254:, produced a human vaccine for rabies during the 1960s and 1970s also on the WI-38 cell strain gifted to them by Leonard Hayflick. WI-38 provided to the rabies vaccine the same properties that it gave to the rubella vaccine. This rabies vaccine can be used as a preventive measure for people who have an increased risk of contracting rabies, as well as a treatment for those who have been exposed recently to the disease, preventing infection in nearly 100 percent of cases. Another vaccine that Plotkin co-developed, working with
496:
31:
245:
also of the Wistar. WI-38 provide the key elements for the successful
Rubella vaccine. The virus became attenuated when grown on WI-38; it was free of unwanted viruses and the vaccine proved to have minor side effects when compared with the HPV vaccine developed at the NIH. This WI-38 grown vaccine
266:
Dr. Plotkin has been a tireless advocate for the protection of humans, and children in particular, from preventable infectious diseases. His lifetime of work on vaccines has led to profound reductions in both morbidity and mortality not only in the United States, but throughout the world. His
262:, is for rotavirus. In 2006, the team's vaccine became part of the U.S. recommended vaccine schedule for babies. In the 1970s, Plotkin led the development of an experimental vaccine against CMV. This vaccine, developed using attenuated CMV, has yet to make it into commercial production.
1208:
267:
unbending adherence to the principle of being guided by outstanding science has led him to be admired by his peers. He demonstrates the combination of scholar, scientist and public servant exemplified by Dr.
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785:
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752:
188:. Deciding to dedicate his life to being a physician and research scientist, Plotkin graduated from Bronx Science in 1948. He then earned his bachelor's degree from
1378:
1279:
938:
168:
in New York City. While attending Bronx
Science, at the age of 15, he read a pair of books that greatly influenced his future education and career choices:
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1148:
1348:
1438:
2488:
241:, a fetal-derived human cell line), which was released to the public in 1969. The enabling technology was the WI-38 cell strain gifted to Plotkin by
998:
2623:
394:
385:
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1525:
1676:
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648:
2603:
968:
164:
Plotkin was born and raised in New York City, the son of Jewish parents, Lee and Joseph
Plotkin, who emigrated from England. He attended
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687:
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2068:
379:
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1123:
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310:
2608:
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904:
874:
American Men & Women of
Science: A Biographical Directory of Today's Leaders in Physical, Biological and Related Sciences
825:
2073:
2105:
1862:
1788:
1641:
1241:
298:
1468:
111:, as well as biotechnology firms, non-profits and governments. In the 1960s, he played a pivotal role in discovery of a
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1827:
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881:
237:(CMV). He developed a vaccine for rubella, based upon the RA 27/3 strain of the virus (also developed by Plotkin using
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145:
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1783:
1213:
627:
592:
408:
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1971:
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1371:"Dr. Stanley A. Plotkin to Receive the Hamdan Award for Medical Research Excellence in the Field of Vaccines"
481:
294:
197:
66:
1028:
847:
429:
316:
1006:
107:(born May 12, 1932) is an American physician who works as a consultant to vaccine manufacturers, such as
127:. Plotkin was a member of Wistar’s active research faculty from 1960 to 1991. Today, in addition to his
2093:
1535:
1518:
1113:"James D. Bruce Memorial Award for Distinguished Contributions in Preventive: Full Lists of Recipients"
423:
416:
1995: Ed
Nowakowski Senior Memorial Clinical Virology Award, Pan American Society for Clinical Virology
201:
136:
476:
Plotkin and his wife, Susan, have two children, Michael and Alec. In 1957, Plotkin wanted to join the
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348:
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1972–1990: Director of infectious diseases and senior physician, Children's
Hospital of Philadelphia
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1974–1991: Professor of pediatrics and microbiology, School of
Medicine, University of Pennsylvania
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448:
180:
616:
Orenstein, Stanley (1999). "Smallpox and
Vaccinia". In Stanley A. Plotkin, Walter A. (ed.).
