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Brett Finlay

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281:, and involves a multidisciplinary research program exploring how microbes contribute to both human health and disease. The lab specifically focuses on type III secreted virulence factors from Salmonella and pathogenic E. coli, how microbiota influence infectious diarrhea outcomes, and the role of the microbiota in asthma, malnutrition, and environmental enteropathy. One of his graduate students there was medical microbiologist 25: 220:
microbiologist well known for his contributions to understanding how microbes cause disease in people and developing new tools for fighting infections, as well as the role the microbiota plays in human health and disease. Science.ca describes him as one of the world's foremost experts on the
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molecular understanding of the ways bacteria infect their hosts. He also led the SARS Accelerated Vaccine Initiative (SAVI) and developed vaccines to SARS and a bovine vaccine to E. coli O157:H7. His current research interests focus on pathogenic
451:, about the critical role microbes play in early childhood development, having a major impact on both health and disease. It was published by Algonquin Books (USA) and Greystone (Canada) in Sept 2016, and is being translated into 11 languages 419:
Early infancy microbial and metabolic alterations affect risk of childhood asthma. Arrieta MC, Stiemsma LT, Dimitriu PA,; CHILD Study Investigators, Mohn WW, Turvey SE, Finlay BB, et al. Sci Transl Med. 2015 Sep 30;7(307):307ra152. doi:
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daughter Dr. Jessica Finlay focus on the teeming world of microbes everywhere in and around us. In this book, the Finlays suggest improvements to lifestyle, diet, and household practices to promote the right kind of microbial exposure.
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Vedanta Biosciences Inc., rationally design medicines based on consortia of human commensal bacteria to treat disease, using insights from microbial ecology, mucosal immunology, and human interventional
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Enteropathogenic E. coli (EPEC) transfers its receptor for intimate adherence into mammalian cells. B Kenny, R DeVinney, M Stein, DJ Reinscheid, EA Frey, BB Finlay. Cell 91 (4), 511-520
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Inimex Pharmaceuticals Inc., developer of medicines that use selective modulation of the innate immune response. The company's lead program was acquired by Soligenix.
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Diet and specific microbial exposure trigger features of environmental enteropathy in a novel murine model. Brown EM, Finlay BB, et al. Nat Commun. 2015 Aug 4;6:7806.
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2001–present Section Head (Cellular Microbiology and Pathogenesis) for Faculty 1000, an online service to organize and evaluate the life sciences literature
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Howard Hughes International Scholar, Fellow of the Royal Society of Canada, German National Academy of Sciences Leopoldina Foreign Member
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2010–present Editorial Advisory Panel (inaugural), Nature Communications, on-line multidisciplinary journal, Nature Publishing Group.
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Common themes in microbial pathogenicity revisited. BB Finlay, S Falkow. Microbiology and Molecular Biology Reviews 61 (2), 136-169
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Microbiome Insights Inc., leading microbiome testing company focused on next generation sequencing and bioinformatic analysis
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Commense, focused on preventing and treating disease through microbiome-based interventions in infancy and early childhood
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Manipulation of host-cell pathways by bacterial pathogens. AP Bhavsar, JA Guttman, BB Finlay. Nature 449 (7164), 827-834
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Exploitation of mammalian host cell functions by bacterial pathogens. BB Finlay, P Cossart. Science 276 (5313), 718-725
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Molecular mechanisms of Escherichia coli pathogenicity. MA Croxen, BB Finlay. Nature Reviews Microbiology 8 (1), 26-38
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2009 Editor, Future Microbiology Special Focus Issue: The molecular basis of pathogenesis: proteomics and beyond.
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February 2011 Section Editor, Current Opinion in Microbiology, Section: Host-microbe interactions: Bacteria.
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Finlay's lab is based in Vancouver, British Columbia, Canada in the Michael Smith Laboratories at the
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The Whole-Body Microbiome: How to harness microbes - inside and out - for lifelong health
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The Whole-Body Microbiome: How to Harness Microbes - Inside and Out - For Lifelong Health
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Sekirov, Inna; Russell, Shannon L.; Antunes, L. Caetano M.; Finlay, B. Brett (2010).
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Finlay received his B.Sc.(Honors) (1981) and Ph.D. (1986) in Biochemistry from the
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Finlay has co-authored, with Marie-Claire Arrieta, a book for general audiences,
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1993-97 Editor, Infection and Immunity section, Canadian Journal of Microbiology
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Parts of the article are written in an inappropriate, advertisement-style tone.
