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Amobarbital

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Eli Lilly manufactured amobarbital under the brand name Amytal until it was discontinued in the 1980s and replaced largely by the benzodiazepine family of drugs. Amytal was also widely abused. Street names for amobarbital include "blues", "blue angels", "blue birds", "blue devils", and "blue heavens"
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season 3, episode 7, "Tourist Season", Dr. Quentin Q. Quinn, voiced by Brett Butler, uses "sodium amytal" to induce amnesia in a group of tourists, in order to prevent them from taking action against Sealab as a result of a hare-brained scheme by Capt. Murphy. He gives the dose in a free alcoholic
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found him to be in an emotional state. She called Walker's psychiatrist who arrived and administered amobarbital for sedation. Walker was allegedly drinking prior to his emotional outburst, and it is believed the combination of amobarbital and alcohol resulted in a severe reaction. As a result, he
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Some side effects of overdose include confusion (severe); decrease in or loss of reflexes; drowsiness (severe); fever; irritability (continuing); low body temperature; poor judgment; shortness of breath or slow or troubled breathing; slow heartbeat; slurred speech; staggering; trouble in sleeping;
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duties. This use has since been discontinued as the powerful sedation, cognitive impairment, and dis-coordination induced by the drug greatly reduced soldiers' usefulness in the field. Amobarbital was once manufactured in the US by Eli Lilly Pharmaceuticals under the brand name Amytal in capsule
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and amobarbital, were both manufactured by Eli Lilly until the late 1990s. However, as the popularity of benzodiazepines increased, prescriptions for these medications became increasingly rare beginning in the mid to late 1980s.
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in the US under the brand name Amytal in bright blue bullet shaped capsules (known as Pulvules) or pink tablets (known as Diskets) containing 50, 100, or 200 milligrams of the drug. The drug was also manufactured generically.
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form. It was discontinued in the early 1980s, largely replaced by the benzodiazepine family of drugs. Amobarbital was also widely abused, known on the streets as "blue heavens" because of their blue capsule.
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at the University of Wisconsin to circumvent inhibitions in psychiatric patients. The use of amobarbital as a truth serum has lost credibility due to the discovery that a subject can be coerced into having a
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Soine PJ, Soine WH (November 1987). "High-performance liquid chromatographic determination of the diastereomers of 1-(beta-D-glucopyranosyl)amobarbital in urine".
1358:[Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese). 3448: 1472:
Stewart S, Lesnefsky EJ, Chen Q (May 2009). "Reversible blockade of electron transport with amobarbital at the onset of reperfusion attenuates cardiac injury".
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Amobarbital has been used in a study to inhibit mitochondrial electron transport in the rat heart in an attempt to preserve mitochondrial function following
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Ben Kimmelman, Captain, 28th Infantry: The assumptions were that this would have some kind of cathartic effect, the sodium amytal, which the men called
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Miller LG, Deutsch SI, Greenblatt DJ, Paul SM, Shader RI (1988). "Acute barbiturate administration increases benzodiazepine receptor binding in vivo".
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Amobarbital was widely misused, known as "Blue Heavens" on the street. Amytal, as well as Tuinal, a combination drug containing equal quantities of
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episode 14, Man Zeun (portrayed by Princeton Lock) uses sodium amytal in an attempt to force gambling addict Lee Fat into paying debts.
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derivatives. In particular, in order to make amobarbital, α-ethyl-α-isoamylmalonic ester is reacted with urea (in the presence of
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beverage as a parting gift before the tourists leave, and in quantities he describes that could "make an elephant forget".
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properties. It is a white crystalline powder with no odor and a slightly bitter taste. It was first synthesized in
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unusual movements of the eyes; weakness (severe). Severe overdose may result in death without intervention.
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passed out and stopped breathing, and all efforts to resuscitate him failed. Walker died at 32 years old.
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When given slowly by an intravenous route, sodium amobarbital has a reputation for acting as a so-called
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Amobarbital (5-ethyl-5-isoamylbarbituric acid), like all barbiturates, is synthesized by reacting
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InChI=1S/C11H18N2O3/c1-4-11(6-5-7(2)3)8(14)12-10(16)13-9(11)15/h7H,4-6H2,1-3H3,(H2,12,13,14,15,16)
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Maynert EW (October 1965). "The alcoholic metabolites of pentobarbital and amobarbital in man".
