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Heart

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4538: 1287:. The left anterior descending artery supplies heart tissue and the front, outer side, and septum of the left ventricle. It does this by branching into smaller arteries—diagonal and septal branches. The left circumflex supplies the back and underneath of the left ventricle. The right coronary artery supplies the right atrium, right ventricle, and lower posterior sections of the left ventricle. The right coronary artery also supplies blood to the atrioventricular node (in about 90% of people) and the sinoatrial node (in about 60% of people). The right coronary artery runs in a groove at the back of the heart and the left anterior descending artery runs in a groove at the front. There is significant variation between people in the anatomy of the arteries that supply the heart The arteries divide at their furthest reaches into smaller branches that join at the edges of each arterial distribution. 2076:, the venae cavae, and other locations, including pulmonary vessels and the right side of the heart itself. Baroreceptors fire at a rate determined by how much they are stretched, which is influenced by blood pressure, level of physical activity, and the relative distribution of blood. With increased pressure and stretch, the rate of baroreceptor firing increases, and the cardiac centers decrease sympathetic stimulation and increase parasympathetic stimulation. As pressure and stretch decrease, the rate of baroreceptor firing decreases, and the cardiac centers increase sympathetic stimulation and decrease parasympathetic stimulation. There is a similar reflex, called the atrial reflex or 3446:(2nd century CE) knew blood vessels carried blood and identified venous (dark red) and arterial (brighter and thinner) blood, each with distinct and separate functions. Galen, noting the heart as the hottest organ in the body, concluded that it provided heat to the body. The heart did not pump blood around, the heart's motion sucked blood in during diastole and the blood moved by the pulsation of the arteries themselves. Galen believed the arterial blood was created by venous blood passing from the left ventricle to the right through 'pores' between the ventricles. Air from the lungs passed from the lungs via the pulmonary artery to the left side of the heart and created arterial blood. 2080:, associated with varying rates of blood flow to the atria. Increased venous return stretches the walls of the atria where specialized baroreceptors are located. However, as the atrial baroreceptors increase their rate of firing and as they stretch due to the increased blood pressure, the cardiac center responds by increasing sympathetic stimulation and inhibiting parasympathetic stimulation to increase heart rate. The opposite is also true. Chemoreceptors present in the carotid body or adjacent to the aorta in an aortic body respond to the blood's oxygen, carbon dioxide levels. Low oxygen or high carbon dioxide will stimulate firing of the receptors. 4394:, the heart is usually situated around the middle of the thorax. In terrestrial and arboreal snakes it is usually located nearer to the head; in aquatic species the heart is more centrally located. There is a heart with three chambers: two atria and one ventricle. The form and function of these hearts are different from mammalian hearts due to the fact that snakes have an elongated body, and thus are affected by different environmental factors. In particular, the snake's heart relative to the position in their body has been influenced greatly by gravity. Therefore, snakes that are larger in size tend to have a higher 1880: 3007:(ventricular repolarisation). As the heart cells contract, they create a current that travels through the heart. A downward deflection on the ECG implies cells are becoming more positive in charge ("depolarising") in the direction of that lead, whereas an upward inflection implies cells are becoming more negative ("repolarising") in the direction of the lead. This depends on the position of the lead, so if a wave of depolarising moved from left to right, a lead on the left would show a negative deflection, and a lead on the right would show a positive deflection. The ECG is a useful tool in detecting 845: 4694: 4733: 4709: 858: 2977: 4413:, the septum extends partway into the ventricle. This allows for some degree of separation between the de-oxygenated bloodstream destined for the lungs and the oxygenated stream that is delivered to the rest of the body. The absence of such a division in living amphibian species may be partly due to the amount of respiration that occurs through the skin; thus, the blood returned to the heart through the venae cavae is already partially oxygenated. As a result, there may be less need for a finer division between the two bloodstreams than in lungfish or other 3809: 3408: 9524: 3515: 1428: 4682: 4670: 1710: 1663: 2803: 2363: 1902: 524: 1535: 60: 4606: 1335: 4387:, meaning a circulatory system divided into arterial and venous parts. However, the heart itself is not completely separated into two sides. Instead, it is separated into three chambers—two atria and one ventricle. Blood returning from both the systemic circulation and the lungs is returned, and blood is pumped simultaneously into the systemic circulation and the lungs. The double system allows blood to circulate to and from the lungs which deliver oxygenated blood directly to the heart. 2152: 3765: 4745: 2126: 1093: 3750: 3785: 1945: 1231: 4464: 4721: 833: 4346: 1824: 1463:. Between the third and fourth week, the heart tube lengthens, and begins to fold to form an S-shape within the pericardium. This places the chambers and major vessels into the correct alignment for the developed heart. Further development will include the formation of the septa and the valves and the remodeling of the heart chambers. By the end of the fifth week, the septa are complete, and by the ninth week, the heart valves are complete. 587: 1055: 7490:"2016 European Guidelines on cardiovascular disease prevention in clinical practice: The Sixth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of 10 societies and by invited experts) Developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation (EACPR)" 740: 1112:. The cardiac muscle pattern is elegant and complex, as the muscle cells swirl and spiral around the chambers of the heart, with the outer muscles forming a figure 8 pattern around the atria and around the bases of the great vessels and the inner muscles, forming a figure 8 around the two ventricles and proceeding toward the apex. This complex swirling pattern allows the heart to pump blood more effectively. 3085:, which describes how much blood is ejected from the left and right ventricles after systole. Ejection fraction can then be obtained by dividing the volume ejected by the heart (stroke volume) by the volume of the filled heart (end-diastolic volume). Echocardiograms can also be conducted under circumstances when the body is more stressed, in order to examine for signs of lack of blood supply. This 6856:"ACC/AHA/ESC guidelines for the management of patients with supraventricular arrhythmias – executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Develop Guidelines for the Management of Patients With Supraventricular Arrhythmias)" 641: 2303:. Heart failure is frequently associated with weakness of the heart muscle in the ventricles (systolic heart failure), but can also be seen in patients with heart muscle that is strong but stiff (diastolic heart failure). The condition may affect the left ventricle (causing predominantly breathlessness), the right ventricle (causing predominantly swelling of the legs and an elevated 2783: 2186:, which include diseases of the heart, are the leading cause of death worldwide. The majority of cardiovascular disease is noncommunicable and related to lifestyle and other factors, becoming more prevalent with ageing. Heart disease is a major cause of death, accounting for an average of 30% of all deaths in 2008, globally. This rate varies from a lower 28% to a high 40% in 1520: 623: 595: 7554:"2014 ESC/EACTS Guidelines on myocardial revascularization: the Task Force on Myocardial Revascularization of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS). Developed with the special contribution of the European Association of Percutaneous Cardiovascular Interventions (EAPCI)" 1540: 1539: 1536: 2245:) or breathlessness during exercise or even at rest. The thin covering of an atherosclerotic plaque can rupture, exposing the fatty centre to the circulating blood. In this case a clot or thrombus can form, blocking the artery, and restricting blood flow to an area of heart muscle causing a myocardial infarction (a heart attack) or 1691:
As the pressure within the ventricles rises further, exceeding the pressure with the aorta and pulmonary arteries, the aortic and pulmonary valves open. Blood is ejected from the heart, causing the pressure within the ventricles to fall. Simultaneously, the atria refill as blood flows into the right atrium through the superior and
1541: 3337:. Implantable defibrillators are used to treat serious life-threatening rapid heart rhythms. These devices monitor the heart, and if dangerous heart racing is detected can automatically deliver a shock to restore the heart to a normal rhythm. Implantable defibrillators are most commonly used in patients with heart failure, 4621:, the circulatory system is not used to transport oxygen and so is much reduced, having no veins or arteries and consisting of two connected tubes. Oxygen travels by diffusion and there are five small muscular vessels that connect these vessels that contract at the front of the animals that can be thought of as "hearts". 4067:. There are also many references to the heart in the Christian Bible, including "Blessed are the pure in heart, for they will see God", "Above all else, guard your heart, for everything you do flows from it", "For where your treasure is, there your heart will be also", "For as a man thinks in his heart, so shall he be." 2345:, but some such as dilated cardiomyopathy may be caused by damage from toxins such as alcohol. Some cardiomyopathies such as hypertrophic cardiomopathy are linked to a higher risk of sudden cardiac death, particularly in athletes. Many cardiomyopathies can lead to heart failure in the later stages of the disease. 5398:"European guidelines on cardiovascular disease prevention in clinical practice: executive summary: Fourth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (Constituted by representatives of nine societies and by invited experts)" 4449:, at the base of the arterial trunks and there is some degree of mixing between the blood in each side of the heart, during a dive underwater; thus, only in birds and mammals are the two streams of blood—those to the pulmonary and systemic circulations—permanently kept entirely separate by a physical barrier. 1695:, and into the left atrium through the pulmonary veins. Finally, when the pressure within the ventricles falls below the pressure within the aorta and pulmonary arteries, the aortic and pulmonary valves close. The ventricles start to relax, the mitral and tricuspid valves open, and the cycle begins again. 6604:"2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC). Developed with the special contribution of the Heart Failure Association (HFA) of the ESC" 1538: 1679:. The atria and ventricles work in concert, so in systole when the ventricles are contracting, the atria are relaxed and collecting blood. When the ventricles are relaxed in diastole, the atria contract to pump blood to the ventricles. This coordination ensures blood is pumped efficiently to the body. 2914:
for a heart with insufficient blood supply. It is released 4–6 hours after injury and usually peaks at about 12–24 hours. Two tests of troponin are often taken—one at the time of initial presentation and another within 3–6 hours, with either a high level or a significant rise being diagnostic. A test
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Development of the human heart during the first eight weeks (top) and the formation of the heart chambers (bottom). In this figure, the blue and red colors represent blood inflow and outflow (not venous and arterial blood). Initially, all venous blood flows from the tail/atria to the ventricles/head,
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The papillary muscles extend from the walls of the heart to valves by cartilaginous connections called chordae tendinae. These muscles prevent the valves from falling too far back when they close. During the relaxation phase of the cardiac cycle, the papillary muscles are also relaxed and the tension
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for "estranged" (literally, "truncated of heart"). In Egyptian religion, the heart was the key to the afterlife. It was conceived as surviving death in the nether world, where it gave evidence for, or against, its possessor. The heart was therefore not removed from the body during mummification, and
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valves. After the ventricles have completed most of their filling, the atria contract, forcing further blood into the ventricles and priming the pump. Next, the ventricles start to contract. As the pressure rises within the cavities of the ventricles, the mitral and tricuspid valves are forced shut.
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Graham, I; Atar, D; Borch-Johnsen, K; Boysen, G; Burell, G; Cifkova, R; Dallongeville, J; De Backer, G; Ebrahim, S; Gjelsvik, B; Herrmann-Lingen, C; Hoes, A; Humphries, S; Knapton, M; Perk, J; Priori, SG; Pyorala, K; Reiner, Z; Ruilope, L; Sans-Menendez, S; Scholte op Reimer, W; Weissberg, P; Wood,
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As one of the vital organs, the heart was long identified as the center of the entire body, the seat of life, or emotion, or reason, will, intellect, purpose or the mind. The heart is an emblematic symbol in many religions, signifying "truth, conscience or moral courage in many religions—the temple
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are abnormal heart sounds which can be either related to disease or benign, and there are several kinds. There are normally two heart sounds, and abnormal heart sounds can either be extra sounds, or "murmurs" related to the flow of blood between the sounds. Murmurs are graded by volume, from 1 (the
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exist beneath each of the three layers of the heart. These networks collect into a main left and a main right trunk, which travel up the groove between the ventricles that exists on the heart's surface, receiving smaller vessels as they travel up. These vessels then travel into the atrioventricular
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to lubricate the surface of the heart. The part of the serous membrane attached to the fibrous membrane is called the parietal pericardium, while the part of the serous membrane attached to the heart is known as the visceral pericardium. The pericardium is present in order to lubricate its movement
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The heart evolved no less than 380 million years ago in fish. Fish have what is often described as a two-chambered heart, consisting of one atrium to receive blood and one ventricle to pump it. However, the fish heart has entry and exit compartments that may be called chambers, so it is also
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The ions move from areas where they are concentrated to where they are not. For this reason sodium moves into the cell from outside, and potassium moves from within the cell to outside the cell. Calcium also plays a critical role. Their influx through slow channels means that the sinoatrial cells
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The prepotential is due to a slow influx of sodium ions until the threshold is reached followed by a rapid depolarisation and repolarisation. The prepotential accounts for the membrane reaching threshold and initiates the spontaneous depolarisation and contraction of the cell; there is no resting
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Cardiac output (CO) is a measurement of the amount of blood pumped by each ventricle (stroke volume) in one minute. This is calculated by multiplying the stroke volume (SV) by the beats per minute of the heart rate (HR). So that: CO = SV x HR. The cardiac output is normalized to body size through
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and empties into the upper back part of the right atrium. The inferior vena cava drains the blood from below the diaphragm and empties into the back part of the atrium below the opening for the superior vena cava. Immediately above and to the middle of the opening of the inferior vena cava is the
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but not in more primitive vertebrates. In these animals, the muscles of the heart are relatively continuous, and the sinus venosus coordinates the beat, which passes in a wave through the remaining chambers. Since the sinus venosus is incorporated into the right atrium in amniotes, it is likely
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positioned upwards and tapering down to the apex. An adult heart has a mass of 250–350 grams (9–12 oz). The heart is often described as the size of a fist: 12 cm (5 in) in length, 8 cm (3.5 in) wide, and 6 cm (2.5 in) in thickness, although this description is
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Indigenous leaders from Alaska to Australia came together in 2020 to deliver a message to the world that humanity needs to shift from the mind to the heart, and let our heart be in charge of what we do. The message was made into a film, which highlighted that humanity must open their hearts to
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refers to the filling pressure of the atria at the end of diastole, when the ventricles are at their fullest. A main factor is how long it takes the ventricles to fill: if the ventricles contract more frequently, then there is less time to fill and the preload will be less. Preload can also be
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reinforces the thin walls of the right ventricle and plays a crucial role in cardiac conduction. It arises from the lower part of the interventricular septum and crosses the interior space of the right ventricle to connect with the inferior papillary muscle. The right ventricle tapers into the
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into the right ventricle. As the right ventricle contracts, the tricuspid valve closes and the blood is pumped into the pulmonary trunk through the pulmonary valve. The pulmonary trunk divides into pulmonary arteries and progressively smaller arteries throughout the lungs, until it reaches
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Bourier, Felix; Denis, Arnaud; Cheniti, Ghassen; Lam, Anna; Vlachos, Konstantinos; Takigawa, Masateru; Kitamura, Takeshi; Frontera, Antonio; Duchateau, Josselin; Pambrun, Thomas; Klotz, Nicolas; Derval, Nicolas; Sacher, Frédéric; Jais, Pierre; Haissaguerre, Michel (27 November 2018).
3439:(304–250 BCE) noted the heart as a pump, causing dilation of blood vessels, and noted that arteries and veins both radiate from the heart, becoming progressively smaller with distance, although he believed they were filled with air and not blood. He also discovered the heart valves. 2880:
quietest), to 6 (the loudest), and evaluated by their relationship to the heart sounds, position in the cardiac cycle, and additional features such as their radiation to other sites, changes with a person's position, the frequency of the sound as determined by the side of the
916:. This has three cusps which are not attached to any papillary muscles. When the ventricle relaxes blood flows back into the ventricle from the artery and this flow of blood fills the pocket-like valve, pressing against the cusps which close to seal the valve. The semilunar 4036:
restore balance to the world. Kumu Sabra Kauka, a Hawaiian studies educator and tradition bearer summed up the message of the film saying "Listen to your heart. Follow your path. May it be clear, and for the good of all." The film was led by Illarion Merculieff from the
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on the chordae tendineae is slight. As the heart chambers contract, so do the papillary muscles. This creates tension on the chordae tendineae, helping to hold the cusps of the atrioventricular valves in place and preventing them from being blown back into the atria.
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lies between the left atrium and left ventricle. It is also known as the bicuspid valve due to its having two cusps, an anterior and a posterior cusp. These cusps are also attached via chordae tendinae to two papillary muscles projecting from the ventricular wall.
4529:, presumably having been absorbed into the ventricles over the course of evolution. Similarly, while the sinus venosus is present as a vestigial structure in some reptiles and birds, it is otherwise absorbed into the right atrium and is no longer distinguishable. 6807:"2013 ESC guidelines on cardiac pacing and cardiac resynchronization therapy: the task force on cardiac pacing and resynchronization therapy of the European Society of Cardiology (ESC). Developed in collaboration with the European Heart Rhythm Association (EHRA)" 1526: 1385:
and travel to both the sinoatrial and atrioventricular nodes, as well as to the atria and ventricles. The ventricles are more richly innervated by sympathetic fibers than parasympathetic fibers. Sympathetic stimulation causes the release of the neurotransmitter
628: 598: 4402:), with a considerable gap near the pulmonary artery and aortic openings. In most reptilian species, there appears to be little, if any, mixing between the bloodstreams, so the aorta receives, essentially, only oxygenated blood. The exception to this rule is 597: 602: 601: 596: 629: 5397: 1398:
of the cardiac nerves. This shortens the repolarisation period, thus speeding the rate of depolarisation and contraction, which results in an increased heart rate. It opens chemical or ligand-gated sodium and calcium ion channels, allowing an influx of
813:. The interatrial septum separates the atria, and the interventricular septum separates the ventricles. The interventricular septum is much thicker than the interatrial septum since the ventricles need to generate greater pressure when they contract. 603: 2621:
of each heart cell. Because the beating of the heart depends on the proper movement of ions across the surface membrane, cardiac ion channelopathies form a major group of heart diseases. Cardiac ion channelopathies may explain some of the cases of
1919: 6688:"Guidelines on the management of valvular heart disease (version 2012): the Joint Task Force on the Management of Valvular Heart Disease of the European Society of Cardiology (ESC) and the European Association for Cardio-Thoracic Surgery (EACTS)" 3170:, during which narrowings can be expanded by passing small balloon-tipped wires into the coronary arteries, inflating the balloon to expand the narrowing, and sometimes leaving behind a metal scaffold known as a stent to keep the artery open. 2539:. Pericardial effusions often occur secondary to pericarditis, kidney failure, or tumours, and frequently do not cause any symptoms. However, large effusions or effusions which accumulate rapidly can compress the heart in a condition known as 6658: 4444:
show complete separation of the heart into two pumps for a total of four heart chambers; it is thought that the four-chambered heart of archosaurs evolved independently from that of mammals. In crocodilians, there is a small opening, the
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with the SA node. In teleosts, with their vestigial sinus venosus, the main centre of coordination is, instead, in the atrium. The rate of heartbeat varies enormously between different species, ranging from around 20 beats per minute in
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The cardiac cycle is the sequence of events in which the heart contracts and relaxes with every heartbeat. The period of time during which the ventricles contract, forcing blood out into the aorta and main pulmonary artery, is known as
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Narrowings of the coronary arteries (ischemic heart disease) are treated to relieve symptoms of chest pain caused by a partially narrowed artery (angina pectoris), to minimise heart muscle damage when an artery is completely occluded
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European Society of Cardiology (ESC); European Heart Rhythm Association (EHRA); Brignole, Michele; Auricchio, Angelo; Baron-Esquivias, Gonzalo; Bordachar, Pierre; Boriani, Giuseppe; Breithardt, Ole-A.; Cleland, John (August 2013).
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The hearts of beef, pork, and mutton can generally be interchanged in recipes. As heart is a hard-working muscle, it makes for "firm and rather dry" meat, so is generally slow-cooked. Another way of dealing with toughness is to
990:, into which it ejects blood when contracting. The pulmonary trunk branches into the left and right pulmonary arteries that carry the blood to each lung. The pulmonary valve lies between the right heart and the pulmonary trunk. 1636:, and ultimately capillaries. In the capillaries, oxygen and nutrients from blood are supplied to body cells for metabolism, and exchanged for carbon dioxide and waste products. Capillary blood, now deoxygenated, travels into 6514: 1474:
that previously acted as a valve closes the foramen ovale and establishes the typical cardiac circulation pattern. A depression in the surface of the right atrium remains where the foramen ovale was, called the fossa ovalis.
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groove, and receive a third vessel which drains the section of the left ventricle sitting on the diaphragm. The left vessel joins with this third vessel, and travels along the pulmonary artery and left atrium, ending in the
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near to the junction with the superior vena cava. The electrical signal generated by the sinoatrial node travels through the right atrium in a radial way that is not completely understood. It travels to the left atrium via
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sometimes described as three-chambered or four-chambered, depending on what is counted as a chamber. The atrium and ventricle are sometimes considered "true chambers", while the others are considered "accessory chambers".
1537: 4040:(Unangan) tribe. Merculieff has written that Unangan Elders referred to the heart as a "source of wisdom", "a deeper portal of profound interconnectedness and awareness that exists between humans and all living things". 3919:, which symbolized the ideal standard of behavior. If the scales balanced, it meant the heart's possessor had lived a just life and could enter the afterlife; if the heart was heavier, it would be devoured by the monster 3207:
Diseased heart valves that have become abnormally narrow or abnormally leaky may require surgery. This is traditionally performed as an open surgical procedure to replace the damaged heart valve with a tissue or metallic
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UhlĂ©n, Mathias; Fagerberg, Linn; Hallström, Björn M.; Lindskog, Cecilia; Oksvold, Per; Mardinoglu, Adil; Sivertsson, Åsa; Kampf, Caroline; Sjöstedt, Evelina (23 January 2015). "Tissue-based map of the human proteome".
2859:, S2, is the sound of the semilunar valves closing during ventricular diastole and is described as "dub". Each sound consists of two components, reflecting the slight difference in time as the two valves close. S2 may 2039:
can be 129 beats per minute (bpm) and this gradually decreases until maturity. An athlete's heart rate can be lower than 60 bpm. During exercise the rate can be 150 bpm with maximum rates reaching from 200 to 220 bpm.
