blocks the receptor at higher concentrations. Unlike antagonist antipsychotics, which require only 65% to 70% D2

6168:

Leucht S, Corves C, Arbter D, Engel RR, Li C, Davis JM (January 2009). "Second-generation versus first-generation antipsychotic drugs for schizophrenia: a meta-analysis".

242:

may occur. Critics have argued that "the time has come to abandon the terms first-generation and second-generation antipsychotics, as they do not merit this distinction."

11098:

Beresford R, Ward A (January 1987). "Haloperidol decanoate. A preliminary review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in psychosis".

9587:

Withdrawal of antipsychotic drugs after long-term therapy should always be gradual and closely monitored to avoid the risk of acute withdrawal syndromes or rapid relapse.

7796: 8138:

Kishi T, Iwata N (September 2013). "Efficacy and tolerability of perospirone in schizophrenia: a systematic review and meta-analysis of randomized controlled trials".

13155: 11514: 10976:

Ereshefsky L, Saklad SR, Jann MW, Davis CM, Richards A, Seidel DR (May 1984). "Future of depot neuroleptic therapy: pharmacokinetic and pharmacodynamic approaches".

11395: 18104: 9847:

de Boer SF, Koolhaas JM (December 2005). "5-HT1A and 5-HT1B receptor agonists and aggression: a pharmacological challenge of the serotonin deficiency hypothesis".

2484:

antagonism blocks serotonin and norepinephrine reuptake. Patients with increased histamine levels have been observed to have lower serotonin levels. However, the H

14482: 1186:, however, is also believed to play a crucial role in the therapeutic advantages of atypical antipsychotics over their predecessors, the typical antipsychotics. 1016:+++ Very efficacious agent. The efficacy of this treatment in the indication in question has been proven to be significantly greater than many other treatments. 17371: 12427: 2401:

receptor antagonism blocks the serotonergic excitation of cortical pyramidal cells, reducing glutamate release, which in turn lowers hyperactive dopaminergic D

2328:. If this antagonism occurs long enough, symptoms of EPS may become permanent, even if antipsychotic use is discontinued. In the tuberoinfundibular pathway, D 2506:

receptor increases caloric uptake and glucose, which is seen in clozapine and olanzapine. Other ways for dopamine to resolve is to have agonism at both the D

9744: 7234:"How CATIE brought us back to Kansas: A critical re-evaluation of the concept of atypical antipsychotics and their place in the treatment of schizophrenia" 125:) largely introduced after the 1970s and used to treat psychiatric conditions. Some atypical antipsychotics have received regulatory approval (e.g. by the 2304:

dopaminergic activity in the mesolimbic pathway also results in an anhedonic effect, reducing pleasure and motivation. In the mesocortical pathway to the

575:

Between May 2007 and April 2008, Dementia and Alzheimer's together accounted for 28% of atypical antipsychotic use in patients aged 65 or older. The U.S.

10901:

Parent M, Toussaint C, Gilson H (1983). "Long-term treatment of chronic psychotics with bromperidol decanoate: clinical and pharmacokinetic evaluation".

10564:, Janiri L (December 1999). "Clozapine blocks dopamine, 5-HT2 and 5-HT3 responses in the medial prefrontal cortex: an in vivo microiontophoretic study". 7442:

Komossa K, Depping AM, Gaudchau A, Kissling W, Leucht S (December 2010). "Second-generation antipsychotics for major depressive disorder and dysthymia".

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receptors in the mesolimbic pathway, which is mediated in some part by antipsychotics (and despite dopamine release in the mesocortical pathway from 5-HT

142: 6863:"A Randomized Comparison of Aripiprazole and Risperidone for the Acute Treatment of First-Episode Schizophrenia and Related Disorders: 3-Month Outcomes" 6093:

Miyake N, Miyamoto S, Jarskog LF (October 2012). "New serotonin/dopamine antagonists for the treatment of schizophrenia: are we making real progress?".

2316:

receptor dopamine activity is sometimes low in schizophrenia, resulting in cognitive, affective, and, broadly, the negative symptoms of schizophrenia. D

7340: 396:

Each drug has its own mechanism, as Dr. Rif S. El-Mallakh, explained regarding the binding site and occupancy with a focus on the dopamine D2 receptor:

2427:

receptor activation include decreased aggressive behavior/ideation, increased sociability, and decreased anxiety and depression. Blockade of the 5-HT

7596:"Ziprasidone Augmentation of Escitalopram for Major Depressive Disorder: Efficacy Results From a Randomized, Double-Blind, Placebo-Controlled Study" 5350:. Some healthcare professionals reported avoiding the name "atypical antipsychotic" when prescribing the drug to patients who had bipolar disorder. 14251: 12678: 6378:"Efficacy and comparative effectiveness of atypical antipsychotic medications for off-label uses in adults: a systematic review and meta-analysis" 2435:, releasing norepinephrine and dopamine within the brain. But neuronal reuptake of norepinephrine is limited sharply by some antipsychotics, e.g. 2366:

antagonist, which disinhibits the dopamine neuron, stimulating dopamine release. The result of this is that dopamine competes with antipsychotic D

19250: 13632: 12899: 6491: 7478:"Adjunctive atypical antipsychotic treatment for major depressive disorder: a meta-analysis of depression, quality of life, and safety outcomes" 2549:: Causes the appropriate neurotransmitters to be discharged in vesicles into the synapse where they attempt to bind to and activate a receptor. 19388: 16792: 14326: 14221: 13582: 12965: 11168:

Larsson M, Axelsson R, Forsman A (1984). "On the pharmacokinetics of perphenazine: a clinical study of perphenazine enanthate and decanoate".

9192:"Call to action regarding the vascular-bipolar link: A report from the Vascular Task Force of the International Society for Bipolar Disorders" 319:, especially in the short term; in the longer-terms the risks of adverse effects complicate the choice. In turn, risperidone, olanzapine, and 18935: 18890: 18598: 15138: 14191: 14018: 12929: 12823: 11545: 10290:

National Institute of Mental Health. PDSD Ki Database (Internet) . ChapelHill (NC): University of North Carolina. 1998-2013. Available from:

10173:

Shahid M, Walker GB, Zorn SH, Wong EH (January 2009). "Asenapine: a novel psychopharmacologic agent with a unique human receptor signature".

9502:

Holm AC, Edsman I, Lundberg T, Odlind B (June 1993). "Tolerability of remoxipride in the long term treatment of schizophrenia. An overview".

8987:

Pillinger T, McCutcheon RA, Vano L, Mizuno Y, Arumuham A, Hindley G, Beck K, Natesan S, Efthimiou O, Cipriani A, Howes OD (January 1, 2020).

306:

The choice of which antipsychotic to use for a specific patient is based on benefits, risks, and costs. It is debatable whether, as a class,

11133:

Reyntigens AJ, Heykants JJ, Woestenborghs RJ, Gelders YG, Aerts TJ (1982). "Pharmacokinetics of haloperidol decanoate. A 2-year follow-up".

286:). In dementia, they should only be considered after other treatments have failed and if the patient is a risk to themselves and/or others. 19878: 19853: 19428: 18192: 16946: 16777: 15600: 14882: 13868: 13827: 13777: 13722: 12713: 12693: 12510: 8182: 6918:

Gómez-Revuelta M, Pelayo-Terán JM, Juncal-Ruiz M, Vázquez-Bourgon J, Suárez-Pinilla P, Romero-Jiménez R, Setién Suero E, Ayesa-Arriola R,

19858: 19848: 19838: 19373: 19358: 19348: 19246: 18991: 18966: 18920: 18527: 18267: 18187: 17526: 16931: 16897: 15545: 15464: 15073: 14792: 14475: 12955: 2362:

receptors, the dopamine neuron is inhibited, thus acting as a brake on dopamine release. This brake is disrupted through action of a 5-HT

10607:

Navari RM (January 2014). "Olanzapine for the prevention and treatment of chronic nausea and chemotherapy-induced nausea and vomiting".

9998: 5315:. In the past, most researchers have agreed that the defining characteristics of atypical antipsychotics are the decreased incidence of 19782: 19353: 18986: 18981: 18808: 18151: 17427: 16736: 15590: 15580: 15083: 14271: 12975: 12536: 12420: 10741: 5415: 1206:

have low propensity to cause weight gain. Lumateperone was found to cause minimal weight gain in a long-term 12 month follow-up study.

1065: 19868: 19863: 19285: 14747: 14742: 14737: 13215: 12657: 12603: 6822:"Clozapine v. first- and second-generation antipsychotics in treatment-refractory schizophrenia: systematic review and meta-analysis" 20063: 17842: 17226: 16383: 14438: 14346: 11686: 11658: 10923:

Jørgensen A, Overø KF (1980). "Clopenthixol and flupenthixol depot preparations in outpatient schizophrenics. III. Serum levels".

8618:

Lykouras L, Zervas IM, Gournellis R, Malliori M, Rabavilas A (September 1, 2000). "Olanzapine and obsessive-compulsive symptoms".

20023: 17854: 17238: 16395: 14993: 14402: 7821: 20050: 20041: 14468: 14420: 14411: 12753: 12748: 7645:"Quetiapine monotherapy in acute phase for major depressive disorder: a meta-analysis of randomized, placebo-controlled trials" 1047:. Sulpiride and Amisulpiride, as well as Risperdone and paliperidone (to a lesser extent), cause a high increase of prolactin. 6861:

Robinson DG, Gallego JA, John M, Petrides G, Hassoun Y, Zhang JP, Lopez L, Braga RJ, Sevy SM, Addington J, Kellner CH (2015).

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receptor is very potent for the mitigation of bipolar conditions and also yields an antidepressant effect. The antipsychotics

1070:

Many different types of medication can induce in patients that have never had symptoms before. A new chapter about OCD in the

303:

There is very little evidence on which to base a risk and benefit assessment of using antipsychotics for long-term treatment.

20032: 12413: 12371: 11459: 10397: 9716: 9580: 8347: 6426: 6137: 1108:(FDA) required all manufacturers of atypical antipsychotics to change their labeling to include a warning about the risks of 11621: 10138:

King MV, Marsden CA, Fone KC (September 2008). "A role for the 5-HT(1A), 5-HT4 and 5-HT6 receptors in learning and memory".

9771: 2502:

receptor removes the risk for a prolonged QTc interval, but then creates a larger risk for weight gain. Relation to the 5-HT

2249:

may be a feeling of the world spinning, numbness, or muscle pains. Symptoms generally resolve after a short period of time.

16591: 7529:"Atypical antipsychotic augmentation in major depressive disorder: a meta-analysis of placebo-controlled randomized trials" 2687: 2679: 1149: 1141: 10414:"FDA : Psychopharmacological Drugs Advisory Committee : Briefing Document for ZELDOX CAPSULES (Ziprasidone HCl)" 9545: 332:

antipsychotics were marketed as offering greater efficacy in reducing psychotic symptoms while reducing side effects (and

20054: 17802: 17675: 16329: 16189: 14429: 11625: 5330:

researchers found that typical antipsychotics were no worse than atypical antipsychotics. The research was funded by the

2086: 338: 11403: 10442:

Wouters W, Tulp MT, Bevan P (May 1988). "Flesinoxan lowers blood pressure and heart rate in cats via 5-HT1A receptors".

1013:++ Standard, in terms of efficacy, treatment. No convincing evidence to say it is superior to other standard treatments. 10329: 7324: 17768: 17760: 17693: 17181: 17173: 16282: 16274: 16207: 10363: 10115: 9919: 9781: 9689: 9619: 316: 7413: 2525:

Whether the anhedonic, loss of pleasure and motivation effect resulting from dopamine insufficiency or blockade at D

1077:

There are reports that some atypical antipsychotics could cause drug-induced OCD in already schizophrenic patients.

20095: 17756: 17169: 16270: 12388: 10716: 10219: 5395: 3941:

10.7 (single 4 mg dose), 12 (single 8 mg dose), 16.2 (single 12 mg dose), 67.9 (repeated bid dosing)

584:

decreased by nearly 50%. As of now, the only FDA-approved atypical antipsychotic for alzheimer-related dementia is

134: 427:, often in conjunction with mood stabilizers (which tend to have a delayed onset of action in such cases) such as 20105: 17923: 17818: 17764: 17252: 17177: 16466: 16345: 16278: 15342: 13811: 12842: 6444:"American Geriatrics Society updated Beers Criteria for potentially inappropriate medication use in older adults" 5385: 2550: 1237:, SGAs are not associated with excess cardiovascular mortality when used to treat serious psychiatric disorders. 9753: 20072: 14447: 11322:"Do We Need a New Nomenclature for Atypical Antipsychotics? A Survey of Health Care Professionals and Patients" 5346:

Despite the name "antipsychotics", the drugs are commonly used for a variety of conditions that do not involve

1929: 219: 10646: 10292: 7570:"Drug Approvals and Databases - Drug Trials Snapshots: REXULTI for the treatment of major depressive disorder" 17846: 17230: 16387: 8932:"Efficacy and metabolic effects of lurasidone versus brexpiprazole in schizophrenia: a network meta-analysis" 7154:

Voruganti LP, Baker LK, Awad AG (March 2008). "New generation antipsychotic drugs and compliance behaviour".

7030:"Atypical antipsychotics in the treatment of schizophrenia: systematic overview and meta-regression analysis" 6586:"Treatments of Negative Symptoms in Schizophrenia: Meta-Analysis of 168 Randomized Placebo-Controlled Trials" 3964:

0.14 (single 4 mg dose), 0.45 (single 8 mg dose), 0.76 (single 12 mg dose), 0.57 (bid dosing)

2405:

receptor activity in the mesolimbic pathway, reducing or eliminating the positive symptoms of schizophrenia.

1090: 279: 11008:"Kinetics of fluphenazine after fluphenazine dihydrochloride, enanthate and decanoate administration to man" 10762:

Deeks ED, Keating GM (January 2010). "Blonanserin: a review of its use in the management of schizophrenia".

2336:

may occur, resulting in sexual dysfunction, weight gain, more rapid demineralization of bones, and possibly

1234: 20014: 19210: 18536: 17822: 16349: 14393: 11679: 11428: 5375: 2655: 1593: 1105: 576: 126: 7696:

Truven Health Analytics, Inc. DRUGDEX System (Internet) . Greenwood Village, CO: Thomsen Healthcare; 2013.

6535: 2565:

Unless otherwise specified, the drugs below serve as antagonists/inverse agonists at the receptors listed.

1104:

Recently, metabolic concerns have been of grave concern to clinicians, patients and the FDA. In 2003, the

20100: 18502: 17915: 17806: 17451: 16802: 16333: 15595: 15301: 14797: 2671: 2663: 1163: 2270:(5-HT), norepinephrine (α, β), and dopamine (DA) receptors in order to effectively treat schizophrenia. 462:(MDD), some SGAs have demonstrated significant efficacy as adjunctive agents; and, such agents include: 19883: 19458: 18721: 18297: 17889: 17546: 16951: 16440: 13716: 12817: 11615: 10814:

Borgström L, Larsson H, Molander L (1982). "Pharmacokinetics of parenteral and oral melperone in man".

7077:

Lieberman JA, Stroup TS, McEvoy JP, Swartz MS, Rosenheck RA, Perkins DO, et al. (September 2005).

2245: 11059:. 19th Annual Midyear Clinical Meeting of the American Society of Hospital Pharmacists. Dallas, Texas. 447:(trade name Latuda) has demonstrated some efficacy in the acute depressive phase of bipolar disorder. 12332: 6584:

Fusar-Poli P, Papanastasiou E, Stahl D, Rocchetti M, Carpenter W, Shergill S, McGuire P (July 2015).

6506:"Schizophrenia: Full national clinical guideline on core interventions in primary and secondary care" 5405: 5238: 2077:

Syncope (1%), pancreatitis, hypothermia, agranulocytosis, leukopenia, neutropenia, thrombocytopenia,

1474: 459: 355:

effects such as a major weight gain problem (averaging 9.4 lbs over 18 months) and increases in

166: 2288:

receptors occurs throughout the entire brain, leading to a number of deleterious side effects from D

19905: 19472: 18764: 18550: 18342: 16981: 12020: 11921: 10804:

Product Information: Eunerpan(R), Melperonhydrochlorid. Knoll Deutschland GmbH, Ludwigshafen, 1995.

10028: 8420:

Gerhard T, Huybrechts K, Olfson M, Schneeweiss S, Bobo WV, Doraiswamy PM, et al. (July 2014).

6919: 6441: 5327: 5234: 5061: 4554: 2090: 1573: 271: 130: 11576: 19652: 19218: 19055: 18540: 17962: 17281: 17130: 16495: 15670: 15355: 14896: 13235: 12376: 11784: 11672: 6633:

Murray RM, Quattrone D, Natesan S, van Os J, Nordentoft M, Howes O, et al. (November 2016).

6074: 5331: 5316: 5208: 5167: 2325: 1285: 1266: 406: 360: 333: 206:. However, only a few of the atypicals have been demonstrated to be superior to lesser-used, low- 10054: 2292:

receptor antagonism throughout the entire dopamine pathway system. It's not possible to affect D

684:? (some evidence has suggested efficacy in treating depressive symptoms in mixed/manic episodes) 19648: 19206: 19051: 18532: 18478: 17978: 17954: 17721: 17305: 17273: 17248: 16511: 16487: 16235: 16024: 15879: 15686: 15682: 15662: 15363: 15347: 14912: 14892: 13621: 12797: 12284: 12188: 12135: 12015: 11986: 11899: 11894: 11857: 11852: 10387: 9056:"Antipsychotic-associated weight gain: management strategies and impact on treatment adherence" 6635:"Should psychiatrists be more cautious about the long-term prophylactic use of antipsychotics?" 4987: 4950: 4915: 4880: 4737: 4700: 1925: 1581: 1223: 307: 207: 195: 185: 121: 10413: 10319: 10105: 9909: 9609: 7316: 7310: 19923: 19494: 19214: 18754: 18566: 18484: 18356: 17974: 17958: 17717: 17713: 17569: 17301: 17289: 17277: 16991: 16507: 16491: 16231: 16227: 15666: 15351: 13967: 13241: 12908: 12240: 11998: 11916: 11749: 11732: 11708: 10353: 10006: 9679: 8422:"Comparative mortality risks of antipsychotic medications in community-dwelling older adults" 7569: 6505: 6485: 5312: 5175: 5141: 5133: 5069: 5032: 5024: 4995: 4958: 4888: 4819: 4811: 4782: 4745: 4708: 4671: 4663: 4634: 4626: 4597: 4589: 4519: 2695: 2474: 1126: 498: 259: 181: 11236:

Weiden PJ (January 2007). "EPS profiles: the atypical antipsychotics are not all the same".

9371: 8337: 7753:

Roberts RJ, Lohano KK, El-Mallakh RS (September 2016). "Antipsychotics as antidepressants".

6534:

Aleman A, Lincoln TM, Bruggeman R, Melle I, Arends J, Arango C, Knegtering H (August 2017).

2545:

Disinhibition: The opposite process of inhibition, the turning on of a biological function.

14216: 13427: 12698: 11369: 10522:"Treatment with the 5-HT3 antagonist tropisetron modulates glucose-induced obesity in mice" 10079: 9706: 9575:(57 ed.). United Kingdom: Royal Pharmaceutical Society of Great Britain. p. 192. 7984:"Asenapine monotherapy in the acute treatment of both schizophrenia and bipolar I disorder" 5308: 5307:

The atypical antipsychotics have found favor among clinicians and are now considered to be

2599: 2591: 2583: 2575: 2332:

receptor antagonism results in elevated prolactin. If prolactin levels become high enough,

2273: 428: 275: 227: 199: 8561:"Olanzapine induced de-novo obsessive compulsive disorder in a patient with schizophrenia" 2093:(<5%), tardive dyskinesia (<5%), priapism, neuroleptic malignant syndrome (<1%), 443:

have demonstrated significant efficacy in all three treatment phases of bipolar disorder.

8: 19656: 19222: 19162: 18850: 18466: 17687: 17667: 17285: 17195: 16201: 16181: 16028: 15678: 15359: 14904: 14356: 13089: 12728: 12531: 11279:

Jones PB, Barnes TR, Davies L, Dunn G, Lloyd H, Hayhurst KP, et al. (October 2006).

11057:

Explaining the pharmacokinetics of fluphenazine through computer simulations. (Abstract.)

9054:

Dayabandara M, Hanwella R, Ratnatunga S, Seneviratne S, Suraweera C, de Silva VA (2017).

7386: 6376:

Maher AR, Maglione M, Bagley S, Suttorp M, Hu JH, Ewing B, et al. (September 2011).

6308:

Tyrer P, Kendall T (January 2009). "The spurious advance of antipsychotic drug therapy".

6007:

Note these values are from a study in of which amisulpride was intravenously administered

2333: 2078: 1876: 1601: 1271: 1118: 497:

whereas only quetiapine has demonstrated efficacy as a monotherapy in non-psychotic MDD.

9882: 19987: 19545: 19125: 18817: 17982: 17375: 17309: 16515: 14494: 12439: 11261: 11213: 11188: 11032: 11023: 11007: 10936: 10839: 10787: 10589: 10502: 10273: 10198: 9829: 9660: 9527: 9484: 9427: 9402: 9228: 9191: 9172: 9131: 9107:"M205. Long-Term Safety of Lumateperone (ITI-007): Metabolic Effects in a 1-Year Study" 9106: 9082: 9055: 9036: 9023: 8988: 8969: 8912: 8808: 8703: 8670: 8651: 8595: 8560: 8487: 8462: 8397: 8372: 8292: 8283: 8267: 8163: 8115: 8088: 8069: 8010: 7983: 7964: 7915: 7898: 7871: 7854: 7778: 7732: 7720: 7671: 7644: 7620: 7595: 7594:

Papakostas GI, Fava M, Baer L, Swee MB, Jaeger A, Bobo WV, Shelton RC (December 2015).

7504: 7477: 7291: 7179: 7005: 6981:"Increasing off-label use of antipsychotic medications in the United States, 1995-2008" 6980: 6956: 6923: 6895: 6862: 6793:

Smith T, Weston C, Lieberman J (August 2010). "Schizophrenia (maintenance treatment)".

6743: 6718: 6699: 6610: 6585: 6566: 6468: 6443: 6333: 6285: 6260: 6242: 6193: 5223: 4845: 2082: 1984: 1880: 1818: 1651: 1577: 1261: 1122: 1086: 1031: 548: 215: 10577: 9708:

Antipsychotics and Mood Stabilizers: Stahl's Essential Psychopharmacology, 3rd Edition

9005: 8631: 8243: 8218: 8087:

Szegedi A, Zhao J, van Willigenburg A, Nations KR, Mackle M, Panagides J (June 2011).

7952: 6687: 6321: 6230: 6181: 2233:

Syncope (0.6%), dysphagia (0.1–2%), bone marrow suppression, seizure (0.4%), priapism

19774: 19664: 19166: 18411: 17970: 17786: 17637: 17297: 17207: 17199: 17083: 16905: 16503: 16353: 16141: 15982: 15928: 15562: 15287: 15279: 15014: 14920: 14718: 14702: 14555: 14286: 14144: 12436: 11604: 11568: 11546:"Bioenergetic disruption of human micro-vascular endothelial cells by antipsychotics" 11351: 11343: 11302: 11253: 11249: 11218: 11150: 11115: 11111: 11080: 11037: 10985: 10940: 10883: 10879: 10831: 10779: 10775: 10624: 10581: 10543: 10494: 10459: 10455: 10393: 10359: 10325: 10265: 10202: 10190: 10155: 10111: 9915: 9864: 9821: 9777: 9712: 9685: 9652: 9648: 9615: 9576: 9519: 9515: 9488: 9476: 9472: 9432: 9233: 9176: 9164: 9087: 9040: 9028: 9010: 8961: 8953: 8904: 8853: 8800: 8762: 8708: 8690: 8671:"Clozapine-Induced Obsessive-Compulsive Symptoms in Schizophrenia: A Critical Review" 8643: 8635: 8600: 8582: 8541: 8533: 8492: 8443: 8402: 8353: 8343: 8297: 8248: 8219:"Metabolic Issues With Atypical Antipsychotics in Primary Care: Dispelling the Myths" 8155: 8120: 8061: 8015: 7956: 7920: 7876: 7770: 7724: 7676: 7625: 7550: 7509: 7455: 7320: 7283: 7214: 7171: 7136: 7100: 7059: 7054: 7029: 7010: 6961: 6943: 6900: 6882: 6843: 6802: 6775: 6748: 6703: 6691: 6656: 6615: 6558: 6473: 6459: 6422: 6399: 6325: 6290: 6234: 6185: 6143: 6133: 6130:

Kaplan & Sadock's Synopsis of Psychiatry: Behavioral Sciences/Clinical Psychiatry

6110: 2320:

receptor antagonism further compounds these problems. In the nigrostriatal pathway, D

1350: 296: 173: 11374:

Government of Canada, Health Canada, Public Affairs, Consultation and Regions Branch

11265: 10843: 10791: 10593: 10506: 10277: 9833: 9531: 8973: 8916: 8812: 8167: 8073: 7968: 7782: 7736: 6917: 6734: 6337: 6246: 2374:

receptors, thereby reducing antagonistic binding there and eliminating or lowering D

1979:

Agranulocytosis, leukopenia, neutropenia (0.3%), anaphylaxis, seizures (0.05–0.5%),

18676: 18498: 17911: 17150: 17134: 17120: 17023: 16847: 16458: 14266: 14134: 13742: 13557: 13166: 12999: 12608: 12447: 12226: 11928: 11560: 11333: 11292: 11245: 11208: 11200: 11142: 11107: 11027: 11019: 10932: 10875: 10823: 10771: 10616: 10573: 10533: 10486: 10451: 10257: 10182: 10147: 9856: 9813: 9664: 9644: 9511: 9468: 9422: 9414: 9223: 9213: 9203: 9156: 9126: 9118: 9077: 9067: 9018: 9000: 8943: 8896: 8843: 8792: 8752: 8698: 8682: 8627: 8590: 8572: 8523: 8482: 8478: 8474: 8433: 8392: 8388: 8384: 8287: 8279: 8238: 8230: 8147: 8110: 8100: 8053: 8005: 7995: 7948: 7910: 7866: 7762: 7716: 7666: 7656: 7615: 7611: 7607: 7545: 7540: 7528: 7499: 7489: 7451: 7447: 7295: 7275: 7245: 7206: 7163: 7128: 7090: 7049: 7041: 7000: 6992: 6951: 6935: 6890: 6874: 6833: 6738: 6730: 6683: 6646: 6605: 6597: 6570: 6550: 6463: 6455: 6389: 6351: 6317: 6280: 6272: 6226: 6197: 6177: 6102: 5216: 2542: 2026: 1589: 432: 267: 255: 162: 154: 44: 11595:

Simpson GM (September 2005). "Atypical antipsychotics and the burden of disease".

8832:"Consensus development conference on antipsychotic drugs and obesity and diabetes" 8655: 6442:

American Geriatrics Society 2012 Beers Criteria Update Expert Panel (April 2012).

19935: 19010: 18489: 17619: 17154: 17142: 17102: 17047: 16698: 16251: 16080: 15942: 15831: 15517: 15218: 14514: 13817: 13807: 13787: 13657: 13567: 12838: 12788: 12168: 11976: 11963: 11958: 11948: 11864: 11629: 10737: 10620: 10561: 10490: 9860: 9122: 8900: 8796: 8783:

Correll CU, Schenk EM (March 2008). "Tardive dyskinesia and new antipsychotics".

7494: 7183: 7167: 6554: 5362:

Regulatory status of second-generation antipsychotics (SGAs) as of July 2013

5272: 5220: 2631: 2623: 2615: 2607: 2412: 1754: 1411: 1296: 1179: 1171: 1133: 1056:

use of alternative psychotropic classes (e.g. antidepressants, anticonvulsants).

531:

have been approved as adjunct treatment for MDD by the FDA in the United States.

17697: 16211: 14460: 11699: 11467: 11297: 11280: 9372:"Comparison of Common Side Effects of Second Generation Atypical Antipsychotics" 9105:

Satlin A, Durgam S, Vanover KE, Davis RE, Huo J, Mates S, Correll C (May 2020).

8463:"Atypical antipsychotic use in patients with dementia: managing safety concerns" 6979:

Alexander GC, Gallagher SA, Mascola A, Moloney RM, Stafford RS (February 2011).

19931: 19927: 19560: 19498: 19140: 19061: 18885: 18832: 18474: 18448: 18438: 18430: 18360: 18114: 17573: 17401: 16995: 16573: 16435: 16068: 14547: 14502: 14119: 14094: 14059: 13983: 13832: 13562: 13522: 12848: 12783: 12405: 12382: 12010: 11906: 11832: 11817: 11564: 10151: 9418: 8757: 8740: 8686: 7476:

Spielmans GI, Berman MI, Linardatos E, Rosenlicht NZ, Perry A, Tsai AC (2013).

7132: 5268: 2647: 2639: 1403: 424: 146: 10685: 9817: 9160: 8528: 8511: 8438: 8421: 8357: 8151: 7250: 7233: 7078: 7045: 6838: 6821: 6651: 20089: 19909: 19766: 19697: 19527: 19488: 19476: 18768: 18716: 18666: 18350: 18346: 18309: 18292: 18147: 18124: 17419: 17359: 16985: 16963: 16921: 16822: 16616: 16569: 16305: 15974: 15554: 15275: 15010: 14694: 14593: 14567: 14491: 14331: 14246: 14206: 14079: 13898: 13822: 13782: 13762: 13662: 13407: 13256: 13251: 13194: 13145: 13074: 12879: 12641: 12577: 12347: 12252: 12247: 12213: 12164: 12087: 12049: 11943: 11938: 11807: 11776: 11717: 11695: 11347: 10856:

Product Information: Nipolept(R), zotepine. Klinge Pharma GmbH, Munich, 1996.

10186: 9014: 8957: 8848: 8831: 8694: 8639: 8586: 8577: 8537: 8105: 7661: 7079:"Effectiveness of antipsychotic drugs in patients with chronic schizophrenia" 6947: 6886: 6147: 5276: 5230: 3879: 2921: 2514:

receptor, which normalizes the dopamine level in the brain. This occurs with

2408: 1109: 585: 580: 516: 471: 356: 283: 251: 188: 150: 108: 11400:

Australian Government Department of Health, Therapeutic Goods Administration

10261: 8930:

Ng-Mak D, Tongbram V, Ndirangu K, Rajagopalan K, Loebel A (August 1, 2018).

6878: 6601: 2534:

between individual experience and the atypical antipsychotic(s) being used.