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Tang BK, Kalow W, Grey AA (July 1978). "Amobarbital metabolism in man: N-glucoside formation".
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Stocks JT (September 1998). "Recovered memory therapy: a dubious practice technique".
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is used to make the unnamed protagonist respond to questioning about his activities.
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You know, the most effective artillery piece of the Germans was the 88 and this was
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killed himself in Australia in 1968 using the drug in combination with alcohol.
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Bleckwenn WJ (1930). "Sodium amytal in certain nervous and mental conditions".
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Amobarbital has been known to decrease the effects of hormonal birth control.
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If amobarbital is taken for extended periods of time, physiological and
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in 1923. It is considered a short to intermediate acting barbiturate.
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The drug has been used to gain confessions from murderers such as
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The following drugs should be avoided when taking amobarbital:
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study in rat thalamic slices, amobarbital worked by activating
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Research Communications in Chemical Pathology and Pharmacology
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The drug may be used intravenously to interview patients with
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and may be life-threatening. Amobarbital was manufactured by
579: 436: 278: 742:, while at the same time increasing burst duration and mean 481: 4841: 2018: 1778:"Amobarbital | Memorial Sloan Kettering Cancer Center" 1506: 1143: 926: 416: 1867:"blue devils (amobarbital) - Memidex dictionary/thesaurus" 1267:) claims that the drug leaves a patient so susceptible to 1165:
On the night of August 28, 1951, the housekeeper of actor
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The Journal of Pharmacology and Experimental Therapeutics
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5-ethyl-5-(3-methylbutyl)-1,3-diazinane-2,4,6-trione