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Michael Smith Laboratories, Vancouver Campus, University of British Columbia
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1999–present Advisory Board, International Journal of Medical Microbiology
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2003 Section Editor (Cytology), American Society for Microbiology book, "
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2000–present Editorial Board, Current Drug Targets - Infectious Disorders
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Howard Hughes International Research Scholar 1991, 1997, 1999, 2000, 2001
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1992-1999 Trends in Microbiology: Infection, Virulence, and Pathogenesis
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2009–present Editorial Board, mBio, American Society for Microbiology
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2005-2008 Reviews Editor, PLoS (Public Library of Science) Pathogens
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Finlay has been a scientific founder of the following companies:
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Let Them Eat Dirt: Saving your child from an oversanitized world
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Let Them Eat Dirt: Saving Your Child from an Oversanitized World
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2000-2003 Editor, Infection and Immunity (20 manuscripts/month)
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2011–present Member, Senior Medical Expert Panel, Nature Index
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Humans and Microbes program. He is also co-author of the book
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1997–present Editorial Board, Current Opinion in Microbiology
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2005–present Editorial Advisory Panel, Future Microbiology
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2006–present Editorial Board, Cell Host & Microbe
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Academic staff of the University of British Columbia
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1998–present Editorial Board, Microbes and Infection
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1999–present Editorial Board, Cellular Microbiology
170:Studies on transfer genes from IncF plasmids. 1986 950:"Past Award Winners | The Royal Society of Canada" 481:1997-2005 Editorial Board, Molecular Microbiology 2238: 1189:"Q & A with Dr. Brett Finlay, Co-Author of 1072:"Milestones in Canadian Health Research - CIHR" 555:2013–present Senior Editor, Future Microbiology 478:1994-02 Editorial Board, Infection and Immunity 356:Fellow of the Canadian Academy of Sciences 2005 313:German National Academy of Sciences Leopoldina 1365: 508:2001–present Editorial Board, Current Biology 1186: 1170:by B. Brett Finlay and Marie-Claire Arrieta" 710:"Brett Finlay | Michael Smith Laboratories" 558:2013–present Associate Editor, Gut Microbes 534:2009–present Associate Editor, Gut Microbes 438:More publications may be accessed at PubMed 1372: 1358: 1129:Peter Wall Institute for Advanced Studies 758:"Finlay Lab - Michael Smith Laboratories" 684:Peter Wall Institute for Advanced Studies 68:Learn how and when to remove this message 2272:Members of the Order of British Columbia 1149:Search Results for author Finlay BB 410: 319:Queen Elizabeth II Diamond Jubilee Medal 762:Finlay Lab - Michael Smith Laboratories 368:Canadian Institutes for Health Research 2262:Fellows of