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174:, the term "reagent" denotes a chemical ingredient (a compound or mixture, typically of inorganic or small organic molecules) introduced to cause the desired transformation of an organic substance. Examples include the
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Kenakin, T; Bylund, DB; Toews, ML; Mullane, K; Winquist, RJ; Williams, M (1 January 2014). "Replicated, replicable and relevant-target engagement and pharmacological experimentation in the 21st century".
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Baell, JB; Holloway, GA (8 April 2010). "New substructure filters for removal of pan assay interference compounds (PAINS) from screening libraries and for their exclusion in bioassays".
198:, a reagent is a compound or mixture used to detect the presence or absence of another substance, e.g. by a color change, or to measure the concentration of a substance, e.g. by
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However, many natural substances are hits in almost any assay in which they are tested, and therefore not useful as tool compounds. Medicinal chemists class them instead as
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revolution in the 1980s grew from the development of reagents that could be used to identify and manipulate the chemical matter in and on cells. These reagents included
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Tool compounds are an important class of reagent in biology. They are small molecules or biochemicals like
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244:, chemical reactions or physical testing. Purity standards for reagents are set by organizations such as
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Fox, Jeffrey L. (1 January 1979). "Antibody reagents revolutionizing immunology".
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pure, but still useful and economical for undemanding work, may be designated as
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or antibodies that are known to affect a given biomolecule—for example a
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52:(pictured), are the starting materials used in chemical reactions.
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are not consumed by the reaction, so they are not reactants. In
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that ensure the scientific precision and reliability of
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is a substance or compound added to a system to cause a
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Substance added to a system to cause a chemical reaction
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37:"Reactants" redirects here. Not to be confused with
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129:in the course of a chemical reaction.
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121:are often used interchangeably, but
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113:, or test if one occurs. The terms
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135:, though involved in the
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30:Not to be confused with
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318:immortalised cell lines
266:electrical resistivity
125:specifies a substance
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196:analytical chemistry
190:Analytical chemistry
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202:. Examples include
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137:reaction mechanism
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48:Reagents, such as
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242:chemical analysis
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298:antibodies
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458:: 15–17.
389:Substrate
310:oligomers
278:practical
274:technical
234:standards
142:catalysts
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789:Reagents
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