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may also be required to treat arrhythmias. Pacemakers, comprising a small battery powered generator implanted under the skin and one or more leads that extend to the heart, are most commonly used to treat abnormally
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in the brainstem control the sympathetic and parasympathetic influences to the heart through the vagus nerve and sympathetic trunk. These cardiovascular centres receive input from a series of receptors including
3471:. In his manuscript, al-Nafis wrote that blood passes through the pulmonary circulation instead of moving from the right to the left ventricle as previously believed by Galen. His work was later translated into 2381: 2240:
the coronary arteries, and if severe may reduce blood flow to the heart. If a narrowing (or stenosis) is relatively minor then the patient may not experience any symptoms. Severe narrowings may cause chest pain
1470:. The foramen ovale allowed blood in the fetal heart to pass directly from the right atrium to the left atrium, allowing some blood to bypass the lungs. Within seconds after birth, a flap of tissue known as the 1216:
The pericardium is the sac that surrounds the heart. The tough outer surface of the pericardium is called the fibrous membrane. This is lined by a double inner membrane called the serous membrane that produces
1326:. The right vessel travels along the right atrium and the part of the right ventricle sitting on the diaphragm. It usually then travels in front of the ascending aorta and then ends in a brachiocephalic node. 1843:(also known as the sinus node or the SA node). Here an electrical signal is created that travels through the heart, causing the heart muscle to contract. The sinoatrial node is found in the upper part of the 6915:
Baumgartner, Helmut; Bonhoeffer, Philipp; De Groot, Natasja M. S.; de Haan, Fokko; Deanfield, John Erik; Galie, Nazzareno; Gatzoulis, Michael A.; Gohlke-Baerwolf, Christa; Kaemmerer, Harald (December 2010).
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Ampanozi, Garyfalia; Krinke, Eileen; Laberke, Patrick; Schweitzer, Wolf; Thali, Michael J.; Ebert, Lars C. (7 May 2018). "Comparing fist size to heart size is not a viable technique to assess cardiomegaly".
542: 4590:, a cavity between the organs. The heart in arthropods is typically a muscular tube that runs the length of the body, under the back and from the base of the head. Instead of blood the circulatory fluid is 2388:
Heart sounds of a 16 year old girl diagnosed with mitral valve prolapse and mitral regurgitation. Auscultating her heart, a systolic murmur and click is heard. Recorded with the stethoscope over the mitral
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Primitive fish have a four-chambered heart, but the chambers are arranged sequentially so that this primitive heart is quite unlike the four-chambered hearts of mammals and birds. The first chamber is the
3061:. An echocardiogram is an ultrasound of the heart used to measure the heart's function, assess for valve disease, and look for any abnormalities. Echocardiography can be conducted by a probe on the chest ( 3540:(1866–1927) was an important English physiologist who also studied the heart. Although they worked largely independently, their combined efforts and similar conclusions have been recognized in the name " 4513:
In the adult fish, the four chambers are not arranged in a straight row but instead form an S-shape, with the latter two chambers lying above the former two. This relatively simple pattern is found in
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Humans have known about the heart since ancient times, although its precise function and anatomy were not clearly understood. From the primarily religious views of earlier societies towards the heart,
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Vahanian, Alec; Alfieri, Ottavio; Andreotti, Felicita; Antunes, Manuel J.; BarĂłn-Esquivias, Gonzalo; Baumgartner, Helmut; Borger, Michael Andrew; Carrel, Thierry P.; De Bonis, Michele (October 2012).
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has improved the management of chronic heart failure, the disease continues to be an enormous medical and societal burden, with 30 to 40% of patients dying within a year of receiving the diagnosis.
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Ponikowski, Piotr; Voors, Adriaan A.; Anker, Stefan D.; Bueno, Héctor; Cleland, John G. F.; Coats, Andrew J. S.; Falk, Volkmar; Gonzålez-Juanatey, José Ramón; Harjola, Veli-Pekka (August 2016).
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Using surface electrodes on the body, it is possible to record the electrical activity of the heart. This tracing of the electrical signal is the electrocardiogram (ECG) or (EKG). An ECG is a
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Authors/Task Force Members; Piepoli, Massimo F.; Hoes, Arno W.; Agewall, Stefan; Albus, Christian; Brotons, Carlos; Catapano, Alberico L.; Cooney, Marie-Therese; CorrĂ , Ugo (September 2016).
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Blomström-Lundqvist, Carina; Scheinman, Melvin M.; Aliot, Etienne M.; Alpert, Joseph S.; Calkins, Hugh; Camm, A. John; Campbell, W. Barton; Haines, David E.; Kuck, Karl H. (14 October 2003).
4417:. Nonetheless, in at least some species of amphibian, the spongy nature of the ventricle does seem to maintain more of a separation between the bloodstreams. Also, the original valves of the 2543:, causing breathlessness and potentially fatal low blood pressure. Fluid can be removed from the pericardial space for diagnosis or to relieve tamponade using a syringe in a procedure called 3166:
In addition to using medications, narrowed heart arteries can be treated by expanding the narrowings or redirecting the flow of blood to bypass an obstruction. This may be performed using a
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also takes the metaphorical meanings of "mind", "intention", or "core", and is often translated as "heart-mind" as the ancient Chinese believed the heart was the center of human cognition.
4564: 2456:), this normal rhythm can be disrupted. Abnormal heart rhythms or arrhythmias may be asymptomatic or may cause palpitations, blackouts, or breathlessness. Some types of arrhythmia such as 2379: 540: 9794:
Schipp, R., von Boletzky, S., Jakobs, P. et al. A congenital malformation of the systemic heart complex inSepia officinalis L. (Cephalopoda). HelgolĂ€nder Meeresunters. 52, 29–40 (1998).
3363:), the mainstay of heart failure treatment is with medication. These include drugs to prevent fluid from accumulating in the lungs by increasing the amount of urine a patient produces ( 1760:. This states that the force of contraction is directly proportional to the initial length of muscle fiber, meaning a ventricle will contract more forcefully, the more it is stretched. 2596:), causing breathlessness and a lower rate of growth. More minor forms of congenital heart disease may remain undetected for many years and only reveal themselves in adult life (e.g., 1522: 2414:). Valvular heart disease may cause breathlessness, blackouts, or chest pain, but may be asymptomatic and only detected on a routine examination by hearing abnormal heart sounds or a 6506: 7552:
Kolh, Philippe; Windecker, Stephan; Alfonso, Fernando; Collet, Jean-Philippe; Cremer, Jochen; Falk, Volkmar; Filippatos, Gerasimos; Hamm, Christian; Head, Stuart J. (October 2014).
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A cross section of a three-chambered adult amphibian heart. Note the single ventricle. The purple regions represent areas where mixing of oxygenated and de-oxygenated blood occurs.
3224:, avoiding the need for a valve replacement. Heart valves can also be treated percutaneously, using techniques that share many similarities with percutaneous coronary intervention. 1482:
heart begins beating at around 22 days after conception (5 weeks after the last normal menstrual period, LMP). It starts to beat at a rate near to the mother's which is about 75–80
4294:
ranging from those of the smallest mice (12 mg) to the blue whale (600 kg). In vertebrates, the heart lies in the middle of the ventral part of the body, surrounded by a
1864:, tissue within the heart that the electrical signal cannot pass through, which forces the signal to pass through the atrioventricular node only. The signal then travels along the 1381:
and provides parasympathetic stimulation to a large number of organs in the thorax and abdomen, including the heart. The nerves from the sympathetic trunk emerge through the T1-T4
599: 2821: 2588:
Some congenital heart defects allow blood that is low in oxygen that would normally be returned to the lungs to instead be pumped back to the rest of the body. These are known as
6547: 3524: 624: 3386:
can be used to improve the heart's pumping efficiency. These devices are frequently combined with a defibrillator. In very severe cases of heart failure, a small pump called a
1486:(bpm). The embryonic heart rate then accelerates and reaches a peak rate of 165–185 bpm early in the early 7th week (early 9th week after the LMP). After 9 weeks (start of the 1729:
The average cardiac output, using an average stroke volume of about 70mL, is 5.25 L/min, with a normal range of 4.0–8.0 L/min. The stroke volume is normally measured using an
6750:
Kirchhof, Paulus; Benussi, Stefano; Kotecha, Dipak; Ahlsson, Anders; Atar, Dan; Casadei, Barbara; Castella, Manuel; Diener, Hans-Christoph; Heidbuchel, Hein (November 2016).
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or metaphysical heart was believed to be formed from one drop of blood from the child's mother's heart, taken at conception. To ancient Egyptians, the heart was the seat of
3309:
to prevent further heart rhythm disturbances. Whilst the majority of arrhythmias can be treated using minimally invasive catheter techniques, some arrhythmias (particularly
2875:
S4 is referred to as an atrial gallop and is produced by the sound of blood being forced into a stiff ventricle. The combined presence of S3 and S4 give a quadruple gallop.
1600:
returns deoxygenated blood from the myocardium to the right atrium. The blood collects in the right atrium. When the right atrium contracts, the blood is pumped through the
1020:
The left ventricle is much thicker as compared with the right, due to the greater force needed to pump blood to the entire body. Like the right ventricle, the left also has
576: 328:. Fish, in contrast, have two chambers, an atrium and a ventricle, while most reptiles have three chambers. In a healthy heart, blood flows one way through the heart due to 5809:
Lindskog, Cecilia; Linné, Jerker; Fagerberg, Linn; Hallström, Björn M.; Sundberg, Carl Johan; Lindholm, Malene; Huss, Mikael; Kampf, Caroline; Choi, Howard (25 June 2015).
1151:, the unique ability to initiate a cardiac action potential at a fixed rate—spreading the impulse rapidly from cell to cell to trigger the contraction of the entire heart. 805:
gives structure to the heart. It forms the atrioventricular septum, which separates the atria from the ventricles, and the fibrous rings, which serve as bases for the four
5396:
D; Yarnell, J; Zamorano, JL; Walma, E; Fitzgerald, T; Cooney, MT; Dudina, A; European Society of Cardiology (ESC) Committee for Practice Guidelines, (CPG) (October 2007).
4525:, the conus arteriosus is very small and can more accurately be described as part of the aorta rather than of the heart proper. The conus arteriosus is not present in any 2819: 403:, where it receives oxygen and gives off carbon dioxide. Oxygenated blood then returns to the left atrium, passes through the left ventricle and is pumped out through the 3600:
in 1964, using a chimpanzee heart, but the patient died within 2 hours. The first human to human heart transplantation was performed in 1967 by the South African surgeon
2863:
into two distinct sounds, either as a result of inspiration or different valvular or cardiac problems. Additional heart sounds may also be present and these give rise to
2637:(LQTS) - Mostly hereditary. On EKG can be observed as longer corrected QT interval (QTc). Characterized by fainting, sudden, life-threatening heart rhythm disturbances - 2000:
in the membrane of the sinoatrial cells. The potassium and calcium start to move out of and into the cell only once it has a sufficiently high charge, and so are called
4490:. From here, blood flows into the atrium and then to the powerful muscular ventricle where the main pumping action will take place. The fourth and final chamber is the 3655:
had surpassed infectious disease as the leading cause of death in the United States, and it is currently the leading cause of deaths worldwide. Since 1948, the ongoing
2418:. In the developed world, valvular heart disease is most commonly caused by degeneration secondary to old age, but may also be caused by infection of the heart valves ( 2406:
Healthy heart valves allow blood to flow easily in one direction, and prevent it from flowing in the other direction. A diseased heart valve may have a narrow opening (
3855:, is used in these meanings, as the seat of emotion, the mind, and referring to the anatomical organ. It is also connected in function and symbolism to the stomach. 8498: 1573:. The systemic circulation then transports oxygen to the body and returns carbon dioxide and relatively deoxygenated blood to the heart for transfer to the lungs. 958:, which is immediately above and to the middle of the opening of the inferior vena cava. In the wall of the right atrium is an oval-shaped depression known as the 5994: 3659:
has shed light on the effects of various influences on the heart, including diet, exercise, and common medications such as aspirin. Although the introduction of
2561:
Some people are born with hearts that are abnormal and these abnormalities are known as congenital heart defects. They may range from the relatively minor (e.g.
3620:, the first recipient of a donated heart, died 18 days after the operation while other patients did not survive for more than a few weeks. The American surgeon 2095:
can increase the heart rate. The levels of electrolytes including calcium, potassium, and sodium can also influence the speed and regularity of the heart rate;
2617:
can be categorized based on the organ system they affect. In the cardiovascular system, the electrical impulse required for each heart beat is provided by the
1139:. The pacemaker cells make up 1% of cells and form the conduction system of the heart. They are generally much smaller than the contractile cells and have few 3301:
in the leg to the heart to find the abnormal area of tissue that is causing the arrhythmia. The abnormal tissue can be intentionally damaged, or ablated, by
2650: 981:, ridges of cardiac muscle covered by endocardium. In addition to these muscular ridges, a band of cardiac muscle, also covered by endocardium, known as the 966:. Most of the internal surface of the right atrium is smooth, the depression of the fossa ovalis is medial, and the anterior surface has prominent ridges of 881:
The heart has four valves, which separate its chambers. One valve lies between each atrium and ventricle, and one valve rests at the exit of each ventricle.
9807: 2930:
Other blood tests are often taken to help understand a person's general health and risk factors that may contribute to heart disease. These often include a
2919:(BNP) can be used to evaluate for the presence of heart failure, and rises when there is increased demand on the left ventricle. These tests are considered 2820: 7952: 7626: 10585: 5679: 7041: 5163: 3616:, capturing the attention of both the medical profession and the world at large. However, long-term survival rates of patients were initially very low. 427:
and other substances are exchanged between blood vessels and cells, losing oxygen and gaining carbon dioxide—before being returned to the heart through
5507: 2592:
and are often more serious. Major congenital heart defects are often picked up in childhood, shortly after birth, or even before a child is born (e.g.
2483:
or tachyarrhythmia. These arrhythmias can take many forms and can originate from different structures within the heart—some arise from the atria (e.g.
1028:. The left ventricle pumps blood to the body through the aortic valve and into the aorta. Two small openings above the aortic valve carry blood to the 4132:
Animal hearts are widely consumed as food. As they are almost entirely muscle, they are high in protein. They are often included in dishes with other
3532:. Harvey's book completely describes the systemic circulation and the mechanical force of the heart, leading to an overhaul of the Galenic doctrines. 1921: 6117: 2988:
and involves the placement of ten leads on the body. This produces a "12 lead" ECG (three extra leads are calculated mathematically, and one lead is
7071:
Skinner JR, Winbo A, Abrams D, Vohra J, Wilde AA (January 2019). "Channelopathies That Lead to Sudden Cardiac Death: Clinical and Genetic Aspects".
5185:
de Lussanet, Marc H.E.; Osse, Jan W.M. (2012). "An ancestral axial twist explains the contralateral forebrain and the optic chiasm in vertebrates".
2065:, sensing the amount of oxygen and carbon dioxide in the blood and its pH. Through a series of reflexes these help regulate and sustain blood flow. 8877: 8554: 5913: 4537: 3482:
In Europe, the teachings of Galen continued to dominate the academic community and his doctrines were adopted as the official canon of the Church.
722:, the left lung is smaller than the right lung and has a cardiac notch in its border to accommodate the heart. The heart is cone-shaped, with its 449:
are the most common cause of death globally as of 2008, accounting for 30% of all human deaths. Of these more than three-quarters are a result of
2382: 1123:
of the conducting system. The muscle cells make up the bulk (99%) of cells in the atria and ventricles. These contractile cells are connected by
2426:
is a major cause of valvular heart disease, typically leading to mitral or aortic stenosis and caused by the body's immune system reacting to a
2410:), that restricts the flow of blood in the forward direction. A valve may otherwise be leaky, allowing blood to leak in the reverse direction ( 924:
and also is not attached to papillary muscles. This too has three cusps which close with the pressure of the blood flowing back from the aorta.
5705: 3173:
If the narrowings in coronary arteries are unsuitable for treatment with a percutaneous coronary intervention, open surgery may be required. A
543: 3565: 2855:
S1, is the sound created by the closing of the atrioventricular valves during ventricular contraction and is normally described as "lub". The
1222:
against other structures within the chest, to keep the heart's position stabilised within the chest, and to protect the heart from infection.
1085:
of the veins and arteries of the heart, and is joined to the myocardium with a thin layer of connective tissue. The endocardium, by secreting
3636:. As of March 2000, more than 55,000 heart transplantations have been performed worldwide. The first successful transplant of a heart from a 1781:. These agents can be a result of changes within the body, or be given as drugs as part of treatment for a medical disorder, or as a form of 1490:
stage) it starts to decelerate, slowing to around 145 (±25) bpm at birth. There is no difference in female and male heart rates before birth.
213: 3278:). In some arrhythmias such as atrial fibrillation which increase the risk of stroke, this risk can be reduced using anticoagulants such as 1632:
and into the aorta through the aortic valve for systemic circulation. The aorta is a large artery that branches into many smaller arteries,
884:
The valves between the atria and ventricles are called the atrioventricular valves. Between the right atrium and the right ventricle is the
4020:
system of belief. The most common form of human sacrifice practiced by the Aztecs was heart-extraction. The Aztec believed that the heart (
3463: 9716: 6310: 9854: 9747: 9685: 9651: 9263: 8659: 6284: 4984: 4950: 2569:). Common abnormalities include those that affect the heart muscle that separates the two side of the heart (a "hole in the heart", e.g. 2283:
Heart failure is defined as a condition in which the heart is unable to pump enough blood to meet the demands of the body. Patients with
10010: 8616: 8532: 4732: 3011:
and in detecting insufficient blood supply to the heart. Sometimes abnormalities are suspected, but not immediately visible on the ECG.
1756:
affected by a person's blood volume. The force of each contraction of the heart muscle is proportional to the preload, described as the
9294: 3254:) can be treated using antiarrhythmic drugs. These may work by manipulating the flow of electrolytes across the cell membrane (such as 3163:, lifestyle measures such as stopping smoking and weight loss, and treatment of risk factors such as high blood pressure and diabetes. 1777:
The strength of heart muscle contractions controls the stroke volume. This can be influenced positively or negatively by agents termed
6539: 3903:
was believed to be the center of intelligence and feeling, and needed in the afterlife. It was thought that the heart was examined by
10808: 10425: 4421:
have been replaced by a spiral valve that divides it into two parallel parts, thereby helping to keep the two bloodstreams separate.
3556: 1818: 1682:
At the beginning of the cardiac cycle, the ventricles are relaxing. As they do so, they are filled by blood passing through the open
1294:
is a large vein that drains into the right atrium, and receives most of the venous drainage of the heart. It receives blood from the
809:. The cardiac skeleton also provides an important boundary in the heart's electrical conduction system since collagen cannot conduct 7139: 8371: 3116:
Diseases affecting the heart can be treated by a variety of methods including lifestyle modification, drug treatment, and surgery.
11080: 9583: 7380: 6084: 10578: 10040: 6484: 5343: 4708: 3536:(1865–1944) was a German physiologist; among his many published works are detailed studies of this important heart relationship. 1628:, oxygenated blood is returned to the left atrium via the pulmonary veins. It is then pumped into the left ventricle through the 3700: 2679:- a genetic disorder characterized by an abnormal EKG and is one of the most common causes of sudden cardiac death in young men. 1268:. Blood flow through the coronary vessels occurs in peaks and troughs relating to the heart muscle's relaxation or contraction. 8201:
Miniati, Douglas N.; Robbins, Robert C. (2002). "Heart transplantation: a thirty-year perspective: A Thirty-Year Perspective".
3225: 2504: 3997:, or emotion, often disregarding the brain as contributing to those functions. The identification of the heart as the seat of 9940: 9921: 9902: 9883: 9848: 9775: 9741: 9710: 9679: 9645: 9472: 9397: 9367: 9336: 9288: 9257: 9107: 8861: 8836: 8639: 8610: 8577: 8526: 8479: 8454: 8404: 8347: 8322: 7468: 7340: 7295: 6803: 6431: 6180: 6155: 5889: 5735: 5625: 5490: 5379: 5157: 4978: 4944: 4917: 4875: 2656: 977:
The right atrium is connected to the right ventricle by the tricuspid valve. The walls of the right ventricle are lined with
9781: 9478: 9403: 9203:
Dobson, Geoffrey P (August 2003). "On Being the Right Size: Heart Design, Mitochondrial Efficiency and Lifespan Potential".
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which gained prominence from the mid sixteenth century. This tradition influenced the development of the medieval Christian
2927:
provides information about the heart's blood supply, but is used less frequently because it is less specific and sensitive.
731:
can have much larger hearts due to the effects of exercise on the heart muscle, similar to the response of skeletal muscle.
9873: 2307:), or both ventricles. Patients with heart failure are at higher risk of developing dangerous heart rhythm disturbances or 2236:—a build-up of fatty material along the inner walls of the arteries. These fatty deposits known as atherosclerotic plaques 1911: 4681: 2012:. When the membrane potential reaches approximately −60 mV, the potassium channels close and the process may begin again. 8776: 8495: 4693: 3930:
character for "heart", 濃, derives from a comparatively realistic depiction of a heart (indicating the heart chambers) in
1965:, a group of pacemaking cells found in the wall of the right atrium. Cells in the sinoatrial node do this by creating an 360:, the heart has an asymmetric orientation, almost always on the left side. According to one theory, this is caused by a 10571: 8802: 7527: 3167: 2593: 6237:
De Ponti, Roberto; et al. (2002). "Electroanatomic Analysis of Sinus Impulse Propagation in Normal Human Atria".
4744: 4586:). This blood slowly permeates the heart through many small one-way channels. The heart then pumps the blood into the 2786: 710:
The largest part of the heart is usually slightly offset to the left side of the chest (though occasionally it may be
10101: 9982: 9191: 9170: 9131: 9075: 9054: 9030: 8708: 8144: 6069: 5990: 3383: 2325:
Cardiomyopathies are diseases affecting the muscle of the heart. Some cause abnormal thickening of the heart muscle (
792: 695:. The upper part of the heart is located at the level of the third costal cartilage. The lower tip of the heart, the 2523:. This condition typically causes chest pain that may spread to the back, and is often caused by a viral infection ( 10096: 2627: 8966: 8238: 9815: 8916: 8265: 4093:, but while Ovid describes Cupid as wounding his victims with his arrows, it is not made explicit that it is the 3648:, recipient was David Bennett (57) this successfully extended his life until 8 March 2022 (1 month and 30 days). 2566: 2427: 2008:
open, allowing potassium to leave the cell. This causes the cell to have a negative resting charge and is called
1872:
through to the ventricles of the heart. In the ventricles the signal is carried by specialized tissue called the
8941: 7993: 7618: 8891: 7960: 7164: 5240:"Opposite asymmetries of face and trunk and of kissing and hugging, as predicted by the axial twist hypothesis" 4487: 4113: 3174: 3129: 3070: 2488: 2372: 2187: 1591:. Blood collects in the right and left atrium continuously. The superior vena cava drains blood from above the 1436:
The heart is the first functional organ to develop and starts to beat and pump blood at about three weeks into
1363: 1323: 384: 6198:"Electrical Conduction Between the Right Atrium and the Left Atrium via the Musculature of the Coronary Sinus" 5671: 5459: 4825:
cause the valves to open. The pressure difference between the blood in the atria and the ventricles does this.