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8:
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1435:
Short film- Stanley
Plotkin: Pioneering the use of fetal cells to make rubella vaccine
1272:"Wistar Emeritus Professor Stanley A. Plotkin, M.D., Elected to Institute of Medicine"
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2013:
1907:
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877:
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2110:
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120:
1949:
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Billion-dollar programme aims to cut vaccine-development time from 12 years to one
912:
2211:
2018:
1976:
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2008:
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108:
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1991:
1986:
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led to the eradication of the disease in the United States, according to the
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54:
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602:
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1981:
1922:
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568:
124:
2297:
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2148:
1954:
1842:
1810:
1736:
1598:
1489:
1481:
1401:"Dr. Charles MĂ©rieux Award for Achievement in Vaccinology and Immunology"
724:
413:
1993: Distinguished
Physician Award, Pediatric Infectious Disease Society
288:
1186:
484:. He eventually realized his dream of learning to fly at the age of 74.
375:
Associate chairman, department of pediatrics, University of Pennsylvania
344:
1984–1986: President, medical staff, Children's Hospital of Philadelphia
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807:
528:
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worked on several vaccines; chief among them are vaccines for rubella,
132:
80:
2472:
2043:
1916:
1485:
1408:
1315:
1060:"Davos launch for coalition to prevent epidemics of emerging viruses"
230:
1342:"The Wistar Gala Honors Brian H. Dovey and Stanley A. Plotkin, M.D."
813:
Vaccinated: One Man's Quest to Defeat the World's Deadliest Diseases
2314:
2307:
2302:
2272:
2028:
1964:
1959:
1302:"How to Nominate for ASM Awards and Prize, Past Laureates, page 24"
1209:"Dr. Plotkin receives French award for role in developing vaccines"
973:
Duke Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery
480:
so that he could learn to fly, but instead he went to work for the
338:
328:
1965–1972: Associate physician, Children's Hospital of Philadelphia
128:
939:"Prominent Virologist Stanley Plotkin Joins GVN as Senior Advisor"
2033:
1477:
1036:
222:
143:, is the standard reference on the subject. He is an editor with
116:
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76:
30:
360:
2006: Professor emeritus of virology, University of Pennsylvania
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786:
Perelman School of Medicine at the University of Pennsylvania
436:
Perelman School of Medicine at the University of Pennsylvania
238:
1631:
564:"Brasil, Cartões de Imigração, 1961: Stanley Alan Plotkin"
758:. University of Pennsylvania Medical Center. p. 29
457:
2013-2014: Hamdan Award for Medical Research Excellence
933:
519:
250:, in 2005. Plotkin, working with Tadeusz Wiktor and
419:
1998: Chevalier of the French Legion of Honor Medal
131:appointment at Wistar, he is emeritus professor of
1316:"Maxwell Finland Award for Scientific Achievement"
1091:"New vaccine coalition aims to ward off epidemics"
816:, New York, New York: HarperCollins Inc, pp.
2489:Cedillo v. Secretary of Health and Human Services
842:
840:
838:
836:
685:
393:2017: Scientific advisor (and co-founder) of the
303:1959–1973: Instructor, then associate professor,
276:Vijay B. Samant, President and CEO of Vical, Inc.
2575:
1122:. American College of Physicians. Archived from
745:
649:"Dr. Stanley Plotkin talks CMV vaccine research"
622:(3rd ed.). Philadelphia: W.B. Saunders Co.
583:Plotkin, Stanley A; Orenstein, Walter A (2004).