19953: 19939: 19913: 19808: 19798: 19709: 19689: 19642: 19583: 19480: 19393: 19378: 19363: 19310: 19294: 19190: 19115: 19082: 18900: 18782: 18696: 18544: 18376: 18212: 18207: 18167: 18119: 18073: 18057: 17907: 17701: 17501: 17351: 17211: 17146: 17053: 17039: 17011: 16999: 16941: 16892: 16882: 16852: 16832: 16807: 16752: 16723: 16713: 16668: 16636: 16624: 16620: 16604: 16549: 16215: 16135: 15985: 15858: 15656: 15640: 15574: 15390: 15369: 15336: 15291: 15153: 15098: 14998: 14722: 14639: 14585: 14575: 14341: 14336: 14321: 14241: 14201: 14175: 14170: 14129: 14124: 13973: 13918: 13908: 13873: 13863: 13792: 13752: 13712: 13672: 13647: 13637: 13627: 13577: 13552: 13547: 13517: 13472: 13276: 13271: 13231: 13084: 12914: 12894: 12884: 12828: 12813: 12803: 12718: 12310: 12235: 12218: 12183: 12110: 12105: 11981: 11971: 11953: 11884: 11869: 11847: 11822: 11812: 11789: 11608: 11572: 11355: 11306: 11257: 11222: 10783: 10628: 10585: 10547: 10498: 10269: 10194: 10159: 10107:

Antipsychotics and Mood Stabilizers: Stahl's Essential Psychopharmacology .

9868: 9825: 9773:

Antipsychotics and Mood Stabilizers: Stahl's Essential Psychopharmacology .

9656: 9480: 9436: 9237: 9168: 9091: 9032: 8965: 8908: 8857: 8804: 8766: 8712: 8647: 8604: 8545: 8496: 8447: 8406: 8371:

Dorsey ER, Rabbani A, Gallagher SA, Conti RM, Alexander GC (January 2010).

8301: 8252: 8159: 8124: 8065: 8019: 7960: 7924: 7880: 7774: 7728: 7680: 7629: 7554: 7513: 7459: 7287: 7218: 7175: 7140: 7104: 7063: 7014: 6965: 6939: 6904: 6847: 6806: 6779: 6752: 6695: 6660: 6619: 6562: 6477: 6403: 6394: 6377: 6329: 6294: 6238: 6189: 6114: 5783: 5733: 5558: 5533: 5458: 5301: 5297: 4774: 4163: 3849: 3292: 2759: 2519: 2466: 2337: 2094: 1826: 1814: 1585: 1407: 1357: 1191: 846: 648: 564: 544: 512: 466: 402: 364: 343: 320: 191: 112: 11154: 11119: 11084: 10989: 10944: 10887: 10835: 10463: 10355:

Varcarolis' Foundations of Psychiatric Mental Health Nursing: A Clinical .

9523: 8948: 8931: 8183:"Pharmacotherapy for schizophrenia: Acute and maintenance phase treatment" 7210: 2300:

receptor antagonism reverses these side effects to some extent. Reducing D

19899: 19891: 19802: 19794: 19790: 19770: 19758: 19749: 19729: 19717: 19701: 19685: 19523: 19453: 19398: 19368: 19314: 19302: 19186: 19182: 19111: 19032: 18865: 18772: 18749: 18744: 18733: 18691: 18671: 18646: 18631: 18593: 18407: 18372: 18321: 18313: 18287: 18237: 18227: 18177: 18171: 18163: 18159: 18134: 18089: 18081: 18061: 18049: 18036: 18031: 18000: 17858: 17782: 17604: 17558: 17536: 17486: 17476: 17466: 17435: 17395: 17391: 17383: 17363: 17347: 17338: 17242: 17191: 17087: 17019: 17003: 16975: 16967: 16913: 16901: 16872: 16867: 16857: 16837: 16772: 16767: 16756: 16748: 16744: 16688: 16684: 16676: 16660: 16656: 16644: 16640: 16628: 16612: 16577: 16559: 16399: 16317: 16309: 16127: 16123: 16018: 16014: 15920: 15799: 15783: 15722: 15674: 15652: 15648: 15644: 15632: 15624: 15558: 15498: 15494: 15433: 15414: 15332: 15324: 15266: 15236: 15203: 15189: 15078: 15067: 15038: 14983: 14979: 14837: 14827: 14767: 14698: 14685: 14680: 14660: 14635: 14613: 14597: 14551: 14542: 14537: 14306: 14291: 14276: 14139: 14109: 14104: 14099: 14069: 14043: 14038: 14033: 14008: 14003: 13988: 13978: 13958: 13953: 13938: 13928: 13923: 13913: 13893: 13878: 13858: 13843: 13797: 13732: 13707: 13697: 13692: 13687: 13642: 13617: 13587: 13537: 13497: 13442: 13437: 13417: 13382: 13367: 13357: 13347: 13327: 13317: 13261: 13176: 13099: 13094: 13079: 13032: 12939: 12934: 12924: 12889: 12864: 12833: 12793: 12673: 12618: 12592: 12582: 12521: 12357: 12305: 12257: 12230: 12205: 12200: 12195: 12173: 12130: 12115: 12079: 12059: 12054: 12044: 11993: 11911: 11879: 11837: 11827: 11794: 11761: 11744: 11727: 11338: 11204: 11041: 11006:

Curry SH, Whelpton R, de Schepper PJ, Vranckx S, Schiff AA (April 1979).

10961:

Reynolds JE (1993). "Anxiolytic sedatives, hypnotics and neuroleptics.".

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Schultz SH, North SW, Shields CG (June 2007). "Schizophrenia: a review".

6276: 5933: 5858: 5833: 5758: 5683: 5608: 5508: 5433: 5293: 5285: 5275:. Following research indicating its effectiveness in treatment-resistant 5109: 5098: 4345: 4273: 4203: 4013: 3933: 3815: 3563: 3400: 3076: 2973: 2867: 2705: 2515: 2462: 2436: 2192: 2034: 1992: 1887: 1758: 1609: 1597: 1482: 1419: 1307: 1290: 1281: 1199: 956: 912: 868: 758: 714: 692: 626: 560: 532: 520: 491: 476: 376: 368: 177: 116: 11664: 10520:

Weber S, Volynets V, Kanuri G, Bergheim I, Bischoff SC (December 2009).

9973:"Cariprazine - Side Effects, Uses, Dosage, Overdose, Pregnancy, Alcohol" 9218: 9072: 9053: 8217:

Kabinoff GS, Toalson PA, Healey KM, McGuire HC, Hay DP (February 2003).

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weeks to two of three different antipsychotics) in the remaining 20%.

172:

Both generations of medication tend to block receptors in the brain's

72: 19977: 19895: 19887: 19873: 19843: 19833: 19705: 19693: 19660: 19633: 19628: 19623: 19578: 19535: 19466: 19462: 19448: 19443: 19438: 19433: 19413: 19306: 19298: 19226: 19201: 19097: 19077: 19046: 18996: 18976: 18961: 18945: 18930: 18925: 18915: 18905: 18895: 18880: 18875: 18870: 18860: 18787: 18729: 18725: 18686: 18656: 18641: 18626: 18612: 18588: 18554: 18517: 18506: 18470: 18398: 18337: 18317: 18301: 18282: 18277: 18272: 18262: 18257: 18247: 18232: 18202: 18065: 18053: 18045: 17966: 17949: 17944: 17939: 17929: 17919: 17897: 17884: 17874: 17869: 17826: 17747: 17742: 17737: 17732: 17709: 17705: 17683: 17679: 17671: 17584: 17564: 17554: 17550: 17541: 17531: 17521: 17516: 17511: 17506: 17496: 17481: 17471: 17446: 17406: 17367: 17355: 17293: 17268: 17263: 17258: 17215: 17160: 17063: 17043: 17035: 17031: 16971: 16955: 16925: 16862: 16827: 16797: 16652: 16632: 16608: 16585: 16581: 16499: 16472: 16462: 16448: 16420: 16415: 16368: 16357: 16288: 16256: 16246: 16223: 16219: 16197: 16193: 16185: 16131: 16119: 16115: 16111: 16050: 16001: 15996: 15960: 15864: 15849: 15816: 15778: 15768: 15758: 15753: 15748: 15743: 15738: 15728: 15713: 15703: 15610: 15540: 15474: 15469: 15459: 15449: 15439: 15424: 15398: 15311: 15306: 15295: 15261: 15148: 15143: 15093: 15048: 15030: 15006: 14959: 14908: 14900: 14877: 14872: 14852: 14847: 14842: 14807: 14787: 14726: 14675: 14665: 14655: 14650: 14623: 14619: 14601: 14589: 14563: 14532: 14371: 14351: 14316: 14261: 14256: 14211: 14165: 14155: 13948: 13943: 13888: 13848: 13767: 13757: 13747: 13737: 13652: 13527: 13467: 13457: 13432: 13422: 13412: 13372: 13312: 13307: 13226: 13181: 13124: 13119: 13053: 13048: 13043: 13027: 12985: 12980: 12874: 12859: 12758: 12723: 12623: 12551: 12546: 12342: 12275: 12270: 12265: 12145: 12100: 12092: 12064: 12039: 12005: 11933: 11766: 7643:

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6996: 6583: 5908: 5658: 5583: 5483: 5347: 5227: 4089: 3969: 3893: 3509: 3184: 3022: 2813: 2454: 2432: 2355: 2267: 2146: 1872: 1705: 1527: 1431: 1219: 1195: 1044: 802: 736: 670: 312: 138: 98: 48: 11320:

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11069: 9972: 9677: 6127: 5319:

side effects (EPS) and an absence of sustained prolactin elevation.

1010:+ Less effective than most treatments, but still with some efficacy. 419:

In bipolar disorder, SGAs are most commonly used to rapidly control

346:, among 1,493 persons with schizophrenia. The study found that only 323:

have been recommended for the treatment of first-episode psychosis.

19973: 19969: 19947: 19943: 19754: 19733: 19598: 19519: 19502: 19196: 19174: 19158: 19107: 19028: 18758: 18651: 18572: 18522: 18512: 18403: 18368: 18364: 18332: 18139: 18093: 17986: 17798: 17774: 17727: 17600: 17423: 17411: 17313: 17187: 17138: 17125: 17079: 17015: 17007: 16936: 16728: 16708: 16692: 16554: 16519: 16325: 16293: 16241: 16171: 16107: 16103: 15978: 15970: 15924: 15916: 15854: 15812: 15808: 15804: 15718: 15615: 15585: 15550: 15502: 15490: 15429: 15271: 15251: 15246: 15199: 15063: 15053: 15034: 14944: 14934: 14924: 14857: 14777: 14757: 14732: 14710: 14690: 14670: 14631: 14361: 14196: 14114: 14048: 13727: 13702: 13677: 13667: 13377: 13362: 13292: 13202: 13140: 13135: 13109: 12960: 12944: 12808: 12649: 12541: 12505: 12470: 12295: 12125: 12074: 11874: 11799: 11756: 10654: 10296: 7705: 7642: 7475: 7264: 6261:"A roadmap to key pharmacologic principles in using antipsychotics" 5958: 5246: 5180: 5146: 5037: 4676: 4639: 4385: 3617: 1980: 1868: 1346: 1113: 1052: 978: 263: 235: 231: 11489: 11319: 10386:

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8510:

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7027: 6820:

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6819: 2488:

receptor is linked to weight gain. To have partial agonism at the

2446:

receptor antagonists improve cognition, learning, and memory. The

19744: 19638: 19593: 19484: 19343: 19338: 19333: 19328: 19254: 18739: 18603: 18562: 18327: 18252: 18005: 17814: 17661: 17579: 16887: 16817: 16787: 16341: 16176: 16165: 16099: 16006: 15869: 15620: 15316: 15128: 15118: 15108: 14867: 14862: 14752: 14226: 14064: 13853: 13682: 13452: 13302: 13297: 13266: 12668: 12567: 12562: 11889: 11616:

New antipsychotic drugs carry risks for children (USA Today 2006)

8929: 8509: 6515:. National Collaborating Centre for Mental Health. March 25, 2009 5242: 1399: 1085:

All of the atypical antipsychotics warn about the possibility of

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Pharmacokinetic parameters of available atypical antipsychotics

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alongside an antipsychotic significantly reduces weight gain.

62:

Second generation antipsychotic, serotonin–dopamine antagonist

19613: 19608: 18855: 18776: 16477: 16430: 14812: 14186: 13287: 10690: 10080:"REXULTI (brexpiprazole) | Important Safety Information" 9403:"Antipsychotic-induced sexual dysfunction and its management" 8986: 8331: 6215: 4926: 4856: 4787: 4565: 4530: 2496: 2447: 2440: 2309: 2305: 1071: 420: 326: 11193:

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8875:(12th ed.). McGraw Hill Professional. pp. 417–455. 8329: 8327: 8325: 8323: 8321: 8319: 8317: 8315: 8313: 8311: 8223:

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6132:(11th ed.). Philadelphia: Wolters Kluwer. p. 318. 1987:(0.1–5%), suicidal ideation, pancreatitis, syncope (0.3–1%) 39: 19242: 17850: 17649: 17645: 17641: 17234: 16391: 16153: 16149: 16145: 15113: 10519: 9678:

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8370: 8268:"Side effects of atypical antipsychotics: a brief overview" 7896: 7117: 7076: 6860: 6533: 5998:

route of administration when being used as an antipsychotic

3832:

Urine (50%), faeces (20%; 70% of this is as unchanged drug)

7384: 7199:

The International Journal of Risk & Safety in Medicine

6375: 5267:

The first major tranquilizer or antipsychotic medication,

19602: 19178: 19040: 17810: 17752: 17165: 16337: 16266: 15570: 14714: 13114: 11622:"NIMH Study to Guide Treatment Choices for Schizophrenia" 11054: 10975: 10250:

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9611:

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9570: 8559:

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8558: 8308: 8043: 5300:

following in the early 2000s. The atypical antipsychotic

4470:

Pharmacokinetics of long-acting injectable antipsychotics

1190:

lurasidone, and ziprasidone the most benign parameters.

1178:

in the metabolic effects of atypical antipsychotics. The

10813: 9803: 9607: 9571:

Joint Formulary Committee B, ed. (March 2009). "4.2.1".

9501: 9104: 6419:

Persecutory delusions: assessment, theory, and treatment

111:

drugs (antipsychotic drugs in general are also known as

10476: 10385: 9738: 9736: 9734: 9732: 9730: 9728: 7752: 7387:"Bipolar Affective Disorder Treatment & Management" 6167: 2029:

risk which is what led to its removal from the market.

567:

have received FDA approval for irritability in autism.

11167: 10351: 9189: 8870: 7593: 1249:

Comparison of side effects for atypical antipsychotics

1240: 11519:

Medicines & Healthcare products Regulatory Agency

11278: 10900: 10865: 9684:. Springer Science & Business Media. p. 85. 8885: 7852: 6092: 1817:, immune hypersensitivity reaction, seizures (0.9%), 1572:

Seizures (3–5%), agranulocytosis (1.3%), leukopenia,

1066:

Obsessive–compulsive disorder § Drug-induced OCD

11161: 11048: 10894: 10172: 9725: 8516:

The International Journal of Neuropsychopharmacology

6928:

The International Journal of Neuropsychopharmacology

6792: 6416: 6128:

Sadock BJ, Sadock, Virginia A., Ruiz, Pedro (2014).

250:

Atypical antipsychotics are typically used to treat

11553:

Biochemical and Biophysical Research Communications

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Medicines and Healthcare products Regulatory Agency