the Royal Society of Canada 2239: 783:"Gut microbiota in health and disease" 361:Infectious Diseases Society of America 1353: 353:Killam Prize for Health Sciences 2006 397:CIHR Distinguished Investigator 2001 261:, and did his post-doctoral work at 18: 627:"science.ca : B. Brett Finlay" 603:"science.ca : B. Brett Finlay" 561:2014–present Trends in Microbiology 229:pathogenicity, and the role of the 13: 2252:20th-century Canadian male writers 531:2007–present Editorial Board, PNAS 487:1997-2010 Editorial Board, Traffic 382:Peter Wall Distinguished Professor 14: 2308: 1329: 295:The Canadian Medical Hall of Fame 1187:Solhi, Laleh (January 2, 2019). 979:"The Governor General of Canada" 546:2010–present Section Head, F1000 375:American Academy of Microbiology 366:CIHR Michael Smith Prize of the 121:Work on mechanisms of microbial 23: 2277:Officers of the Order of Canada 1301: 1276: 1252: 1228: 1203: 1180: 1158: 1142: 1117: 1093: 1064: 1039: 1015: 991: 971: 942: 918: 894: 870: 846: 829:"ANNOUNCING THE 2018 INDUCTEES" 458:, Finlay and his environmental 878:"B. Brett Finlay : CIFAR" 821: 774: 750: 734:"B. Brett Finlay : CIFAR" 726: 702: 672: 643: 619: 595: 466: 279:University of British Columbia 1: 1382:Canadian Medical Hall of Fame 833:Canadian Medical Hall of Fame 588: 2287:University of Alberta alumni 1309:"Microbiome Insights - Team" 686:. 2016-08-17. Archived from 420:10.1126/scitranslmed.aab2271 252: 7: 2221:Marie-Marguerite d'Youville 565: 233:in infections, asthma, and 43:. The specific problem is: 10: 2313: 2282:Stanford University alumni 858:eng.prix-galien-canada.com 799:10.1152/physrev.00045.2009 657:. May 2009. Archived from 272: 1951:Jonathan Campbell Meakins 1388: 1191:The Whole-Body Microbiome 288: 216:(born 4 April 1959) is a 179: 175: 163: 156: 148: 140: 132: 117: 106: 89: 82: 2257:Canadian microbiologists 2061:Cheryl Rockman-Greenberg 1996:William Thornton Mustard 1863:Charles Philippe Leblond 442: 309:CIFAR Senior Fellow 2014 1559:William Arthur Cochrane 1101:"Navigation for iFrame" 930:www.orderofbc.gov.bc.ca 392:Royal Society of Canada 341:Royal Society of Canada 16:Canadian microbiologist 2162:Lucille Teasdale-Corti 1976:Frederick Montizambert 1481:Wilfred Gordon Bigelow 2297:Writers from Edmonton 1337:Whole body microbiome 787:Physiological Reviews 411:Selected publications 259:University of Alberta 111:University of Alberta 2119:F. Estelle R. Simons 1617:Charles George Drake 1544:Harvey Max Chochinov 1288:www.businesswire.com 1260:"Board and Advisors" 50:improve this article 39:to meet Knowledge's 2076:Jean-Lucien Rouleau 1764:Emmett Matthew Hall 1574:Douglas Harold Copp 1436:Charles Thomas Beer 1426:Henry J. M. Barnett 1380:Inductees into the 1313:Microbiome Insights 1240:Vedanta Biosciences 1076:www.cihr-irsc.gc.ca 315:Foreign Member 2012 304:Carnegie Fellowship 263:Stanford University 2182:Sir Charles Tupper 2124:Duncan G. Sinclair 1986:Thomas John Murray 1814:Charles B. Huggins 1799:Charles Hollenberg 1779:Donald Olding Hebb 1769:Judith Goslin Hall 1754:Vladimir Hachinski 1678:John G. FitzGerald 1456:Michel G. Bergeron 906:www.leopoldina.org 2234: 2233: 2114:Louis Siminovitch 1774:Michael R. Hayden 1731:Richard Goldbloom 1645:John Robert Evans 1622:Daniel J. Drucker 1496:Adolfo J. de Bold 1421:Frederick Banting 1416:Elizabeth Bagshaw 1344:Let them eat dirt 1168:Let Them Eat Dirt 1047:"UBC News Digest" 902:"List of Members" 406:Fisher Prize 1991 326:College de France 197: 196: 158:Scientific career 78: 77: 70: 41:quality standards 32:This article may 2304: 2187:D. Lorne Tyrrell 2139:Bette Stephenson 