3978:. In Sanskrit, it may mean both the anatomical object and "mind" or "soul", representing the seat of emotion. 932:
The right heart consists of two chambers, the right atrium and the right ventricle, separated by a valve, the
10721: 7858: 4834:
Depolarisation of the ventricles occurs concurrently, but is not significant enough to be detected on an ECG.
3637: 2338: 2001: 533: 9386:
Grimm, Kurt A.; Lamont, Leigh A.; Tranquilli, William J.; Greene, Stephen A.; Robertson, Sheilah A. (2015).
5515: 3423:
are considered to have been the primary seat of scientific understanding of the heart in the ancient world.
2503:), while others are caused by additional abnormal conduction tissue that has been present since birth (e.g. 1354:
also influence the force of heart contraction. Signals that travel along these nerves arise from two paired
11098: 10853: 10831: 4720: 4582:
have an open circulatory system. In this system, deoxygenated blood collects around the heart in cavities (
3585:
several months later. These structures form the anatomical basis of the electrocardiogram, whose inventor,
3541: 3325: 3245: 3144: 3062: 3058: 2996: 1155: 788: 3522:
A breakthrough in understanding the flow of blood through the heart and body came with the publication of
1370:
act to increase the heart rate. These nerves form a network of nerves that lies over the heart called the
11093: 10838: 10503: 10280: 10033: 5811:"The human cardiac and skeletal muscle proteomes defined by transcriptomics and antibody-based profiling" 4851: 3078: 2662: 2411: 2326: 2291:. Heart failure is the result of many diseases affecting the heart, but is most commonly associated with 1980:
When the sinoatrial cells are resting, they have a negative charge on their membranes. A rapid influx of
1448: 17: 9995:, BBC Radio 4 interdisciplinary discussion with David Wootton, Fay Bound Alberti & Jonathan Sawday ( 8724: 4631:, and one "systemic heart". The branchial hearts have two atria and one ventricle each, and pump to the 3143:), or to prevent a myocardial infarction from occurring. Medications to improve angina symptoms include 850:
The heart, showing valves, arteries and veins. The white arrows show the normal direction of blood flow.
10919: 3488: 3073:). A typical echocardiography report will include information about the width of the valves noting any 2519:
The sac which surrounds the heart, called the pericardium, can become inflamed in a condition known as
2334: 2017: 1790: 1404: 1351: 1078: 612: 2789:
showing the mitral valve (right), tricuspid and mitral valves (top left) and aortic valve (top right).
1988:
and occurs spontaneously. Once the cell has a sufficiently high charge, the sodium channels close and
1852:, such that the muscles of the left and right atria contract together. The signal then travels to the 11187: 11123: 11070: 10946: 10926: 10890: 10813: 10773: 10594: 10304: 9978:
Dissection review of the anatomy of the Human Heart including vessels, internal and external features
8203: 6752:"2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS" 4384: 4324: 4047:, there has been a long tradition of veneration of the heart, stemming from worship of the wounds of 3863: 3533: 3387: 3283: 2916: 2904:
Blood tests play an important role in the diagnosis and treatment of many cardiovascular conditions.
2889: 2570: 1640:
and veins that ultimately collect in the superior and inferior vena cavae, and into the right heart.
1272: 1271:
Heart tissue receives blood from two arteries which arise just above the aortic valve. These are the
108: 9966: 9493: 6030: 11182: 10941: 10931: 10821: 9893:
Longo, Dan; Fauci, Anthony; Kasper, Dennis; Hauser, Stephen; Jameson, J.; Loscalzo, Joseph (2011).
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Longo, Dan; Fauci, Anthony; Kasper, Dennis; Hauser, Stephen; Jameson, J.; Loscalzo, Joseph (2011).
5147: 4060: 3941: 3908: 3502: 3321:, whereby an electric shock is used to stun the heart out of an abnormal rhythm, may also be used. 3186: 2893: 2618: 2578: 2524: 2508: 2207: 1970: 1828: 1757: 1738: 1280: 1128: 664: 312:
In humans, other mammals, and birds, the heart is divided into four chambers: upper left and right
196: 3015:
can be used to provoke an abnormality or an ECG can be worn for a longer period such as a 24-hour
954:. A small amount of blood from the coronary circulation also drains into the right atrium via the 11128: 11060: 11005: 10906: 10826: 10710: 10688: 10284: 10197: 10165: 10153: 6387:"Resting pulse rate reference data for children, adolescents and adults, United States 1999–2008" 3945: 3625: 3407: 3356: 3302: 3255: 3241: 3125: 2713: 2556: 2496: 2492: 2423: 2304: 2292: 2227: 2087:, and even a person's emotional state can all affect the heart rate. High levels of the hormones 1857: 1806: 1733:
and can be influenced by the size of the heart, physical and mental condition of the individual,
799: 784: 760: 671:
surrounds the heart and attaches to the mediastinum. The back surface of the heart lies near the
660: 450: 10706: 9494:"Cardiovascular Dynamics in Crocodylus Porosus Breathing Air And During Voluntary Aerobic Dives" 4398:
due to gravitational change. The ventricle is incompletely separated into two-halves by a wall (
3390:
may be implanted which supplements the heart's own pumping ability. In the most severe cases, a
3108:. They are also useful for evaluating the aorta, the major blood vessel which leaves the heart. 2774:
is felt for any transmitted vibrations from the heart, and then listened to with a stethoscope.
2511:, in which the ventricles quiver rather than contract, and which if untreated is rapidly fatal. 2016:
have a prolonged "plateau" phase when they have a positive charge. A part of this is called the
11065: 11055: 10969: 10715: 10673: 10668: 10522: 10300: 10272: 10264: 10026: 9700: 9359: 9353: 7249: 7114: 6306: 6025: 3656: 3652: 3605: 3496:
was interpreted as a challenge to the authorities and he was subjected to a number of attacks.
3259: 3209: 3202: 2885: 2354: 2333:), some cause the heart muscle to become stiff and unable to fully relax between contractions ( 2330: 2296: 2199: 2183: 1879: 1395: 1311: 1299: 1284: 1105: 971: 756: 704: 446: 232: 220: 208: 144: 31: 9838: 9731: 9669: 9635: 9247: 6280: 4934: 4498:. The ventral aorta delivers blood to the gills where it is oxygenated and flows, through the 3640:
pig to a human in which the patient lived for a longer time, was performed January 7, 2022 in
2665:(BER) - common in younger and active people, especially men, because it is affected by higher 2287:
may experience breathlessness especially when lying flat, as well as ankle swelling, known as
1713:
The x-axis reflects time with a recording of the heart sounds. The y-axis represents pressure.
779:. Similarly, the left atrium and the left ventricle together are sometimes referred to as the 443:
temporarily increases the rate, but lowers it in the long term, and is good for heart health.
379:. These generate an electric current that causes the heart to contract, traveling through the 10914: 10445: 10350: 10318: 10192: 10111: 9977: 9551:"Dynamic Anatomical Study of Cardiac Shunting in Crocodiles Using High-Resolution Angioscopy" 8671: 8665: 8594: 8516: 8016: 7657:"The Beliefs, Myths, and Reality Surrounding the Word Hema (Blood) from Homer to the Present" 4179: 4056: 3624:
has been credited for his efforts to improve transplantation techniques, along with pioneers
3597: 3593: 3570: 3391: 3376: 3140: 2951: 2939: 2623: 2589: 2449: 2194:. Many other medical professionals are involved in treating diseases of the heart, including 2053: 1853: 1562: 1467: 1355: 1279:. The left main coronary artery splits shortly after leaving the aorta into two vessels, the 1276: 1037: 1010: 963: 396: 380: 333: 104: 9278: 3684: 3089:
involves either direct exercise, or where this is not possible, injection of a drug such as
2884:
by which they are heard, and site at which they are heard loudest. Murmurs may be caused by
1158:
in cardiac muscle cells. These are mostly associated with muscle contraction, and bind with
10663: 10646: 10547: 10440: 10376: 10296: 10268: 10215: 10116: 9099: 7815: 6990: 6918:"ESC Guidelines for the management of grown-up congenital heart disease (new version 2010)" 4700: 3719: 3458: 3178: 3105: 3081:) and information about the blood volumes at the end of systole and diastole, including an 2989: 2747: 2669:
levels, which cause increased potassium currents, which further causes an elevation of the
2597: 2562: 2536: 2084: 1927:
Heart sounds of a 16 year old girl immediately after running, with a heart rate of 186 BPM.
1849: 1766:, or how much pressure the heart must generate to eject blood at systole, is influenced by 1752: 1742: 1558: 1441: 1239: 1033: 959: 718:
is stronger and larger, since it pumps to all body parts. Because the heart is between the
408: 10563: 9705:. Stevens, E Don; Cech, Jr., Joseph J; Richards, Jeffrey G. Academic Press. p. 2315. 8162:"Recollections of the Early Years of Heart Transplantation and the Total Artificial Heart" 7506: 2976: 1860:, the boundary between the right atrium and the left ventricle. The septum is part of the 998:
The left heart has two chambers: the left atrium and the left ventricle, separated by the
857: 683:. The upper part of the heart is the attachment point for several large blood vessels—the 8: 11010: 10848: 10843: 10678: 10651: 10498: 10081: 9962:
Heart surgeon Bartley P Griffith talks about the unique transplant of pig heart to human.
9549:
Axelsson, Michael; Craig, Franklin; Löfman, Carl; Nilsson, Stefan; Crigg, Gordon (1996).
8420: 8239:"2022 News - IN MEMORIAM: David Bennett, Sr. | University of Maryland School of Medicine" 8216: 4595: 3986: 3645: 3310: 3221: 3086: 3012: 2971: 2725: 2693: 2638: 2582: 2472: 2457: 2258: 1789:. Inotropes that increase the force of contraction are "positive" inotropes, and include 1786: 1767: 1437: 1422: 1303: 1077:
The innermost layer of the heart is called the endocardium. It is made up of a lining of
772: 768: 482: 470: 136: 42: 9609: 7724: 7707: 6994: 3825: 3808: 3355:
As well as addressing the underlying cause for a patient's heart failure (most commonly
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type ventricular tachycardia, ventricular fibrillation and risk of sudden cardiac death.
1977:
into and out of the pacemaker cells. The action potential then spreads to nearby cells.
1143:
which gives them limited contractibility. Their function is similar in many respects to
11118: 10983: 10736: 10542: 10510: 10170: 10143: 10091: 9550: 9516: 9228: 9148: 8871: 8548: 8379: 8362: 8290: 8087: 7985: 7930: 7903:
Bondke Persson, A.; Persson, P. B. (2014). "Form and function in the vascular system".
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of the heart, giving the resting heart rate, is influenced by a number of factors. The
2029: 2005: 1954: 1692: 1675:, while the period during which the ventricles relax and refill with blood is known as 1610: 1592: 1585: 1581: 1550: 1501: 1452: 1307: 1295: 1021: 978: 948: 944: 896:
named the anterior, posterior, and septal muscles, after their relative positions. The
844: 657: 436: 392: 388: 361: 270: 140: 132: 124: 120: 80: 8829:
Nelson's Dictionary of Christianity: The Authoritative Resource on the Christian World
8030: 8011: 4468:
Blood flow through the fish heart: sinus venosus, atrium, ventricle, and outflow tract
3514: 3228:
is increasingly used for patients consider very high risk for open valve replacement.
1427: 477:, among others. Cardiovascular diseases do not frequently have symptoms but may cause 10754: 10726: 10552: 10480: 10430: 10276: 10175: 10160: 10148: 10076: 10071: 10004: 9936: 9917: 9898: 9879: 9844: 9771: 9737: 9706: 9675: 9641: 9575: 9468: 9443: 9393: 9363: 9332: 9284: 9253: 9220: 9216: 9187: 9166: 9127: 9103: 9071: 9068:
Classic Russian Cuisine: A Magnificent Selection of More Than 400 Traditional Recipes
9050: 9026: 8857: 8832: 8704: 8635: 8606: 8573: 8522: 8475: 8450: 8400: 8343: 8318: 8282: 8220: 8183: 8178: 8161: 8140: 8092: 8074: 8035: 7977: 7922: 7905: 7885: 7834: 7783: 7778: 7761: 7729: 7688: 7583: 7575: 7519: 7511: 7464: 7336: 7291: 7286:
Davidson, Sir Stanley; Colledge, Nicki R.; Walker, Brian R.; Ralston, Stuart (2010).
7231: 7213: 7088: 7053: 7014: 7006: 6947: 6939: 6885: 6877: 6836: 6828: 6781: 6773: 6717: 6709: 6654: 6642: 6634: 6427: 6397: 6367: 6254: 6250: 6219: 6176: 6151: 6065: 5895: 5885: 5850: 5832: 5783: 5775: 5621: 5563: 5555: 5486: 5422: 5375: 5271: 5212: 5153: 4974: 4940: 4913: 4871: 4543: 4163: 3887: 3633: 3629: 3412: 3317:
surgery, either at the time of other cardiac surgery or as a standalone procedure. A
3290: 3152: 3100:
and other forms of imaging can help evaluate the heart's size, evaluate for signs of
3082: 2896:
can be heard in cases of pericarditis where the inflamed membranes can rub together.
2868: 2852: 2644: 2581:). More complex syndromes are seen that affect more than one part of the heart (e.g. 2540: 2495:). Some tachyarrhythmias are caused by scarring within the heart (e.g. some forms of 2342: 2269:
can all increase the risk of developing atherosclerosis and coronary artery disease.
2165: 2077: 1719: 1709: 1456: 1418: 1367: 1359: 1347: 1218: 1124: 1120: 1014: 874: 775:. The right atrium and the right ventricle together are sometimes referred to as the 752: 502: 440: 341: 317: 9987: 9956: 9520: 9232: 8340:
Medicine in the Bible and the Talmud : selections from classical Jewish sources
7934: 7871: 7795: 7100: 6047: 5575: 2035:
The adult resting heart rate ranges from 60 to 100 bpm. The resting heart rate of a
11103: 10698: 10314: 10210: 10180: 9565: 9508: 9433: 9212: 9143: 9087: 8294: 8274: 8212: 8173: 8082: 8070: 8066: 8025: 7989: 7969: 7914: 7875: 7867: 7824: 7773: 7719: 7678: 7668: 7565: 7501: 7456: 7221: 7203: 7080: 7026: 6998: 6929: 6867: 6818: 6763: 6699: 6626: 6618: 6357: 6266: 6246: 6209: 6035: 5840: 5822: 5767: 5727: 5547: 5412: 5261: 5251: 5224: 5204: 4499: 4491: 4418: 4246: 4223: 4183: 4154: 3927: 3617: 3586: 3497: 3483: 3251: 3237: 3101: 3042: 2931: 2759: 2676: 2634: 2308: 2288: 2025: 1966: 1861: 1662: 1483: 1382: 967: 913: 893: 889: 862: 802: 680: 672: 466: 387:. In humans, deoxygenated blood enters the heart through the right atrium from the 156: 100: 9092: 7829: 7810: 6016:
DuBose, T. J.; Cunyus, J. A.; Johnson, L. (1990). "Embryonic Heart Rate and Age".
5795: 5551: 2673:
on the EKG. In very rare cases, it can lead to ventricular fibrillation and death.
1005:
The left atrium receives oxygenated blood back from the lungs via one of the four
10953: 10683: 10460: 10455: 10435: 10308: 10292: 10288: 10086: 9765: 9462: 9387: 8502: 8397:
Middle Egyptian : an introduction to the language and culture of hieroglyphs
8375: 8054: 7458: 6386: 6088: 4968: 4628: 4548: 4518: 4507: 4458: 4213: 4198: 4191: 4137: 3952: 3821: 3775: 3764: 3613: 3582: 3548: 3537: 3435:
noted blood circulating cyclically from the body through the heart to the lungs.
3213: 3034: 3028: 2754:
near the wrist, in order to assess for the rhythm and strength of the pulse. The
2709: 2689: 2614: 2574: 2528: 2445: 2246: 2233: 2211: 2169: 2157: 2092: 1962: 1873: 1869: 1840: 1687: 1601: 1314:
drain the front of the right ventricle and drain directly into the right atrium.
1253: 1148: 987: 933: 909: 885: 866: 764: 700: 692: 486: 376: 372: 282: 254: 201: 96: 8725:"'Listen to your heart': Indigenous elders channel tough love in Earth Day film" 4907: 2565:, arguably a variant of normal) to serious life-threatening abnormalities (e.g. 2479:). In other arrhythmias the heart may beat abnormally rapidly, referred to as a 549:
Sounds of a healthy 16-year-old child's heart beating normally, as heard with a
11177: 11113: 11038: 11030: 10624: 10611: 10417: 10358: 10340: 10254: 10138: 8263:
Neubauer, Stefan (15 March 2007). "The Failing Heart – An Engine Out of Fuel".
8012:"Why Does the Heart Beat?: The Discovery of the Electrical System of the Heart" 7973: 6934: 6917: 6039: 5417: 4395: 4257: 4146: 4121: 3935: 3795: 3756: 3621: 3581:
to look for similar structures in the heart, leading to their discovery of the
3529: 3506:(1553) that blood flows from one side of the heart to the other via the lungs. 3420: 3338: 3329: 3298: 3133: 3037:
methods can be used to assess the anatomy and function of the heart, including
3016: 2812: 2755: 2734:
The cardiac examination includes inspection, feeling the chest with the hands (
2701: 2532: 2484: 2320: 2300: 2250: 2100: 2009: 1985: 1730: 1704: 1597: 1566: 1387: 1371: 1291: 1136: 1101: 1049: 1025: 1006: 982: 955: 908:
Two additional semilunar valves sit at the exit of each of the ventricles. The
748: 506: 313: 286: 128: 59: 9961: 7290:(21st ed.). Edinburgh: Churchill Livingstone/Elsevier. pp. 522–536. 7084: 6823: 6806: 6768: 6751: 6214: 6197: 5827: 5282: 3289:
If medications fail to control an arrhythmia, another treatment option may be
2946:
is often required to ensure that the right level of anticoagulation is given.
939:
The right atrium receives blood almost continuously from the body's two major
838:
With the atria and major vessels removed, all four valves are clearly visible.
11171: 10731: 10641: 10634: 10619: 10450: 9972: 9447: 9042: 8078: 7579: 7515: 7217: 7140:"Catecholaminergic polymorphic ventricular tachycardia: MedlinePlus Genetics" 7057: 7010: 6943: 6881: 6832: 6777: 6713: 6638: 5899: 5836: 5779: 5559: 5216: 5208: 4912:. Wolters Kluwel Health/Lippincott Williams & Wilkins. pp. 127–173. 4646:
have a central "heart", which is a vesicle formed from the thickening of the
4643: 4479: 4340: 4336: 4253: 4079: 3859: 3660: 3552: 3476: 3372: 3350: 3318: 3189:) is used to redirect blood from a point before the narrowing (typically the 3182: 2947: 2864: 2751: 2609: 2467:
Some arrhythmias cause the heart to beat abnormally slowly, referred to as a
2284: 2278: 2062: 1865: 1798: 1723: 1649: 1471: 1460: 1391: 1334: 1191: 1131:
from the pacemaker cells. The intercalated discs allow the cells to act as a
1116: 633: 514: 225: 184: 9992: 9840:
Comparative Animal Physiology, Environmental and Metabolic Animal Physiology
7487: 7208: 6978: 5771: 4605: 3177:
can be performed, whereby a blood vessel from another part of the body (the
3019:
if a suspected rhythm abnormality is not present at the time of assessment.
2232:
Coronary artery disease, also known as ischemic heart disease, is caused by
11145: 11135: 11108: 10997: 10988: 10785: 10759: 10366: 10362: 10354: 10260: 9224: 8750: 8286: 8224: 8187: 8110: 8096: 8039: 7981: 7926: 7889: 7838: 7787: 7733: 7692: 7587: 7570: 7553: 7523: 7489: 7235: 7092: 7018: 6951: 6889: 6840: 6785: 6721: 6704: 6687: 6646: 6401: 6371: 6258: 5854: 5787: 5567: 5426: 5275: 4651: 4563: 4483: 4117: 4071: 4048: 4002: 3848: 3680: 3676: 3664: 3578: 3574: 3560: 3468: 3436: 3368: 3360: 3314: 3306: 3294: 3271: 3217: 3148: 3097: 2985: 2876: 2848: 2792: 2767: 2743: 2739: 2729: 2666: 2520: 2453: 2419: 2415: 2191: 2173: 2140: 2132: 2073: 2069: 2058: 2049: 1997: 1958: 1844: 1836: 1782: 1683: 1629: 1614: 1466:
Before the fifth week, there is an opening in the fetal heart known as the
1265: 1135:
and enable the contractions that pump blood through the heart and into the
1029: 999: 917: 897: 870: 822: 711: 490: 266: 75: 9579: 9570: 9438: 9421: 7673: 7594: 6223: 4967:
Reed, C. Roebuck; Brainerd, Lee Wherry; Lee, Rodney; Kaplan, Inc. (2008).
4547:
extends horizontally across the body, interlinked with the diamond-shaped
2444:
While in the healthy heart, waves of electrical impulses originate in the
2032:
of the cardiac muscle, and separate from the protein to allow relaxation.
1017:. The left atrium is connected to the left ventricle by the mitral valve. 675:, and the front surface known as the sternocostal surface sits behind the 11150: 11140: 10868: 10863: 10858: 10769: 10490: 10472: 10407: 10399: 10346: 10250: 10240: 10187: 8278: 6385:
Ostchega, Y; Porter, K. S.; Hughes, J; Dillon, C. F.; Nwankwo, T (2011).
6362: 6345: 5884:. Nielsen, Mark T. (Mark Thomas) (11th ed.). Hoboken, NJ: J. Wiley. 4655: 4602:
as the oxygen transporter. Haemoglobin is only used by a few arthropods.
4599: 4556: 4552: 4320: 4295: 4102: 4098: 4044: 3931: 3791: 3555:
were discovered as early as the 19th century, their specific role in the
3493: 3432: 3367:), and drugs that attempt to preserve the pumping function of the heart ( 3334: 3046: 3000: 2959: 2881: 2828: 2480: 2476: 2468: 2266: 2203: 2151: 2104: 2088: 1974: 1606: 1588: 1343: 1211: 1167: 1092: 1086: 1082: 1074:. These are surrounded by a double-membraned sac called the pericardium. 1063: 810: 806: 776: 684: 668: 653: 550: 498: 494: 420: 357: 353: 337: 329: 321: 306: 160: 5641: 5639: 5637: 5587: 5585: 4852:
OpenStax College, Anatomy & Physiology. OpenStax CNX. 30 July 2014.