7414:"Bipolar Disorder in adults: Maintenance treatment" 6765: 1696:Agranulocytosis, seizures (<1%), elevated serum 1074:(2013) now specifically includes drug-induced OCD. 570: 10214: 10212: 9370: 8181:Stroup TS, Marder S, Stein MB (October 23, 2013). 7153: 6674:van Os J, Kapur S (August 2009). "Schizophrenia". 5311:for schizophrenia and are gradually replacing the 4106:Urine (70% as metabolites; 5–10.4% unchanged drug) 2296:receptors only in the mesolimbic pathway, but 5-HT 579:requires that all atypical antipsychotics carry a 119:, although the latter is usually reserved for the 14490: 9145: 8460: 8342:(6th ed.). Prentice Hall. pp. 241–260. 8180: 6421:. Oxford : Oxford University Press. p. 313. 6356:The American Society of Health-System Pharmacists 1159:receptor at therapeutic-relevant concentrations. 20087: 12435: 10956: 10954: 10441: 10103: 9769: 9608:Haddad P, Haddad PM, Dursun S, Deakin B (2004). 7526: 7369: 3977:8 hours (single dosing), 12 (twice daily dosing) 210:first-generation antipsychotics in this regard. 10918: 10916: 10209: 10137: 9846: 9458: 9396: 9394: 8826: 8824: 8822: 8734: 8732: 8730: 8728: 8726: 8724: 8722: 8512:"Obsessive-compulsive symptoms with olanzapine" 8212: 8210: 8208: 8206: 8204: 7892: 7890: 7855:"Use of atypical antipsychotics in the elderly" 7853:Cascade E, Kalali AH, Cummings JL (July 2008). 7848: 7846: 7844: 7842: 7748: 7746: 7471: 7469: 2266:The atypical antipsychotics integrate with the 591: 11001: 10999: 10922: 10713:"Therapeutic Goods Administration – Home page" 10653:. University of North Carolina. Archived from 9564: 9459:Onrust SV, McClellan K (2001). "Perospirone". 8741:"Atypical antipsychotics: mechanism of action" 8668: 6095:Clinical Schizophrenia & Related Psychoses 3841:Two peaks: 1 hr & 3-4 hrs post-oral dosing 16898:Serotonin antagonists and reuptake inhibitors 14476: 12421: 11680: 11272: 11229: 11180: 11097: 10951: 10166: 10131: 8936:Journal of Comparative Effectiveness Research 8782: 8174: 7981: 6513:Gaskell and the British Psychological Society 6211: 6209: 6207: 4455: 4436:- maximum plasma concentrations of the drug. 2480:receptor also has an antidepressant effect. H 1039:different factors such as lifestyle or diet. 13167:Deoxyepinephrine (N-methyldopamine, epinine) 12609:Deoxyepinephrine (N-methyldopamine, epinine) 11543: 11326:The Primary Care Companion for CNS Disorders 11126: 11091: 11063: 10969: 10925:Acta Psychiatrica Scandinavica. Supplementum 10913: 10761: 10317: 9840: 9681:Adherence to Antipsychotics in Schizophrenia 9391: 8819: 8719: 8201: 7887: 7839: 7743: 7466: 7405: 6626: 6307: 643:? (+++ as a dysthymia monotherapy, however) 450: 10996: 10560: 9365: 9363: 9361: 9359: 9357: 9355: 9353: 9351: 9349: 9347: 9345: 9343: 9341: 9339: 9337: 9335: 9333: 9331: 9329: 9327: 9325: 9323: 9321: 9319: 9317: 9315: 9313: 9311: 9309: 9307: 9305: 9303: 9301: 9299: 9297: 9295: 9293: 9291: 9289: 9287: 9285: 9283: 9281: 9279: 9277: 9275: 9273: 9271: 9269: 9267: 8461:Steinberg M, Lyketsos CG (September 2012). 7527:Nelson JC, Papakostas GI (September 2009). 7444:The Cochrane Database of Systematic Reviews 7365: 7363: 7361: 6716: 6673: 6490:: CS1 maint: numeric names: authors list ( 315:is considered a first choice treatment for 14483: 14469: 12428: 12414: 11687: 11673: 11464:Pharmaceuticals and Medical Devices Agency 10755: 10651:Psychoactive Drug Screening Program (PDSP) 9907: 9603: 9601: 9599: 9597: 9595: 9400: 9265: 9263: 9261: 9259: 9257: 9255: 9253: 9251: 9249: 9247: 8265: 8137: 7975: 7822:"DailyMed - CAPLYTA- lumateperone capsule" 6719:"Pharmacologic treatment of schizophrenia" 6577: 6448:Journal of the American Geriatrics Society 6417:Garety PA, Freeman DB, Bentall RP (2008). 6204: 4462: 4448: 838:+++/++ (+++ when combined with fluoxetine) 547:have been approved, as monotherapies, for 327:Efficacy in the treatment of schizophrenia 38: 11694: 11337: 11296: 11212: 11031: 10816:European Journal of Clinical Pharmacology 10537: 10352:Margaret Jordan Halter (March 12, 2014). 10110:Cambridge University Press. p. 172. 9776:Cambridge University Press. p. 105. 9634: 9454: 9452: 9450: 9448: 9446: 9426: 9227: 9217: 9207: 9130: 9081: 9071: 9022: 9004: 8947: 8871:Brunton L, Chabner B, Knollman B (2010). 8847: 8756: 8702: 8594: 8576: 8527: 8486: 8437: 8396: 8291: 8242: 8114: 8104: 8009: 7999: 7914: 7870: 7670: 7660: 7619: 7544: 7503: 7493: 7249: 7094: 7053: 7004: 6955: 6894: 6837: 6742: 6650: 6609: 6467: 6393: 6284: 258:. They are also frequently used to treat 51:, the first atypical antipsychotic (1972) 11189:"Atypicality of atypical antipsychotics" 11012:British Journal of Clinical Pharmacology 10960: 9911:Diabetic Neuropathy: Clinical Management 9401:Park YW, Kim Y, Lee JH (December 2012). 7520: 7411: 7358: 7308: 6667: 6163: 6161: 6159: 6157: 4112:65% (tablet), 87% (IM), 54% (oral syrup) 2473:receptor. Antagonistic affinity for the 2392:antagonistic agent particles occupy 5-HT 2280:: Hyperactive dopaminergic activity on D 14056:Antiemetics/gastroprokinetics/sedatives 11594: 11490:"Medicines Information: SPC & PILs" 11423: 11421: 10641: 10324:Elsevier Health Sciences. p. 209. 9752:. University Psychiatry. Archived from 9592: 9244: 8778: 8776: 7437: 7435: 1162:Recent evidence suggests a role of the 20088: 11235: 10606: 10358:Elsevier Health Sciences. p. 61. 10029:"Diabetes Update: Hunger is a Symptom" 9908:Veves A, Malik RA (February 1, 2008). 9443: 8738: 8669:Schirmbeck F, Zink M (March 1, 2012). 8364: 8039: 8037: 8035: 8033: 8031: 8029: 7988:Neuropsychiatric Disease and Treatment 7709:Journal of Clinical Psychopharmacology 5337: 5304:was approved by the FDA in late 2006. 14464: 12409: 11668: 11186: 10686:"Medscape Multispecialty – Home page" 9704: 8335: 7692: 7690: 7231: 6813: 6786: 6759: 6498: 6154: 6086: 6057: 6055: 6053: 6051: 6041: 6039: 6037: 6027: 6025: 4278:Oral, intramuscular (including depot) 4168:Oral, intramuscular (including depot) 4128:Oral, intramuscular (including depot) 3854:Oral, intramuscular (including depot) 1080: 621:Adjunct in Major Depressive Disorder 18412:methylergometrine (methylergonovine) 17372:N-desalkylquetiapine (norquetiapine) 17208:methylergometrine (methylergonovine) 16354:methylergometrine (methylergonovine) 15983:methylergometrine (methylergonovine) 15929:methylergometrine (methylergonovine) 15288:methylergometrine (methylergonovine) 14719:methylergometrine (methylergonovine) 11628:. September 19, 2005. Archived from 11597:The American Journal of Managed Care 11418: 11370:"Drug Product Database Online Query" 8773: 7567: 7432: 6985:Pharmacoepidemiology and Drug Safety 6369: 5353: 1089:in their package inserts and in the 501:is an efficacious treatment in both 17376:N-desmethylclozapine (norclozapine) 13658:Levomepromazine (methotrimeprazine) 11865:Levomepromazine (methotrimeprazine) 11626:National Institute of Mental Health 11515:"Guidance: Antipsychotic medicines" 11429:"European Medicines Agency: Search" 10963:Martindale: The Extra Pharmacopoeia 10220:"Pharmcology Reviews : 200603" 10104:Stephen M. Stahl (March 27, 2008). 9770:Stephen M. Stahl (March 27, 2008). 8026: 7372:The Maudsley Prescribing Guidelines 7370:Taylor D, Paton C, Kapur S (2012). 7083:The New England Journal of Medicine 6344: 4424:IR - Immediate release formulation. 3752: 2358:is released on to postsynaptic 5-HT 2261: 2087:thrombotic thrombocytopenic purpura 1241:Comparison table of adverse effects 1059: 414: 13: 11536: 11024:10.1111/j.1365-2125.1979.tb00941.x 10978:The Journal of Clinical Psychiatry 10937:10.1111/j.1600-0447.1980.tb07082.x 10140:Trends in Pharmacological Sciences 8864: 8467:The American Journal of Psychiatry 8336:McKim W (2007). "Antipsychotics". 8284:10.1002/j.2051-5545.2008.tb00154.x 8266:Uçok A, Gaebel W (February 2008). 7721:10.1097/01.jcp.0000130557.08996.7a 7687: 7600:The American Journal of Psychiatry 7533:The American Journal of Psychiatry 7121:The American Journal of Psychiatry 6723:Dialogues in Clinical Neuroscience 6048: 6034: 6022: 4426:XR - Extended release formulation. 2556: 2239: 1024: 14: 20117: 11646: 10742:U.S. National Library of Medicine 9742: 9407:The World Journal of Men's Health 8426:The British Journal of Psychiatry 7412:Post RM, Keck P (July 30, 2013). 7238:Advances in Psychiatric Treatment 6826:The British Journal of Psychiatry 6639:The British Journal of Psychiatry 317:treatment resistant schizophrenia 176:. Atypicals are less likely than 11652: 11544:Elmorsy E, Smith PA (May 2015). 11507: 11482: 11452: 11388: 11362: 11313: 11250:10.1097/00131746-200701000-00003 11135:International Pharmacopsychiatry 11112:10.2165/00003495-198733010-00002 10880:10.1097/00007691-199802000-00021 10859: 10850: 10807: 10798: 10776:10.2165/11202620-000000000-00000 10730: 10717:Department of Health (Australia) 10705: 10678: 10669: 10635: 10609:European Journal of Pharmacology 10600: 10566:European Neuropsychopharmacology 10554: 10526:International Journal of Obesity 10513: 10470: 10444:European Journal of Pharmacology 10435: 10406: 10379: 10345: 10311: 10284: 10240: 10097: 9943:"Epinephrine and Norepinephrine" 9849:European Journal of Pharmacology 9649:10.1111/j.1600-0447.2006.00787.x 9614:. OUP Oxford. pp. 207–216. 9516:10.2165/00002018-199308060-00005 9473:10.2165/00023210-200115040-00006 8620:European Neuropsychopharmacology 6460:10.1111/j.1532-5415.2012.03923.x 6001: 5991: 1477:, angioedema, suicidal ideation 1475:Immune hypersensitivity reaction 571:Dementia and Alzheimer's disease 289: 90:second generation antipsychotics 20064:Monoamine metabolism modulators 14439:Monoamine metabolism modulators 11238:Journal of Psychiatric Practice 10072: 10047: 10021: 9991: 9965: 9935: 9901: 9875: 9797: 9763: 9698: 9671: 9628: 9538: 9495: 9183: 9139: 9098: 9047: 8980: 8923: 8879: 8662: 8611: 8552: 8503: 8454: 8413: 8259: 8131: 8080: 7931: 7814: 7789: 7699: 7636: 7587: 7561: 7378: 7333: 7302: 7258: 7225: 7190: 7147: 7111: 7070: 7021: 6972: 6911: 6854: 6710: 6527: 6435: 4755:12.5–100 mg/1–4 weeks 4718:12.5–100 mg/2–5 weeks 4535:441–1064 mg/4–8 weeks 4030:Urine (45-58%), faeces (20-22%) 3922:35% (sublingual), <2% (Oral) 2551:Downregulation and Upregulation 2324:receptor antagonism results in 2256: 1815:Acute haemorrhagic pancreatitis 245: 218:(a serious movement disorder), 11285:Archives of General Psychiatry 10005:. May 17, 2016. Archived from 9711:. Cambridge University Press. 9637:Acta Psychiatrica Scandinavica 8745:Canadian Journal of Psychiatry 8565:Indian Journal of Pharmacology 8479:10.1176/appi.ajp.2012.12030342 8389:10.1001/archinternmed.2009.456 8046:Acta Psychiatrica Scandinavica 7612:10.1176/appi.ajp.2015.14101251 7546:10.1176/appi.ajp.2009.09030312 7452:10.1002/14651858.CD008121.pub2 6410: 6301: 6253: 6121: 4931:39–819 mg/4–12 weeks 4861:150–405 mg/2–4 weeks 4220:Urine (0.4% as unchanged drug) 3797:Enzymes involved in metabolism 1930:neuroleptic malignant syndrome 1650:Suicidal ideation (0.4–1.1%), 220:neuroleptic malignant syndrome 1: 20051:Monoamine reuptake inhibitors 20015:Receptor/signaling modulators 14421:Monoamine reuptake inhibitors 14394:Receptor/signaling modulators 12573:Adrogolide (ABT-431, DAS-431) 10578:10.1016/S0924-977X(99)00055-3 10318:Hemmings HC, Egan TD (2013). 10175:Journal of Psychopharmacology 9467:(4): 329–37, discussion 338. 9149:Journal of Psychopharmacology 9006:10.1016/S2215-0366(19)30416-X 8842:(2): 596–601. February 2004. 8785:Current Opinion in Psychiatry 8632:10.1016/s0924-977x(00)00096-1 8377:Archives of Internal Medicine 7953:10.1016/S0140-6736(11)60873-8 7156:Current Opinion in Psychiatry 6735:10.31887/DCNS.2010.12.3/jkane 6688:10.1016/S0140-6736(09)60995-8 6322:10.1016/S0140-6736(08)61765-1 6231:10.1016/S0140-6736(13)60733-3 6182:10.1016/S0140-6736(08)61764-X 6080: 5185:50–800 mg/2–4 weeks 4968:50–200 mg/2–4 weeks 4829:20–400 mg/2–4 weeks 4681:10–200 mg/2–4 weeks 4644:50–600 mg/1–4 weeks 4281:3 (EM) (oral), 20 (PM) (oral) 3857:75 (94 for active metabolite) 1867:Agranulocytosis, leukopenia, 1821:, suicidal ideation (0.1–1%) 1099: 367:. No other atypical studied ( 280:obsessive-compulsive disorder 194:in patients such as unsteady 16:Class of pharmaceutical drugs 11170:Current Therapeutic Research 10903:Current Therapeutic Research 10621:10.1016/j.ejphar.2013.08.048 10491:10.1016/j.autneu.2008.06.004 10456:10.1016/0014-2999(88)90651-6 10055:"High & Low Blood Sugar" 9861:10.1016/j.ejphar.2005.09.065 8901:10.1016/j.schres.2013.02.023 8797:10.1097/YCO.0b013e3282f53132 7982:Bishara D, Taylor D (2009). 7495:10.1371/journal.pmed.1001403 7168:10.1097/YCO.0b013e3282f52851 6717:Kane JM, Correll CU (2010). 6555:10.1016/j.schres.2016.05.015 5151:50–200 mg/1–3 days 5114:12.5–75 mg/2 weeks 5079:100–200 mg/2 weeks 4570:300–400 mg/4 weeks 4428:EM - Extensive metabolisers. 3844:39±3 (1 hr), 54±4 (3-4 hrs) 1106:Food and Drug Administration 592:Comparison table of efficacy 577:Food and Drug Administration 180:—the most widely used 7: 19884:Tetracyclic antidepressants 19459:Tetracyclic antidepressants 18722:Tetracyclic antidepressants 18298:Tetracyclic antidepressants 17547:Tetracyclic antidepressants 16952:Tetracyclic antidepressants 11298:10.1001/archpsyc.63.10.1079 10868:Therapeutic Drug Monitoring 9705:Stahl SM (March 27, 2008). 6068: 5042:25–400 mg/4 weeks 5005:25–200 mg/2 weeks 4607:40–300 mg/4 weeks 4326:Urine (4%), faeces (46-56%) 2469:are very potent at the 5-HT 10: 20122: 14430:Monoamine releasing agents 13618:Flupentixol (flupenthixol) 12794:Flupentixol (flupenthixol) 12333:Monoamine-depleting agents 11828:Carphenazine (carfenazine) 11565:10.1016/j.bbrc.2015.03.122 10152:10.1016/j.tips.2008.07.001 10033:Diabetesupdate.blogspot.se 9746:Antipsychotics Explained 1 9573:British National Formulary 9419:10.5534/wjmh.2012.30.3.153 9123:10.1093/schbul/sbaa030.517 8758:10.1177/070674370204700106 8739:Seeman P (February 2002). 8687:10.2174/157015912799362724 7133:10.1176/appi.ajp.163.4.611 5360: 5262: 5239:medium-chain triglycerides 5203: 4418: 3774:Route(s) of Administration 3763: 2246:British National Formulary 1247: 1063: 20005: 19962: 19906:Tricyclic antidepressants 19824:Metitepine (methiothepin) 19674: 19571: 19559: 19512: 19473:Tricyclic antidepressants 19404:Metitepine (methiothepin) 19278: 19151: 19139: 19088:Metitepine (methiothepin) 19070: 19021: 19009: 18954: 18843: 18831: 18801: 18581: 18459: 18447: 18429: 18391: 18343:Tricyclic antidepressants 18218:Metitepine (methiothepin) 18024: 17630: 17618: 17593: 17462:Metitepine (methiothepin) 17331: 17113: 17101: 17072: 16982:Tricyclic antidepressants 16813:Metitepine (methiothepin) 16537: 16091: 16079: 16067: 16046:Metitepine (methiothepin) 16038: 15953: 15941: 15909: 15901:Metitepine (methiothepin) 15893: 15842: 15830: 15792: 15764:Metitepine (methiothepin) 15696: 15528: 15516: 15483: 15455:Metitepine (methiothepin) 15378: 15229: 15217: 15182: 15104:Metitepine (methiothepin) 14968: 14525: 14513: 14501: 14384: 14282:Metitepine (methiothepin) 13708:Pericyazine (periciazine) 13506: 13132:Dihydrexidine derivatives 13011: 12998: 12971:Metitepine (methiothepin) 12767: 12737: 12559:Dihydrexidine derivatives 12459: 12446: 12366: 12324: 12154: 12031: 11707: 11433:European Medicines Agency 10392:. John Wiley & Sons. 9914:. Springer. p. 401. 9818:10.1007/s00213-008-1226-4 9161:10.1177/02698811211035391 8675:Current Neuropharmacology 8529:10.1017/S1461145704004456 8439:10.1192/bjp.bp.112.122499 8152:10.1007/s40263-013-0085-7 7251:10.1192/apt.bp.107.003970 7046:10.1136/bmj.321.7273.1371 6839:10.1192/bjp.bp.115.177261 6795:American Family Physician 6768:American Family Physician 6652:10.1192/bjp.bp.116.182683 5156: 4834: 4362:Faeces (66%), urine (20%) 4290:Urine (70%), faeces (14%) 4254:Urine (73%), faeces (20%) 4180:Urine (80%), faeces (11%) 4140:Urine (57%), faeces (30%) 4118:75–324 (repeated dosing) 3986:Urine (50%), faeces (30%) 3950:Urine (59%), faeces (30%) 3910:Urine (50%), faeces (40%) 3866:Faeces (55%), urine (25%) 3784:Volume of distribution (V 3690:Clinically Insignificant 1604:and abnormal peristalsis 999: 600:Relative efficacy of SGAs 598: 554: 460:major depressive disorder 451:Major depressive disorder 167:major depressive disorder 71: 66: 56: 37: 28: 23: 19394:Latrepirdine (dimebolin) 19083:Latrepirdine (dimebolin) 18408:ergometrine (ergonovine) 18208:Latrepirdine (dimebolin) 17605:ergometrine (ergonovine) 16318:ergometrine (ergonovine) 15921:ergometrine (ergonovine) 15499:ergometrine (ergonovine) 15204:ergometrine (ergonovine) 13884:Clotiapine (clothiapine) 13758:Spiperone (spiroperidol) 13723:Piflutixol (pifluthixol) 12021:Zuclopenthixol decanoate 11922:Pipotiazine undecylenate 11785:Diphenylbutylpiperidines 11396:"Search the TGA website" 10389:Psychiatry, 2 Volume Set 10187:10.1177/0269881107082944 9060:Neuropsychiatr Dis Treat 8849:10.2337/diacare.27.2.596 8578:10.4103/0253-7613.100406 8106:10.1186/1471-244X-11-101 7662:10.1186/1471-244X-12-160 6641:(Submitted manuscript). 5984: 5235:fractionated coconut oil 5062:Pipotiazine undecylenate 4792:2–12 mg/1 week 4555:Aripiprazole monohydrate 4430:PM - Poor metabolisers. 4070:Faeces (80%), urine (9%) 2537: 2370:antagonistic action at D 2091:cerebrovascular incident 1594:Stevens–Johnson syndrome 1233:Despite increasing some 272:autism spectrum disorder 222:, and increased risk of 20096:Atypical antipsychotics 19682:Atypical antipsychotics 19291:Atypical antipsychotics 18609:Atypical antipsychotics 18042:Atypical antipsychotics 17344:Atypical antipsychotics 16597:Atypical antipsychotics 14976:Atypical antipsychotics 14582:Atypical antipsychotics 13840:Atypical antipsychotics 13223:Atypical antipsychotics 13156:N,N-Propyldihydrexidine 12856:Atypical antipsychotics 12745:Tetrahydroisoquinolines 12006:Tiotixene (thiothixene) 11659:Atypical antipsychotics 10738:"Daily Med – Home page" 10262:10.1124/jpet.110.167346 9379:. Wolters Kluwer Health 9377:Facts & Comparisons 7755:Asia-Pacific Psychiatry 7420:. Wolters Kluwer Health 6075:List of antidepressants 5332:National Health Service 5209:intramuscular injection 5168:Zuclopentixol decanoate 3682:No Affinity or No Data 2326:extrapyramidal symptoms 1924:Insomnia in up to 23%, 1224:GLP-1 receptor agonists 334:extrapyramidal symptoms 240:Significant weight gain 82:atypical antipsychotics 20106:Treatment of psychosis 19924:Typical antipsychotics 19495:Typical antipsychotics 18755:Typical antipsychotics 18637:Bemesetron (MDL-72222) 18357:Typical antipsychotics 17570:Typical antipsychotics 16992:Typical antipsychotics 15683:5-(nonyloxy)tryptamine 13514:Typical antipsychotics 12775:Typical antipsychotics 12189:Paliperidone palmitate 12136:Oxyprothepin decanoate 12016:Zuclopenthixol acetate 11987:Clopenthixol decanoate 11900:Perphenazine enanthate 11895:Perphenazine decanoate 11858:Fluphenazine enanthate 11853:Fluphenazine decanoate 11073:Arzneimittel-Forschung 10479:Autonomic Neuroscience 8889:Schizophrenia Research 7312:Anatomy of an Epidemic 6867:Schizophrenia Bulletin 6590:Schizophrenia Bulletin 6543:Schizophrenia Research 6395:10.1001/jama.2011.1360 5313:typical antipsychotics 5292:were introduced, with 5241:). = Predicted, from 4988:Perphenazine enanthate 4951:Perphenazine decanoate 4916:Paliperidone palmitate 4881:Oxyprothepin decanoate 4738:Fluphenazine enanthate 4701:Fluphenazine decanoate 1582:angle-closure glaucoma 1302:Other adverse effects 412: 198:–type movements, body 122:typical antipsychotics 24:Atypical antipsychotic 20073:Monoamine neurotoxins 17851:MDMA (midomafetamine) 17235:MDMA (midomafetamine) 16838:Opiranserin (VVZ-149) 16392:MDMA (midomafetamine) 16098:25H/NB series (e.g., 14448:Monoamine neurotoxins 13242:Aripiprazole lauroxil 12241:Aripiprazole lauroxil 11999:Flupentixol decanoate 11917:Pipotiazine palmitate 11750:Haloperidol decanoate 11733:Bromperidol decanoate 10293:"PDSP Database - UNC" 8993:The Lancet Psychiatry 8949:10.2217/cer-2018-0016 7211:10.3233/JRS-2012-0567 6879:10.1093/schbul/sbv125 6602:10.1093/schbul/sbu170 6016:Stahl: AP Explained 1 5328:Manchester University 5309:first-line treatments 5134:Zuclopentixol acetate 5025:Pipotiazine palmitate 4812:Haloperidol decanoate 4664:Flupentixol decanoate 4627:Clopentixol decanoate 4590:Bromperidol decanoate 4520:Aripiprazole lauroxil 4374:60% (Oral), 100% (IM) 4287:90%, 77% (metabolite) 2388:antagonism. When 5-HT 1422:, suicidal ideation, 1398:Seizures (0.1–0.3%), 499:Olanzapine/fluoxetine 398: 182:typical antipsychotic 101:–dopamine antagonists 18545:bufotenidine (5-HTQ) 17668:5-Methoxytryptamines 16182:5-Methoxytryptamines 14217:Desmethoxyfallypride 13428:Propylnorapomorphine 13227:Alentemol (U-66444B) 12699:Propylnorapomorphine 11661:at Wikimedia Commons 11632:on September 2, 2013 11603:(8 Suppl): S235-41. 11470:on November 16, 2018 11339:10.4088/PCC.22m03331 11205:10.4088/PCC.v07n0602 10539:10.1038/ijo.2009.191 9979:. September 17, 2015 9759:on November 7, 2017. 8235:10.4088/PCC.v05n0103 7826:dailymed.nlm.nih.gov 7096:10.1056/NEJMoa051688 6940:10.1093/ijnp/pyaa004 6277:10.4088/PCC.v09n0607 3803:Peak plasma time (h) 3746:Cloned Rat Receptor 276:persecutory delusion 228:sudden cardiac death 19163:dihydroergocryptine 17847:MDA (tenamfetamine) 17231:MDA (tenamfetamine) 17196:dihydroergocryptine 16388:MDA (tenamfetamine) 14357:Tetrahydropalmatine 13090:Dihydroergocryptine 12729:Tetrahydropalmatine 12532:Dihydroergocryptine 10657:on November 8, 2013 10299:on November 8, 2013 9953:on October 13, 2016 9889:. December 15, 2010 9073:10.2147/NDT.S113099 7309:Whitaker R (2010). 6271:(6): 444–54. 2007. 5338:Society and culture 4472: 4350:Oral, intramuscular 4094:Oral, intramuscular 3730:Exceptionally High 2431:receptor increases 2334:hyperprolactinaemia 2079:hyperprolactinaemia 2025:There is a risk of 1877:hyperprolactinaemia 1602:erythema multiforme 1119:insulin sensitivity 615:Bipolar Maintenance 196:Parkinson's disease 20101:Psychopharmacology 19988:naphthylpiperazine 19759:2-Br-LSD (BOL-148) 19546:naphthylpiperazine 19524:2-Br-LSD (BOL-148) 19126:naphthylpiperazine 19033:2-Br-LSD (BOL-148) 18818:naphthylpiperazine 17694:α-Alkyltryptamines 16208:α-Alkyltryptamines 14492:Serotonin receptor 12393:Never to phase III 10828:10.1007/BF00545974 10647:"PDSP Ki Database" 10227:Accessdata.fda.gov 10009:on August 17, 2016 9806:Psychopharmacology 8058:10.1111/acps.12343 7767:10.1111/appy.12186 7391:Medscape Reference 7268:Neuropsychobiology 6922:(April 23, 2020). 6107:10.3371/CSRP.6.3.4 5224:aqueous suspension 4992:Trilafon Enanthate 4846:Olanzapine pamoate 4742:Prolixin Enanthate 4705:Prolixin Decanoate 4443: 4097:3–4 (oral), 6 (IM) 3878:87% (Oral), 100% ( 2083:sexual dysfunction 1985:tardive dyskinesia 1881:sexual dysfunction 1819:status epilepticus 1578:respiratory arrest 1123:insulin resistance 1087:tardive dyskinesia 1081:Tardive dyskinesia 1032:tardive dyskinesia 618:Bipolar Depression 549:bipolar depression 407:receptor occupancy 351:relatively severe 216:tardive dyskinesia 202:, and involuntary 157:, irritability in 107:), are a group of 20083: 20082: 20076: 20067: 20058: 20045: 20036: 20027: 20018: 20001: 20000: 19997: 19996: 19967:Unknown/unsorted: 19775:dihydroergotamine 19555: 19554: 19517:Unknown/unsorted: 19167:dihydroergotamine 19135: 19134: 19105:Unknown/unsorted: 19005: 19004: 18827: 18826: 18806:Unknown/unsorted: 18475:ethanol (alcohol) 18425: 18424: 18421: 18420: 18396:Unknown/unsorted: 17787:dihydroergotamine 17614: 17613: 17598:Unknown/unsorted: 17200:dihydroergotamine 17097: 17096: 17084:dihydroergotamine 17077:Unknown/unsorted: 16906:hydroxynefazodone 16063: 16062: 16059: 16058: 15937: 15936: 15914:Unknown/unsorted: 15826: 15825: 15797:Unknown/unsorted: 15563:dihydroergotamine 15512: 15511: 15488:Unknown/unsorted: 15280:dihydroergotamine 15213: 15212: 15187:Unknown/unsorted: 15015:iodocyanopindolol 14703:dihydroergotamine 14556:hydroxynefazodone 14458: 14457: 14451: 14442: 14433: 14424: 14415: 14406: 14397: 14380: 14379: 14287:N-Methylspiperone 14145:Trimethobenzamide 13205: 13197: 13189: 12994: 12993: 12652: 12644: 12631: 12437:Dopamine receptor 12403: 12402: 12227:Phenylpiperazines 11657:Media related to 11624:(Press release). 