299:, smooth muscle, and nonmuscle cells. However, beginning in the 1970s, researchers began to discover new myosin genes in simple eukaryotes encoding proteins that acted as monomers and were therefore entitled Class I myosins. These new myosins were collectively termed "unconventional myosins" and have been found in many tissues other than muscle. These new superfamily members have been grouped according to phylogenetic relationships derived from a comparison of the amino acid sequences of their head domains, with each class being assigned a
364:
4342:
4330:
4318:
4306:
980:
941:
867:
828:
273:
452:
609:
688:
353:
576:
22:
605:
furthermore shown to act like a dynamic tether, retaining vesicles and organelles in the actin-rich periphery of cells. A recent single molecule in vitro reconstitution study on assembling actin filaments suggests that Myosin V travels farther on newly assembling (ADP-Pi rich) F-actin, while processive runlengths are shorter on older (ADP-rich) F-actin.
516:. The force-producing head domains stick out from the side of the thick filament, ready to walk along the adjacent actin-based thin filaments in response to the proper chemical signals and may be in either auto-inhibited or active conformation. The balance/transition between active and inactive states is subject to extensive chemical regulation.
327:
arm will cause the cargo to traverse a greater distance even though the lever arm undergoes the same angular displacement – just as a person with longer legs can move farther with each individual step. The velocity of a myosin motor depends upon the rate at which it passes through a complete kinetic cycle of ATP binding to the release of ADP.
264:
pulls against the actin. The release of the ADP molecule leads to the so-called rigor state of myosin. The binding of a new ATP molecule will release myosin from actin. ATP hydrolysis within the myosin will cause it to bind to actin again to repeat the cycle. The combined effect of the myriad power strokes causes the muscle to contract.
263:
through a power stroke mechanism fuelled by the energy released from ATP hydrolysis. The power stroke occurs at the release of phosphate from the myosin molecule after the ATP hydrolysis while myosin is tightly bound to actin. The effect of this release is a conformational change in the molecule that
612:
A ribbon diagram of the Myosin V molecular motor pseudo-colored to illustrate major subdomains. In the interest of visual clarity, important loops (which are often labeled separately in the literature) are not singled out. This perspective highlights the nucleotide-binding site and the separation of
326:
group causes the "power stroke", in which the "lever arm" or "neck" region of the heavy chain is dragged forward. Since the power stroke always moves the lever arm by the same angle, the length of the lever arm determines the displacement of the cargo relative to the actin filament. A longer lever
310:
Analysis of the amino acid sequences of different myosins shows great variability among the tail domains, but strong conservation of head domain sequences. Presumably this is so the myosins may interact, via their tails, with a large number of different cargoes, while the goal in each case – to move
604:
and has a step size of 36 nm. It translocates (walks) along actin filaments traveling towards the barbed end (+ end) of the filaments. Myosin V is involved in the transport of cargo (e.g. RNA, vesicles, organelles, mitochondria) from the center of the cell to the periphery, but has been
455:
Self-inhibition of Myosin II. The movie begins with Myosin II in the 10S conformation with a folded tail domain, the blocked head and free head. The movie schematically depicts tail unfolding and the resulting active 6S confirmation followed by tail folding back to the 10S conformation. The
283:
The wide variety of myosin genes found throughout the eukaryotic phyla were named according to different schemes as they were discovered. The nomenclature can therefore be somewhat confusing when attempting to compare the functions of myosin proteins within and between organisms.
169:. Some isoforms have specialized functions in certain cell types (such as muscle), while other isoforms are ubiquitous. The structure and function of myosin is globally conserved across species, to the extent that rabbit muscle myosin II will bind to actin from an
695:
Myosin VI is an unconventional myosin motor, which is primarily processive as a dimer, but also acts as a nonprocessive monomer. It walks along actin filaments, travelling towards the pointed end (- end) of the filaments. Myosin VI is thought to transport
773:. Myosin X walks towards the barbed ends of filaments. Some research suggests it preferentially walks on bundles of actin, rather than single filaments. It is the first myosin motor found to exhibit this behavior.
756:
Myosin IX is a group of single-headed motor proteins. It was first shown to be minus-end directed, but a later study showed that it is plus-end directed. The movement mechanism for this myosin is poorly understood.
1014:
MYO18A A gene on chromosome 17q11.2 that encodes actin-based motor molecules with ATPase activity, which may be involved in maintaining stromal cell scaffolding required for maintaining intercellular contact.
674:
SH1 helix and Relay - These elements together provide an essential mechanism for coupling the enzymatic state of the motor domain to the powerstroke-producing region (converter domain, lever arm, and light
25:
Part of the myosin II structure. Atoms in the heavy chain are colored pink (on the left-hand side); atoms in the light chains are colored faded-orange and faded-yellow (also on the left-hand side).
512:
tails of the individual myosin molecules can auto-inhibit active function in the 10S conformation or upon phosphorylation, change to the 6S conformation and join, forming the thick filaments of the
1216:
Myosin light chains are distinct and have their own properties. They are not considered "myosins" but are components of the macromolecular complexes that make up the functional myosin enzymes.
744:
Myosin VIII is a plant-specific myosin linked to cell division; specifically, it is involved in regulating the flow of cytoplasm between cells and in the localization of vesicles to the
303:(see phylogenetic tree). The unconventional myosins also have divergent tail domains, suggesting unique functions. The now diverse array of myosins likely evolved from an ancestral
2151:
Matsuoka R, Yoshida MC, Furutani Y, Imamura S, Kanda N, Yanagisawa M, et al. (April 1993). "Human smooth muscle myosin heavy chain gene mapped to chromosomal region 16q12".
2186:
Pettersen EF, Goddard TD, Huang CC, Couch GS, Greenblatt DM, Meng EC, et al. (October 2004). "UCSF Chimera--a visualization system for exploratory research and analysis".
4103:"Seafood Paramyosins as Sources of Anti-Angiotensin-Converting-Enzyme and Anti-Dipeptidyl-Peptidase Peptides after Gastrointestinal Digestion: A Cheminformatic Investigation"
1677:
von der Ecken J, Heissler SM, Pathan-Chhatbar S, Manstein DJ, Raunser S (June 2016). "Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution".
769:. The dimerization of myosin X is thought to be antiparallel. This behavior has not been observed in other myosins. In mammalian cells, the motor is found to localize to
916:. Known functions include: transporting phagosomes to the nucleus and perturbing the developmentally regulated elimination of the macronucleus during conjugation.
712:
in the tail region. It has an extended lever arm consisting of five calmodulin binding IQ motifs followed by a single alpha helix (SAH) Myosin VII is required for
678:
Converter - This converts a change of conformation in the motor head to an angular displacement of the lever arm (in most cases reinforced with light chains).
322:
These differences in shape also determine the speed at which myosins can move along actin filaments. The hydrolysis of ATP and the subsequent release of the
344:
transport. It has a step size of 10 nm and has been implicated as being responsible for the adaptation response of the stereocilia in the inner ear.
6754:
218:
acts as a linker and as a lever arm for transducing force generated by the catalytic motor domain. The neck domain can also serve as a binding site for
211:
to generate force and to "walk" along the filament towards the barbed (+) end (with the exception of myosin VI, which moves towards the pointed (-) end).
4389:
http://cellimages.ascb.org/cdm4/item_viewer.php?CISOROOT=/p4041coll12&CISOPTR=101&CISOBOX=1&REC=2 Animation of a moving myosin motor protein
161:), there is no single "myosin"; rather it is a very large superfamily of genes whose protein products share the basic properties of actin binding, ATP
1323:. Paramyosin is responsible for the "catch" mechanism that enables sustained contraction of muscles with very little energy expenditure, such that a
4427:
4256:
Soldati T, Geissler H, Schwarz EC (1999). "How many is enough? Exploring the myosin repertoire in the model eukaryote
Dictyostelium discoideum".
2744:
2720:
3768:"A myosin XI tail domain homologous to the yeast myosin vacuole-binding domain interacts with plastids and stromules in Nicotiana benthamiana"
7588:
1973:
1291:
phyla. Invertebrate thick filaments are thought to be composed of an inner paramyosin core surrounded by myosin. The myosin interacts with
1804:
Goodson HV (1994). "Molecular evolution of the myosin superfamily: application of phylogenetic techniques to cell biological questions".
6236:
2659:"Direct evidence for functional smooth muscle myosin II in the 10S self-inhibited monomeric conformation in airway smooth muscle cells"
2551:"Direct evidence for functional smooth muscle myosin II in the 10S self-inhibited monomeric conformation in airway smooth muscle cells"
2280:"Direct evidence for functional smooth muscle myosin II in the 10S self-inhibited monomeric conformation in airway smooth muscle cells"
6256:
3033:
Kull FJ, Vale RD, Fletterick RJ (November 1998). "The case for a common ancestor: kinesin and myosin motor proteins and G proteins".
1403:
4384:
7447:
7012:
7002:
6956:
6188:
6173:
6168:
6163:
6158:
6148:
6069:
5778:
5758:
5728:
5723:
1330:
Paramyosins can be found in seafood. A recent computational study showed that following human intestinal digestion, paramyosins of
7646:
7031:
6747:
6398:
6393:
6388:
6383:
6138:
6128:
6118:
6113:
6084:
5788:
5783:
4830:
4718:
4708:
4683:
4663:
4567:
4547:
1269:
1210:
1194:
1172:
1166:
1150:
1136:
1064:
1048:
295:
and forms macromolecular filaments composed of multiple myosin subunits. Similar filament-forming myosin proteins were found in
6977:
4790:
3484:"Sink plasmodesmata as gateways for phloem unloading. Myosin VIII and calreticulin as molecular determinants of sink strength?"
1237:
3078:"Insertion or deletion of a single residue in the strut sequence of Dictyostelium myosin II abolishes strong binding to actin"
7715:
4174:
3415:
1583:
1565:
3956:"A dibasic motif in the tail of a class XIV apicomplexan myosin is an essential determinant of plasma membrane localization"
482:. Its exact function is unclear, but is believed to contribute to the structural stability of the myosin head along with MLC
8032:
5055:
6946:
3533:"Characterization of the unconventional myosin VIII in plant cells and its localization at the post-cytokinetic cell wall"
592:
and a tail that lacks any coiled-coil forming sequence. It has homology similar to the tail domains of Myosin VII and XV.
8063:
4420:
797:
interconnecting different plastids. Myosin XI also plays a key role in polar root tip growth and is necessary for proper
6740:
3572:
Inoue A, Saito J, Ikebe R, Ikebe M (April 2002). "Myosin IXb is a single-headed minus-end-directed processive motor".
456:
illustration is conceptual: transitory states and diffusive motions associated with folding/unfolding are not shown.
1363:
311:
along actin filaments – remains the same and therefore requires the same machinery in the motor. For example, the
7537:
5574:
8291:
7532:
5843:
5686:
4413:
7733:
7554:
6722:
6276:
2998:
Sweeney HL, Houdusse A (1 April 2010). "Structural and functional insights into the Myosin motor mechanism".
7602:
7124:
6919:
6847:
6843:
6820:
6780:
3615:
O'Connell CB, Mooseker MS (February 2003). "Native Myosin-IXb is a plus-, not a minus-end-directed motor".
2895:
Hammer JA, Sellers JR (December 2011). "Walking to work: roles for class V myosins as cargo transporters".
1295:, resulting in fibre contraction. Paramyosin is found in many different invertebrate species, for example,
7639:
7524:
4983:
410:
morphology, holding the two heavy chains together (imagine two snakes wrapped around each other, as in a
4292:
Molecular
Biology of the Cell. Alberts, Johnson, Lewis, Raff, Roberts, and Walter. 4th Edition. 949–952.
3907:"Toxoplasma gondii myosins B/C: one gene, two tails, two localizations, and a role in parasite division"
8068:
6454:
2848:"Myosin-Va restrains the trafficking of Na+/K+-ATPase-containing vesicles in alveolar epithelial cells"
2799:"Tilting and twirling as myosin V steps along actin filaments as detected by fluorescence polarization"
1536:"Acanthamoeba myosin. I. Isolation from Acanthamoeba castellanii of an enzyme similar to muscle myosin"
8296:
7583:
7022:
6793:
6767:
2716:
418:
domain is the region creating the angle between the head and tail. In smooth muscle, a single gene (
8301:
7699:
7138:
6833:
6798:
6771:
6687:
4392:
4378:
718:
1977:
1597:"Ras suppression potentiates rear actomyosin contractility-driven cell polarization and migration"
8286:
8261:
8135:
8130:
7508:
7471:
6810:
6732:
3809:"Two class XI myosins function in organelle trafficking and root hair development in Arabidopsis"
3905:
Delbac F, Sänger A, Neuhaus EM, Stratmann R, Ajioka JW, Toursel C, et al. (November 2001).
3433:"Analysis of the myosins encoded in the recently completed Arabidopsis thaliana genome sequence"
1578:
McMahon, T. A. 1984. Muscles, Reflexes and
Locomotion. 1st Edition. Princeton University Press.
165:(ATPase enzyme activity), and force transduction. Virtually all eukaryotic cells contain myosin
8219:
8048:
7688:
7678:
7632:
7238:
6878:
3531:
Reichelt S, Knight AE, Hodge TP, Baluska F, Samaj J, Volkmann D, et al. (September 1999).
1411:
1407:
728:
632:
398:
in length, which constitute the head and tail domains. Each of these heavy chains contains the
356:
287:
Skeletal muscle myosin, the most conspicuous of the myosin superfamily due to its abundance in
205:
122:
91:
382:
in most animal cell types. It is also found in non-muscle cells in contractile bundles called
7368:
7276:
5106:
4460:
4363:
4358:
3333:
990:
951:
877:
838:
668:
2657:
Milton DL, Schneck AN, Ziech DA, Ba M, Facemyer KC, Halayko AJ, et al. (January 2011).
2549:
Milton DL, Schneck AN, Ziech DA, Ba M, Facemyer KC, Halayko AJ, et al. (January 2011).
2278:
Milton DL, Schneck AN, Ziech DA, Ba M, Facemyer KC, Halayko AJ, et al. (January 2011).