4650:
and contracts to pump blood. This suggests a presence of it in the last
4399: 4231:, barbecued beef hearts are grilled after being tenderized through long 4190:
for chicken. Many recipes combined them with other giblets, such as the
4024:) was both the seat of the individual and a fragment of the Sun's heat ( 2125: 1089:, may also play a role in regulating the contraction of the myocardium. 767:. There is an ear-shaped structure in the upper right atrium called the 320:. Commonly, the right atrium and ventricle are referred together as the 11088: 10873: 10763: 10746: 10629: 10515: 10330: 10018: 9512: 7918: 6853: 6630: 5455: 5301: 5299: 5297: 5256: 4932: 4624: 4610: 4591: 4433: 4299: 4291: 4232: 4226: 4209: 4064: 3263: 3090: 3038: 2839: 2697: 2439: 2398: 2021: 1944: 1936: 1893: 1794: 1554: 1071: 1067: 780: 755:, the discharging chambers. The atria open into the ventricles via the 719: 715: 562: 510: 478: 462: 368: 349: 345: 325: 8572:(1st ed.). Brookline, Mass.: Paradigm Publications. p. 260. 7762:"Discovery of the cardiovascular system: from Galen to William Harvey" 5456:"Gray's Anatomy of the Human Body – 6. Surface Markings of the Thorax" 5311: 4583: 3771: 3382:
In some patients with heart failure, a specialised pacemaker known as
3151:, and calcium channel blockers, while preventative treatments include 2923:
because they are highly specific for cardiac disease. Testing for the
763:. This distinction is visible also on the surface of the heart as the 517:, although many specialties of medicine may be involved in treatment. 11020: 10791: 10658: 9795: 8655: 7854:"Ibn al-Nafis, the pulmonary circulation, and the Islamic Golden Age" 6622: 5634: 5597: 5582: 4776:
Arteries that contain deoxygenated blood, from the heart to the lungs
4639: 4618: 4575: 4568: 4429: 4403: 4376: 4166: 4140: 3990: 3982:
may be a cognate of the word for heart in Greek, Latin, and English.
3883: 3829: 3812: 3749: 3641: 3609: 3427:
considered the heart to be the organ responsible for creating blood;
3424: 3066: 3008: 2920: 2911: 2750:), joints and other areas. A person's pulse is taken, usually at the 2735: 2630:. Long QT syndrome is the most common form of cardiac channelopathy. 2215: 2195: 2096: 1993: 1984:
ions causes the membrane's charge to become positive; this is called
1823: 1805:. "Negative" inotropes decrease the force of contraction and include 1778: 1763: 1746: 1633: 1618: 1570: 1378: 1234:
Arterial supply to the heart (red), with other areas labelled (blue).
1140: 1132: 1058:
Layers of the heart wall, including visceral and parietal pericardium
951: 727:
disputed, as the heart is likely to be slightly larger. Well-trained
416: 9931:
Nicki R. Colledge; Brian R. Walker; Stuart H. Ralston, eds. (2010).
9021:
Abdennour, Samia (2010) "Firakh mahshiya wi mihammara", recipe 117,
7440: 7438: 7436: 7434: 7354: 7352: 7311: 7309: 7307: 7192:"Early Repolarization Syndrome: Diagnostic and Therapeutic Approach" 7002: 6914: 6325: 6094: 5949: 5947: 5294: 4996: 4994: 4463: 3784: 1565:
to and from the lungs. Blood in the pulmonary circulation exchanges
1244:
Heart tissue, like all cells in the body, needs to be supplied with
1230: 832: 11048: 10779: 9613: 8852:
Murray, Tom Devonshire Jones; Linda Murray; Peter (2013). "Heart".
6150:(7. ed.). London: Elsevier Health Sciences. pp. 912–922. 4865: 4587: 4503: 4414: 4410: 4345: 4187: 4157: 4097:
that is wounded. The familiar iconography of Cupid shooting little
3833: 3364: 3279: 3275: 3074: 2907: 2860: 2535:). Fluid can build up within the pericardial sac, referred to as a 2407: 2262: 2237: 2136: 1802: 1771: 1676: 1657: 1249: 1171: 1109: 1100:
The middle layer of the heart wall is the myocardium, which is the
1096:
The swirling pattern of myocardium helps the heart pump effectively
962:, which is a remnant of an opening in the fetal heart known as the 743:
Heart being dissected showing right and left ventricles, from above
474: 424: 412: 301:
and is located between the lungs, in the middle compartment of the
278: 8917:"Bible Gateway passage: Proverbs 4:23 - New International Version" 5199: 4908:
Moore, Keith L.; Dalley, Arthur F.; Agur, Anne M. R. (2009). "1".
2871:, S3 usually indicates an increase in ventricular blood volume. A 2139:. A number of diseases can be detected primarily by listening for 1350:. These nerves act to influence, but not control, the heart rate. 1054: 739: 238: 11043: 8942:"Bible Gateway passage: Matthew 6:21 - New International Version" 7431: 7419: 7349: 7304: 7267: 6958: 6896: 5971: 5944: 5932: 5861: 5651: 4991: 4579: 4526: 4522: 4380: 4316: 4306: 4150: 3998: 3975: 3960: 3879: 3875: 3589:, was awarded the Nobel Prize in Medicine or Physiology in 1924. 3270:), or modify the autonomic nervous system's effect on the heart ( 3267: 3156: 3050: 2935: 2892:, or may be heard in normal hearts. A different type of sound, a 2670: 2254: 2036: 1989: 1672: 1653: 1377:
The vagus nerve is a long, wandering nerve that emerges from the
728: 676: 580: 458: 38: 37:"Cardiac" redirects here. For the computer programming tool, see 8892:"Bible Gateway passage: Matthew 5:8 - New International Version" 8342:(Augm. ed.). Hoboken, NJ: KTAV Pub. House. pp. 87–96. 7457:
Armstrong, William F.; Ryan, Thomas; Feigenbaum, Harvey (2010).
6728: 6452: 6440: 6426:(11th ed.). Philadelphia: W.B. Saunders. pp. 116–122. 4239:
recipe for "mock goose" is actually braised stuffed beef heart.
2573:). Other defects include those affecting the heart valves (e.g. 1774:) or contraction or relaxation of the peripheral blood vessels. 1459:
form here that fuse to form a primitive heart tube known as the
1081:
and covers heart chambers and valves. It is continuous with the
395:
and passes to the right ventricle. From here, it is pumped into
10883: 10878: 9914:
Gray's anatomy : the anatomical basis of clinical practice
9331:. Philadelphia: Holt-Saunders International. pp. 437–442. 8967:"Bible Gateway passage: Proverbs 23:7 - New King James Version" 8474:. Berkeley: Society for the Study of Early China p. 176. 8399:(3rd ed.). Cambridge University Press. pp. 453, 465. 6685: 5808: 5756: 5536: 4884: 4441: 4287: 4284: 4028:). To this day, the Nahua consider the Sun to be a heart-soul ( 3994: 3956: 3904: 3841: 3837: 3160: 3004: 2461: 2242: 1981: 1637: 1479: 1400: 1318: 1257: 1256:. This is achieved by the coronary circulation, which includes 1245: 1163: 1144: 703:) between the junction of the fourth and fifth ribs near their 645: 454: 428: 302: 274: 258: 87: 8521:(3rd ed.). Boulder, Colo.: Blue Poppy Press. p. 47. 7407: 6562: 4482:, which collects deoxygenated blood from the body through the 485:. Diagnosis of heart disease is often done by the taking of a 30:
This article is about the internal organ. For other uses, see
11015: 10372: 9283:. Berlin, Heidelberg: Springer Berlin Heidelberg. p. 3. 8777:"Out of the Head, Into the Heart: The Way of the Human Being" 8683: 7811:"Pulmonary Arterial Hypertension: Yesterday, Today, Tomorrow" 7395: 7285: 6749: 6574: 5959: 5920: 5394: 4847: 4803:
Veins containing oxygenated blood from the lungs to the heart
4647: 4391: 4245:
heart is stewed, poached, braised, or made into sausage. The
4175: 4133: 4086: 4075: 4037: 4017: 4010: 4006: 3920: 3472: 3443: 3428: 3190: 2955: 2924: 2771: 2299:, or high blood pressure. Less common causes include various 1876:
which then transmit the electric charge to the heart muscle.
1596:
opening of the thin-walled coronary sinus. Additionally, the
1487: 1183: 1179: 1159: 921: 688: 640: 404: 294: 262: 172: 151: 92: 10003: 9935:(21st ed.). Edinburgh: Churchill Livingstone/Elsevier. 8449:. Chicago: The University of Chicago Press. pp. 35–38. 5336:"Cardiovascular diseases (CVDs) Fact sheet N°317 March 2013" 3431:
considered the heart as the source of circulating blood and
2577:), or the main blood vessels that lead from the heart (e.g. 1306:(draining the bottom of the left and right ventricles), and 513:. Specialists who focus on diseases of the heart are called 10593: 9912:
Susan Standring; Neil R. Borley; et al., eds. (2008).
9702:
Encyclopedia of Fish Physiology: From Genome to Environment
9385: 4966: 4632: 4506:, the ventral aorta has divided in two; one half forms the 4437: 4242: 4219: 4090: 3916: 3449:
These ideas went unchallenged for almost a thousand years.
2782: 2337:) and some make the heart prone to abnormal heart rhythms ( 1440:. This early start is crucial for subsequent embryonic and 1261: 1199: 1195: 1187: 1175: 940: 699:, lies to the left of the sternum (8 to 9 cm from the 586: 432: 400: 298: 290: 115: 9548: 9464:
Clinical Anatomy and Physiology for Veterinary Technicians
8634:(repr ed.). Delhi: Motilal Banarsidass. p. 287. 7708:"The "Modern" View of Heart Failure: How Did We Get Here?" 7551: 6384: 3951:"spirit, consciousness". The heart is associated with the 1511: 575: 8605:, Delhi: Motilal Banarsidass Publishers, pp. 71–83, 6601: 6346:"Ca exchange with troponin C and cardiac muscle dynamics" 4153:, and are often grilled on skewers; examples of this are 3054: 2329:), some cause the heart to abnormally expand and weaken ( 1856:. This is found at the bottom of the right atrium in the 1770:. It can be influenced by narrowing of the heart valves ( 1734: 9957:
Transplantation of pig heart to human. BBC, 11 Jan 2022.
8055:"A Brief History of Cross-Species Organ Transplantation" 7165:"Progressive familial heart block: MedlinePlus Genetics" 6175:(Third ed.). Oxford University Press. p. 266. 4970:
CSET : California Subject Examinations for Teachers
3915:
ceremony. If the heart weighed more than the feather of
2135:
of the heart, and is one of the most iconic symbols for
2020:. Calcium ions also combine with the regulatory protein 1617:
for oxygen. This happens through the passive process of
888:. The tricuspid valve has three cusps, which connect to 771:, or auricle, and another in the upper left atrium, the 10014:. Vol. 13 (11th ed.). 1911. pp. 129–134. 9276: 8854:
The Oxford dictionary of christian art and architecture
8803:"The Indigenous Art of Following Wisdom from the Heart" 7070: 5728:"The human proteome in heart – The Human Protein Atlas" 5374:(18 ed.). McGraw-Hill Professional. p. 1811. 5152:. OpenStax College, Rice University. pp. 787–846. 4494:, which contains several valves and sends blood to the 1992:
ions then begin to enter the cell, shortly after which
9764:
Solomon, Eldra; Berg, Linda; Martin, Diana W. (2010).
8632:
A Sanskrit reader : text and vocabulary and notes
7654: 7188: 6116:
Berry, William; McKenzie, Catherine (1 January 2010).
5369: 3461:
and pulmonary circulation systems can be found in the
1580:
collects deoxygenated blood from two large veins, the
1557:
throughout the body. This circulation consists of the
783:. The ventricles are separated from each other by the 9205:
Clinical and Experimental Pharmacology and Physiology
8111:"The operation that took medicine into the media age" 7902: 4812:
Veins that drain blood from the cardiac tissue itself
2651:
Catecholaminergic polymorphic ventricular tachycardia
2004:. Shortly after this, the calcium channels close and 1366:
acts to decrease the heart rate, and nerves from the
1298:(receiving the left atrium and both ventricles), the 1062:
The heart wall is made up of three layers: the inner
1013:. Like the right atrium, the left atrium is lined by 590:
Computer-generated animation of a beating human heart
9086: 8603:
Essays in Indian Philosophy, Religion and Literature
4933:
Starr, Cecie; Evers, Christine; Starr, Lisa (2009).
2942:
that may reveal any disturbances in electrolytes. A
2253:, a sudden and utter loss of output from the heart. 2083:
Exercise and fitness levels, age, body temperature,
344:. The wall of the heart is made up of three layers: 9542: 9485: 9327:Romer, Alfred Sherwood; Parsons, Thomas S. (1977). 9245: 8856:(Second ed.). Corby: Oxford University Press. 8690:("The Use of the Parts of the Human Body"), book 6. 6015: 5669: 4973:(3rd ed.). New York: Kaplan Pub. p. 154. 4009:, who also located the seat of the passions in the 3974:, found in the oldest surviving Sanskrit text, the 3486:questioned some of Galen's beliefs of the heart in 2068:Baroreceptors are stretch receptors located in the 1839:, is established by the heart's own pacemaker, the 9911: 9878:(12th ed.). Philadelphia: Saunders/Elsevier. 9698: 9091: 9023:Egyptian Cooking: And Other Middle Eastern Recipes 8518:Statements of fact in traditional Chinese medicine 7330: 5977: 5953: 5938: 5867: 5657: 5645: 5603: 5591: 5000: 2995:There are five prominent features on the ECG: the 2190:. Doctors that specialise in the heart are called 297:, the heart is approximately the size of a closed 9871: 9763: 9663: 9661: 9090:; Becker, Marion Rombauer; Becker, Ethan (1975). 6458: 6446: 6331: 6100: 5317: 5305: 5288: 4890: 4283:The size of the heart varies among the different 2746:that may be visible on a person's hands (such as 2341:). These conditions are often genetic and can be 1545:Video explanation of blood flow through the heart 336:. The heart is enclosed in a protective sac, the 11169: 9916:(40th ed.). London: Churchill Livingstone. 9610:"World's oldest heart found in prehistoric fish" 9461:Colville, Thomas P.; Bassert, Joanna M. (2015). 9422:"Scaling of Cardiovascular Physiology in Snakes" 7953:"Galen and the beginnings of Western physiology" 6054: 4635:, whereas the systemic heart pumps to the body. 4120:and Momoona, the heart and seat of emotions are 2958:level) are often ordered to evaluate a person's 2847:Typically, healthy hearts have only two audible 2491:) whilst others arise from the ventricles (e.g. 2475:or damage within the cardiac conduction system ( 1996:begins to leave it. All the ions travel through 1115:There are two types of cells in cardiac muscle: 1009:. The left atrium has an outpouching called the 9759: 9757: 9460: 8139:. Greenhaven Publishing LLC. 2012. p. 18. 7655:Meletis, John; Konstantopoulos, Kostas (2010). 7650: 7648: 7646: 7644: 7279: 7119:NORD (National Organization for Rare Disorders) 6145: 5330: 5328: 5326: 5184: 4903: 4901: 4899: 4510:, while the other forms the pulmonary artery). 4264:is made of braised heart with an orange sauce. 4186:, they can be used, finely chopped, as part of 3293:. In these procedures, wires are passed from a 2452:, and finally the ventricles (referred to as a 2448:before spreading to the rest of the atria, the 1569:for oxygen in the lungs through the process of 1432:a very different pattern from that of an adult. 1302:(draining the back of the left ventricle), the 1119:which have the ability to contract easily, and 9933:Davidson's principles and practice of medicine 9930: 9892: 9875:Guyton and Hall Textbook of Medical Physiology 9658: 9252:. University of Chicago Press. pp. 448–. 8775:Nature, Center for Humans and (16 June 2017). 8200: 7600: 7444: 7425: 7413: 7401: 7358: 7315: 7288:Davidson's Principles and Practice of Medicine 7273: 6964: 6902: 6734: 6580: 6568: 6534: 6532: 6415: 5965: 5926: 4926: 4866:Taber, Clarence Wilbur; Venes, Donald (2009). 2688:Heart disease is diagnosed by the taking of a 2507:). The most dangerous form of heart racing is 2061:, sensing the stretching of blood vessels and 10579: 10034: 9491: 9454: 9381: 9379: 8990: 8703:. University of Oklahoma Press. pp. 239–240. 8592: 7331:Talley, Nicholas J.; O'Connor, Simon (2013). 6343: 6115: 5480: 4330: 4298:. which in some fish may be connected to the 2766:from within the artery. Any elevation of the 2758:is taken, using either a manual or automatic 2487:), some from the atrioventricular node (e.g. 2471:or bradyarrhythmia. This may be caused by an 1036:is above the left cusp of the valve, and the 787:, visible on the surface of the heart as the 9830: 9754: 9692: 9326: 8876:: CS1 maint: multiple names: authors list ( 8601:, in Piotr Balcerowicz; Marek Mejor (eds.), 8553:: CS1 maint: multiple names: authors list ( 8059:Baylor University Medical Center Proceedings 7946: 7944: 7755: 7753: 7751: 7749: 7747: 7745: 7743: 7641: 6111: 6109: 5912:: CS1 maint: multiple names: authors list ( 5365: 5363: 5361: 5323: 5231: 5178: 4896: 4750:Animated heart 3D model rendered in computer 4541:The tube-like heart (green) of the mosquito 3993:, considered the heart the seat of thought, 3963:, and belongs to fire in the five elements. 2499:), others by an irritable focus (e.g. focal 1202:that are also expressed in skeletal muscle. 1127:which allow a rapid response to impulses of 714:) and is felt to be on the left because the 9836: 9415: 9413: 8469: 8308: 8306: 8304: 7961:AJP: Lung Cellular and Molecular Physiology 7802: 7613: 7611: 7609: 7558:European Journal of Cardio-Thoracic Surgery 6692:European Journal of Cardio-Thoracic Surgery 6529: 6471: 6469: 6467: 6239:Journal of Cardiovascular Electrophysiology 5237: 5141: 5139: 5137: 5135: 5133: 5131: 5129: 5127: 5125: 5123: 5121: 5119: 5117: 5115: 5113: 5111: 5109: 5107: 5105: 5103: 5101: 5099: 5097: 5095: 5093: 5091: 5089: 5087: 5085: 5083: 5081: 5079: 5077: 5075: 5073: 5071: 5069: 5067: 5065: 5063: 5061: 5059: 5057: 5055: 5053: 5051: 5049: 5047: 5045: 5043: 5041: 5039: 5037: 5035: 5033: 5031: 5029: 4936:Biology: Today and Tomorrow With Physiology 3836:; the diamond of purity and essence of the 3685:Blood § Cultural and religious beliefs 3566:Das Reizleitungssystem des SĂ€ugetierherzens 3196: 3119: 2791:The closure of the heart valves causes the 2550: 10586: 10572: 10041: 10027: 9895:Harrison's Principles of Internal Medicine 9736:. Rastogi Publications. pp. 154–155. 