Knowledge

Lactic acid

Source πŸ“

2179: 511: 281: 53: 889: 44: 943: 2162:, lactate, and pyruvate act as oxidative energy substrates, causing an increase in the NAD(P)H oxidation phase, that glucose was insufficient as an energy carrier during intense synaptic activity and, finally, that lactate can be an efficient energy substrate capable of sustaining and enhancing brain aerobic energy metabolism 2495:
E270. Lactic acid is used as a food preservative, curing agent, and flavoring agent. It is an ingredient in processed foods and is used as a decontaminant during meat processing. Lactic acid is produced commercially by fermentation of carbohydrates such as glucose, sucrose, or lactose, or by chemical
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during production of pyruvate from glucose, and this ensures that energy production is maintained and exercise can continue. During intense exercise, the respiratory chain cannot keep up with the amount of hydrogen ions that join to form NADH, and cannot regenerate NAD quickly enough, so pyruvate is
2166:. The study "provides novel data on biphasic NAD(P)H fluorescence transients, an important physiological response to neural activation that has been reproduced in many studies and that is believed to originate predominantly from activity-induced concentration changes to the cellular NADH pools." 1807:
Lactate is continually formed at rest and during all exercise intensities. Lactate serves as a metabolic fuel being produced and oxidatively disposed in resting and exercising muscle and other tissues. Some sources of excess lactate production are metabolism in
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when the flow of blood is limited as in sepsis or hemorrhagic shock. It may also occur when demand for oxygen is high such as with intense exercise. Lactic acidosis results in an oxygen debt which can be resolved or repaid when tissue oxygenation improves.
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generates ATP for use in powering the cell. When insufficient oxygen is present, or when there is insufficient capacity for pyruvate oxidation to keep up with rapid pyruvate production during intense exertion, the pyruvate is converted to lactate by
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may use the standard 4 kilocalories (17 kJ) per gram that is often used for all carbohydrates. But in some cases lactic acid is ignored in the calculation. The energy density of lactic acid is 362 kilocalories (1,510 kJ) per 100 g.
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the food energy is calculated using given coefficients for carbohydrate, fat, and protein. (One must click on "Full report" to see the coefficients.) The calculated value is based on 4.66 grams of carbohydrate, which is exactly equal to the
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Silva AM, Kong X, Hider RC (October 2009). "Determination of the pKa value of the hydroxyl group in the alpha-hydroxycarboxylates citrate, malate and lactate by 13C NMR: implications for metal coordination in biological systems".
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Tyzio R, Allene C, Nardou R, Picardo MA, Yamamoto S, Sivakumaran S, Caiati MD, Rheims S, Minlebaev M, Milh M, FerrΓ© P, Khazipov R, Romette JL, Lorquin J, Cossart R, Khalilov I, Nehlig A, Cherubini E, Ben-Ari Y (January 2011).
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lactic acid might be included under the term "carbohydrate" (or "carbohydrate by difference") because this often includes everything other than water, protein, fat, ash, and ethanol. If this is the case then the calculated
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forms as a by-product; the Japanese company Musashino is one of the last big manufacturers of lactic acid by this route. Synthesis of both racemic and enantiopure lactic acids is also possible from other starting materials
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Ferguson, Brian S.; Rogatzki, Matthew J.; Goodwin, Matthew L.; Kane, Daniel A.; Rightmire, Zachary; Gladden, L. Bruce (2018). "Lactate metabolism: historical context, prior misinterpretations, and current understanding".
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Lactate can also serve as an important source of energy for other organs, including the heart and liver. During physical activity, up to 60% of the heart muscle's energy turnover rate derives from lactate oxidation.
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subjects, with lactate at these stages having higher concentrations in body liquids, and being utilized by the brain preferentially over glucose. It was also hypothesized that lactate may exert a strong action over
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is 1 unit less, meaning lactic acid is ten times more acidic than acetic acid. This higher acidity is the consequence of the intramolecular hydrogen bonding between the Ξ±-hydroxyl and the carboxylate group.
1608:(Hexose sugar) can be used. Pure sucrose, glucose from starch, raw sugar, and beet juice are frequently used. Lactic acid producing bacteria can be divided in two classes: homofermentative bacteria like 4535: 869: 2437:. Most commonly, this is produced naturally by various strains of bacteria. These bacteria ferment sugars into acids, unlike the yeast that ferment sugar into ethanol. After cooling the 3353:
Groot W, van Krieken J, Slekersl O, de Vos S (19 October 2010). "Chemistry and production of lactic acid, lactide and poly(lactic acid)". In Auras R, Lim LT, Selke SE, Tsuji H (eds.).
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Pellerin L, Bouzier-Sore AK, Aubert A, Serres S, Merle M, Costalat R, Magistretti PJ (September 2007). "Activity-dependent regulation of energy metabolism by astrocytes: an update".
2742: 1741:, and lactate is then produced from the pyruvate faster than the body can process it, causing lactate concentrations to rise. The production of lactate is beneficial for 6270: 4528: 925: 4114:
Campieri, C.; Campieri, M.; Bertuzzi, V.; Swennen, E.; Matteuzzi, D.; Stefoni, S.; Pirovano, F.; Centi, C.; Ulisse, S.; Famularo, G.; De Simone, C. (September 2001).
1196:. It does not increase in concentration until the rate of lactate production exceeds the rate of lactate removal, which is governed by a number of factors, including 6564: 6405: 6361: 5694: 2905:"International Union of Basic and Clinical Pharmacology. LXXXII: Nomenclature and Classification of Hydroxy-carboxylic Acid Receptors (GPR81, GPR109A, and GPR109B)" 2106:
cells are responsible for transforming glucose into lactate, and for providing lactate to the neurons. Because of this local metabolic activity of glial cells, the
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with water. When in the dissolved state, it forms a colorless solution. Production includes both artificial synthesis as well as natural sources. Lactic acid is an
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is usually assumed to be the main energy source for living tissues, there is evidence that lactate, in preference to glucose, is preferentially metabolized by
6607: 6586: 6471: 6427: 6383: 6016: 5984: 5781: 5607: 5530: 5317: 5274: 4521: 3781:"Energy substrate availability as a determinant of neuronal resting potential, GABA signaling and spontaneous network activity in the neonatal cortex in vitro" 6542: 6449: 6248: 6087: 6065: 5865: 1146:-lactic acid have a higher melting point. Lactic acid produced by fermentation of milk is often racemic, although certain species of bacteria produce solely 834: 1616:, producing two moles of lactate from one mole of glucose, and heterofermentative species producing one mole of lactate from one mole of glucose as well as 6040: 5651: 5447: 2772:"Skeletal muscle PGC-1Ξ± controls whole-body lactate homeostasis through estrogen-related receptor Ξ±-dependent activation of LDH B and repression of LDH A" 5469: 5403: 5043: 2055:
The resulting increase in acidity persists until the excess lactate and protons are converted back to pyruvate, and then to glucose for later use, or to
6105: 5565: 5233: 5091: 4498: 956: 5919: 5887: 3405: 6141: 5937: 1997:), when viewed in isolation, releases two H. The H are absorbed in the production of ATP, but H is subsequently released during hydrolysis of ATP: 3600:
Zilberter Y, Zilberter T, Bregestovski P (September 2010). "Neuronal activity in vitro and the in vivo reality: the role of energy homeostasis".
1468:. As of 2009, lactic acid was produced predominantly (70–90%) by fermentation. Production of racemic lactic acid consisting of a 1:1 mixture of 2208:), because lactate levels differ substantially between arterial and venous, and the arterial level is more representative for this purpose. 1564: 550: 4180: 1532: 4477: 4427: 2349:
to produce water-soluble lactates from otherwise-insoluble active ingredients. It finds further use in topical preparations and
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that perform aerobic respiration, and limitations in the rates of enzyme activity in muscle fibers during intense exertion.
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than it was previously assumed, acting either through better support of metabolites, or alterations in base intracellular
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Lactic acid is produced in human tissues when the demand for oxygen is limited by the supply. This occurs during tissue
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Lactic acid has historically been used to assist with the erasure of inks from official papers to be modified during
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in fermented milk is coagulated (curdled) by lactic acid. Lactic acid is also responsible for the sour flavor of
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H. Benninga (1990): "A History of Lactic Acid Making: A Chapter in the History of Biotechnology". Volume 11 of
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Khakhalin AS (September 2011). "Questioning the depolarizing effects of GABA during early brain development".
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Shuklov IA, Dubrovina NV, KΓΌhlein K, BΓΆrner A (2016). "Chemo-Catalyzed Pathways to Lactic Acid and Lactates".
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regeneration (pyruvate is reduced to lactate while NADH is oxidized to NAD), which is used up in oxidation of
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Robergs RA, Ghiasvand F, Parker D (September 2004). "Biochemistry of exercise-induced metabolic acidosis".
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As a starting material for industrial production of lactic acid, almost any carbohydrate source containing
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In winemaking, a bacterial process, natural or controlled, is often used to convert the naturally present
1152:-lactic acid. On the other hand, lactic acid produced by anaerobic respiration in animal muscles has the ( 6737: 3636: 1197: 1185: 1134:
with water and with ethanol above its melting point, which is about 16 to 18 Β°C (61 to 64 Β°F).