1302:In 2022, in "Diophantine Pseudonym", Episode 06 of 1423:Kim HS, Wan X, Mathers DA, Puil E (October 2004). 6150:Unsorted benzodiazepine site positive modulators: 1422: 6202: 1930:"Episode review: Columbo A Deadly State of Mind" 669:as the soluble sodium salt) is a drug that is a 344: 826:to form 1-(beta-D-glucopyranosyl)-amobarbital. 318: 1980: 1765:, because the sodium amytal was a blue tablet. 1386:"Dosage Form Names and Product Identification" 770:A 1988 study found that amobarbital increases 731:, which decreased input resistance, depressed 82: 3583: 2995:Serotonin antagonists and reuptake inhibitors 1966: 1576: 1238:, the protagonist Harry Tasker (portrayed by 3599: 3384: 692:can develop. Amobarbital withdrawal mimics 3590: 3576: 1973: 1959: 1909:A Deadly State of Mind | Echoes of Columbo 1603: 1390:American Journal of Health-System Pharmacy 518: 495: 384: 1809: 1790: 1713: 1638: 1448: 404: 6226:Drugs developed by Eli Lilly and Company 1742:Battle of the Bulge - program transcript 1702:Journal of Psychiatry & Neuroscience 920: 784:(in descending order), but greater than 780:with less potency than secobarbital and 61:Micromedex Detailed Consumer Information 1549: 861: 491: 364: 6203: 1695: 1657: 1651: 1350: 1184: 1153: 509: 221: 193: 3571: 1954: 1828: 1383: 1248:Law & Order: Special Victims Unit 464: 444: 205: 77: 59: 6191:GABA metabolism/transport modulators 1883: 1232:In the 1994 comedic action thriller 916: 189:(Special prescription form required) 130: 5808:Trichloroethane (methyl chloroform) 1822: 822:to form 3'-hydroxyamobarbital, and 424: 335: 13: 6231:Substances discovered in the 1920s 4871:11-Methoxy-12-hydroxydehydrokavain 1847:from the original on April 5, 2005 1738:"Use of sodium amytal during WWII" 796:> phenobarbital > barbital) 14: 6242: 5618:Acetylglycinamide chloral hydrate 2700:Acetylglycinamide chloral hydrate 1831:"Truth Serum: A Possible Weapon" 1384:Winek, Charles L. (1965-02-01). 1131: 549: 543: 36: 27: 6038:Menthyl isovalerate (validolum) 1922: 1900: 1877: 1859: 1803: 1784: 1770: 1748:from the original on 2009-03-14 1730: 1689: 1429:British Journal of Pharmacology 1366:from the original on 2023-08-03 1173:The British actor and comedian 1109: 712: 636:Key:VIROVYVQCGLCII-UHFFFAOYSA-N 181: 4987:Allopregnanolone (brexanolone) 1632: 1597: 1570: 1543: 1500: 1465: 1416: 1377: 1344: 1199:, a combination of amytal and 829: 555: 537: 228:Psychotropic Schedule III 170: 157: 1: 6183:Receptor/signaling modulators 4739:Ampelopsin (dihydromyricetin) 1829:Leung R (February 11, 2009). 1274:In 2003, the animated series 813: 611:O=C1NC(=O)NC(=O)C1(CCC(C)C)CC 5933:ergoloid (dihydroergotoxine) 5018:anabolic-androgenic steroids 3800:Butabarbital/Secbutabarbital 3605:receptor positive modulators 1618:10.1016/0378-4347(87)80468-1 1126: 737:ventrobasal and intralaminar 7: 4573:Triflunordazepam (Ro5-2904) 3226:Tetracyclic antidepressants 3040:Tetracyclic antidepressants 1884:Hart, Harvey (1975-04-27), 1696:McCall WV (November 1992). 1315: 1181:due to their blue capsule. 