11521:. August 25, 2005 11147:10.1159/000468580 10399:978-1-118-84547-9 10059:Healthvermont.gov 9718:978-0-521-88664-2 9582:978-0-85369-845-6 9209:10.1111/bdi.12921 9196:Bipolar Disorders 9117:(Suppl 1): S214. 8349:978-0-13-219788-5 8001:10.2147/ndt.s5742 7947:(9799): 1306–15. 7801:Otsuka in the U.S 7315:. Crown. p. 7280:10.1159/000135641 7232:Owens DC (2008). 6428:978-0-19-920631-5 6139:978-1-60913-971-1 5982: 5981: 5354:Regulatory status 5260: 5259: 5138:Clopixol Acuphase 4955:Trilafon Dekanoat 4594:Impromen Decanoas 4441: 4440: 3750: 3749: 3670: 3669: 2510:receptor and 5-HT 2237: 2236: 1351:suicidal ideation 1262:Metabolic Effects 1022: 1021: 606:Generic Drug Name 581:black box warning 297:negative symptoms 174:dopamine pathways 88:), also known as 78: 77: 20113: 20070: 20061: 20055:releasing agents 20048: 20039: 20030: 20021: 20009: 19634:Serotonin (5-HT) 19569: 19568: 19202:Serotonin (5-HT) 19149: 19148: 19047:Serotonin (5-HT) 19019: 19018: 18926:Serotonin (5-HT) 18841: 18840: 18677:Hydroxybupropion 18518:Serotonin (5-HT) 18479:trichloroethanol 18457: 18456: 18445: 18444: 17950:Serotonin (5-HT) 17628: 17627: 17269:Serotonin (5-HT) 17151:levofenfluramine 17135:chlorphentermine 17121:4-Methylaminorex 17111: 17110: 17024:prochlorperazine 16848:Phenoxybenzamine 16818:MIN-117 (WF-516) 16473:Serotonin (5-HT) 16089: 16088: 16077: 16076: 16002:Serotonin (5-HT) 15951: 15950: 15865:Serotonin (5-HT) 15840: 15839: 15611:Serotonin (5-HT) 15526: 15525: 15312:Serotonin (5-HT) 15227: 15226: 15109:MIN-117 (WF-516) 14878:Serotonin (5-HT) 14523: 14522: 14511: 14510: 14485: 14478: 14471: 14462: 14461: 14445: 14436: 14427: 14418: 14409: 14400: 14388: 14267:Levofenfluramine 14135:Thiethylperazine 13812:+tranylcypromine 13743:Prochlorperazine 13558:Chlorproethazine 13203: 13195: 13190:-DOPA (levodopa) 13187: 13009: 13008: 12843:+tranylcypromine 12650: 12642: 12632:-DOPA (levodopa) 12629: 12457: 12456: 12430: 12423: 12416: 12407: 12406: 12169:benzisothiazoles 11929:Prochlorperazine 11689: 11682: 11675: 11666: 11665: 11656: 11641: 11639: 11637: 11612: 11591: 11589: 11587: 11582:on July 22, 2018 11581: 11575:. Archived from 11550: 11531: 11530: 11528: 11526: 11511: 11505: 11504: 11502: 11500: 11486: 11480: 11479: 11477: 11475: 11466:. Archived from 11456: 11450: 11448: 11446: 11444: 11435:. Archived from 11425: 11416: 11415: 11413: 11411: 11406:on July 16, 2017 11402:. Archived from 11392: 11386: 11385: 11383: 11381: 11376:. April 25, 2012 11366: 11360: 11359: 11341: 11317: 11311: 11310: 11300: 11276: 11270: 11269: 11233: 11227: 11226: 11216: 11187:Farah A (2005). 11184: 11178: 11177: 11165: 11159: 11158: 11130: 11124: 11123: 11095: 11089: 11088: 11067: 11061: 11060: 11052: 11046: 11045: 11035: 11003: 10994: 10993: 10984:(5 Pt 2): 50–9. 10973: 10967: 10966: 10958: 10949: 10948: 10920: 10911: 10910: 10898: 10892: 10891: 10863: 10857: 10854: 10848: 10847: 10811: 10805: 10802: 10796: 10795: 10759: 10753: 10752: 10750: 10748: 10734: 10728: 10727: 10725: 10723: 10709: 10703: 10702: 10700: 10698: 10682: 10676: 10673: 10667: 10666: 10664: 10662: 10639: 10633: 10632: 10604: 10598: 10597: 10558: 10552: 10551: 10541: 10517: 10511: 10510: 10474: 10468: 10467: 10439: 10433: 10432: 10430: 10428: 10418: 10410: 10404: 10403: 10383: 10377: 10376: 10374: 10372: 10349: 10343: 10342: 10340: 10338: 10315: 10309: 10308: 10306: 10304: 10295:. Archived from 10288: 10282: 10281: 10244: 10238: 10237: 10235: 10233: 10224: 10216: 10207: 10206: 10170: 10164: 10163: 10135: 10129: 10128: 10126: 10124: 10101: 10095: 10094: 10092: 10090: 10076: 10070: 10069: 10067: 10065: 10051: 10045: 10044: 10042: 10040: 10035:. August 8, 2007 10025: 10019: 10018: 10016: 10014: 9995: 9989: 9988: 9986: 9984: 9969: 9963: 9962: 9960: 9958: 9949:. Archived from 9939: 9933: 9932: 9930: 9928: 9905: 9899: 9898: 9896: 9894: 9883:"norepinephrine" 9879: 9873: 9872: 9844: 9838: 9837: 9801: 9795: 9794: 9792: 9790: 9767: 9761: 9760: 9758: 9751: 9740: 9723: 9722: 9702: 9696: 9695: 9675: 9669: 9668: 9632: 9626: 9625: 9605: 9590: 9589: 9568: 9562: 9561: 9559: 9557: 9552:. August 2, 2004 9542: 9536: 9535: 9499: 9493: 9492: 9456: 9441: 9440: 9430: 9398: 9389: 9388: 9386: 9384: 9374: 9367: 9242: 9241: 9231: 9221: 9211: 9187: 9181: 9180: 9143: 9137: 9136: 9134: 9102: 9096: 9095: 9085: 9075: 9051: 9045: 9044: 9026: 9008: 8984: 8978: 8977: 8951: 8927: 8921: 8920: 8883: 8877: 8876: 8868: 8862: 8861: 8851: 8828: 8817: 8816: 8780: 8771: 8770: 8760: 8736: 8717: 8716: 8706: 8666: 8660: 8659: 8615: 8609: 8608: 8598: 8580: 8556: 8550: 8549: 8531: 8507: 8501: 8500: 8490: 8458: 8452: 8451: 8441: 8417: 8411: 8410: 8400: 8368: 8362: 8361: 8333: 8306: 8305: 8295: 8272:World Psychiatry 8263: 8257: 8256: 8246: 8214: 8199: 8198: 8196: 8194: 8189:. Wolters Kluwer 8178: 8172: 8171: 8135: 8129: 8128: 8118: 8108: 8084: 8078: 8077: 8041: 8024: 8023: 8013: 8003: 7979: 7973: 7972: 7935: 7929: 7928: 7918: 7894: 7885: 7884: 7874: 7850: 7837: 7836: 7834: 7832: 7818: 7812: 7811: 7809: 7807: 7793: 7787: 7786: 7750: 7741: 7740: 7703: 7697: 7694: 7685: 7684: 7674: 7664: 7640: 7634: 7633: 7623: 7591: 7585: 7584: 7582: 7580: 7565: 7559: 7558: 7548: 7524: 7518: 7517: 7507: 7497: 7473: 7464: 7463: 7446:(12): CD008121. 7439: 7430: 7429: 7427: 7425: 7409: 7403: 7402: 7400: 7398: 7382: 7376: 7375: 7367: 7356: 7355: 7353: 7351: 7337: 7331: 7330: 7306: 7300: 7299: 7262: 7256: 7255: 7253: 7229: 7223: 7222: 7194: 7188: 7187: 7151: 7145: 7144: 7115: 7109: 7108: 7098: 7074: 7068: 7067: 7057: 7040:(7273): 1371–6. 7025: 7019: 7018: 7008: 6997:10.1002/pds.2082 6976: 6970: 6969: 6959: 6920:Crespo-Facorro B 6915: 6909: 6908: 6898: 6873:(6): 1227–1236. 6858: 6852: 6851: 6841: 6817: 6811: 6810: 6790: 6784: 6783: 6763: 6757: 6756: 6746: 6714: 6708: 6707: 6682:(9690): 635–45. 6671: 6665: 6664: 6654: 6630: 6624: 6623: 6613: 6581: 6575: 6574: 6540: 6531: 6525: 6524: 6522: 6520: 6510: 6502: 6496: 6495: 6489: 6481: 6471: 6439: 6433: 6432: 6414: 6408: 6407: 6397: 6373: 6367: 6366: 6364: 6362: 6348: 6342: 6341: 6305: 6299: 6298: 6288: 6257: 6251: 6250: 6225:(9896): 951–62. 6213: 6202: 6201: 6165: 6152: 6151: 6125: 6119: 6118: 6090: 6062: 6059: 6046: 6043: 6032: 6029: 6008: 6005: 5999: 5995: 5423: 5413: 5403: 5393: 5383: 5373: 5363: 5358: 5357: 5217:Microcrystalline 5103:Risperdal Consta 4937:25–139 days 4850:Zyprexa Relprevv 4816:Haldol Decanoate 4727:14–100 days 4559:Abilify Maintena 4473: 4471: 4464: 4457: 4450: 4442: 4265:1.5 (IR), 6 (XR) 3766: 3761: 3760: 3753:Pharmacokinetics 3738:Partial Agonist 3677: 3676: 2569: 2568: 2420:Some effects of 2262:Pharmacodynamics 2227: 2222: 2217: 2209: 2204: 2199: 2181: 2176: 2168: 2163: 2158: 2153: 2135: 2130: 2122: 2114: 2109: 2071: 2066: 2061: 2056: 2051: 2046: 2041: 2027:aplastic anaemia 2016: 1999: 1976: 1971: 1966: 1961: 1953: 1948: 1943: 1915: 1910: 1905: 1900: 1861: 1856: 1851: 1846: 1841: 1833: 1811: 1806: 1801: 1796: 1791: 1786: 1781: 1776: 1748: 1743: 1739: 1734: 1730: 1722: 1717: 1712: 1693: 1688: 1680: 1672: 1644: 1639: 1634: 1626: 1621: 1616: 1590:thrombocytopenia 1569: 1564: 1559: 1554: 1549: 1544: 1539: 1534: 1520: 1515: 1507: 1502: 1497: 1489: 1468: 1463: 1458: 1453: 1448: 1443: 1438: 1389: 1384: 1379: 1374: 1369: 1364: 1340: 1329: 1324: 1319: 1314: 1250: 1245: 1244: 1060:Drug-induced OCD 601: 596: 595: 415:Bipolar disorder 268:anxiety disorder 262:associated with 256:bipolar disorder 184:—to cause 155:bipolar disorder 45:Skeletal formula 42: 21: 20: 20121: 20120: 20116: 20115: 20114: 20112: 20111: 20110: 20086: 20085: 20084: 20079: 19993: 19958: 19936:chlorprothixene 19670: 19564: 19551: 19508: 19274: 19144: 19131: 19066: 19014: 19001: 18950: 18836: 18823: 18797: 18765:Volatiles/gases 18577: 18567:trichloroethane 18551:Volatiles/gases 18490:Phenylbiguanide 18452: 18441: 18434: 18417: 18387: 18020: 17890:Phenethylamines 17623: 17610: 17589: 17327: 17155:norfenfluramine 17143:dexfenfluramine 17106: 17093: 17068: 17048:trifluoperazine 16699:Chlorprothixene 16533: 16441:Phenethylamines 16252:Bromo-DragonFLY 16084: 16072: 16055: 16034: 15946: 15933: 15905: 15889: 15835: 15822: 15788: 15692: 15521: 15508: 15479: 15374: 15222: 15209: 15178: 14964: 14548:Antidepressants 14518: 14506: 14497: 14489: 14459: 14454: 14376: 14152:Antidepressants 13818:Triflupromazine 13808:Trifluoperazine 13788:Thioproperazine 13568:Chlorprothixene 13502: 13163:Phenethylamines 13003: 12990: 12839:Trifluoperazine 12789:Chlorprothixene 12763: 12733: 12600:Phenethylamines 12451: 12442: 12434: 12404: 12399: 12398: 12383:Clinical trials 12362: 12355:Others/unknown: 12320: 12150: 12027: 11977:Chlorprothixene 11964:Triflupromazine 11959:Trifluoperazine 11949:Thioproperazine 11703: 11693: 11649: 11644: 11635: 11633: 11620: 11585: 11583: 11579: 11548: 11539: 11537:Further reading 11534: 11524: 11522: 11513: 11512: 11508: 11498: 11496: 11488: 11487: 11483: 11473: 11471: 11458: 11457: 11453: 11442: 11440: 11439:on May 26, 2012 11427: 11426: 11419: 11409: 11407: 11394: 11393: 11389: 11379: 11377: 11368: 11367: 11363: 11318: 11314: 11291:(10): 1079–87. 11277: 11273: 11234: 11230: 11185: 11181: 11166: 11162: 11131: 11127: 11096: 11092: 11079:(11): 1689–98. 11068: 11064: 11053: 11049: 11004: 10997: 10974: 10970: 10959: 10952: 10921: 10914: 10899: 10895: 10864: 10860: 10855: 10851: 10812: 10808: 10803: 10799: 10760: 10756: 10746: 10744: 10736: 10735: 10731: 10721: 10719: 10711: 10710: 10706: 10696: 10694: 10684: 10683: 10679: 10675:Culpepper, 2007 10674: 10670: 10660: 10658: 10640: 10636: 10605: 10601: 10559: 10555: 10532:(12): 1339–47. 10518: 10514: 10475: 10471: 10440: 10436: 10426: 10424: 10423:. July 19, 2000 10416: 10412: 10411: 10407: 10400: 10384: 10380: 10370: 10368: 10366: 10350: 10346: 10336: 10334: 10332: 10316: 10312: 10302: 10300: 10291: 10289: 10285: 10245: 10241: 10231: 10229: 10222: 10218: 10217: 10210: 10171: 10167: 10136: 10132: 10122: 10120: 10118: 10102: 10098: 10088: 10086: 10078: 10077: 10073: 10063: 10061: 10053: 10052: 10048: 10038: 10036: 10027: 10026: 10022: 10012: 10010: 9997: 9996: 9992: 9982: 9980: 9971: 9970: 9966: 9956: 9954: 9941: 9940: 9936: 9926: 9924: 9922: 9906: 9902: 9892: 9890: 9887:Cardiosmart.org 9881: 9880: 9876: 9855:(1–3): 125–39. 9845: 9841: 9802: 9798: 9788: 9786: 9784: 9768: 9764: 9756: 9749: 9741: 9726: 9719: 9703: 9699: 9692: 9676: 9672: 9633: 9629: 9622: 9606: 9593: 9583: 9569: 9565: 9555: 9553: 9544: 9543: 9539: 9500: 9496: 9457: 9444: 9399: 9392: 9382: 9380: 9369: 9368: 9245: 9188: 9184: 9144: 9140: 9103: 9099: 9052: 9048: 8985: 8981: 8928: 8924: 8884: 8880: 8869: 8865: 8830: 8829: 8820: 8781: 8774: 8737: 8720: 8667: 8663: 8616: 8612: 8557: 8553: 8508: 8504: 8459: 8455: 8418: 8414: 8369: 8365: 8350: 8334: 8309: 8264: 8260: 8215: 8202: 8192: 8190: 8179: 8175: 8136: 8132: 8085: 8081: 8042: 8027: 7980: 7976: 7936: 7932: 7895: 7888: 7851: 7840: 7830: 7828: 7820: 7819: 7815: 7805: 7803: 7795: 7794: 7790: 7751: 7744: 7704: 7700: 7695: 7688: 7641: 7637: 7592: 7588: 7578: 7576: 7566: 7562: 7525: 7521: 7488:(3): e1001403. 7474: 7467: 7440: 7433: 7423: 7421: 7410: 7406: 7396: 7394: 7383: 7379: 7368: 7359: 7349: 7347: 7339: 7338: 7334: 7327: 7307: 7303: 7263: 7259: 7230: 7226: 7195: 7191: 7152: 7148: 7116: 7112: 7089:(12): 1209–23. 7075: 7071: 7026: 7022: 6977: 6973: 6916: 6912: 6859: 6855: 6818: 6814: 6791: 6787: 6764: 6760: 6715: 6711: 6672: 6668: 6631: 6627: 6582: 6578: 6538: 6532: 6528: 6518: 6516: 6508: 6504: 6503: 6499: 6483: 6482: 6440: 6436: 6429: 6415: 6411: 6388:(12): 1359–69. 6374: 6370: 6360: 6358: 6350: 6349: 6345: 6306: 6302: 6259: 6258: 6254: 6214: 6205: 6176:(9657): 31–41. 6166: 6155: 6140: 6126: 6122: 6091: 6087: 6083: 6071: 6066: 6065: 6060: 6049: 6044: 6035: 6030: 6023: 6014: 6012: 6011: 6006: 6002: 5996: 5992: 5987: 5797:Investigational 5424: 5421: 5414: 5411: 5404: 5401: 5394: 5391: 5384: 5381: 5374: 5371: 5361: 5356: 5340: 5273:agranulocytosis 5265: 5221:nanocrystalline 5194:11–21 days 5066:Piportil Medium 5051:14–21 days 5029:Piportil Longum 4934:13–33 days 4920:Invega Sustenna 4835:18–21 days 4616:21–25 days 4579:30–47 days 4544:54–57 days 4538:24–35 days 4507: 4500: 4494: 4469: 4468: 4435: 4431: 4429: 4427: 4425: 4423: 4301:3 (EM), 17 (PM) 3809: 3800:Bioavailability 3791:Protein binding 3787: 3780: 3764: 3755: 2699: 2691: 2683: 2675: 2667: 2659: 2651: 2643: 2635: 2627: 2619: 2611: 2603: 2595: 2587: 2579: 2559: 2557:Binding profile 2540: 2532: 2528: 2513: 2509: 2505: 2500: 2493: 2487: 2483: 2478: 2472: 2451: 2444: 2430: 2425: 2416: 2404: 2400: 2395: 2391: 2387: 2382: 2377: 2373: 2369: 2365: 2361: 2351: 2331: 2323: 2319: 2315: 2303: 2299: 2295: 2291: 2287: 2283: 2277: 2264: 2259: 2242: 2240:Discontinuation 2225: 2220: 2215: 2207: 2202: 2197: 2179: 2174: 2166: 2161: 2156: 2151: 2133: 2128: 2120: 2112: 2107: 2097:, galactorrhea 2069: 2064: 2059: 2054: 2049: 2044: 2039: 2014: 1997: 1974: 1969: 1964: 1959: 1951: 1946: 1941: 1913: 1908: 1903: 1898: 1859: 1854: 1849: 1844: 1839: 1831: 1809: 1804: 1799: 1794: 1789: 1784: 1779: 1774: 1755:Agranulocytosis 1746: 1741: 1737: 1732: 1728: 1720: 1715: 1710: 1691: 1686: 1678: 1670: 1642: 1637: 1632: 1624: 1619: 1614: 1567: 1562: 1557: 1552: 1547: 1542: 1537: 1532: 1518: 1513: 1505: 1500: 1495: 1487: 1466: 1461: 1456: 1451: 1446: 1441: 1436: 1412:agranulocytosis 1387: 1382: 1377: 1372: 1367: 1362: 1338: 1327: 1322: 1317: 1312: 1273: 1248: 1243: 1183: 1175: 1167: 1158: 1153: 1145: 1137: 1130: 1102: 1083: 1068: 1062: 1027: 1025:Adverse effects 1007:- Inefficacious 599: 594: 573: 557: 453: 417: 329: 292: 248: 52: 17: 12: 11: 5: 20119: 20109: 20108: 20103: 20098: 20081: 20080: 20078: 20077: 20068: 20059: 20046: 20037: 20028: 20019: 20006: 20003: 20002: 19999: 19998: 19995: 19994: 19992: 19991: 19981: 19963: 19960: 19959: 19957: 19956: 19951: 19932:chlorpromazine 19928:acetophenazine 19921: 19903: 19881: 19876: 19871: 19866: 19861: 19856: 19851: 19846: 19841: 19836: 19831: 19826: 19821: 19816: 19811: 19806: 19752: 19747: 19742: 19737: 19675: 19672: 19671: 19669: 19668: 19646: 19636: 19631: 19626: 19621: 19616: 19611: 19606: 19596: 19591: 19586: 19581: 19572: 19566: 19562: 19557: 19556: 19553: 19552: 19550: 19549: 19539: 19513: 19510: 19509: 19507: 19506: 19499:chlorpromazine 19492: 19470: 19456: 19451: 19446: 19441: 19436: 19431: 19426: 19421: 19416: 19411: 19406: 19401: 19396: 19391: 19386: 19381: 19376: 19371: 19366: 19361: 19356: 19351: 19346: 19341: 19336: 19331: 19326: 19288: 19279: 19276: 19275: 19273: 19272: 19267: 19262: 19204: 19199: 19194: 19152: 19146: 19142: 19137: 19136: 19133: 19132: 19130: 19129: 19119: 19101: 19100: 19095: 19090: 19085: 19080: 19071: 19068: 19067: 19065: 19064: 19062:Valerenic acid 19059: 19049: 19044: 19022: 19016: 19012: 19007: 19006: 19003: 19002: 19000: 18999: 18994: 18989: 18984: 18979: 18974: 18969: 18964: 18955: 18952: 18951: 18949: 18948: 18943: 18938: 18933: 18928: 18923: 18918: 18913: 18908: 18903: 18898: 18893: 18888: 18886:Metoclopramide 18883: 18878: 18873: 18868: 18863: 18858: 18853: 18844: 18838: 18834: 18829: 18828: 18825: 18824: 18822: 18821: 18811: 18802: 18799: 18798: 18796: 18795: 18790: 18785: 18780: 18762: 18752: 18747: 18742: 18737: 18719: 18714: 18709: 18704: 18699: 18694: 18689: 18684: 18679: 18674: 18669: 18664: 18659: 18654: 18649: 18644: 18639: 18634: 18629: 18624: 18606: 18601: 18596: 18591: 18582: 18579: 18578: 18576: 18575: 18570: 18548: 18530: 18525: 18520: 18515: 18510: 18492: 18487: 18482: 18460: 18454: 18450: 18442: 18436: 18432: 18427: 18426: 18423: 18422: 18419: 18418: 18416: 18415: 18401: 18392: 18389: 18388: 18386: 18385: 18380: 18361:chlorpromazine 18354: 18340: 18335: 18330: 18325: 18295: 18290: 18285: 18280: 18275: 18270: 18265: 18260: 18255: 18250: 18245: 18240: 18235: 18230: 18225: 18220: 18215: 18210: 18205: 18200: 18195: 18190: 18185: 18180: 18175: 18137: 18132: 18127: 18122: 18117: 18115:Cyproheptadine 18112: 18107: 18102: 18097: 18039: 18034: 18025: 18022: 18021: 18019: 18018: 18013: 18008: 18003: 17998: 17952: 17947: 17942: 17937: 17932: 17927: 17901: 17887: 17882: 17877: 17872: 17867: 17862: 17840: 17835: 17830: 17772: 17750: 17745: 17740: 17735: 17730: 17725: 17691: 17665: 17631: 17625: 17621: 17616: 17615: 17612: 17611: 17609: 17608: 17594: 17591: 17590: 17588: 17587: 17582: 17577: 17574:chlorpromazine 17567: 17562: 17544: 17539: 17534: 17529: 17524: 17519: 17514: 17509: 17504: 17499: 17494: 17489: 17484: 17479: 17474: 17469: 17464: 17459: 17454: 17449: 17444: 17439: 17409: 17404: 17402:Cyproheptadine 17399: 17341: 17332: 17329: 17328: 17326: 17325: 17271: 17266: 17261: 17256: 17246: 17224: 17219: 17185: 17163: 17158: 17128: 17123: 17114: 17108: 17104: 17099: 17098: 17095: 17094: 17092: 17091: 17073: 17070: 17069: 17067: 17066: 17061: 17056: 17051: 16996:chlorpromazine 16989: 16979: 16949: 16944: 16939: 16934: 16929: 16895: 16890: 16885: 16880: 16875: 16870: 16865: 16860: 16855: 16850: 16845: 16840: 16835: 16830: 16825: 16820: 16815: 16810: 16805: 16800: 16795: 16790: 16785: 16780: 16775: 16770: 16765: 16760: 16726: 16721: 16716: 16711: 16706: 16701: 16696: 16594: 16589: 16574:cyproheptadine 16570:Antihistamines 16567: 16562: 16557: 16552: 16547: 16538: 16535: 16534: 16532: 16531: 16485: 16480: 16475: 16470: 16452: 16438: 16436:SCHEMBL5334361 16433: 16428: 16423: 16418: 16413: 16408: 16403: 16381: 16376: 16371: 16366: 16361: 16291: 16286: 16264: 16259: 16254: 16249: 16244: 16239: 16205: 16179: 16174: 16169: 16139: 16092: 16086: 16082: 16074: 16070: 16065: 16064: 16061: 16060: 16057: 16056: 16054: 16053: 16048: 16039: 16036: 16035: 16033: 16032: 16022: 16004: 15999: 15994: 15989: 15968: 15963: 15954: 15948: 15944: 15939: 15938: 15935: 15934: 15932: 15931: 15910: 15907: 15906: 15904: 15903: 15894: 15891: 15890: 15888: 15887: 15877: 15867: 15862: 15852: 15843: 15837: 15833: 15828: 15827: 15824: 15823: 15821: 15820: 15802: 15793: 15790: 15789: 15787: 15786: 15781: 15776: 15771: 15766: 15761: 15756: 15751: 15746: 15741: 15736: 15731: 15726: 15716: 15711: 15706: 15697: 15694: 15693: 15691: 15690: 15660: 15618: 15613: 15608: 15603: 15598: 15593: 15588: 15583: 15578: 15548: 15543: 15538: 15529: 15523: 15519: 15514: 15513: 15510: 15509: 15507: 15506: 15484: 15481: 15480: 15478: 15477: 15472: 15467: 15462: 15457: 15452: 15447: 15442: 15437: 15427: 15422: 15388: 15379: 15376: 15375: 15373: 15372: 15367: 15345: 15340: 15314: 15309: 15304: 15299: 15269: 15264: 15259: 15254: 15249: 15244: 15239: 15230: 15224: 15220: 15215: 15214: 15211: 15210: 15208: 15207: 15197: 15192: 15183: 15180: 15179: 15177: 15176: 15171: 15166: 15161: 15156: 15151: 15146: 15141: 15136: 15131: 15126: 15121: 15116: 15111: 15106: 15101: 15096: 15091: 15086: 15081: 15076: 15071: 15061: 15056: 15051: 15046: 14996: 14991: 14969: 14966: 14965: 14963: 14962: 14957: 14952: 14947: 14942: 14937: 14932: 14890: 14885: 14880: 14875: 14870: 14865: 14860: 14855: 14850: 14845: 14840: 14835: 14830: 14825: 14820: 14815: 14810: 14805: 14800: 14795: 14790: 14785: 14780: 14775: 14770: 14765: 14760: 14755: 14750: 14745: 14740: 14735: 14730: 14688: 14683: 14678: 14673: 14668: 14663: 14658: 14653: 14648: 14643: 14617: 14579: 14545: 14540: 14535: 14526: 14520: 14516: 14508: 14504: 14499: 14498: 14488: 14487: 14480: 14473: 14465: 14456: 14455: 14453: 14452: 14443: 14434: 14425: 14416: 14407: 14398: 14385: 14382: 14381: 14378: 14377: 14375: 14374: 14369: 14364: 14359: 14354: 14349: 14344: 14339: 14334: 14329: 14324: 14319: 14314: 14309: 14304: 14299: 14294: 14289: 14284: 14279: 14274: 14269: 14264: 14259: 14254: 14252:Isocorypalmine 14249: 14244: 14239: 14234: 14229: 14224: 14219: 14214: 14209: 14204: 14199: 14194: 14189: 14179: 14178: 14173: 14168: 14163: 14158: 14148: 14147: 14142: 14137: 14132: 14127: 14122: 14120:Metoclopramide 14117: 14112: 14107: 14102: 14097: 14095:Deudomperidone 14092: 14087: 14082: 14077: 14072: 14067: 14062: 14060:Aceprometazine 14052: 14051: 14046: 14041: 14036: 14031: 14026: 14021: 14016: 14011: 14006: 14001: 13996: 13991: 13986: 13984:Piperacetazine 13981: 13976: 13971: 13961: 13956: 13951: 13946: 13941: 13936: 13931: 13926: 13921: 13916: 13911: 13906: 13901: 13896: 13891: 13886: 13881: 13876: 13871: 13866: 13861: 13856: 13851: 13846: 13836: 13835: 13833:Zuclopenthixol 13830: 13825: 13820: 13815: 13805: 13800: 13795: 13790: 13785: 13780: 13775: 13770: 13765: 13760: 13755: 13750: 13745: 13740: 13735: 13730: 13725: 13720: 13717:+amitriptyline 13710: 13705: 13700: 13695: 13690: 13685: 13680: 13675: 13670: 13665: 13660: 13655: 13650: 13645: 13640: 13635: 13630: 13625: 13615: 13610: 13605: 13600: 13595: 13590: 13585: 13580: 13575: 13570: 13565: 13563:Chlorpromazine 13560: 13555: 13550: 13545: 13540: 13535: 13530: 13525: 13523:Acetophenazine 13520: 13510: 13508: 13504: 13503: 13501: 13500: 13495: 13490: 13485: 13480: 13475: 13470: 13465: 13460: 13455: 13450: 13445: 13440: 13435: 13430: 13425: 13420: 13415: 13410: 13405: 13400: 13395: 13390: 13385: 13380: 13375: 13370: 13365: 13360: 13355: 13350: 13345: 13340: 13335: 13330: 13325: 13320: 13315: 13310: 13305: 13300: 13295: 13290: 13280: 13279: 13274: 13269: 13264: 13259: 13254: 13249: 13244: 13239: 13229: 13219: 13218: 13213: 13208: 13200: 13198:-Phenylalanine 13192: 13184: 13179: 13174: 13169: 13159: 13158: 13153: 13148: 13143: 13138: 13128: 13127: 13122: 13117: 13112: 13107: 13102: 13097: 13092: 13087: 13082: 13077: 13067: 13066: 13061: 13056: 13051: 13046: 13040:Aminotetralins 13036: 13035: 13030: 13025: 13015: 13013: 13006: 13001: 12996: 12995: 12992: 12991: 12989: 12988: 12983: 12978: 12973: 12968: 12963: 12958: 12948: 12947: 12942: 12937: 12932: 12927: 12922: 12917: 12912: 12902: 12897: 12892: 12887: 12882: 12877: 12872: 12867: 12862: 12852: 12851: 12849:Zuclopenthixol 12846: 12836: 12831: 12826: 12821: 12818:+amitriptyline 12811: 12806: 12801: 12791: 12786: 12784:Chlorpromazine 12781: 12771: 12769: 12765: 12764: 12762: 12761: 12756: 12751: 12741: 12739: 12735: 12734: 12732: 12731: 12726: 12721: 12716: 12711: 12706: 12701: 12696: 12691: 12686: 12681: 12679:Isocorypalmine 12676: 12671: 12661: 12660: 12655: 12647: 12645:-Phenylalanine 12639: 12634: 12626: 12621: 12616: 12611: 12606: 12596: 12595: 12590: 12585: 12580: 12575: 12570: 12565: 12555: 12554: 12549: 12544: 12539: 12534: 12529: 12524: 12514: 12513: 12508: 12503: 12498: 12493: 12488: 12483: 12478: 12473: 12463: 12461: 12454: 12449: 12444: 12443: 12433: 12432: 12425: 12418: 12410: 12401: 12400: 12397: 12396: 12395: 12394: 12391: 12380: 12374: 12368: 12367: 12364: 12363: 12361: 12360: 12351: 12350: 12345: 12340: 12328: 12326: 12322: 12321: 12319: 12318: 12313: 12308: 12299: 12298: 12293: 12288: 12278: 12273: 12261: 12260: 12255: 12250: 12245: 12244: 12243: 12222: 12221: 12214:Butyrophenones 12209: 12208: 12203: 12198: 12193: 12192: 12191: 12181: 12176: 12160: 12158: 12152: 12151: 12149: 12148: 12139: 12138: 12133: 12128: 12123: 12118: 12113: 12108: 12096: 12095: 12088:Butyrophenones 12083: 12082: 12077: 12072: 12067: 12062: 12057: 12052: 12047: 12035: 12033: 12029: 12028: 12026: 12025: 12024: 12023: 12018: 12011:Zuclopenthixol 12008: 12003: 12002: 12001: 11991: 11990: 11989: 11979: 11967: 11966: 11961: 11956: 11951: 11946: 11941: 11936: 11931: 11926: 11925: 11924: 11919: 11909: 11907:Piperacetazine 11904: 11903: 11902: 11897: 11892: 11882: 11877: 11872: 11867: 11862: 11861: 11860: 11855: 11845: 11840: 11835: 11833:Chlorpromazine 11830: 11825: 11820: 11818:Acetophenazine 11815: 11808:Phenothiazines 11803: 11802: 11797: 11792: 11780: 11779: 11774: 11769: 11764: 11759: 11754: 11753: 11752: 11742: 11737: 11736: 11735: 11725: 11718:Butyrophenones 11713: 11711: 11705: 11704: 11696:Antipsychotics 11692: 11691: 11684: 11677: 11669: 11663: 11662: 11648: 11647:External links 11645: 11643: 11642: 11618: 11613: 11592: 11540: 11538: 11535: 11533: 11532: 11506: 11481: 11451: 11417: 11387: 11361: 11312: 11271: 11228: 11179: 11160: 11125: 11090: 11062: 11047: 10995: 10968: 10950: 10912: 10893: 10858: 10849: 10806: 10797: 10754: 10729: 10704: 10677: 10668: 10634: 10599: 10553: 10512: 10469: 10434: 10405: 10398: 10378: 10364: 10344: 10331:978-1437716795 10330: 10310: 10283: 10239: 10208: 10165: 10130: 10116: 10096: 10071: 10046: 10020: 9990: 9964: 9934: 9920: 9900: 9874: 9839: 9796: 9782: 9762: 9724: 9717: 9697: 9690: 9670: 9627: 9620: 9591: 9581: 9563: 9537: 9494: 9442: 9390: 9243: 9202:(5): 440–460. 