196:, operationally defined as a reduction in the animal's intake of sucrose without any associated change in its intake of water and used as an indicator of depression in the animal model. Of potential clinical relevance, the researchers identified links between the occurrence of anhedonia and significant changes in levels of
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Grippo uses animal models to identify significant associations between stress, mood, and cardiovascular dysregulation. Several of her studies have used rats to explore how mood influences autonomic nervous system activity and immune response, and its potential impact on cardiovascular functioning. In
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Grippo, Angela J.; Sullivan, Nicole R.; Damjanoska, Katerina J.; Crane, James W.; Carrasco, Gonzalo A.; Shi, Ju; Chen, Zhuo; Garcia, Francisca; Muma, Nancy A. (2004-12-24). "Chronic mild stress induces behavioral and physiological changes, and may alter serotonin 1A receptor function, in male and
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and depression in prairie vole, and associated disturbances in neuroendocrine activation that may be of clinical importance for understanding cardiovascular complications associated with stress. One of her studies investigated the hypothesis that social and environmental stressors, including long
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Distinguished
Scientific Award for an Early Career Contribution to Psychology in the area of health psychology. Her award citation emphasized "her creative contributions in investigating the association between depression and cardiovascular disease in preclinical animal models... advance
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In addition to her award-winning research program, Grippo writes popular articles to help people better understand themselves and their circumstances. Her article "Why Reveal Your
Disability or ‘Hidden Identity’ at Work?" encourages people to remain open about their disabilities, such as
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Carnevali, L.; Mastorci, F.; Graiani, G.; Razzoli, M.; Trombini, M.; Pico-Alfonso, M.A.; Arban, R.; Grippo, A.J.; Quaini, F. (2012). "Social defeat and isolation induce clear signs of a depression-like state, but modest cardiac alterations in wild-type rats".
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where she obtained an MA in 2000, and a PhD in
Behavioral Neuroscience in 2003, under the supervision of Alan Kim Johnson. Her dissertation used a rodent model to explore neurobiological mechanisms associated with heart disease.
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Grippo, A. J., Gerena, D., Huang, J., Kumar, N., Shah, M., Ughreja, R., & Carter, C. S. (2007). Social isolation induces behavioral and neuroendocrine disturbances relevant to depression in female and male prairie voles.
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236:. In this study, socially isolated prairie voles exhibited depressive behavior as compared to a control group (living in pairs). Social isolation was also found to alter the expression of Connexin 43 in the
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Grippo, A. J., & Johnson, A. K. (2009). Stress, depression and cardiovascular dysregulation: a review of neurobiological mechanisms and the integration of research from preclinical disease models.
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Grippo, A. J., Trahanas, D. M., Zimmerman II, R. R., Porges, S. W., & Carter, C. S. (2009). Oxytocin protects against negative behavioral and autonomic consequences of long-term social isolation.
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Grippo, Angela J.; Francis, Joseph; Beltz, Terry G.; Felder, Robert B.; Johnson, Alan Kim (2005). "Neuroendocrine and cytokine profile of chronic mild stress-induced anhedonia".
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Grippo, Angela J.; Moffitt, Julia A.; Henry, Matthew K.; Firkins, Rachel; Senkler, Jonathan; McNeal, Neal; Wardwell, Joshua; Scotti, Melissa-Ann L.; Dotson, Ashley (2015).
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Grippo, A. J., Francis, J., Beltz, T. G., Felder, R. B., & Johnson, A. K. (2005). Neuroendocrine and cytokine profile of chronic mild stress-induced anhedonia.
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661:"Stress, depression and cardiovascular dysregulation: A review of neurobiological mechanisms and the integration of research from preclinical disease models"
171:. Grippo joined the faculty of the Department of Psychology at Northern Illinois University in 2008. Her research has been supported by grants from the
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987:"Altered Connexin 43 and Connexin 45 Protein Expression in the Heart as a Function of Social and Environmental Stress in the Prairie Vole"
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Grippo, A. J., & Johnson, A. K. (2002). Biological mechanisms in the relationship between depression and heart disease.
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Grippo, Angela J.; Gerena, Davida; Huang, Jonathan; Kumar, Narmda; Shah, Maulin; Ughreja, Raj; Sue Carter, C. (2007).
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167:(2004-2008). During her second postdoc, Grippo studied neuroendocrine functioning in relation to social behavior in
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CARTER, C; GRIPPO, A; POURNAJAFINAZARLOO, H; RUSCIO, M; PORGES, S (2008), "Oxytocin, vasopressin and sociality",
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718:"The Utility of Animal Models in Understanding Links between Psychosocial Processes and Cardiovascular Health"
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understanding of the connections among depression, stress, and physical disease in humans."
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APA Distinguished
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Grippo's articles emphasize brain-body interactions, stress, and health issues.
613:"Behavioral autonomic and endocrine regulation in depression and heart disease"
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228:. These proteins, located in the heart, play an important role in
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163:(2003-2004), Grippo took a second postdoctoral position at the
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Grippo, Angela J.; Cushing, Bruce S.; Carter, C Sue (2007).
392:"Why Reveal Your Disability or 'Hidden Identity' at Work?"
127:. She and her colleague Joseph Magiano write a column for
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464:"Dr. Angela Grippo, PhD | Society for Health Psychology"
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known for her research on stress, mood disorders, and
147:. She received her Bachelors of Science degree from
325:"2012 APA Distinguished Scientific Award recipients"
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216:term social isolation, may alter the expression of
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16:American neuroscientist and health psychologist
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123:. She embraces the ideas of individuality and
659:Grippo, Angela J.; Johnson, Alan Kim (2001).
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575:, vol. 170, Elsevier, pp. 331–336,
159:After a one-year postdoctoral fellowship at
488:"Neurotree - Angela J. Grippo Family Tree"
192:, exposure to unpredictable stress led to
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278:Neuroscience & Biobehavioral Reviews
151:in 1998. She went to graduate school at
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416:"Three Tips for Staying Heart Healthy"
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1071:21st-century American psychologists
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133:The Wide Wide World of Psychology.
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468:Society for Health Psychology
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1066:American women psychologists
1003:10.3109/10253890.2014.979785
532:10.1097/psy.0b013e31802f054b
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105:Northern Illinois University
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1101:21st-century American women
248:Representative publications
238:left ventricle of the heart
234:intercellular communication
200:and stress hormones (e.g.,
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716:Grippo, Angela J. (2011).
1086:University of Iowa alumni
936:Physiology & Behavior
827:Physiology & Behavior
788:10.1007/s00213-004-2103-4
677:10.1080/10253890802046281
255:Physiology & Behavior
110:Grippo received the 2012
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882:Psychoneuroendocrinology
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188:one of her studies with
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774:cycling female rats".
520:Psychosomatic Medicine
101:cardiovascular disease
350:American Psychologist
218:gap junction proteins
356:(8): 632–634. 2012.
145:Park Ridge, Illinois
230:cardiac rhythmicity
190:Sprague−Dawley rats
97:health psychologist
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226:Connexin 45
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311:References
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139:Biography
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