1117: 908:and return soldiers to the 834: 818:Amobarbital undergoes both 10: 6247: 4901:5,6,7,8-Tetrahydroyangonin 1486:10.1016/j.trsl.2009.02.003 1293:In 2016, television drama 898:United States armed forces 889:, sometimes combined with 527:Chemical and physical data 6176: 5826: 5594: 5531: 5498: 5465: 5437: 5151: 5093:Pregnanolone (eltanolone) 4972: 4929: 4840: 4812: 4724: 4606: 4048: 3735: 3636:Chlorobutanol (cloretone) 3611: 3429: 3382: 3354: 3321: 3301: 3247: 3203:Tricyclic antidepressants 3188: 3176: 3119: 3061: 3017:Tricyclic antidepressants 2985: 2922: 2910: 2839: 2687: 2624: 2591: 2573: 2505: 2452: 2409: 2381: 2323: 2200: 2057: 2009: 1997: 1641:Wisconsin Medical Journal 1606:Journal of Chromatography 1196:An Expensive Place to Die 644: 619: 599: 577: 564: 531: 526: 507: 475: 455: 435: 415: 395: 375: 355: 330: 309: 289: 284: 272: 259: 247: 239: 147: 142: 117: 97: 67: 49: 44: 35: 26: 6187:GABA receptor modulators 6097:sulfonmethane (sulfonal) 2788:Sulfonmethane (sulfonal) 1362:(published 2023-04-04). 1337: 1296:A Fist Within Four Walls 690:psychological dependence 3275:Atypical antipsychotics 3089:Atypical antipsychotics 1685:(subscription required) 1360:Diário Oficial da União 904:in an attempt to treat 772:benzodiazepine receptor 6073:Retigabine (ezogabine) 5349:Lirequinil (Ro41-3696) 4916:7,8-Dihydromethysticin 4906:5,6-Dehydromethysticin 3785:Benzylbutylbarbiturate 3449:Chlorophenylalkyldiols 3257:Typical antipsychotics 3071:Typical antipsychotics 1887:A Deadly State of Mind 1474:Translational Research 1441:10.1038/sj.bjp.0705974 1251:episode "Repression" ( 1227:A Deadly State of Mind 930: 733:burst and tonic firing 1934:THE COLUMBOPHILE BLOG 1811:US patent 1856792 1287:Hellraiser: Hellworld 1240:Arnold Schwarzenegger 1160:Andres English-Howard 924: 698:Eli Lilly and Company 323:64-43-7 (sodium salt) 6128:constituents (e.g., 5912:Deuterated etifoxine 4974:Neuroactive steroids 4944:Apronal (apronalide) 4796:constituents (e.g., 4413:N-Desalkylflurazepam 3406:Gabapentin enacarbil 2454:Neuroactive steroids 2424:Apronal (apronalide) 1792:GB patent 191008 1402:10.1093/ajhp/22.2.82 862:Unapproved/off-label 166:(Psychoactive drugs) 5921:dihydroergocryptine 5233:Pyrazolopyrimidines 4891:5,6-Dihydroyangonin 4876:7,8-Dihydroyangonin 4063:3-Hydroxyphenazepam 3905:Methylphenobarbital 1912:, 16 September 2020 1672:10.1093/sw/43.5.423 1284:In the 2005 movie, 1253:Season 3, Episode 1 1185:Cultural references 1154:Society and culture 896:It was used by the 673:derivative. It has 661:(formerly known as 23: 6015:4-O-methylhonokiol 5678:Dichloralphenazone 5576:Methylmethaqualone 5153:Nonbenzodiazepines 4866:Desmethoxyyangonin 4861:11-Hydroxyyangonin 4856:11-Methoxyyangonin 4851:10-Methoxyyangonin 4238:Ethyl carfluzepate 3840:Cyclopentobarbital 3471:Diethylpropanediol 2753:Dichloralphenazone 2669:Methylmethaqualone 2507:Nonbenzodiazepines 2034:Diethylpropanediol 1521:10.1007/BF00216067 1509:Psychopharmacology 931: 893:to prevent sleep. 