9182: 9138: 9111:Schizophr Bull 9097: 9046: 8979: 8942:(8): 737–748. 8922: 8895:(1–3): 162–9. 8878: 8863: 8818: 8772: 8718: 8661: 8626:(5): 385–387. 8610: 8571:(5): 649–650. 8551: 8522:(3): 375–377. 8502: 8453: 8412: 8363: 8348: 8307: 8258: 8200: 8173: 8130: 8093:BMC Psychiatry 8079: 8025: 7974: 7930: 7886: 7838: 7813: 7788: 7742: 7698: 7686: 7649:BMC Psychiatry 7635: 7606:(12): 1251–8. 7586: 7560: 7519: 7465: 7431: 7404: 7377: 7357: 7345:www.mdedge.com 7332: 7326:978-0307452412 7325: 7301: 7257: 7224: 7189: 7146: 7110: 7069: 7020: 6971: 6934:(4): 217–229. 6910: 6853: 6832:(5): 385–392. 6812: 6785: 6774:(12): 1821–9. 6758: 6709: 6666: 6645:(5): 361–365. 6625: 6576: 6526: 6497: 6434: 6427: 6409: 6368: 6343: 6300: 6252: 6203: 6153: 6138: 6120: 6084: 6082: 6079: 6078: 6077: 6070: 6067: 6064: 6063: 6047: 6033: 6020: 6019: 6010: 6009: 6000: 5989: 5988: 5986: 5983: 5980: 5979: 5976: 5973: 5970: 5967: 5964: 5961: 5955: 5954: 5951: 5948: 5947:(some members) 5945: 5942: 5939: 5936: 5930: 5929: 5926: 5923: 5920: 5917: 5914: 5911: 5905: 5904: 5901: 5898: 5895: 5892: 5889: 5886: 5880: 5879: 5876: 5873: 5870: 5867: 5864: 5861: 5855: 5854: 5851: 5848: 5845: 5842: 5839: 5836: 5830: 5829: 5826: 5823: 5820: 5817: 5814: 5811: 5805: 5804: 5801: 5798: 5795: 5792: 5789: 5786: 5780: 5779: 5776: 5773: 5770: 5767: 5764: 5761: 5755: 5754: 5751: 5748: 5745: 5742: 5739: 5736: 5730: 5729: 5726: 5723: 5720: 5717: 5714: 5711: 5705: 5704: 5701: 5698: 5695: 5692: 5689: 5686: 5680: 5679: 5676: 5673: 5670: 5667: 5664: 5661: 5655: 5654: 5651: 5648: 5645: 5642: 5639: 5636: 5630: 5629: 5626: 5623: 5620: 5617: 5614: 5611: 5605: 5604: 5601: 5598: 5595: 5592: 5589: 5586: 5580: 5579: 5576: 5573: 5570: 5567: 5564: 5561: 5555: 5554: 5551: 5548: 5545: 5542: 5539: 5536: 5530: 5529: 5526: 5523: 5520: 5517: 5514: 5511: 5505: 5504: 5501: 5498: 5495: 5492: 5489: 5486: 5480: 5479: 5476: 5473: 5470: 5467: 5464: 5461: 5455: 5454: 5451: 5448: 5447:(some members) 5445: 5442: 5439: 5436: 5430: 5429: 5422:United Kingdom 5419: 5409: 5399: 5389: 5379: 5369: 5365: 5364: 5355: 5352: 5339: 5336: 5317:extrapyramidal 5269:chlorpromazine 5264: 5261: 5258: 5257: 5256:See template. 5233:(specifically 5201: 5200: 5198: 5195: 5192: 5189: 5186: 5183: 5178: 5173: 5172:Clopixol Depot 5170: 5164: 5163: 5161: 5158: 5155: 5152: 5149: 5144: 5139: 5136: 5130: 5129: 5127: 5124: 5121: 5118: 5115: 5112: 5107: 5104: 5101: 5095: 5094: 5092: 5089: 5086: 5083: 5080: 5077: 5072: 5067: 5064: 5058: 5057: 5055: 5052: 5049: 5046: 5045:9–10 days 5043: 5040: 5035: 5030: 5027: 5021: 5020: 5018: 5015: 5012: 5009: 5006: 5003: 4998: 4993: 4990: 4984: 4983: 4981: 4978: 4975: 4972: 4969: 4966: 4961: 4956: 4953: 4947: 4946: 4944: 4941: 4938: 4935: 4932: 4929: 4924: 4921: 4918: 4912: 4911: 4909: 4906: 4903: 4900: 4897: 4894: 4891: 4886: 4883: 4877: 4876: 4874: 4871: 4868: 4865: 4862: 4859: 4854: 4851: 4848: 4842: 4841: 4839: 4836: 4833: 4830: 4827: 4822: 4817: 4814: 4808: 4807: 4805: 4802: 4799: 4796: 4793: 4790: 4785: 4780: 4779:Imap, Redeptin 4777: 4771: 4770: 4768: 4765: 4762: 4759: 4756: 4753: 4748: 4743: 4740: 4734: 4733: 4731: 4728: 4725: 4724:1–10 days 4722: 4719: 4716: 4711: 4706: 4703: 4697: 4696: 4694: 4691: 4688: 4685: 4684:4–10 days 4682: 4679: 4674: 4669: 4666: 4660: 4659: 4657: 4654: 4651: 4648: 4645: 4642: 4637: 4632: 4631:Sordinol Depot 4629: 4623: 4622: 4620: 4617: 4614: 4611: 4608: 4605: 4600: 4595: 4592: 4586: 4585: 4583: 4580: 4577: 4574: 4571: 4568: 4563: 4560: 4557: 4551: 4550: 4548: 4545: 4542: 4539: 4536: 4533: 4528: 4525: 4522: 4516: 4515: 4512: 4509: 4505: 4502: 4498: 4495: 4492: 4489: 4486: 4483: 4480: 4477: 4467: 4466: 4459: 4452: 4444: 4439: 4438: 4433: 4421:Acronyms used: 4416: 4415: 4412: 4409: 4406: 4403: 4400: 4397: 4394: 4391: 4388: 4382: 4381: 4378: 4375: 4372: 4363: 4360: 4357: 4354: 4351: 4348: 4342: 4341: 4338: 4335: 4332: 4327: 4324: 4321: 4318: 4315: 4312: 4306: 4305: 4302: 4299: 4296: 4291: 4288: 4285: 4282: 4279: 4276: 4270: 4269: 4266: 4263: 4260: 4255: 4252: 4249: 4246: 4245:6 (IR), 7 (XR) 4243: 4240: 4234: 4233: 4230: 4227: 4224: 4221: 4218: 4215: 4212: 4209: 4206: 4200: 4199: 4196: 4193: 4190: 4181: 4178: 4175: 4172: 4169: 4166: 4160: 4159: 4156: 4153: 4150: 4141: 4138: 4135: 4132: 4129: 4126: 4120: 4119: 4116: 4113: 4110: 4107: 4104: 4101: 4098: 4095: 4092: 4086: 4085: 4082: 4079: 4076: 4071: 4068: 4065: 4062: 4059: 4056: 4050: 4049: 4046: 4043: 4040: 4031: 4028: 4025: 4022: 4019: 4016: 4010: 4009: 4006: 4003: 4000: 3987: 3984: 3981: 3978: 3975: 3972: 3966: 3965: 3962: 3959: 3956: 3951: 3948: 3945: 3942: 3939: 3936: 3930: 3929: 3926: 3923: 3920: 3911: 3908: 3905: 3902: 3899: 3896: 3890: 3889: 3886: 3883: 3876: 3867: 3864: 3861: 3858: 3855: 3852: 3846: 3845: 3842: 3839: 3836: 3833: 3830: 3827: 3824: 3821: 3818: 3812: 3811: 3807: 3804: 3801: 3798: 3795: 3792: 3789: 3785: 3782: 3778: 3775: 3772: 3768: 3767: 3754: 3751: 3748: 3747: 3744: 3740: 3739: 3736: 3732: 3731: 3728: 3724: 3723: 3720: 3716: 3715: 3712: 3708: 3707: 3704: 3700: 3699: 3696: 3692: 3691: 3688: 3684: 3683: 3680: 3668: 3667: 3664: 3661: 3658: 3655: 3652: 3650: 3647: 3644: 3641: 3638: 3635: 3632: 3629: 3626: 3623: 3620: 3614: 3613: 3610: 3607: 3604: 3601: 3598: 3596: 3593: 3590: 3587: 3584: 3581: 3578: 3575: 3572: 3569: 3566: 3560: 3559: 3556: 3553: 3550: 3547: 3544: 3542: 3539: 3536: 3533: 3530: 3527: 3524: 3521: 3518: 3515: 3512: 3506: 3505: 3502: 3499: 3496: 3493: 3490: 3488: 3485: 3482: 3479: 3476: 3473: 3470: 3467: 3464: 3461: 3458: 3452: 3451: 3448: 3445: 3442: 3439: 3436: 3433: 3430: 3427: 3424: 3421: 3418: 3415: 3412: 3409: 3406: 3403: 3397: 3396: 3393: 3390: 3387: 3384: 3381: 3379: 3376: 3373: 3370: 3367: 3364: 3361: 3358: 3355: 3352: 3349: 3343: 3342: 3339: 3336: 3333: 3330: 3327: 3325: 3322: 3319: 3316: 3313: 3310: 3307: 3304: 3301: 3298: 3295: 3289: 3288: 3285: 3282: 3279: 3276: 3273: 3271: 3268: 3265: 3262: 3259: 3256: 3253: 3250: 3247: 3244: 3241: 3235: 3234: 3231: 3228: 3225: 3222: 3219: 3217: 3214: 3211: 3208: 3205: 3202: 3199: 3196: 3193: 3190: 3187: 3181: 3180: 3177: 3174: 3171: 3168: 3165: 3163: 3160: 3157: 3154: 3151: 3148: 3145: 3142: 3139: 3136: 3133: 3127: 3126: 3123: 3120: 3117: 3114: 3111: 3109: 3106: 3103: 3100: 3097: 3094: 3091: 3088: 3085: 3082: 3079: 3073: 3072: 3069: 3066: 3063: 3060: 3057: 3055: 3052: 3049: 3046: 3043: 3040: 3037: 3034: 3031: 3028: 3025: 3019: 3018: 3015: 3012: 3009: 3007: 3004: 3002: 2999: 2997: 2994: 2991: 2989: 2986: 2984: 2981: 2978: 2976: 2970: 2969: 2966: 2963: 2961: 2959: 2957: 2954: 2951: 2948: 2945: 2942: 2939: 2936: 2933: 2930: 2927: 2924: 2918: 2917: 2914: 2911: 2908: 2905: 2902: 2900: 2897: 2894: 2891: 2888: 2885: 2882: 2879: 2876: 2873: 2870: 2864: 2863: 2860: 2857: 2854: 2851: 2848: 2846: 2843: 2840: 2837: 2834: 2831: 2828: 2825: 2822: 2819: 2816: 2810: 2809: 2806: 2803: 2800: 2797: 2794: 2792: 2789: 2786: 2783: 2780: 2777: 2774: 2771: 2768: 2765: 2762: 2756: 2755: 2752: 2749: 2746: 2743: 2740: 2738: 2735: 2732: 2729: 2726: 2723: 2720: 2717: 2714: 2711: 2708: 2702: 2701: 2697: 2693: 2689: 2685: 2681: 2677: 2673: 2669: 2665: 2661: 2657: 2653: 2649: 2645: 2641: 2637: 2633: 2629: 2625: 2621: 2617: 2613: 2609: 2605: 2601: 2597: 2593: 2589: 2585: 2581: 2577: 2573: 2558: 2555: 2539: 2536: 2530: 2526: 2511: 2507: 2503: 2498: 2491: 2485: 2481: 2476: 2470: 2449: 2442: 2428: 2423: 2414: 2402: 2398: 2393: 2389: 2385: 2380: 2375: 2371: 2367: 2363: 2359: 2349: 2329: 2321: 2317: 2313: 2312:, endogenous D 2301: 2297: 2293: 2289: 2285: 2281: 2275: 2263: 2260: 2258: 2255: 2241: 2238: 2235: 2234: 2231: 2228: 2223: 2218: 2213: 2210: 2205: 2200: 2195: 2189: 2188: 2185: 2182: 2177: 2172: 2169: 2164: 2159: 2154: 2149: 2143: 2142: 2139: 2136: 2131: 2126: 2123: 2118: 2115: 2110: 2105: 2099: 2098: 2075: 2072: 2067: 2062: 2057: 2052: 2047: 2042: 2037: 2031: 2030: 2023: 2020: 2017: 2012: 2009: 2006: 2003: 2000: 1995: 1989: 1988: 1977: 1972: 1967: 1962: 1957: 1954: 1949: 1944: 1939: 1933: 1932: 1922: 1919: 1916: 1911: 1906: 1901: 1896: 1893: 1890: 1884: 1883: 1865: 1862: 1857: 1852: 1847: 1842: 1837: 1834: 1829: 1823: 1822: 1812: 1807: 1802: 1797: 1792: 1787: 1782: 1777: 1772: 1766: 1765: 1752: 1749: 1744: 1735: 1726: 1723: 1718: 1713: 1708: 1702: 1701: 1694: 1689: 1684: 1681: 1676: 1673: 1668: 1665: 1662: 1656: 1655: 1648: 1645: 1640: 1635: 1630: 1627: 1622: 1617: 1612: 1606: 1605: 1570: 1565: 1560: 1555: 1550: 1545: 1540: 1535: 1530: 1524: 1523: 1521: 1516: 1511: 1508: 1503: 1498: 1493: 1490: 1485: 1479: 1478: 1472: 1469: 1464: 1459: 1454: 1449: 1444: 1439: 1434: 1428: 1427: 1404:rhabdomyolysis 1396: 1393: 1390: 1385: 1380: 1375: 1370: 1365: 1360: 1354: 1353: 1344: 1341: 1336: 1333: 1330: 1325: 1320: 1315: 1310: 1304: 1303: 1300: 1294: 1288: 1279: 1276: 1269: 1264: 1259: 1256: 1252: 1251: 1242: 1239: 1181: 1173: 1165: 1156: 1151: 1143: 1135: 1128: 1101: 1098: 1082: 1079: 1064:Main article: 1061: 1058: 1026: 1023: 1020: 1019: 1018: 1017: 1014: 1011: 1008: 997: 996: 993: 990: 987: 984: 981: 975: 974: 971: 968: 965: 962: 959: 953: 952: 949: 946: 943: 940: 937: 931: 930: 927: 924: 921: 918: 915: 909: 908: 905: 902: 899: 896: 893: 887: 886: 883: 880: 877: 874: 871: 865: 864: 861: 858: 855: 852: 849: 843: 842: 839: 836: 833: 830: 827: 821: 820: 817: 814: 811: 808: 805: 799: 798: 795: 792: 789: 786: 783: 777: 776: 773: 770: 767: 764: 761: 755: 754: 751: 748: 745: 742: 739: 733: 732: 729: 726: 723: 720: 717: 711: 710: 707: 704: 701: 698: 695: 689: 688: 685: 682: 679: 676: 673: 667: 666: 663: 660: 657: 654: 651: 645: 644: 641: 638: 635: 632: 629: 623: 622: 619: 616: 613: 610: 607: 603: 602: 593: 590: 572: 569: 556: 553: 495: 494: 489: 484: 479: 474: 469: 452: 449: 425:mixed episodes 416: 413: 328: 325: 291: 288: 247: 244: 186:extrapyramidal 76: 75: 69: 68: 64: 63: 60: 54: 53: 43: 35: 34: 26: 25: 15: 9: 6: 4: 3: 2: 20118: 20107: 20104: 20102: 20099: 20097: 20094: 20093: 20091: 20075: 20074: 20069: 20066: 20065: 20060: 20057: 20056: 20052: 20047: 20044: 20043: 20042:Melatonergics 20038: 20035: 20034: 20033:Dopaminergics 20029: 20026: 20025: 20020: 20017: 20016: 20013: 20008: 20007: 20004: 19989: 19985: 19982: 19979: 19975: 19971: 19968: 19965: 19964: 19961: 19955: 19952: 19949: 19945: 19941: 19937: 19933: 19929: 19925: 19922: 19919: 19915: 19911: 19910:amitriptyline 19907: 19904: 19901: 19897: 19893: 19889: 19885: 19882: 19880: 19877: 19875: 19872: 19870: 19867: 19865: 19862: 19860: 19857: 19855: 19852: 19850: 19847: 19845: 19842: 19840: 19837: 19835: 19832: 19830: 19827: 19825: 19822: 19820: 19817: 19815: 19812: 19810: 19807: 19804: 19800: 19796: 19792: 19788: 19784: 19780: 19776: 19772: 19768: 19767:bromocriptine 19764: 19760: 19756: 19753: 19751: 19748: 19746: 19743: 19741: 19738: 19735: 19731: 19727: 19723: 19719: 19715: 19711: 19707: 19703: 19699: 19698:brexpiprazole 19695: 19691: 19687: 19683: 19680: 19677: 19676: 19673: 19666: 19662: 19658: 19654: 19650: 19647: 19644: 19640: 19637: 19635: 19632: 19630: 19627: 19625: 19622: 19620: 19617: 19615: 19612: 19610: 19607: 19604: 19600: 19597: 19595: 19592: 19590: 19587: 19585: 19582: 19580: 19577: 19574: 19573: 19570: 19567: 19565: 19558: 19547: 19543: 19540: 19537: 19533: 19529: 19528:bromocriptine 19525: 19521: 19518: 19515: 19514: 19511: 19504: 19500: 19496: 19493: 19490: 19489:nortriptyline 19486: 19482: 19478: 19477:amitriptyline 19474: 19471: 19468: 19464: 19460: 19457: 19455: 19452: 19450: 19447: 19445: 19442: 19440: 19437: 19435: 19432: 19430: 19427: 19425: 19422: 19420: 19417: 19415: 19412: 19410: 19407: 19405: 19402: 19400: 19397: 19395: 19392: 19390: 19387: 19385: 19382: 19380: 19377: 19375: 19372: 19370: 19367: 19365: 19362: 19360: 19357: 19355: 19352: 19350: 19347: 19345: 19342: 19340: 19337: 19335: 19332: 19330: 19327: 19324: 19320: 19316: 19312: 19308: 19304: 19300: 19296: 19292: 19289: 19287: 19284: 19281: 19280: 19277: 19271: 19268: 19266: 19263: 19260: 19256: 19252: 19248: 19244: 19240: 19236: 19232: 19228: 19224: 19220: 19216: 19212: 19208: 19205: 19203: 19200: 19198: 19195: 19192: 19188: 19184: 19180: 19176: 19172: 19168: 19164: 19160: 19157: 19154: 19153: 19150: 19147: 19145: 19138: 19127: 19123: 19120: 19117: 19113: 19109: 19106: 19103: 19102: 19099: 19096: 19094: 19091: 19089: 19086: 19084: 19081: 19079: 19076: 19073: 19072: 19069: 19063: 19060: 19057: 19053: 19050: 19048: 19045: 19042: 19038: 19034: 19030: 19027: 19024: 19023: 19020: 19017: 19015: 19008: 18998: 18995: 18993: 18990: 18988: 18985: 18983: 18980: 18978: 18975: 18973: 18970: 18968: 18965: 18963: 18960: 18957: 18956: 18953: 18947: 18944: 18942: 18939: 18937: 18934: 18932: 18929: 18927: 18924: 18922: 18919: 18917: 18914: 18912: 18909: 18907: 18904: 18902: 18899: 18897: 18894: 18892: 18889: 18887: 18884: 18882: 18879: 18877: 18874: 18872: 18869: 18867: 18864: 18862: 18859: 18857: 18854: 18852: 18849: 18846: 18845: 18842: 18839: 18837: 18830: 18819: 18815: 18812: 18810: 18807: 18804: 18803: 18800: 18794: 18791: 18789: 18786: 18784: 18781: 18778: 18774: 18770: 18769:nitrous oxide 18766: 18763: 18760: 18756: 18753: 18751: 18748: 18746: 18743: 18741: 18738: 18735: 18731: 18727: 18723: 18720: 18718: 18717:Tedatioxetine 18715: 18713: 18710: 18708: 18705: 18703: 18700: 18698: 18695: 18693: 18690: 18688: 18685: 18683: 18680: 18678: 18675: 18673: 18670: 18668: 18667:Galanolactone 18665: 18663: 18660: 18658: 18655: 18653: 18650: 18648: 18645: 18643: 18640: 18638: 18635: 18633: 18630: 18628: 18625: 18622: 18618: 18614: 18610: 18607: 18605: 18602: 18600: 18597: 18595: 18592: 18590: 18587: 18584: 18583: 18580: 18574: 18571: 18568: 18564: 18560: 18556: 18552: 18549: 18546: 18542: 18538: 18534: 18531: 18529: 18526: 18524: 18521: 18519: 18516: 18514: 18511: 18508: 18504: 18500: 18496: 18493: 18491: 18488: 18486: 18483: 18480: 18476: 18472: 18468: 18465: 18462: 18461: 18458: 18455: 18453: 18446: 18443: 18440: 18435: 18428: 18413: 18409: 18405: 18402: 18400: 18397: 18394: 18393: 18390: 18384: 18381: 18378: 18374: 18370: 18366: 18362: 18358: 18355: 18352: 18351:nortriptyline 18348: 18347:amitriptyline 18344: 18341: 18339: 18336: 18334: 18331: 18329: 18326: 18323: 18319: 18315: 18311: 18310:esmirtazapine 18307: 18303: 18299: 18296: 18294: 18293:Tedatioxetine 18291: 18289: 18286: 18284: 18281: 18279: 18276: 18274: 18271: 18269: 18266: 18264: 18261: 18259: 18256: 18254: 18251: 18249: 18246: 18244: 18241: 18239: 18236: 18234: 18231: 18229: 18226: 18224: 18221: 18219: 18216: 18214: 18211: 18209: 18206: 18204: 18201: 18199: 18196: 18194: 18191: 18189: 18186: 18184: 18181: 18179: 18176: 18173: 18169: 18165: 18161: 18157: 18153: 18149: 18148:bromocriptine 18145: 18141: 18138: 18136: 18133: 18131: 18128: 18126: 18125:Desmetramadol 18123: 18121: 18118: 18116: 18113: 18111: 18108: 18106: 18103: 18101: 18098: 18095: 18091: 18087: 18083: 18079: 18075: 18071: 18067: 18063: 18059: 18055: 18051: 18047: 18043: 18040: 18038: 18035: 18033: 18030: 18027: 18026: 18023: 18017: 18014: 18012: 18009: 18007: 18004: 18002: 17999: 17996: 17992: 17988: 17984: 17980: 17976: 17972: 17968: 17964: 17960: 17956: 17953: 17951: 17948: 17946: 17943: 17941: 17938: 17936: 17933: 17931: 17928: 17925: 17921: 17917: 17913: 17909: 17905: 17902: 17899: 17895: 17891: 17888: 17886: 17883: 17881: 17878: 17876: 17873: 17871: 17868: 17866: 17863: 17860: 17856: 17852: 17848: 17844: 17841: 17839: 17836: 17834: 17831: 17828: 17824: 17820: 17816: 17812: 17808: 17804: 17800: 17796: 17792: 17788: 17784: 17780: 17776: 17773: 17770: 17766: 17762: 17758: 17754: 17751: 17749: 17746: 17744: 17741: 17739: 17736: 17734: 17731: 17729: 17726: 17723: 17719: 17715: 17711: 17707: 17703: 17699: 17695: 17692: 17689: 17685: 17681: 17677: 17673: 17669: 17666: 17663: 17659: 17655: 17651: 17647: 17643: 17639: 17636: 17633: 17632: 17629: 17626: 17624: 17617: 17606: 17602: 17599: 17596: 17595: 17592: 17586: 17583: 17581: 17578: 17575: 17571: 17568: 17566: 17563: 17560: 17556: 17552: 17548: 17545: 17543: 17540: 17538: 17535: 17533: 17530: 17528: 17525: 17523: 17520: 17518: 17515: 17513: 17510: 17508: 17505: 17503: 17500: 17498: 17495: 17493: 17490: 17488: 17485: 17483: 17480: 17478: 17475: 17473: 17470: 17468: 17465: 17463: 17460: 17458: 17455: 17453: 17450: 17448: 17445: 17443: 17440: 17437: 17433: 17429: 17425: 17421: 17420:bromocriptine 17417: 17413: 17410: 17408: 17405: 17403: 17400: 17397: 17393: 17389: 17385: 17381: 17377: 17373: 17369: 17365: 17361: 17360:brexpiprazole 17357: 17353: 17349: 17345: 17342: 17340: 17337: 17334: 17333: 17330: 17323: 17319: 17315: 17311: 17307: 17303: 17299: 17295: 17291: 17287: 17283: 17279: 17275: 17272: 17270: 17267: 17265: 17262: 17260: 17257: 17254: 17250: 17247: 17244: 17240: 17236: 17232: 17228: 17225: 17223: 17220: 17217: 17213: 17209: 17205: 17201: 17197: 17193: 17189: 17186: 17183: 17179: 17175: 17171: 17167: 17164: 17162: 17159: 17156: 17152: 17148: 17144: 17140: 17136: 17132: 17129: 17127: 17124: 17122: 17119: 17116: 17115: 17112: 17109: 17107: 17100: 17089: 17085: 17081: 17078: 17075: 17074: 17071: 17065: 17062: 17060: 17057: 17055: 17052: 17049: 17045: 17041: 17037: 17033: 17029: 17025: 17021: 17017: 17013: 17009: 17005: 17001: 16997: 16993: 16990: 16987: 16986:amitriptyline 16983: 16980: 16977: 16973: 16969: 16965: 16964:esmirtazapine 16961: 16957: 16953: 16950: 16948: 16945: 16943: 16940: 16938: 16935: 16933: 16930: 16927: 16923: 16922:triazoledione 16919: 16915: 16911: 16907: 16903: 16899: 16896: 16894: 16891: 16889: 16886: 16884: 16881: 16879: 16876: 16874: 16871: 16869: 16866: 16864: 16861: 16859: 16856: 16854: 16851: 16849: 16846: 16844: 16841: 16839: 16836: 16834: 16831: 16829: 16826: 16824: 16823:Naftidrofuryl 16821: 16819: 16816: 16814: 16811: 16809: 16806: 16804: 16801: 16799: 16796: 16794: 16791: 16789: 16786: 16784: 16781: 16779: 16776: 16774: 16771: 16769: 16766: 16764: 16761: 16758: 16754: 16750: 16746: 16742: 16738: 16734: 16730: 16727: 16725: 16722: 16720: 16717: 16715: 16712: 16710: 16707: 16705: 16702: 16700: 16697: 16694: 16690: 16686: 16682: 16678: 16674: 16670: 16666: 16662: 16658: 16654: 16650: 16646: 16642: 16638: 16634: 16630: 16626: 16622: 16618: 16617:brexpiprazole 16614: 16610: 16606: 16602: 16598: 16595: 16593: 16590: 16587: 16583: 16579: 16575: 16571: 16568: 16566: 16563: 16561: 16558: 16556: 16553: 16551: 16548: 16546: 16543: 16540: 16539: 16536: 16529: 16525: 16521: 16517: 16513: 16509: 16505: 16501: 16497: 16493: 16489: 16486: 16484: 16481: 16479: 16476: 16474: 16471: 16468: 16464: 16460: 16456: 16453: 16450: 16446: 16442: 16439: 16437: 16434: 16432: 16429: 16427: 16424: 16422: 16419: 16417: 16414: 16412: 16409: 16407: 16404: 16401: 16397: 16393: 16389: 16385: 16382: 16380: 16377: 16375: 16372: 16370: 16367: 16365: 16362: 16359: 16355: 16351: 16347: 16343: 16339: 16335: 16331: 16327: 16323: 16319: 16315: 16311: 16307: 16306:bromocriptine 16303: 16299: 16295: 16292: 16290: 16287: 16284: 16280: 16276: 16272: 16268: 16265: 16263: 16260: 16258: 16255: 16253: 16250: 16248: 16245: 16243: 16240: 16237: 16233: 16229: 16225: 16221: 16217: 16213: 16209: 16206: 16203: 16199: 16195: 16191: 16187: 16183: 16180: 16178: 16175: 16173: 16170: 16167: 16163: 16159: 16155: 16151: 16147: 16143: 16140: 16137: 16133: 16129: 16125: 16121: 16117: 16113: 16109: 16105: 16101: 16097: 16094: 16093: 16090: 16087: 16085: 16078: 16075: 16073: 16066: 16052: 16049: 16047: 16044: 16041: 16040: 16037: 16030: 16026: 16023: 16020: 16016: 16012: 16008: 16005: 16003: 16000: 15998: 15995: 15993: 15990: 15987: 15984: 15980: 15976: 15975:bromocriptine 15972: 15969: 15967: 15964: 15962: 15959: 15956: 15955: 15952: 15949: 15947: 15940: 15930: 15926: 15922: 15918: 15915: 15912: 15911: 15908: 15902: 15899: 15896: 15895: 15892: 15885: 15881: 15878: 15875: 15871: 15868: 15866: 15863: 15860: 15856: 15853: 15851: 15848: 15845: 15844: 15841: 15838: 15836: 15829: 15818: 15814: 15810: 15806: 15803: 15801: 15798: 15795: 15794: 15791: 15785: 15782: 15780: 15777: 15775: 15772: 15770: 15767: 15765: 15762: 15760: 15757: 15755: 15752: 15750: 15747: 15745: 15742: 15740: 15737: 15735: 15732: 15730: 15727: 15724: 15720: 15717: 15715: 15712: 15710: 15707: 15705: 15702: 15699: 15698: 15695: 15688: 15684: 15680: 15676: 15672: 15668: 15664: 15661: 15658: 15654: 15650: 15646: 15642: 15638: 15634: 15630: 15626: 15622: 15619: 15617: 15614: 15612: 15609: 15607: 15604: 15602: 15599: 15597: 15594: 15592: 15589: 15587: 15584: 15582: 15579: 15576: 15572: 15568: 15564: 15560: 15556: 15555:bromocriptine 15552: 15549: 15547: 15544: 15542: 15539: 15537: 15534: 15531: 15530: 15527: 15524: 15522: 15515: 15504: 15500: 15496: 15492: 15489: 15486: 15485: 15482: 15476: 15473: 15471: 15468: 15466: 15463: 15461: 15458: 15456: 15453: 15451: 15448: 15446: 15443: 15441: 15438: 15435: 15431: 15428: 15426: 15423: 15420: 15416: 15412: 15408: 15404: 15400: 15396: 15392: 15391:Beta blockers 15389: 15387: 15384: 15381: 15380: 15377: 15371: 15368: 15365: 15361: 15357: 15353: 15349: 15346: 15344: 15341: 15338: 15334: 15330: 15326: 15322: 15318: 15315: 15313: 15310: 15308: 15305: 15303: 15300: 15297: 15293: 15289: 15285: 15281: 15277: 15276:bromocriptine 15273: 15270: 15268: 15265: 15263: 15260: 15258: 15255: 15253: 15250: 15248: 15245: 15243: 15240: 15238: 15235: 15232: 15231: 15228: 15225: 15223: 15216: 15205: 15201: 15198: 15196: 15193: 15191: 15188: 15185: 15184: 15181: 15175: 15172: 15170: 15167: 15165: 15162: 15160: 15157: 15155: 15152: 15150: 15147: 15145: 15142: 15140: 15137: 15135: 15132: 15130: 15127: 15125: 15122: 15120: 15117: 15115: 15112: 15110: 15107: 15105: 15102: 15100: 15097: 15095: 15092: 15090: 15087: 15085: 15082: 15080: 15077: 15075: 15072: 15069: 15065: 15062: 15060: 15057: 15055: 15052: 15050: 15047: 15044: 15040: 15036: 15032: 15028: 15024: 15020: 15016: 15012: 15011:cyanopindolol 15008: 15004: 15000: 14999:Beta blockers 14997: 14995: 14992: 14989: 14985: 14981: 14977: 14974: 14971: 14970: 14967: 14961: 14958: 14956: 14953: 14951: 14948: 14946: 14943: 14941: 14938: 14936: 14933: 14930: 14926: 14922: 14918: 14914: 14910: 14906: 14902: 14898: 14894: 14891: 14889: 14886: 14884: 14881: 14879: 14876: 14874: 14871: 14869: 14866: 14864: 14861: 14859: 14856: 14854: 14851: 14849: 14846: 14844: 14841: 