7663:
5375:
4341:
4329:
4317:
4305:
3722:
3367:"Ca-Induced Rigidity Change of the Myosin VIIa IQ Motif-Single α Helix Lever Arm Extension"
2951:
2670:
2562:
2456:
2350:
2291:
2234:
1686:
1339:
561:
495:
425:
126:
3856:
Tominaga M, Kojima H, Yokota E, Orii H, Nakamori R, Katayama E, et al. (March 2003).
3011:
8:
7848:
7573:
6682:
5315:
4368:
4066:
Twarog BM (October 1976). "Aspects of smooth muscle function in molluscan catch muscle".
1999:
Batters C, Arthur CP, Lin A, Porter J, Geeves MA, Milligan RA, et al. (April 2004).
924:
Myosin XV is necessary for the development of the actin core structure of the non-motile
109:
that he held responsible for keeping the tension state in muscle. He called this protein
4205:
3726:
2955:
2674:
2566:
2460:
2354:
2295:
2238:
1941:
1916:
1690:
7154:
5135:
4765:
4281:
4129:
4102:
3954:
Hettmann C, Herm A, Geiter A, Frank B, Schwarz E, Soldati T, et al. (April 2000).
3931:
3906:
3833:
3808:
3743:
3710:
3686:
3659:
3640:
3597:
3508:
3483:
3342:
3317:
3293:
3268:
3249:
3195:
3170:
3143:
3118:
3058:
2972:
2939:
2920:
2872:
2847:
2846:
Lecuona E, Minin A, Trejo HE, Chen J, Comellas AP, Sun H, et al. (November 2009).
2823:
2798:
2693:
2658:
2634:
2609:
2585:
2550:
2526:
2501:
2477:
2444:
2420:
2395:
2371:
2338:
2314:
2279:
2255:
2222:
2074:
2049:
1954:
1710:
1508:
1483:
1459:
1434:
553:
520:
468:
432:
375:
260:
250:
219:
79:
4239:
4222:
4166:
3882:
3858:"Higher plant myosin XI moves processively on actin with 35 nm steps at high velocity"
3857:
2774:
2757:
2025:
2000:
1552:
8181:
8097:
8004:
7757:
6828:
6533:
4897:
4273:
4244:
4209:
4180:
4170:
4134:
4083:
4048:
4044:
4004:"MYO19 - Unconventional myosin-XIX - Homo sapiens (Human) - MYO19 gene & protein"
3985:
3980:
3955:
3936:
3887:
3838:
3789:
3748:
3691:
3632:
3589:
3554:
3549:
3532:
3513:
3464:
3459:
3449:
3432:
3411:
3388:
3347:
3298:
3241:
3200:
3171:"The path to visualization of walking myosin V by high-speed atomic force microscopy"
3148:
3099:
3050:
3015:
2977:
2912:
2877:
2828:
2779:
2698:
2639:
2590:
2531:
2482:
2425:
2376:
2319:
2260:
2203:
2168:
2133:
2079:
2030:
1946:
1897:
1892:
1867:
1848:
1813:
1786:
1745:
1741:
1702:
1659:
1624:
1616:
1596:
1579:
1557:
1513:
1464:
803:
766:
631:
Switch I - This contains a highly conserved SSR motif. Isomerizes in the presence of
601:
549:
341:
277:
4285:
3601:
3253:
3062:
2924:
1958:
1383:
624:-binding site - These elements together coordinate di-valent metal cations (usually
304:
7797:
7218:
7164:
7146:
6481:
5605:
4960:
4955:
4374:
4265:
4234:
4201:
4162:
4124:
4114:
4075:
4040:
3975:
3967:
3926:
3918:
3877:
3869:
3828:
3820:
3779:
3738:
3730:
3681:
3671:
3624:
3581:
3544:
3503:
3495:
3454:
3444:
3378:
3337:
3329:
3288:
3280:
3231:
3190:
3182:
3138:
3130:
3089:
3042:
3007:
2967:
2959:
2904:
2867:
2859:
2818:
2810:
2769:
2688:
2678:
2629:
2621:
2580:
2570:
2521:
2513:
2472:
2464:
2415:
2407:
2366:
2358:
2309:
2299:
2250:
2242:
2195:
2160:
2123:
2069:
2061:
2020:
2012:
1936:
1928:
1887:
1879:
1840:
1776:
1737:
1714:
1694:
1651:
1608:
1547:
1503:
1495:
1454:
1446:
536:
Myosin III is a poorly understood member of the myosin family. It has been studied
237:
35:
4079:
3709:
Ropars V, Yang Z, Isabet T, Blanc F, Zhou K, Lin T, et al. (September 2016).
3644:
2443:
Yang S, Tiwari P, Lee KH, Sato O, Ikebe M, Padrón R, et al. (December 2020).
2337:
Yang S, Tiwari P, Lee KH, Sato O, Ikebe M, Padrón R, et al. (December 2020).
2221:
Yang S, Tiwari P, Lee KH, Sato O, Ikebe M, Padrón R, et al. (December 2020).
2112:"Physiological pathways and molecular mechanisms regulating uterine contractility"
1535:
102:
8125:
8017:
7565:
7454:
7268:
6968:
6788:
6623:
5237:
5087:
4970:
1595:
Lin Y, Pal DS, Banerjee P, Banerjee T, Qin G, Deng Y, et al. (1 July 2024).
1388:
1351:
808:
723:
697:
617:
The Myosin V motor head can be subdivided into the following functional regions:
374:(also known as conventional myosin) is the myosin type responsible for producing
166:
106:
579:
Crystal structure of myosin V motor with essential light chain – nucleotide-free
340:
Myosin I, a ubiquitous cellular protein, functions as monomer and functions in
8082:
8058:
6888:
6586:
6449:
5146:
4977:
4486:
4405:
3664:
Proceedings of the
National Academy of Sciences of the United States of America
3284:
3236:
3219:
3134:
2663:
Proceedings of the
National Academy of Sciences of the United States of America
2555:
Proceedings of the
National Academy of Sciences of the United States of America
2284:
Proceedings of the
National Academy of Sciences of the United States of America
1612:
1343:
1335:
1331:
646:
639:
296:
118:
71:
4119:
3383:
3366:
3186:
3046:
2963:
2468:
2362:
2246:
1023:
Unconventional myosin XIX (Myo19) is a mitochondrial associated myosin motor.
447:. These bind the heavy chains in the "neck" region between the head and tail.
363:
240:. In some cases, the tail domain may play a role in regulating motor activity.
8280:
8147:
7655:
7432:
7042:
6650:
6645:
5610:
5480:
5429:
5379:
5319:
5241:
5209:
5150:
4936:
4455:
2016:
1620:
1359:
300:
288:
226:
75:
3676:
2683:
2575:
2304:
2164:
2128:
2111:
1844:
1676:
7826:
7779:
7417:
7390:
7319:
7312:
7295:
7290:
7264:
6494:
5549:
5304:
4848:
4440:
4277:
4248:
4184:
4138:
3989:
3940:
3891:
3873:
3842:
3793:
3752:
3695:
3636:
3593:
3558:
3517:
3468:
3392:
3351:
3302:
3245:
3204:
3152:
3103:
3094:
3077:
3054:
3019:
2981:
2916:
2881:
2832:
2783:
2702:
2643:
2594:
2535:
2486:
2429:
2380:
2323:
2264:
2207:
2137:
2083:
2034:
1950:
1901:
1852:
1706:
1663:
1628:
1517:
1468:
1347:
1300:
1288:
790:
786:
745:
713:
383:
312:
151:
134:
6466:
6444:
4213:
3971:
3922:
3824:
3365:
Li J, Chen Y, Deng Y, Unarta IC, Lu Q, Huang X, et al. (April 2017).
3218:
Ménétrey J, Llinas P, Mukherjea M, Sweeney HL, Houdusse A (October 2007).
2814:
2625:
2517:
2411:
2172:
1932:
1817:
1790:
1749:
1561:
1499:
657:
8176:
8151:
7970:
7941:
7742:
7513:
6640:
6591:
6461:
6351:
5681:
5125:
5080:
4999:
4921:
4469:
4087:
4052:
4003:
1883:
1781:
1764:
1296:
925:
902:
733:
709:
509:
407:
395:
379:
196:
187:
157:
146:
3784:
3767:
3734:
3499:
3269:"How are the cellular functions of myosin VI regulated within the cell?"
2608:
Yang S, Lee KH, Woodhead JL, Sato O, Ikebe M, Craig R (September 2019).
2500:
Yang S, Lee KH, Woodhead JL, Sato O, Ikebe M, Craig R (September 2019).
2394:
Yang S, Lee KH, Woodhead JL, Sato O, Ikebe M, Craig R (September 2019).
2050:"Non-muscle myosin II takes centre stage in cell adhesion and migration"
1698:
979:
940:
866:
827:
663:
U50 and L50 - The Upper (U50) and Lower (L50) domains are each around 50
236:
generally mediates interaction with cargo molecules and/or other myosin
132:
Following the discovery in 1973 of enzymes with myosin-like function in
8246:
8207:
8202:
8092:
8053:
8027:
8022:
7992:
7987:
7982:
7910:
7843:
7821:
7673:
7498:
7187:
6692:
6611:
6601:
6489:
5600:
5579:
5345:
5282:
5277:
5272:
5252:
5227:
5215:
5201:
5196:
5191:
5186:
5181:
5176:
5171:
5166:
5161:
5023:
4905:
4894:
4880:
4496:
4400:
4395:
4269:
2863:
1450:
928:
located in the inner ear. It is thought to be functional as a monomer.
906:
621:
544:
526:
444:
403:
399:
208:
162:
3119:"Mutations in the SH1 helix alter the thermal properties of myosin II"
2610:"The central role of the tail in switching off 10S myosin II activity"
2502:"The central role of the tail in switching off 10S myosin II activity"
2396:"The central role of the tail in switching off 10S myosin II activity"
2199:
2048:
Vicente-Manzanares M, Ma X, Adelstein RS, Horwitz AR (November 2009).
905:
phylum. The myosins localize to plasma membranes of the intracellular
8251:
8156:
8142:
8102:
8012:
7928:
7880:
7875:
7792:
7710:
7204:
6763:
6521:
6516:
6511:
6471:
6309:
6304:
6299:
5657:
5637:
5292:
5287:
5267:
5262:
5257:
5247:
5156:
5060:
4994:
3481:
1655:
1404:"myosin - definition of myosin in English from the Oxford dictionary"
1316:
798:
789:
in plant cells. It is responsible for the light-directed movement of
770:
765:
Myosin X is an unconventional myosin motor, which is functional as a
625:
600:
Myosin V is an unconventional myosin motor, which is processive as a
513:
451:
323:
292:
272:
87:
4161:. International Review of Cytology. Vol. 206. pp. 97–134.
4033:
Comparative
Biochemistry and Physiology. B, Comparative Biochemistry
2908:
2065:
2047:
291:, was the first to be discovered. This protein makes up part of the
8241:
8212:
8172:
7977:
6635:
6596:
6528:
6501:
6368:
6356:
6231:
6226:
5667:
5662:
5584:
5018:
5013:
4875:
3628:
3585:
1312:
1308:
1304:
794:
782:
613:
the U50 and L50 subdomains which form the actin-binding site cleft.
589:
411:
371:
256:
83:
6762:
4401:
3D macromolecular structures of myosin from the EM Data Bank(EMDB)
1728:
Cheney RE, Mooseker MS (February 1992). "Unconventional myosins".
8256:
7961:
7885:
7609:
7578:
7356:
7351:
7110:
7100:
7075:
7070:
6805:
6662:
6616:
6506:
6436:
6405:
6335:
6330:
6294:
6289:
6284:
6251:
6221:
6216:
6211:
6206:
5891:
5823:
5818:
5813:
5808:
5803:
5695:
5632:
5120:
5065:
5006:
4989:
4950:
4436:
3766:
Sattarzadeh A, Krahmer J, Germain AD, Hanson MR (November 2009).
1355:
1320:
1284:
667:. Their spatial separation forms a cleft critical for binding to
608:
569:
538:
7624:
3807:
Peremyslov VV, Prokhnevsky AI, Avisar D, Dolja VV (March 2008).
3806:
3482:
Baluska F, Cvrcková F, Kendrick-Jones J, Volkmann D (May 2001).
2001:"Myo1c is designed for the adaptation response in the inner ear"
1642:
Tyska MJ, Warshaw DM (January 2002). "The myosin power stroke".