232:SE: Förteckning IV 19: 6221:German inventions 6198: 6197: 6158:MRK-409 (MK-0343) 5929:dihydroergotamine 5872:potassium bromide 5866:compounds (e.g., 5813:Trichloroethylene 5581:Nitromethaqualone 5500:Pyrazolopyridines 5002:3α-Androstanediol 4896:7,8-Dihydrokavain 4248:Ethyl loflazepate 4025:Thiotetrabarbital 3641:Ethanol (alcohol) 3565: 3564: 3317: 3316: 3115: 3114: 2835: 2834: 2716:Potassium bromide 2674:Nitromethaqualone 2182:Thiotetrabarbital 2029:Ethanol (alcohol) 1213:Gravity's Rainbow 1142:derivatives with 977:Antihypertensives 917:Contraindications 872:William Bleckwenn 748:chloride channels 656: 655: 590:Interactive image 477:CompTox Dashboard 225: 209: 197: 184: 173: 161: 80: 6238: 5917:Dihydroergolines 5834:3-Hydroxybutanal 5467:Piperidinediones 5200:Imidazopyridines 4734:6-Methylapigenin 4666:Hydroxyphenamate 4538:SH-053-R-CH3-2′F 4243:Ethyl dirazepate 4123:Chlordiazepoxide 4015:Thiobutabarbital 3727:Trifluoroethanol 3717:Trichloroethanol 3707:-Pentanol (2M2B) 3601: 3592: 3585: 3578: 3569: 3568: 3490:muscle relaxants 3393: 3390: 3186: 3185: 2920: 2919: 2857:4-Fluorophenibut 2593:Piperidinediones 2467:Allopregnanolone 2049:Trichloroethanol 2007: 2006: 1975: 1968: 1961: 1952: 1951: 1945: 1944: 1942: 1941: 1926: 1920: 1919: 1918: 1917: 1904: 1898: 1897: 1896: 1895: 1881: 1875: 1874: 1863: 1857: 1856: 1854: 1852: 1826: 1820: 1819: 1818: 1814: 1807: 1801: 1800: 1799: 1795: 1788: 1782: 1781: 1774: 1768: 1767: 1754: 1753: 1734: 1728: 1727: 1717: 1693: 1687: 1686: 1683: 1655: 1649: 1648: 1636: 1630: 1629: 1601: 1595: 1594: 1574: 1568: 1567: 1547: 1541: 1540: 1504: 1498: 1497: 1469: 1463: 1462: 1452: 1420: 1414: 1413: 1381: 1375: 1374: 1372: 1371: 1348: 1255:), a therapist ( 1135: 1030:Cyclophosphamide 929:of Amytal sodium 879:" of the event. 809: 735:, especially in 694:delirium tremens 652: 651: 592: 572: 557: 551: 545: 539: 522: 511: 500: 499: 485: 483: 468: 448: 428: 408: 388: 368: 348: 338: 337: 322: 264: 223: 220: 207: 204: 195: 192: 183: 180: 172: 169: 159: 156: 134: 90: 79: 76: 63: 40: 31: 24: 22: 18: 6246: 6245: 6241: 6240: 6239: 6237: 6236: 6235: 6201: 6200: 6199: 6194: 6172: 6130:isovaleric acid 6093:Sulfonylalkanes 5991:Hopantenic acid 5975:tolfenamic acid 5963:flufenamic acid 5925:dihydroergosine 5868:lithium bromide 5827:Others/unsorted 5822: 5683:Dichloromethane 5658:Chloral hydrate 5653:Chloral betaine 5590: 5527: 5494: 5461: 5433: 5162:Cyclopyrrolones 5147: 5053:Etiocholanolone 4968: 4925: 4886:5-Hydroxykavain 4836: 4808: 4720: 4602: 4050:Benzodiazepines 4044: 3855:Ethallobarbital 3850:Enallylpropymal 3731: 3712:Tribromoethanol 3699:-Butanol (2M2P) 3645:alcoholic drink 3607: 3604: 3596: 3566: 3561: 3425: 3388: 3378: 3350: 3313: 3297: 3243: 3190:Antidepressants 3181: 3172: 3143:Dexmedetomidine 3124: 3111: 3057: 2987:Antidepressants 2981: 2942:Diphenhydramine 2915: 2906: 2844: 2831: 2820:Isovaleric acid 2783:Sulfonylalkanes 2738:Chloral hydrate 2733:Chloral betaine 2711:Lithium bromide 2683: 2620: 2587: 2569: 2501: 2448: 2405: 2377: 2319: 2202:Benzodiazepines 2196: 2102:Ethallobarbital 2053: 2002: 1993: 1979: 1949: 1948: 1939: 1937: 