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251:. Spanning the fields of science and medicine, he was Canada's first medical geneticist, one of the creators of the discipline of medical genetics in North America, and laid the foundations in the field of Genetic Counselling, which has enhanced the lives of patients worldwide. Among his many accomplishments, Fraser pioneered work in the genetics of cleft palate and popularized the concept of multifactorial disease.
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Before Fraser took the stage, genetics and medicine were two very separate fields. There was no vision for the potential of genetics in human medicine. But very soon, Fraser turned his attention from fruit flies and mice to human genetics, and became the founder of the first
Canadian medical genetics
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Fraser made contributions in three areas. He collected data on recurrence risks for a number of pediatric conditions, to answer the questions of the parents of affected children. He helped develop the principles of genetic counseling. He showed that cortisone, injected into pregnant mice, caused
263:, he returned with his family to Canada when he was an infant. After a few years in Dublin, where his father, Frank Wise Fraser was Canadian Trade Commissioner, the family moved to Jamaica, where he received his primary and secondary school education at
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cleft palates in the offspring, and that the frequency of induced clefts varied with the genotype, thus bringing genetics into teratology. From this he developed the multifactorial threshold model that underlies many common familial conditions.
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He has been awarded four honorary doctorates, from Acadia
University (1967), SUNY at Potsdam, Dalhousie University (2003) and McGill University (2010).
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1979 Founding co-director of the
Medical Research Council of Canada Group in Medical Genetics, the longest lasting group in the history of the MRC.
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Fraser has served as president of the major North
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department in a paediatric hospital, named the F. Clarke Fraser
Clinical Genetics Centre at McGill University in 1995.
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464:"Obituary: Clarke Fraser made pioneering discoveries in McGill's 'mouse room'"
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1952-82 Founder and
Director of the Department of Medical Genetics at the
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1970-82 was the Molson
Professor of Genetics in the Department of Biology.
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Multifactorial threshold model that underlies some familial conditions
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1979–82, Professor in the McGill Centre for Human Genetics.
247:(29 March 1920 – 17 December 2014) was a Canadian medical
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Academic staff of the Memorial University of Newfoundland
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332:1982–85, Professor of Clinical Genetics at
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80:Learn how and when to remove this message
530:Osler Library of the History of Medicine
43:This article includes a list of general
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1462:Fellows of the Royal Society of Canada
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494:archivalcollections.library.mcgill.ca
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1472:Academic staff of McGill University
334:Memorial University of Newfoundland
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49:it lacks sufficient corresponding
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1492:People educated at Munro College
1487:People from Norwich, Connecticut
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1482:Officers of the Order of Canada
429:"Canadian Medical Hall of Fame"
391:"Canadian Who's Who 1997 entry"
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462:Fitterman, Lisa (2015-01-21).
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361:1999 Government of Quebec's
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572:Canadian Medical Hall of Fame
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370:Canadian Medical Hall of Fame
327:Montreal Children's Hospital
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1411:Marie-Marguerite d'Youville
395:University of Toronto Press
27:Canadian medical geneticist
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521:The Canadian Encyclopedia
299:but did not go overseas.
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1186:William Thornton Mustard
1053:Charles Philippe Leblond
490:"F. Clarke Fraser Fonds"
297:Royal Canadian Air Force
223:Royal Canadian Air Force
749:William Arthur Cochrane
349:Royal Society of Canada
64:more precise citations.
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1166:Frederick Montizambert
671:Wilfred Gordon Bigelow
526:F. Clarke Fraser fonds
368:2012 Elected to the
354:1984 Officer of the
347:1966 Fellow of the
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1309:F. Estelle R. Simons
807:Charles George Drake
734:Harvey Max Chochinov
363:Prix Wilder-Penfield
287:degree in 1950 from
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261:Norwich, Connecticut
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954:Emmett Matthew Hall
764:Douglas Harold Copp
626:Charles Thomas Beer
616:Henry J. M. Barnett
570:Inductees into the
517:Frank Clarke Fraser
295:, he served in the
269:Bachelor of Science
236:Frank Clarke Fraser
225:, McGill University
198:William Allan Award
96:Frank Clarke Fraser
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944:Vladimir Hachinski
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469:The Globe and Mail
285:Doctor of Medicine
279:degree in 1941, a
214:Medicine, genetics
176:Medical geneticist
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289:McGill University
277:Master of Science
273:Acadia University
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205:Scientific career
166:McGill University
158:Acadia University
127:December 17, 2014
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497:. Retrieved
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439:November 23,
437:. Retrieved
433:the original
417:. Retrieved
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398:. Retrieved
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293:World War II
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219:Institutions
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129:(2014-12-17)
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1442:2014 deaths
1437:1920 births
1416:Salim Yusuf
1339:Emily Stowe
1235:Vera Peters
1146:Maud Menten
1126:Marco Marra
1121:Tak Wah Mak
1111:John McCrae
999:David Hubel
769:Max Cynader
739:Bruce Chown
711:John Browne
621:Murray Barr
419:October 13,
400:October 13,
162:Nova Scotia
136:Nationality
62:introducing
1431:Categories
1357:James Till
1299:Hans Selye
1276:Ian Rusted
1271:Claude Roy
984:Jack Hirsh
792:John Dirks
777:Paul David
499:2018-03-28
475:2015-01-27
449:References
249:geneticist
172:Occupation
111:1920-03-29
70:April 2014
45:references
926:Jean Gray
916:Phil Gold
878:Terry Fox
754:May Cohen
291:. During
255:Biography
146:Education
631:John Bel
259:Born in
140:Canadian
99:OC, FRSC
528:at the
154:Jamaica
58:improve
211:Fields
190:Awards
47:, but
281:Ph.D.
242:
441:2011
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