14839: 14836: 14834: 14831: 14829: 14826: 14824: 14821: 14819: 14816: 14814: 14811: 14809: 14806: 14804: 14801: 14799: 14796: 14794: 14791: 14789: 14786: 14784: 14781: 14779: 14776: 14774: 14771: 14769: 14766: 14764: 14761: 14759: 14756: 14754: 14751: 14749: 14746: 14744: 14741: 14739: 14736: 14734: 14731: 14728: 14724: 14720: 14716: 14712: 14708: 14704: 14700: 14696: 14695:bromocriptine 14692: 14689: 14687: 14684: 14682: 14679: 14677: 14674: 14672: 14669: 14667: 14664: 14662: 14659: 14657: 14654: 14652: 14649: 14647: 14644: 14641: 14637: 14633: 14629: 14625: 14621: 14618: 14615: 14611: 14607: 14603: 14599: 14595: 14594:brexpiprazole 14591: 14587: 14583: 14580: 14577: 14573: 14569: 14568:triazoledione 14565: 14561: 14557: 14553: 14549: 14546: 14544: 14541: 14539: 14536: 14534: 14531: 14528: 14527: 14524: 14521: 14519: 14512: 14509: 14507: 14500: 14496: 14493: 14486: 14481: 14479: 14474: 14472: 14467: 14466: 14463: 14450: 14449: 14444: 14441: 14440: 14435: 14432: 14431: 14426: 14423: 14422: 14417: 14414: 14413: 14412:Serotonergics 14408: 14405: 14404: 14399: 14396: 14395: 14392: 14387: 14386: 14383: 14373: 14370: 14368: 14365: 14363: 14360: 14358: 14355: 14353: 14350: 14348: 14345: 14343: 14340: 14338: 14335: 14333: 14332:Sonepiprazole 14330: 14328: 14325: 14323: 14320: 14318: 14315: 14313: 14310: 14308: 14305: 14303: 14300: 14298: 14295: 14293: 14290: 14288: 14285: 14283: 14280: 14278: 14275: 14273: 14270: 14268: 14265: 14263: 14260: 14258: 14255: 14253: 14250: 14248: 14247:Iodobenzamide 14245: 14243: 14240: 14238: 14235: 14233: 14230: 14228: 14225: 14223: 14220: 14218: 14215: 14213: 14210: 14208: 14207:Bromocriptine 14205: 14203: 14200: 14198: 14195: 14193: 14190: 14188: 14184: 14181: 14180: 14177: 14174: 14172: 14169: 14167: 14164: 14162: 14159: 14157: 14153: 14150: 14149: 14146: 14143: 14141: 14138: 14136: 14133: 14131: 14128: 14126: 14123: 14121: 14118: 14116: 14113: 14111: 14108: 14106: 14103: 14101: 14098: 14096: 14093: 14091: 14088: 14086: 14083: 14081: 14080:Benzquinamide 14078: 14076: 14073: 14071: 14068: 14066: 14063: 14061: 14057: 14054: 14053: 14050: 14047: 14045: 14042: 14040: 14037: 14035: 14032: 14030: 14027: 14025: 14022: 14020: 14017: 14015: 14012: 14010: 14007: 14005: 14002: 14000: 13997: 13995: 13992: 13990: 13987: 13985: 13982: 13980: 13977: 13975: 13972: 13969: 13965: 13962: 13960: 13957: 13955: 13952: 13950: 13947: 13945: 13942: 13940: 13937: 13935: 13932: 13930: 13927: 13925: 13922: 13920: 13917: 13915: 13912: 13910: 13907: 13905: 13902: 13900: 13899:DHA-clozapine 13897: 13895: 13892: 13890: 13887: 13885: 13882: 13880: 13877: 13875: 13872: 13870: 13867: 13865: 13862: 13860: 13857: 13855: 13852: 13850: 13847: 13845: 13841: 13838: 13837: 13834: 13831: 13829: 13826: 13824: 13823:Trifluperidol 13821: 13819: 13816: 13813: 13809: 13806: 13804: 13801: 13799: 13796: 13794: 13791: 13789: 13786: 13784: 13783:Thiopropazate 13781: 13779: 13776: 13774: 13771: 13769: 13766: 13764: 13763:Sulforidazine 13761: 13759: 13756: 13754: 13751: 13749: 13746: 13744: 13741: 13739: 13736: 13734: 13731: 13729: 13726: 13724: 13721: 13718: 13714: 13711: 13709: 13706: 13704: 13701: 13699: 13696: 13694: 13691: 13689: 13686: 13684: 13681: 13679: 13676: 13674: 13671: 13669: 13666: 13664: 13663:Levosulpiride 13661: 13659: 13656: 13654: 13651: 13649: 13646: 13644: 13641: 13639: 13636: 13634: 13633:Fluprothixene 13631: 13629: 13626: 13623: 13619: 13616: 13614: 13611: 13609: 13606: 13604: 13601: 13599: 13596: 13594: 13591: 13589: 13586: 13584: 13581: 13579: 13576: 13574: 13571: 13569: 13566: 13564: 13561: 13559: 13556: 13554: 13551: 13549: 13546: 13544: 13541: 13539: 13536: 13534: 13531: 13529: 13526: 13524: 13521: 13519: 13515: 13512: 13511: 13509: 13505: 13499: 13496: 13494: 13491: 13489: 13486: 13484: 13481: 13479: 13476: 13474: 13471: 13469: 13466: 13464: 13461: 13459: 13456: 13454: 13451: 13449: 13446: 13444: 13441: 13439: 13436: 13434: 13431: 13429: 13426: 13424: 13421: 13419: 13416: 13414: 13411: 13409: 13408:Phencyclidine 13406: 13404: 13401: 13399: 13396: 13394: 13391: 13389: 13386: 13384: 13381: 13379: 13376: 13374: 13371: 13369: 13366: 13364: 13361: 13359: 13356: 13354: 13351: 13349: 13346: 13344: 13341: 13339: 13336: 13334: 13331: 13329: 13326: 13324: 13321: 13319: 13316: 13314: 13311: 13309: 13306: 13304: 13301: 13299: 13296: 13294: 13291: 13289: 13285: 13282: 13281: 13278: 13275: 13273: 13270: 13268: 13265: 13263: 13260: 13258: 13257:Brilaroxazine 13255: 13253: 13252:Brexpiprazole 13250: 13248: 13245: 13243: 13240: 13237: 13233: 13230: 13228: 13224: 13221: 13220: 13217: 13214: 13212: 13209: 13207: 13201: 13199: 13193: 13191: 13185: 13183: 13180: 13178: 13175: 13173: 13170: 13168: 13164: 13161: 13160: 13157: 13154: 13152: 13149: 13147: 13146:Dihydrexidine 13144: 13142: 13139: 13137: 13133: 13130: 13129: 13126: 13123: 13121: 13118: 13116: 13113: 13111: 13108: 13106: 13103: 13101: 13098: 13096: 13093: 13091: 13088: 13086: 13083: 13081: 13078: 13076: 13075:Bromocriptine 13072: 13069: 13068: 13065: 13062: 13060: 13057: 13055: 13052: 13050: 13047: 13045: 13041: 13038: 13037: 13034: 13031: 13029: 13026: 13024: 13020: 13017: 13016: 13014: 13010: 13007: 13005: 12997: 12987: 12984: 12982: 12979: 12977: 12974: 12972: 12969: 12967: 12964: 12962: 12959: 12957: 12953: 12950: 12949: 12946: 12943: 12941: 12938: 12936: 12933: 12931: 12928: 12926: 12923: 12921: 12918: 12916: 12913: 12910: 12906: 12903: 12901: 12900:Norquetiapine 12898: 12896: 12893: 12891: 12888: 12886: 12883: 12881: 12880:DHA-clozapine 12878: 12876: 12873: 12871: 12868: 12866: 12863: 12861: 12857: 12854: 12853: 12850: 12847: 12844: 12840: 12837: 12835: 12832: 12830: 12827: 12825: 12822: 12819: 12815: 12812: 12810: 12807: 12805: 12802: 12799: 12795: 12792: 12790: 12787: 12785: 12782: 12780: 12776: 12773: 12772: 12770: 12766: 12760: 12757: 12755: 12752: 12750: 12746: 12743: 12742: 12740: 12736: 12730: 12727: 12725: 12722: 12720: 12717: 12715: 12712: 12710: 12707: 12705: 12702: 12700: 12697: 12695: 12692: 12690: 12687: 12685: 12682: 12680: 12677: 12675: 12672: 12670: 12666: 12663: 12662: 12659: 12656: 12654: 12648: 12646: 12640: 12638: 12635: 12633: 12627: 12625: 12622: 12620: 12617: 12615: 12612: 12610: 12607: 12605: 12601: 12598: 12597: 12594: 12591: 12589: 12586: 12584: 12581: 12579: 12578:Dihydrexidine 12576: 12574: 12571: 12569: 12566: 12564: 12560: 12557: 12556: 12553: 12550: 12548: 12545: 12543: 12540: 12538: 12535: 12533: 12530: 12528: 12525: 12523: 12519: 12516: 12515: 12512: 12509: 12507: 12504: 12502: 12499: 12497: 12494: 12492: 12489: 12487: 12484: 12482: 12479: 12477: 12474: 12472: 12468: 12465: 12464: 12462: 12458: 12455: 12453: 12445: 12441: 12438: 12431: 12426: 12424: 12419: 12417: 12412: 12411: 12408: 12392: 12390: 12387: 12386: 12384: 12381: 12378: 12375: 12373: 12370: 12369: 12365: 12359: 12356: 12353: 12352: 12349: 12348:Tetrabenazine 12346: 12344: 12341: 12339: 12336: 12334: 12330: 12329: 12327: 12323: 12317: 12314: 12312: 12309: 12307: 12304: 12301: 12300: 12297: 12294: 12292: 12289: 12286: 12282: 12279: 12277: 12274: 12272: 12269: 12267: 12263: 12262: 12259: 12256: 12254: 12253:Brexpiprazole 12251: 12249: 12248:Brilaroxazine 12246: 12242: 12239: 12238: 12237: 12234: 12232: 12228: 12224: 12223: 12220: 12217: 12215: 12211: 12210: 12207: 12204: 12202: 12199: 12197: 12194: 12190: 12187: 12186: 12185: 12182: 12180: 12177: 12175: 12172: 12170: 12166: 12165:Benzisoxazole 12162: 12161: 12159: 12157: 12153: 12147: 12144: 12141: 12140: 12137: 12134: 12132: 12129: 12127: 12124: 12122: 12119: 12117: 12114: 12112: 12109: 12107: 12104: 12102: 12098: 12097: 12094: 12091: 12089: 12085: 12084: 12081: 12078: 12076: 12073: 12071: 12068: 12066: 12063: 12061: 12058: 12056: 12053: 12051: 12050:Levosulpiride 12048: 12046: 12043: 12041: 12037: 12036: 12034: 12030: 12022: 12019: 12017: 12014: 12013: 12012: 12009: 12007: 12004: 12000: 11997: 11996: 11995: 11992: 11988: 11985: 11984: 11983: 11980: 11978: 11975: 11973: 11972:Thioxanthenes 11969: 11968: 11965: 11962: 11960: 11957: 11955: 11952: 11950: 11947: 11945: 11944:Thiopropazate 11942: 11940: 11939:Sulforidazine 11937: 11935: 11932: 11930: 11927: 11923: 11920: 11918: 11915: 11914: 11913: 11910: 11908: 11905: 11901: 11898: 11896: 11893: 11891: 11888: 11887: 11886: 11883: 11881: 11878: 11876: 11873: 11871: 11868: 11866: 11863: 11859: 11856: 11854: 11851: 11850: 11849: 11846: 11844: 11841: 11839: 11836: 11834: 11831: 11829: 11826: 11824: 11821: 11819: 11816: 11814: 11811: 11809: 11805: 11804: 11801: 11798: 11796: 11793: 11791: 11788: 11786: 11782: 11781: 11778: 11777:Trifluperidol 11775: 11773: 11770: 11768: 11765: 11763: 11760: 11758: 11755: 11751: 11748: 11747: 11746: 11743: 11741: 11738: 11734: 11731: 11730: 11729: 11726: 11724: 11721: 11719: 11715: 11714: 11712: 11710: 11706: 11701: 11697: 11690: 11685: 11683: 11678: 11676: 11671: 11670: 11667: 11660: 11655: 11651: 11650: 11631: 11627: 11623: 11619: 11617: 11614: 11610: 11606: 11602: 11598: 11593: 11578: 11574: 11570: 11566: 11562: 11559:(3): 857–62. 11558: 11554: 11547: 11542: 11541: 11520: 11516: 11510: 11495: 11491: 11485: 11469: 11465: 11461: 11455: 11438: 11434: 11430: 11424: 11422: 11405: 11401: 11397: 11391: 11375: 11371: 11365: 11357: 11353: 11349: 11345: 11340: 11335: 11331: 11327: 11323: 11316: 11308: 11304: 11299: 11294: 11290: 11286: 11282: 11275: 11267: 11263: 11259: 11255: 11251: 11247: 11243: 11239: 11232: 11224: 11220: 11215: 11210: 11206: 11202: 11199:(6): 268–74. 11198: 11194: 11190: 11183: 11176:(6): 1071–88. 11175: 11171: 11164: 11156: 11152: 11148: 11144: 11141:(4): 238–46. 11140: 11136: 11129: 11121: 11117: 11113: 11109: 11105: 11101: 11094: 11086: 11082: 11078: 11074: 11066: 11058: 11051: 11043: 11039: 11034: 11029: 11025: 11021: 11018:(4): 325–31. 11017: 11013: 11009: 11002: 11000: 10991: 10987: 10983: 10979: 10972: 10964: 10957: 10955: 10946: 10942: 10938: 10934: 10930: 10926: 10919: 10917: 10908: 10904: 10897: 10889: 10885: 10881: 10877: 10873: 10869: 10862: 10853: 10845: 10841: 10837: 10833: 10829: 10825: 10821: 10817: 10810: 10801: 10793: 10789: 10785: 10781: 10777: 10773: 10769: 10765: 10758: 10743: 10739: 10733: 10718: 10714: 10708: 10693: 10692: 10687: 10681: 10672: 10656: 10652: 10648: 10645:, Driscol J. 10644: 10638: 10630: 10626: 10622: 10618: 10614: 10610: 10603: 10595: 10591: 10587: 10583: 10579: 10575: 10571: 10567: 10563: 10557: 10549: 10545: 10540: 10535: 10531: 10527: 10523: 10516: 10508: 10504: 10500: 10496: 10492: 10488: 10485:(1–2): 71–6. 10484: 10480: 10473: 10465: 10461: 10457: 10453: 10450:(3): 213–23. 10449: 10445: 10438: 10427:September 30, 10422: 10415: 10409: 10401: 10395: 10391: 10390: 10382: 10371:September 30, 10367: 10365:9781455728886 10361: 10357: 10356: 10348: 10337:September 30, 10333: 10327: 10323: 10322: 10314: 10298: 10294: 10287: 10279: 10275: 10271: 10267: 10263: 10259: 10256:(1): 171–81. 10255: 10251: 10243: 10232:September 30, 10228: 10221: 10215: 10213: 10204: 10200: 10196: 10192: 10188: 10184: 10180: 10176: 10169: 10161: 10157: 10153: 10149: 10146:(9): 482–92. 10145: 10141: 10134: 10123:September 30, 10119: 10117:9780521886642 10113: 10109: 10108: 10100: 10089:September 30, 10085: 10081: 10075: 10064:September 30, 10060: 10056: 10050: 10039:September 30, 10034: 10030: 10024: 10013:September 30, 10008: 10004: 10000: 9994: 9983:September 30, 9978: 9974: 9968: 9957:September 30, 9952: 9948: 9947:Boundless.com 9944: 9938: 9927:September 30, 9923: 9921:9781597453110 9917: 9913: 9912: 9904: 9893:September 30, 9888: 9884: 9878: 9870: 9866: 9862: 9858: 9854: 9850: 9843: 9835: 9831: 9827: 9823: 9819: 9815: 9812:(4): 487–96. 9811: 9807: 9800: 9789:September 30, 9785: 9783:9780521886642 9779: 9775: 9774: 9766: 9755: 9748: 9747: 9739: 9737: 9735: 9733: 9731: 9729: 9720: 9714: 9710: 9709: 9701: 9693: 9691:9788847026797 9687: 9683: 9682: 9674: 9666: 9662: 9658: 9654: 9650: 9646: 9642: 9638: 9631: 9623: 9621:9780198527480 9617: 9613: 9612: 9604: 9602: 9600: 9598: 9596: 9588: 9584: 9578: 9574: 9567: 9556:September 30, 9551: 9550:Allnurses.com 9547: 9541: 9533: 9529: 9525: 9521: 9517: 9513: 9510:(6): 445–56. 9509: 9505: 9498: 9490: 9486: 9482: 9478: 9474: 9470: 9466: 9462: 9455: 9453: 9451: 9449: 9447: 9438: 9434: 9429: 9424: 9420: 9416: 9412: 9408: 9404: 9397: 9395: 9378: 9373: 9366: 9364: 9362: 9360: 9358: 9356: 9354: 9352: 9350: 9348: 9346: 9344: 9342: 9340: 9338: 9336: 9334: 9332: 9330: 9328: 9326: 9324: 9322: 9320: 9318: 9316: 9314: 9312: 9310: 9308: 9306: 9304: 9302: 9300: 9298: 9296: 9294: 9292: 9290: 9288: 9286: 9284: 9282: 9280: 9278: 9276: 9274: 9272: 9270: 9268: 9266: 9264: 9262: 9260: 9258: 9256: 9254: 9252: 9250: 9248: 9239: 9235: 9230: 9225: 9220: 9215: 9210: 9205: 9201: 9197: 9193: 9186: 9178: 9174: 9170: 9166: 9162: 9158: 9155:(9): 1111–9. 9154: 9150: 9142: 9133: 9128: 9124: 9120: 9116: 9112: 9108: 9101: 9093: 9089: 9084: 9079: 9074: 9069: 9066:: 2231–2241. 9065: 9061: 9057: 9050: 9042: 9038: 9034: 9030: 9025: 9020: 9016: 9012: 9007: 9002: 8998: 8994: 8990: 8983: 8975: 8971: 8967: 8963: 8959: 8955: 8950: 8945: 8941: 8937: 8933: 8926: 8918: 8914: 8910: 8906: 8902: 8898: 8894: 8890: 8882: 8874: 8867: 8859: 8855: 8850: 8845: 8841: 8837: 8836:Diabetes Care 8833: 8827: 8825: 8823: 8814: 8810: 8806: 8802: 8798: 8794: 8790: 8786: 8779: 8777: 8768: 8764: 8759: 8754: 8750: 8746: 8742: 8735: 8733: 8731: 8729: 8727: 8725: 8723: 8714: 8710: 8705: 8700: 8696: 8692: 8688: 8684: 8680: 8676: 8672: 8665: 8657: 8653: 8649: 8645: 8641: 8637: 8633: 8629: 8625: 8621: 8614: 8606: 8602: 8597: 8592: 8588: 8584: 8579: 8574: 8570: 8566: 8562: 8555: 8547: 8543: 8539: 8535: 8530: 8525: 8521: 8517: 8513: 8506: 8498: 8494: 8489: 8484: 8480: 8476: 8472: 8468: 8464: 8457: 8449: 8445: 8440: 8435: 8431: 8427: 8423: 8416: 8408: 8404: 8399: 8394: 8390: 8386: 8383:(1): 96–103. 8382: 8378: 8374: 8367: 8359: 8355: 8351: 8345: 8341: 8340: 8332: 8330: 8328: 8326: 8324: 8322: 8320: 8318: 8316: 8314: 8312: 8303: 8299: 8294: 8289: 8285: 8281: 8277: 8273: 8269: 8262: 8254: 8250: 8245: 8240: 8236: 8232: 8228: 8224: 8220: 8213: 8211: 8209: 8207: 8205: 8188: 8184: 8177: 8169: 8165: 8161: 8157: 8153: 8149: 8146:(9): 731–41. 8145: 8141: 8134: 8126: 8122: 8117: 8112: 8107: 8102: 8098: 8094: 8090: 8083: 8075: 8071: 8067: 8063: 8059: 8055: 8052:(6): 452–69. 8051: 8047: 8040: 8038: 8036: 8034: 8032: 8030: 8021: 8017: 8012: 8007: 8002: 7997: 7993: 7989: 7985: 7978: 7970: 7966: 7962: 7958: 7954: 7950: 7946: 7942: 7934: 7926: 7922: 7917: 7912: 7908: 7904: 7900: 7893: 7891: 7882: 7878: 7873: 7868: 7864: 7860: 7856: 7849: 7847: 7845: 7843: 7827: 7823: 7817: 7802: 7798: 7792: 7784: 7780: 7776: 7772: 7768: 7764: 7761:(3): 179–88. 7760: 7756: 7749: 7747: 7738: 7734: 7730: 7726: 7722: 7718: 7715:(4): 365–73. 7714: 7710: 7702: 7693: 7691: 7682: 7678: 7673: 7668: 7663: 7658: 7654: 7650: 7646: 7639: 7631: 7627: 7622: 7617: 7613: 7609: 7605: 7601: 7597: 7590: 7575: 7571: 7568:Research Cf. 7564: 7556: 7552: 7547: 7542: 7539:(9): 980–91. 7538: 7534: 7530: 7523: 7515: 7511: 7506: 7501: 7496: 7491: 7487: 7483: 7482:PLOS Medicine 7479: 7472: 7470: 7461: 7457: 7453: 7449: 7445: 7438: 7436: 7419: 7415: 7408: 7392: 7388: 7381: 7373: 7366: 7364: 7362: 7346: 7342: 7336: 7328: 7322: 7318: 7314: 7313: 7305: 7297: 7293: 7289: 7285: 7281: 7277: 7274:(1–2): 80–7. 7273: 7269: 7261: 7252: 7247: 7243: 7239: 7235: 7228: 7220: 7216: 7212: 7208: 7205:(3): 137–46. 7204: 7200: 7193: 7185: 7181: 7177: 7173: 7169: 7165: 7161: 7157: 7150: 7142: 7138: 7134: 7130: 7127:(4): 611–22. 7126: 7122: 7114: 7106: 7102: 7097: 7092: 7088: 7084: 7080: 7073: 7065: 7061: 7056: 7051: 7047: 7043: 7039: 7035: 7031: 7024: 7016: 7012: 7007: 7002: 6998: 6994: 6991:(2): 177–84. 6990: 6986: 6982: 6975: 6967: 6963: 6958: 6953: 6949: 6945: 6941: 6937: 6933: 6929: 6925: 6921: 6914: 6906: 6902: 6897: 6892: 6888: 6884: 6880: 6876: 6872: 6868: 6864: 6857: 6849: 6845: 6840: 6835: 6831: 6827: 6823: 6816: 6808: 6804: 6800: 6796: 6789: 6781: 6777: 6773: 6769: 6762: 6754: 6750: 6745: 6740: 6736: 6732: 6729:(3): 345–57. 6728: 6724: 6720: 6713: 6705: 6701: 6697: 6693: 6689: 6685: 6681: 6677: 6670: 6662: 6658: 6653: 6648: 6644: 6640: 6636: 6629: 6621: 6617: 6612: 6607: 6603: 6599: 6595: 6591: 6587: 6580: 6572: 6568: 6564: 6560: 6556: 6552: 6548: 6544: 6537: 6530: 6514: 6507: 6501: 6493: 6487: 6479: 6475: 6470: 6465: 6461: 6457: 6454:(4): 616–31. 6453: 6449: 6445: 6438: 6430: 6424: 6420: 6413: 6405: 6401: 6396: 6391: 6387: 6383: 6379: 6372: 6357: 6353: 6352:"Respiridone" 6347: 6339: 6335: 6331: 6327: 6323: 6319: 6316:(9657): 4–5. 6315: 6311: 6304: 6296: 6292: 6287: 6282: 6278: 6274: 6270: 6266: 6262: 6256: 6248: 6244: 6240: 6236: 6232: 6228: 6224: 6220: 6212: 6210: 6208: 6199: 6195: 6191: 6187: 6183: 6179: 6175: 6171: 6164: 6162: 6160: 6158: 6149: 6145: 6141: 6135: 6131: 6124: 6116: 6112: 6108: 6104: 6101:(3): 122–33. 6100: 6096: 6089: 6085: 6076: 6073: 6072: 6058: 6056: 6054: 6052: 6042: 6040: 6038: 6028: 6026: 6021: 6018: 6017: 6004: 5994: 5990: 5977: 5974: 5971: 5968: 5965: 5962: 5960: 5957: 5956: 5952: 5949: 5946: 5943: 5940: 5937: 5935: 5932: 5931: 5927: 5924: 5921: 5918: 5915: 5912: 5910: 5907: 5906: 5902: 5899: 5896: 5893: 5890: 5887: 5885: 5882: 5881: 5877: 5874: 5871: 5868: 5865: 5862: 5860: 5857: 5856: 5852: 5849: 5846: 5843: 5840: 5837: 5835: 5832: 5831: 5827: 5824: 5821: 5818: 5815: 5812: 5810: 5807: 5806: 5802: 5799: 5796: 5793: 5790: 5787: 5785: 5782: 5781: 5777: 5774: 5771: 5768: 5765: 5762: 5760: 5757: 5756: 5752: 5749: 5746: 5743: 5740: 5737: 5735: 5732: 5731: 5727: 5724: 5721: 5718: 5715: 5712: 5710: 5707: 5706: 5702: 5699: 5696: 5693: 5690: 5687: 5685: 5682: 5681: 5677: 5674: 5671: 5668: 5665: 5662: 5660: 5657: 5656: 5652: 5649: 5646: 5643: 5640: 5637: 5635: 5632: 5631: 5627: 5624: 5621: 5618: 5615: 5612: 5610: 5607: 5606: 5602: 5599: 5596: 5593: 5590: 5587: 5585: 5582: 5581: 5577: 5574: 5571: 5568: 5565: 5562: 5560: 5557: 5556: 5552: 5549: 5546: 5543: 5540: 5537: 5535: 5532: 5531: 5527: 5524: 5521: 5518: 5515: 5512: 5510: 5507: 5506: 5502: 5499: 5496: 5493: 5490: 5487: 5485: 5482: 5481: 5477: 5474: 5471: 5468: 5465: 5462: 5460: 5457: 5456: 5452: 5449: 5446: 5443: 5440: 5437: 5435: 5432: 5431: 5427: 5420: 5417: 5410: 5407: 5400: 5397: 5390: 5387: 5380: 5377: 5372:United States 5370: 5367: 5366: 5359: 5351: 5349: 5344: 5335: 5333: 5329: 5324: 5320: 5318: 5314: 5310: 5305: 5303: 5299: 5295: 5291: 5287: 5283: 5278: 5277:schizophrenia 5274: 5270: 5255: 5252: 5248: 5244: 5240: 5236: 5232: 5231:vegetable oil 5229: 5225: 5222: 5218: 5214: 5210: 5206: 5202: 5199: 5196: 5193: 5190: 5188:4–9 days 5187: 5184: 5182: 5179: 5177: 5174: 5171: 5169: 5166: 5165: 5162: 5159: 5154:1–2 days 5153: 5150: 5148: 5145: 5143: 5140: 5137: 5135: 5132: 5131: 5128: 5125: 5123:3–6 days 5122: 5119: 5116: 5113: 5111: 5108: 5105: 5102: 5100: 5097: 5096: 5093: 5090: 5087: 5084: 5081: 5078: 5076: 5073: 5071: 5068: 5065: 5063: 5060: 5059: 5056: 5053: 5050: 5047: 5044: 5041: 5039: 5036: 5034: 5031: 5028: 5026: 5023: 5022: 5019: 5016: 5014:4–7 days 5013: 5010: 5008:2–3 days 5007: 5004: 5002: 4999: 4997: 4994: 4991: 4989: 4986: 4985: 4982: 4979: 4976: 4973: 4970: 4967: 4965: 4962: 4960: 4957: 4954: 4952: 4949: 4948: 4945: 4942: 4939: 4936: 4933: 4930: 4928: 4925: 4922: 4919: 4917: 4914: 4913: 4910: 4907: 4904: 4901: 4898: 4895: 4892: 4890: 4887: 4884: 4882: 4879: 4878: 4875: 4872: 4869: 4866: 4863: 4860: 4858: 4855: 4852: 4849: 4847: 4844: 4843: 4840: 4837: 4832:3–9 days 4831: 4828: 4826: 4823: 4821: 4818: 4815: 4813: 4810: 4809: 4806: 4803: 4800: 4797: 4795:1–8 days 4794: 4791: 4789: 4786: 4784: 4781: 4778: 4776: 4773: 4772: 4769: 4766: 4763: 4760: 4758:2–3 days 4757: 4754: 4752: 4749: 4747: 4744: 4741: 4739: 4736: 4735: 4732: 4729: 4726: 4723: 4721:1–2 days 4720: 4717: 4715: 4712: 4710: 4707: 4704: 4702: 4699: 4698: 4695: 4692: 4689: 4686: 4683: 4680: 4678: 4675: 4673: 4670: 4667: 4665: 4662: 4661: 4658: 4655: 4652: 4649: 4647:4–7 days 4646: 4643: 4641: 4638: 4636: 4633: 4630: 4628: 4625: 4624: 4621: 4618: 4615: 4612: 4610:3–9 days 4609: 4606: 4604: 4601: 4599: 4596: 4593: 4591: 4588: 4587: 4584: 4581: 4578: 4575: 4572: 4569: 4567: 4564: 4561: 4558: 4556: 4553: 4552: 4549: 4546: 4543: 4540: 4537: 4534: 4532: 4529: 4526: 4523: 4521: 4518: 4517: 4513: 4510: 4503: 4496: 4490: 4487: 4484: 4481: 4478: 4475: 4474: 4465: 4460: 4458: 4453: 4451: 4446: 4445: 4437: 4422: 4417: 4413: 4410: 4407: 4404: 4401: 4398: 4395: 4392: 4389: 4387: 4384: 4383: 4379: 4376: 4373: 4371: 4367: 4364: 4361: 4358: 4355: 4352: 4349: 4347: 4344: 4343: 4339: 4336: 4333: 4331: 4328: 4325: 4322: 4319: 4316: 4313: 4311: 4308: 4307: 4303: 4300: 4297: 4295: 4292: 4289: 4286: 4283: 4280: 4277: 4275: 4272: 4271: 4267: 4264: 4261: 4259: 4256: 4253: 4250: 4247: 4244: 4241: 4239: 4236: 4235: 4231: 4228: 4225: 4222: 4219: 4216: 4213: 4210: 4207: 4205: 4202: 4201: 4197: 4194: 4191: 4189: 4185: 4182: 4179: 4176: 4173: 4170: 4167: 4165: 4162: 4161: 4157: 4154: 4151: 4149: 4145: 4142: 4139: 4136: 4133: 4130: 4127: 4125: 4122: 4121: 4117: 4114: 4111: 4108: 4105: 4102: 4099: 4096: 4093: 4091: 4088: 4087: 4083: 4080: 4077: 4075: 4072: 4069: 4066: 4063: 4060: 4057: 4055: 4052: 4051: 4047: 4044: 4041: 4039: 4035: 4032: 4029: 4026: 4023: 4020: 4017: 4015: 4012: 4011: 4007: 4004: 4001: 3999: 3995: 3991: 3988: 3985: 3982: 3979: 3976: 3973: 3971: 3968: 3967: 3963: 3960: 3957: 3955: 3952: 3949: 3946: 3943: 3940: 3937: 3935: 3932: 3931: 3927: 3924: 3921: 3919: 3915: 3912: 3909: 3906: 3903: 3900: 3897: 3895: 3892: 3891: 3887: 3884: 3881: 3877: 3875: 3871: 3868: 3865: 3862: 3859: 3856: 3853: 3851: 3848: 3847: 3843: 3840: 3837: 3834: 3831: 3828: 3825: 3822: 3819: 3817: 3814: 3813: 3805: 3802: 3799: 3796: 3793: 3790: 3783: 3776: 3773: 3770: 3769: 3762: 3759: 3745: 3742: 3741: 3737: 3734: 3733: 3729: 3726: 3725: 3721: 3718: 3717: 3713: 3710: 3709: 3705: 3702: 3701: 3697: 3694: 3693: 3689: 3686: 3685: 3681: 3679: 3678: 3675: 3674: 3665: 3662: 3659: 3656: 3653: 3651: 3648: 3645: 3642: 3639: 3636: 3633: 3630: 3627: 3624: 3621: 3619: 3616: 3615: 3611: 3608: 3605: 3602: 3599: 3597: 3594: 3591: 3588: 3585: 3582: 3579: 3576: 3573: 3570: 3567: 3565: 3562: 3561: 3557: 3554: 3551: 3548: 3545: 3543: 3540: 3537: 3534: 3531: 3528: 3525: 3522: 3519: 3516: 3513: 3511: 3508: 3507: 3503: 3500: 3497: 3494: 3491: 3489: 3486: 3483: 3480: 3477: 3474: 3471: 3468: 3465: 3462: 3459: 3457: 3454: 3453: 3449: 3446: 3443: 3440: 3437: 3434: 3431: 3428: 3425: 3422: 3419: 3416: 3413: 3410: 3407: 3404: 3402: 3399: 3398: 3394: 3391: 3388: 3385: 3382: 3380: 3377: 3374: 3371: 3368: 3365: 3362: 3359: 3356: 3353: 3350: 3348: 3345: 3344: 3340: 3337: 3334: 3331: 3328: 3326: 3323: 3320: 3317: 3314: 3311: 3308: 3305: 3302: 3299: 3296: 3294: 3291: 3290: 3286: 3283: 3280: 3277: 3274: 3272: 3269: 3266: 3263: 3260: 3257: 3254: 3251: 3248: 3245: 3242: 3240: 3237: 3236: 3232: 3229: 3226: 3223: 3220: 3218: 3215: 3212: 3209: 3206: 3203: 3200: 3197: 3194: 3191: 3188: 3186: 3183: 3182: 3178: 3175: 3172: 3169: 3166: 3164: 3161: 3158: 3155: 3152: 3149: 3146: 3143: 3140: 3137: 3134: 3132: 3129: 3128: 3124: 3121: 3118: 3115: 3112: 3110: 3107: 3104: 3101: 3098: 3095: 3092: 3089: 3086: 3083: 3080: 3078: 3075: 3074: 3070: 3067: 3064: 3061: 3058: 3056: 3053: 3050: 3047: 3044: 3041: 3038: 3035: 3032: 3029: 3026: 3024: 3021: 3020: 3016: 3013: 3010: 3008: 3005: 3003: 3000: 2998: 2995: 2992: 2990: 2987: 2985: 2982: 2979: 2977: 2975: 2972: 2971: 2967: 2964: 2962: 2960: 2958: 2955: 2952: 2949: 2946: 2943: 2940: 2937: 2934: 2931: 2928: 2925: 2923: 2922:Brexpiprazole 2920: 2919: 2915: 2912: 2909: 