9376: 9239: 9047:My Mexico: A Culinary Odyssey with Recipes 8827:Kurian G (2001). "Sacred Heart of Jesus". 8570:A practical dictionary of Chinese medicine 7808: 6421: 5372:Harrison's Principles of Internal Medicine 5027: 5025: 5023: 5021: 5019: 5017: 5015: 5013: 5011: 5009: 4738:Heart illustration with circulatory system 3898:for "happy" (literally, "long of heart"), 3077:, whether there is any backflow of blood ( 1666:The cardiac cycle as correlated to the ECG 1342:The heart receives nerve signals from the 58: 9897:(18 ed.). McGraw-Hill Professional. 9667: 9627: 9569: 9467:. Elsevier Health Sciences. p. 547. 9437: 8567: 8312: 8177: 8086: 8029: 8009: 7941: 7879: 7845: 7828: 7777: 7740: 7723: 7699: 7682: 7672: 7569: 7505: 7335:. Churchill Livingstone. pp. 76–82. 7326: 7324: 7225: 7207: 6933: 6871: 6822: 6767: 6703: 6422:Guyton, Arthur C.; Hall, John E. (2005). 6361: 6213: 6141: 6139: 6106: 6064:, pp. 263–274; Philadelphia: WB Saunders 6029: 5844: 5826: 5485:(32nd ed.). Elsevier. p. 1461. 5416: 5358: 5265: 5255: 5198: 3557:electrical conduction system of the heart 3464:Commentary on Anatomy in Avicenna's Canon 2348: 2221: 1835:The normal rhythmical heart beat, called 1819:Electrical conduction system of the heart 10048: 9843:. John Wiley & Sons. pp. 537–. 9410: 8800: 8447:Death and the afterlife in ancient Egypt 8301: 8262: 7606: 7250:"Brugada syndrome: MedlinePlus Genetics" 6464: 6236: 5620:. Oxford University Press. p. 264. 5483:Dorland's Illustrated Medical Dictionary 4962: 4960: 4846:This article incorporates text from the 4604: 4562: 4536: 4462: 4344: 4222:heart may be grilled or braised. In the 3858:An important part of the concept of the 3815:making a heart sign at a concert in 2018 3807: 3612:. This marked an important milestone in 3513: 3406: 3231: 2975: 2781: 2696:, and further investigations, including 2110: 1943: 1878: 1822: 1812: 1708: 1661: 1533: 1518: 1510: 1426: 1333: 1229: 1091: 1053: 856: 751:, the receiving chambers, and two lower 738: 644:The human heart is in the middle of the 639: 621: 593: 585: 574: 340:, which also contains a small amount of 10595:Physiology of the cardiovascular system 9723: 9492:Crigg, Gordon; Johansen, Kjell (1987). 9419: 9351: 9186:. Sterling Publishing Company. p. 171. 7064: 5006: 4013:, and the seat of reason in the brain. 3989:philosophers and scientists, including 3890:expressions which incorporate the word 1973:is created by the movement of specific 1225: 747:The heart has four chambers, two upper 14: 11170: 10301:moderator band/septomarginal trabecula 9392:. John Wiley & Sons. p. 418. 9322: 9320: 9318: 9316: 9314: 9312: 9249:Hyman's Comparative Vertebrate Anatomy 9202: 9025:, American University in Cairo Press. 8851: 8826: 8774: 8719: 8717: 8629: 8514: 8470:Xigui, Qiu; Mattos, Gilbert L (2000). 8444: 8337: 8159: 8053:Cooper, David K. C. (1 January 2012). 8052: 7321: 7039: 6976: 6344:Davis, J. P.; Tikunova, S. B. (2008). 6170: 6136: 6132:from the original on 28 November 2016. 5615: 5505: 5346:from the original on 19 September 2014 4870:. F. A. Davis Co. pp. 1018–1023. 3670: 3377:mineralocorticoid receptor antagonists 3226:Transcatheter aortic valve replacement 2514: 2433: 10567: 10022: 9857:from the original on 6 December 2016. 9784:from the original on 6 December 2016. 9750:from the original on 6 December 2016. 9719:from the original on 6 December 2016. 9688:from the original on 6 December 2016. 9654:from the original on 6 December 2016. 9607: 9601: 9481:from the original on 6 December 2016. 9406:from the original on 6 December 2016. 9358:. University of Texas Press. p.  9277:Shuttleworth, Trevor J., ed. (1988). 9266:from the original on 6 December 2016. 9098:. The Bobbs-Merrill Company. p.  9049:, University of Texas Press. p. 100. 8991:Pawley, Andrew; Hammarström, Harald. 8654: 8394: 7766:Journal of Thrombosis and Haemostasis 7547: 7545: 7507:10.1016/j.atherosclerosis.2016.05.037 7463:. Lippincott Williams & Wilkins. 7370: 6799: 6797: 6795: 6745: 6743: 6681: 6679: 6597: 6595: 6593: 6591: 6589: 6337: 5997:from the original on 16 November 2001 5462:from the original on 20 November 2010 5166:from the original on 27 February 2021 5145: 4957: 4868:Taber's cyclopedic medical dictionary 4859: 4675:The human heart viewed from the front 4627:have two "gill hearts" also known as 4594:which carries the most commonly used 4406:, which have a four-chambered heart. 3944:, the heart is seen as the center of 3569:, in 1906. Tawara's discovery of the 3341:, or inherited arrhythmia syndromes. 3193:) to a point beyond the obstruction. 3003:(ventricular depolarisation) and the 2657:Progressive cardiac conduction defect 1831:through the heart's conduction system 1549:The heart functions as a pump in the 648:, with its apex pointing to the left. 617: 9812:Smithsonian National Zoological Park 9633: 9137: 8619:from the original on 6 December 2016 8217:10.1146/annurev.med.53.082901.104050 7950: 7851: 7759: 7705: 7196:Frontiers in Cardiovascular Medicine 6507:"Your Heart Failure Healthcare Team" 6196:Antz, Matthias; et al. (1998). 6195: 5738:from the original on 9 November 2018 4661: 4617:In some other invertebrates such as 4305:The sinoatrial node is found in all 4178:. They can also be pan-fried, as in 4124:, meaning they share the same word. 4016:The heart also played a role in the 3313:) can also be treated using open or 2965: 2888:or congenital heart disease such as 2827:Normal heart sounds as heard with a 2738:) and listening with a stethoscope ( 2712:. Other invasive procedures such as 1451:in the neural plate which forms the 667:. A double-membraned sac called the 9608:Ghosh, Pallab (15 September 2022). 9558:The Journal of Experimental Biology 9530:from the original on 28 August 2021 9501:Journal of Comparative Physiology B 9426:Integrative and Comparative Biology 9389:Veterinary Anesthesia and Analgesia 9309: 9146:and Rombauer Becker, Marion (1975) 8714: 8378:. The word was also transcribed by 7725:10.1161/CIRCHEARTFAILURE.108.772756 7629:from the original on 18 August 2016 7530:from the original on 28 August 2021 7477:from the original on 23 April 2016. 6977:MarbĂĄn, Eduardo (10 January 2002). 6118:"Use of inotropes in critical care" 5708:from the original on 23 August 2018 4785:Supplying blood to the heart itself 4726:An anatomical specimen of the heart 4571:body structure – heart shown in red 4235:in a spice and vinegar mixture. An 4059:and the parallel veneration of the 3651:By the middle of the 20th century, 2962:and diabetes status, respectively. 2594:transposition of the great arteries 2314: 2249:. In the worst case this may cause 652:The human heart is situated in the 324:and their left counterparts as the 24: 9796:https://doi.org/10.1007/BF02908733 9729: 9297:from the original on 14 April 2021 8535:from the original on 14 April 2021 8472:Chinese writing = Wenzi-xue-gaiyao 7809:Michelakis, E. D. (19 June 2014). 7623:University of Sydney Online Museum 7542: 7383:from the original on 6 August 2016 6873:10.1161/01.CIR.0000091380.04100.84 6792: 6740: 6676: 6586: 6550:from the original on 12 March 2016 6517:from the original on 10 March 2016 6487:from the original on 10 March 2016 6411:from the original on 23 June 2017. 6394:National Health Statistics Reports 6313:from the original on 14 April 2012 6287:from the original on 1 August 2012 6283:. MedicineNet.com. 27 April 2011. 5879: 5682:from the original on 17 March 2016 5436:from the original on 27 April 2019 4714:Frontal section of the human heart 4687:The human heart viewed from behind 3778:is often used as a "heart" symbol. 3344: 3168:percutaneous coronary intervention 2801: 2603: 2361: 1900: 1338:Autonomic innervation of the heart 522: 25: 11199: 9950: 9770:. Cengage Learning. p. 939. 9589:from the original on 3 March 2015 9280:Physiology of Elasmobranch Fishes 8630:Lanman, Charles Rockwell (1996). 8568:Wiseman, Nigel; Ye, Feng (1998). 8315:The Watkins Dictionary of Symbols 8313:Tresidder, Jack (2012). "Heart". 8031:10.1161/CIRCULATIONAHA.106.616771 8010:Silverman, M. E. (13 June 2006). 6664:from the original on 14 June 2020 6611:European Journal of Heart Failure 4939:. Cengage Learning. p. 422. 4502:, into the rest of the body. (In 4256:made with pig heart and blood. A 4078:for a lost one or to unfulfilled 4074:is a cross-cultural reference to 3596:in a human ever performed was by 3457:The earliest descriptions of the 3384:cardiac resynchronisation therapy 2590:cyanotic congenital heart defects 1698: 1346:and from nerves arising from the 793:posterior interventricular sulcus 9983:Prenatal human heart development 9800: 9788: 9699:Farrell, Anthony P, ed. (2011). 9640:. Garland Science. p. 134. 9345: 9270: 9217:10.1046/j.1440-1681.2003.03876.x 9196: 9176: 9155: 9126:, University of Virginia Press, 9116: 9080: 9060: 9036: 9015: 8999: 8984: 8959: 8934: 8909: 8884: 8845: 8820: 8794: 8768: 8743: 8693: 8677: 8648: 8623: 8586: 8561: 8508: 8488: 8463: 8438: 8413: 8388: 8356: 8331: 8256: 8231: 8194: 8179:10.1111/j.1525-1594.2011.01235.x 8153: 8129: 8103: 8046: 8003: 7896: 7779:10.1111/j.1538-7836.2011.04312.x 7373:"Acute Coronary Syndrome Workup" 6477:"Cardiovascular diseases (CVDs)" 6251:10.1046/j.1540-8167.2002.00001.x 6080:DuBose, Terry J. (26 July 2011) 4987:from the original on 4 May 2016. 4953:from the original on 2 May 2016. 4743: 4731: 4719: 4707: 4692: 4680: 4668: 4642:(including vertebrates) and the 4532: 4424: 4267: 3866:was thought to be the heart, or 3820:or throne of God in Islamic and 3783: 3763: 3748: 3563:published his monograph, titled 3528:(1628) by the English physician 3411:Heart and its blood vessels, by 3104:, and indicate whether there is 2838:Problems playing this file? See 2817: 2628:sudden arrhythmic death syndrome 2397:Problems playing this file? See 2377: 2272: 2150: 2124: 1935:Problems playing this file? See 1916: 1643: 1577: 1317:Small lymphatic networks called 970:, which are also present in the 843: 831: 561:Problems playing this file? See 538: 41:. For the comics character, see 9865: 9184:The Connoisseur's Guide to Meat 8664:. book 3, ch. 4. Archived from 8266:New England Journal of Medicine 7872:10.1152/japplphysiol.91171.2008 7481: 7450: 7364: 7242: 7182: 7157: 7132: 7107: 7040:Marban, Eduardo (1 July 2003). 7033: 6970: 6908: 6847: 6499: 6378: 6299: 6273: 6230: 6189: 6164: 6074: 6009: 5983: 5873: 5802: 5750: 5720: 5694: 5663: 5609: 5530: 5499: 5474: 5448: 5388: 4828: 4815: 4652:common ancestor of these groups 4551:(also green) and surrounded by 3966:The Sanskrit word for heart is 3824:thought; the divine centre, or 3324:Cardiac devices in the form of 2980:Cardiac cycle shown against ECG 2777: 2567:hypoplastic left heart syndrome 2489:AV nodal re-entrant tachycardia 2460:increase the long term risk of 1961:, created and sustained by the 1625: 1329: 1194:. Other proteins expressed are 27:Organ found inside most animals 9973:Atlas of Human Cardiac Anatomy 9674:. Elsevier. pp. 154–155. 9163:Beef: And Other Bovine Matters 8688:De usu partium corporis humani 8071:10.1080/08998280.2012.11928783 6424:Textbook of medical physiology 5991:"Main Frame Heart Development" 5676:Atlas of Human Cardiac Anatomy 4806: 4797: 4788: 4779: 4770: 4761: 4278: 4089:'s arrows" is ancient, due to 3130:Coronary artery bypass surgery 2899: 2719: 2505:Wolff-Parkinson-White syndrome 2422:). In some parts of the world 1883:Conduction system of the heart 1410: 1403:. Norepinephrine binds to the 1364:parasympathetic nervous system 1324:inferior tracheobronchial node 1205: 927: 912:is located at the base of the 439:close to 72 beats per minute. 385:conduction system of the heart 13: 1: 10722:Aortic valve area calculation 9668:Ostrander, Gary Kent (2000). 9355:The Ruby-Throated Hummingbird 7859:Journal of Applied Physiology 7830:10.1161/CIRCRESAHA.115.301132 7460:Feigenbaum's Echocardiography 5552:10.1016/j.carpath.2018.04.009 5342:. World Health Organization. 5291:, pp. 101, 157–158, 180. 4840: 3452: 3212:. In some circumstances, the 2999:(atrial depolarisation), the 2742:). It involves assessment of 2663:Early repolarisation syndrome 2339:arrhythmogenic cardiomyopathy 2160:is a condition affecting the 2043: 1887: 1561:to and from the body and the 1515:Blood flow through the valves 1506: 1493: 1108:surrounded by a framework of 993: 367:The heart pumps blood with a 9637:Instant Notes Animal Biology 9634:Jurd, Richard David (2004). 9246:Hyman, L. Henrietta (1992). 8781:Center for Humans and Nature 7603:, pp. 585–588, 614–623. 5880:J., Tortora, Gerard (2009). 5238:de Lussanet, M.H.E. (2019). 4625:Squids and other cephalopods 4341:Snake § Internal organs 4149:hearts are considered to be 4032:): "round, hot, pulsating". 4001:in particular is due to the 3739: 3246:Artificial cardiac pacemaker 3175:coronary artery bypass graft 3111: 2683: 2373:Mitral Valve Prolapse murmur 2131:The stethoscope is used for 1530:Blood flow through the heart 1147:. Cardiac muscle tissue has 789:anterior longitudinal sulcus 707:with the costal cartilages. 570: 281:to the body, while carrying 7: 10839:Effective refractory period 10718:) / End-diastolic dimension 10504:sternopericardial ligaments 10281:valve of inferior vena cava 8993:The Trans New Guinea family 8755:WISDOM WEAVERS OF THE WORLD 8515:Rogers, Flaws, Bob (2007). 8243:www.medschool.umaryland.edu 7951:West, J. B. (30 May 2014). 6309:. About.com. 9 April 2012. 5882:Principles of human anatomy 5506:Bianco, Carl (April 2000). 4910:Clinically Oriented Anatomy 4654:(may have been lost in the 4202:ragu iz kurinyikh potrokhov 3961:six organs and five viscera 2764:a more invasive measurement 2327:hypertrophic cardiomyopathy 2208:allied health practitioners 2115: 1741:, duration of contraction, 1449:splanchnopleuric mesenchyme 734: 273:. The pumped blood carries 10: 11204: 10102:posterior interventricular 9988:Animal hearts: fish, squid 9420:Seymour, Roger S. (1987). 9122:Schwabe, Calvin W. (1979) 8801:Bioneers (22 March 2019). 8160:Cooley, Denton A. (2011). 7974:10.1152/ajplung.00123.2014 7712:Circulation: Heart Failure 7706:Katz, A. M. (1 May 2008). 7371:Coven, David; Yang, Eric. 6540:"Different heart diseases" 6148:Oh's Intensive Care Manual 6040:10.1177/875647939000600306 4794:From the body to the heart 4767:From the heart to the body 4456: 4337:Reptile § Circulation 4334: 4331:Double circulatory systems 4323:and up to 1200 bpm in the 4271: 4114:Trans-New Guinea languages 4105:theme that became tied to 3844:centre of understanding." 3832:of transcendent wisdom in 3692: 3674: 3489:De humani corporis fabrica 3402: 3397: 3348: 3330:implantable defibrillators 3235: 3200: 3123: 3026: 3022: 2969: 2925:MB form of creatine kinase 2890:ventricular septal defects 2723: 2607: 2575:congenital aortic stenosis 2554: 2473:abnormally slow sinus node 2437: 2352: 2335:restrictive cardiomyopathy 2318: 2276: 2225: 2018:absolute refractory period 1891: 1816: 1702: 1647: 1499: 1416: 1237: 1209: 1079:simple squamous epithelium 1047: 820: 613:Anatomy of the human heart 610: 36: 29: 11124:Tubuloglomerular feedback 11079: 11071:Critical closing pressure 11029: 10996: 10982: 10962: 10899: 10891:Hexaxial reference system 10814:Cardiac electrophysiology 10801: 10745: 10697: 10610: 10601: 10535: 10516:epicardium/visceral layer 10489: 10471: 10416: 10398: 10391: 10329: 10305:crista supraventricularis 10239: 10232: 10206: 10134: 10127: 10097:anterior interventricular 10064: 10057: 8317:. Watkins Media Limited. 8204:Annual Review of Medicine 7760:Aird, W. C. (July 2011). 7085:10.1016/j.hlc.2018.09.007 7042:"Cardiac Channelopathies" 6979:"Cardiac channelopathies" 6481:World Health Organization 6215:10.1161/01.CIR.98.17.1790 5828:10.1186/s12864-015-1686-y 5670:University of Minnesota. 5146:Betts, J. Gordon (2013). 4459:Fish anatomy § Heart 4385:double circulatory system 4325:ruby-throated hummingbird 3864:Ancient Egyptian religion 3509: 3388:ventricular assist device 3284:novel oral anticoagulants 2917:brain natriuretic peptide 2571:ventricular septal defect 2172:may result or at worse a 1362:. The vagus nerve of the 1273:left main coronary artery 1040:is above the right cusp. 816: 371:determined by a group of 362:developmental axial twist 316:and lower left and right 231: 219: 207: 195: 183: 171: 166: 150: 114: 109:left main coronary artery 86: 74: 69: 57: 52: 11099:Renin–angiotensin system 9837:Ladd, Prosser C (1991). 8494:MDBG online dictionary. 8445:Taylor, John H. (2001). 8395:Allen, James P. (2014). 6935:10.1093/eurheartj/ehq249 6171:Pocock, Gillian (2006). 6146:Bersten, Andrew (2013). 5616:Pocock, Gillian (2006). 