240:(2022), not least because Epstein "was struggling with" cell propagation techniques. According to The Irish Times, Barr's initial impression was that "Epstein was throwing out the good cells" too soon, whereas her methods enabled the team to develop a sufficiently large cluster of cells for
247:
In 1964, working together, Barr and
Epstein discovered EBV. (The virus was named for the cell culture in which it was identified.) Prior to determining specifics about EBV, Epstein, Barr, and Achong published their preliminary research in
165:
Barr's role in the discovery of EBV, also called human herpesvirus 4, was instrumental, as she prepared the samples used for experimentation as well as characterized the morphological and biological characteristics of the virus.
197:
Barr began working as a research assistant in 1955, gaining laboratory skills. While at the London
National Institute for Medical Research she mastered cell propagation, specifically the technique called
236:"Barr was by then known for her superior laboratory skills," and her ability to grow cells under controlled conditions was "key to the research," according to Gregory J. Morgan, in
833:
271:, and was unable to obtain a research position there, she became a teacher of physics, biology, chemistry, and mathematics in various private high schools.
244:, "an expert in electron microscopy" who was Epstein's second research assistant, to obtain an image sufficient for Epstein to identify a new herpes virus.
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Barr married
Australian Stuart Balding, an industrial chemist, in 1965. They moved to Australia in 1966 and had two children, Kirsten and Sean Balding.
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893:
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888:
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Epstein, MA; Achong, BG; Barr, YM (1964). "Virus particles in cultured lymphoblasts from
Burkitt's lymphoma".
226:
774:
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438:
903:
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In 1963, Barr was the first of two research assistants employed by the
English pathologist and virologist
953:
287:, the oldest of Robert and Gertrude Barr's four children. Robert Barr was a banking manager. She died in
908:
898:
253:
385:
948:
553:"Morphological and Biological Studies on a Virus in Cultured Lymphoblasts from Burkitt's lymphoma"
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in humans, has been called "one of the 20th century's most significant scientific discoveries."
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877:
775:"Overlooked No More: Yvonne Barr, Who Helped Discover a Cancer-Causing Virus"
662:
526:
494:"Overlooked No More: Yvonne Barr, Who Helped Discover a Cancer-Causing Virus"
450:
439:"Overlooked No More: Yvonne Barr, Who Helped Discover a Cancer-Causing Virus"
178:
at
Banbridge Academy Secondary School and graduated in 1953 with honours in
759:
670:
653:
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Ostor, Andrew (2001). "Immortal Women: Essays in
Medical Eponyms Part II".
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390:
341:
Yvonne Barr's video greeting at the EBV 50th anniversary conference in 2014
304:
Yvonne Barr's video greeting at the EBV 50th anniversary conference in 2014
199:
568:
256:
researchers later confirmed the new virus as responsible for the type of
241:
834:"Who was the woman who discovered a virus that exists in 95% of humans"
803:
Clinical
Virology Manual, Fifth Edition: Chapter 28: Epstein-Barr Virus
412:
249:
191:
151:
202:. Using this technique, she studied the bacterium determined to cause
684:
Crawford, Dorothy H.; Rickinson, Alan; Johannessen, IngĂłlfur (2014).
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229:(NIH). They were based at the Bland-Sutton Institute of Pathology at
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Barr graduated from the
University of London in 1966 with a
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158:(EBV), which, because it identified a virus as a cause of
264:
210:, her work as a research assistant involved studying the
194:
and medical research laboratories in the UK and Canada.
550:
190:. Following her graduation Barr held several posts at
551:
Epstein, MA; Henle, G; Achong, BG; Barr, YM (1965).
413:"Barr, Yvonne M. (1932-) – People and organisations"
233:, and Epstein became her PhD research supervisor.
800:
737:
527:"Cancer virus discovery helped by delayed flight"
238:Cancer Virus Hunters; A History of Tumor Virology
150:; 11 March 1932 – 13 February 2016) was an Irish
875:
225:, who had received a research grant from the US
805:. Washington, DC: ASM Press. pp. 387–398.
857:
686:Cancer Virus: The Story of Epstein-Barr Virus
858:Chasty, Beth; Cardogan, Mike (July 2020).
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206:, also known as Hansen's disease. At the
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715:"Encyclopedia of Australian Science"
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894:Alumni of the University of London
832:Ansede, Manuel (21 October 2022).
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889:Alumni of Trinity College Dublin
801:Chen D, Yen-Lieberman B (2016).
773:Ricks, Delthia (21 March 2024).
635:James, D. Geraint (1 May 2009).
614:10.1097/00000478-200110000-00016
492:Ricks, Delthia (21 March 2024).
437:Ricks, Delthia (21 March 2024).
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924:20th-century British biologists
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525:McGrath, Paula (6 April 2014).
929:British emigrants to Australia
688:. OUP Oxford. pp. 29–30.
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291:, Australia at the age of 83.
1:
752:10.1016/S0140-6736(64)91524-7
309:
267:. When she married, moved to
227:National Institutes of Health
939:Irish emigrants to Australia
260:the team had been studying.
16:Irish Virologist (1932-2016)
7:
328:: "Barr was born in Eire".
10:
975:
811:10.1128/9781555819156.ch28
254:University of Pennsylvania
231:Middlesex Hospital, London
944:People from Carlow (town)
358:"Yvonne Balding Obituary"
131:
119:
109:
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71:
52:
30:
23:
919:British women biologists
47:, County Carlow, Ireland
223:Michael Anthony Epstein
138:Yvonne Margaret Balding
934:Australian virologists
386:"Yvonne Margaret Barr"
216:canine distemper virus
154:who co-discovered the
79:Trinity College Dublin
864:Life in the Fast Lane
569:10.1084/jem.121.5.761
208:University of Toronto
654:10.1093/qjmed/hcn167
602:Am. J. Surgical Path
170:Education and career
84:University of London
904:British virologists
954:Cancer researchers
780:The New York Times
637:"A chance meeting"
499:The New York Times
443:The New York Times
366:. 19 February 2016
156:Epstein–Barr virus
97:Epstein–Barr virus
909:Women virologists
899:Irish virologists
746:(7335): 702–703.
608:(10): 1226–1333.
283:, County Carlow,
279:Barr was born in
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56:13 February 2016
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41:11 March 1932
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176:Head Prefect
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58:(2016-02-13)
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959:2016 deaths
884:1932 births
843:14 February
720:27 December
422:11 February
242:Bert Achong
66:, Australia
25:Yvonne Barr
878:Categories
536:4 November
326:James 2009
310:References
250:The Lancet
192:veterinary
152:virologist
37:1932-03-11
663:1460-2725
451:0362-4331
370:19 August
289:Melbourne
269:Australia
174:Barr was
64:Melbourne
819:79328822
786:29 March
760:14107961
671:19318370
622:11688470
587:14278230
531:BBC News
505:22 March
212:pathogen
114:Virology
838:El Pais
578:2138004
397:9 March
363:The Age
285:Ireland
204:leprosy
180:zoology
817:
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740:Lancet
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456:4 July
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281:Carlow
188:Dublin
160:cancer
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110:Fields
45:Carlow
815:S2CID
417:Trove
258:tumor
182:from
845:2024
788:2024
756:PMID
722:2013
690:ISBN
667:PMID
659:ISSN
618:PMID
583:PMID
538:2015
507:2024
458:2024
447:ISSN
424:2019
399:2024
372:2016
147:Barr
53:Died
31:Born
807:doi
748:doi
649:doi
645:102
641:QJM
610:doi
573:PMC
565:doi
561:121
265:PhD
143:née
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