582:
1003:Johns Hopkins Bloomberg School of Public Health
430:Institute of Medicine of the National Academies
395:Coalition for Epidemic Preparedness Innovations
386:Johns Hopkins Bloomberg School of Public Health
833:
305:School of Medicine, University of Pennsylvania
206:School of Medicine, University of Pennsylvania
1454:
1057:
2634:Members of the National Academy of Medicine
1405:National Foundation for Infectious Diseases
1320:National Foundation for Infectious Diseases
781:"Distingished [sic] Graduate Award"
732:National Foundation for Infectious Diseases
347:1991–1998: Medical and scientific director
217:The Wistar Institute of Anatomy and Biology
159:
1461:
1447:
1183:Pan-American Society for Clinical Virology
1088:
775:
773:
719:
717:
715:
713:
643:
641:
639:
357:2003: Professor emeritus, Wistar Institute
248:Centers for Disease Control and Prevention
29:
1339:
615:
464:Award for Achievement in Vaccinology and
1433:https://hillemanfilm.com/stanley-plotkin
681:
679:
677:
675:
673:
671:
669:
487:
454:2013: Caspar Wistar Medal of Achievement
2624:The Bronx High School of Science alumni
1082:
770:
710:
636:
289:Cleveland Metropolitan General Hospital
281:
2576:
1242:"The Albert B. Sabin Gold Medal Award"
1120:Awards, Masterships & Competitions
899:
897:
895:
893:
380:Center for HIV/AIDS Vaccine Immunology
1442:
1153:Pediatric Infectious Diseases Society
871:
806:
666:
407:1987: James D. Bruce Memorial Award,
865:
434:2007: Distinguished Graduate Award,
890:
311:Children's Hospital of Philadelphia
299:United States Public Health Service
13:
2604:University of Pennsylvania faculty
2516:Eradication of infectious diseases
2273:Androvax (androstenedione albumin)
1051:
444:, American Society of Microbiology
14:
2645:
2106:Respiratory syncytial virus (RSV)
1426:
1058:Clive Cookson (18 January 2017).
872:Nemeh, Katherine H., ed. (2014).
686:Christian H. Ross (13 Apr 2017).
317:Hospital for Sick Children London
151:American Society for Microbiology
2495:Alternative vaccination schedule
1470:Artificial induction of immunity
1407:. 29 August 1999. Archived from
494:
471:
323:Joseph P. Kennedy Jr. Foundation
192:in 1952 and went on to earn his
166:The Bronx High School of Science
2619:20th-century American educators
1393:
1363:
1333:
1308:
1294:
1264:
1234:
1201:
1171:
1141:
1105:
1089:John Cohen (2 September 2016).
1021:
991:
961:
927:
876:(32nd ed.). p. 1434.
692:The Embryo Project Encyclopedia
688:"Stanley Alan Plotkin (1932- )"
587:. Philadelphia, Pa.: Saunders.
442:Maurice Hilleman/Merck Laureate
146:Clinical and Vaccine Immunology
2327:Ovandrotone albumin (Fecundin)
1340:Ben Leach (11 November 2013).
800:
609:
576:
556:
409:American College of Physicians
200:in 1956. Plotkin received his
1:
1863:Group B streptococcal disease
1682:Vaccines for Children Program
909:Agence de Médecine Préventive
550:
482:Epidemic Intelligence Service
295:Epidemic Intelligence Service
198:SUNY Downstate Medical Center
67:SUNY Downstate Medical Center
2609:American medical researchers
1218:. 1 Aug 1998. Archived from
535:(sixth ed.). Saunders.