5540:Cardiovascular Pathology 5418:10.1093/eurheartj/ehm316 5209:10.1163/157075611X617102 5149:Anatomy & physiology 4755: 4390:In reptiles, other than 4061:Immaculate Heart of Mary 3542:Frank–Starling mechanism 3503:Christianismi Restitutio 3256:calcium channel blockers 3250:Abnormal heart rhythms ( 3065:), or by a probe in the 2894:pericardial friction rub 2851:, called S1 and S2. The 2619:electrochemical gradient 2579:coarctation of the aorta 2551:Congenital heart disease 2509:ventricular fibrillation 1971:cardiac action potential 1829:cardiac action potential 1807:calcium channel blockers 1758:Frank-Starling mechanism 1553:to provide a continuous 1281:left anterior descending 1104:—a layer of involuntary 869:on the right and to the 861:Frontal section showing 473:, and poorly controlled 457:. Risk factors include: 11129:Cerebral autoregulation 11094:Kinin–kallikrein system 11061:Jugular venous pressure 10711:End-diastolic dimension 10689:Pressure volume diagram 10285:valve of coronary sinus 10198:atrioventricular septum 10166:interventricular septum 10011:EncyclopĂŠdia Britannica 8699:Sandstrom, Alan (1991) 8661:On the Parts of Animals 7209:10.3389/fcvm.2018.00169 6824:10.1093/europace/eut206 6769:10.1093/europace/euw295 6350:Cardiovascular Research 6281:"Definition of SA node" 6082:Sex, Heart Rate and Age 5772:10.1126/science.1260419 5704:. The Free Dictionary. 4452: 4262:cƓur de porc Ă  l'orange 4127: 3886:. This is evidenced by 3559:remained unknown until 3467:, published in 1242 by 3260:sodium channel blockers 3242:Radiofrequency ablation 3220:valves can be repaired 3187:internal mammary artery 3126:Coronary artery disease 3013:Testing when exercising 2714:cardiac catheterisation 2557:Congenital heart defect 2497:ventricular tachycardia 2493:ventricular tachycardia 2424:rheumatic heart disease 2305:jugular venous pressure 2228:Coronary artery disease 2200:cardiothoracic surgeons 2184:Cardiovascular diseases 1858:atrioventricular septum 1447:The heart derives from 1401:positively charged ions 1043: 785:interventricular septum 761:atrioventricular septum 757:atrioventricular valves 451:coronary artery disease 447:Cardiovascular diseases 435:. The heart beats at a 11066:Portal venous pressure 11056:Mean arterial pressure 10970:Ventricular remodeling 10716:End-systolic dimension 10674:Cardiac function curve 10523:fold of left vena cava 10273:limbus of fossa ovalis 9352:Osborne, June (1998). 9182:Milsom, Jennie (2009) 9066:Sacharow, Alla (1993) 8593:Sellmer, Sven (2004), 8501:4 October 2016 at the 8425:www.ancientegypt.co.uk 8374:7 January 2009 at the 7619:"Anatomy of the Heart" 6922:European Heart Journal 6544:World Heart Federation 6459:Guyton & Hall 2011 6447:Guyton & Hall 2011 6332:Guyton & Hall 2011 6101:Guyton & Hall 2011 6018:J Diagn Med Sonography 5508:"How Your Heart Works" 5405:European Heart Journal 5318:Guyton & Hall 2011 5306:Guyton & Hall 2011 5289:Guyton & Hall 2011 4891:Guyton & Hall 2011 4614: 4572: 4560: 4470: 4372: 3851:, the word for heart, 3816: 3657:Framingham Heart Study 3606:Groote Schuur Hospital 3519: 3416: 3357:ischemic heart disease 3203:Artificial heart valve 3197:Valvular heart disease 3120:Ischemic heart disease 3106:fluid around the heart 2981: 2806: 2796: 2716:can also play a role. 2366: 2355:Valvular heart disease 2349:Valvular heart disease 2331:dilated cardiomyopathy 2297:valvular heart disease 2293:ischemic heart disease 2222:Ischemic heart disease 2091:, norepinephrine, and 2054:cardiovascular centres 1950: 1905: 1884: 1832: 1714: 1667: 1546: 1531: 1516: 1433: 1396:neuromuscular junction 1356:cardiovascular centres 1339: 1312:anterior cardiac veins 1300:posterior cardiac vein 1285:left circumflex artery 1252:and a way of removing 1235: 1106:striated muscle tissue 1097: 1059: 972:right atrial appendage 920:is at the base of the 878: 769:right atrial appendage 744: 649: 637: 608: 591: 583: 579:Human heart during an 534:A teenager's heartbeat 527: 233:Anatomical terminology 145:anterior cardiac veins 32:Heart (disambiguation) 10707:Fractional shortening 10319:pulmonary circulation 9571:10.1242/jeb.199.2.359 9124:Unmentionable Cuisine 8831:. Thomas Nelson Inc. 8672:De partibus animalium 8338:Rosner, Fred (1995). 5320:, pp. 1039–1041. 4608: 4566: 4540: 4466: 4348: 4335:Further information: 4228:anticuchos de corazĂłn 4180:Jerusalem mixed grill 4136:, for example in the 4057:Sacred Heart of Jesus 3913:Weighing of the Heart 3811: 3675:Further information: 3571:atrioventricular node 3517: 3410: 3141:myocardial infarction 2979: 2952:fasting blood glucose 2940:basic metabolic panel 2805: 2785: 2770:is noted. A person's 2748:splinter haemorrhages 2624:sudden death syndrome 2450:atrioventricular node 2365: 2188:high-income countries 2111:Clinical significance 1947: 1904: 1882: 1854:atrioventricular node 1826: 1813:Electrical conduction 1712: 1665: 1563:pulmonary circulation 1544: 1529: 1514: 1430: 1337: 1277:right coronary artery 1233: 1095: 1057: 1048:Further information: 1038:right coronary artery 1011:left atrial appendage 860: 773:left atrial appendage 742: 643: 632: 606: 589: 578: 526: 397:pulmonary circulation 381:atrioventricular node 364:in the early embryo. 105:right coronary artery 10647:End-diastolic volume 10548:Coronary circulation 10377:systemic circulation 10216:intervenous tubercle 9733:Fish & Fisheries 9161:Torode, John (2009) 8279:10.1056/NEJMra063052 7816:Circulation Research 7571:10.1093/ejcts/ezu366 7333:Clinical Examination 6705:10.1093/ejcts/ezs455 5732:www.proteinatlas.org 4821:Note the muscles do 4701:coronary circulation 4555:(red). Blue depicts 4195:pollo en menudencias 4168:churrasco de coração 4070:The expression of a 3638:genetically modified 3442:The Greek physician 2886:damaged heart valves 2768:jugular venous pulse 2598:atrial septal defect 2563:patent foramen ovale 2537:pericardial effusion 2085:basal metabolic rate 1787:intensive care units 1559:systemic circulation 1442:prenatal development 1240:Coronary circulation 1226:Coronary circulation 1034:left coronary artery 411:, traveling through 409:systemic circulation 393:inferior venae cavae 11011:Vascular resistance 10849:Electrocardiography 10844:Pacemaker potential 10774:Conduction velocity 10679:Venous return curve 10652:End-systolic volume 10499:fibrous pericardium 9872:Hall, John (2011). 9671:The Laboratory Fish 9439:10.1093/icb/27.1.97 9329:The Vertebrate Body 7852:West, John (2008). 7674:10.1155/2010/857657 7447:, pp. 528–530. 7428:, pp. 521–640. 7361:, pp. 556–559. 7318:, pp. 522–536. 7276:, pp. 527–534. 6995:2002Natur.415..213M 6905:, pp. 638–639. 6334:, pp. 115–120. 6122:Clinical Pharmacist 6103:, pp. 110–113. 5993:. Meddean.luc.edu. 5978:Gray's Anatomy 2008 5954:Gray's Anatomy 2008 5939:Gray's Anatomy 2008 5868:Gray's Anatomy 2008 5672:"Papillary Muscles" 5658:Gray's Anatomy 2008 5648:, pp. 966–967. 5646:Gray's Anatomy 2008 5606:, pp. 964–967. 5604:Gray's Anatomy 2008 5594:, pp. 960–962. 5592:Gray's Anatomy 2008 5308:, pp. 105–107. 5001:Gray's Anatomy 2008 4596:respiratory pigment 4176:chicken heart satay 3942:In Chinese medicine 3934:. The Chinese word 3794:glyph for "heart" ( 3671:Society and culture 3646:Bartley P. Griffith 3394:may be considered. 3311:atrial fibrillation 3232:Cardiac arrhythmias 3087:cardiac stress test 3009:rhythm disturbances 2990:electrically ground 2972:Electrocardiography 2813:Normal heart sounds 2726:Cardiac examination 2694:cardiac examination 2639:Torsades de pointes 2583:Tetralogy of Fallot 2515:Pericardial disease 2458:atrial fibrillation 2454:normal sinus rhythm 2434:Cardiac arrhythmias 2265:, smoking and high 2259:high blood pressure 1768:vascular resistance 1693:inferior vena cavae 1609:. As these pass by 1423:Human embryogenesis 1308:small cardiac veins 1304:middle cardiac vein 1154:There are specific 712:offset to the right 483:shortness of breath 471:high blood pressure 465:, little exercise, 261:. This organ pumps 137:middle cardiac vein 99:and right and left 43:Cardiac (character) 11119:Myogenic mechanism 10737:Left atrial volume 10669:Frank–Starling law 10543:Circulatory system 10511:serous pericardium 10473:Pericardial cavity 10171:trabeculae carneae 10144:interatrial septum 9967:What Is the Heart? 9808:"Meet our animals" 9513:10.1007/BF00693365 9149:The Joy of Cooking 9094:The Joy of Cooking 9006:Indonesia Magazine 8668:on 14 August 2016. 8595:"The Heart in the 7919:10.1111/apha.12309 7115:"Long QT Syndrome" 6967:, p. 1458–65. 6737:, pp. 612–13. 6363:10.1093/cvr/cvm098 6087:2 May 2014 at the 6060:DuBose, TJ (1996) 5702:"pectinate muscle" 5481:Dorland's (2012). 5257:10.7717/peerj.7096 4615: 4573: 4561: 4515:cartilaginous fish 4471: 4447:foramen of Panizza 4373: 4274:Circulatory system 4216:stir-fried heart. 4063:, made popular by 3817: 3602:Christiaan Barnard 3520: 3417: 3392:cardiac transplant 3335:slow heart rhythms 2982: 2944:coagulation screen 2934:investigating for 2873:fourth heart sound 2857:second heart sound 2807: 2797: 2706:electrocardiograms 2545:pericardiocentesis 2501:atrial tachycardia 2430:throat infection. 2367: 2162:circulatory system 2006:potassium channels 1955:resting heart rate 1951: 1912:A racing heartbeat 1906: 1885: 1868:to left and right 1833: 1827:Transmission of a 1785:, particularly in 1722:and is called the 1715: 1668: 1613:carbon dioxide is 1551:circulatory system 1547: 1532: 1517: 1502:Cardiac physiology 1453:cardiogenic region 1434: 1352:Sympathetic nerves 1340: 1296:great cardiac vein 1236: 1156:proteins expressed 1125:intercalated discs 1098: 1060: 1024:, but there is no 1022:trabeculae carneae 979:trabeculae carneae 879: 745: 658:thoracic vertebrae 656:, at the level of 650: 638: 636:of the human heart 618:Location and shape 609: 592: 584: 528: 501:, as well as with 271:circulatory system 141:small cardiac vein 133:great cardiac vein 125:inferior vena cava 121:Superior vena cava 101:pulmonary arteries 11165: 11164: 11161: 11160: 10978: 10977: 10818:Action potential 10809:Conduction system 10755:Cardiac pacemaker 10727:Ejection fraction 10561: 10560: 10553:Coronary arteries 10531: 10530: 10481:pericardial sinus 10441:Bachmann's bundle 10431:cardiac pacemaker 10426:Conduction system 10387: 10386: 10277:crista terminalis 10228: 10227: 10224: 10223: 10176:chordae tendineae 10149:pectinate muscles 9942:978-0-7020-3085-7 9923:978-0-8089-2371-8 9904:978-0-07-174889-6 9885:978-1-4160-4574-8 9850:978-0-471-85767-9 9777:978-1-133-17032-7 9743:978-81-7133-800-9 9712:978-0-08-092323-9 9681:978-0-12-529650-2 9647:978-1-85996-325-8 9474:978-0-323-35620-6 9399:978-1-118-52620-0 9369:978-0-292-76047-9 9338:978-0-03-910284-5 9290:978-3-642-73336-9 9259:978-0-226-87013-7 9165:, Taunton Press, 9144:Rombauer, Irma S. 9109:978-0-02-604570-4 9088:Rombauer, Irma S. 8863:978-0-19-968027-6 8838:978-1-4185-3981-8 8701:Corn is Our Blood 8641:978-81-208-1363-2 8612:978-81-208-1978-8 8579:978-0-912111-54-4 8528:978-0-936185-52-1 8481:978-1-55729-071-7 8456:978-0-226-79164-7 8406:978-1-107-66328-2 8349:978-0-88125-506-5 8324:978-1-78028-357-9 8273:(11): 1140–1151. 8166:Artificial Organs 8117:. 3 December 2017 8024:(23): 2775–2781. 7906:Acta Physiologica 7470:978-0-7817-9557-9 7342:978-0-7295-4198-5 7297:978-0-7020-3084-0 6989:(6868): 213–218. 6928:(23): 2915–2957. 6866:(15): 1871–1909. 6762:(11): 1609–1678. 6433:978-0-7216-0240-0 6307:"Purkinje Fibers" 6208:(17): 1790–1795. 6182:978-0-19-856878-0 6157:978-0-7020-4762-6 5891:978-0-471-78931-4 5766:(6220): 1260419. 5627:978-0-19-856878-0 5492:978-1-4160-6257-8 5411:(19): 2375–2414. 5381:978-0-07-174889-6 5159:978-1-938168-13-0 4980:978-1-4195-5281-6 4946:978-0-495-56157-6 4919:978-1-60547-652-0 4877:978-0-8036-1559-5 4662:Additional images 4553:pericardial cells 4544:Anopheles gambiae 4319:to around 600 in 4290:, with hearts in 3907:and a variety of 3737: 3736: 3708: 3707: 3704: 3703: 3644:by heart surgeon 3634:Adrian Kantrowitz 3630:Vladimir Demikhov 3413:Leonardo da Vinci 3291:catheter ablation 3083:ejection fraction 2966:Electrocardiogram 2869:third heart sound 2853:first heart sound 2822: 2787:3D echocardiogram 2645:Short QT syndrome 2541:cardiac tamponade 2383: 2289:peripheral oedema 2166:coronary arteries 2107:may increase it. 2078:Bainbridge reflex 1922: 1850:Bachmann's bundle 1720:body surface area 1542: 1527: 1457:endocardial tubes 1419:Heart development 1368:sympathetic trunk 1360:medulla oblongata 1348:sympathetic trunk 1266:lymphatic vessels 1219:pericardial fluid 1015:pectinate muscles 968:pectinate muscles 894:papillary muscles 875:chordae tendineae 863:papillary muscles 759:, present in the 630: 604: 544: 247: 246: 242: 127:, right and left 16:(Redirected from 11195: 11188:Organs (anatomy) 11104:Vasoconstrictors 11081:Regulation of BP 10994: 10993: 10927:pulmonary artery 10900:Chamber pressure 10608: 10607: 10588: 10581: 10574: 10565: 10564: 10396: 10395: 10351:atrial appendage 10315:pulmonary artery 10265:atrial appendage 10237: 10236: 10211:cardiac skeleton 10181:papillary muscle 10132: 10131: 10062: 10061: 10043: 10036: 10029: 10020: 10019: 10015: 10007: 9946: 9927: 9908: 9889: 9859: 9858: 9834: 9828: 9827: 9825: 9823: 9814:. Archived from 9804: 9798: 9792: 9786: 9785: 9761: 9752: 9751: 9727: 9721: 9720: 9696: 9690: 9689: 9665: 9656: 9655: 9631: 9625: 9624: 9622: 9620: 9605: 9599: 9598: 9596: 9594: 9588: 9573: 9555: 9546: 9540: 9539: 9537: 9535: 9529: 9498: 9489: 9483: 9482: 9458: 9452: 9451: 9441: 9417: 9408: 9407: 9383: 9374: 9373: 9349: 9343: 9342: 9324: 9307: 9306: 9304: 9302: 9274: 9268: 9267: 9243: 9237: 9236: 9200: 9194: 9180: 9174: 9159: 9153: 9141: 9135: 9120: 9114: 9113: 9097: 9084: 9078: 9064: 9058: 9040: 9034: 9019: 9013: 9003: 8997: 8996: 8988: 8982: 8981: 8979: 8977: 8963: 8957: 8956: 8954: 8952: 8938: 8932: 8931: 8929: 8927: 8913: 8907: 8906: 8904: 8902: 8888: 8882: 8881: 8875: 8867: 8849: 8843: 8842: 8824: 8818: 8817: 8815: 8813: 8798: 8792: 8791: 8789: 8787: 8772: 8766: 8765: 8763: 8761: 8747: 8741: 8740: 8738: 8736: 8721: 8712: 8697: 8691: 8681: 8675: 8669: 8652: 8646: 8645: 8627: 8621: 8620: 8590: 8584: 8583: 8565: 8559: 8558: 8552: 8544: 8542: 8540: 8512: 8506: 8492: 8486: 8485: 8467: 8461: 8460: 8442: 8436: 8435: 8433: 8431: 8417: 8411: 8410: 8392: 8386: 8360: 8354: 8353: 8335: 8329: 8328: 8310: 8299: 8298: 8260: 8254: 8253: 8251: 8249: 8235: 8229: 8228: 8198: 8192: 8191: 8181: 8157: 8151: 8150: 8133: 8127: 8126: 8124: 8122: 8107: 8101: 8100: 8090: 8050: 8044: 8043: 8033: 8007: 8001: 8000: 7999:on 2 March 2019. 7998: 7992:. Archived from 7968:(2): L121–L128. 7957: 7948: 7939: 7938: 7900: 7894: 7893: 7883: 7866:(6): 1877–1880. 7849: 7843: 7842: 7832: 7806: 7800: 7799: 7781: 7757: 7738: 7737: 7727: 7703: 7697: 7696: 7686: 7676: 7652: 7639: 7638: 7636: 7634: 7615: 7604: 7598: 7592: 7591: 7573: 7549: 7540: 7539: 7537: 7535: 7509: 7485: 7479: 7478: 7454: 7448: 7442: 7429: 7423: 7417: 7411: 7405: 7399: 7393: 7392: 7390: 7388: 7368: 7362: 7356: 7347: 7346: 7328: 7319: 7313: 7302: 7301: 7283: 7277: 7271: 7265: 7264: 7262: 7260: 7246: 7240: 7239: 7229: 7211: 7186: 7180: 7179: 7177: 7175: 7161: 7155: 7154: 7152: 7150: 7136: 7130: 7129: 7127: 7125: 7111: 7105: 7104: 7068: 7062: 7061: 7037: 7031: 7030: 6974: 6968: 6962: 6956: 6955: 6937: 6912: 6906: 6900: 6894: 6893: 6875: 6851: 6845: 6844: 6826: 6817:(8): 1070–1118. 6801: 6790: 6789: 6771: 6747: 6738: 6732: 6726: 6725: 6707: 6683: 6674: 6673: 6671: 6669: 6663: 6623:10.1002/ejhf.592 6608: 6599: 6584: 6578: 6572: 6566: 6560: 6559: 6557: 6555: 6536: 6527: 6526: 6524: 6522: 6503: 6497: 6496: 6494: 6492: 6473: 6462: 6456: 6450: 6444: 6438: 6437: 6419: 6413: 6412: 6410: 6391: 6382: 6376: 6375: 6365: 6341: 6335: 6329: 6323: 6322: 6320: 6318: 6303: 6297: 6296: 6294: 6292: 6277: 6271: 6270: 6234: 6228: 6227: 6217: 6193: 6187: 6186: 6173:Human Physiology 6168: 6162: 6161: 6143: 6134: 6133: 6113: 6104: 6098: 6092: 6078: 6072: 6062:Fetal Sonography 6058: 6052: 6051: 6033: 6013: 6007: 6006: 6004: 6002: 5987: 5981: 5975: 5969: 5963: 5957: 5951: 5942: 5936: 5930: 5924: 5918: 5917: 5911: 5903: 5877: 5871: 5865: 5859: 5858: 5848: 5830: 5806: 5800: 5799: 5754: 5748: 5747: 5745: 5743: 5724: 5718: 5717: 5715: 5713: 5698: 5692: 5691: 5689: 5687: 5667: 5661: 5655: 5649: 5643: 5632: 5631: 5618:Human Physiology 5613: 5607: 5601: 5595: 5589: 5580: 5579: 5534: 5528: 5527: 5525: 5523: 5514:. Archived from 5503: 5497: 5496: 5478: 5472: 5471: 5469: 5467: 5458:. Bartleby.com. 5452: 5446: 5445: 5443: 5441: 5435: 5420: 5402: 5392: 5386: 5385: 5367: 5356: 5355: 5353: 5351: 5332: 5321: 5315: 5309: 5303: 5292: 5286: 5280: 5279: 5269: 5259: 5235: 5229: 5228: 5202: 5182: 5176: 5175: 5173: 5171: 5143: 5004: 4998: 4989: 4988: 4964: 4955: 4954: 4930: 4924: 4923: 4905: 4894: 4888: 4882: 4881: 4863: 4835: 4832: 4826: 4819: 4813: 4810: 4804: 4801: 4795: 4792: 4786: 4783: 4777: 4774: 4768: 4765: 4747: 4735: 4723: 4711: 4696: 4684: 4672: 4629:branchial hearts 4492:conus arteriosus 4419:conus arteriosus 4409:In the heart of 4365:Conus arteriosus 4212:the meat, as in 4184:Egyptian cuisine 3787: 3767: 3752: 3697: 3696: 3693: 3689: 3688: 3618:Louis Washkansky 3594:heart transplant 3587:Willem Einthoven 3498:Michael Servetus 3492:(1543), but his 3484:Andreas Vesalius 3339:cardiomyopathies 3238:Heart arrhythmia 3210:prosthetic valve 3102:pulmonary oedema 3043:echocardiography 2932:full blood count 2824: 2823: 2804: 2760:sphygmomanometer 2677:Brugada syndrome 2635:Long QT Syndrome 2385: 2384: 2364: 2315:Cardiomyopathies 2301:cardiomyopathies 2212:physiotherapists 2154: 2128: 2097:low blood oxygen 2093:thyroid hormones 2026:troponin complex 1967:action potential 1924: 1923: 1903: 1862:cardiac skeleton 1543: 1528: 1484:beats per minute 1383:thoracic ganglia 1254:metabolic wastes 1129:action potential 914:pulmonary artery 890:chordae tendinae 873:on the left via 865:attached to the 847: 835: 803:cardiac skeleton 673:vertebral column 631: 607:Cardiology video 605: 546: 545: 525: 467:high cholesterol 332:, which prevent 239:edit on Wikidata 236: 157:Accelerans nerve 62: 50: 49: 21: 11203: 11202: 11198: 11197: 11196: 11194: 11193: 11192: 11183:Cardiac anatomy 11168: 11167: 11166: 11157: 11075: 11025: 10987: 10984:Vascular system 10974: 10958: 10895: 10797: 10782:(Contractility) 10741: 10693: 10684:Wiggers diagram 10597: 10592: 10562: 10557: 10527: 10485: 10467: 10461:Purkinje fibers 10456:bundle branches 10412: 10383: 10341:pulmonary veins 10325: 10309:pulmonary valve 10293:right ventricle 10289:tricuspid valve 10220: 10202: 10154:terminal sulcus 10123: 10053: 10049:Anatomy of the 10047: 10002: 9953: 9943: 9924: 9905: 9886: 9868: 9863: 9862: 9851: 9835: 9831: 9821: 9819: 9818:on 29 July 2016 9806: 9805: 9801: 9793: 9789: 9778: 9762: 9755: 9744: 9728: 9724: 9713: 9697: 9693: 9682: 9666: 9659: 9648: 9632: 9628: 9618: 9616: 9606: 9602: 9592: 9590: 9586: 9553: 9547: 9543: 9533: 9531: 9527: 9496: 9490: 9486: 9475: 9459: 9455: 9418: 9411: 9400: 9384: 9377: 9370: 9350: 9346: 9339: 9325: 9310: 9300: 9298: 9291: 9275: 9271: 9260: 9244: 9240: 9201: 9197: 9181: 9177: 9160: 9156: 9142: 9138: 9121: 9117: 9110: 9085: 9081: 9065: 9061: 9041: 9037: 9020: 9016: 9004: 9000: 8989: 8985: 8975: 8973: 8965: 8964: 8960: 8950: 8948: 8940: 8939: 8935: 8925: 8923: 8915: 8914: 8910: 8900: 8898: 8890: 8889: 8885: 8869: 8868: 8864: 8850: 8846: 8839: 8825: 8821: 8811: 8809: 8799: 8795: 8785: 8783: 8773: 8769: 8759: 8757: 8749: 8748: 8744: 8734: 8732: 8731:. 