687:
8197:
7486:
7128:
7095:
7065:
7060:
7055:
7050:
7007:
6997:
6992:
6987:
6982:
6951:
6939:
6934:
6929:
6924:
6912:
6907:
6902:
6851:
6581:
6563:
6558:
6553:
6548:
6538:
6373:
6266:
6261:
6246:
6241:
6153:
6099:
6064:
6039:
6034:
6029:
6024:
6014:
6009:
5999:
5984:
5979:
5861:
5856:
5851:
5763:
5753:
5733:
5718:
5713:
5708:
5703:
5569:
5340:
5335:
5092:
4758:
4753:
4743:
3765:
3711:"The myosin X motor is optimized for movement on actin bundles"
2741:
1281:
1204:
1200:
1188:
565:
267:
170:
114:
3217:
2150:
7956:
7946:
7868:
7863:
7858:
7853:
7542:
7481:
7464:
7459:
7307:
7285:
7251:
7246:
7231:
7209:
7197:
7192:
7182:
7177:
7172:
6897:
6873:
6606:
6378:
6361:
6198:
6193:
6183:
6178:
6143:
6133:
6123:
6108:
6089:
6079:
6074:
6059:
6054:
6049:
6044:
6019:
6004:
5994:
5989:
5974:
5969:
5949:
5944:
5939:
5934:
5929:
5924:
5919:
5914:
5909:
5904:
5899:
5871:
5866:
5833:
5828:
5798:
5793:
5773:
5768:
5748:
5738:
5653:
5531:
5526:
5521:
5516:
5511:
5506:
5501:
5496:
5491:
5486:
5470:
5465:
5460:
5455:
5450:
5445:
5440:
5435:
5410:
5405:
5400:
5395:
5390:
5385:
5365:
5360:
5355:
5350:
5330:
5325:
5035:
4965:
4914:
4911:
4908:
4900:
4889:
4886:
4883:
4868:
4863:
4858:
4853:
4825:
4815:
4800:
4733:
4723:
4703:
4678:
4673:
4658:
4648:
4643:
4638:
4633:
4628:
4623:
4608:
4562:
4557:
4552:
4542:
4537:
4532:
4511:
4506:
4501:
4491:
4478:
4227:
Biochimica et
Biophysica Acta (BBA) - Molecular Cell Research
3220:"The structural basis for the large powerstroke of myosin VI"
2762:
Biochimica et
Biophysica Acta (BBA) - Molecular Cell Research
1484:"The early history of the biochemistry of muscle contraction"
1292:
1265:
1257:
1245:
1182:
1176:
1162:
1146:
1142:
1132:
1126:
1122:
1118:
1114:
1110:
1106:
1094:
1060:
1056:
1052:
1044:
1040:
1036:
812:
557:
420:
316:
201:
95:
3904:
3660:"Antiparallel coiled-coil-mediated dimerization of myosin X"
2445:"Cryo-EM structure of the inhibited (10S) form of myosin II"
2339:"Cryo-EM structure of the inhibited (10S) form of myosin II"
2223:"Cryo-EM structure of the inhibited (10S) form of myosin II"
352:
7905:
7836:
7831:
7772:
7767:
7762:
7752:
7747:
7547:
7503:
7491:
7476:
7442:
7437:
7422:
7405:
7400:
7395:
7383:
7378:
7373:
7363:
7339:
7334:
7329:
7324:
7226:
6707:
6702:
6697:
6657:
6628:
6543:
6420:
6415:
6410:
6314:
5964:
5959:
5954:
5881:
5876:
5743:
5625:
5620:
5615:
5075:
5070:
5028:
4941:
4931:
4926:
4820:
4810:
4805:
4795:
4785:
4780:
4775:
4770:
4693:
4618:
4613:
4603:
4598:
4593:
4588:
4583:
4578:
1324:
1261:
1253:
1249:
1241:
1233:
1229:
1225:
1221:
1156:
1102:
1098:
1090:
1086:
1082:
1078:
1074:
1070:
575:
145:
Although myosin was originally thought to be restricted to
139:
113:. The term has been extended to include a group of similar
62:
47:
44:
4031:
Winkelman L (1976). "Comparative studies of paramyosins".
3530:
2940:"Actin age orchestrates myosin-5 and myosin-6 run lengths"
2185:
21:
7597:
7593:
4192:
Mooseker MS, Cheney RE (1995). "Unconventional myosins".
3315:
2938:
Zimmermann D, Santos A, Kovar DR, Rock RS (August 2015).
2937:
1831:
Hodge T, Cope MJ (October 2000). "A myosin family tree".
691:
State of myosin VI from PDB 2V26 before the power stroke
664:
142:
have been discovered throughout the realm of eukaryotes.
53:
3855:
3953:
909:
and may then be involved in the cell invasion process.
4255:
1998:
1594:
101:
The first myosin (M2) to be discovered was in 1864 by
4026:
4024:
3708:
3614:
3117:
Shibata K, Koyama T, Inde S, Iwai S, Chaen S (2017).
3116:
2845:
781:
Myosin XI directs the movement of organelles such as
638:
Switch II - This is the Kinase-GTPase version of the
56:
50:
3571:
3318:"Myosin VI: cellular functions and motor properties"
2656:
2548:
2277:
912:
This myosin is also found in the ciliated protozoan
3273:
Biochemical and Biophysical Research Communications
2607:
2499:
2393:
1762:
649:
GxxxxGK(S,T). This is the primary ATP binding site.
414:). Thus, myosin II has two heads. The intermediate
41:
38:
4021:
3658:Lu Q, Ye F, Wei Z, Wen Z, Zhang M (October 2012).
3266:
3032:
807:was discovered to be the fastest known processive
793:according to light intensity and the formation of
4101:Chai TT, Wong CC, Sabri MZ, Wong FC (June 2022).
4100:
3075:
2442:
2336:
2220:
1765:"Phylogenetic analysis of the myosin superfamily"
8278:
4435:
3364:
1914:
1865:
811:, moving at 7μm/s in 35 nm steps along the
708:Myosin VII is an unconventional myosin with two
435:(MLC), resulting in 2 per head, weighing 20 (MLC
229:complex and generally have regulatory functions.
225:which are distinct proteins that form part of a
4194:Annual Review of Cell and Developmental Biology
3322:Annual Review of Cell and Developmental Biology
2997:
2109:
1287:that has been described in a number of diverse
4191:
2105:
2103:
2101:
2099:
2097:
2095:
2093:
1915:Oliver TN, Berg JS, Cheney RE (October 1999).
1727:
1432:
428:of this gene result in four distinct isoforms.
7640:
6748:
4421:
3076:Sasaki N, Ohkura R, Sutoh K (December 2000).
2894:
1481:
1031:Note that not all of these genes are active.
424:)) codes for the heavy chains myosin II, but
105:. Kühne had extracted a viscous protein from
3358:
3316:Buss F, Spudich G, Kendrick-Jones J (2004).
3035:Journal of Muscle Research and Cell Motility
1866:Berg JS, Powell BC, Cheney RE (April 2001).
1641:
367:Cardiac sarcomere structure featuring myosin
268:Nomenclature, evolution, and the family tree
2090:
1533:
7647:
7633:
6755:
6741:
4428:
4414:
3657:
3168:
801:elongation. A specific Myosin XI found in
176:
4377:at the U.S. National Library of Medicine
4371:A video of a moving myosin motor protein.
4238:
4128:
4118:
4030:
3979:
3930:
3881:
3832:
3783:
3742:
3685:
3675:
3548:
3507:
3458:
3448:
3382:
3341:
3292:
3235:
3194:
3142:
3093:
2971:
2871:
2822:
2773:
2692:
2682:
2633:
2584:
2574:
2525:
2476:
2419:
2370:
2313:
2303:
2254:
2127:
2073:
2024:
1940:
1891:
1830:
1780:
1763:Cheney RE, Riley MA, Mooseker MS (1993).
1551:
1529:
1527:
1507:
1458:
1358:that inhibit the enzymatic activities of
660:that underpin the motor head's structure.
4157:Gavin RH (2001). "Myosins in protists".
3996:
3430:
3334:10.1146/annurev.cellbio.20.012103.094243
1327:can remain closed for extended periods.
901:This myosin group has been found in the
686:
642:DxxG. Isomerizes in the presence of ATP.
607:
574:
548:, where it is thought to play a role in
450:
362:
351:
271:
186:Most myosin molecules are composed of a
20:
4220:
3405:
3267:Buss F, Kendrick-Jones J (April 2008).
2796:
2790:
2755:
1971:
1806:Society of General Physiologists Series
1803:
8279:
4065:
2897:Nature Reviews. Molecular Cell Biology
2054:Nature Reviews. Molecular Cell Biology
1572:
1524:
1338:, Japanese abalone, Japanese scallop,
7628:
6736:
4409:
4156:
3164:
3162:
3012:10.1146/annurev.biophys.050708.133751
2993:
2991:
1433:Hartman MA, Spudich JA (April 2012).
138:, a global range of divergent myosin
8033:Connective tissue in skeletal muscle
4297:
2153:American Journal of Medical Genetics
1921:Cellular and Molecular Life Sciences
1568:from the original on 6 January 2016.
1435:"The myosin superfamily at a glance"
974:
935:
861:
822:
7732:
4206:10.1146/annurev.cb.11.110195.003221
3082:The Journal of Biological Chemistry
1540:The Journal of Biological Chemistry
13:
4149:
3159:
3110:
3069:
2988:
2188:Journal of Computational Chemistry
1769:Cell Motility and the Cytoskeleton
1644:Cell Motility and the Cytoskeleton
1475:
1426:
1026:
315:contains over 40 different myosin
14:
8313:
7654:
4352:
3169:Kodera N, Ando T (18 June 2014).
2803:The Journal of General Physiology
2614:The Journal of General Physiology
2506:The Journal of General Physiology
2400:The Journal of General Physiology
1917:"Tails of unconventional myosins"
1534:Pollard TD, Korn ED (July 1973).
1488:The Journal of General Physiology
1280:Paramyosin is a large, 93-115kDa
736:formation in mice and zebrafish.
560:, has been uncovered through the
330:
5056:Wiskott–Aldrich syndrome protein
4340:
4328:
4316:
4304:
4258:Cell Biochemistry and Biophysics
4223:"Myosins: a diverse superfamily"
3550:10.1046/j.1365-313X.1999.00553.x
3450:10.1186/gb-2001-2-7-research0024
3410:. Wiley-VCH. pp. 516, 518.
2758:"Myosins: a diverse superfamily"
2723:from the original on 7 July 2009
2110:Aguilar HN, Mitchell BF (2010).
978:
939:
865:
826:
34:
8064:Excitation–contraction coupling
6277:Microtubule organising proteins
4364:MBInfo – The Myosin Powerstroke
4094:
4059:
3947:
3898:
3849:
3800:
3759:
3702:
3651:
3608:
3565:
3524:
3475:
3424:
3399:
3309:
3260:
3211:
3026:
2931:
2888:
2839:
2749:
2735:
2709:
2650:
2601:
2542:
2493:
2436:
2387:
2330:
2271:
2214:
2179:
2144:
2041:
1992:
1965:
1908:
1859:
1824:
1797:
1756:
1730:Current Opinion in Cell Biology
1721:
1009:
244:
94:-dependent and responsible for
1670:
1635:
1588:
1482:Szent-Györgyi AG (June 2004).
1396:
1389:Merriam-Webster.com Dictionary
1376:
970:
857:
739:
671:and some regulatory compounds.
78:best known for their roles in
1:
6324:Microtubule severing proteins
4240:10.1016/S0167-4889(00)00005-7
4167:10.1016/S0074-7696(01)06020-X
4080:10.1152/physrev.1976.56.4.829
3960:Molecular Biology of the Cell
3123:Biophysics and Physicobiology
2775:10.1016/S0167-4889(00)00005-7
1872:Molecular Biology of the Cell
1553:10.1016/S0021-9258(19)43718-6
1369:
1360:angiotensin converting enzyme
1275:
1018:
931:
896:
818:
703:
531:
467:and actively participates in
82:and in a wide range of other
4984:actin depolymerizing factors
4045:10.1016/0305-0491(76)90310-2
2797:Warshaw DM (February 2012).
1868:"A millennial myosin census"
1742:10.1016/0955-0674(92)90055-H
919:
776:
751:
682:
583:
347:
259:molecules generate force in
7:
7525:Protein-synthesizing GTPase
6462:Plakoglobin (gamma catenin)
3911:The Journal of Cell Biology
3000:Annual Review of Biophysics
760:
645:P-loop - This contains the
628:) and catalyze hydrolysis:
595:
335:
10:
8320:
8069:Sliding filament mechanism
3285:10.1016/j.bbrc.2007.11.150
3237:10.1016/j.cell.2007.08.027
3135:10.2142/biophysico.14.0_67
1613:10.1038/s41556-024-01453-4
524:
518:
508:In muscle cells, the long
248:
181:
8232:
8190:
8165:
8118:
8111:
8081:
8041:
8003:
7927:
7894:
7817:
7810:
7788:
7723:
7709:
7698:
7687:
7662:
7584:Guanylate-binding protein
7563:
7522:
7262:
7136:
7123:
7088:
7040:
7021:
6967:
6887:
6866:
6859:
6842:
6819:
6779:
6768:acid anhydride hydrolases
6718:
6675:
6574:
6480:
6435:
6344:
6323:
6275:
6098:
5890:
5842:
5694:
5680:
5646:
5593:
5562:
5542:
5421:
5303:
5134:
5116:
5105:
5048:
4841:
4520:
4477:
4468:
4454:
4447:
4221:Sellers JR (March 2000).
4120:10.3390/molecules27123864
3431:Reddy AS, Day IS (2001).
3384:10.1016/j.str.2017.02.002
3187:10.1007/s12551-014-0141-7
2964:10.1016/j.cub.2015.06.033
2756:Sellers JR (March 2000).
2469:10.1038/s41586-020-3007-0
2363:10.1038/s41586-020-3007-0
2247:10.1038/s41586-020-3007-0
2116:Human Reproduction Update
1972:Maciver S (4 June 2003).
190:, neck, and tail domain.
7139:Heterotrimeric G protein
6834:Phosphoadenylylsulfatase
6688:Prokaryotic cytoskeleton
4379:Medical Subject Headings
4359:MBInfo – Myosin Isoforms
4159:A Survey of Cell Biology
2017:10.1038/sj.emboj.7600169
719:Dictyostelium discoideum
700:vesicles into the cell.
564:and is expressed in the
135:Acanthamoeba castellanii
16:Family of motor proteins
8262:Fukutin-related protein
6811:Thiamine-triphosphatase
3677:10.1073/pnas.1208642109
3406:Schliwa M, ed. (2003).
3047:10.1023/a:1005489907021
2852:Journal of Cell Science
2684:10.1073/pnas.1011784108
2576:10.1073/pnas.1011784108
2305:10.1073/pnas.1011784108
2165:10.1002/ajmg.1320460110
1845:10.1242/jcs.113.19.3353
1833:Journal of Cell Science
1439:Journal of Cell Science
914:Tetrahymena thermaphila
656:Transducer - The seven
588:Myosin IV has a single
494:) exist as a result of
402:head domain, while the
390:Myosin II contains two
177:Structure and functions
8220:Sarcoplasmic reticulum
8049:Neuromuscular junction
7957:elastic filament/titin
7679:Vascular smooth muscle
3095:10.1074/jbc.M001966200
1408:OxfordDictionaries.com
987:This section is empty.
948:This section is empty.
874:This section is empty.
835:This section is empty.
692:
614:
580:
465:regulatory light chain
457:
368:
360:
359:of muscle contraction.
357:Sliding filament model
280:
200:binds the filamentous
123:striated muscle tissue
26:
8292:Cytoskeleton proteins
7952:thick filament/myosin
7566:Polymerization motors
7277:Rho family of GTPases
5308:(hard alpha-keratins)
5139:(soft alpha-keratins)
4068:Physiological Reviews
3972:10.1091/mbc.11.4.1385
3923:10.1083/jcb.200012116
3825:10.1104/pp.107.113654
3715:Nature Communications
2815:10.1085/jgp.201210769
2626:10.1085/jgp.201912431
2518:10.1085/jgp.201912431
2412:10.1085/jgp.201912431
2129:10.1093/humupd/dmq016
1933:10.1007/s000180050426
1500:10.1085/jgp.200409091
690:
611:
578:
556:gene for myosin III,
525:Further information:
519:Further information:
486:. Two variants of MLC
480:essential light chain
478:is also known as the
463:is also known as the
454:
366:
355:
275:
24:
6723:cytoskeletal defects
6683:Major sperm proteins
3874:10.1093/emboj/cdg130
2858:(Pt 21): 3915–3922.