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While not normally found in significant quantities in fruit, lactic acid is the primary organic acid in
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Some evidence suggests that lactate is important at early stages of development for brain metabolism in
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In 2006, global production of lactic acid reached 275,000 tonnes with an average annual growth of 10%.
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Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 (Blue Book)
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it is approved for use in the EU, United States and Australia and New Zealand; it is listed by its
1547: 1523: 1265: 506: 3831:"Depolarizing actions of GABA in immature neurons depend neither on ketone bodies nor on pyruvate" 2185:, comparing lactate content (shown in violet at center-right) to other constituents in human blood 4936: 4491: 2542: 2461: 2417: 2201: 1500: 760: 1408: 186: 6727: 4968: 4708: 4645: 1830:-lactate), with formation of an excessively high proton concentration and correspondingly low 1724: 1313: 3074:
Aas JA, Griffen AL, Dardis SR, Lee AM, Olsen I, Dewhirst FE, Leys EJ, Paster BJ (April 2008).
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Holmgren CD, Mukhtarov M, Malkov AE, Popova IY, Bregestovski P, Zilberter Y (February 2010).
2557: 2193: 1906: 1181: 1083: 897: 881: 3250: 3233: 1200:, concentration and isoform of LDH, and oxidative capacity of tissues. The concentration of 2783: 2465: 2159: 1442: 1386: 1269: 460: 446: 439: 258: 137: 71: 4132: 4116:"Reduction of oxaluria after an oral course of lactic acid bacteria at high concentration" 4115: 2726: 1797:
If blood glucose concentrations are high, the glucose can be used to build up the liver's
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When sufficient oxygen is present for aerobic respiration, the pyruvate is oxidized to
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Offermanns S, Colletti SL, Lovenberg TW, Semple G, Wise A, IJzerman AP (June 2011).
2704: 1486:-lactic acid, is possible by microbial fermentation. Industrial scale production of 5382: 5069: 4448:
Sustainable Agriculture Reviews 34: Date Palm for Food Medicine and the Environment
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Offermanns S, Colletti SL, IJzerman AP, Lovenberg TW, Semple G, Wise A, Waters MG.
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to lactic acid, to reduce the sharpness and for other flavor-related reasons. This
1730: 1704: 1641: 1250: 1110:)-lactic acid, or (βˆ’)-lactic acid. A mixture of the two in equal amounts is called 845: 639: 573: 3552:
American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
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Lactic acid bacteria in Biology of Microorganisms on Grapes, in Must and in Wine
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Proceedings of the National Academy of Sciences of the United States of America
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Nascimento MM, Gordan VV, Garvan CW, Browngardt CM, Burne RA (April 2009).
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immediately surrounding neurons strongly differs in composition from the
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Parks, Scott K.; Mueller-Klieser, Wolfgang; PouyssΓ©gur, Jacques (2020).
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Once the production and use of ATP is included, the overall reaction is
1402: 1158:) enantiomer and is sometimes called "sarcolactic" acid, from the Greek 1040:
In solution, it can ionize by a loss of a proton to produce the lactate
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Li, Li; Yao, Xiaohong; Zhong, Caihong; Chen, Xuzhong (January 2010).
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Summermatter S, Santos G, PΓ©rez-Schindler J, Handschin C (May 2013).
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synthesis. Carbohydrate sources include corn, beets, and cane sugar.
2430: 2410: 2350: 2330: 2316: 2135: 2083: 1761: 1492:-lactic acid by fermentation is possible, but much more challenging. 1325: 1285: 1159: 478: 3969: 2976:"Ecology of lactobacilli in the oral cavity: a review of literature" 933:
Except where otherwise noted, data are given for materials in their
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Wyss MT, Jolivet R, Buck A, Magistretti PJ, Weber B (May 2011).
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Lactic acid containing bacteria have shown promise in reducing
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in the liver and release back into circulation by means of the
1769: 1596: 1418: 1328: 1321: 1178: 229: 3599: 3352: 3231: 2600:"CHAPTER P-6. Applications to Specific Classes of Compounds". 1389:
was the first person to isolate lactic acid in 1780 from sour
4353:"Listing of Specific Substances Affirmed as GRAS:Lactic Acid" 4330:. Australia New Zealand Food Standards Code. 8 September 2011 3878:
Ruusuvuori E, Kirilkin I, Pandya N, Kaila K (November 2010).
3877: 3778: 3689:"Lactate metabolism: a new paradigm for the third millennium" 3525:
Exercise Physiology: Energy, Nutrition, and Human Performance
3437: 2942: 2940: 2850: 2433:) purposely contain lactic acid, one such type being Belgian 2398: 2386: 2111: 2095: 2087: 2079: 1350: 1347: 1339: 1335: 1297: 1289: 1201: 414: 209: 157: 2851:
Goodwin ML, Harris JE, HernΓ‘ndez A, Gladden LB (July 2007).
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Racemic lactic acid is synthesized industrially by reacting
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Ivanov A, Mukhtarov M, Bregestovski P, Zilberter Y (2011).
3529:. Wolters Kluwer/Lippincott Williams & Wilkins Health. 3473: 2567: 2438: 2382: 2340: 2140: 2103: 1508: 1504: 1390: 1293: 355: 3637:"In vivo evidence for lactate as a neuronal energy source" 3634: 3122: 2937: 2333:. PLA is an example of a plastic that is not derived from 4199: 3403:
Westhoff, Gerrit; Starr, John N. (2012). "Lactic Acids".
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for lactate are performed to determine the status of the
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Derived from mass values using molar mass of 90.08 g/mol
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InChI=1S/C3H6O3/c1-2(4)3(5)6/h2,4H,1H3,(H,5,6)/t2-/m0/s1
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Two molecules of lactic acid can be dehydrated to the
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group. It is used as a synthetic intermediate in many