2906: 2903: 2901: 2898: 2895: 2892: 2889: 2886: 2883: 2880: 2877: 2874: 2871: 2869: 2866: 2865: 2861: 2858: 2855: 2852: 2849: 2847: 2844: 2841: 2838: 2835: 2832: 2829: 2826: 2823: 2820: 2817: 2815: 2812: 2811: 2807: 2804: 2801: 2798: 2795: 2793: 2790: 2787: 2784: 2781: 2778: 2775: 2772: 2769: 2766: 2763: 2761: 2758: 2757: 2753: 2750: 2747: 2744: 2741: 2739: 2736: 2733: 2730: 2727: 2724: 2721: 2718: 2715: 2712: 2709: 2707: 2704: 2703: 2700: 2694: 2692: 2686: 2684: 2678: 2676: 2670: 2668: 2662: 2660: 2654: 2652: 2646: 2644: 2638: 2636: 2630: 2628: 2622: 2620: 2614: 2612: 2606: 2604: 2598: 2596: 2590: 2588: 2582: 2580: 2574: 2571: 2570: 2567: 2566: 2564: 2554: 2552: 2548: 2544: 2535: 2523: 2521: 2517: 2501: 2494: 2479: 2468: 2464: 2460: 2456: 2452: 2445: 2438: 2434: 2426: 2418: 2417: 2410: 2409:Brexpiprazole 2406: 2357: 2353: 2345: 2343: 2339: 2335: 2327: 2311: 2307: 2279: 2271: 2269: 2254: 2250: 2247: 2232: 2229: 2224: 2219: 2214: 2211: 2206: 2201: 2196: 2194: 2191: 2190: 2186: 2183: 2178: 2173: 2170: 2165: 2160: 2155: 2150: 2148: 2145: 2144: 2140: 2137: 2132: 2127: 2124: 2119: 2116: 2111: 2106: 2104: 2101: 2100: 2096: 2092: 2088: 2084: 2080: 2076: 2073: 2068: 2063: 2058: 2053: 2048: 2043: 2038: 2036: 2033: 2032: 2028: 2024: 2021: 2018: 2013: 2010: 2007: 2004: 2001: 1996: 1994: 1991: 1990: 1986: 1982: 1978: 1973: 1968: 1963: 1958: 1955: 1950: 1945: 1940: 1938: 1935: 1934: 1931: 1927: 1923: 1920: 1917: 1912: 1907: 1902: 1897: 1894: 1891: 1889: 1886: 1885: 1882: 1878: 1874: 1870: 1866: 1863: 1858: 1853: 1848: 1843: 1838: 1835: 1830: 1828: 1825: 1824: 1820: 1816: 1813: 1808: 1803: 1798: 1793: 1788: 1783: 1778: 1773: 1771: 1768: 1767: 1764: 1760: 1756: 1753: 1750: 1745: 1736: 1727: 1724: 1719: 1714: 1709: 1707: 1704: 1703: 1699: 1695: 1690: 1685: 1682: 1677: 1674: 1669: 1666: 1663: 1661: 1658: 1657: 1653: 1649: 1646: 1641: 1636: 1631: 1628: 1623: 1618: 1613: 1611: 1608: 1607: 1603: 1599: 1595: 1591: 1587: 1583: 1579: 1575: 1571: 1566: 1561: 1556: 1551: 1546: 1541: 1536: 1531: 1529: 1526: 1525: 1522: 1517: 1512: 1509: 1504: 1499: 1494: 1491: 1486: 1484: 1481: 1480: 1476: 1473: 1470: 1465: 1460: 1455: 1450: 1445: 1440: 1435: 1433: 1430: 1429: 1425: 1421: 1417: 1413: 1409: 1405: 1401: 1397: 1394: 1391: 1386: 1381: 1376: 1371: 1366: 1361: 1359: 1356: 1355: 1352: 1348: 1345: 1342: 1337: 1334: 1331: 1326: 1321: 1316: 1311: 1309: 1306: 1305: 1301: 1298: 1295: 1292: 1289: 1287: 1283: 1280: 1277: 1275: 1270: 1268: 1265: 1263: 1260: 1257: 1254: 1253: 1246: 1238: 1236: 1231: 1229: 1225: 1221: 1217: 1213: 1207: 1205: 1201: 1197: 1193: 1187: 1185: 1177: 1169: 1160: 1154: 1147: 1138: 1131: 1124: 1120: 1115: 1111: 1110:hyperglycemia 1107: 1097: 1094: 1092: 1088: 1078: 1075: 1073: 1067: 1057: 1054: 1048: 1046: 1040: 1036: 1033: 1015: 1012: 1009: 1006: 1005: 1004: 1003: 998: 994: 991: 988: 985: 982: 980: 977: 976: 972: 969: 966: 963: 960: 958: 955: 954: 950: 947: 944: 941: 938: 936: 933: 932: 928: 925: 922: 919: 916: 914: 911: 910: 906: 903: 900: 897: 894: 892: 889: 888: 884: 881: 878: 875: 872: 870: 867: 866: 862: 859: 856: 853: 850: 848: 845: 844: 840: 837: 834: 831: 828: 826: 823: 822: 818: 815: 812: 809: 806: 804: 801: 800: 796: 793: 790: 787: 784: 782: 779: 778: 774: 771: 768: 765: 762: 760: 757: 756: 752: 749: 746: 743: 740: 738: 735: 734: 730: 727: 724: 721: 718: 716: 713: 712: 708: 705: 702: 699: 696: 694: 691: 690: 686: 683: 680: 677: 674: 672: 669: 668: 664: 661: 658: 655: 652: 650: 647: 646: 642: 639: 636: 633: 630: 628: 625: 624: 620: 617: 614: 611: 609:Schizophrenia 608: 605: 604: 597: 589: 587: 586:brexpiprazole 582: 578: 568: 566: 562: 552: 550: 546: 542: 538: 534: 530: 526: 522: 518: 517:brexpiprazole 514: 510: 508: 507:non-psychotic 504: 500: 493: 490: 488: 485: 483: 480: 478: 475: 473: 472:Brexpiprazole 470: 468: 465: 464: 463: 461: 458: 457:non-psychotic 448: 446: 442: 438: 434: 430: 426: 422: 411: 408: 404: 397: 394: 390: 388: 387: 383:published in 382: 378: 374: 370: 366: 365:triglycerides 362: 358: 354: 349: 345: 340: 335: 324: 322: 318: 314: 309: 304: 301: 298: 290:Schizophrenia 287: 285: 284:off-label use 281: 277: 273: 269: 265: 261: 257: 253: 252:schizophrenia 243: 241: 237: 233: 229: 225: 221: 217: 211: 209: 205: 201: 197: 193: 190: 189:motor control 187: 183: 179: 175: 170: 168: 164: 160: 156: 152: 151:schizophrenia 148: 144: 140: 136: 132: 128: 124: 123: 118: 114: 113:tranquilizers 110: 109:antipsychotic 106: 102: 100: 95: 91: 87: 83: 74: 70: 65: 61: 59: 55: 50: 46: 41: 36: 33: 32: 27: 22: 19: 20071: 20062: 20049: 20040: 20031: 20022: 20011: 20010: 19966: 19954:Vortioxetine 19940:fluphenazine 19914:clomipramine 19809:JNJ-18038683 19799:methysergide 19710:fluperlapine 19690:aripiprazole 19681: 19679:Antagonists: 19678: 19643:frovatriptan 19575: 19516: 19481:clomipramine 19389:Landipirdine 19379:Idalopirdine 19364:Cerlapirdine 19311:fluperlapine 19295:aripiprazole 19290: 19283:Antagonists: 19282: 19191:methysergide 19155: 19116:methysergide 19104: 19075:Antagonists: 19074: 19025: 18959:Antagonists: 18958: 18901:Prucalopride 18847: 18805: 18783:Vortioxetine 18697:Palonosetron 18608: 18586:Antagonists: 18585: 18463: 18395: 18377:thioridazine 18213:Medifoxamine 18168:methysergide 18120:Deramciclane 18074:paliperidone 18058:fluperlapine 18041: 18029:Antagonists: 18028: 17908:aripiprazole 17791:ergine (LSA) 17634: 17597: 17502:Sarpogrelate 17352:aripiprazole 17343: 17336:Antagonists: 17335: 17212:methysergide 17147:fenfluramine 17131:Amphetamines 17117: 17076: 17054:Volinanserin 17040:thioridazine 17012:perphenazine 17000:fluphenazine 16942:Teniloxazine 16893:Sarpogrelate 16883:Roluperidone 16853:Pimavanserin 16833:Nelotanserin 16808:Medifoxamine 16793:Landipirdine 16753:methysergide 16724:Eplivanserin 16714:Deramciclane 16669:paliperidone 16637:fluperlapine 16625:clocapramine 16621:carpipramine 16605:aripiprazole 16596: 16550:5-MeO-NBpBrT 16542:Antagonists: 16541: 16314:ergine (LSA) 16136:2CBFly-NBOMe 16095: 16043:Antagonists: 16042: 15986:methysergide 15957: 15913: 15898:Antagonists: 15897: 15859:methysergide 15846: 15796: 15701:Antagonists: 15700: 15657:zolmitriptan 15641:frovatriptan 15575:methysergide 15532: 15487: 15383:Antagonists: 15382: 15370:Vortioxetine 15337:zolmitriptan 15292:methysergide 15233: 15186: 15154:Spiroxatrine 14975: 14973:Antagonists: 14972: 14723:methysergide 14640:tandospirone 14586:aripiprazole 14581: 14576:vortioxetine 14529: 14446: 14437: 14428: 14419: 14410: 14401: 14390: 14389: 14342:Stepholidine 14337:Spiroxatrine 14327:Seridopidine 14322:SB-277,011-A 14242:Fenfluramine 14202:Bromerguride 14182: 14176:Trimipramine 14171:Propiomazine 14151: 14130:Promethazine 14125:Metopimazine 14055: 13974:Paliperidone 13919:Fluperlapine 13909:Elopiprazole 13874:Clocapramine 13864:Carpipramine 13839: 13793:Thioridazine 13753:Prothipendyl 13713:Perphenazine 13673:Mesoridazine 13648:Homopipramol 13638:Fluspirilene 13628:Fluphenazine 13583:Clothixamide 13578:Clopenthixol 13553:Chloracizine 13548:Butaperazine 13518:Acepromazine 13513: 13473:Salvinorin A 13283: 13277:Norclozapine 13272:Lumateperone 13232:Aripiprazole 13222: 13162: 13131: 13085:Chanoclavine 13070: 13039: 13018: 12951: 12915:Paliperidone 12895:Norclozapine 12885:Fluperlapine 12855: 12829:Thioridazine 12814:Perphenazine 12804:Fluphenazine 12774: 12744: 12719:Stepholidine 12664: 12599: 12558: 12517: 12467:Benzazepines 12466: 12354: 12331: 12311:Pimavanserin 12302: 12285:+samidorphan 12264: 12236:Aripiprazole 12231:quinolinones 12225: 12219:Lumateperone 12212: 12184:Paliperidone 12163: 12155: 12142: 12111:Clocapramine 12106:Carpipramine 12099: 12086: 12038: 11982:Clopenthixol 11970: 11954:Thioridazine 11885:Perphenazine 11870:Mesoridazine 11848:Fluphenazine 11823:Butaperazine 11813:Acepromazine 11806: 11790:Fluspirilene 11783: 11716: 11634:. Retrieved 11630:the original 11600: 11596: 11586:December 14, 11584:. Retrieved 11577:the original 11556: 11552: 11523:. Retrieved 11518: 11509: 11497:. Retrieved 11493: 11484: 11472:. Retrieved 11468:the original 11463: 11454: 11441:. Retrieved 11437:the original 11432: 11408:. Retrieved 11404:the original 11399: 11390: 11378:. Retrieved 11373: 11364: 11332:(1): 45835. 11329: 11325: 11315: 11288: 11284: 11274: 11244:(1): 13–24. 11241: 11237: 11231: 11196: 11192: 11182: 11173: 11169: 11163: 11138: 11134: 11128: 11106:(1): 31–49. 11103: 11099: 11093: 11076: 11072: 11065: 11056: 11050: 11015: 11011: 10981: 10977: 10971: 10962: 10928: 10924: 10906: 10902: 10896: 10874:(1): 117–9. 10871: 10867: 10861: 10852: 10822:(2): 173–6. 10819: 10815: 10809: 10800: 10770:(1): 65–84. 10767: 10763: 10757: 10747:November 27, 10745:. Retrieved 10732: 10722:November 27, 10720:. Retrieved 10707: 10697:November 27, 10695:. Retrieved 10689: 10680: 10671: 10659:. Retrieved 10655:the original 10650: 10637: 10612: 10608: 10602: 10569: 10565: 10556: 10529: 10525: 10515: 10482: 10478: 10472: 10447: 10443: 10437: 10425:. Retrieved 10420: 10408: 10388: 10381: 10369:. Retrieved 10354: 10347: 10335:. Retrieved 10320: 10313: 10301:. Retrieved 10297:the original 10286: 10253: 10249: 10242: 10230:. Retrieved 10226: 10181:(1): 65–73. 10178: 10174: 10168: 10143: 10139: 10133: 10121:. Retrieved 10106: 10099: 10087:. Retrieved 10083: 10074: 10062:. Retrieved 10058: 10049: 10037:. Retrieved 10032: 10023: 10011:. Retrieved 10007:the original 10002: 9993: 9981:. Retrieved 9976: 9967: 9955:. Retrieved 9951:the original 9946: 9937: 9925:. Retrieved 9910: 9903: 9891:. Retrieved 9886: 9877: 9852: 9848: 9842: 9809: 9805: 9799: 9787:. Retrieved 9772: 9765: 9754:the original 9745: 9707: 9700: 9680: 9673: 9640: 9636: 9630: 9610: 9586: 9572: 9566: 9554:. Retrieved 9549: 9540: 9507: 9503: 9497: 9464: 9460: 9413:(3): 153–9. 9410: 9406: 9381:. Retrieved 9376: 9219:11343/251495 9199: 9195: 9185: 9152: 9148: 9141: 9114: 9110: 9100: 9063: 9059: 9049: 8999:(1): 64–77. 8996: 8992: 8982: 8939: 8935: 8925: 8892: 8888: 8881: 8872: 8866: 8839: 8835: 8791:(2): 151–6. 8788: 8784: 8751:(1): 27–38. 8748: 8744: 8681:(1): 88–95. 8678: 8674: 8664: 8623: 8619: 8613: 8568: 8564: 8554: 8519: 8515: 8505: 8473:(9): 900–6. 8470: 8466: 8456: 8432:(1): 44–51. 8429: 8425: 8415: 8380: 8376: 8366: 8338: 8278:(1): 58–62. 8275: 8271: 8261: 8226: 8222: 8191:. Retrieved 8186: 8176: 8143: 8139: 8133: 8096: 8092: 8082: 8049: 8045: 7991: 7987: 7977: 7944: 7940: 7933: 7909:(11): 14–7. 7906: 7902: 7865:(7): 28–31. 7862: 7858: 7829:. Retrieved 7825: 7816: 7804:. Retrieved 7800: 7791: 7758: 7754: 7712: 7708: 7701: 7652: 7648: 7638: 7603: 7599: 7589: 7577:. Retrieved 7573: 7563: 7536: 7532: 7522: 7485: 7481: 7443: 7422:. Retrieved 7417: 7407: 7395:. Retrieved 7390: 7380: 7371: 7348:. Retrieved 7344: 7335: 7311: 7304: 7271: 7267: 7260: 7241: 7237: 7227: 7202: 7198: 7192: 7162:(2): 133–9. 7159: 7155: 7149: 7124: 7120: 7113: 7086: 7082: 7072: 7037: 7033: 7023: 6988: 6984: 6974: 6931: 6927: 6913: 6870: 6866: 6856: 6829: 6825: 6815: 6801:(4): 338–9. 6798: 6794: 6788: 6771: 6767: 6761: 6726: 6722: 6712: 6679: 6675: 6669: 6642: 6638: 6628: 6596:(4): 892–9. 6593: 6589: 6579: 6546: 6542: 6529: 6519:November 25, 6517:. Retrieved 6512: 6500: 6486:cite journal 6451: 6447: 6437: 6418: 6412: 6385: 6381: 6371: 6359:. Retrieved 6355: 6346: 6313: 6309: 6303: 6268: 6264: 6255: 6222: 6218: 6173: 6169: 6129: 6123: 6098: 6094: 6088: 6015: 6013: 6003: 5993: 5784:Pimavanserin 5734:Paliperidone 5559:Clocapramine 5534:Carpipramine 5459:Aripiprazole 5368:Generic name 5345: 5341: 5325: 5321: 5306: 5302:paliperidone 5298:aripiprazole 5266: 5253: 5250: 5212: 5204: 5117:21 days 5110:Microspheres 4977:27 days 4870:30 days 4775:Fluspirilene 4690:17 days 4653:19 days 4420: 4419: 4164:Paliperidone 3850:Aripiprazole 3777:Half-life (t 3756: 3672: 3671: 3293:Paliperidone 2760:Aripiprazole 2572:Generic Name 2562: 2561: 2560: 2541: 2524: 2520:aripiprazole 2467:aripiprazole 2419: 2407: 2346: 2338:galactorrhea 2272: 2265: 2257:Pharmacology 2251: 2243: 2095:gynecomastia 1827:Paliperidone 1586:eosinophilia 1410:(<0.1%), 1408:pancreatitis 1358:Aripiprazole 1293:prolongation 1255:Generic Name 1235:risk factors 1232: 1208: 1192:Aripiprazole 1188: 1168:adrenoceptor 1161: 1103: 1095: 1084: 1076: 1069: 1049: 1041: 1037: 1028: 1001: 1000: 847:Paliperidone 649:Aripiprazole 574: 565:aripiprazole 558: 545:lumateperone 513:Aripiprazole 511: 506: 502: 496: 467:Aripiprazole 456: 454: 418: 403:aripiprazole 399: 395: 391: 384: 380: 344:perphenazine 330: 321:aripiprazole 305: 302: 293: 249: 246:Medical uses 212: 192:disabilities 171: 161:, and as an 120: 117:neuroleptics 104: 97: 93: 89: 85: 81: 79: 67:Legal status 29: 18: 20024:Adrenergics 19984:Piperazines 19900:mirtazapine 19892:maprotiline 19803:sergolexole 19795:metergoline 19791:mesulergine 19771:cabergoline 19750:EGIS-12,233 19730:ziprasidone 19718:risperidone 19702:clorotepine 19686:amisulpride 19649:Tryptamines 19542:Piperazines 19399:Masupirdine 19369:EGIS-12,233 19315:iloperidone 19303:clorotepine 19207:Tryptamines 19187:metergoline 19183:mesulergine 19122:Piperazines 19112:metergoline 19052:Tryptamines 18936:Usmarapride 18891:Minesapride 18866:Cinitapride 18814:Piperazines 18773:sevoflurane 18750:Tropisetron 18745:Tropanserin 18734:mirtazapine 18692:Ondansetron 18672:Granisetron 18647:Cilansetron 18632:Batanopride 18599:Arazasetron 18594:Anpirtoline 18533:Tryptamines 18495:Piperazines 18373:pipamperone 18322:mirtazapine 18314:maprotiline 18288:SDZ SER-082 18238:Propranolol 18228:Pirenperone 18178:Etoperidone 18172:sergolexole 18164:metergoline 18160:mesulergine 18135:Eltoprazine 18090:ziprasidone 18082:risperidone 18062:iloperidone 18050:clorotepine 18037:Agomelatine 18032:Adatanserin 18001:Vabicaserin 17955:Tryptamines 17904:Piperazines 17783:cabergoline 17559:mirtazapine 17537:SDZ SER-082 17487:Rauwolscine 17477:Propranolol 17467:Pirenperone 17436:mesulergine 17396:ziprasidone 17392:risperidone 17384:pipamperone 17364:cariprazine 17348:amisulpride 17339:Agomelatine 17274:Tryptamines 17249:Piperazines 17192:cabergoline 17088:nicergoline 17044:thiothixene 17020:pipamperone 17004:haloperidol 16976:mirtazapine 16968:maprotiline 16914:mepiprazole 16902:etoperidone 16873:Rauwolscine 16868:Pruvanserin 16858:Pirenperone 16773:Glemanserin 16768:Flibanserin 16757:sergolexole 16749:metergoline 16745:mesulergine 16689:ziprasidone 16685:zicronapine 16677:risperidone 16661:ocaperidone 16657:mosapramine 16645:iloperidone 16641:gevotroline 16629:clorotepine 16613:blonanserin 16578:hydroxyzine 16560:Adatanserin 16488:Tryptamines 16455:Piperazines 16310:cabergoline 16128:2CBCB-NBOMe 16124:25TFM-NBOMe 16025:Tryptamines 16019:sumatriptan 16015:naratriptan 15880:Tryptamines 15800:Acetryptine 15784:Ziprasidone 15723:metergoline 15663:Tryptamines 15653:sumatriptan 15649:rizatriptan 15645:naratriptan 15633:donitriptan 15625:almotriptan 15559:cabergoline 15495:cabergoline 15434:metergoline 15415:propranolol 15348:Tryptamines 15333:sumatriptan 15325:donitriptan 15267:Eltoprazine 15237:Anpirtoline 15190:Acetryptine 15139:SDZ 216-525 15079:Flopropione 15068:metergoline 15039:propranolol 14984:risperidone 14980:iloperidone 14893:Tryptamines 14838:Rauwolscine 14828:Pardoprunox 14768:Flibanserin 14699:cabergoline 14686:Enciprazine 14681:Eltoprazine 14661:Cannabidiol 14636:perospirone 14614:ziprasidone 14598:cariprazine 14552:etoperidone 14543:Amphetamine 14538:Adatanserin 14403:Adrenergics 14307:Pridopidine 14292:Nafadotride 14277:Metergoline 14192:Alpiropride 14140:Trazpiroben 14110:Hydroxyzine 14105:Eticlopride 14100:Domperidone 14070:Alimemazine 14044:Ziprasidone 14039:Zicronapine 14034:Veralipride 14019:Tefludazine 14009:Risperidone 14004:Remoxipride 13989:Pipotiazine 13979:Perospirone 13968:+fluoxetine 13959:Ocaperidone 13954:Mosapramine 13939:Mazapertine 13929:Iloperidone 13924:Gevotroline 13914:Flumezapine 13894:Cyamemazine 13879:Clorotepine 13859:Blonanserin 13844:Amisulpride 13798:Thiothixene 13733:Pipamperone 13698:Perathiepin 13693:Penfluridol 13688:Nemonapride 13643:Haloperidol 13622:+melitracen 13588:Clopimozide 13538:Bromperidol 13507:Antagonists 13498:WAY-100,635 13443:Quinelorane 13438:Quinagolide 13418:Pramipexole 13383:Pardoprunox 13368:Mesulergine 13358:Flibanserin 13348:Dizocilpine 13328:Armodafinil 13318:Apomorphine 13262:Cariprazine 13236:+sertraline 13177:Etilevodopa 13100:Ergocornine 13095:Epicriptine 13080:Cabergoline 13033:Rimantadine 13019:Adamantanes 12940:Ziprasidone 12935:Zicronapine 12930:Tefludazine 12925:Risperidone 12909:+fluoxetine 12890:Iloperidone 12865:Clorotepine 12834:Thiothixene 12824:Pifluthixol 12798:+melitracen 12768:Antagonists 12674:Apomorphine 12619:Etilevodopa 12593:Doxanthrine 12583:Dinapsoline 12522:Cabergoline 12379:from market 12358:Azacyclonol 12306:Blonanserin 12258:Cariprazine 12206:Ziprasidone 12201:Risperidone 12196:Perospirone 12174:Iloperidone 12131:Mosapramine 12116:Clorotepine 12080:Veralipride 12060:Remoxipride 12055:Nemonapride 12045:Amisulpride 11994:Flupentixol 11912:Pipotiazine 11880:Periciazine 11838:Cyamemazine 11795:Penfluridol 11762:Pipamperone 11745:Haloperidol 11728:Bromperidol 11525:February 2, 11499:February 2, 11474:February 2, 11443:February 2, 11410:February 2, 11380:February 1, 10661:October 10, 10572:(1): 43–9. 10084:Rexulti.com 9643:(1): 3–13. 9504:Drug Safety 8229:(1): 6–14. 8193:October 10, 7831:January 11, 7806:October 18, 7579:October 18, 7574:www.fda.gov 7424:October 10, 7397:October 10, 7350:October 14, 6061:p. 355-360. 6045:p. 346-352. 6031:p. 329-336. 5934:Ziprasidone 5859:Risperidone 5834:Remoxipride 5759:Perospirone 5684:Mosapramine 5609:Iloperidone 5509:Blonanserin 5434:Amisulpride 5294:ziprasidone 5286:risperidone 5099:Risperidone 4864:7 days 4798:7 days 4761:4 days 4687:8 days 4573:7 days 4402:Urine (17%) 4346:Ziprasidone 4274:Risperidone 4204:Perospirone 4014:Iloperidone 3934:Blonanserin 3816:Amisulpride 3564:Ziprasidone 3401:Risperidone 3077:Iloperidone 2974:Cariprazine 2868:Blonanserin 2706:Amisulpride 2543:Inhibition. 2516:cariprazine 2463:risperidone 2437:ziprasidone 2193:Ziprasidone 2035:Risperidone 1993:Remoxipride 1888:Perospirone 1759:neutropenia 1610:Iloperidone 1598:myocarditis 1483:Blonanserin 1420:neutropenia 1308:Amisulpride 1286:Orthostasis 1282:Hypotension 1258:Weight gain 1200:ziprazidone 957:Ziprasidone 913:Risperidone 869:Perospirone 759:Iloperidone 715:Cariprazine 693:Blonanserin 627:Amisulpride 561:risperidone 533:Cariprazine 521:cariprazine 492:Ziprasidone 477:Cariprazine 421:acute mania 377:ziprasidone 369:risperidone 361:cholesterol 232:blood clots 178:haloperidol 73:In Wikidata 20090:Categories 19918:imipramine 19879:SSR-181507 19854:SB-656104A 19829:Ritanserin 19819:LY-215,840 19814:Ketanserin 19787:LY-215,840 19779:ergotamine 19763:amesergide 19740:Butaclamol 19726:tiospirone 19722:sertindole 19714:olanzapine 19589:Bifeprunox 19532:lergotrile 19429:Ro 63-0563 19424:Ro 04-6790 19419:Ritanserin 19384:Ketanserin 19323:tiospirone 19319:olanzapine 19270:WAY-208466 19265:WAY-181187 19259:tryptamine 19239:EMD-386088 19171:ergotamine 19093:Ritanserin 19037:ergotamine 18941:Velusetrag 18911:Renzapride 18793:Zatosetron 18712:Ricasetron 18707:Renzapride 18702:Ramosetron 18682:Lerisetron 18662:Dolasetron 18621:quetiapine 18617:olanzapine 18559:isoflurane 18383:Xylamidine 18306:aptazapine 18243:Ritanserin 18223:Nefazodone 18198:Ketanserin 18193:Irindalone 18183:Fluoxetine 18156:LY-215,840 18144:amesergide 18130:Dotarizine 18110:Cinanserin 18100:Captodiame 18086:sertindole 18078:quetiapine 18070:olanzapine 18011:WAY-161503 17995:tryptamine 17991:psilocybin 17935:PNU-181731 17894:lophophine 17880:Oxaflozane 17838:Lorcaserin 17833:Flumexadol 17795:ergotamine 17676:5-MeO-DiPT 17492:Ritanserin 17457:Metadoxine 17442:Ketanserin 17416:amesergide 17388:quetiapine 17380:olanzapine 17322:tryptamine 17318:psilocybin 17222:Lorcaserin 17204:ergotamine 17059:Xylamidine 17028:setoperone 16960:aptazapine 16947:Temanogrel 16918:nefazodone 16910:lubazodone 16878:Ritanserin 16843:Pelanserin 16783:Ketanserin 16778:Irindalone 16763:Fananserin 16741:LY-215,840 16733:amesergide 16719:Dotarizine 16704:Cinanserin 16681:sertindole 16673:quetiapine 16665:olanzapine 16649:lurasidone 16601:amperozide 16565:Altanserin 16545:5-I-R91150 16528:tryptamine 16524:psilocybin 16445:lophophine 16426:PNU-181731 16411:Oxaflozane 16379:Lorcaserin 16374:Jimscaline 16364:Flumexadol 16322:ergotamine 16190:5-MeO-DiPT 16011:eletriptan 15992:Lasmiditan 15966:CP-122,288 15884:tryptamine 15874:eletriptan 15774:Ritanserin 15734:Ketanserin 15709:BRL-15,572 15637:eletriptan 15629:avitriptan 15606:PNU-142633 15601:PNU-109291 15567:ergotamine 15536:CP-122,288 15445:Isamoltane 15419:tertatolol 15411:penbutolol 15407:oxprenolol 15403:isamoltane 15395:alprenolol 15386:AR-A000002 15329:eletriptan 15321:avitriptan 15284:ergotamine 15257:CP-122,288 15242:CGS-12066A 15195:Carvedilol 15174:Xylamidine 15169:WAY-100635 15164:WAY-100135 15134:SB-649,915 15124:Robalzotan 15089:Isamoltane 15059:Dotarizine 15043:tertatolol 15027:penbutolol 15023:oxprenolol 15019:isamoltane 15003:alprenolol 14988:sertindole 14955:Xaliproden 14950:Vilazodone 14940:U-92,016-A 14929:psilocybin 14917:indorenate 14888:Sunepitron 14883:SSR-181507 14833:Piclozotan 14823:Oxaflozane 14818:Osemozotan 14783:Lesopitron 14773:Flumexadol 14763:Flesinoxan 14707:ergotamine 14646:Bay R 1531 14628:eptapirone 14620:Azapirones 14610:quetiapine 14606:lurasidone 14572:vilazodone 14560:nefazodone 14495:modulators 14312:Raclopride 14302:PNU-99,194 14297:Nuciferine 14237:Fananserin 14232:Fallypride 14161:Nefazodone 14090:Clebopride 14085:Bromopride 14075:Alizapride 14029:Tiospirone 14024:Tenilapine 14014:Sertindole 13999:Quetiapine 13994:Piquindone 13964:Olanzapine 13934:Lurasidone 13904:Dixyrazine 13869:Cinuperone 13828:Zetidoline 13803:Timiperone 13778:Teflutixol 13773:Sultopride 13613:Fluotracen 13608:Flucindole 13603:Fluanisone 13598:Fluacizine 13593:Droperidol 13573:Ciclindole 13543:Butaclamol 13533:Benperidol 13493:Umespirone 13488:Talipexole 13483:Sumanirole 13478:SKF-83,959 13463:Ropinirole 13448:Quinpirole 13403:PF-592,379 13398:PF-219,061 13393:PD-168,077 13388:PD-128,907 13353:Esketamine 13343:CP-226,269 13338:Captodiame 13323:Arketamine 13247:Bifeprunox 13211:Melevodopa 13172:Dopexamine 13151:Dinoxyline 13105:Lergotrile 13059:Rotigotine 13023:Amantadine 12920:Quetiapine 12905:Olanzapine 12870:Clotiapine 12779:Butaclamol 12714:SKF-89,626 12709:SKF-89,145 12704:Rotigotine 12694:PF 6669571 12689:PF-6649751 12684:Nuciferine 12637:Melevodopa 12614:Dopexamine 12588:Dinoxyline 12527:CY-208,243 12511:Zelandopam 12501:SKF-83,959 12496:SKF-82,958 12491:SKF-81,297 12486:SKF-77,434 12481:SKF-38,393 12476:Fenoldopam 12440:modulators 12338:Oxypertine 12316:Sertindole 12291:Quetiapine 12281:Olanzapine 12266:Tricyclics 12179:Lurasidone 12121:Clotiapine 12101:Tricyclics 12070:Sultopride 12040:Benzamides 11843:Dixyrazine 11772:Timiperone 11740:Droperidol 11723:Benperidol 11636:August 18, 10003:Invega.com 9977:RxWiki.com 8358:1301978997 7994:: 483–90. 