1928: 1927: 1923: 1915: 1913: 1906: 1905: 1901: 1893: 1891: 1882: 1878: 1871:www.memidex.com 1865: 1864: 1860: 1850: 1848: 1827: 1823: 1816: 1808: 1804: 1797: 1789: 1785: 1776: 1775: 1771: 1751: 1749: 1736: 1735: 1731: 1694: 1690: 1684: 1656: 1652: 1637: 1633: 1602: 1598: 1575: 1571: 1548: 1544: 1505: 1501: 1470: 1466: 1421: 1417: 1382: 1378: 1369: 1367: 1349: 1345: 1340: 1318: 1309:The Lost Symbol 1187: 1156: 1148:sodium ethoxide 1129: 1120: 1112: 1020:Chloramphenicol 995:Benzodiazepines 938:Antiarrhythmics 919: 864: 837: 832: 824:N-glucosidation 816: 807: 804: 728: 715: 647: 645: 640: 637: 632: 627: 626: 615: 612: 607: 606: 595: 570: 560: 554: 548: 542: 503: 479: 471: 451: 431: 411: 391: 371: 351: 334: 326: 305: 302: 297: 296: 262: 241:Pharmacokinetic 235: 138: 100: 93: 17: 12: 11: 5: 6244: 6234: 6233: 6228: 6223: 6218: 6213: 6196: 6195: 6177: 6174: 6173: 6171: 6170: 6165: 6160: 6155: 6146: 6145: 6138:valerenic acid 6123: 6118: 6108: 6090: 6085: 6080: 6075: 6070: 6065: 6060: 6055: 6050: 6045: 6040: 6035: 6030: 6008: 6003: 5998: 5993: 5988: 5983: 5978: 5967:mefenamic acid 5956: 5951: 5946: 5941: 5936: 5914: 5909: 5904: 5899: 5894: 5889: 5884: 5879: 5876:sodium bromide 5861: 5851: 5846: 5841: 5836: 5830: 5828: 5824: 5823: 5821: 5820: 5815: 5810: 5805: 5800: 5795: 5790: 5785: 5780: 5775: 5770: 5765: 5760: 5755: 5750: 5745: 5743:Methoxypropane 5740: 5738:Methoxyflurane 5735: 5730: 5725: 5720: 5715: 5710: 5705: 5700: 5698:Ethyl chloride 5695: 5690: 5685: 5680: 5675: 5670: 5665: 5660: 5655: 5650: 5645: 5640: 5635: 5630: 5625: 5620: 5615: 5610: 5604: 5602: 5592: 5591: 5589: 5588: 5583: 5578: 5573: 5568: 5563: 5558: 5553: 5548: 5543: 5537: 5535: 5533:Quinazolinones 5529: 5528: 5526: 5525: 5520: 5515: 5510: 5504: 5502: 5496: 5495: 5493: 5492: 5487: 5482: 5477: 5471: 5469: 5463: 5462: 5460: 5459: 5454: 5449: 5443: 5441: 5435: 5434: 5432: 5431: 5426: 5421: 5416: 5411: 5406: 5401: 5396: 5391: 5386: 5381: 5376: 5371: 5366: 5361: 5356: 5351: 5346: 5341: 5336: 5331: 5326: 5321: 5316: 5311: 5306: 5301: 5296: 5291: 5286: 5276: 5275: 5270: 5265: 5260: 5255: 5250: 5245: 5240: 5228: 5227: 5222: 5217: 5212: 5207: 5195: 5194: 5189: 5184: 5179: 5174: 5169: 5157: 5155: 5149: 5148: 5146: 5145: 5140: 5135: 5130: 5125: 5120: 5115: 5110: 5105: 5100: 5095: 5090: 5085: 5080: 5075: 5070: 5065: 5060: 5055: 5050: 5045: 5040: 5035: 5030: 5025: 5020: 5014: 5009: 5004: 4999: 4994: 4989: 4984: 4978: 4976: 4970: 4969: 4967: 4966: 4961: 4956: 4951: 4946: 4941: 4935: 4933: 4927: 4926: 4924: 4923: 4918: 4913: 4908: 4903: 4898: 4893: 4888: 4883: 4878: 4873: 4868: 4863: 4858: 4853: 4847: 4845: 4838: 4837: 4835: 4834: 4829: 4824: 4818: 4816: 4810: 4809: 4807: 4806: 4801: 4791: 4786: 4781: 4776: 4771: 4766: 4761: 4756: 4751: 4746: 4741: 4736: 4730: 4728: 4722: 4721: 4719: 4718: 4713: 4708: 4703: 4698: 4693: 4688: 4683: 4678: 4673: 4668: 4663: 4658: 4653: 4648: 4643: 4638: 4633: 4628: 4623: 4618: 