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Food Composition Data: Production, Management and Use
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Achanti, Anand; Szerlip, Harold M. (1 January 2023).
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characterized by accumulation of lactate (especially
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mM afterward. In addition to other biological roles,
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with its descaling properties on calcium compounds.
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to lactic acid. These bacteria can also grow in the
903: 4401:"Agency Response Letter GRAS Notice No. GRN 000240" 4284:"Current EU approved additives and their E Numbers" 4193: 3174:"Acid-Base Disorders in the Critically Ill Patient" 3073: 2285:, lactate levels in the fetus can be quantified by 1750:converted to lactate to allow energy production by 1438:. This pathway was used commercially by the German 343: 4347: 4345: 3522: 3294:"NNFCC Renewable Chemicals Factsheet: Lactic Acid" 3123:Caufield PW, Li Y, Dasanayake A, Saxena D (2007). 2118:, being much richer with lactate, as was found in 1456:Lactic acid is produced industrially by bacterial 1434:in the synthesis of lactic acid was discovered by 1421:during exertion. Its structure was established by 4444: 3520: 2516:Lactic acid is used in some liquid cleaners as a 185: 6704: 3595: 3593: 3591: 3589: 3469: 3467: 3465: 3463: 3461: 1669:, etc.) by application of catalytic procedures. 1029:(or the lactate anion). The name of the derived 402: 4342: 4100: 4098: 4096: 4094: 3516: 3514: 2125: 1845:, the conversion of glucose to pyruvate and H: 1757:The resulting lactate can be used in two ways: 1480:stereoisomers, or of mixtures with up to 99.9% 136: 122: 115: 4249: 3406:Ullmann's Encyclopedia of Industrial Chemistry 3171: 2673: 2065: 1733:, when the rate of demand for energy is high, 4969: 4529: 4252:"Akebia: A Potential New Fruit Crop in China" 3586: 3458: 3402: 3377: 1503:are obtained industrially by fermentation of 4428:"If I Sleep for an Hour, 30 People Will Die" 4187: 4091: 4074: 4072: 4070: 4068: 3511: 2973: 2648:Institute for Occupational Safety and Health 1223:mM during intense exertion and as high as 25 4328:"Standard 1.2.4 – Labelling of ingredients" 2595: 2593: 1841:The first stage in metabolizing glucose is 1775:Pyruvate is then directly used to fuel the 1400: 1399:combining form derived from the Latin word 1308:, lactate is one of the main components of 997:. It is white in the solid state and it is 854: 629:122 Β°C (252 Β°F; 395 K) at 15 4976: 4962: 4536: 4522: 4496: 4492:Lactic Acid Is Not Muscles' Foe, It's Fuel 4425: 4306:"Listing of Food Additives Status Part II" 4240:Lambic (Classic Beer Style) – Jean Guinard 2857:Journal of Diabetes Science and Technology 2158:Studies of brain slices of mice show that 1718: 1495: 509: 279: 257: 4267: 4131: 4065: 4048: 4038: 4020: 3997: 3987: 3926: 3903: 3854: 3796: 3712: 3663: 3249: 3205: 3148: 3099: 3050: 3001: 2991: 2920: 2876: 2805: 2795: 1909:), a process that absorbs these protons: 459: 445: 438: 3227: 3225: 2635: 2633: 2590: 2341:Pharmaceutical and cosmetic applications 2319:lactide polymerize to either atactic or 2177: 1993:The production of lactate from glucose ( 4445:Naushad, Mu.; Lichtfouse, Eric (2019). 3686: 3543: 3521:McArdle WD, Katch FI, Katch VL (2010). 3332:. MΓΌnchen: Hanser-Verlag. p. 103. 3251:10.1146/annurev-cancerbio-030419-033556 2718: 2716: 2714: 2381:Lactic acid is found primarily in sour 1900:and water by the Krebs cycle, in which 505: 14: 6705: 5015: 4487:Lactic Acid: Information and Resources 3477:European Journal of Applied Physiology 3327: 2658: 1696:hydroxycarboxylic acid receptor 1 1631: 1411:discovered that lactic acid (actually 270: 6215: 4957: 4517: 4133:10.1046/j.1523-1755.2001.0600031097.x 3222: 2822: 2630: 2475:fruit, making up 2.12% of the juice. 2062:and water for the production of ATP. 1353:. It is most commonly used for fluid 1173:-lactate is constantly produced from 537:Key: JVTAAEKCZFNVCJ-REOHCLBHSA-N 237: 217: 4181:this USDA database entry for yoghurt 3300: 2711: 2511: 2297: 1772:cells, heart cells, and brain cells 1677: 1296:they produce is responsible for the 844: 619:18 Β°C (64 Β°F; 291 K) 4224:"Brewing With Lactic Acid Bacteria" 2478: 2204:(even if it is more difficult than 393: 377: 370: 363: 24: 4194:Greenfield H, Southgate D (2003). 4079:Blood Test Results – Normal Ranges 4023:"Lactate fuels the neonatal brain" 3602:Trends in Pharmacological Sciences 2949:"Hydroxycarboxylic acid receptors" 1212: 51: 42: 25: 6749: 4983: 4468: 4308:. US Food and Drug Administration 2376: 1242:hydroxycarboxylic acid receptor 1 4497:Fitzgerald M (26 January 2010). 3798:10.1111/j.1471-4159.2009.06506.x 3440:Advanced Synthesis and Catalysis 3264: 3080:Journal of Clinical Microbiology 3043:10.1111/j.1399-302X.2008.00477.x 3031:Oral Microbiology and Immunology 2953:IUPHAR/BPS Guide to Pharmacology 2345:Lactic acid is also employed in 2183:Reference ranges for blood tests 2173: 1464:, or by chemical synthesis from 1219:at rest, but can rise to over 20 941: 887: 585: 4438: 4426:Druckerman P (2 October 2016). 4419: 4393: 4367: 4320: 4298: 4276: 4243: 4234: 4216: 4173: 4156: 4107: 4014: 3963: 3920: 3871: 3821: 3772: 3729: 3680: 3628: 3431: 3396: 3371: 3346: 3321: 3286: 3258: 3238:Annual Review of Cancer Biology 3165: 3116: 3067: 3018: 2967: 2659:Dawson RM, et al. (1959). 1737:is broken down and oxidized to 1729:During power exercises such as 1005:(AHA) due to the presence of a 982:. It has the molecular formula 937:(at 25 Β°C , 100 kPa). 3896:10.1523/JNEUROSCI.3355-10.2010 3847:10.1523/JNEUROSCI.3314-10.2011 3656:10.1523/JNEUROSCI.0415-11.2011 3382:. Springer-Verlag. p. 3. 2844: 2735: 2667: 2652: 2606:The Royal Society of Chemistry 2538:Category: Salts of lactic acid 2353:to adjust acidity and for its 1644:and hydrolysing the resultant 1417:-lactate) also is produced in 1342:, generally in concentrations 591: 579: 13: 1: 3415:10.1002/14356007.a15_097.pub3 3357:. Hoboken: Wiley. p. 3. 2980:The Open Microbiology Journal 2743:"(S)-lactic acid (CHEBI:422)" 2661:Data for Biochemical Research 2584: 1451: 4375:"Purac Carcass Applications" 4027:Frontiers in Neuroenergetics 3976:Frontiers in Neuroenergetics 3705:10.1113/jphysiol.2003.058701 3378:KΓΆnig H, FrΓΆhlich J (2009). 2974:Badet C, Thebaud NB (2008). 