390:Scientific advisor, Mymetics
149:, which is published by the
7:
1216:News & Journals Gateway
969:"Scientific Advisory Board"
221:During his time at Wistar,
10:
2650:
451:for Scientific Achievement
424:Albert B. Sabin Gold Medal
137:University of Pennsylvania
2534:
2503:
2442:
2374:
2265:
2237:
2204:
1878:
1709:
1702:
1621:
1549:
1501:
1149:"Distinguished Physician"
401:
363:2006: Executive advisor,
349:Pasteur Merieux Connaught
211:
94:
86:
72:
62:
37:
28:
21:
1858:Clostridioides difficile
725:"Stanley A. Plotkin, MD"
337:1974–1991: Professor of
160:Early life and education
2116:Tick-borne encephalitis
1179:"Past Award Recipients"
653:National CMV Foundation
119:virus while working at
2629:American immunologists
2584:American pediatricians
2526:List of vaccine topics
1526:Mathematical modelling
935:Florence Pat Haseltine
753:"PENN MED SPRING 2002"
428:2005: Election to the
369:2014: Senior advisor,
279:
2521:Vaccinate Your Family
1972:Japanese encephalitis
488:Selected publications
449:Maxwell Finland Award
315:1962–1963: Resident,
264:
2614:American virologists
2404:John Franklin Enders
999:"Stanley A. Plotkin"
943:Global Virus Network
371:Global Virus Network
282:Other positions held
105:Stanley Alan Plotkin
23:Stanley Alan Plotkin
1590:Virus-like particle
1514:Vaccine ingredients
1304:. February 1, 2023.
937:(14 January 2014).
384:Adjunct professor,
190:New York University
2561:Never to phase III
2360:Hexavalent vaccine
2174:Epstein–Barr virus
2069:Oxford–AstraZeneca
1762:NmVac4-A/C/Y/W-135
504:has a profile for
353:Marnes-la-Coquette
341:, Wistar Institute
287:1956: Internship,
16:American physician
2571:
2570:
2483:Vaccines and SIDS
2370:
2369:
2144:Hepatitis A and B
2120:Varicella zoster
1582:Subunit/component
1381:on 9 October 2015
1222:on 14 August 2017
1009:on 14 August 2017
949:on 14 August 2017
915:on 14 August 2017
827:978-0-06-122795-0
698:on 14 August 2017
525:Orenstein, Walter
510:
102:
101:
2641:
2462:MMR autism fraud
2409:Maurice Hilleman
2394:Hilary Koprowski
1707:
1706:
1463:
1456:
1449:
1440:
1439:
1421:
1420:
1418:
1416:
1397:
1391:
1390:
1388:
1386:
1377:. Archived from
1367:
1361:
1360:
1358:
1356:
1351:on 4 August 2017
1347:. Archived from
1337:
1331:
1330:
1328:
1326:
1312:
1306:
1305:
1298:
1292:
1291:
1289:
1287:
1278:. Archived from
1268:
1262:
1261:
1259:
1257:
1252:on 5 August 2017
1248:. Archived from
1238:
1232:
1231:
1229:
1227:
1205:
1199:
1198:
1196:
1194:
1189:on 5 August 2017
1185:. Archived from
1175:
1169:
1168:
1166:
1164:
1159:on 5 August 2017
1155:. Archived from
1145:
1139:
1138:
1136:
1134:
1129:on 5 August 2017
1128:
1117:
1109:
1103:
1102:
1086:
1080:
1079:
1074:
1072:
1055:
1049:
1048:
1046:
1044:
1035:. Archived from
1025:
1019:
1018:
1016:
1014:
1005:. Archived from
995:
989:
988:
986:
984:
975:. Archived from
965:
959:
958:
956:
954:
945:. Archived from
931:
925:
924:
922:
920:
911:. Archived from
901:
888:
887:
869:
863:
862:
860:
858:
844:
831:
830:
804:
798:
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795:
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765:
763:
757:
749:
743:
742:
740:
738:
729:
721:
708:
707:
705:
703:
694:. Archived from
683:
664:
663:
661:
659:
645:
634:
633:
613:
607:
606:
580:
574:
573:
560:
546:
521:Plotkin, Stanley
508:
507:Stanley Plotkin
498:
497:
309:1961: Resident,
277:
252:Hilary Koprowski
243:Leonard Hayflick
155:Washington, D.C.
