260:, for the discovery of RNA splicing. Roberts called the award a "tribute" to his co-workers, including Chow. However, other scientists felt that Chow, who operated the electron microscope that allowed researchers to observe the splicing process, should have been included among the scientists awarded the Nobel Prize for the research. Chow told the Boston Globe that her contributions "were not trivial
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In 1984, she took a job with the
University of Rochester School of Medicine, studying the genome of the human papillomavirus (HPV). Chow became a professor at the University of Alabama at Birmingham (UAB) in 1993, studying genetics and virology, focusing on diseases such as cancer, cystic fibrosis,
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She and her husband, fellow scientist Thomas Broker, joined Cold Spring Harbor
Laboratory in 1975. It was here that, in the process of studying the genetic organization, DNA transcription, and RNA translation of adenoviruses, she and her colleagues discovered
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in 1977. This finding led to her collaborator, Richard
Roberts, winning the 1993 Nobel Prize in Physiology or Medicine (shared with Phillip Sharp from MIT whose team independently made the discovery). Many feel that Chow deserved a share of the prize (see
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At UAB, Chow developed a method to produce large amounts of one of the most dominant cancer-causing HPV strains, HPV-18, in the laboratory, enabling her and her team to study HPV's entire replicative cycle.
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Chow, L. T.; Gelinas, R. E.; Broker, T. R.; Roberts, R. J. (September 1977). "An amazing sequence arrangement at the 5' ends of adenovirus 2 messenger RNA".
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Behind Nobel, A Struggle for
Recognition Some Scientists Say Colleague of Beverly Researcher Deserved A Share of Medical Prize
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In 1993, her collaborator at Cold Spring Harbor
Laboratory,
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Foreign associates of the
National Academy of Sciences
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16:Professor of biochemistry and molecular genetics
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450:"Ulf Pettersson on Rich Roberts' Nobel Prize"
536:. Archived from the original on June 6, 2004
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390:Thannickal, Beena (May 3, 2012).
164:and a foreign associate with the
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168:, known for her research on the
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234:Nobel Prize controversy
675:Chinese women chemists
700:Biologists from Hunan
680:Taiwanese biochemists
430:on September 25, 2021
695:Educators from Hunan
421:"Louise Chow, Ph.D."
170:human papillomavirus
152:) is a professor of
630:Chemists from Hunan
357:"周芷 Louis Tsi Chow"
480:American Scientist
254:Richard J. Roberts
174:Richard J. Roberts
158:molecular genetics
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71:RNA splicing
574:EurekAlert!
178:Nobel Prize
42:Citizenship
619:Categories
579:2018-03-20
540:2015-09-04
511:2018-10-18
486:2022-12-20
371:2018-10-18
340:References
332:Member of
282:(1): 1–8.
240:and AIDS.
296:0092-8674
188:Biography
184:as well.
549:cite web
149:Zhōu Zhǐ
48:(Taiwan)
501:"周芷小檔案"
312:2099968
160:at the
136:Chinese
36:, China
329:, 2012
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144:pinyin
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84:Fields
308:S2CID
34:Hunan
605:2015
555:link
462:2015
436:2015
400:2015
300:PMID
292:ISSN
276:Cell
221:SV40
156:and
29:Born
284:doi
236:).
202:周德偉
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