1884:10.1091/mbc.12.4.780
1782:10.1002/cm.970240402
1364:dipeptidyl peptidase
1354:could release short
1340:Mediterranean mussel
562:Human Genome Project
496:alternative splicing
127:smooth muscle tissue
7947:thin filament/actin
7933:(a, i, and h bands;
7574:dynamin superfamily
5136:Epithelial keratins
4385:The Myosin Homepage
3735:10.1038/ncomms12456
3727:2016NatCo...712456R
3670:(43): 17388–17393.
3617:Nature Cell Biology
3574:Nature Cell Biology
3500:10.1104/pp.126.1.39
3443:(7): RESEARCH0024.
3175:Biophysical Reviews
3088:(49): 38705–38709.
2956:2015CBio...25.2057Z
2675:2011PNAS..108.1421M
2567:2011PNAS..108.1421M
2461:2020Natur.588..521Y
2355:2020Natur.588..521Y
2296:2011PNAS..108.1421M
2239:2020Natur.588..521Y
1699:10.1038/nature18295
1691:2016Natur.534..724E
1601:Nature Cell Biology
1445:(Pt 7): 1627–1632.
433:myosin light chains
431:It also contains 4
4270:10.1007/BF02738121
2864:10.1242/jcs.046953
1451:10.1242/jcs.094300
1392:. Merriam-Webster.
693:
615:
581:
521:Muscle contraction
469:muscle contraction
458:
394:, each about 2000
376:muscle contraction
369:
361:
281:
251:Muscle contraction
80:muscle contraction
27:
8274:
8273:
8270:
8269:
8228:
8227:
8182:Myosatellite cell
8098:Intercalated disc
8077:
8076:
8005:Connective tissue
7923:
7922:
7919:
7918:
7886:Synemin/desmuslin
7806:
7805:
7622:
7621:
7618:
7617:
7119:
7118:
7084:
7083:
6829:Adenylylsulfatase
6730:
6729:
6671:
6670:
6431:
6430:
5676:
5675:
5558:
5557:
5101:
5100:
5044:
5043:
4298:Additional images
4176:978-0-12-364610-1
3785:10.1093/mp/ssp094
3537:The Plant Journal
3417:978-3-527-30594-0
3377:(4): 579–591.e4.
2950:(15): 2057–2062.
2455:(7838): 521–525.
2349:(7838): 521–525.
2233:(7838): 521–525.
2200:10.1002/jcc.20084
2194:(13): 1605–1612.
1839:(19): 3353–3354.
1685:(7609): 724–728.
1584:978-0-691-02376-2
1546:(13): 4682–4690.
1414:on 24 August 2012
1007:
1006:
968:
967:
894:
893:
855:
854:
804:Nicotiana tabacum
550:phototransduction
278:phylogenetic tree
98:-based motility.
8309:
8297:Protein families
8116:
8115:
7899:
7815:
7814:
7798:Laminin, alpha 2
7730:
7729:
7721:
7720:
7707:
7706:
7696:
7695:
7649:
7642:
7635:
7626:
7625:
7134:
7133:
6864:
6863:
6857:
6856:
6757:
6750:
6743:
6734:
6733:
5692:
5691:
5132:
5131:
5114:
5113:
4475:
4474:
4466:
4465:
4452:
4451:
4430:
4423:
4416:
4407:
4406:
4344:
4332:
4320:
4308:
4289:
4252:
4242:
4217:
4188:
4143:
4142:
4132:
4122:
4098:
4092:
4091:
4063:
4057:
4056:
4028:
4019:
4018:
4016:
4014:
4000:
3994:
3993:
3983:
3966:(4): 1385–1400.
3951:
3945:
3944:
3934:
3902:
3896:
3895:
3885:
3868:(6): 1263–1272.
3862:The EMBO Journal
3853:
3847:
3846:
3836:
3819:(3): 1109–1116.
3813:Plant Physiology
3804:
3798:
3797:
3787:
3778:(6): 1351–1358.
3763:
3757:
3756:
3746:
3706:
3700:
3699:
3689:
3679:
3655:
3649:
3648:
3612:
3606:
3605:
3569:
3563:
3562:
3552:
3528:
3522:
3521:
3511:
3488:Plant Physiology
3479:
3473:
3472:
3462:
3452:
3428:
3422:
3421:
3408:Molecular Motors
3403:
3397:
3396:
3386:
3362:
3356:
3355:
3345:
3313:
3307:
3306:
3296:
3264:
3258:
3257:
3239:
3215:
3209:
3208:
3198:
3181:(3–4): 237–260.
3166:
3157:
3156:
3146:
3114:
3108:
3107:
3097:
3073:
3067:
3066:
3030:
3024:
3023:
2995:
2986:
2985:
2975:
2935:
2929:
2928:
2892:
2886:
2885:
2875:
2843:
2837:
2836:
2826:
2794:
2788:
2787:
2777:
2753:
2747:
2739:
2733:
2732:
2730:
2728:
2713:
2707:
2706:
2696:
2686:
2669:(4): 1421–1426.
2654:
2648:
2647:
2637:
2620:(9): 1081–1093.
2605:
2599:
2598:
2588:
2578:
2561:(4): 1421–1426.
2546:
2540:
2539:
2529:
2512:(9): 1081–1093.
2497:
2491:
2490:
2480:
2440:
2434:
2433:
2423:
2406:(9): 1081–1093.
2391:
2385:
2384:
2374:
2334:
2328:
2327:
2317:
2307:
2290:(4): 1421–1426.
2275:
2269:
2268:
2258:
2218:
2212:
2211:
2183:
2177:
2176:
2148:
2142:
2141:
2131:
2107:
2088:
2087:
2077:
2045:
2039:
2038:
2028:
2011:(7): 1433–1440.
2005:The EMBO Journal
1996:
1990:
1989:
1987:
1985:
1976:. Archived from
1969:
1963:
1962:
1944:
1927:(3–4): 243–257.
1912:
1906:
1905:
1895:
1863:
1857:
1856:
1828:
1822:
1821:
1801:
1795:
1794:
1784:
1760:
1754:
1753:
1725:
1719:
1718:
1674:
1668:
1667:
1656:10.1002/cm.10014
1639:
1633:
1632:
1607:(7): 1062–1076.
1592:
1586:
1576:
1570:
1569:
1555:
1531:
1522:
1521:
1511:
1479:
1473:
1472:
1462:
1430:
1424:
1423:
1421:
1419:
1410:. Archived from
1400:
1394:
1393:
1380:
1002:
999:
989:You can help by
982:
975:
963:
960:
950:You can help by
943:
936:
889:
886:
876:You can help by
869:
862:
850:
847:
837:You can help by
830:
823:
406:tails take on a
276:Myosin unrooted
69:
68:
65:
64:
59:
58:
55:
52:
49:
46:
43:
40:
8319:
8318:
8312:
8311:
8310:
8308:
8307:
8306:
8302:Skeletal muscle
8277:
8276:
8275:
8266:
8234:
8224:
8186:
8161:
8107:
8084:
8073:
8037:
7999:
7934:
7932:
7915:
7895:
7890:
7802:
7784:
7725:
7714:
7701:
7690:
7683:
7665:
7658:
7653:
7623:
7614:
7559:
7518:
7269:Ras superfamily
7258:
7242:
7222:
7168:
7158:
7150:
7115:
7080:
7036:
7017:
6963:
6920:Plasma membrane
6883:
6838:
6815:
6789:Pyrophosphatase
6775:
6761:
6731:
6726:
6714:
6667:
6570:
6476:
6427:
6340:
6319:
6271:
6094:
5886:
5838:
5684:
5672:
5642:
5589:
5554:
5538:
5422:Ungrouped alpha
5417:
5307:
5299:
5138:
5124:
5118:
5108:
5097:
5040:
4837:
4516:
4458:
4443:
4434:
4355:
4348:
4345:
4336:
4333:
4324:
4321:
4312:
4309:
4300:
4295:
4177:
4152:
4150:Further reading
4147:
4146:
4099:
4095:
4064:
4060:
4039:(3B): 391–397.
4029:
4022:
4012:
4010:
4008:www.uniprot.org
4002:
4001:
3997:
3952:
3948:
3903:
3899:
3854:
3850:
3805:
3801:
3772:Molecular Plant
3764:
3760:
3707:
3703:
3656:
3652:
3613:
3609:
3570:
3566:
3529:
3525:
3480:
3476:
3429:
3425:
3418:
3404:
3400:
3363:
3359:
3314:
3310:
3265:
3261:
3216:
3212:
3167:
3160:
3115:
3111:
3074:
3070:
3031:
3027:
2996:
2989:
2944:Current Biology
2936:
2932:
2909:10.1038/nrm3248
2893:
2889:
2844:
2840:
2795:
2791:
2754:
2750:
2740:
2736:
2726:
2724:
2715:
2714:
2710:
2655:
2651:
2606:
2602:
2547:
2543:
2498:
2494:
2441:
2437:
2392:
2388:
2335:
2331:
2276:
2272:
2219:
2215:
2184:
2180:
2149:
2145:
2108:
2091:
2066:10.1038/nrm2786
2060:(11): 778–790.
2046:
2042:
1997:
1993:
1983:
1981:
1970:
1966:
1913:
1909:
1864:
1860:
1829:
1825:
1802:
1798:
1761:
1757:
1726:
1722:
1675:
1671:
1640:
1636:
1593:
1589:
1577:
1573:
1532:
1525:
1480:
1476:
1431:
1427:
1417:
1415:
1402:
1401:
1397:
1382:
1381:
1377:
1372:
1352:Whiteleg shrimp
1278:
1029:
1027:Genes in humans
1021:
1012:
1003:
997:
994:
973:
964:
958:
955:
934:
922:
899:
890:
884:
881:
860:
851:
845:
842:
821:
809:molecular motor
779:
763:
754:
742:
724:spermatogenesis
706:
685:
598:
586:
542:in the eyes of
534:
529:
523:
501:
493:
489:
485:
477:
462:
442:
438:
426:splice variants
350:
338:
333:
307:(see picture).