2099:Robert B. Salter 2022:Annette O'Connor 1941:Joseph B. Martin 1901:Walter Mackenzie 1891:Ernest McCulloch 1827:David J. Jenkins 1741:Wilfred Grenfell 1673:C. Miller Fisher 1597:Thomas A. Dignan 1516:G. Malcolm Brown 1491:Stephen Blizzard 1476:John Bienenstock 1451:Philip B. Berger 1374: 1367: 1360: 1351: 1350: 1323: 1322: 1320: 1319: 1305: 1299: 1298: 1296: 1295: 1280: 1274: 1273: 1271: 1270: 1256: 1250: 1249: 1247: 1246: 1232: 1226: 1225: 1223: 1222: 1207: 1201: 1200: 1184: 1178: 1177: 1162: 1156: 1146: 1140: 1139: 1137: 1136: 1121: 1115: 1114: 1112: 1111: 1105:accounts.asm.org 1097: 1091: 1090: 1088: 1087: 1078:. Archived from 1068: 1062: 1061: 1059: 1058: 1043: 1037: 1036: 1034: 1028:. Archived from 1027: 1019: 1013: 1012: 1010: 1009: 995: 989: 988: 986: 985: 975: 969: 968: 966: 965: 956:. Archived from 946: 940: 939: 937: 936: 922: 916: 915: 913: 912: 898: 892: 891: 889: 888: 874: 868: 867: 865: 864: 854:"2014 Laureates" 850: 844: 843: 841: 839: 825: 819: 818: 778: 772: 771: 769: 768: 754: 748: 747: 745: 744: 730: 724: 723: 721: 720: 706: 700: 699: 697: 695: 676: 670: 669: 667: 666: 647: 641: 640: 638: 637: 623: 617: 616: 614: 613: 599: 300:Prix Galien 2014 215: 193: 190: 188: 186: 80: 79: 73: 66: 62: 59: 53: 27: 26: 19: 2312: 2311: 2307: 2306: 2305: 2303: 2302: 2301: 2237: 2236: 2235: 2230: 2134:Nahum Sonenberg 2104:Charles Scriver 2071:Noralou P. Roos 2040:Wilder Penfield 1911:David MacLennan 1868:Maurice LeClair 1832:Harold E. Johns 1789:FĂ©lix d'Herelle 1721:Gustave Gingras 1693:Armand Frappier 1663:William Feindel 1653:Ray Farquharson 1592:Naranjan Dhalla 1554:Michel ChrĂ©tien 1534:Elaine A. Carty 1446:Bernard Belleau 1384: 1378: 1332: 1327: 1326: 1317: 1315: 1307: 1306: 1302: 1293: 1291: 1282: 1281: 1277: 1268: 1266: 1258: 1257: 1253: 1244: 1242: 1234: 1233: 1229: 1220: 1218: 1209: 1208: 1204: 1185: 1181: 1164: 1163: 1159: 1147: 1143: 1134: 1132: 1123: 1122: 1118: 1109: 1107: 1099: 1098: 1094: 1085: 1083: 1070: 1069: 1065: 1056: 1054: 1045: 1044: 1040: 1032: 1025: 1021: 1020: 1016: 1007: 1005: 997: 996: 992: 983: 981: 977: 976: 972: 963: 961: 948: 947: 943: 934: 932: 924: 923: 919: 910: 908: 900: 899: 895: 886: 884: 876: 875: 871: 862: 860: 852: 851: 847: 837: 835: 827: 826: 822: 779: 775: 766: 764: 756: 755: 751: 742: 740: 732: 731: 727: 718: 716: 708: 707: 703: 693: 691: 678: 677: 673: 664: 662: 649: 648: 644: 635: 633: 625: 624: 620: 611: 609: 601: 600: 596: 591: 568: 469: 445: 413: 348:Order of Canada 291: 275: 255: 203: 200:B. Brett Finlay 183: 107:Alma mater 102: 85: 74: 63: 57: 54: 47: 28: 24: 17: 12: 11: 5: 2310: 2300: 2299: 2294: 2289: 2284: 2279: 2274: 2269: 2264: 2259: 2254: 2249: 2232: 2231: 2229: 2228: 2223: 2218: 2210: 2205: 2200: 2192: 2184: 2179: 2174: 2169: 2164: 2159: 2154: 2146: 2144:Calvin Stiller 2141: 2136: 2131: 2126: 2121: 2116: 2111: 2106: 2101: 2096: 2091: 2083: 2078: 2073: 2068: 2063: 2058: 2050: 2042: 2037: 2035:Anthony Pawson 2032: 2024: 2019: 2011: 2006: 2004:Arnold Naimark 2001: 1993: 1991:Fraser Mustard 1988: 1983: 1978: 1973: 1971:Julio Montaner 1968: 1963: 1961:Ronald Melzack 1958: 1953: 1948: 1943: 1938: 1933: 1928: 1923: 1918: 1913: 1908: 1903: 1898: 1896:John McEachern 1893: 1888: 1883: 1878:Peter Lougheed 1875: 1870: 1865: 1860: 1858:Bernard Langer 1855: 1850: 1842: 1837: 1829: 1824: 1822:Herbert Jasper 1819: 1811: 1806: 1801: 1796: 1791: 1786: 1781: 1776: 1771: 1766: 1761: 1756: 1751: 1743: 1738: 1733: 1728: 1723: 1718: 1716:Jacques Genest 1713: 1711:William Gallie 1708: 1700: 1695: 1690: 1685: 1683:Claude Fortier 1680: 1675: 1670: 1665: 1660: 1658:Sylvia