121:Wistar Institute
51:
47:
45:
33:
19:
18:
2649:
2648:
2644:
2643:
2642:
2640:
2639:
2638:
2574:
2573:
2572:
2567:
2566:
2551:Clinical trials
2530:
2499:
2438:
2414:Stanley Plotkin
2376:
2366:
2278:Cancer vaccines
2261:
2255:Schistosomiasis
2233:
2227:Trypanosomiasis
2200:
2164:Cytomegalovirus
2074:Pfizer–BioNTech
1874:
1698:
1647:Vaccine wastage
1617:
1545:
1497:
1467:
1429:
1424:
1414:
1412:
1399:
1398:
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1384:
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1338:
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1314:
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1207:
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1177:
1176:
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1147:
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1142:
1132:
1130:
1126:
1115:
1111:
1110:
1106:
1087:
1083:
1070:
1068:
1065:Financial Times
1056:
1052:
1042:
1040:
1027:
1026:
1022:
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1010:
997:
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992:
982:
980:
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966:
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932:
928:
918:
916:
903:
902:
891:
884:
870:
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856:
854:
846:
845:
834:
828:
805:
801:
791:
789:
779:
778:
771:
761:
759:
755:
751:
750:
746:
736:
734:
727:
723:
722:
711:
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684:
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657:
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637:
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614:
610:
595:
581:
577:
562:
561:
557:
553:
543:
516:
515:
514:
499:
495:
490:
474:
462:Charles MĂ©rieux
404:
293:1957: Officer,
284:
278:
275:
269:Maxwell Finland
235:cytomegalovirus
219:
214:
181:Microbe Hunters
162:
63:Alma mater
58:
52:
49:
43:
41:
24:
17:
12:
11:
5:
2647:
2637:
2636:
2631:
2626:
2621:
2616:
2611:
2606:
2601:
2596:
2591:
2589:Vaccinologists
2586:
2569:
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2500:
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2465:
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2431:
2429:Katalin KarikĂł
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2186:
2184:Herpes simplex
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2171:
2166:
2158:
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2138:
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2126:
2118:
2113:
2108:
2103:
2102:
2101:
2096:
2091:
2086:
2084:Sinopharm BIBP
2081:
2076:
2071:
2066:
2061:
2056:
2051:
2046:
2041:
2036:
2034:Bharat Biotech
2031:
2021:
2016:
2011:
2006:
2005:
2004:
1999:
1989:
1984:
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1962:
1952:
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2355:DTwP-HepB-Hib
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978:
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55:New York City
50:(age 92)
40:
36:
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27:
20:
2511:Epidemiology
2487:
2459:
2413:
2345:DTaP-IPV/Hib
2136:Yellow fever
2049:EpiVacCorona
1806:Tuberculosis
1779:Pneumococcal
1747:Lyme disease
1575:Heterologous
1474:Immunization
1413:. Retrieved
1409:the original
1404:
1395:
1383:. Retrieved
1379:the original
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1349:the original
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696:the original
691:
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569:FamilySearch
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532:
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478:US Air Force
475:
265:
220:
179:
169:
163:
144:
140:
125:Philadelphia
104:
103:
2594:1932 births
2547:from market
2443:Controversy
2377:researchers
2293:Hepatitis B
2179:Hepatitis C
2124:Chicken pox
1950:Hepatitis E
1945:Hepatitis B
1940:Hepatitis A
1891:Chikungunya
1868:Shigellosis
1722:Brucellosis
1608:Therapeutic
1562:Inactivated
1502:Development
1490:Inoculation
1482:Vaccination
808:Offit, Paul
529:Offit, Paul
77:Vaccinology
48:12 May 1932
2578:Categories
2478:Thiomersal
2424:Paul Offit
2399:Jonas Salk
2375:Inventors/
2246:research:
2223:research:
2160:research:
2089:Skycovione
2079:Sanofi–GSK
2024:SARS-CoV-2
1935:Hantavirus
1901:rVSV-ZEBOV
1886:Adenovirus
1854:research:
1732:Diphtheria
1570:Attenuated
629:0721674437
594:0721696880
551:References
509:(Q7599873)
466:Immunology
460:2014: Dr.