20 April 2020 8723: 8722: 8715: 8698: 8694: 8682: 8678: 8653: 8649: 8642: 8628: 8624: 8613: 8591: 8587: 8580: 8566: 8562: 8546: 8545: 8538: 8536: 8529: 8513: 8509: 8503:Wayback Machine 8493: 8489: 8482: 8468: 8464: 8457: 8443: 8439: 8429: 8427: 8421:"Mummification" 8419: 8418: 8414: 8407: 8393: 8389: 8376:Wayback Machine 8361: 8357: 8350: 8336: 8332: 8325: 8311: 8302: 8261: 8257: 8247: 8245: 8237: 8236: 8232: 8199: 8195: 8158: 8154: 8147: 8135: 8134: 8130: 8120: 8118: 8109: 8108: 8104: 8051: 8047: 8008: 8004: 7996: 7955: 7949: 7942: 7901: 7897: 7850: 7846: 7807: 7803: 7758: 7741: 7704: 7700: 7653: 7642: 7632: 7630: 7617: 7616: 7607: 7601:Davidson's 2010 7599: 7595: 7550: 7543: 7533: 7531: 7494:Atherosclerosis 7486: 7482: 7471: 7455: 7451: 7445:Davidson's 2010 7443: 7432: 7426:Davidson's 2010 7424: 7420: 7416:, p. 1534. 7414:Harrison's 2011 7412: 7408: 7404:, pp. 531. 7402:Davidson's 2010 7400: 7396: 7386: 7384: 7369: 7365: 7359:Davidson's 2010 7357: 7350: 7343: 7329: 7322: 7316:Davidson's 2010 7314: 7305: 7298: 7284: 7280: 7274:Davidson's 2010 7272: 7268: 7258: 7256: 7254:medlineplus.gov 7248: 7247: 7243: 7187: 7183: 7173: 7171: 7169:medlineplus.gov 7163: 7162: 7158: 7148: 7146: 7144:medlineplus.gov 7138: 7137: 7133: 7123: 7121: 7113: 7112: 7108: 7073:Heart Lung Circ 7069: 7065: 7038: 7034: 7003:10.1038/415213a 6975: 6971: 6965:Harrison's 2011 6963: 6959: 6913: 6909: 6903:Davidson's 2010 6901: 6897: 6852: 6848: 6802: 6793: 6748: 6741: 6735:Davidson's 2010 6733: 6729: 6684: 6677: 6667: 6665: 6661: 6606: 6600: 6587: 6581:Davidson's 2010 6579: 6575: 6571:, p. 1501. 6569:Harrison's 2011 6567: 6563: 6553: 6551: 6538: 6537: 6530: 6520: 6518: 6505: 6504: 6500: 6490: 6488: 6475: 6474: 6465: 6457: 6453: 6445: 6441: 6434: 6420: 6416: 6408: 6389: 6383: 6379: 6342: 6338: 6330: 6326: 6316: 6314: 6305: 6304: 6300: 6290: 6288: 6279: 6278: 6274: 6235: 6231: 6194: 6190: 6183: 6169: 6165: 6158: 6144: 6137: 6114: 6107: 6099: 6095: 6089:Wayback Machine 6079: 6075: 6059: 6055: 6031:10.1.1.860.9613 6014: 6010: 6000: 5998: 5989: 5988: 5984: 5976: 5972: 5966:Davidson's 2010 5964: 5960: 5952: 5945: 5937: 5933: 5927:Davidson's 2010 5925: 5921: 5905: 5904: 5892: 5878: 5874: 5866: 5862: 5807: 5803: 5755: 5751: 5741: 5739: 5726: 5725: 5721: 5711: 5709: 5700: 5699: 5695: 5685: 5683: 5668: 5664: 5656: 5652: 5644: 5635: 5628: 5614: 5610: 5602: 5598: 5590: 5583: 5535: 5531: 5521: 5519: 5518:on 29 July 2016 5504: 5500: 5493: 5479: 5475: 5465: 5463: 5454: 5453: 5449: 5439: 5437: 5433: 5400: 5393: 5389: 5382: 5368: 5359: 5349: 5347: 5334: 5333: 5324: 5316: 5312: 5304: 5295: 5287: 5283: 5236: 5232: 5183: 5179: 5169: 5167: 5160: 5144: 5007: 4999: 4992: 4981: 4965: 4958: 4947: 4931: 4927: 4920: 4906: 4897: 4889: 4885: 4878: 4864: 4860: 4843: 4838: 4833: 4829: 4820: 4816: 4811: 4807: 4802: 4798: 4793: 4789: 4784: 4780: 4775: 4771: 4766: 4762: 4758: 4751: 4748: 4739: 4736: 4727: 4724: 4715: 4712: 4703: 4697: 4688: 4685: 4676: 4673: 4664: 4598:, copper-based 4535: 4519:ray-finned fish 4508:ascending aorta 4469: 4461: 4455: 4427: 4371: 4343: 4333: 4281: 4276: 4270: 4130: 4107:Valentine's Day 4085:The notion of " 3953:small intestine 3822:Judeo-Christian 3806: 3805: 3804: 3803: 3802: 3788: 3780: 3779: 3776:Georgian script 3768: 3760: 3759: 3753: 3742: 3717: 3687: 3673: 3614:cardiac surgery 3583:sinoatrial node 3549:Purkinje fibers 3538:Ernest Starling 3512: 3455: 3405: 3400: 3353: 3347: 3248: 3236:Main articles: 3234: 3205: 3199: 3136: 3124:Main articles: 3122: 3114: 3071:transesophageal 3031: 3029:Cardiac imaging 3025: 2992:, or earthed). 2974: 2968: 2910:is a sensitive 2902: 2845: 2844: 2836: 2834: 2833: 2832: 2831: 2825: 2818: 2815: 2808: 2802: 2790: 2780: 2732: 2724:Main articles: 2722: 2702:echocardiograms 2690:medical history 2686: 2615:Channelopathies 2612: 2606: 2604:Channelopathies 2559: 2553: 2529:cytomegalovirus 2525:glandular fever 2517: 2442: 2436: 2404: 2403: 2395: 2393: 2392: 2391: 2390: 2386: 2378: 2375: 2368: 2362: 2357: 2351: 2323: 2317: 2281: 2275: 2261:, uncontrolled 2247:unstable angina 2234:atherosclerosis 2230: 2224: 2181: 2180: 2179: 2178: 2177: 2170:angina pectoris 2158:Atherosclerosis 2155: 2146: 2145: 2144: 2129: 2118: 2113: 2046: 1963:sinoatrial node 1942: 1941: 1933: 1931: 1930: 1929: 1928: 1925: 1917: 1914: 1907: 1901: 1896: 1890: 1874:Purkinje fibers 1870:bundle branches 1841:sinoatrial node 1821: 1815: 1793:agents such as 1707: 1701: 1660: 1648:Main articles: 1646: 1602:tricuspid valve 1534: 1519: 1509: 1504: 1496: 1425: 1417:Main articles: 1413: 1405:beta–1 receptor 1390:(also known as 1332: 1242: 1228: 1214: 1208: 1174:. They include 1149:autorhythmicity 1121:pacemaker cells 1052: 1046: 1007:pulmonary veins 996: 988:pulmonary trunk 934:tricuspid valve 930: 910:pulmonary valve 886:tricuspid valve 867:tricuspid valve 855: 854: 853: 852: 851: 848: 840: 839: 836: 825: 819: 765:coronary sulcus 737: 701:midsternal line 693:pulmonary trunk 622: 620: 615: 594: 573: 568: 567: 559: 557: 556: 555: 554: 547: 539: 536: 529: 523: 487:medical history 377:sinoatrial node 373:pacemaker cells 283:metabolic waste 243: 190:ÎșÎ±ÏÎŽÎŻÎ± (kardĂ­a) 129:pulmonary veins 97:pulmonary trunk 65: 64:The human heart 46: 35: 28: 23: 22: 15: 12: 11: 5: 11201: 11191: 11190: 11185: 11180: 11163: 11162: 11159: 11158: 11156: 11155: 11154: 11153: 11148: 11143: 11133: 11132: 11131: 11126: 11121: 11114:Autoregulation 11111: 11106: 11101: 11096: 11091: 11085: 11083: 11077: 11076: 11074: 11073: 11068: 11063: 11058: 11053: 11052: 11051: 11046: 11039:Pulse pressure 11035: 11033: 11031:Blood pressure 11027: 11026: 11024: 11023: 11018: 11013: 11008: 11002: 11000: 10991: 10980: 10979: 10976: 10975: 10973: 10972: 10966: 10964: 10960: 10959: 10957: 10956: 10951: 10950: 10949: 10944: 10936: 10935: 10934: 10924: 10923: 10922: 10917: 10909: 10907:Central venous 10903: 10901: 10897: 10896: 10894: 10893: 10888: 10887: 10886: 10881: 10876: 10871: 10866: 10861: 10856: 10846: 10841: 10836: 10835: 10834: 10829: 10824: 10816: 10811: 10805: 10803: 10799: 10798: 10796: 10795: 10789: 10788:(Excitability) 10783: 10777: 10767: 10757: 10751: 10749: 10743: 10742: 10740: 10739: 10734: 10729: 10724: 10719: 10713: 10703: 10701: 10695: 10694: 10692: 10691: 10686: 10681: 10676: 10671: 10666: 10661: 10656: 10655: 10654: 10649: 10639: 10638: 10637: 10632: 10625:Cardiac output 10622: 10616: 10614: 10612:Cardiac output 10605: 10599: 10598: 10591: 10590: 10583: 10576: 10568: 10559: 10558: 10556: 10555: 10550: 10545: 10539: 10537: 10533: 10532: 10529: 10528: 10526: 10525: 10520: 10519: 10518: 10508: 10507: 10506: 10495: 10493: 10487: 10486: 10484: 10483: 10477: 10475: 10469: 10468: 10466: 10465: 10464: 10463: 10458: 10453: 10448: 10443: 10438: 10433: 10422: 10420: 10414: 10413: 10411: 10410: 10404: 10402: 10393: 10389: 10388: 10385: 10384: 10382: 10381: 10359:left ventricle 10335: 10333: 10327: 10326: 10324: 10323: 10255:coronary sinus 10245: 10243: 10234: 10230: 10229: 10226: 10225: 10222: 10221: 10219: 10218: 10213: 10207: 10204: 10203: 10201: 10200: 10195: 10190: 10185: 10184: 10183: 10178: 10173: 10168: 10158: 10157: 10156: 10151: 10146: 10135: 10129: 10125: 10124: 10122: 10121: 10120: 10119: 10114: 10106: 10105: 10104: 10099: 10094: 10089: 10079: 10074: 10068: 10066: 10059: 10055: 10054: 10046: 10045: 10038: 10031: 10023: 10017: 10016: 10000: 9999:, 1 June 2006) 9990: 9985: 9980: 9975: 9970: 9964: 9959: 9952: 9951:External links 9949: 9948: 9947: 9941: 9928: 9922: 9909: 9903: 9890: 9884: 9867: 9864: 9861: 9860: 9849: 9829: 9799: 9787: 9776: 9753: 9742: 9722: 9711: 9691: 9680: 9657: 9646: 9626: 9600: 9564:(2): 359–365. 9541: 9507:(3): 381–392. 9484: 9473: 9453: 9409: 9398: 9375: 9368: 9344: 9337: 9308: 9289: 9269: 9258: 9238: 9211:(8): 590–597. 9195: 9175: 9154: 9136: 9115: 9108: 9079: 9059: 9043:Kennedy, Diana 9035: 9014: 8998: 8995:. p. 125. 8983: 8958: 8933: 8908: 8883: 8862: 8844: 8837: 8819: 8793: 8767: 8742: 8713: 8692: 8676: 8647: 8640: 8622: 8611: 8585: 8578: 8560: 8527: 8507: 8487: 8480: 8462: 8455: 8437: 8412: 8405: 8387: 8355: 8348: 8330: 8323: 8300: 8255: 8230: 8211:(1): 189–205. 8193: 8172:(4): 353–357. 8152: 8145: 8137:Organ Donation 8128: 8102: 8045: 8002: 7940: 7913:(3): 468–470. 7895: 7844: 7823:(1): 109–114. 7801: 7739: 7698: 7640: 7605: 7593: 7564:(4): 517–592. 7541: 7480: 7469: 7449: 7430: 7418: 7406: 7394: 7363: 7348: 7341: 7320: 7303: 7296: 7278: 7266: 7241: 7181: 7156: 7131: 7106: 7063: 7032: 6969: 6957: 6907: 6895: 6846: 6791: 6739: 6727: 6675: 6617:(8): 891–975. 6585: 6583:, p. 554. 6573: 6561: 6528: 6498: 6463: 6461:, p. 212. 6451: 6449:, p. 208. 6439: 6432: 6414: 6377: 6356:(4): 619–626. 6336: 6324: 6298: 6272: 6229: 6188: 6181: 6163: 6156: 6135: 6105: 6093: 6073: 6053: 6024:(3): 151–157. 6008: 5982: 5980:, p. 945. 5970: 5968:, p. 526. 5958: 5956:, p. 982. 5943: 5941:, p. 981. 5931: 5929:, p. 525. 5919: 5890: 5872: 5870:, p. 959. 5860: 5801: 5749: 5719: 5693: 5662: 5660:, p. 970. 5650: 5633: 5626: 5608: 5596: 5581: 5529: 5498: 5491: 5473: 5447: 5387: 5380: 5357: 5322: 5310: 5293: 5281: 5230: 5193:(2): 193–216. 5187:Animal Biology 5177: 5158: 5005: 5003:, p. 960. 4990: 4979: 4956: 4945: 4925: 4918: 4895: 4893:, p. 157. 4883: 4876: 4857: 4856: 4842: 4839: 4837: 4836: 4827: 4814: 4805: 4796: 4787: 4778: 4769: 4759: 4757: 4754: 4753: 4752: 4749: 4742: 4740: 4737: 4730: 4728: 4725: 4718: 4716: 4713: 4706: 4704: 4698: 4691: 4689: 4686: 4679: 4677: 4674: 4667: 4663: 4660: 4534: 4531: 4488:cardinal veins 4467: 4457:Main article: 4454: 4451: 4426: 4423: 4396:blood pressure 4370: 4369: 4366: 4363: 4360: 4357: 4354: 4353:Pulmonary vein 4350: 4332: 4329: 4280: 4277: 4269: 4266: 4129: 4126: 3959:, governs the 3796:Middle Chinese 3789: 3782: 3781: 3769: 3762: 3761: 3754: 3747: 3746: 3745: 3744: 3743: 3741: 3738: 3735: 3734: 3731: 3730: 3727: 3726: 3723: 3722: 3710: 3709: 3706: 3705: 3702: 3701: 3672: 3669: 3661:ACE inhibitors 3622:Norman Shumway 3530:William Harvey 3525:De Motu Cordis 3518:Animated heart 3511: 3508: 3454: 3451: 3421:ancient Greeks 3415:, 15th century 3404: 3401: 3399: 3396: 3373:ACE inhibitors 3349:Main article: 3346: 3343: 3233: 3230: 3201:Main article: 3198: 3195: 3179:saphenous vein 3134:Coronary stent 3121: 3118: 3113: 3110: 3027:Main article: 3024: 3021: 3017:Holter monitor 2970:Main article: 2967: 2964: 2948:Fasting lipids 2901: 2898: 2865:gallop rhythms 2835: 2826: 2816: 2811: 2810: 2809: 2800: 2799: 2798: 2779: 2776: 2756:blood pressure 2721: 2718: 2685: 2682: 2681: 2680: 2674: 2660: 2654: 2648: 2642: 2608:Main article: 2605: 2602: 2555:Main article: 2552: 2549: 2533:coxsackievirus 2516: 2513: 2485:atrial flutter 2438:Main article: 2435: 2432: 2394: 2387: 2376: 2371: 2370: 2369: 2360: 2359: 2358: 2353:Main article: 2350: 2347: 2321:Cardiomyopathy 2319:Main article: 2316: 2313: 2277:Main article: 2274: 2271: 2251:cardiac arrest 2226:Main article: 2223: 2220: 2168:are affected, 2156: 2149: 2148: 2147: 2130: 2123: 2122: 2121: 2120: 2119: 2117: 2114: 2112: 2109: 2101:blood pressure 2074:carotid bodies 2063:chemoreceptors 2045: 2042: 2010:repolarisation 1986:depolarisation 1957:is called the 1932: 1926: 1915: 1910: 1909: 1908: 1899: 1898: 1897: 1892:Main article: 1889: 1886: 1817:Main article: 1814: 1811: 1731:echocardiogram 1705:Cardiac output 1703:Main article: 1700: 1699:Cardiac output 1697: 1645: 1642: 1598:coronary sinus 1567:carbon dioxide 1508: 1505: 1500:Main article: 1495: 1492: 1412: 1409: 1388:norepinephrine 1372:cardiac plexus 1331: 1328: 1292:coronary sinus 1238:Main article: 1227: 1224: 1210:Main article: 1207: 1204: 1137:major arteries 1102:cardiac muscle 1050:Cardiac muscle 1045: 1042: 1026:moderator band 995: 992: 983:moderator band 956:coronary sinus 929: 926: 849: 842: 841: 837: 830: 829: 828: 827: 826: 821:Main article: 818: 815: 736: 733: 681:rib cartilages 619: 616: 572: 569: 558: 548: 537: 532: 531: 530: 521: 520: 519: 507:echocardiogram 383:and along the 287:carbon dioxide 257:found in most 253:is a muscular 245: 244: 235: 229: 228: 223: 217: 216: 211: 205: 204: 199: 193: 192: 187: 181: 180: 175: 169: 168: 164: 163: 154: 148: 147: 118: 112: 111: 90: 84: 83: 78: 72: 71: 67: 66: 63: 55: 54: 26: 9: 6: 4: 3: 2: 11200: 11189: 11186: 11184: 11181: 11179: 11176: 11175: 11173: 11152: 11149: 11147: 11144: 11142: 11139: 11138: 11137: 11134: 11130: 11127: 11125: 11122: 11120: 11117: 11116: 11115: 11112: 11110: 11107: 11105: 11102: 11100: 11097: 11095: 11092: 11090: 11087: 11086: 11084: 11082: 11078: 11072: 11069: 11067: 11064: 11062: 11059: 11057: 11054: 11050: 11047: 11045: 11042: 11041: 11040: 11037: 11036: 11034: 11032: 11028: 11022: 11019: 11017: 11014: 11012: 11009: 11007: 11004: 11003: 11001: 10999: 10995: 10992: 10990: 10985: 10981: 10971: 10968: 10967: 10965: 10961: 10955: 10952: 10948: 10945: 10943: 10940: 10939: 10937: 10933: 10930: 10929: 10928: 10925: 10921: 10918: 10916: 10913: 10912: 10910: 10908: 10905: 10904: 10902: 10898: 10892: 10889: 10885: 10882: 10880: 10877: 10875: 10872: 10870: 10867: 10865: 10862: 10860: 10857: 10855: 10852: 10851: 10850: 10847: 10845: 10842: 10840: 10837: 10833: 10830: 10828: 10825: 10823: 10820: 10819: 10817: 10815: 10812: 10810: 10807: 10806: 10804: 10800: 10793: 10790: 10787: 10784: 10781: 10778: 10775: 10771: 10768: 10765: 10761: 10758: 10756: 10753: 10752: 10750: 10748: 10744: 10738: 10735: 10733: 10732:Cardiac index 10730: 10728: 10725: 10723: 10720: 10717: 10714: 10712: 10708: 10705: 10704: 10702: 10700: 10696: 10690: 10687: 10685: 10682: 10680: 10677: 10675: 10672: 10670: 10667: 10665: 10662: 10660: 10657: 10653: 10650: 10648: 10645: 10644: 10643: 10642:Stroke volume 10640: 10636: 10635:Stroke volume 10633: 10631: 10628: 10627: 10626: 10623: 10621: 10620:Cardiac cycle 10618: 10617: 10615: 10613: 10609: 10606: 10604: 10600: 10596: 10589: 10584: 10582: 10577: 10575: 10570: 10569: 10566: 10554: 10551: 10549: 10546: 10544: 10541: 10540: 10538: 10534: 10524: 10521: 10517: 10514: 10513: 10512: 10509: 10505: 10502: 10501: 10500: 10497: 10496: 10494: 10492: 10488: 10482: 10479: 10478: 10476: 10474: 10470: 10462: 10459: 10457: 10454: 10452: 10451:bundle of His 10449: 10447: 10444: 10442: 10439: 10437: 10434: 10432: 10429: 10428: 10427: 10424: 10423: 10421: 10419: 10415: 10409: 10406: 10405: 10403: 10401: 10397: 10394: 10390: 10380: 10378: 10374: 10368: 10364: 10360: 10356: 10352: 10348: 10344: 10342: 10337: 10336: 10334: 10332: 10328: 10322: 10320: 10316: 10310: 10306: 10302: 10298: 10294: 10290: 10286: 10282: 10278: 10274: 10270: 10266: 10262: 10258: 10256: 10252: 10247: 10246: 10244: 10242: 10238: 10235: 10231: 10217: 10214: 10212: 10209: 10208: 10205: 10199: 10196: 10194: 10191: 10189: 10186: 10182: 10179: 10177: 10174: 10172: 10169: 10167: 10164: 10163: 10162: 10159: 10155: 10152: 10150: 10147: 10145: 10142: 10141: 10140: 10137: 10136: 10133: 10130: 10126: 10118: 10115: 10113: 10110: 10109: 10107: 10103: 10100: 10098: 10095: 10093: 10090: 10088: 10085: 10084: 10083: 10080: 10078: 10075: 10073: 10070: 10069: 10067: 10063: 10060: 10056: 10052: 10044: 10039: 10037: 10032: 10030: 10025: 10024: 10021: 10013: 10012: 10006: 10005:"Heart"  10001: 9998: 9994: 9991: 9989: 9986: 9984: 9981: 9979: 9976: 9974: 9971: 9968: 9965: 9963: 9960: 9958: 9955: 9954: 9944: 9938: 9934: 9929: 9925: 9919: 9915: 9910: 9906: 9900: 9896: 9891: 9887: 9881: 9877: 9876: 9870: 9869: 9856: 9852: 9846: 9842: 9841: 9833: 9817: 9813: 9809: 9803: 9797: 9791: 9783: 9779: 9773: 9769: 9768: 9760: 9758: 9749: 9745: 9739: 9735: 9734: 9730:Shukla, J.P. 9726: 9718: 9714: 9708: 9704: 9703: 9695: 9687: 9683: 9677: 9673: 9672: 9664: 9662: 9653: 9649: 9643: 9639: 9638: 9630: 9615: 9611: 9604: 9585: 9581: 9577: 9572: 9567: 9563: 9559: 9552: 9545: 9526: 9522: 9518: 9514: 9510: 9506: 9502: 9495: 9488: 9480: 9476: 9470: 9466: 9465: 9457: 9449: 9445: 9440: 9435: 9432:(1): 97–109. 