2126:Brain development metabolism 1884:+ 2 H + 2 NADH + 2 ATP + 2 H 1687:-Lactic acid is the primary 1233:-lactic acid is the primary 1198:monocarboxylate transporters 1160: 1120:lactic acid. Lactic acid is 7: 3884:The Journal of Neuroscience 3835:The Journal of Neuroscience 3644:The Journal of Neuroscience 2993:10.2174/1874285800802010038 2614:10.1039/9781849733069-00648 2531: 2066:Neural tissue energy source 1407:, meaning "milk". In 1808, 1338:in solution with distilled 38: 10: 6754: 6217: 4475:Corn Plastic to the Rescue 4286:. UK Food Standards Agency 3929:Journal of Neurophysiology 3614:10.1016/j.tips.2010.06.005 3564:10.1152/ajpregu.00114.2004 2869:10.1177/193229680700100414 2663:. Oxford: Clarendon Press. 2499: 2301: 2200:for this purpose is often 2100:lactate-shuttle hypothesis 1834:in the tissues, a form of 1747:glyceraldehyde 3-phosphate 1722: 1713:G protein-coupled receptor 1672: 1575:Streptococcus thermophilus 1560:Bacillus amyloliquefaciens 1380: 1310:lactated Ringer's solution 1259:G protein-coupled receptor 1017:industries and in various 5017: 4989: 4893: 4868: 4840: 4822: 4734: 4725: 4707: 4679: 4635: 4616: 4563: 4451:. Springer. p. 162. 3785:Journal of Neurochemistry 3693:The Journal of Physiology 3489:10.1007/s00421-017-3795-6 2689:10.1007/s10534-009-9224-5 2644:GESTIS Substance Database 2347:pharmaceutical technology 2287:fetal scalp blood testing 2254: 2229: 1995:glucose β†’ 2 lactate + 2 H 1902:oxidative phosphorylation 1534:Lactobacillus delbrueckii 1518:Lactobacillus acidophilus 1025:of lactic acid is called 931: 868: 863: 827: 715: 667: 566: 546: 521: 99: 82: 70: 65: 37: 4480:21 November 2013 at the 4040:10.3389/fnene.2011.00004 3989:10.3389/fnene.2011.00002 3687:Gladden LB (July 2004). 2371: 1945:The combined effect is: 1566:Streptococcus salivarius 1548:Lactobacillus helveticus 1543:Lactobacillus bulgaricus 1524:Lacticaseibacillus casei 1393:. The name reflects the 1357:after blood loss due to 1266:lactic acid fermentation 916:Precautionary statements 6713:Food acidity regulators 4937:Lactobacillus fermentum 4499:"The Lactic Acid Myths" 4377:. Purac. Archived from 4269:10.21273/HORTSCI.45.1.4 4084:2 November 2012 at the 3409:. Weinheim: Wiley-VCH. 2909:Pharmacological Reviews 2797:10.1073/pnas.1212976110 2570:, a lactate transporter 2543:Category:Lactate esters 2462:malolactic fermentation 2418:nutritional information 2292: 1927:+ 2 H + 2 NADH β†’ 2 CH 1862:+ 2 NAD + 2 ADP + 2 HPO 1822:physiological condition 1719:Metabolism and exercise 1501:Fermented milk products 1496:Fermentative production 1331:along with lactate and 1272:, which convert simple 761:3-Hydroxypropanoic acid 76:2-Hydroxypropanoic acid 4646:Diiodohydroxyquinoline 3452:10.1002/adsc.201600768 3330:Technische Biopolymere 3308:Chemists and Chemistry 2315:. In the presence of 2186: 1725:N-Lactoylphenylalanine 1401: 1184:(LDH) in a process of 1009:group adjacent to the 56: 47: 3941:10.1152/jn.00293.2011 3178:Clin J Am Soc Nephrol 2922:10.1124/pr.110.003301 2608:. 2014. p. 748. 2558:Biodegradable plastic 2194:acid base homeostasis 2181: 2086:species that include 1907:lactate dehydrogenase 1428:In 1856, the role of 1182:lactate dehydrogenase 55: 46: 4120:Kidney International 4021:Kasischke K (2011). 3190:10.2215/CJN.04500422 3092:10.1128/JCM.01410-07 2466:lactic acid bacteria 2098:. According to the 1594:(Pentose sugar) and 1443:Boehringer Ingelheim 1409:JΓΆns Jacob Berzelius 1387:Carl Wilhelm Scheele 1270:lactic acid bacteria 1086:, consisting of two 72:Preferred IUPAC name 6723:Exercise physiology 6718:Alpha hydroxy acids 4169:. 2015. p. 13. 3272:Scientific American 2788:2013PNAS..110.8738S 2213: 2147:, making them more 2116:cerebrospinal fluid 2108:extracellular fluid 1768:by well-oxygenated 1632:Chemical production 1610:Lactobacillus casei 1529:Lactobacillus casei 1423:Johannes Wislicenus 1314:Hartmann's solution 1204:lactate is usually 1164:, meaning "flesh". 776:Hydroxybutyric acid 640:Solubility in water 609: gΒ·mol 199:Beilstein Reference 34: 6738:E-number additives 4509:on 25 August 2018. 4503:Competitor Running 4432:The New York Times 3750:10.1002/glia.20528 3328:Endres HJ (2009). 2385:products, such as 2211: 2187: 1836:metabolic acidosis 1614:Lactococcus lactis 1554:Lactococcus lactis 1320:fluids consist of 1217:Tooltip millimolar 1090:. One is known as 1003:alpha-hydroxy acid 964:Infobox references 716:Related compounds 57: 48: 32: 6700: 6699: 6694: 6693: 4951: 4950: 4889: 4888: 4458:978-3-030-11345-2 3536:978-0-683-05731-7 3446:(24): 3910–3931. 3389:978-3-540-85462-3 3364:978-0-470-29366-9 3355:Poly(Lactic acid) 3339:978-3-446-41683-3 3141:10.1159/000096099 2830:"Lactate Profile" 2723:Sigma-Aldrich Co. 2623:978-0-85404-182-4 2526:calcium carbonate 2524:deposits such as 2512:Cleaning products 2464:is undertaken by 2451:American wild ale 2326:(PLA), which are 2298:Polymer precursor 2279: 2278: 2212:Reference ranges 2160:Ξ²-hydroxybutyrate 2155:levels, or both. 1678:Molecular biology 1658:ammonium chloride 1654:hydrochloric acid 1140:-Lactic acid and 1116:-lactic acid, or 1015:organic synthesis 972:Chemical compound 970: 969: 898:Hazard statements 786:Related compounds 490:CompTox Dashboard 169:Interactive image 61: 60: 16:(Redirected from 6745: 6669: 6647: 6625: 6604: 6582: 6560: 6538: 6511: 6489: 6467: 6445: 6423: 6401: 6379: 6357: 6335: 6310: 6288: 6266: 6244: 6159: 6123: 6101: 6083: 6062: 6034: 6002: 5980: 5955: 5933: 5905: 5883: 5861: 5839: 5821: 5799: 5777: 5755: 5733: 5712: 5691: 5669: 5647: 5625: 5601: 5579: 5548: 5526: 5504: 5483: 5465: 5443: 5421: 5400: 5378: 5356: 5335: 5313: 5292: 5270: 5251: 5227: 5205: 5174: 5152: 5130: 5105: 5087: 5061: 5039: 5010: 4993: 4992: 4978: 4971: 4964: 4955: 4954: 4881:Methylrosaniline 4732: 4731: 4538: 4531: 4524: 4515: 4514: 4510: 4505:. Archived from 4463: 4462: 4442: 4436: 4435: 4423: 4417: 4416: 4414: 4412: 4397: 4391: 4390: 4388: 4386: 4371: 4365: 4364: 4362: 4360: 4349: 4340: 4339: 4337: 4335: 4324: 4318: 4317: 4315: 4313: 4302: 4296: 4295: 4293: 4291: 4280: 4274: 4273: 4271: 4247: 4241: 4238: 4232: 4231: 4220: 4214: 4213: 4191: 4185: 4179:For example, in 4177: 4171: 4170: 4168: 4160: 4154: 4153: 4135: 4126:(3): 1097–1105. 4111: 4105: 4102: 4089: 4076: 4063: 4062: 4052: 4042: 4018: 4012: 4011: 4001: 3991: 3967: 3961: 3960: 3924: 3918: 3917: 3907: 3890:(46): 15638–42. 3875: 3869: 3868: 3858: 3825: 3819: 3818: 3800: 3776: 3770: 3769: 3733: 3727: 3726: 3716: 3684: 3678: 3677: 3667: 3641: 3632: 3626: 3625: 3597: 3584: 3583: 3558:(3): R502–R516. 