260:Paul Offit
171:Arrowsmith
133:Pediatrics
81:immunology
44:1932-05-12
2557:Phase III
2545:Withdrawn
2473:Pox party
2283:ALVAC-CEA
2205:Protozoan
2094:Sputnik V
2044:CoronaVac
2014:Rotavirus
1917:Pandemrix
1769:Pertussis
1710:Bacterial
1594:Synthetic
1557:Conjugate
1509:Adjuvants
1486:Infection
848:"History"
792:6 October
762:6 October
231:rotavirus
208:in 1963.
204:from the
2315:Prostvac
2308:Gardasil
2303:Cervarix
2250:Hookworm
2129:Shingles
2111:Smallpox
2029:Corbevax
1965:Gardasil
1960:Cervarix
1703:Vaccines
1657:Schedule
1628:Global:
1536:Timeline
1478:Vaccines
1385:4 August
1355:4 August
1325:9 August
1286:4 August
1033:Mymetics
857:4 August
810:(2007),
737:9 August
658:9 August
619:Vaccines
603:51811284
585:Vaccines
533:Vaccines
531:(2012).
378:Member,
339:virology
274:—
141:Vaccines
129:emeritus
115:against
95:Children
2504:Related
2450:General
2212:Malaria
2099:Valneva
2064:Novavax
2059:Moderna
2054:Janssen
2039:CanSino
2019:Rubella
1977:Measles
1848:Td/Tdap
1818:Typhoid
1801:Tetanus
1796:Q fever
1727:Cholera
1717:Anthrax
1586:Peptide
1550:Classes
1531:Storage
1101:(6303).
1095:Science
1071:6 March
1029:"About"
502:Scholia
325:scholar
223:Plotkin
135:at the
117:rubella
113:vaccine
2540:WHO-EM
2460:Lancet
2337:TA-NIC
2322:NicVAX
2169:Dengue
2009:Rabies
1835:Typhus
1774:Plague
1652:Policy
1613:Toxoid
1541:Trials
1415:14 Aug
1375:Wistar
1345:Wistar
1276:Wistar
1226:14 Aug
1043:14 Aug
1013:14 Aug
983:14 Aug
953:14 Aug
919:14 Aug
880:
852:Wistar
824:
702:14 Aug
626:
601:
591:
539:
447:2009:
440:2009;
422:2002:
402:Awards
397:(CEPI)
321:1964:
233:, and
227:rabies
212:Career
87:Spouse
57:, U.S.
2468:NCVIA
2332:TA-CD
2266:Other
2217:RTS,S
1997:Sabin
1992:Polio
1987:Mumps
1896:Ebola
1879:Viral
1828:ViCPS
1823:Ty21a
1757:MeNZB
1687:VAERS
1637:NITAG
1566:Live
1256:5 Aug
1246:Sabin
1193:5 Aug
1163:5 Aug
1133:5 Aug
1127:(PDF)
1116:(PDF)
818:78–89
756:(PDF)
728:(PDF)
239:WI-38
2194:Zika
2154:MMRV
2002:Salk
1982:Mpox
1928:LAIV
1923:H5N1
1913:H1N1
1789:PPSV
1672:ACIP
1668:US:
1642:SAGE
1603:mRNA
1519:list
1417:2017
1387:2017
1357:2017
1327:2017
1288:2017
1258:2017
1228:2017
1195:2017
1165:2017
1135:2017
1073:2020
1045:2017
1015:2017
985:2017
955:2017
921:2017
878:ISBN
859:2017
822:ISBN
794:2017
764:2017
739:2017
704:2017
660:2017
624:ISBN
599:OCLC
589:ISBN
537:ISBN
258:and
178:and
38:Born
2455:MMR
2298:HPV
2288:BCG
2189:HIV
2149:MMR
1955:HPV
1908:Flu
1811:BCG
1784:PCV
1737:Hib
1692:VSD
1599:DNA
1494:J07
1214:AAP
1099:353
202:GME
196:at
184:by
174:by
153:in
123:in
2580::
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Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.