4612: 4610: 4604: 4603: 4601: 4600: 4595: 4590: 4585: 4580: 4575: 4570: 4565: 4560: 4555: 4550: 4545: 4540: 4535: 4530: 4525: 4520: 4515: 4510: 4505: 4500: 4495: 4490: 4485: 4480: 4475: 4470: 4465: 4460: 4455: 4450: 4445: 4440: 4435: 4430: 4425: 4420: 4415: 4410: 4405: 4400: 4395: 4390: 4385: 4380: 4375: 4370: 4365: 4360: 4355: 4350: 4345: 4340: 4335: 4330: 4325: 4320: 4315: 4310: 4305: 4300: 4295: 4290: 4285: 4280: 4275: 4270: 4265: 4260: 4255: 4250: 4245: 4240: 4235: 4230: 4225: 4220: 4215: 4210: 4205: 4200: 4195: 4190: 4185: 4180: 4175: 4170: 4165: 4160: 4155: 4150: 4145: 4140: 4135: 4130: 4125: 4120: 4115: 4110: 4105: 4100: 4095: 4090: 4085: 4080: 4075: 4070: 4065: 4060: 4054: 4052: 4046: 4045: 4043: 4042: 4037: 4032: 4027: 4022: 4017: 4012: 4007: 4002: 3997: 3992: 3987: 3982: 3977: 3972: 3967: 3962: 3957: 3955:Propylbarbital 3952: 3947: 3942: 3937: 3932: 3927: 3922: 3917: 3912: 3907: 3902: 3897: 3892: 3887: 3882: 3877: 3872: 3867: 3862: 3857: 3852: 3847: 3842: 3837: 3832: 3830:Crotylbarbital 3827: 3822: 3817: 3812: 3807: 3802: 3797: 3795:Brophebarbital 3792: 3790:Brallobarbital 3787: 3782: 3777: 3772: 3767: 3762: 3757: 3752: 3747: 3741: 3739: 3733: 3732: 3730: 3729: 3724: 3719: 3714: 3709: 3701: 3693: 3688: 3683: 3678: 3676:Methylpentynol 3673: 3668: 3663: 3658: 3653: 3648: 3638: 3633: 3628: 3623: 3617: 3615: 3609: 3608: 3602: 3595: 3594: 3587: 3580: 3572: 3563: 3562: 3560: 3559: 3554: 3549: 3544: 3539: 3537:Passion flower 3534: 3524: 3519: 3518: 3517: 3512: 3507: 3502: 3497: 3483: 3478: 3473: 3468: 3467: 3466: 3461: 3456: 3446: 3445: 3444: 3433: 3431: 3427: 3426: 3424: 3423: 3418: 3413: 3408: 3403: 3397: 3395: 3386: 3380: 3379: 3377: 3376: 3371: 3366: 3360: 3358: 3352: 3351: 3349: 3348: 3343: 3338: 3333: 3327: 3325: 3319: 3318: 3315: 3314: 3312: 3311: 3305: 3303: 3299: 3298: 3296: 3295: 3294: 3293: 3287: 3282: 3272: 3271: 3270: 3264: 3262:Chlorpromazine 3253: 3251: 3249:Antipsychotics 3245: 3244: 3242: 3241: 3240: 3239: 3233: 3223: 3222: 3221: 3215: 3210: 3200: 3194: 3192: 3183: 3179: 3174: 3173: 3171: 3170: 3165: 3160: 3155: 3150: 3145: 3140: 3135: 3129: 3127: 3122: 3117: 3116: 3113: 3112: 3110: 3109: 3108: 3107: 3101: 3096: 3086: 3085: 3084: 3078: 3076:Chlorpromazine 3067: 3065: 3063:Antipsychotics 3059: 3058: 3056: 3055: 3054: 3053: 3047: 3037: 3036: 3035: 3029: 3024: 3014: 3013: 3012: 3007: 3002: 2991: 2989: 2983: 2982: 2980: 2979: 2974: 2969: 2964: 2959: 2954: 2949: 2944: 2939: 2937:Cyproheptadine 2934: 2928: 2926: 2924:Antihistamines 2917: 2913: 2908: 2907: 2905: 2904: 2899: 2894: 2889: 2884: 2881:sodium oxybate 2874: 2869: 2864: 2859: 2854: 2852:1,4-Butanediol 2848: 2846: 2842: 2837: 2836: 2833: 2832: 2830: 2829: 2828: 2827: 2825:Valerenic acid 2822: 2817: 2807: 2802: 2801: 2800: 2795: 2790: 2780: 2775: 2770: 2765: 2760: 2755: 2750: 2745: 2740: 2735: 2730: 2725: 2724: 2723: 2721:Sodium bromide 2718: 2713: 2702: 2697: 2691: 2689: 2685: 