3547: 3541: 3540: 3528: 3518: 3509: 3508: 3471: 3456: 3455: 3435: 3429: 3428: 3400: 3394: 3393: 3375: 3369: 3368: 3350: 3344: 3343: 3325: 3319: 3304: 3298: 3297: 3290: 3284: 3283: 3281: 3279: 3262: 3256: 3255: 3253: 3229: 3220: 3219: 3209: 3169: 3163: 3162: 3152: 3120: 3114: 3113: 3103: 3071: 3065: 3064: 3054: 3022: 3016: 3015: 3005: 2995: 2971: 2965: 2964: 2962: 2960: 2944: 2935: 2934: 2924: 2900: 2891: 2890: 2880: 2848: 2842: 2841: 2839: 2837: 2826: 2820: 2819: 2809: 2799: 2767: 2758: 2757: 2755: 2753: 2739: 2733: 2729: 2720: 2709: 2708: 2671: 2665: 2664: 2656: 2650: 2637: 2628: 2627: 2597: 2579:Methacrylic acid 2479:Separately added 2214: 2210: 2145:developing brain 2143:networks in the 2061: 2051: 2049: 2048: 2045: 2016: 2014: 2013: 2010: 1996: 1989: 1983: 1982: 1979: 1970: 1969: 1966: 1941: 1939: 1938: 1935: 1926: 1925: 1922: 1899: 1889: 1883: 1882: 1879: 1870: 1869: 1866: 1829: 1828: 1711: 1686: 1685: 1652:is performed by 1642:hydrogen cyanide 1607: 1605: 1604: 1593: 1591: 1590: 1491: 1490: 1485: 1484: 1479: 1478: 1473: 1472: 1416: 1415: 1406: 1385:Swedish chemist 1268:is performed by 1257: 1232: 1231: 1226: 1222: 1218: 1214: 1210: 1207: 1172: 1171: 1163: 1157: 1156: 1151: 1150: 1145: 1144: 1139: 1138: 1130:-Lactic acid is 1129: 1128: 1115: 1114: 1105: 1104: 1095: 1094: 1063: 1062: 1061: 1053: 1052: 1021:industries. The 954: 948: 945: 944: 927: 923: 909: 905: 891: 858: 848: 737:carboxylic acids 710: 706: 702: 698: 691: 668:Thermochemistry 632: 608: 593: 587: 581: 574:Chemical formula 514: 513: 498: 496: 469: 468: 463: 455: 454: 449: 442: 406: 395: 381: 374: 367: 347: 323:Gmelin Reference 309: 291: 283: 272: 261: 241: 221: 189: 171: 146: 145: 140: 132: 131: 126: 119: 39: 35: 31: 21: 6753: 6752: 6748: 6747: 6746: 6744: 6743: 6742: 6733:Propionic acids 6703: 6702: 6701: 6696: 6695: 6668: 6664: 6660: 6656: 6652: 6646: 6642: 6638: 6634: 6630: 6624: 6620: 6616: 6612: 6608: 6606: 6603: 6599: 6595: 6591: 6587: 6581: 6577: 6573: 6569: 6565: 6559: 6555: 6551: 6547: 6543: 6537: 6533: 6529: 6525: 6521: 6510: 6506: 6502: 6498: 6494: 6488: 6484: 6480: 6476: 6472: 6466: 6462: 6458: 6454: 6450: 6444: 6440: 6436: 6432: 6428: 6422: 6418: 6414: 6410: 6406: 6400: 6396: 6392: 6388: 6384: 6378: 6374: 6370: 6366: 6362: 6356: 6352: 6348: 6344: 6340: 6334: 6330: 6326: 6322: 6318: 6309: 6305: 6301: 6297: 6293: 6287: 6283: 6279: 6275: 6271: 6265: 6261: 6257: 6253: 6249: 6243: 6239: 6235: 6231: 6227: 6158: 6154: 6150: 6146: 6142: 6122: 6118: 6114: 6110: 6106: 6100: 6096: 6092: 6088: 6082: 6078: 6074: 6070: 6066: 6064: 6061: 6057: 6053: 6049: 6045: 6041: 6033: 6029: 6025: 6021: 6017: 6001: 5997: 5993: 5989: 5985: 5979: 5975: 5971: 5967: 5963: 5954: 5950: 5946: 5942: 5938: 5932: 5928: 5924: 5920: 5904: 5900: 5896: 5892: 5888: 5882: 5878: 5874: 5870: 5866: 5860: 5856: 5852: 5848: 5844: 5838: 5834: 5830: 5826: 5820: 5816: 5812: 5808: 5804: 5798: 5794: 5790: 5786: 5782: 5776: 5772: 5768: 5764: 5760: 5754: 5750: 5746: 5742: 5738: 5732: 5728: 5724: 5720: 5716: 5714: 5711: 5707: 5703: 5699: 5695: 5693: 5690: 5686: 5682: 5678: 5674: 5668: 5664: 5660: 5656: 5652: 5646: 5642: 5638: 5634: 5630: 5624: 5620: 5616: 5612: 5608: 5600: 5596: 5592: 5588: 5584: 5578: 5574: 5570: 5566: 5547: 5543: 5539: 5535: 5531: 5525: 5521: 5517: 5513: 5509: 5503: 5499: 5495: 5491: 5487: 5485: 5482: 5478: 5474: 5470: 5464: 5460: 5456: 5452: 5448: 5442: 5438: 5434: 5430: 5426: 5420: 5416: 5412: 5408: 5404: 5402: 5399: 5395: 5391: 5387: 5383: 5377: 5373: 5369: 5365: 5361: 5355: 5351: 5347: 5343: 5339: 5337: 5334: 5330: 5326: 5322: 5318: 5312: 5308: 5304: 5300: 5296: 5294: 5291: 5287: 5283: 5279: 5275: 5268: 5264: 5260: 5256: 5250: 5246: 5242: 5238: 5234: 5226: 5222: 5218: 5214: 5210: 5204: 5200: 5196: 5192: 5173: 5169: 5165: 5161: 5157: 5151: 5147: 5143: 5139: 5135: 5129: 5125: 5121: 5117: 5104: 5100: 5096: 5092: 5086: 5082: 5078: 5074: 5070: 5060: 5056: 5052: 5048: 5044: 5038: 5034: 5030: 5026: 5009: 5005: 5001: 4997: 4985: 4982: 4952: 4947: 4926:Povidone-iodine 4885: 4864: 4836: 4818: 4721: 4703: 4675: 4631: 4612: 4588:Oxytetracycline 4578:Chloramphenicol 4559: 4548:anti-infectives 4542: 4482:Wayback Machine 4471: 4466: 4459: 4443: 4439: 4424: 4420: 4410: 4408: 4399: 4398: 4394: 4384: 4382: 4381:on 29 July 2013 4373: 4372: 4368: 4358: 4356: 4351: 4350: 4343: 4333: 4331: 4326: 4325: 4321: 4311: 4309: 4304: 4303: 4299: 4289: 4287: 4282: 4281: 4277: 4248: 4244: 4239: 4235: 4222: 4221: 4217: 4210: 4202:. p. 146. 4192: 4188: 4178: 4174: 4166: 4162: 4161: 4157: 4112: 4108: 4103: 4092: 4086:Wayback Machine 4077: 4066: 4019: 4015: 3968: 3964: 3925: 3921: 3876: 3872: 3826: 3822: 3777: 3773: 3744:(12): 1251–62. 3734: 3730: 3685: 3681: 3650:(20): 7477–85. 3639: 3633: 3629: 3598: 3587: 3548: 3544: 3537: 3519: 3512: 3472: 3459: 3436: 3432: 3425: 3401: 3397: 3390: 3376: 3372: 3365: 3351: 3347: 3340: 3326: 3322: 3318:, 9780792306252 3305: 3301: 3292: 3291: 3287: 3277: 3275: 3263: 3259: 3230: 3223: 3170: 3166: 3129:Caries Research 3121: 3117: 3072: 3068: 3023: 3019: 2972: 2968: 2958: 2956: 2945: 2938: 2901: 2894: 2849: 2845: 2835: 2833: 2828: 2827: 2823: 2782:(21): 8738–43. 2768: 2761: 2751: 2749: 2741: 2740: 2736: 2727: 2721: 2712: 2672: 2668: 2657: 2653: 2638: 2631: 2624: 2599: 2598: 2591: 2587: 2574:Thiolactic acid 2534: 2518:descaling agent 2514: 2502: 2481: 2443:Berliner weisse 2403:cottage cheeses 2379: 2374: 2343: 2306: 2304:polylactic acid 2300: 2295: 2176: 2128: 2068: 2060: 2056: 2046: 2043: 2042: 2040: 2036: 2032: 2028: 2024: 2011: 2008: 2007: 2005: 2001: 1994: 1987: 1980: 1977: 1976: 1974: 1967: 1964: 1963: 1961: 1957: 1953: 1949: 1936: 1933: 1932: 1930: 1923: 1920: 1919: 1917: 1913: 1898: 1894: 1887: 1880: 1877: 1876: 1874: 1867: 1864: 1863: 1861: 1857: 1853: 1849: 1826: 1825: 1818:Lactic acidosis 1810:red blood cells 1789:gluconeogenesis 1727: 1721: 1708: 1703: 1701: 1683: 1682: 1680: 1675: 1634: 1603: 1600: 1599: 1598: 1595: 1589: 1586: 1585: 1584: 1581: 1498: 1488: 1487: 1482: 1481: 1476: 1475: 1470: 1469: 1454: 1413: 1412: 1383: 1300:decay known as 1254: 1249: 1247: 1229: 1228: 1224: 1220: 1216: 1208: 1205: 1169: 1168: 1154: 1153: 1148: 1147: 1142: 1141: 1136: 1135: 1126: 1125: 1112: 1111: 1106:-lactic acid, ( 1102: 1101: 1096:-lactic acid, ( 1092: 1091: 1082:Lactic acid is 1076: 1060: 1057: 1056: 1055: 1051: 1048: 1047: 1046: 1044: 995: 991: 987: 973: 966: 961: 960: 959:  ?) 