270:
261:skeletal muscle
253:
247:
184:
179:
107:skeletal muscle
61:
37:
33:
17:
12:
11:
5:
8317:
8316:
8305:
8304:
8299:
8294:
8289:
8287:Motor proteins
8272:
8271:
8268:
8267:
8265:
8264:
8259:
8254:
8249:
8244:
8238:
8236:
8230:
8229:
8226:
8225:
8223:
8222:
8217:
8216:
8215:
8205:
8200:
8194:
8192:
8188:
8187:
8185:
8184:
8179:
8169:
8167:
8163:
8162:
8160:
8159:
8154:
8145:
8140:
8139:
8138:
8133:
8122:
8120:
8113:
8109:
8108:
8106:
8105:
8100:
8095:
8089:
8087:
8079:
8078:
8075:
8074:
8072:
8071:
8066:
8061:
8059:Muscle spindle
8056:
8051:
8045:
8043:
8039:
8038:
8036:
8035:
8030:
8025:
8020:
8015:
8009:
8007:
8001:
8000:
7998:
7997:
7996:
7995:
7990:
7985:
7974:
7973:
7967:
7966:
7965:
7964:
7959:
7954:
7949:
7938:
7936:
7935:z and m lines)
7925:
7924:
7921:
7920:
7917:
7916:
7914:
7913:
7908:
7902:
7900:
7892:
7891:
7889:
7888:
7883:
7878:
7873:
7872:
7871:
7866:
7861:
7856:
7851:
7841:
7840:
7839:
7834:
7824:
7818:
7812:
7808:
7807:
7804:
7803:
7801:
7800:
7795:
7789:
7786:
7785:
7783:
7782:
7777:
7776:
7775:
7770:
7765:
7760:
7755:
7750:
7739:
7737:
7727:
7718:
7704:
7693:
7685:
7684:
7682:
7681:
7676:
7670:
7668:
7660:
7659:
7652:
7651:
7644:
7637:
7629:
7620:
7619:
7616:
7615:
7613:
7612:
7607:
7606:
7605:
7600:
7591:
7586:
7581:
7570:
7568:
7561:
7560:
7558:
7557:
7552:
7551:
7550:
7545:
7540:
7529:
7527:
7520:
7519:
7517:
7516:
7511:
7506:
7501:
7496:
7495:
7494:
7489:
7484:
7479:
7469:
7468:
7467:
7462:
7452:
7451:
7450:
7445:
7440:
7428:
7427:
7426:
7425:
7420:
7410:
7409:
7408:
7403:
7398:
7388:
7387:
7386:
7381:
7376:
7366:
7361:
7360:
7359:
7354:
7344:
7343:
7342:
7337:
7332:
7327:
7317:
7316:
7315:
7310:
7300:
7299:
7298:
7293:
7288:
7273:
7271:
7260:
7259:
7257:
7256:
7255:
7254:
7249:
7240:
7236:
7235:
7234:
7229:
7220:
7216:
7215:
7214:
7213:
7212:
7202:
7201:
7200:
7195:
7185:
7180:
7175:
7166:
7162:
7161:
7160:
7156:
7148:
7143:
7141:
7131:
7121:
7120:
7117:
7116:
7114:
7113:
7108:
7103:
7098:
7092:
7090:
7086:
7085:
7082:
7081:
7079:
7078:
7073:
7068:
7063:
7058:
7053:
7047:
7045:
7038:
7037:
7035:
7034:
7028:
7026:
7019:
7018:
7016:
7015:
7010:
7005:
7000:
6995:
6990:
6985:
6980:
6974:
6972:
6965:
6964:
6962:
6961:
6960:
6959:
6954:
6944:
6943:
6942:
6937:
6932:
6927:
6917:
6916:
6915:
6910:
6905:
6894:
6892:
6885:
6884:
6882:
6881:
6876:
6870:
6868:
6867:Cu++ (3.6.3.4)
6861:
6854:
6840:
6839:
6837:
6836:
6831:
6825:
6823:
6817:
6816:
6814:
6813:
6808:
6803:
6802:
6801:
6796:
6785:
6783:
6777:
6776:
6760:
6759:
6752:
6745:
6737:
6728:
6727:
6719:
6716:
6715:
6713:
6712:
6711:
6710:
6705:
6700:
6695:
6685:
6679:
6677:
6673:
6672:
6669:
6668:
6666:
6665:
6660:
6655:
6654:
6653:
6648:
6638:
6633:
6632:
6631:
6621:
6620:
6619:
6614:
6609:
6604:
6599:
6594:
6589:
6587:Corneodesmosin
6578:
6576:
6572:
6571:
6569:
6568:
6567:
6566:
6561:
6556:
6551:
6546:
6541:
6536:
6526:
6525:
6524:
6519:
6514:
6504:
6499:
6498:
6497:
6486:
6484:
6478:
6477:
6475:
6474:
6469:
6464:
6459:
6458:
6457:
6447:
6441:
6439:
6433:
6432:
6429:
6428:
6426:
6425:
6424:
6423:
6418:
6413:
6403:
6402:
6401:
6396:
6391:
6386:
6381:
6371:
6366:
6365:
6364:
6354:
6348:
6346:
6342:
6341:
6339:
6338:
6333:
6327:
6325:
6321:
6320:
6318:
6317:
6312:
6307:
6302:
6297:
6292:
6287:
6281:
6279:
6273:
6272:
6270:
6269:
6264:
6259:
6254:
6249:
6244:
6239:
6234:
6229:
6224:
6219:
6214:
6209:
6202:
6201:
6196:
6191:
6186:
6181:
6176:
6171:
6166:
6161:
6156:
6151:
6146:
6141:
6136:
6131:
6126:
6121:
6116:
6111:
6104:
6102:
6096:
6095:
6093:
6092:
6087:
6082:
6077:
6072:
6067:
6062:
6057:
6052:
6047:
6042:
6037:
6032:
6027:
6022:
6017:
6012:
6007:
6002:
5997:
5992:
5987:
5982:
5977:
5972:
5967:
5962:
5957:
5952:
5947:
5942:
5937:
5932:
5927:
5922:
5917:
5912:
5907:
5902:
5896:
5894:
5888:
5887:
5885:
5884:
5879:
5874:
5869:
5864:
5859:
5854:
5848:
5846:
5840:
5839:
5837:
5836:
5831:
5826:
5821:
5816:
5811:
5806:
5801:
5796:
5791:
5786:
5781:
5776:
5771:
5766:
5761:
5756:
5751:
5746:
5741:
5736:
5731:
5726:
5721:
5716:
5711:
5706:
5700:
5698:
5689:
5678:
5677:
5674:
5673:
5671:
5670:
5665:
5660:
5654:Nuclear lamins
5650:
5648:
5644:
5643:
5641:
5640:
5635:
5630:
5629:
5628:
5623:
5618:
5608:
5603:
5597:
5595:
5591:
5590:
5588:
5587:
5582:
5577:
5572:
5566:
5564:
5560:
5559:
5556:
5555:
5553:
5552:
5546:
5544:
5540:
5539:
5537:
5536:
5535:
5534:
5529:
5524:
5519:
5514:
5509:
5504:
5499:
5494:
5489:
5476:
5475:
5474:
5473:
5468:
5463:
5458:
5453:
5448:
5443:
5438:
5425:
5423:
5419:
5418:
5416:
5415:
5414:
5413:
5408:
5403:
5398:
5393:
5388:
5371:
5370:
5369:
5368:
5363:
5358:
5353:
5348:
5343:
5338:
5333:
5328:
5311:
5309:
5301:
5300:
5298:
5297:
5296:
5295:
5290:
5285:
5280:
5275:
5270:
5265:
5260:
5255:
5250:
5233:
5232:
5231:
5230:
5220:
5219:
5218:
5206:
5205:
5204:
5199:
5194:
5189:
5184:
5179:
5174:
5169:
5164:
5159:
5142:
5140:
5129:
5111:
5103:
5102:
5099:
5098:
5096:
5095:
5090:
5085:
5084:
5083:
5078:
5073:
5063:
5058:
5052:
5050:
5046:
5045:
5042:
5041:
5039:
5038:
5033:
5032:
5031:
5026:
5016:
5011:
5010:
5009:
5004:
5003:
5002:
4997:
4980:
4978:Arp2/3 complex
4975:
4974:
4973:
4968:
4963:
4958:
4947:
4946:
4945:
4944:
4939:
4934:
4929:
4919:
4918:
4917:
4903:
4892:
4873:
4872:
4871:
4866:
4861:
4856:
4845:
4843:
4839:
4838:
4836:
4835:
4834:
4833:
4828:
4823:
4818:
4813:
4808:
4803:
4798:
4793:
4788:
4783:
4778:
4773:
4763:
4762:
4761:
4756:
4748:
4747:
4746:
4738:
4737:
4736:
4728:
4727:
4726:
4721:
4713:
4712:
4711:
4706:
4698:
4697:
4696:
4688:
4687:
4686:
4681:
4676:
4668:
4667:
4666:
4661:
4653:
4652:
4651:
4646:
4641:
4636:
4631:
4626:
4621:
4616:
4611:
4606:
4601:
4596:
4591:
4586:
4581:
4573:
4572:
4571:
4565:
4560:
4555:
4550:
4545:
4540:
4535:
4526:
4524:
4518:
4517:
4515:
4514:
4509:
4504:
4499:
4494:
4489:
4483:
4481:
4472:
4463:
4456:Microfilaments
4449:
4445:
4444:
4433:
4432:
4425:
4418:
4410:
4404:
4403:
4398:
4390:
4387:
4382:
4372:
4366:
4361:
4354:
4353:External links
4351:
4350:
4349:
4346:
4339:
4337:
4334:
4327:
4325:
4322:
4315:
4313:
4310:
4303:
4299:
4296:
4294:
4293:
4290:
4264:(3): 389–411.
4253:
4218:
4189:
4175:
4153:
4151:
4148:
4145:
4144:
4093:
4074:(4): 829–838.
4058:
4020:
3995:
3946:
3917:(4): 613–623.
3897:
3848:
3799:
3758:
3701:
3650:
3629:10.1038/ncb924
3623:(2): 171–172.
3607:
3586:10.1038/ncb774
3580:(4): 302–306.
3564:
3543:(5): 555–567.
3523:
3474:
3437:Genome Biology
3423:
3416:
3398:
3357:
3308:
3279:(1): 165–175.
3259:
3230:(2): 300–308.
3210:
3158:
3109:
3068:
3041:(8): 877–886.
3025:
3006:(1): 539–557.
2987:
2930:
2887:
2838:
2789:
2748:
2734:
2708:
2649:
2600:
2541:
2492:
2435:
2386:
2329:
2270:
2213:
2178:
2143:
2122:(6): 725–744.
2089:
2040:
1991:
1980:on 2 June 2007
1964:
1907:
1878:(4): 780–794.
1858:
1823:
1796:
1775:(4): 215–223.
1755:
1720:
1669:
1634:
1587:
1571:
1523:
1494:(6): 631–641.
1474:
1425:
1395:
1374:
1373:
1371:
1368:
1344:Pacific oyster
1336:Humboldt squid
1332:common octopus
1277:
1274:
1273:
1272:
1214:
1213:
1207:
1197:
1191:
1185:
1179:
1169:
1159:
1153:
1139:
1129:
1067:
1028:
1025:
1020:
1017:
1011:
1008:
1005:
1004:
985:
983:
972:
969:
966:
965:
946:
944:
933:
930:
921:
918:
898:
895:
892:
891:
872:
870:
859:
856:
853:
852:
833:
831:
820:
817:
778:
775:
762:
759:
753:
750:
741:
738:
705:
702:
684:
681:
680:
679:
676:
672:
661:
653:
652:
651:
650:
647:Walker A motif
643:
640:Walker B motif
636:
597:
594:
585:
582:
533:
530:
506:
505:
504:
503:
499:
491:
487:
483:
475:
472:
460:
440:
436:
429:
349:
346:
337:
334:
332:
331:Myosin classes
329:
297:cardiac muscle
269:
266:
249:Main article:
246:
243:
242:
241:
230:
227:macromolecular
212:
183:
180:
178:
175:
76:motor proteins
15:
9:
6:
4:
3:
2:
8315:
8314:
8303:
8300:
8298:
8295:
8293:
8290:
8288:
8285:
8284:
8282:
8263:
8260:
8258:
8255:
8253:
8250:
8248:
8245:
8243:
8240:
8239:
8237:
8231:
8221:
8218:
8214:
8211:
8210:
8209:
8206:
8204:
8201:
8199:
8196:
8195:
8193:
8189:
8183:
8180:
8178:
8174:
8171:
8170:
8168:
8164:
8158:
8155:
8153:
8149:
8148:Microfilament
8146:
8144:
8141:
8137:
8134:
8132:
8129:
8128:
8127:
8124:
8123:
8121:
8117:
8114:
8110:
8104:
8101:
8099:
8096:
8094:
8091:
8090:
8088:
8086:
8080:
8070:
8067:
8065:
8062:
8060:
8057:
8055:
8052:
8050:
8047:
8046:
8044:
8040:
8034:
8031:
8029:
8026:
8024:
8021:
8019:
8016:
8014:
8011:
8010:
8008:
8006:
8002:
7994:
7991:
7989:
7986:
7984:
7981:
7980:
7979:
7976:
7975:
7972:
7969:
7968:
7963:
7960:
7958:
7955:
7953:
7950:
7948:
7945:
7944:
7943:
7940:
7939:
7937:
7930:
7926:
7912:
7909:
7907:
7904:
7903:
7901:
7898:
7893:
7887:
7884:
7882:
7879:
7877:
7874:
7870:
7867:
7865:
7862:
7860:
7857:
7855:
7852:
7850:
7847:
7846:
7845:
7842:
7838:
7835:
7833:
7830:
7829:
7828:
7825:
7823:
7820:
7819:
7816:
7813:
7811:Intracellular
7809:
7799:
7796:
7794:
7791:
7790:
7787:
7781:
7778:
7774:
7771:
7769:
7766:
7764:
7761:
7759:
7756:
7754:
7751:
7749:
7746:
7745:
7744:
7741:
7740:
7738:
7735:
7731:
7728:
7726:extracellular
7722:
7719:
7717:
7712:
7708:
7705:
7703:
7697:
7694:
7692:
7686:
7680:
7677:
7675:
7672:
7671:
7669:
7667:
7661:
7657:
7656:Muscle tissue
7650:
7645:
7643:
7638:
7636:
7631:
7630:
7627:
7611:
7608:
7604:
7601:
7599:
7595:
7592:
7590:
7587:
7585:
7582:
7580:
7577:
7576:
7575:
7572:
7571:
7569:
7567:
7562:
7556:
7553:
7549:
7546:
7544:
7541:
7539:
7536:
7535:
7534:
7531:
7530:
7528:
7526:
7521:
7515:
7512:
7510:
7507:
7505:
7502:
7500:
7497:
7493:
7490:
7488:
7485:
7483:
7480:
7478:
7475:
7474:
7473:
7470:
7466:
7463:
7461:
7458:
7457:
7456:
7453:
7449:
7446:
7444:
7441:
7439:
7436:
7435:
7434:
7430:
7429:
7424:
7421:
7419:
7416:
7415:
7414:
7411:
7407:
7404:
7402:
7399:
7397:
7394:
7393:
7392:
7389:
7385:
7382:
7380:
7377:
7375:
7372:
7371:
7370:
7367:
7365:
7362:
7358:
7355:
7353:
7350:
7349:
7348:
7345:
7341:
7338:
7336:
7333:
7331:
7328:
7326:
7323:
7322:
7321:
7318:
7314:
7311:
7309:
7306:
7305:
7304:
7301:
7297:
7294:
7292:
7289:
7287:
7284:
7283:
7282:
7278:
7275:
7274:
7272:
7270:
7266:
7261:
7253:
7250:
7248:
7245:
7244:
7243:
7237:
7233:
7230:
7228:
7225:
7224:
7223:
7217:
7211:
7208:
7207:
7206:
7203:
7199:
7196:
7194:
7191:
7190:
7189:
7186:
7184:
7181:
7179:
7176:
7174:
7171:
7170:
7169:
7163:
7159:
7153:
7152:
7151:
7145:
7144:
7142:
7140:
7135:
7132:
7130:
7126:
7122:
7112:
7109:
7107:
7104:
7102:
7099:
7097:
7094:
7093:
7091:
7087:
7077:
7074:
7072:
7069:
7067:
7064:
7062:
7059:
7057:
7054:
7052:
7049:
7048:
7046:
7044:
7043:P-type ATPase
7039:
7033:
7030:
7029:
7027:
7024:
7020:
7014:
7011:
7009:
7006:
7004:
7001:
6999:
6996:
6994:
6991:
6989:
6986:
6984:
6981:
6979:
6976:
6975:
6973:
6970:
6966:
6958:
6955:
6953:
6950:
6949:
6948:
6945:
6941:
6938:
6936:
6933:
6931:
6928:
6926:
6923:
6922:
6921:
6918:
6914:
6911:
6909:
6906:
6904:
6901:
6900:
6899:
6896:
6895:
6893:
6890:
6886:
6880:
6877:
6875:
6872:
6871:
6869:
6865:
6862:
6858:
6855:
6853:
6849:
6845:
6841:
6835:
6832:
6830:
6827:
6826:
6824:
6822:
6818:
6812:
6809:
6807:
6804:
6800:
6797:
6795:
6792:
6791:
6790:
6787:
6786:
6784:
6782:
6778:
6773:
6769:
6765:
6758:
6753:
6751:
6746:
6744:
6739:
6738:
6735:
6725:
6724:
6717:
6709:
6706:
6704:
6701:
6699:
6696:
6694:
6691:
6690:
6689:
6686:
6684:
6681:
6680:
6678:
6674:
6664:
6661:
6659:
6656:
6652:
6649:
6647:
6644:
6643:
6642:
6639:
6637:
6634:
6630:
6627:
6626:
6625:
6622:
6618:
6615:
6613:
6610:
6608:
6605:
6603:
6600:
6598:
6595:
6593:
6590:
6588:
6585:
6584:
6583:
6580:
6579:
6577:
6573:
6565:
6562:
6560:
6557:
6555:
6552:
6550:
6547:
6545:
6542:
6540:
6537:
6535:
6532:
6531:
6530:
6527:
6523:
6520:
6518:
6515:
6513:
6510:
6509:
6508:
6505:
6503:
6500:
6496:
6493:
6492:
6491:
6488:
6487:
6485:
6483:
6479:
6473:
6470:
6468:
6467:Delta catenin
6465:
6463:
6460:
6456:
6453:
6452:
6451:
6448:
6446:
6445:Alpha catenin
6443:
6442:
6440:
6438:
6434:
6422:
6419:
6417:
6414:
6412:
6409:
6408:
6407:
6404:
6400:
6397:
6395:
6392:
6390:
6387:
6385:
6382:
6380:
6377:
6376:
6375:
6372:
6370:
6367:
6363:
6360:
6359:
6358:
6355:
6353:
6350:
6349:
6347:
6343:
6337:
6334:
6332:
6329:
6328:
6326:
6322:
6316:
6313:
6311:
6308:
6306:
6303:
6301:
6298:
6296:
6293:
6291:
6288:
6286:
6283:
6282:
6280:
6278:
6274:
6268:
6265:
6263:
6260:
6258:
6255:
6253:
6250:
6248:
6245:
6243:
6240:
6238:
6235:
6233:
6230:
6228:
6225:
6223:
6220:
6218:
6215:
6213:
6210:
6208:
6205:cytoplasmic:
6204:
6203:
6200:
6197:
6195:
6192:
6190:
6187:
6185:
6182:
6180:
6177:
6175:
6172:
6170:
6167:
6165:
6162:
6160:
6157:
6155:
6152:
6150:
6147:
6145:
6142:
6140:
6137:
6135:
6132:
6130:
6127:
6125:
6122:
6120:
6117:
6115:
6112:
6110:
6106:
6105:
6103:
6101:
6097:
6091:
6088:
6086:
6083:
6081:
6078:
6076:
6073:
6071:
6068:
6066:
6063:
6061:
6058:
6056:
6053:
6051:
6048:
6046:
6043:
6041:
6038:
6036:
6033:
6031:
6028:
6026:
6023:
6021:
6018:
6016:
6013:
6011:
6008:
6006:
6003:
6001:
5998:
5996:
5993:
5991:
5988:
5986:
5983:
5981:
5978:
5976:
5973:
5971:
5968:
5966:
5963:
5961:
5958:
5956:
5953:
5951:
5948:
5946:
5943:
5941:
5938:
5936:
5933:
5931:
5928:
5926:
5923:
5921:
5918:
5916:
5913:
5911:
5908:
5906:
5903:
5901:
5898:
5897:
5895:
5893:
5889:
5883:
5880:
5878:
5875:
5873:
5870:
5868:
5865:
5863:
5860:
5858:
5855:
5853:
5850:
5849:
5847:
5845:
5841:
5835:
5832:
5830:
5827:
5825:
5822:
5820:
5817:
5815:
5812:
5810:
5807:
5805:
5802:
5800:
5797:
5795:
5792:
5790:
5787:
5785:
5782:
5780:
5777:
5775:
5772:
5770:
5767:
5765:
5762:
5760:
5757:
5755:
5752:
5750:
5747:
5745:
5742:
5740:
5737:
5735:
5732:
5730:
5727:
5725:
5722:
5720:
5717:
5715:
5712:
5710:
5707:
5705:
5702:
5701:
5699:
5697:
5693:
5690:
5688:
5683:
5679:
5669:
5666:
5664:
5661:
5659:
5655:
5652:
5651:
5649:
5645:
5639:
5636:
5634:
5631:
5627:
5624:
5622:
5619:
5617:
5614:
5613:
5612:
5611:Neurofilament
5609:
5607:
5604:
5602:
5599:
5598:
5596:
5592:
5586:
5583:
5581:
5578:
5576:
5573:
5571:
5568:
5567:
5565:
5561:
5551:
5548:
5547:
5545:
5541:
5533:
5530:
5528:
5525:
5523:
5520:
5518:
5515:
5513:
5510:
5508:
5505:
5503:
5500:
5498:
5495:
5493:
5490:
5488:
5485:
5484:
5483:
5482:
5481:chromosome 12
5478:
5477:
5472:
5469:
5467:
5464:
5462:
5459:
5457:
5454:
5452:
5449:
5447:
5444:
5442:
5439:
5437:
5434:
5433:
5432:
5431:
5430:chromosome 17
5427:
5426:
5424:
5420:
5412:
5409:
5407:
5404:
5402:
5399:
5397:
5394:
5392:
5389:
5387:
5384:
5383:
5382:
5381:
5380:chromosome 12
5377:
5373:
5372:
5367:
5364:
5362:
5359:
5357:
5354:
5352:
5349:
5347:
5344:
5342:
5339:
5337:
5334:
5332:
5329:
5327:
5324:
5323:
5322:
5321:
5320:chromosome 17
5317:
5313:
5312:
5310:
5306:
5305:Hair keratins
5302:
5294:
5291:
5289:
5286:
5284:
5281:
5279:
5276:
5274:
5271:
5269:
5266:
5264:
5261:
5259:
5256:
5254:
5251:
5249:
5246:
5245:
5244:
5243:
5242:chromosome 12
5239:
5235:
5234:
5229:
5226:
5225:
5224:
5221:
5217:
5214:
5213:
5212:
5211:
5210:chromosome 12
5207:
5203:
5200:
5198:
5195:
5193:
5190:
5188:
5185:
5183:
5180:
5178:
5175:
5173:
5170:
5168:
5165:
5163:
5160:
5158:
5155:
5154:
5153:
5152:
5151:chromosome 17
5148:
5144:
5143:
5141:
5137:
5133:
5130:
5127:
5122:
5115:
5112:
5110:
5107:Intermediate
5104:
5094:
5091:
5089:
5086:
5082:
5079:
5077:
5074:
5072:
5069:
5068:
5067:
5064:
5062:
5059:
5057:
5054:
5053:
5051:
5047:
5037:
5034:
5030:
5027:
5025:
5022:
5021:
5020:
5017:
5015:
5012:
5008:
5005:
5001:
4998:
4996:
4993:
4992:
4991:
4988:
4987:
4986:
4985:
4981:
4979:
4976:
4972:
4969:
4967:
4964:
4962:
4959:
4957:
4954:
4953:
4952:
4949:
4948:
4943:
4940:
4938:
4935:
4933:
4930:
4928:
4925:
4924:
4923:
4920:
4916:
4913:
4910:
4907:
4904:
4902:
4899:
4896:
4893:
4891:
4888:
4885:
4882:
4879:
4878:
4877:
4874:
4870:
4867:
4865:
4862:
4860:
4857:
4855:
4852:
4851:
4850:
4847:
4846:
4844:
4840:
4832:
4829:
4827:
4824:
4822:
4819:
4817:
4814:
4812:
4809:
4807:
4804:
4802:
4799:
4797:
4794:
4792:
4789:
4787:
4784:
4782:
4779:
4777:
4774:
4772:
4769:
4768:
4767:
4764:
4760:
4757:
4755:
4752:
4751:
4749:
4745:
4742:
4741:
4739:
4735:
4732:
4731:
4729:
4725:
4722:
4720:
4717:
4716:
4714:
4710:
4707:
4705:
4702:
4701:
4699:
4695:
4692:
4691:
4689:
4685:
4682:
4680:
4677:
4675:
4672:
4671:
4669:
4665:
4662:
4660:
4657:
4656:
4654:
4650:
4647:
4645:
4642:
4640:
4637:
4635:
4632:
4630:
4627:
4625:
4622:
4620:
4617:
4615:
4612:
4610:
4607:
4605:
4602:
4600:
4597:
4595:
4592:
4590:
4587:
4585:
4582:
4580:
4577:
4576:
4574:
4569:
4566:
4564:
4561:
4559:
4556:
4554:
4551:
4549:
4546:
4544:
4541:
4539:
4536:
4534:
4531:
4530:
4528:
4527:
4525:
4523:
4519:
4513:
4510:
4508:
4505:
4503:
4500:
4498:
4495:
4493:
4490:
4488:
4485:
4484:
4482:
4480:
4476:
4473:
4471:
4467:
4464:
4462:
4457:
4453:
4450:
4446:
4442:
4438:
4431:
4426:
4424:
4419:
4417:
4412:
4411:
4408:
4402:
4399:
4397:
4394:
4391:
4388:
4386:
4383:
4380:
4376:
4373:
4370:
4367:
4365:
4362:
4360:
4357:
4356:
4343:
4338:
4331:
4326:
4319:
4314:
4307:
4302:
4301:
4291:
4287:
4283:
4279:
4275:
4271:
4267:
4263:
4259:
4254:
4250:
4246:
4241:
4236:
4232:
4228:
4224:
4219:
4215:
4211:
4207:
4203:
4199:
4195:
4190:
4186:
4182:
4178:
4172:
4168:
4164:
4160:
4155:
4154:
4140:
4136:
4131:
4126:
4121:
4116:
4112:
4108:
4104:
4097:
4089:
4085:
4081:
4077:
4073:
4069:
4062:
4054:
4050:
4046:
4042:
4038:
4034:
4027:
4025:
4009:
4005:
3999:
3991:
3987:
3982:
3977:
3973:
3969:
3965:
3961:
3957:
3950:
3942:
3938:
3933:
3928:
3924:
3920:
3916:
3912:
3908:
3901:
3893:
3889:
3884:
3879:
3875:
3871:
3867:
3863:
3859:
3852:
3844:
3840:
3835:
3830:
3826:
3822:
3818:
3814:
3810:
3803:
3795:
3791:
3786:
3781:
3777:
3773:
3769:
3762:
3754:
3750:
3745:
3740:
3736:
3732:
3728:
3724:
3720:
3716:
3712:
3705:
3697:
3693:
3688:
3683:
3678:
3673:
3669:
3665:
3661:
3654:
3646:
3642:
3638:
3634:
3630:
3626:
3622:
3618:
3611:
3603:
3599:
3595:
3591:
3587:
3583:
3579:
3575:
3568:
3560:
3556:
3551:
3546:
3542:
3538:
3534:
3527:
3519:
3515:
3510:
3505:
3501:
3497:
3493:
3489:
3485:
3478:
3470:
3466:
3461:
3456:
3451:
3446:
3442:
3438:
3434:
3427:
3419:
3413:
3409:
3402:
3394:
3390:
3385:
3380:
3376:
3372:
3368:
3361:
3353:
3349:
3344:
3339:
3335:
3331:
3327:
3323:
3319:
3312:
3304:
3300:
3295:
3290:
3286:
3282:
3278:
3274:
3270:
3263:
3255:
3251:
3247:
3243:
3238:
3233:
3229:
3225:
3221:
3214:
3206:
3202:
3197:
3192:
3188:
3184:
3180:
3176:
3172:
3165:
3163:
3154:
3150:
3145:
3140:
3136:
3132:
3128:
3124:
3120:
3113:
3105:
3101:
3096:
3091:
3087:
3083:
3079:
3072:
3064:
3060:
3056:
3052:
3048:
3044:
3040:
3036:
3029:
3021:
3017:
3013:
3009:
3005:
3001:
2994:
2992:
2983:
2979:
2974:
2969:
2965:
2961:
2957:
2953:
2949:
2945:
2941:
2934:
2926:
2922:
2918:
2914:
2910:
2906:
2902:
2898:
2891:
2883:
2879:
2874:
2869:
2865:
2861:
2857:
2853:
2849:
2842:
2834:
2830:
2825:
2820:
2816:
2812:
2809:(2): 97–100.