Fedoruk 1655: 1650: 1642: 1637: 1629: 1627:Jacalyn Duffin 1624: 1619: 1614: 1609: 1604: 1599: 1594: 1589: 1584: 1576: 1571: 1566: 1561: 1556: 1551: 1546: 1541: 1539:Brock Chisholm 1536: 1531: 1526:Alan C. Burton 1523: 1518: 1513: 1508: 1503: 1501:Roberta Bondar 1498: 1493: 1488: 1483: 1478: 1473: 1471:Norman Bethune 1468: 1463: 1461:Alan Bernstein 1458: 1453: 1448: 1443: 1438: 1433: 1428: 1423: 1418: 1413: 1405: 1400: 1395: 1389: 1386: 1385: 1377: 1376: 1369: 1362: 1354: 1348: 1347: 1340: 1331: 1330:External links 1328: 1325: 1324: 1300: 1275: 1251: 1236:"Brett Finlay" 1227: 1202: 1179: 1174:Kirkus Reviews 1157: 1141: 1125:"Brett Finlay" 1116: 1092: 1063: 1038: 1035:on 2017-09-12. 1014: 990: 970: 941: 917: 893: 869: 845: 820: 793:(3): 859–904. 773: 749: 725: 714:www.msl.ubc.ca 701: 680:"Brett Finlay" 671: 642: 631:www.science.ca 618: 607:www.science.ca 593: 592: 590: 587: 586: 585: 582: 579: 575: 567: 564: 563: 562: 559: 556: 553: 550: 547: 544: 541: 538: 535: 532: 529: 526: 523: 520: 509: 506: 503: 500: 497: 494: 491: 488: 485: 482: 479: 476: 473: 468: 465: 444: 441: 440: 439: 436: 433: 430: 427: 424: 421: 417: 412: 409: 408: 407: 404: 398: 395: 390:Fellow of the 388: 385: 378: 373:Fellow of the 371: 364: 359:Squibb Award, 357: 354: 351: 344: 338:Flavelle Medal 335: 329: 322: 316: 310: 307: 301: 298: 290: 287: 274: 271: 267:Stanley Falkow 254: 251: 195: 194: 181: 177: 176: 173: 172: 167: 161: 160: 154: 153: 150: 146: 145: 142: 138: 137: 134: 130: 129: 119: 118:Known for 115: 114: 108: 104: 103: 93: 91: 87: 86: 83: 76: 75: 31: 29: 22: 15: 9: 6: 4: 3: 2: 2309: 2298: 2295: 2293: 2290: 2288: 2285: 2283: 2280: 2278: 2275: 2273: 2270: 2268: 2267:Living people 2265: 2263: 2260: 2258: 2255: 2253: 2250: 2248: 2245: 2244: 2242: 2227: 2224: 2222: 2219: 2217: 2214: 2213:Ronald Worton 2211: 2209: 2206: 2204: 2203:Mark Wainberg 2201: 2199: 2196: 2195:Mladen Vranic 2193: 2191: 2188: 2185: 2183: 2180: 2178: 2177:Endel Tulving 2175: 2173: 2172:Lap-Chee Tsui 2170: 2168: 2165: 2163: 2160: 2158: 2157:Charles Tator 2155: 2153: 2150: 2147: 2145: 2142: 2140: 2137: 2135: 2132: 2130: 2129:Michael Smith 2127: 2125: 2122: 2120: 2117: 2115: 2112: 2110: 2107: 2105: 2102: 2100: 2097: 2095: 2094:David Sackett 2092: 2090: 2087: 2084: 2082: 2079: 2077: 2074: 2072: 2069: 2067: 2064: 2062: 2059: 2057: 2054: 2051: 2049: 2046: 2043: 2041: 2038: 2036: 2033: 2031: 2028: 2027:William Osler 2025: 2023: 2020: 2018: 2015: 2012: 2010: 2007: 2005: 2002: 2000: 1997: 1994: 1992: 1989: 1987: 1984: 1982: 1981:Balfour Mount 1979: 1977: 1974: 1972: 1969: 1967: 1966:Brenda Milner 1964: 1962: 1959: 1957: 1954: 1952: 1949: 1947: 1946:Pierre Masson 1944: 1942: 1939: 1937: 1934: 1932: 1929: 1927: 1926:Ian McWhinney 1924: 1922: 1919: 1917: 1914: 1912: 1909: 1907: 1906:Peter Macklem 1904: 1902: 1899: 1897: 1894: 1892: 1889: 1887: 1884: 1882: 1879: 1876: 1874: 1873:Heinz Lehmann 1871: 1869: 1866: 1864: 1861: 1859: 1856: 1854: 1851: 1849: 1846: 1843: 1841: 1838: 1836: 1833: 1830: 1828: 1825: 1823: 1820: 1818: 1815: 1812: 1810: 1807: 1805: 1804:James C. 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Edmonton
Alberta
University of Alberta
pathogenicity
microbiota
Thesis
finlaylab.msl.ubc.ca
OC
OBC
FRSC
Canadian
E. coli
Salmonella
microbiota
malnutrition
CIFAR
University of Alberta
Stanford University
Stanley Falkow
University of British Columbia
Inna Sekirov
The Canadian Medical Hall of Fame
Carnegie Fellowship
German National Academy of Sciences Leopoldina
Queen Elizabeth II Diamond Jubilee Medal
College de France

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