950: 946: 942: 938: 918: 900: 884: 837: 823: 804:Propionaldehyde 787: 780: 739: 726: 708: 704: 700: 696: 692: 689: 683: 679: 676: 675:Std enthalpy of 659: 642: 630: 606: 596: 590: 584: 576: 562: 559: 554: 553: 542: 539: 538: 535: 529: 528: 517: 499: 492: 473: 466: 465: 452: 451: 425: 409: 396: 384: 350: 337: 325: 315:(preservatives) 301: 264: 244: 224: 201: 192: 174: 161: 150: 143: 142: 129: 128: 109: 95: 94: 78: 77: 28: 23: 22: 15: 12: 11: 5: 6751: 6741: 6740: 6735: 6730: 6725: 6720: 6715: 6698: 6697: 6692: 6691: 6688: 6685: 6682: 6680: 6678: 6675: 6673: 6671: 6666: 6662: 6658: 6654: 6649: 6644: 6640: 6636: 6632: 6627: 6622: 6618: 6614: 6610: 6601: 6597: 6593: 6589: 6584: 6579: 6575: 6571: 6567: 6562: 6557: 6553: 6549: 6545: 6540: 6535: 6531: 6527: 6523: 6518: 6514: 6513: 6508: 6504: 6500: 6496: 6491: 6486: 6482: 6478: 6474: 6469: 6464: 6460: 6456: 6452: 6447: 6442: 6438: 6434: 6430: 6425: 6420: 6416: 6412: 6408: 6403: 6398: 6394: 6390: 6386: 6381: 6376: 6372: 6368: 6364: 6359: 6354: 6350: 6346: 6342: 6337: 6332: 6328: 6324: 6320: 6315: 6312: 6307: 6303: 6299: 6295: 6290: 6285: 6281: 6277: 6273: 6268: 6263: 6259: 6255: 6251: 6246: 6241: 6237: 6233: 6229: 6224: 6220: 6219: 6216: 6213: 6212: 6209: 6206: 6203: 6200: 6197: 6194: 6191: 6188: 6185: 6182: 6179: 6176: 6173: 6170: 6167: 6164: 6161: 6156: 6152: 6148: 6144: 6139: 6135: 6134: 6131: 6129: 6127: 6125: 6120: 6116: 6112: 6108: 6103: 6098: 6094: 6090: 6085: 6080: 6076: 6072: 6068: 6059: 6055: 6051: 6047: 6043: 6038: 6036: 6031: 6027: 6023: 6019: 6014: 6012: 6010: 6008: 6006: 6004: 5999: 5995: 5991: 5987: 5982: 5977: 5973: 5969: 5965: 5960: 5957: 5952: 5948: 5944: 5940: 5935: 5930: 5926: 5922: 5916: 5915: 5913: 5911: 5909: 5907: 5902: 5898: 5894: 5890: 5885: 5880: 5876: 5872: 5868: 5863: 5858: 5854: 5850: 5846: 5841: 5836: 5832: 5828: 5823: 5818: 5814: 5810: 5806: 5801: 5796: 5792: 5788: 5784: 5779: 5774: 5770: 5766: 5762: 5757: 5752: 5748: 5744: 5740: 5735: 5730: 5726: 5722: 5718: 5709: 5705: 5701: 5697: 5688: 5684: 5680: 5676: 5671: 5666: 5662: 5658: 5654: 5649: 5644: 5640: 5636: 5632: 5627: 5622: 5618: 5614: 5610: 5605: 5603: 5598: 5594: 5590: 5586: 5581: 5576: 5572: 5568: 5562: 5561: 5558: 5556: 5554: 5552: 5550: 5545: 5541: 5537: 5533: 5528: 5523: 5519: 5515: 5511: 5506: 5501: 5497: 5493: 5489: 5480: 5476: 5472: 5467: 5462: 5458: 5454: 5450: 5445: 5440: 5436: 5432: 5428: 5423: 5418: 5414: 5410: 5406: 5397: 5393: 5389: 5385: 5380: 5375: 5371: 5367: 5363: 5358: 5353: 5349: 5345: 5341: 5332: 5328: 5324: 5320: 5315: 5310: 5306: 5302: 5298: 5289: 5285: 5281: 5277: 5272: 5266: 5262: 5258: 5253: 5248: 5244: 5240: 5236: 5231: 5229: 5224: 5220: 5216: 5212: 5207: 5202: 5198: 5194: 5188: 5187: 5184: 5182: 5180: 5178: 5176: 5171: 5167: 5163: 5159: 5154: 5149: 5145: 5141: 5137: 5132: 5127: 5123: 5119: 5113: 5112: 5109: 5107: 5102: 5098: 5094: 5089: 5084: 5080: 5076: 5072: 5067: 5065: 5063: 5058: 5054: 5050: 5046: 5041: 5036: 5032: 5028: 5022: 5021: 5018: 5016: 5014: 5012: 5007: 5003: 4999: 4991: 4990: 4987: 4986: 4981: 4980: 4973: 4966: 4958: 4949: 4948: 4946: 4945: 4940: 4933: 4928: 4923: 4918: 4913: 4908: 4903: 4897: 4895: 4891: 4890: 4887: 4886: 4884: 4883: 4878: 4872: 4870: 4866: 4865: 4863: 4862: 4860:Amphotericin B 4857: 4852: 4846: 4844: 4838: 4837: 4835: 4834: 4828: 4826: 4820: 4819: 4817: 4816: 4811: 4806: 4801: 4796: 4791: 4786: 4781: 4776: 4771: 4766: 4761: 4756: 4751: 4746: 4740: 4738: 4729: 4723: 4722: 4720: 4719: 4713: 4711: 4705: 4704: 4702: 4701: 4696: 4691: 4685: 4683: 4677: 4676: 4674: 4673: 4668: 4666:Broxyquinoline 4663: 4658: 4656:Chlorquinaldol 4653: 4648: 4642: 4640: 4633: 4632: 4630: 4629: 4623: 4621: 4614: 4613: 4611: 4610: 4605: 4600: 4595: 4590: 4585: 4580: 4575: 4569: 4567: 4561: 4560: 4541: 4540: 4533: 4526: 4518: 4512: 4511: 4494: 4489: 4484: 4470: 4469:External links 4467: 4465: 4464: 4457: 4437: 4418: 4392: 4366: 4341: 4319: 4297: 4275: 4242: 4233: 4215: 4208: 4186: 4172: 4155: 4106: 4090: 4064: 4013: 3962: 3919: 3870: 3820: 3771: 3728: 3699:(Pt 1): 5–30. 3679: 3627: 3608:(9): 394–401. 3585: 3542: 3535: 3510: 3483:(4): 691–728. 3457: 3430: 3423: 3395: 3388: 3370: 3363: 3345: 3338: 3320: 3299: 3285: 3257: 3221: 3184:(1): 102–112. 3164: 3115: 3086:(4): 1407–17. 3066: 3017: 2966: 2936: 2892: 2843: 2821: 2759: 2734: 2710: 2666: 2651: 2629: 2622: 2588: 2586: 2583: 2582: 2581: 2576: 2571: 2565: 2560: 2555: 2550: 2545: 2540: 2533: 2530: 2513: 2510: 2501: 2498: 2480: 2477: 2378: 2377:Fermented food 2375: 2373: 2370: 2342: 2339: 2335:petrochemicals 2302:Main article: 2299: 2296: 2294: 2291: 2277: 2276: 2273: 2270: 2266: 2265: 2262: 2259: 2256: 2252: 2251: 2248: 2245: 2241: 2240: 2237: 2234: 2231: 2227: 2226: 2223: 2220: 2217: 2198:Blood sampling 2175: 2172: 2127: 2124: 2067: 2064: 2058: 2053: 2052: 2038: 2034: 2030: 2026: 2018: 2017: 2003: 1991: 1990: 1985: 1972: 1962:+ 2 ADP + 2HPO 1959: 1955: 1951: 1943: 1942: 1928: 1915: 1896: 1891: 1890: 1885: 1872: 1859: 1855: 1851: 1805: 1804: 1803: 1802: 1783:Conversion to 1781: 1780: 1779: 1720: 1717: 1706: 1699: 1679: 1676: 1674: 1671: 1633: 1630: 1618:carbon dioxide 1601: 1587: 1497: 1494: 1453: 1450: 1382: 1379: 1252: 1248:), which is a 1245: 1188:during normal 1074: 1064:. Compared to 1058: 1049: 1023:conjugate base 993: 989: 985: 971: 968: 967: 962: 940: 939: 935:standard state 932: 929: 928: 926:P305+P351+P338 919: 914: 911: 910: 901: 896: 893: 892: 885: 880: 877: 876: 866: 865: 861: 860: 838: 833: 830: 829: 825: 824: 822: 821: 816: 814:Sodium lactate 811: 806: 801: 796: 790: 788: 785: 782: 781: 779: 778: 773: 768: 763: 758: 756:Propionic acid 753: 748: 742: 740: 734: 731: 730: 727: 721: 718: 717: 713: 712: 703:kcal/mol, 15.1 693: 687: 681: 673: 670: 669: 665: 664: 661: 657: 647: 646: 643: 638: 635: 634: 627: 621: 620: 617: 611: 610: 604: 598: 597: 594: 588: 582: 577: 572: 569: 568: 564: 563: 561: 560: 557: 549: 548: 547: 544: 543: 541: 540: 536: 533: 532: 524: 523: 522: 519: 518: 516: 515: 502: 500: 488: 485: 484: 481: 475: 474: 472: 471: 457: 443: 435: 433: 427: 426: 424: 423: 419: 417: 411: 410: 408: 407: 399: 397: 389: 386: 385: 383: 382: 375: 368: 360: 358: 352: 351: 349: 348: 340: 338: 333: 330: 329: 326: 321: 318: 317: 311: 303: 302: 300: 299: 295: 293: 285: 284: 274: 266: 265: 263: 262: 254: 252: 246: 245: 243: 242: 234: 232: 226: 225: 223: 222: 214: 212: 206: 205: 202: 197: 194: 193: 191: 190: 182: 180: 176: 175: 173: 172: 164: 162: 155: 152: 151: 149: 148: 134: 120: 112: 110: 105: 102: 101: 97: 96: 93: 92: 89: 85: 84: 80: 79: 75: 74: 68: 67: 63: 62: 59: 58: 49: 26: 9: 6: 4: 3: 2: 6750: 6739: 6736: 6734: 6731: 6729: 6728:Preservatives 6726: 6724: 6721: 6719: 6716: 6714: 6711: 6710: 6708: 6689: 6686: 6683: 6681: 6679: 6676: 6674: 6672: 6670: 6650: 6648: 6628: 6626: 6605: 6585: 6583: 6563: 6561: 6541: 6539: 6519: 6516: 6515: 6512: 6492: 6490: 6470: 6468: 6448: 6446: 6426: 6424: 6404: 6402: 6382: 6380: 6360: 6358: 6338: 6336: 6316: 6313: 6311: 6291: 6289: 6269: 6267: 6247: 6245: 6225: 6222: 6221: 6214: 6210: 6207: 6204: 6201: 6198: 6195: 6192: 6189: 6186: 6183: 6180: 6177: 6174: 6171: 6168: 6165: 6162: 6160: 6140: 6137: 6136: 6132: 6130: 6128: 