2808:
2804:
2800:
2793:
2785:
2781:
2776:
2771:
2767:
2763:
2759:
2752:
2746:
2743:
2738:
2722:
2718:
2712:
2704:
2700:
2695:
2690:
2685:
2680:
2676:
2672:
2668:
2664:
2660:
2653:
2645:
2641:
2636:
2631:
2627:
2623:
2619:
2615:
2611:
2604:
2596:
2592:
2587:
2582:
2577:
2572:
2568:
2564:
2560:
2556:
2552:
2545:
2537:
2533:
2528:
2523:
2519:
2515:
2511:
2507:
2503:
2496:
2488:
2484:
2479:
2474:
2470:
2466:
2462:
2458:
2454:
2450:
2446:
2439:
2431:
2427:
2422:
2417:
2413:
2409:
2405:
2401:
2397:
2390:
2382:
2378:
2373:
2368:
2364:
2360:
2356:
2352:
2348:
2344:
2340:
2333:
2325:
2321:
2316:
2311:
2306:
2301:
2297:
2293:
2289:
2285:
2281:
2274:
2266:
2262:
2257:
2252:
2248:
2244:
2240:
2236:
2232:
2228:
2224:
2217:
2209:
2205:
2201:
2197:
2193:
2189:
2182:
2174:
2170:
2166:
2162:
2158:
2154:
2147:
2139:
2135:
2130:
2125:
2121:
2117:
2113:
2106:
2104:
2102:
2100:
2098:
2096:
2094:
2085:
2081:
2076:
2071:
2067:
2063:
2059:
2055:
2051:
2044:
2036:
2032:
2027:
2022:
2018:
2014:
2010:
2006:
2002:
1995:
1979:
1975:
1968:
1960:
1956:
1952:
1948:
1943:
1938:
1934:
1930:
1926:
1922:
1918:
1911:
1903:
1899:
1894:
1889:
1885:
1881:
1877:
1873:
1869:
1862:
1854:
1850:
1846:
1842:
1838:
1834:
1827:
1819:
1815:
1811:
1807:
1800:
1792:
1788:
1783:
1778:
1774:
1770:
1766:
1759:
1751:
1747:
1743:
1739:
1735:
1731:
1724:
1716:
1712:
1708:
1704:
1700:
1696:
1692:
1688:
1684:
1680:
1673:
1665:
1661:
1657:
1653:
1649:
1645:
1638:
1630:
1626:
1622:
1618:
1614:
1610:
1606:
1602:
1598:
1591:
1585:
1581:
1575:
1567:
1563:
1559:
1554:
1549:
1545:
1541:
1537:
1530:
1528:
1519:
1515:
1510:
1505:
1501:
1497:
1493:
1489:
1485:
1478:
1470:
1466:
1461:
1456:
1452:
1448:
1444:
1440:
1436:
1429:
1413:
1409:
1405:
1399:
1391:
1390:
1385:
1379:
1375:
1367:
1365:
1361:
1357:
1353:
1349:
1345:
1341:
1337:
1333:
1328:
1326:
1322:
1318:
1314:
1310:
1306:
1302:
1298:
1294:
1290:
1286:
1283:
1271:
1267:
1263:
1259:
1255:
1251:
1247:
1243:
1239:
1235:
1231:
1227:
1223:
1220:Light chain:
1219:
1218:
1217:
1212:
1208:
1206:
1202:
1199:Class XVIII:
1198:
1196:
1192:
1190:
1186:
1184:
1180:
1178:
1174:
1170:
1168:
1164:
1160:
1158:
1154:
1152:
1148:
1144:
1140:
1138:
1134:
1130:
1128:
1124:
1120:
1116:
1112:
1108:
1104:
1100:
1096:
1092:
1088:
1084:
1080:
1076:
1072:
1068:
1066:
1062:
1058:
1054:
1050:
1046:
1042:
1038:
1034:
1033:
1032:
1024:
1016:
1001:
992:
988:
984:
981:
977:
976:
962:
953:
949:
945:
942:
938:
937:
929:
927:
917:
915:
910:
908:
904:
888:
879:
875:
871:
868:
864:
863:
849:
840:
836:
832:
829:
825:
824:
816:
814:
810:
806:
805:
800:
796:
792:
788:
784:
774:
772:
768:
758:
749:
747:
737:
735:
731:
730:
725:
721:
720:
715:
711:
701:
699:
689:
677:
673:
670:
666:
662:
659:
655:
654:
648:
644:
641:
637:
634:
630:
629:
627:
623:
620:
619:
618:
610:
606:
603:
593:
591:
577:
573:
571:
567:
563:
559:
555:
551:
547:
546:
541:
540:
528:
522:
517:
515:
511:
497:
481:
473:
470:
466:
453:
449:
448:
446:
439:) and 17 (MLC
434:
430:
427:
423:
422:
417:
413:
409:
405:
401:
397:
393:
389:
388:
387:
385:
384:stress fibers
381:
377:
373:
365:
358:
354:
345:
343:
328:
325:
320:
318:
314:
308:
306:
302:
301:Roman numeral
298:
294:
290:
289:muscle fibers
285:
279:
274:
265:
262:
258:
252:
239:
235:
231:
228:
224:
223:
217:
213:
210:
207:
203:
199:
198:
193:
192:
191:
189:
174:
172:
168:
164:
160:
159:
154:
153:
148:
143:
141:
137:
136:
130:
128:
124:
120:
117:found in the
116:
112:
108:
104:
103:Wilhelm Kühne
99:
97:
93:
89:
86:processes in
85:
81:
77:
73:
67:
31:
23:
19:
8126:Muscle fiber
7951:
7896:
7827:Dystrobrevin
7780:Dystroglycan
7412:
7346:
7302:
7280:
7265:Small GTPase
7105:
6879:Wilson/ATP7B
6874:Menkes/ATP7A
6720:
6495:Dystroglycan
6450:Beta catenin
5682:Microtubules
5550:Beta-keratin
5479:
5428:
5374:
5314:
5236:
5222:
5208:
5145:
4982:
4849:Tropomodulin
4521:
4441:cytoskeleton
4369:Myosin Video
4261:
4257:
4230:
4226:
4197:
4193:
4158:
4113:(12): 3864.
4110:
4106:
4096:
4071:
4067:
4061:
4036:
4032:
4011:. Retrieved
4007:
3998:
3963:
3959:
3949:
3914:
3910:
3900:
3865:
3861:
3851:
3816:
3812:
3802:
3775:
3771:
3761:
3718:
3714:
3704:
3667:
3663:
3653:
3620:
3616:
3610:
3577:
3573:
3567:
3540:
3536:
3526:
3494:(1): 39–46.
3491:
3487:
3477:
3440:
3436:
3426:
3407:
3401:
3374:
3370:
3360:
3325:
3321:
3311:
3276:
3272:
3262:
3227:
3223:
3213:
3178:
3174:
3126:
3122:
3112:
3085:
3081:
3071:
3038:
3034:
3028:
3003:
2999:
2947:
2943:
2933:
2903:(1): 13–26.
2900:
2896:
2890:
2855:
2851:
2841:
2806:
2802:
2792:
2765:
2761:
2751:
2737:
2725:. Retrieved
2717:"New Page 2"
2711:
2666:
2662:
2652:
2617:
2613:
2603:
2558:
2554:
2544:
2509:
2505:
2495:
2452:
2448:
2438:
2403:
2399:
2389:
2346:
2342:
2332:
2287:
2283:
2273:
2230:
2226:
2216:
2191:
2187:
2181:
2159:(1): 61–67.
2156:
2152:
2146:
2119:
2115:
2057:
2053:
2043:
2008:
2004:
1994:
1982:. Retrieved
1978:the original
1967:
1924:
1920:
1910:
1875:
1871:
1861:
1836:
1832:
1826:
1809:
1805:
1799:
1772:
1768:
1758:
1736:(1): 27–35.
1733:
1729:
1723:
1682:
1678:
1672:
1647:
1643:
1637:
1604:
1600:
1590:
1574:
1543:
1539:
1491:
1487:
1477:
1442:
1438:
1428:
1416:. Retrieved
1412:the original
1398:
1387:
1378:
1348:sea cucumber
1329:
1301:Sipunculidea
1289:invertebrate
1279:
1215:
1030:
1022:
1013:
1010:Myosin XVIII
995:
991:adding to it
986:
956:
952:adding to it
947:
923:
913:
911:
900:
882:
878:adding to it
873:
843:
839:adding to it
834:
802:
791:chloroplasts
787:mitochondria
780:
764:
755:
746:phragmoplast
743:
727:
717:
714:phagocytosis
710:FERM domains
707:
694:
616:
599:
587:
543:
537:
535:
507:
479:
464:
419:
415:
392:heavy chains
391:
380:muscle cells
370:
339:
321:
313:human genome
309:
286:
282:
254:
245:Power stroke
233:
222:light chains
221:
215:
195:
185:
156:
150:
147:muscle cells
144:
133:
131:
110:
100:
29:
28:
18:
8177:Muscle cell
8152:Myofilament
7971:Tropomyosin
7942:Myofilament
7743:Sarcoglycan
7589:Mitofusin-1
7564:3.6.5.5-6:
7533:Prokaryotic
6641:Plakophilin
6592:Desmoplakin
6352:Tau protein
5126:Cytokeratin
4922:Tropomyosin
4470:Myofilament
4233:(1): 3–22.
4200:: 633–675.
3328:: 649–676.
2768:(1): 3–22.
2727:16 December
1812:: 141–157.
1650:(1): 1–15.
1297:Brachiopoda
1209:Class XIX:
1193:Class XVI:
1161:Class VII:
1131:Class III:
971:Myosin XVII
926:stereocilia
903:Apicomplexa
858:Myosin XIII
740:Myosin VIII
734:stereocilia
510:coiled-coil
408:coiled-coil
396:amino acids
234:tail domain
216:neck domain
204:, and uses
197:head domain
90:. They are
8281:Categories
8247:Telethonin
8208:Sarcolemma
8203:Sarcoplasm
8136:extrafusal
8131:intrafusal
8093:Myocardium
8054:Motor unit
8028:Endomysium
8023:Perimysium
7911:Caveolin 3
7844:Syntrophin
7822:Dystrophin
7674:Calmodulin
7555:Eukaryotic
7188:Transducin
7025:(3.6.3.10)
6764:Hydrolases
6721:See also:
6693:Crescentin
6612:Periplakin
6602:Envoplakin
6490:Dystrophin
6107:axonemal:
5601:Internexin
5580:Peripherin
2742:EntrezGene
1974:"Myosin I"
1418:20 January
1370:References
1276:Paramyosin
1187:Class XV:
1171:Class IX:
1155:Class VI:
1069:Class II:
1019:Myosin XIX
932:Myosin XVI
897:Myosin XIV
819:Myosin XII
815:filament.
729:C. elegans
704:Myosin VII
622:Nucleotide
552:. A human
545:Drosophila
532:Myosin III
527:Meromyosin
498:at the MLC
404:C-terminal
400:N-terminal
209:hydrolysis
163:hydrolysis
88:eukaryotes
8252:Dysferlin
8235:ungrouped
8157:Sarcomere
8143:Myofibril
8103:Nebulette
8013:Epimysium
7929:Sarcomere
7881:Dysbindin
7876:Syncoilin
7793:Sarcospan
7724:Membrane/
7711:Costamere
7523:3.6.5.3:
7263:3.6.5.2:
7205:Gustducin
7137:3.6.5.1:
6971:(3.6.3.9)
6891:(3.6.3.8)
6794:Inorganic
6310:Centrin 3
6305:Centrin 2
6300:Centrin 1
5638:Syncoilin
5543:Not alpha
5109:filaments
5061:Fibrillin
4107:Molecules
3721:: 12456.
3371:Structure
3129:: 67–73.
1621:1476-4679
1317:Arachnida
1181:Class X:
1141:Class V:
1035:Class I:
998:July 2024
959:July 2024
920:Myosin XV
907:parasites
885:July 2024
846:July 2024
799:root hair
795:stromules
777:Myosin XI
771:filopodia
752:Myosin IX
698:endocytic
683:Myosin VI
658:β-strands
626:magnesium
584:Myosin IV
554:homologue
514:sarcomere
372:Myosin II
348:Myosin II
324:phosphate
305:precursor
293:sarcomere
257:myosin II
255:Multiple
8242:Myotilin
8213:T-tubule
8173:Myoblast
8018:Fascicle
7978:Troponin
7897:related:
7700:Skeletal
7689:Striated
6799:Thiamine
6676:Nonhuman
6636:Vinculin
6597:Dystonin
6529:Spectrin
6502:Utrophin
6482:Membrane
6437:Catenins
6369:Stathmin
6357:Dynactin
6237:DYNC2LI1
6232:DYNC1LI2
6227:DYNC1LI1
5892:Kinesins
5696:Tubulins
5585:Vimentin
5117:Type 1/2
5019:Profilin
5014:Gelsolin
4876:Troponin
4437:Proteins
4323:Phase 2
4286:13319819
4278:10403058
4249:10722873
4185:11407764
4139:35744987
4013:21 April
3990:10749937
3941:11706051
3892:12628919
3843:18178669
3794:19995734
3753:27580874
3696:23012428
3637:12563277
3602:12158370
3594:11901422
3559:10504577
3518:11351069
3469:11516337
3393:28262393
3352:15473855
3303:18068125
3254:14102005
3246:17956731
3205:25505494
3153:28630813
3104:11005804
3063:25508217
3055:10047987
3020:20192767
2982:26190073
2925:11853457
2917:22146746
2882:19808891
2833:22291143
2784:10722873
2721:Archived
2703:21205888
2644:31387899
2595:21205888
2536:31387899
2487:33268893
2430:31387899
2381:33268893
2324:21205888
2265:33268893
2208:15264254
2138:20551073
2084:19851336
2035:15014434
1959:23407921
1951:11212352
1942:11147021
1902:11294886
1853:10984423
1707:27324845
1664:11810692
1629:38951708
1566:Archived
1518:15173217
1469:22566666
1384:"Myosin"
1356:peptides
1313:Mollusca
1309:Annelida
1305:Nematoda
783:plastids
761:Myosin X
675:chains).