7903:Psychiatry 7859:Psychiatry 6081:References 5884:Sertindole 5809:Quetiapine 5709:Olanzapine 5634:Lurasidone 5290:quetiapine 5282:olanzapine 5213:Footnotes: 5075:Sesame oil 5001:Sesame oil 4964:Sesame oil 4825:Sesame oil 4751:Sesame oil 4714:Sesame oil 4603:Sesame oil 4479:Brand name 4476:Medication 4317:72 (55-90) 4310:Sertindole 4238:Quetiapine 4124:Olanzapine 4054:Lurasidone 3958:84% (Oral) 3898:Sublingual 3722:Very High 3456:Sertindole 3347:Quetiapine 3239:Olanzapine 3131:Lurasidone 2983:+++++ (PA) 2938:+++++ (PA) 2929:+++++ (PA) 2459:lurasidone 2342:amenorrhea 2103:Sertindole 1937:Quetiapine 1928:elevation 1770:Olanzapine 1763:leukopenia 1698:creatinine 1660:Lurasidone 1424:angioedema 1416:leukopenia 1414:(<1%), 1228:nizatidine 1216:zonisamide 1212:topiramate 1204:lurasidone 1100:Metabolism 935:Sertindole 891:Quetiapine 825:Olanzapine 781:Lurasidone 541:lurasidone 537:Quetiapine 529:quetiapine 525:olanzapine 487:Quetiapine 482:Olanzapine 445:Lurasidone 441:olanzapine 437:quetiapine 386:The Lancet 373:quetiapine 348:olanzapine 31:Drug class 20012:See also: 19978:pergolide 19970:Ergolines 19896:mianserin 19888:amoxapine 19874:Spiperone 19859:SB-691673 19849:SB-656104 19844:SB-269970 19839:SB-258741 19834:SB-258719 19755:Ergolines 19706:clozapine 19694:asenapine 19665:N-Me-5-HT 19661:bufotenin 19629:Sarizotan 19624:RU-24,969 19599:Ergolines 19579:8-OH-DPAT 19576:Agonists: 19536:pergolide 19520:Ergolines 19467:mianserin 19463:amoxapine 19454:SB-742457 19449:SB-399885 19444:SB-357134 19439:SB-271046 19434:SB-258585 19414:PRX-07034 19374:GW-742457 19359:BVT-74316 19349:BGC20-760 19307:clozapine 19299:asenapine 19251:N-Me-5-HT 19247:LY-586713 19227:Bufotenin 19211:2-Me-5-HT 19159:Ergolines 19156:Agonists: 19108:Ergolines 19098:SB-699551 19078:Asenapine 19029:Ergolines 19026:Agonists: 18997:SB-204070 18992:SB-203186 18977:Piboserod 18967:GR-125487 18962:GR-113808 18946:Zacopride 18931:Tegaserod 18921:RS-67,506 18916:RS-67,333 18906:PRX-03140 18896:Mosapride 18881:Dazopride 18876:CJ-033466 18871:Cisapride 18861:Capeserod 18848:Agonists: 18788:Zacopride 18730:mianserin 18726:amoxapine 18687:Memantine 18657:Dazopride 18642:Bupropion 18627:Azasetron 18613:clozapine 18589:Alosetron 18555:halothane 18537:2-Me-5-HT 18528:SR-57227A 18507:quipazine 18464:Agonists: 18404:Ergolines 18399:Efavirenz 18338:Trazodone 18318:mianserin 18302:amoxapine 18283:SB-243213 18278:SB-242084 18273:SB-228357 18268:SB-221284 18263:SB-206553 18258:SB-200646 18248:RS-102221 18233:Pizotifen 18203:Ketotifen 18188:FR-260010 18140:Ergolines 18066:melperone 18054:clozapine 18046:asenapine 17967:bufotenin 17945:Ro60-0213 17940:Ro60-0175 17930:PNU-22394 17920:quipazine 17898:mescaline 17885:PHA-57378 17875:ORG-37684 17870:ORG-12962 17827:pergolide 17775:Ergolines 17748:Dimemebfe 17743:CP-809101 17738:Alstonine 17733:AL-38022A 17714:α-Me-5-HT 17710:5-MeO-αMT 17706:5-MeO-αET 17684:5-MeO-DPT 17680:5-MeO-DMT 17672:5-MeO-DET 17635:Agonists: 17601:Ergolines 17585:Yohimbine 17565:Trazodone 17555:mianserin 17551:amoxapine 17542:Tegaserod 17532:SB-228357 17527:SB-221284 17522:SB-215505 17517:SB-206553 17512:SB-204741 17507:SB-200646 17497:RS-127445 17482:PRX-08066 17472:Pizotifen 17447:LY-393558 17432:LY-272015 17412:Ergolines 17407:EGIS-7625 17368:clozapine 17356:asenapine 17294:bufotenin 17290:α-Me-5-HT 17264:Ro60-0175 17259:PNU-22394 17216:pergolide 17188:Ergolines 17161:BW-723C86 17118:Agonists: 17080:Ergolines 17064:Yohimbine 17036:spiramide 17032:spiperone 16972:mianserin 16956:amoxapine 16932:SR-46349B 16926:trazodone 16863:Pizotifen 16828:Nantenine 16798:LY-393558 16729:Ergolines 16653:melperone 16633:clozapine 16609:asenapine 16586:perlapine 16582:ketotifen 16500:bufotenin 16463:quipazine 16449:mescaline 16421:PNU-22394 16416:PHA-57378 16369:IHCH-7113 16358:pergolide 16294:Ergolines 16289:Efavirenz 16257:Dimemebfe 16247:AL-37350A 16228:α-Me-5-HT 16224:5-MeO-αMT 16220:5-MeO-αET 16198:5-MeO-DPT 16194:5-MeO-DMT 16186:5-MeO-DET 16132:25CN-NBOH 16120:25C-NBOMe 16116:25B-NBOMe 16112:25I-NBOMe 16096:Agonists: 16051:Mianserin 15997:LY-334370 15971:Ergolines 15961:BRL-54443 15958:Agonists: 15917:Ergolines 15855:Ergolines 15850:BRL-54443 15847:Agonists: 15817:pergolide 15805:Ergolines 15779:Yohimbine 15769:Mianserin 15759:LY-456220 15754:LY-456219 15749:LY-393558 15744:LY-367642 15739:LY-310762 15729:GR-127935 15719:Ergolines 15714:Elzasonan 15704:Alniditan 15551:Ergolines 15546:CP-286601 15541:CP-135807 15533:Agonists: 15491:Ergolines 15475:Yohimbine 15470:SB-236057 15465:SB-224289 15460:SB-216641 15450:LY-393558 15440:GR-127935 15430:Ergolines 15425:Elzasonan 15399:carteolol 15307:RU-24,969 15296:pergolide 15272:Ergolines 15262:CP-135807 15234:Agonists: 15200:Ergolines 15149:Spiramide 15144:Spiperone 15094:Lecozotan 15074:FCE-24379 15064:Ergolines 15049:BMY-7,378 15031:pindobind 15007:carteolol 14960:Yohimbine 14921:N-Me-5-HT 14909:bufotenin 14901:5-MeO-DMT 14873:Sarizotan 14853:RU-24,969 14848:Roxindole 14843:Repinotan 14808:Naluzotan 14793:LY-301317 14788:LY-293284 14727:pergolide 14691:Ergolines 14676:Ebalzotan 14666:Dimemebfe 14656:BMY-14802 14651:Befiradol 14624:buspirone 14602:clozapine 14590:asenapine 14564:trazodone 14533:8-OH-DPAT 14530:Agonists: 14391:See also: 14372:Yohimbine 14352:Terguride 14317:Sarizotan 14262:L-745,870 14257:L-741,626 14212:Buspirone 14166:Opipramol 14156:Amoxapine 13949:Molindone 13944:Melperone 13889:Clozapine 13849:Asenapine 13768:Sulpiride 13748:Promazine 13738:Preclamol 13653:Lenperone 13528:Azaperone 13468:Roxindole 13458:Ro10-5824 13433:Pukateine 13423:Preclamol 13413:Piribedil 13373:Modafinil 13313:Aplindore 13308:Adrafinil 13206:-Tyrosine 13182:Ibopamine 13125:Terguride 13120:Pergolide 13071:Ergolines 13054:8-OH-PBZI 13049:7-OH-DPAT 13044:5-OH-DPAT 13028:Memantine 12986:SCH-23390 12981:Perlapine 12956:Berupipam 12875:Clozapine 12860:Asenapine 12759:Mevidalen 12724:Tavapadon 12653:-Tyrosine 12624:Ibopamine 12552:Terguride 12547:Pergolide 12518:Ergolines 12389:Phase III 12377:Withdrawn 12343:Reserpine 12276:Clozapine 12271:Asenapine 12146:Molindone 12093:Melperone 12065:Sulpiride 11934:Promazine 11767:Spiperone 11348:2155-7780 10931:: 41–54. 10909:(1): 1–6. 10764:CNS Drugs 10615:: 180–6. 10203:206489515 9743:Stahl S. 9489:262520276 9461:CNS Drugs 9383:March 31, 9177:236451973 9041:209434994 9015:2215-0366 8958:2042-6305 8695:1570-159X 8640:0924-977X 8587:0253-7613 8538:1461-1457 8140:CNS Drugs 7244:: 17–28. 6948:1469-5111 6887:1745-1701 6704:208792724 6549:: 55–62. 6148:881019573 5909:Sulpiride 5847:Withdrawn 5659:Melperone 5584:Clozapine 5484:Asenapine 5428:approved 5392:Australia 5348:psychosis 5228:viscosity 5226:. = Low- 4393:13.7-15.9 4195:24 (Oral) 4171:23 (Oral) 4090:Melperone 4024:1340-2800 3970:Clozapine 3947:>99.7% 3894:Asenapine 3794:Excretion 3781:in hours) 3706:Moderate 3649:++++/+++ 3643:++++ (RC) 3510:Sulpiride 3472:++/+ (PA) 3363:++/+ (PA) 3324:++++/+++ 3185:Melperone 3023:Clozapine 2988:++++ (PA) 2980:++++ (PA) 2932:++++ (PA) 2814:Asenapine 2791:+++ (PA) 2767:++++ (PA) 2455:asenapine 2433:serotonin 2356:serotonin 2268:serotonin 2187:Jaundice 2147:Sulpiride 1873:dysphagia 1706:Melperone 1574:pneumonia 1528:Clozapine 1432:Asenapine 1426:(0.1–1%) 1274:prolactin 1220:metformin 1196:asenapine 1045:prolactin 803:Melperone 737:Clozapine 671:Asenapine 503:psychotic 433:valproate 353:metabolic 313:Clozapine 260:agitation 139:Australia 99:serotonin 49:clozapine 19974:lisuride 19948:pimozide 19944:loxapine 19783:LY-53857 19734:zotepine 19639:Triptans 19503:loxapine 19354:BVT-5182 19197:Hypidone 19175:lisuride 18987:RS-67532 18982:RS-39604 18972:L-Lysine 18809:LY-53857 18759:loxapine 18652:CSP-2503 18573:YM-31636 18523:SR-57227 18513:RS-56812 18467:Alcohols 18369:pimozide 18365:loxapine 18333:Tramadol 18152:LY-53857 18094:zotepine 17987:psilocin 17803:LA-SS-Az 17799:lisuride 17728:A-372159 17702:5-Fl-αMT 17698:5-Cl-αMT 17428:LY-53857 17424:lisuride 17314:psilocin 17139:cloforex 17126:Aminorex 17016:pimozide 17008:loxapine 16937:TGBA01AD 16737:LY-53857 16709:CSP-2503 16693:zotepine 16555:AC-90179 16520:psilocin 16330:LA-SS-Az 16326:lisuride 16242:AL-34662 16216:5-Fl-αMT 16212:5-Cl-αMT 16172:2C-B-FLY 16108:25I-NBOH 16104:25I-NBMD 16007:Triptans 15979:lysergol 15925:lysergol 15870:Triptans 15813:lysergol 15809:lisuride 15675:5-Et-DMT 15621:Triptans 15616:TGBA01AD 15591:L-772405 15586:L-694247 15581:GR-46611 15503:lisuride 15317:Triptans 15252:CP-94253 15247:CP-93129 15084:GR-46611 15054:CSP-2503 15035:pindolol 14945:Urapidil 14935:TGBA01AD 14925:psilocin 14858:S-14,506 14778:Hypidone 14758:F-15,599 14733:F-11,461 14711:lisuride 14671:Dopamine 14632:gepirone 14362:Tiapride 14272:LEK-8829 14197:Azapride 14115:Itopride 14049:Zotepine 13728:Pimozide 13703:Perazine 13678:Moperone 13668:Loxapine 13378:OSU-6162 13363:Ketamine 13293:A-412997 13141:Ciladopa 13136:2-OH-NPA 13110:Lisuride 13012:Agonists 12976:Odapipam 12961:Ecopipam 12945:Zotepine 12809:Loxapine 12542:Lisuride 12537:LEK-8829 12506:Trepipam 12471:6-Br-APB 12460:Agonists 12296:Zotepine 12156:Atypical 12126:Loxapine 12075:Tiapride 12032:Disputed 11875:Perazine 11800:Pimozide 11757:Moperone 11609:16180961 11573:25824037 11460:"Search" 11356:36821764 11307:17015810 11266:46319827 11258:17242588 11223:16498489 10844:36697288 10792:23464075 10784:20030420 10629:24157985 10594:24251712 10586:10647096 10548:19823183 10507:20878941 10499:18667366 10278:12893717 10270:20404009 10195:18308814 10160:19086256 9869:16310183 9834:11800154 9826:18597077 9657:16774655 9532:43855244 9481:11463136 9437:23596605 9238:32356562 9169:34311625 9092:28883731 9033:31860457 8974:13769615 8966:29697278 8917:43719333 8909:23499243 8858:14747245 8813:37288246 8805:18332662 8767:11873706 8713:22942882 8648:10974610 8605:23112432 8546:15231024 8497:22952071 8448:23929443 8407:20065205 8302:18458771 8253:15156241 8187:UpToDate 8168:11543666 8160:23812802 8125:21689438 8074:23324764 8066:25283309 8020:19851515 7969:25512763 7961:21851976 7925:21191528 7881:19727265 7783:24264818 7775:25963405 7737:36295165 7729:15232326 7681:23017200 7630:26085041 7555:19687129 7514:23554581 7460:21154393 7418:UpToDate 7288:18515977 7219:22936056 7176:18332660 7141:16585435 7105:16172203 7064:11099280 7015:21254289 6966:31974576 6905:26338693 6848:27388573 6807:20704164 6780:17619525 6753:20954430 6696:19700006 6661:27802977 6620:25528757 6563:27293137 6478:22376048 6404:21954480 6361:April 3, 6338:19951248 6330:19058841 6295:18185824 6247:32085212 6239:23810019 6190:19058842 6115:23006237 6069:See also 5959:Zotepine 5418:approved 5408:approved 5398:approved 5388:approved 5378:approved 5251:Sources: 5247:DrugBank 5181:Viscoleo 5157:1–2 days 5147:Viscoleo 5106:Atypical 5054:8.5–11.6 5038:Viscoleo 4943:8.1–10.1 4923:Atypical 4885:Meclopin 4853:Atypical 4677:Viscoleo 4640:Viscoleo 4562:Atypical 4547:7.9–10.0 4527:Atypical 4524:Aristada 4508:multiple 4386:Zotepine 4353:7 (oral) 4232:1.9-5.7 4155:6 (Oral) 4008:102-771 3810:(ng/mL) 3788:in L/kg) 3628:++++/+++ 3618:Zotepine 3583:+++ (PA) 3580:+++ (PA) 3492:++++/+++ 3147:+++ (PA) 2947:+++ (PA) 2830:+++ (PA) 2776:+++ (PA) 2770:+++ (PA) 2352:Receptor 2278:Receptor 1981:priapism 1869:priapism 1860:+/- (7%) 1347:Seizures 1297:Anti-ACh 1278:Sedation 1184:receptor 1176:receptor 1146:receptor 1114:diabetes 1053:dementia 979:Zotepine 264:dementia 236:diabetes 200:rigidity 58:Synonyms 19986:(e.g., 19972:(e.g., 19926:(e.g., 19908:(e.g., 19886:(e.g., 19869:SLV-314 19864:SLV-313 19757:(e.g., 19745:DR-4485 19684:(e.g., 19651:(e.g., 19641:(e.g., 19601:(e.g., 19594:E-55888 19544:(e.g., 19522:(e.g., 19497:(e.g., 19485:doxepin 19475:(e.g., 19461:(e.g., 19344:AVN-397 19339:AVN-322 19334:AVN-211 19329:AVN-101 19293:(e.g., 19286:ABT-354 19255:ST-1936 19209:(e.g., 19161:(e.g., 19124:(e.g., 19110:(e.g., 19054:(e.g., 19031:(e.g., 18816:(e.g., 18767:(e.g., 18757:(e.g., 18740:Thujone 18724:(e.g., 18611:(e.g., 18604:AS-8112 18563:toluene 18553:(e.g., 18535:(e.g., 18497:(e.g., 18471:butanol 18469:(e.g., 18406:(e.g., 18359:(e.g., 18345:(e.g., 18328:TIK-301 18300:(e.g., 18253:S-14671 18142:(e.g., 18044:(e.g., 18006:WAY-629 17957:(e.g., 17906:(e.g., 17892:(e.g., 17845:(e.g., 17815:LSD-Pip 17777:(e.g., 17755:(e.g., 17696:(e.g., 17662:2C-T-21 17640:(e.g., 17603:(e.g., 17580:TIK-301 17572:(e.g., 17549:(e.g., 17414:(e.g., 17346:(e.g., 17276:(e.g., 17251:(e.g., 17229:(e.g., 17190:(e.g., 17168:(e.g., 17133:(e.g., 17082:(e.g., 16994:(e.g., 16984:(e.g., 16954:(e.g., 16900:(e.g., 16888:S-14671 16788:KML-010 16731:(e.g., 16599:(e.g., 16572:(e.g., 16490:(e.g., 16457:(e.g., 16443:(e.g., 16386:(e.g., 16342:LSD-Pip 16296:(e.g., 16269:(e.g., 16210:(e.g., 16177:2CB-Ind 16166:2C-T-21 16144:(e.g., 16100:25I-NBF 16027:(e.g., 16009:(e.g., 15973:(e.g., 15919:(e.g., 15882:(e.g., 15872:(e.g., 15857:(e.g., 15807:(e.g., 15721:(e.g., 15665:(e.g., 15623:(e.g., 15553:(e.g., 15493:(e.g., 15432:(e.g., 15393:(e.g., 15350:(e.g., 15319:(e.g., 15274:(e.g., 15202:(e.g., 15129:S-15535 15119:NAN-190 15066:(e.g., 15001:(e.g., 14978:(e.g., 14895:(e.g., 14868:S-15535 14863:S-14671 14803:MKC-242 14753:F-15063 14748:F-14679 14743:F-13714 14738:F-12826 14693:(e.g., 14622:(e.g., 14584:(e.g., 14550:(e.g., 14227:F-15063 14065:AS-8112 13854:BL-1020 13683:Naranol 13453:RDS-127 13303:ABT-724 13298:ABT-670 13267:F-15063 13216:XP21279 12669:A-68930 12658:XP21279 12604:BCO-001 12568:A-86929 12563:A-77636 12303:Others: 12143:Others: 11890:BL-1020 11709:Typical 11214:1324958 11155:7185768 11120:3545764 11085:4992598 11033:1429660 10990:6143748 10945:6931472 10888:9485566 10836:7140807 10643:Roth BL 10562:Gobbi G 10464:2842163 10421:Fda.gov 10303:May 16, 9665:6267180 9524:8329149 9428:3623530 9229:7522687 9132:7234755 9083:5574691 9024:7029416 8704:3286851 8596:3480803 8488:3516138 8398:4598075 8293:2327229 8116:3152513 8099:: 101. 8011:2762364 7916:3010964 7872:2695730 7672:3549283 7655:: 160. 7621:4843798 7505:3595214 7393:. WebMD 7296:2669203 7006:3069498 6957:7177160 6896:4601722 6744:3085113 6611:4466178 6571:4907333 6469:3571677 6286:2139919 6198:1071537 5622:Refused 5343:above. 5263:History 5243:PubChem 5207:All by 5197:7.5–9.0 5176:Typical 5160:4.7–4.9 5142:Typical 5070:Typical 5033:Typical 5017:6.4–7.2 4996:Typical 4959:Typical 4908:8.5–8.7 4889:Typical 4838:7.2–7.9 4820:Typical 4804:5.2–5.8 4783:Typical 4767:6.4–7.4 4746:Typical 4730:7.2–9.0 4709:Typical 4693:7.2–9.2 4672:Typical 4668:Depixol 4635:Typical 4598:Typical 4582:4.9–5.2 4485:Vehicle 4174:390-487 4152:>60% 4005:1.5-2.5 3925:0.5-1.5 3673:Legend: 3663:++ (RC) 3660:++ (RC) 3634:++ (PA) 3589:+++(PA) 3432:+++/++ 3378:+++/++ 3341:+++/++ 3039:++ (PA) 2785:++ (PA) 2547:Release 2354:: When 2060:>30% 2055:>30% 1960:>30% 1899:>30% 1845:>30% 1795:>30% 1700:(2–4%) 1671:>30% 1654:(0.4%) 1652:syncope 1553:>30% 1400:anxiety 1299:effects 1002:Legend: 429:lithium 357:glucose 308:typical 208:potency 204:tremors 163:adjunct 145:of the 129:of the 19619:LP-211 19409:MS-245 19235:E-6837 19231:E-6801 18485:m-CPBG 18016:YM-348 17865:MK-212 17779:ALD-52 17658:2C-T-7 17654:2C-T-2 16483:TFMFly 16406:O-4310 16302:ALD-52 16298:1P-LSD 16262:DMBMPP 16162:2C-T-7 16158:2C-T-2 15159:UH-301 15099:Mefway 14367:UH-232 14347:SV-293 14183:Others 13333:BP-897 13284:Others 13064:UH-232 12952:Others 12665:Others 12372:WHO-EM 12325:Others 11607: 11571: 11449:Search 11354: 11346: 11305: 11264: 11256: 11221: 11211: 11153: 11118: 11083: 11042:444352 11040: 11030: 10988: 10943: 10886: 10842: 10834: 10790: 10782: 10627: 10592: 10584: 10546: 10505: 10497: 10462: 10396: 10362: 10328: 10276: 10268: 10201: 10193: 10158: 10114: 9918: 9867: 9832: 9824: 9780: 9715: 9688: 9663: 9655: 9618: 9579: 9530: 9522: 9487: 9479: 9435: 9425: 9236: 9226: 9175: 9167: 9129: 9090: 9080: 9039: 9031: 9021: 9013: 8972: 8964: 8956: 8915: 8907: 8856: 8811: 8803: 8765: 8711: 8701: 8693: 8656:276209 8654: 8646: 8638: 8603: 8593: 8585: 8544: 8536: 8495: 8485: 8446: 8405: 8395: 8356: 8346: 8300: 8290: 8251: 8244:353028 8241: 8166: 8158: 8123: 8113: 8072: 8064: 8018: 8008: 7967: 7959: 7941:Lancet 7923: 7913: 7879: 7869: 7781: 7773: 7735: 7727: 7679: 7669: 7628: 7618: 7553: 7512: 7502: 7458: 7323: 7294: 7286: 7217: 7182: 7174: 7139: 7103: 7062: 7052: 7013: 7003: 6964: 6954: 6946: 6903: 6893: 6885: 6846: 6805: 6778: 6751: 6741: 6702: 6694: 6676:Lancet 6659: 6618: 6608: 6569: 6561: 6476: 6466: 6425: 6402: 6336: 6328: 6310:Lancet 6293: 6283: 6245: 6237: 6219:Lancet 6196: 6188: 6170:Lancet 6146: 6136: 6113: 5402:Europe 5382:Canada 5288:, and 4501:single 4488:Dosage 4396:10-109 4370:CYP1A2 4368:& 4366:CYP3A4 4330:CYP2D6 4294:CYP2D6 4258:CYP3A4 4188:CYP3A4 4184:CYP2D6 4148:CYP2D6 4144:CYP1A2 4074:CYP3A4 4038:CYP3A4 4036:& 4034:CYP2D6 4002:50-60% 3998:CYP2D6 3994:CYP3A4 3990:CYP1A2 3954:CYP3A4 3918:UGT1A4 3916:& 3914:CYP1A2 3874:CYP3A4 3872:& 3870:CYP2D6 3657:+++/++ 3622:+++/++ 3600:+++/++ 3577:+++/++ 3568:+++/++ 3438:+++/++ 3417:+ (PA) 3386:+++/++ 3312:+++/++ 3309:+ (PA) 3255:+ (PA) 3201:+ (PA) 3170:+++/++ 3116:+++/++ 3093:+ (PA) 2907:+ (RC) 2904:+ (RC) 2773:+ (PA) 2465:, and 2216:20–30% 2050:20–30% 2040:10–20% 1952:10–20% 1942:20–30% 1850:20–30% 1840:10–20% 1790:20–30% 1785:20-30% 1775:20–30% 1679:20–30% 1633:10–20% 1588:(1%), 1558:20–30% 1533:20–30% 1457:10–20% 1383:10–20% 1373:10–20% 807:+++/++ 555:Autism 543:, and 527:, and 381:et al. 375:, and 363:, and 234:, and 224:stroke 159:autism 149:) for 141:, the 133:, the 96:) and 19614:LP-44 19609:LP-12 19584:AS-19 18856:BIMU8 18777:xenon 17924:TFMPP 17253:TFMPP 16478:TCB-2 16467:TFMPP 16431:RH-34 15343:TFMPP 14994:AV965 14813:NBUMP 14187:3-PPP 13288:3-PPP 13004:-like 12452:-like 11580:(PDF) 11549:(PDF) 11262:S2CID 11100:Drugs 10840:S2CID 10788:S2CID 10691:WebMD 10590:S2CID 10503:S2CID 10417:(PDF) 10274:S2CID 10223:(PDF) 10199:S2CID 9830:S2CID 9757:(PDF) 9750:(PDF) 9661:S2CID 9528:S2CID 9485:S2CID 9173:S2CID 9037:S2CID 8970:S2CID 8913:S2CID 8809:S2CID 8652:S2CID 8164:S2CID 8070:S2CID 7965:S2CID 7779:S2CID 7733:S2CID 7292:S2CID 7184:34935 7180:S2CID 7055:27538 6700:S2CID 6567:S2CID 6539:(PDF) 6509:(PDF) 6334:S2CID 6243:S2CID 6194:S2CID 5985:Notes 5803:(No) 5412:Japan 5254:Main: 5237:with 5205:Note: 4927:Water 4857:Water 4788:Water 4566:Water 4531:Water 4482:Class 4408:7-13% 4323:99.5% 4115:0.5–3 4100:7–9.9 4078:9-19% 3961:<2 3904:20-25 3727:+++++ 3714:High 3666:++++ 3504:++/+ 3395:++++ 3287:++++ 3162:++++ 3071:++++ 2953:++++ 2944:+++++ 2845:++++ 2808:++/+ 2737:++/+ 2563:Note: 2538:Terms 2310:VMPFC 2306:DLPFC 2221:0–10% 2208:0–10% 2203:0–10% 2198:0–10% 2065:0–10% 2045:0–10% 1965:0–10% 1947:0–15% 1855:0–10% 1832:0–10% 1800:0–10% 1780:0–15% 1638:0–10% 1625:0–10% 1620:0–10% 1615:0–10% 1538:0–15% 1462:0–10% 1452:0–10% 1447:0–10% 1437:0–10% 1388:0–10% 1368:0–10% 1363:0–10% 1272:High 1226:, or 1072:DSM-5 612:Mania 559:Both 509:MDD. 20053:and 19657:5-MT 19653:5-CT 19561:5-HT 19243:EMDT 19223:5-MT 19219:5-CT 19215:5-BT 19141:5-HT 19056:5-CT 19011:5-HT 18851:5-MT 18833:5-HT 18541:5-CT 18503:mCPP 18449:5-HT 18431:5-HT 18105:CEPC 17975:DiPT 17963:5-CT 17959:5-BT 17916:mCPP 17859:MMDA 17855:MDOH 17843:MDxx 17688:5-MT 17650:2C-I 17646:2C-E 17642:2C-B 17620:5-HT 17452:mCPP 17302:DiPT 17286:5-MT 17282:5-CT 17278:5-BT 17243:MMDA 17239:MDOH 17227:MDxx 17103:5-HT 16803:mCPP 16592:AMDA 16508:DiPT 16496:5-CT 16492:5-BT 16400:MMDA 16396:MDOH 16384:MDxx 16202:5-MT 16154:2C-I 16150:2C-E 16146:2C-B 16081:5-HT 16069:5-HT 16029:5-MT 15943:5-HT 15832:5-HT 15679:5-MT 15671:5-CT 15667:5-BT 15596:mCPP 15518:5-HT 15360:5-MT 15356:5-CT 15352:5-BT 15302:mCPP 15219:5-HT 15114:MPPF 14905:5-MT 14897:5-CT 14798:mCPP 14515:5-HT 14503:5-HT 14222:EEDQ 12966:EEDQ 12754:DPTQ 12749:DETQ 12738:PAMs 11700:N05A 11638:2013 11605:PMID 11588:2019 11569:PMID 11527:2018 11501:2018 11476:2018 11445:2018 11412:2018 11382:2018 11352:PMID 11344:ISSN 11303:PMID 11254:PMID 11219:PMID 11151:PMID 11116:PMID 11081:PMID 11038:PMID 10986:PMID 10941:PMID 10884:PMID 10832:PMID 10780:PMID 10749:2013 10724:2013 10699:2013 10663:2013 10625:PMID 10582:PMID 10544:PMID 10495:PMID 10460:PMID 10429:2016 10394:ISBN 10373:2016 10360:ISBN 10339:2016 10326:ISBN 10305:2016 10266:PMID 10234:2016 10191:PMID 10156:PMID 10125:2016 10112:ISBN 10091:2016 10066:2016 10041:2016 10015:2016 9985:2016 9959:2016 9929:2016 9916:ISBN 9895:2016 9865:PMID 9822:PMID 9791:2016 9778:ISBN 9713:ISBN 9686:ISBN 9653:PMID 9616:ISBN 9577:ISBN 9558:2016 9520:PMID 9477:PMID 9433:PMID 9385:2012 9234:PMID 9165:PMID 9088:PMID 9029:PMID 9011:ISSN 8962:PMID 8954:ISSN 8905:PMID 8854:PMID 8801:PMID 8763:PMID 8709:PMID 8691:ISSN 8644:PMID 8636:ISSN 8601:PMID 8583:ISSN 8542:PMID 8534:ISSN 8493:PMID 8444:PMID 8403:PMID 8354:OCLC 8344:ISBN 8298:PMID 8249:PMID 8195:2013 8156:PMID 8121:PMID 8062:PMID 8016:PMID 7957:PMID 7921:PMID 7877:PMID 7833:2023 7808:2018 7771:PMID 7725:PMID 7677:PMID 7626:PMID 7581:2018 7551:PMID 7510:PMID 7456:PMID 7426:2013 7399:2013 7352:2022 7321:ISBN 7284:PMID 7215:PMID 7172:PMID 7137:PMID 7101:PMID 7060:PMID 7011:PMID 6962:PMID 6944:ISSN 6901:PMID 6883:ISSN 6844:PMID 6803:PMID 6776:PMID 6749:PMID 6692:PMID 6657:PMID 6616:PMID 6559:PMID 6521:2009 6492:link 6474:PMID 6423:ISBN 6400:PMID 6382:JAMA 6363:2011 6326:PMID 6291:PMID 6235:PMID 6186:PMID 6144:OCLC 6134:ISBN 6111:PMID 5953:Yes 5928:Yes 5903:Yes 5878:Yes 5828:Yes 5753:Yes 5728:Yes 5653:Yes 5603:Yes 5503:Yes 5478:Yes 5453:Yes 5426:MHRA 5416:PMDA 5386:HPFB 5296:and 5245:and 4514:Ref 4511:logP 4390:Oral 4314:Oral 4262:100% 4248:6-14 4242:Oral 4208:Oral 4134:1000 4064:6173 4058:Oral 4018:Oral 3980:4.67 3974:Oral 3938:Oral 3820:Oral 3771:Drug 3719:++++ 3698:Low 3646:++++ 3640:++++ 3595:+++ 3586:++++ 3520:++++ 3517:++++ 3481:++++ 3478:++++ 3423:++++ 3383:++++ 3357:++/+ 3354:++/+ 3315:++++ 3284:++++ 3281:++++ 3261:++++ 3195:++++ 3153:++++ 3138:++++ 3125:+++ 3113:++++ 3065:++++ 3059:++++ 3054:+++ 3048:++++ 3045:++++ 3042:++/+ 3017:+++ 2968:+++ 2935:++++ 2899:+/- 2878:++++ 2875:++++ 2862:+++ 2842:++++ 2839:++++ 2836:++++ 2824:++++ 2796:++/+ 2716:++++ 2713:++++ 2648:5-HT 2640:5-HT 2632:5-HT 2624:5-HT 2616:5-HT 2608:5-HT 2518:and 2497:5-HT 2490:5-HT 2448:5-HT 2441:5-HT 2422:5-HT 2413:5-HT 2397:5-HT 2379:5-HT 2348:5-HT 2340:and 2308:and 2244:The 1761:and 1202:and 1180:5-HT 1172:5-HT 1170:and 1134:5-HT 1132:and 1112:and 964:++/+ 961:++/+ 665:+++ 659:++/+ 563:and 505:and 439:and 431:and 423:and 339:NIMH 282:(an 278:and 143:MHRA 115:and 105:SDAs 94:SGAs 80:The 19603:LSD 19179:LSD 19041:LSD 18499:BZP 17983:DPT 17979:DMT 17971:DET 17912:BZP 17823:LSP 17819:LSH 17811:LSD 17807:LSB 17769:DOM 17765:DOI 17761:DOC 17757:DOB 17753:DOx 17722:αMT 17718:αET 17638:2Cs 17310:DPT 17306:DMT 17298:DET 17182:DOM 17178:DOI 17174:DOC 17170:DOB 17166:DOx 16516:DPT 16512:DMT 16504:DET 16459:BZP 16350:LSP 16346:LSH 16338:LSD 16334:LSB 16283:DOM 16279:DOI 16275:DOC 16271:DOB 16267:DOx 16236:αMT 16232:αET 16142:2Cs 15687:DMT 15571:LSD 15364:DMT 14913:DMT 14715:LSD 13115:LSD 11561:doi 11557:460 11334:doi 11293:doi 11246:doi 11209:PMC 11201:doi 11143:doi 11108:doi 11028:PMC 11020:doi 10933:doi 10929:279 10876:doi 10824:doi 10772:doi 10617:doi 10613:722 10574:doi 10534:doi 10487:doi 10483:142 10452:doi 10448:149 10258:doi 10254:334 10183:doi 10148:doi 9857:doi 9853:526 9814:doi 9810:200 9645:doi 9641:114 9512:doi 9469:doi 9423:PMC 9415:doi 9224:PMC 9214:hdl 9204:doi 9157:doi 9127:PMC 9119:doi 9078:PMC 9068:doi 9019:PMC 9001:doi 8944:doi 8897:doi 8893:146 8844:doi 8793:doi 8753:doi 8699:PMC 8683:doi 8628:doi 8591:PMC 8573:doi 8524:doi 8483:PMC 8475:doi 8471:169 8434:doi 8430:205 8393:PMC 8385:doi 8381:170 8288:PMC 8280:doi 8239:PMC 8231:doi 8148:doi 8111:PMC 8101:doi 8054:doi 8050:130 8006:PMC 7996:doi 7949:doi 7945:378 7911:PMC 7867:PMC 7763:doi 7717:doi 7667:PMC 7657:doi 7616:PMC 7608:doi 7604:172 7541:doi 7537:166 7500:PMC 7490:doi 7448:doi 7317:303 7276:doi 7246:doi 7207:doi 7164:doi 7129:doi 7125:163 7091:doi 7087:353 7050:PMC 7042:doi 7038:321 7034:BMJ 7001:PMC 6993:doi 6952:PMC 6936:doi 6891:PMC 6875:doi 6834:doi 6830:209 6739:PMC 6731:doi 6684:doi 6680:374 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