6126: 6124: 6104: 6102: 6086: 6084: 6063: 6039: 6037: 6035: 6015: 6013: 6011: 6009: 6007: 6005: 6003: 5983: 5981: 5961: 5958: 5956: 5936: 5934: 5918: 5917: 5914: 5912: 5910: 5908: 5906: 5886: 5884: 5864: 5862: 5842: 5840: 5824: 5822: 5802: 5800: 5780: 5778: 5758: 5756: 5736: 5734: 5713: 5692: 5672: 5670: 5650: 5648: 5628: 5626: 5606: 5604: 5602: 5582: 5580: 5564: 5563: 5559: 5557: 5555: 5553: 5551: 5549: 5529: 5527: 5507: 5505: 5484: 5468: 5466: 5446: 5444: 5424: 5422: 5401: 5381: 5379: 5359: 5357: 5336: 5316: 5314: 5293: 5273: 5271: 5254: 5252: 5232: 5230: 5228: 5208: 5206: 5190: 5189: 5185: 5183: 5181: 5179: 5177: 5175: 5155: 5153: 5133: 5131: 5115: 5114: 5110: 5108: 5106: 5090: 5088: 5068: 5066: 5064: 5062: 5042: 5040: 5024: 5023: 5019: 5013: 5011: 4995: 4994: 4988: 4984:Lactate salts 4979: 4974: 4972: 4967: 4965: 4960: 4959: 4956: 4944: 4943:Copper usnate 4941: 4939: 4938: 4934: 4932: 4929: 4927: 4924: 4922: 4919: 4917: 4914: 4912: 4909: 4907: 4904: 4902: 4899: 4898: 4896: 4892: 4882: 4879: 4877: 4874: 4873: 4871: 4867: 4861: 4858: 4856: 4853: 4851: 4848: 4847: 4845: 4843: 4839: 4833: 4830: 4829: 4827: 4825: 4821: 4815: 4812: 4810: 4807: 4805: 4802: 4800: 4797: 4795: 4794:Propenidazole 4792: 4790: 4787: 4785: 4784:Fenticonazole 4782: 4780: 4777: 4775: 4772: 4770: 4767: 4765: 4762: 4760: 4757: 4755: 4752: 4750: 4747: 4745: 4744:Metronidazole 4742: 4741: 4739: 4737: 4733: 4730: 4728: 4724: 4718: 4717:Sulfatolamide 4715: 4714: 4712: 4710: 4706: 4700: 4699:Ascorbic acid 4697: 4695: 4692: 4690: 4687: 4686: 4684: 4682: 4681:Organic acids 4678: 4672: 4669: 4667: 4664: 4662: 4659: 4657: 4654: 4652: 4649: 4647: 4644: 4643: 4641: 4638: 4634: 4628: 4625: 4624: 4622: 4619: 4615: 4609: 4606: 4604: 4601: 4599: 4596: 4594: 4591: 4589: 4586: 4584: 4581: 4579: 4576: 4574: 4571: 4570: 4568: 4566: 4562: 4557: 4553: 4549: 4546: 4545:Gynecological 4539: 4534: 4532: 4527: 4525: 4520: 4519: 4516: 4508: 4504: 4500: 4495: 4493: 4490: 4488: 4485: 4483: 4479: 4476: 4473: 4472: 4460: 4454: 4450: 4449: 4441: 4433: 4429: 4422: 4406: 4402: 4396: 4380: 4376: 4370: 4354: 4348: 4346: 4329: 4323: 4307: 4301: 4285: 4279: 4270: 4265: 4261: 4257: 4253: 4246: 4237: 4229: 4225: 4219: 4211: 4209:9789251049495 4205: 4201: 4197: 4190: 4182: 4176: 4165: 4159: 4151: 4147: 4143: 4139: 4134: 4129: 4125: 4121: 4117: 4110: 4101: 4099: 4097: 4095: 4088:Bloodbook.Com 4087: 4083: 4080: 4075: 4073: 4071: 4069: 4060: 4056: 4051: 4046: 4041: 4036: 4032: 4028: 4024: 4017: 4009: 4005: 4000: 3995: 3990: 3985: 3981: 3977: 3973: 3966: 3958: 3954: 3950: 3946: 3942: 3938: 3935:(3): 1065–7. 3934: 3930: 3923: 3915: 3911: 3906: 3901: 3897: 3893: 3889: 3885: 3881: 3874: 3866: 3862: 3857: 3852: 3848: 3844: 3840: 3836: 3832: 3824: 3816: 3812: 3808: 3804: 3799: 3794: 3791:(4): 900–12. 3790: 3786: 3782: 3775: 3767: 3763: 3759: 3755: 3751: 3747: 3743: 3739: 3732: 3724: 3720: 3715: 3710: 3706: 3702: 3698: 3694: 3690: 3683: 3675: 3671: 3666: 3661: 3657: 3653: 3649: 3645: 3638: 3631: 3623: 3619: 3615: 3611: 3607: 3603: 3596: 3594: 3592: 3590: 3581: 3577: 3573: 3569: 3565: 3561: 3557: 3553: 3546: 3538: 3532: 3527: 3526: 3517: 3515: 3506: 3502: 3498: 3494: 3490: 3486: 3482: 3478: 3470: 3468: 3466: 3464: 3462: 3453: 3449: 3445: 3441: 3434: 3426: 3424:9783527306732 3420: 3416: 3412: 3408: 3407: 3399: 3391: 3385: 3381: 3374: 3366: 3360: 3356: 3349: 3341: 3335: 3331: 3324: 3317: 3313: 3310:. Springer, 3309: 3303: 3295: 3289: 3274: 3273: 3268: 3261: 3252: 3247: 3243: 3239: 3235: 3228: 3226: 3217: 3213: 3208: 3203: 3199: 3195: 3191: 3187: 3183: 3179: 3175: 3168: 3160: 3156: 3151: 3146: 3142: 3138: 3134: 3130: 3126: 3119: 3111: 3107: 3102: 3097: 3093: 3089: 3085: 3081: 3077: 3070: 3062: 3058: 3053: 3048: 3044: 3040: 3036: 3032: 3028: 3021: 3013: 3009: 3004: 2999: 2994: 2989: 2985: 2981: 2977: 2970: 2954: 2950: 2943: 2941: 2932: 2928: 2923: 2918: 2915:(2): 269–90. 2914: 2910: 2906: 2899: 2897: 2888: 2884: 2879: 2874: 2870: 2866: 2863:(4): 558–69. 2862: 2858: 2854: 2847: 2831: 2825: 2817: 2813: 2808: 2803: 2798: 2793: 2789: 2785: 2781: 2777: 2773: 2766: 2764: 2748: 2747:www.ebi.ac.uk 2744: 2738: 2731: 2724: 2719: 2717: 2715: 2706: 2702: 2698: 2694: 2690: 2686: 2682: 2678: 2670: 2662: 2655: 2649: 2645: 2641: 2636: 2634: 2625: 2619: 2615: 2611: 2607: 2604:. Cambridge: 2603: 2596: 2594: 2589: 2580: 2577: 2575: 2572: 2569: 2566: 2564: 2563:Dental caries 2561: 2559: 2556: 2554: 2553:Alanine cycle 2551: 2549: 2548:Acids in wine 2546: 2544: 2541: 2539: 2536: 2535: 2529: 2527: 2523: 2520:for removing 2519: 2509: 2507: 2497: 2494: 2490: 2486: 2485:food additive 2476: 2474: 2469: 2467: 2463: 2459: 2454: 2452: 2448: 2444: 2440: 2436: 2432: 2427: 2424: 2419: 2414: 2412: 2408: 2404: 2400: 2396: 2392: 2388: 2384: 2369: 2367: 2362: 2360: 2356: 2352: 2348: 2338: 2336: 2332: 2329: 2328:biodegradable 2325: 2322: 2318: 2314: 2311: 2305: 2290: 2288: 2284: 2274: 2271: 2268: 2267: 2263: 2260: 2257: 2253: 2249: 2246: 2243: 2242: 2238: 2235: 2232: 2228: 2224: 2221: 2218: 2216: 2215: 2209: 2207: 2203: 2199: 2196:in the body. 2195: 2191: 2184: 2180: 2174:Blood testing 2171: 2167: 2165: 2161: 2156: 2154: 2150: 2146: 2142: 2137: 2133: 2123: 2121: 2120:microdialysis 2117: 2113: 2109: 2105: 2101: 2097: 2093: 2089: 2085: 2081: 2077: 2073: 2063: 2023: 2022: 2021: 2006:O β†’ ADP + HPO 2000: 1999: 1998: 1984:+ 2 ATP + 2 H 1948: 1947: 1946: 1912: 1911: 1910: 1908: 1903: 1848: 1847: 1846: 1844: 1839: 1837: 1833: 1823: 1819: 1815: 1812:, which lack 1811: 1800: 1796: 1795: 1794: 1790: 1786: 1782: 1778: 1774: 1773: 1771: 1767: 1763: 1760: 1759: 1758: 1755: 1754:to continue. 1753: 1748: 1744: 1740: 1736: 1732: 1726: 1716: 1714: 1710: 1697: 1693: 1690: 1670: 1668: 1664: 1663:vinyl acetate 1659: 1655: 1651: 1647: 1643: 1639: 1629: 1627: 1623: 1619: 1615: 1611: 1606: 1592: 1578: 1576: 1572: 1571: 1567: 1562: 1561: 1556: 1555: 1550: 1549: 1544: 1540: 1539: 1535: 1530: 1526: 1525: 1520: 1519: 1514: 1513:Lactobacillus 1510: 1506: 1502: 1493: 1467: 1463: 1462:carbohydrates 1459: 1449: 1446: 1444: 1441: 1437: 1436:Louis Pasteur 1433: 1432: 1431:Lactobacillus 1426: 1424: 1420: 1410: 1405: 1404: 1398: 1397: 1392: 1388: 1378: 1375: 1370: 1368: 1364: 1360: 1356: 1355:resuscitation 1352: 1349: 1345: 1341: 1337: 1334: 1330: 1327: 1323: 1319: 1315: 1311: 1307: 1303: 1299: 1295: 1291: 1287: 1283: 1279: 1275: 1274:carbohydrates 1271: 1267: 1264:In industry, 1262: 1260: 1256: 1243: 1239: 1236: 1215: 1203: 1199: 1195: 1191: 1187: 1183: 1180: 1176: 1165: 1162: 1133: 1123: 1119: 1109: 1099: 1089: 1085: 1080: 1077: 1073: 1067: 1043: 1038: 1036: 1032: 1028: 1024: 1020: 1016: 1012: 1008: 1004: 1000: 996: 981: 