596:Myosin V
590:IQ motif
412:caduceus
336:Myosin I
238:subunits
167:isoforms
121:of both
84:motility
70:) are a
8257:Fukutin
8083:Cardiac
8042:General
7962:nebulin
7610:Tubulin
7579:Dynamin
7431:other:
7111:Katanin
7101:Kinesin
7076:ATP13A3
7071:ATP13A2
6806:Apyrase
6663:PLEKHA7
6617:Plectin
6582:Plakins
6507:Ankyrin
6406:Dynamin
6336:Spastin
6331:Katanin
6295:CAMSAP3
6290:CAMSAP2
6285:CAMSAP1
6257:DYNLRB2
6252:DYNLRB1
6222:DYNC1I2
6217:DYNC1I1
6212:DYNC2H1
6207:DYNC1H1
6100:Dyneins
5824:TUBGCP6
5819:TUBGCP5
5814:TUBGCP4
5809:TUBGCP3
5804:TUBGCP2
5633:Synemin
5376:type II
5238:type II
5121:Keratin
5066:Filamin
5007:Destrin
4990:Cofilin
4951:Actinin
4522:Myosins
4439:of the
4396:3.6.4.1
4375:Myosins
4347:Phase 4
4335:Phase 3
4311:Phase 1
4214:8689571
4130:9229108
3932:2198869
3834:2259062
3744:5025751
3723:Bibcode
3687:3491486
3509:1540107
3343:1693462
3294:2635068
3196:4256461
3144:5468464
2973:4556227
2952:Bibcode
2873:2773192
2824:3269787
2694:3029703
2671:Bibcode
2635:6719407
2586:3029703
2563:Bibcode
2527:6719407
2478:7746622
2457:Bibcode
2421:6719407
2372:7746622
2351:Bibcode
2315:3029703
2292:Bibcode
2256:7746622
2235:Bibcode
2173:7684189
2075:2834236
1818:7939893
1791:8477454
1750:1558751
1715:4472407
1687:Bibcode
1562:4268863
1509:2234565
1460:3346823
1321:Insecta
1285:protein
570:cochlea
539:in vivo
474:The MLC
459:The MLC
342:vesicle
220:myosin
182:Domains
149:(hence
115:ATPases
30:Myosins
8233:Other/
8198:Desmin
8085:muscle
7702:muscle
7691:muscle
7666:muscle
7664:Smooth
7487:ARL13B
7347:RhoBTB
7241:α12/13
7129:GTPase
7106:Myosin
7096:Dynein
7066:ATP12A
7061:ATP11B
7056:ATP10A
7051:ATP8B1
7041:Other
7013:ATP1B4
7008:ATP1B3
7003:ATP1B2
6998:ATP1B1
6993:ATP1A4
6988:ATP1A3
6983:ATP1A2
6978:ATP1A1
6969:Na+/K+
6957:ATP2C2
6952:ATP2C1
6940:ATP2B4
6935:ATP2B3
6930:ATP2B2
6925:ATP2B1
6913:ATP2A3
6908:ATP2A2
6903:ATP2A1
6852:ATPase
6564:SPTBN5
6559:SPTBN4
6554:SPTBN2
6549:SPTBN1
6539:SPTAN1
6374:Tektin
6267:DYNLT3
6262:DYNLT1
6247:DYNLL2
6242:DYNLL1
6189:DNALI1
6174:DNAH17
6169:DNAH14
6164:DNAH13
6159:DNAH12
6154:DNAH11
6149:DNAH10
6070:KIF26B
6065:KIF26A
6040:KIF21B
6035:KIF21A
6030:KIF20B
6025:KIF20A
6015:KIF18B
6010:KIF18A
6000:KIF16B
5985:KIF13B
5980:KIF13A
5779:TUBB4Q
5764:TUBB2C
5759:TUBB2B
5754:TUBB2A
5734:TUBA4A
5729:TUBA3E
5724:TUBA3D
5719:TUBA3C
5714:TUBA1C
5709:TUBA1B
5704:TUBA1A
5647:Type 5
5606:Nestin
5594:Type 4
5570:Desmin
5563:Type 3
5316:type I
5147:type I
5093:TRIOBP
4759:MYO18B
4754:MYO18A
4750:XVIII
4744:MYO15A
4479:Actins
4381:(MeSH)
4284:
4276:
4247:
4212:
4183:
4173:
4137:
4127:
4088:185635
4086:
4053:987889
4051:
3988:
3978:
3939:
3929:
3890:
3883:151065
3880:
3841:
3831:
3792:
3751:
3741:
3694:
3684:
3645:687308
3643:
3635:
3600:
3592:
3557:
3516:
3506:
3467:
3457:
3414:
3391:
3350:
3340:
3301:
3291:
3252:
3244:
3203:
3193:
3151:
3141:
3102:
3061:
3053:
3018:
2980:
2970:
2923:
2915:
2880:
2870:
2831:
2821:
2782:
2701:
2691:
2642:
2632:
2593:
2583:
2534:
2524:
2485:
2475:
2449:Nature
2428:
2418:
2379:
2369:
2343:Nature
2322:
2312:
2263:
2253:
2227:Nature
2206:
2171:
2136:
2082:
2072:
2033:
2026:391074
2023:
1984:23 May
1957:
1949:
1939:
1900:
1890:
1851:
1816:
1789:
1748:
1713:
1705:
1679:Nature
1662:
1627:
1619:
1582:
1560:
1516:
1506:
1467:
1457:
1350:, and
1319:, and
1282:muscle
1205:MYO18B
1201:MYO18A
1189:MYO15A
566:retina
171:amoeba
155:(s) +
111:myosin
72:family
8191:Other
8166:Cells
8119:Fiber
7543:EF-Tu
7482:SAR1B
7465:RAB27
7460:RAB23
7413:RhoDF
7303:RhoUV
7286:CDC42
7281:Cdc42
7267:>
7252:GNA13
7247:GNA12
7232:GNA11
7221:αq/11
7210:GNAT3
7198:GNAT2
7193:GNAT1
7183:GNAI3
7178:GNAI2
7173:GNAI1
7125:3.6.5
7089:3.6.4
7032:ATP4A
7023:H+/K+
6898:SERCA
6860:3.6.3
6844:3.6.3
6821:3.6.2
6781:3.6.1
6624:Talin
6607:MACF1
6575:Other
6534:SPTA1
6399:TEKT5
6394:TEKT4
6389:TEKT3
6384:TEKT2
6379:TEKT1
6362:DCTN1
6345:Other
6199:DNAL4
6194:DNAL1
6184:DNAI2
6179:DNAI1
6144:DNAH9
6139:DNAH8
6134:DNAH7
6129:DNAH6
6124:DNAH5
6119:DNAH3
6114:DNAH2
6109:DNAH1
6090:KIFC3
6085:KIFC2
6080:KIFC1
6075:KIF27
6060:KIF25
6055:KIF24
6050:KIF23
6045:KIF22
6020:KIF19
6005:KIF17
5995:KIF15
5990:KIF14
5975:KIF12
5970:KIF11
5950:KIF5C
5945:KIF5B
5940:KIF5A
5935:KIF4B
5930:KIF4A
5925:KIF3C
5920:KIF3B
5915:KIF2C
5910:KIF2A
5905:KIF1B
5900:KIF1A
5872:MAP1B
5867:MAP1A
5834:TUBE1
5829:TUBD1
5799:TUBG2
5794:TUBG1
5789:TUBB8
5784:TUBB6
5774:TUBB4
5769:TUBB3
5749:TUBB1
5739:TUBA8
5088:Espin
5049:Other
5036:Titin
4842:Other
4831:MYLL1
4826:MYLK2
4816:MYLIP
4801:MYL6B
4734:MYO10
4724:MYO9B
4719:MYO9A
4709:MYO7B
4704:MYO7A
4684:MYO5C
4679:MYO5B
4674:MYO5A
4664:MYO3B
4659:MYO3A
4649:MYH16
4644:MYH15
4639:MYH14
4634:MYH13
4629:MYH11
4624:MYH10
4609:MYH7B
4568:MYO1H
4563:MYO1G
4558:MYO1F
4553:MYO1E
4548:MYO1D
4543:MYO1C
4538:MYO1B
4533:MYO1A
4448:Human
4282:S2CID
3981:14854
3641:S2CID
3598:S2CID
3460:55321
3250:S2CID
3059:S2CID
2921:S2CID
2745:53904
1955:S2CID
1893:32266
1711:S2CID
1293:actin
1270:MYLL1
1266:MYLK2
1258:MYLIP
1246:MYL6B
1211:MYO19
1195:MYO16
1183:MYO10
1177:MYO9B
1173:MYO9A
1167:MYO7B
1163:MYO7A
1151:MYO5C
1147:MYO5B
1143:MYO5A
1137:MYO3B
1133:MYO3A
1127:MYH16
1123:MYH15
1119:MYH14
1115:MYH13
1111:MYH11
1107:MYH10
1095:MYH7B
1065:MYO1H
1061:MYO1G
1057:MYO1F
1053:MYO1E
1049:MYO1D
1045:MYO1C
1041:MYO1B
1037:MYO1A
813:actin
767:dimer
669:actin
602:dimer
558:MYO3A
502:gene.
492:17a/b
421:MYH11
317:genes
202:actin
140:genes
119:cells
96:actin
8112:Both
7906:NOS1
7773:SGCZ
7768:SGCG
7763:SGCE
7758:SGCD
7753:SGCB
7748:SGCA
7716:DAPC
7603:OPA1
7596:and
7548:EF-G
7538:IF-2
7504:Rheb
7492:ARL6
7477:ARF6
7448:NRAS
7443:KRAS
7438:HRAS
7423:RhoD
7418:RhoF
7364:RhoH
7340:RhoG
7325:Rac1
7313:RhoV
7308:RhoU
7291:TC10
7227:GNAQ
6947:SPCA
6774:3.6)
6708:ParM
6703:MreB
6698:FtsZ
6658:ACF7
6651:PKP2
6646:PKP1
6629:TLN1
6544:SPTB
6522:ANK3
6517:ANK2
6512:ANK1
6421:DNM3
6416:DNM2
6411:DNM1
6315:PCM1
5965:KIF9
5960:KIF7
5955:KIF6
5882:MAP4
5877:MAP2
5844:MAPs
5744:TUBB
5687:MAPs
5685:and
5626:NEFH
5621:NEFM
5616:NEFL
5575:GFAP
5223:none
5081:FLNC
5076:FLNB
5071:FLNA
4821:MYLK
4811:MYL9
4806:MYL7
4796:MYL6
4791:MYL5
4786:MYL4
4781:MYL3
4776:MYL2
4771:MYL1
4700:VII
4694:MYO6
4655:III
4619:MYH9
4614:MYH8
4604:MYH7
4599:MYH6
4594:MYH4
4589:MYH3
4584:MYH2
4579:MYH1
4461:ABPs
4459:and
4274:PMID
4245:PMID
4231:1496
4210:PMID
4181:PMID
4171:ISBN
4135:PMID
4084:PMID
4049:PMID
4015:2022
3986:PMID
3937:PMID
3888:PMID
3839:PMID
3790:PMID
3749:PMID
3692:PMID
3633:PMID
3590:PMID
3555:PMID
3514:PMID
3465:PMID
3412:ISBN
3389:PMID
3348:PMID
3299:PMID
3242:PMID
3224:Cell
3201:PMID
3149:PMID
3100:PMID
3051:PMID
3016:PMID
2978:PMID
2913:PMID
2878:PMID
2829:PMID
2780:PMID
2766:1496
2729:2015
2699:PMID
2640:PMID
2591:PMID
2532:PMID
2483:PMID
2426:PMID
2377:PMID
2320:PMID
2261:PMID
2204:PMID
2169:PMID
2134:PMID
2080:PMID
2031:PMID
1986:2007
1947:PMID
1898:PMID
1849:PMID
1814:PMID
1787:PMID
1746:PMID
1703:PMID
1660:PMID
1625:PMID
1617:ISSN
1580:ISBN
1558:PMID
1514:PMID
1465:PMID
1420:2016
1362:and
1325:clam
1262:MYLK
1254:MYL9
1250:MYL7
1242:MYL6
1238:MYL5
1234:MYL4
1230:MYL3
1226:MYL2
1222:MYL1
1157:MYO6
1103:MYH9
1099:MYH8
1091:MYH7
1087:MYH6
1083:MYH4
1079:MYH3
1075:MYH2
1071:MYH1
785:and
732:and
568:and
490:(MLC
416:neck
232:The
214:the
194:The
188:head
152:myo-
125:and
7734:DAP
7598:MX2
7594:MX1
7514:RGK
7509:Rap
7499:Ran
7472:Arf
7455:Rab
7433:Ras
7391:Rnd
7369:Rho
7320:Rac
7296:TCL
7157:olf
6889:Ca+
6472:GAN
6455:APC
5862:EB3
5857:EB2
5852:EB1
5658:A/C
5341:33B
5336:33A
4740:XV
4715:IX
4690:VI
4575:II
4266:doi
4235:doi
4202:doi
4163:doi
4125:PMC
4115:doi
4076:doi
4041:doi
3976:PMC
3968:doi
3927:PMC
3919:doi
3915:155
3878:PMC
3870:doi
3829:PMC
3821:doi
3817:146
3780:doi
3739:PMC
3731:doi
3682:PMC
3672:doi
3668:109
3625:doi
3582:doi
3545:doi
3504:PMC
3496:doi
3492:126
3455:PMC
3445:doi
3379:doi
3338:PMC
3330:doi
3289:PMC
3281:doi
3277:369
3232:doi
3228:131
3191:PMC
3183:doi
3139:PMC
3131:doi
3090:doi
3086:275
3043:doi
3008:doi
2968:PMC
2960:doi
2905:doi
2868:PMC
2860:doi
2856:122
2819:PMC
2811:doi
2807:139
2770:doi
2689:PMC
2679:doi
2667:108
2630:PMC
2622:doi
2618:151
2581:PMC
2571:doi
2559:108
2522:PMC
2514:doi
2510:151
2473:PMC
2465:doi
2453:588
2416:PMC
2408:doi
2404:151
2367:PMC
2359:doi
2347:588
2310:PMC
2300:doi
2288:108
2251:PMC
2243:doi
2231:588
2196:doi
2161:doi
2124:doi
2070:PMC
2062:doi
2021:PMC
2013:doi
1937:PMC
1929:doi
1888:PMC
1880:doi
1841:doi
1837:113
1777:doi
1738:doi
1695:doi
1683:534
1652:doi
1609:doi
1548:doi
1544:248
1504:PMC
1496:doi
1492:123
1455:PMC
1447:doi
1443:125
993:.
954:.
880:.
841:.
726:in
716:in
665:kDa
633:ATP
445:kDa
378:in
206:ATP
158:-in
92:ATP
74:of
8283::
7869:G2
7864:G1
7859:B2
7854:B1
7279::
7167:αi
7149:αs
7127::
6850::
6772:EC
6766::
5668:B2
5663:B1
5656::
5532:80
5527:79
5522:78
5517:77
5512:76
5507:75
5502:74
5497:73
5492:72
5487:71
5471:40
5466:39
5461:28
5456:27
5451:26
5446:25
5441:24
5436:23
5411:86
5406:85
5401:84
5396:83
5391:82
5386:81
5366:38
5361:37
5356:36
5351:35
5346:34
5331:32
5326:31
5283:6C
5278:6B
5273:6A
5253:2A
5228:21
5216:18
5202:20
5197:19
5192:17
5187:16
5182:15
5177:14
5172:13
5167:12
5162:10
4766:LC
4730:X
4670:V
4529:I
4512:G2
4507:G1
4502:C1
4492:A2
4487:A1
4393:EC
4280:.
4272:.
4262:30
4260:.
4243:.
4229:.
4225:.
4208:.
4198:11
4196:.
4179:.
4169:.
4133:.
4123:.
4111:27
4109:.
4105:.
4082:.
4072:56
4070:.
4047:.
4037:55
4035:.
4023:^
4006:.
3984:.
3974:.
3964:11
3962:.
3958:.
3935:.
3925:.
3913:.
3909:.
3886:.
3876:.
3866:22
3864:.
3860:.
3837:.
3827:.
3815:.
3811:.
3788:.
3774:.
3770:.
3747:.
3737:.
3729:.
3717:.
3713:.
3690:.
3680:.
3666:.
3662:.
3639:.
3631:.
3619:.
3596:.
3588:.
3576:.
3553:.
3541:19
3539:.
3535:.
3512:.
3502:.
3490:.
3486:.
3463:.
3453:.
3439:.
3435:.
3387:.
3375:25
3373:.
3369:.
3346:.
3336:.
3326:20
3324:.
3320:.
3297:.
3287:.
3275:.
3271:.
3248:.
3240:.
3226:.
3222:.
3199:.
3189:.
3177:.
3173:.
3161:^
3147:.
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