9431: 9427: 9423: 9416: 9414: 9405: 9401: 9395: 9391: 9390: 9382: 9380: 9371: 9365: 9361: 9357: 9356: 9348: 9340: 9334: 9330: 9323: 9321: 9319: 9317: 9315: 9313: 9296: 9292: 9286: 9282: 9281: 9273: 9265: 9261: 9255: 9251: 9250: 9242: 9234: 9230: 9226: 9222: 9218: 9214: 9210: 9206: 9199: 9193: 9192:1-4027-7050-2 9189: 9185: 9179: 9172: 9171:1-60085-126-6 9168: 9164: 9158: 9151: 9150: 9145: 9140: 9133: 9132:0-8139-1162-1 9129: 9125: 9119: 9111: 9105: 9101: 9096: 9095: 9089: 9083: 9077: 9076:1-55970-174-9 9073: 9069: 9063: 9056: 9055:0-292-74840-X 9052: 9048: 9044: 9039: 9032: 9031:977-424-926-7 9028: 9024: 9018: 9012:(1994), p. 67 9011: 9007: 9002: 8994: 8987: 8972: 8971:Bible Gateway 8968: 8962: 8947: 8946:Bible Gateway 8943: 8937: 8922: 8921:Bible Gateway 8918: 8912: 8897: 8896:Bible Gateway 8893: 8887: 8879: 8873: 8865: 8859: 8855: 8848: 8840: 8834: 8830: 8823: 8808: 8804: 8797: 8782: 8778: 8771: 8756: 8752: 8746: 8730: 8726: 8720: 8718: 8710: 8709:0-8061-2403-2 8706: 8702: 8696: 8689: 8685: 8680: 8673: 8667: 8663: 8662: 8657: 8651: 8643: 8637: 8633: 8626: 8618: 8614: 8608: 8604: 8600: 8598: 8589: 8581: 8575: 8571: 8564: 8556: 8550: 8534: 8530: 8524: 8520: 8519: 8511: 8504: 8500: 8497: 8491: 8483: 8477: 8473: 8466: 8458: 8452: 8448: 8441: 8426: 8422: 8416: 8408: 8402: 8398: 8391: 8385: 8381: 8377: 8373: 8370: 8369: 8365: 8359: 8351: 8345: 8341: 8334: 8326: 8320: 8316: 8309: 8307: 8305: 8296: 8292: 8288: 8284: 8280: 8276: 8272: 8268: 8267: 8259: 8244: 8240: 8234: 8226: 8222: 8218: 8214: 8210: 8206: 8205: 8197: 8189: 8185: 8180: 8175: 8171: 8167: 8163: 8156: 8148: 8146:9780737762693 8142: 8138: 8132: 8116: 8112: 8106: 8098: 8094: 8089: 8084: 8080: 8076: 8072: 8068: 8064: 8060: 8056: 8049: 8041: 8037: 8032: 8027: 8023: 8019: 8018: 8013: 8006: 7995: 7991: 7987: 7983: 7979: 7975: 7971: 7967: 7963: 7962: 7954: 7947: 7945: 7936: 7932: 7928: 7924: 7920: 7916: 7912: 7908: 7907: 7899: 7891: 7887: 7882: 7877: 7873: 7869: 7865: 7861: 7860: 7855: 7848: 7840: 7836: 7831: 7826: 7822: 7818: 7817: 7812: 7805: 7797: 7793: 7789: 7785: 7780: 7775: 7771: 7767: 7763: 7756: 7754: 7752: 7750: 7748: 7746: 7744: 7735: 7731: 7726: 7721: 7717: 7713: 7709: 7702: 7694: 7690: 7685: 7680: 7675: 7670: 7666: 7662: 7658: 7651: 7649: 7647: 7645: 7628: 7624: 7620: 7614: 7612: 7610: 7602: 7597: 7589: 7585: 7581: 7577: 7572: 7567: 7563: 7559: 7555: 7548: 7546: 7529: 7525: 7521: 7517: 7513: 7508: 7503: 7499: 7495: 7491: 7484: 7476: 7472: 7466: 7462: 7461: 7453: 7446: 7441: 7439: 7437: 7435: 7427: 7422: 7415: 7410: 7403: 7398: 7382: 7378: 7374: 7367: 7360: 7355: 7353: 7344: 7338: 7334: 7327: 7325: 7317: 7312: 7310: 7308: 7299: 7293: 7289: 7282: 7275: 7270: 7255: 7251: 7245: 7237: 7233: 7228: 7223: 7219: 7215: 7210: 7205: 7201: 7197: 7193: 7185: 7170: 7166: 7160: 7145: 7141: 7135: 7120: 7116: 7110: 7102: 7098: 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6233: 6225: 6221: 6216: 6211: 6207: 6203: 6199: 6192: 6184: 6178: 6174: 6167: 6159: 6153: 6149: 6142: 6140: 6131: 6127: 6123: 6119: 6112: 6110: 6102: 6097: 6090: 6086: 6083: 6077: 6071: 6070:0-7216-5432-0 6067: 6063: 6057: 6049: 6045: 6041: 6037: 6032: 6027: 6023: 6019: 6012: 5996: 5992: 5986: 5979: 5974: 5967: 5962: 5955: 5950: 5948: 5940: 5935: 5928: 5923: 5915: 5909: 5901: 5897: 5893: 5887: 5883: 5876: 5869: 5864: 5856: 5852: 5847: 5842: 5838: 5834: 5829: 5824: 5820: 5816: 5812: 5805: 5797: 5793: 5789: 5785: 5781: 5777: 5773: 5769: 5765: 5761: 5753: 5737: 5733: 5729: 5723: 5707: 5703: 5697: 5681: 5677: 5673: 5666: 5659: 5654: 5647: 5642: 5640: 5638: 5629: 5623: 5619: 5612: 5605: 5600: 5593: 5588: 5586: 5577: 5573: 5569: 5565: 5561: 5557: 5553: 5549: 5545: 5541: 5533: 5517: 5513: 5512:HowStuffWorks 5509: 5502: 5494: 5488: 5484: 5477: 5461: 5457: 5451: 5432: 5428: 5424: 5419: 5414: 5410: 5406: 5399: 5391: 5383: 5377: 5373: 5366: 5364: 5362: 5345: 5341: 5337: 5331: 5329: 5327: 5319: 5314: 5307: 5302: 5300: 5298: 5290: 5285: 5277: 5273: 5268: 5263: 5258: 5253: 5249: 5245: 5241: 5234: 5226: 5222: 5218: 5214: 5210: 5206: 5201: 5196: 5192: 5188: 5181: 5165: 5161: 5155: 5151: 5150: 5142: 5140: 5138: 5136: 5134: 5132: 5130: 5128: 5126: 5124: 5122: 5120: 5118: 5116: 5114: 5112: 5110: 5108: 5106: 5104: 5102: 5100: 5098: 5096: 5094: 5092: 5090: 5088: 5086: 5084: 5082: 5080: 5078: 5076: 5074: 5072: 5070: 5068: 5066: 5064: 5062: 5060: 5058: 5056: 5054: 5052: 5050: 5048: 5046: 5044: 5042: 5040: 5038: 5036: 5034: 5032: 5030: 5028: 5026: 5024: 5022: 5020: 5018: 5016: 5014: 5012: 5010: 5002: 4997: 4995: 4986: 4982: 4976: 4972: 4971: 4963: 4961: 4952: 4948: 4942: 4938: 4937: 4929: 4921: 4915: 4911: 4904: 4902: 4900: 4892: 4887: 4879: 4873: 4869: 4862: 4858: 4855: 4854: 4853: 4849: 4831: 4824: 4818: 4809: 4800: 4791: 4782: 4773: 4764: 4760: 4746: 4741: 4734: 4729: 4722: 4717: 4710: 4705: 4702: 4695: 4690: 4683: 4678: 4671: 4666: 4665: 4659: 4657: 4653: 4649: 4645: 4644:hemichordates 4641: 4636: 4634: 4630: 4626: 4622: 4620: 4612: 4609:Schematic of 4607: 4603: 4601: 4597: 4593: 4589: 4585: 4581: 4577: 4570: 4565: 4558: 4554: 4550: 4546: 4545: 4539: 4533:Invertebrates 4530: 4528: 4524: 4520: 4516: 4511: 4509: 4505: 4501: 4497: 4496:ventral aorta 4493: 4489: 4485: 4481: 4480:sinus venosus 4475: 4465: 4460: 4450: 4448: 4443: 4439: 4435: 4431: 4425:Full division 4422: 4420: 4416: 4412: 4407: 4405: 4401: 4397: 4393: 4388: 4386: 4382: 4378: 4368:Sinus venosus 4367: 4364: 4361: 4358: 4355: 4352: 4351: 4347: 4342: 4338: 4328: 4326: 4322: 4318: 4313: 4308: 4303: 4301: 4297: 4293: 4289: 4286: 4275: 4268:Other animals 4265: 4263: 4259: 4255: 4254:blood sausage 4252:is a sort of 4251: 4248: 4244: 4240: 4238: 4234: 4230: 4229: 4225: 4221: 4217: 4215: 4211: 4205: 4203: 4200: 4196: 4193: 4189: 4185: 4181: 4177: 4174: 4170: 4169: 4165: 4161: 4160: 4159:hāto yakitori 4156: 4152: 4148: 4144: 4142: 4139: 4135: 4125: 4123: 4119: 4115: 4110: 4108: 4104: 4100: 4099:heart symbols 4096: 4092: 4088: 4083: 4081: 4080:romantic love 4077: 4073: 4068: 4066: 4062: 4058: 4054: 4050: 4046: 4041: 4039: 4033: 4031: 4027: 4023: 4019: 4014: 4012: 4008: 4004: 4000: 3996: 3992: 3988: 3983: 3981: 3977: 3973: 3969: 3964: 3962: 3958: 3954: 3950: 3949: 3943: 3939: 3938: 3933: 3929: 3924: 3922: 3918: 3914: 3910: 3906: 3901: 3897: 3893: 3889: 3885: 3881: 3877: 3873: 3869: 3865: 3861: 3856: 3854: 3850: 3845: 3843: 3839: 3835: 3831: 3827: 3823: 3814: 3810: 3800: 3797: 3793: 3786: 3777: 3773: 3766: 3758: 3751: 3733: 3732: 3729: 3728: 3725: 3724: 3721: 3716:(F34) "heart" 3715: 3712: 3711: 3699: 3698: 3695: 3694: 3691: 3690: 3686: 3682: 3678: 3668: 3666: 3665:beta blockers 3662: 3658: 3654: 3653:heart disease 3649: 3647: 3643: 3639: 3635: 3631: 3627: 3626:Richard Lower 3623: 3619: 3615: 3611: 3607: 3603: 3599: 3595: 3590: 3588: 3584: 3580: 3576: 3572: 3568: 3567: 3562: 3558: 3554: 3553:bundle of His 3550: 3545: 3543: 3539: 3535: 3531: 3527: 3526: 3516: 3507: 3505: 3504: 3499: 3495: 3491: 3490: 3485: 3480: 3478: 3477:Andrea Alpago 3474: 3470: 3466: 3465: 3460: 3450: 3447: 3445: 3440: 3438: 3434: 3430: 3426: 3422: 3414: 3409: 3395: 3393: 3389: 3385: 3380: 3378: 3374: 3370: 3369:beta blockers 3366: 3362: 3358: 3352: 3351:Heart failure 3345:Heart failure 3342: 3340: 3336: 3331: 3327: 3322: 3320: 3319:cardioversion 3316: 3315:thoracoscopic 3312: 3308: 3304: 3300: 3296: 3292: 3287: 3285: 3281: 3277: 3273: 3272:beta blockers 3269: 3265: 3261: 3257: 3253: 3247: 3243: 3239: 3229: 3227: 3223: 3219: 3215: 3211: 3204: 3194: 3192: 3188: 3184: 3183:radial artery 3180: 3176: 3171: 3169: 3164: 3162: 3158: 3154: 3153:antiplatelets 3150: 3149:beta blockers 3146: 3145:nitroglycerin 3142: 3135: 3131: 3127: 3117: 3109: 3107: 3103: 3099: 3094: 3092: 3088: 3084: 3080: 3079:regurgitation 3076: 3072: 3068: 3064: 3063:transthoracic 3060: 3056: 3052: 3048: 3044: 3040: 3036: 3030: 3020: 3018: 3014: 3010: 3006: 3002: 2998: 2993: 2991: 2987: 2978: 2973: 2963: 2961: 2957: 2953: 2949: 2945: 2941: 2937: 2933: 2928: 2926: 2922: 2918: 2913: 2909: 2905: 2897: 2895: 2891: 2887: 2883: 2878: 2877:Heart murmurs 2874: 2870: 2866: 2862: 2858: 2854: 2850: 2843: 2841: 2830: 2814: 2794: 2788: 2784: 2775: 2773: 2769: 2765: 2761: 2757: 2753: 2752:radial artery 2749: 2745: 2741: 2737: 2731: 2727: 2717: 2715: 2711: 2707: 2703: 2699: 2695: 2691: 2678: 2675: 2672: 2668: 2664: 2661: 2658: 2655: 2652: 2649: 2646: 2643: 2640: 2636: 2633: 2632: 2631: 2629: 2625: 2620: 2616: 2611: 2610:Channelopathy 2601: 2599: 2595: 2591: 2586: 2584: 2580: 2576: 2572: 2568: 2564: 2558: 2548: 2546: 2542: 2538: 2534: 2530: 2526: 2522: 2512: 2510: 2506: 2502: 2498: 2494: 2490: 2486: 2482: 2478: 2474: 2470: 2465: 2463: 2459: 2455: 2451: 2447: 2441: 2431: 2429: 2428:streptococcal 2425: 2421: 2417: 2413: 2412:regurgitation 2409: 2402: 2400: 2374: 2356: 2346: 2344: 2340: 2336: 2332: 2328: 2322: 2312: 2310: 2306: 2302: 2298: 2294: 2290: 2286: 2285:heart failure 2280: 2279:Heart failure 2273:Heart failure 2270: 2268: 2264: 2260: 2256: 2252: 2248: 2244: 2239: 2235: 2229: 2219: 2217: 2213: 2209: 2205: 2201: 2197: 2193: 2192:cardiologists 2189: 2185: 2175: 2171: 2167: 2163: 2159: 2153: 2142: 2141:heart murmurs 2138: 2134: 2127: 2108: 2106: 2102: 2098: 2094: 2090: 2086: 2081: 2079: 2075: 2071: 2066: 2064: 2060: 2059:baroreceptors 2055: 2051: 2041: 2038: 2033: 2031: 2027: 2023: 2019: 2013: 2011: 2007: 2003: 2002:voltage-gated 1999: 1995: 1991: 1987: 1983: 1978: 1976: 1972: 1968: 1964: 1960: 1956: 1946: 1940: 1938: 1913: 1895: 1881: 1877: 1875: 1871: 1867: 1866:bundle of His 1863: 1859: 1855: 1851: 1846: 1842: 1838: 1830: 1825: 1820: 1810: 1808: 1804: 1800: 1799:noradrenaline 1796: 1792: 1788: 1784: 1780: 1775: 1773: 1769: 1765: 1761: 1759: 1754: 1750: 1748: 1744: 1740: 1739:contractility 1736: 1732: 1727: 1725: 1724:cardiac index 1721: 1711: 1706: 1696: 1694: 1689: 1685: 1680: 1678: 1674: 1664: 1659: 1655: 1651: 1650:Cardiac cycle 1644:Cardiac cycle 1641: 1639: 1635: 1631: 1627: 1622: 1620: 1616: 1612: 1608: 1603: 1599: 1594: 1590: 1587: 1583: 1579: 1574: 1572: 1568: 1564: 1560: 1556: 1555:flow of blood 1552: 1513: 1503: 1498: 1491: 1489: 1485: 1481: 1476: 1473: 1472:septum primum 1469: 1468:foramen ovale 1464: 1462: 1461:tubular heart 1458: 1454: 1450: 1445: 1443: 1439: 1438:embryogenesis 1429: 1424: 1420: 1415: 1408: 1406: 1402: 1397: 1393: 1392:noradrenaline 1389: 1384: 1380: 1375: 1373: 1369: 1365: 1361: 1357: 1353: 1349: 1345: 1336: 1327: 1325: 1320: 1315: 1313: 1309: 1305: 1301: 1297: 1293: 1288: 1286: 1282: 1278: 1274: 1269: 1267: 1263: 1259: 1255: 1251: 1247: 1241: 1232: 1223: 1220: 1213: 1203: 1201: 1197: 1193: 1189: 1185: 1181: 1177: 1173: 1169: 1165: 1161: 1157: 1152: 1150: 1146: 1142: 1138: 1134: 1130: 1126: 1122: 1118: 1113: 1111: 1107: 1103: 1094: 1090: 1088: 1084: 1080: 1075: 1073: 1069: 1065: 1056: 1051: 1041: 1039: 1035: 1031: 1027: 1023: 1018: 1016: 1012: 1008: 1003: 1001: 991: 989: 984: 980: 975: 973: 969: 965: 964:foramen ovale 961: 957: 953: 950: 946: 942: 937: 935: 925: 923: 919: 915: 911: 906: 902: 899: 895: 891: 887: 882: 876: 872: 868: 864: 859: 846: 834: 824: 814: 812: 808: 804: 801: 796: 794: 790: 786: 782: 778: 774: 770: 766: 762: 758: 754: 750: 741: 732: 730: 725: 721: 717: 713: 708: 706: 702: 698: 694: 690: 686: 682: 678: 674: 670: 666: 662: 659: 655: 647: 642: 635: 634:Real-time MRI 614: 588: 582: 577: 566: 564: 552: 535: 518: 516: 515:cardiologists 512: 508: 504: 500: 496: 492: 488: 484: 480: 476: 472: 468: 464: 460: 456: 452: 448: 444: 442: 438: 434: 430: 426: 422: 418: 414: 410: 406: 402: 398: 394: 390: 386: 382: 378: 374: 370: 365: 363: 359: 355: 351: 347: 343: 339: 335: 331: 327: 323: 319: 315: 310: 308: 305:, called the 304: 300: 296: 292: 288: 284: 280: 276: 272: 268: 267:blood vessels 264: 260: 256: 252: 240: 234: 230: 227: 224: 222: 218: 215: 212: 210: 206: 203: 200: 198: 194: 191: 188: 186: 182: 179: 176: 174: 170: 165: 162: 158: 155: 153: 149: 146: 142: 138: 134: 130: 126: 122: 119: 117: 113: 110: 106: 102: 98: 94: 91: 89: 85: 82: 79: 77: 73: 68: 61: 56: 51: 48: 44: 40: 33: 19: 11146:Carotid body 11109:Vasodilators 10989:hemodynamics 10794:(Relaxation) 10786:Bathmotropic 10760:Chronotropic 10602: 10536:Blood supply 10408:heart valves 10370: 10367:aortic sinus 10363:aortic valve 10355:mitral valve 10338: 10312: 10297:infundibulum 10269:fossa ovalis 10261:right atrium 10248: 10050: 10009: 9996: 9932: 9913: 9894: 9874: 9866:Bibliography 9839: 9832: 9820:. Retrieved 9816:the original 9811: 9802: 9790: 9766: 9732: 9725: 9701: 9694: 9670: 9636: 9629: 9619:16 September 9617:. Retrieved 9603: 9591:. Retrieved 9561: 9557: 9544: 9532:. Retrieved 9504: 9500: 9487: 9463: 9456: 9429: 9425: 9388: 9354: 9347: 9328: 9299:. Retrieved 9279: 9272: 9248: 9241: 9208: 9204: 9198: 9183: 9178: 9162: 9157: 9147: 9139: 9123: 9118: 9093: 9082: 9067: 9062: 9046: 9038: 9022: 9017: 9009: 9005: 9001: 8992: 8986: 8974:. Retrieved 8970: 8961: 8949:. Retrieved 8945: 8936: 8924:. Retrieved 8920: 8911: 8899:. Retrieved 8895: 8886: 8853: 8847: 8828: 8822: 8810:. Retrieved 8806: 8796: 8784:. Retrieved 8780: 8770: 8758:. Retrieved 8754: 8745: 8733:. Retrieved 8728: 8700: 8695: 8687: 8679: 8666:the original 8660: 8650: 8631: 8625: 8602: 8596: 8588: 8569: 8563: 8537:. Retrieved 8517: 8510: 8490: 8471: 8465: 8446: 8440: 8428:. Retrieved 8424: 8415: 8396: 8390: 8383: 8380:Wallis Budge 8367: 8363: 8358: 8339: 8333: 8314: 8270: 8264: 8258: 8246:. Retrieved 8242: 8233: 8208: 8202: 8196: 8169: 8165: 8155: 8136: 8131: 8119:. Retrieved 8114: 8105: 8065:(1): 49–57. 8062: 8058: 8048: 8021: 8015: 8005: 7994:the original 7965: 7959: 7910: 7904: 7898: 7863: 7857: 7847: 7820: 7814: 7804: 7769: 7765: 7718:(1): 63–71. 7715: 7711: 7701: 7664: 7660: 7631:. Retrieved 7622: 7596: 7561: 7557: 7534:11 September 7532:. Retrieved 7497: 7493: 7483: 7459: 7452: 7421: 7409: 7397: 7385:. Retrieved 7376: 7366: 7332: 7287: 7281: 7269: 7257:. Retrieved 7253: 7244: 7199: 7195: 7184: 7172:. Retrieved 7168: 7159: 7147:. Retrieved 7143: 7134: 7122:. Retrieved 7118: 7109: 7079:(1): 22–30. 7076: 7072: 7066: 7049: 7045: 7035: 6986: 6982: 6972: 6960: 6925: 6921: 6910: 6898: 6863: 6859: 6849: 6814: 6810: 6759: 6755: 6730: 6698:(4): S1–44. 6695: 6691: 6668:24 September 6666:. Retrieved 6614: 6610: 6576: 6564: 6552:. Retrieved 6543: 6519:. Retrieved 6510: 6501: 6489:. Retrieved 6480: 6454: 6442: 6423: 6417: 6396:(41): 1–16. 6393: 6380: 6353: 6349: 6339: 6327: 6315:. Retrieved 6301: 6289:. Retrieved 6275: 6242: 6238: 6232: 6205: 6201: 6191: 6172: 6166: 6147: 6125: 6121: 6096: 6076: 6061: 6056: 6021: 6017: 6011: 5999:. Retrieved 5985: 5973: 5961: 5934: 5922: 5881: 5875: 5863: 5818: 5815:BMC Genomics 5814: 5804: 5763: 5759: 5752: 5742:29 September 5740:. Retrieved 5731: 5722: 5710:. Retrieved 5696: 5684:. Retrieved 5675: 5665: 5653: 5617: 5611: 5599: 5543: 5539: 5532: 5520:. Retrieved 5516:the original 5511: 5501: 5482: 5476: 5464:. Retrieved 5450: 5438:. Retrieved 5408: 5404: 5390: 5371: 5350:20 September 5348:. Retrieved 5339: 5313: 5284: 5247: 5243: 5233: 5190: 5186: 5180: 5168:. Retrieved 5148: 4969: 4935: 4928: 4909: 4886: 4867: 4861: 4845: 4844: 4830: 4822: 4817: 4808: 4799: 4790: 4781: 4772: 4763: 4637: 4623: 4616: 4574: 4549:wing muscles 4542: 4512: 4500:dorsal aorta 4495: 4476: 4472: 4434:crocodilians 4428: 4408: 4389: 4374: 4359:Right atrium 4321:hummingbirds 4304: 4282: 4261: 4249: 4241: 4227: 4218: 4206: 4201: 4194: 4167: 4158: 4145: 4131: 4111: 4094: 4084: 4072:broken heart 4069: 4049:Jesus Christ 4042: 4034: 4029: 4025: 4021: 4015: 3984: 3979: 3971: 3967: 3965: 3947: 3936: 3925: 3912: 3899: 3895: 3891: 3882:, will, and 3871: 3867: 3857: 3852: 3849:Hebrew Bible 3846: 3818: 3798: 3757:heart symbol 3713: 3681:Heart symbol 3677:Sacred Heart 3650: 3591: 3579:Martin Flack 3575:Arthur Keith 3564: 3561:Sunao Tawara 3546: 3523: 3521: 3501: 3487: 3481: 3469:Ibn al-Nafis 3462: 3456: 3448: 3441: 3437:Erasistratos 3418: 3381: 3361:hypertension 3354: 3323: 3288: 3249: 3206: 3172: 3165: 3137: 3115: 3098:chest X-rays 3095: 3032: 2994: 2986:bedside test 2983: 2929: 2906: 2903: 2849:heart sounds 2846: 2837: 2793:heart sounds 2778:Heart sounds 2740:auscultation 2733: 2730:Heart sounds 2687: 2667:testosterone 2613: 2587: 2560: 2521:pericarditis 2518: 2466: 2443: 2420:endocarditis 2416:heart murmur 2405: 2396: 2324: 2282: 2231: 2204:intensivists 2182: 2174:heart attack 2133:auscultation 2082: 2070:aortic sinus 2067: 2050:sinus rhythm 2047: 2034: 2014: 1998:ion channels 1979: 1975:electrolytes 1959:sinus rhythm 1952: 1934: 1845:right atrium 1837:sinus rhythm 1834: 1783:life support 1776: 1762: 1751: 1728: 1716: 1681: 1669: 1630:mitral valve 1623: 1575: 1548: 1497: 1477: 1465: 1446: 1435: 1414: 1376: 1341: 1330:Nerve supply 1316: 1289: 1270: 1243: 1215: 1153: 1117:muscle cells 1114: 1099: 1076: 1061: 1030:heart muscle 1019: 1004: 1000:mitral valve 997: 976: 960:fossa ovalis 938: 931: 918:aortic valve 907: 903: 898:mitral valve 883: 880: 871:mitral valve 823:Heart valves 807:heart valves 797: 746: 723: 709: 705:articulation 696: 651: 560: 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