977: 965: 958: 953: 936: 930: 920: 917: 913: 912: 902: 899: 895: 894: 890: 886: 883: 879: 878: 874: 872: 867: 862: 857: 852: 847: 842: 839: 836: 832: 831: 828:Pharmacology 826: 820: 819:Ethyl lactate 817: 815: 812: 810: 807: 805: 802: 800: 797: 795: 792: 791: 789: 784: 783: 777: 774: 772: 769: 767: 764: 762: 759: 757: 754: 752: 751:Glycolic acid 749: 747: 744: 743: 741: 738: 733: 732: 728: 725: 720: 719: 714: 699:kJ/mol, 325.5 694: 686: 678: 672: 671: 666: 662: 656: 652: 649: 648: 644: 641: 637: 636: 628: 626: 625:Boiling point 623: 622: 618: 616: 615:Melting point 613: 612: 605: 603: 600: 599: 578: 575: 571: 570: 565: 556: 555: 552: 545: 531: 530: 527: 520: 512: 508: 507:DTXSID7023192 504: 503: 501: 491: 487: 486: 482: 480: 477: 476: 462: 458: 448: 444: 441: 437: 436: 434: 432: 429: 428: 421: 420: 418: 416: 413: 412: 405: 401: 400: 398: 392: 388: 387: 380: 376: 373: 369: 366: 362: 361: 359: 357: 354: 353: 346: 342: 341: 339: 336: 332: 331: 327: 324: 320: 319: 316: 312: 310: 305: 304: 297: 296: 294: 292: 287: 286: 282: 278: 275: 273: 271:ECHA InfoCard 268: 267: 260: 256: 255: 253: 251: 248: 247: 240: 236: 235: 233: 231: 228: 227: 220: 216: 215: 213: 211: 208: 207: 203: 200: 196: 195: 188: 184: 183: 181: 178: 177: 170: 166: 165: 163: 159: 154: 153: 139: 135: 125: 121: 118: 114: 113: 111: 108: 104: 103: 98: 90: 87: 86: 81: 73: 69: 64: 54: 50: 45: 41: 40: 36: 30: 19: 18:Blood lactate 4996: 4935: 4921:Furazolidone 4911:Policresulen 4814:Flutrimazole 4799:Butoconazole 4779:Ketoconazole 4749:Clotrimazole 4709:Sulfonamides 4688: 4671:Oxyquinoline 4507:the original 4502: 4447: 4440: 4431: 4421: 4409:. Retrieved 4404: 4395: 4383:. Retrieved 4379:the original 4369: 4357:. Retrieved 4332:. Retrieved 4322: 4310:. Retrieved 4300: 4288:. Retrieved 4278: 4259: 4255: 4245: 4236: 4227: 4218: 4195: 4189: 4175: 4158: 4123: 4119: 4109: 4030: 4026: 4016: 3979: 3975: 3965: 3932: 3928: 3922: 3887: 3883: 3873: 3841:(1): 34–45. 3838: 3834: 3823: 3788: 3784: 3774: 3741: 3737: 3731: 3696: 3692: 3682: 3647: 3643: 3630: 3605: 3601: 3555: 3551: 3545: 3524: 3480: 3476: 3443: 3439: 3433: 3404: 3398: 3379: 3373: 3354: 3348: 3329: 3323: 3307: 3302: 3288: 3276:. Retrieved 3270: 3260: 3241: 3237: 3181: 3177: 3167: 3132: 3128: 3118: 3083: 3079: 3069: 3037:(2): 89–95. 3034: 3030: 3020: 2983: 2979: 2969: 2957:. Retrieved 2952: 2912: 2908: 2860: 2856: 2846: 2834:. Retrieved 2824: 2779: 2775: 2750:. Retrieved 2746: 2737: 2730:-Lactic acid 2683:(5): 771–8. 2680: 2676: 2669: 2660: 2654: 2601: 2515: 2503: 2482: 2470: 2455: 2447:Flanders red 2429:Some beers ( 2428: 2416:In lists of 2415: 2380: 2363: 2361:properties. 2355:disinfectant 2344: 2321:syndiotactic 2307: 2280: 2222:Upper limit 2219:Lower limit 2206:venipuncture 2188: 2168: 2163: 2157: 2129: 2069: 2054: 2019: 1992: 1944: 1892: 1840: 1814:mitochondria 1806: 1756: 1728: 1681: 1646:lactonitrile 1638:acetaldehyde 1635: 1613: 1609: 1579: 1574: 1570:thermophilus 1569: 1565: 1558: 1552: 1546: 1542: 1537: 1533: 1528: 1522: 1516: 1512: 1499: 1466:acetaldehyde 1458:fermentation 1455: 1447: 1429: 1427: 1394: 1384: 1371: 1263: 1186:fermentation 1167:In animals, 1166: 1107: 1097: 1081: 1071: 1039: 1034: 1026: 983: 980:organic acid 975: 974: 870: 771:Butyric acid 766:Malonic acid 684: 654: 415:RTECS number 239:ChEMBL330546 100:Identifiers 83:Other names 33:Lactic acid 29: 27:Organic acid 4832:Terconazole 4809:Oxiconazole 4804:Omoconazole 4789:Azanidazole 4774:Tioconazole 4769:Isoconazole 4727:Antifungals 4694:Acetic acid 4689:Lactic acid 4661:Dequalinium 4639:derivatives 4603:Clindamycin 4598:Mepartricin 4593:Carfecillin 4565:Antibiotics 4552:antiseptics 4262:(1): 4–10. 4256:HortScience 3244:: 141–158. 2836:23 November 2423:food energy 2401:, and some 2359:keratolytic 2324:polylactide 2190:Blood tests 2082:of several 1777:Krebs cycle 1622:acetic acid 1318:intravenous 1122:hygroscopic 1088:enantiomers 1066:acetic acid 1019:biochemical 976:Lactic acid 746:Acetic acid 663:3.86, 15.1 567:Properties 558:CC(O)C(=O)O 277:100.000.017 88:Lactic acid 6707:Categories 4931:Protiofate 4901:Clodantoin 4876:Ciclopirox 4764:Ornidazole 4754:Miconazole 4736:Imidazoles 4651:Clioquinol 4608:Pentamycin 4583:Hachimycin 4573:Candicidin 4334:27 October 4312:27 October 4290:27 October 3316:0792306252 3278:23 January 3135:(1): 2–8. 2585:References 2522:hard water 2491:270 or as 2489:INS number 2458:malic acid 2331:polyesters 2283:childbirth 2149:inhibitory 2134:and early 1843:glycolysis 1793:Cori cycle 1752:glycolysis 1723:See also: 1689:endogenous 1650:hydrolysis 1538:bulgaricus 1515:bacteria: 1452:Production 1235:endogenous 1190:metabolism 1031:acyl group 882:Pictograms 799:2-Propanol 794:1-Propanol 707:kJ/g, 3.61 677:combustion 602:Molar mass 461:3Q6M5SET7W 447:F9S9FFU82N 440:3B8D35Y7S4 335:IUPHAR/BPS 250:ChemSpider 156:3D model ( 138:10326-41-7 107:CAS Number 4916:Nifuratel 4855:Natamycin 4824:Triazoles 4759:Econazole 4637:Quinoline 4627:Acetarsol 4620:compounds 4142:0085-2538 3815:205621542 3497:1439-6319 3265:Roth SM. 3198:1555-9041 2986:: 38–48. 2752:5 January 2677:Biometals 2431:sour beer 2411:sourdough 2351:cosmetics 2317:catalysts 2255:Arterial 2141:GABAergic 2136:postnatal 2122:studies. 2084:mammalian 2070:Although 1762:Oxidation 1731:sprinting 1445:in 1895. 1425:in 1873. 1326:potassium 1286:galactose 873:labelling 645:Miscible 479:UN number 422:OD2800000 298:200-018-0 290:EC Number 219:CHEBI:422 91:Milk acid 4850:Nystatin 4842:Polyenes 4478:Archived 4407:. US FDA 4355:. US FDA 4228:MoreBeer 4198:. Rome: 4150:11532105 4082:Archived 4059:21687795 4008:21602909 3957:13966338 3949:21593390 3914:21084619 3865:21209187 3807:19943846 3766:18780083 3758:17659524 3723:15131240 3674:21593331 3622:20633934 3572:15308499 3505:29322250 3296:. NNFCC. 3216:35998977 3207:10101555 3159:17167253 3110:18216213 3061:19239634 3012:19088910 2931:21454438 2887:19885119 2816:23650363 2705:11615864 2697:19288211 2532:See also 2493:E number 2366:oxaluria 2202:arterial 2164:in vitro 2132:prenatal 2041:CH(OH)CO 1975:CH(OH)CO 1931:CH(OH)CO 1799:glycogen 1766:pyruvate 1764:back to 1739:pyruvate 1715:(GPCR). 1709:-coupled 1667:glycerol 1440:pharmacy 1374:ischemia 1344:isotonic 1333:chloride 1316:. 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Index

Blood lactate


Preferred IUPAC name
CAS Number
50-21-5
79-33-4
10326-41-7
JSmol
Interactive image
B01180
Beilstein Reference
ChEBI
CHEBI:422
ChEMBL
ChEMBL330546
ChemSpider
96860
ECHA InfoCard
100.000.017
Edit this at Wikidata
EC Number
E number
(preservatives)
Gmelin Reference
IUPHAR/BPS
2932
KEGG
D00111
C00186

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