2684: 2682: 2681: 2676: 2671: 2666: 2661: 2656: 2651: 2646: 2641: 2636: 2630: 2628: 2626:Quinazolinones 2622: 2621: 2619: 2618: 2613: 2608: 2603: 2597: 2595: 2589: 2588: 2586: 2585: 2579: 2577: 2571: 2570: 2568: 2567: 2562: 2557: 2552: 2547: 2542: 2537: 2532: 2527: 2522: 2517: 2511: 2509: 2503: 2502: 2500: 2499: 2494: 2489: 2484: 2479: 2474: 2469: 2464: 2458: 2456: 2450: 2449: 2447: 2446: 2441: 2436: 2431: 2426: 2421: 2415: 2413: 2407: 2406: 2404: 2403: 2398: 2393: 2387: 2385: 2379: 2378: 2376: 2375: 2370: 2365: 2360: 2355: 2350: 2345: 2340: 2335: 2329: 2327: 2321: 2320: 2318: 2317: 2312: 2307: 2302: 2297: 2292: 2287: 2282: 2277: 2272: 2267: 2262: 2257: 2252: 2247: 2242: 2237: 2232: 2227: 2222: 2217: 2212: 2206: 2204: 2198: 2197: 2195: 2194: 2189: 2184: 2179: 2174: 2169: 2164: 2159: 2154: 2149: 2147:Propylbarbital 2144: 2139: 2134: 2129: 2124: 2119: 2114: 2109: 2104: 2099: 2094: 2089: 2084: 2079: 2074: 2069: 2063: 2061: 2055: 2054: 2052: 2051: 2046: 2044:Methylpentynol 2041: 2036: 2031: 2026: 2021: 2015: 2013: 2004: 2000: 1995: 1994: 1978: 1977: 1970: 1963: 1955: 1947: 1946: 1921: 1899: 1876: 1858: 1821: 1802: 1783: 1769: 1729: 1688: 1650: 1631: 1596: 1569: 1542: 1499: 1464: 1415: 1376: 1354:(2023-03-31). 1342: 1341: 1339: 1336: 1335: 1334: 1329: 1324: 1317: 1314: 1257:Shirley Knight 1210:'s 1973 novel 1208:Thomas Pynchon 1193:'s 1967 novel 1186: 1183: 1155: 1152: 1128: 1125: 1119: 1116: 1111: 1108: 1107: 1106: 1101: 1096: 1083: 1078: 1062: 1057: 1055:Methoxyflurane 1052: 1047: 1042: 1037: 1032: 1027: 1025:Chlorpromazine 1022: 1017: 992: 987: 974: 964:Antihistamines 961: 951:Antiepileptics 948: 918: 915: 863: 860: 859: 858: 853: 848: 843: 836: 833: 831: 828: 815: 812: 806:in mice of 212 802: 746:at individual 726: 714: 711: 663:amylobarbitone 654: 653: 642: 641: 639: 638: 635: 633: 630: 622: 621: 620: 617: 616: 614: 613: 610: 602: 601: 600: 597: 596: 594: 593: 585: 583: 575: 574: 568: 562: 561: 558: 552: 546: 540: 535: 529: 528: 524: 523: 513: 505: 504: 502: 501: 488: 486: 473: 472: 470: 469: 461: 459: 453: 452: 450: 449: 441: 439: 433: 432: 430: 429: 421: 419: 413: 412: 410: 409: 401: 399: 393: 392: 390: 389: 381: 379: 373: 372: 370: 369: 361: 359: 353: 352: 350: 349: 341: 339: 328: 327: 325: 324: 315: 313: 307: 306: 304: 303: 300: 292: 291: 290: 287: 286: 282: 281: 276: 270: 269: 266: 257: 256: 251: 245: 244: 237: 236: 234: 233: 230: 218: 202: 190: 178: 167: 153: 151: 145: 144: 140: 139: 137: 136: 123: 121: 115: 114: 103: 101:administration 95: 94: 92: 91: 73: 71: 65: 64: 57: 47: 46: 42: 41: 33: 32: 15: 9: 6: 4: 3: 2: 6243: 6232: 6229: 6227: 6224: 6222: 6219: 6217: 6214: 6212: 6209: 6208: 6206: 6193: 6192: 6188: 6184: 6181: 6175: 6169: 6166: 6164: 6161: 6159: 6156: 6154: 6151: 6148: 6147: 6143: 6139: 6135: 6134:isovaleramide 6131: 6127: 6124: 6122: 6119: 6116: 6112: 6109: 6106: 6102: 6098: 6094: 6091: 6089: 6086: 6084: 6081: 6079: 6076: 6074: 6071: 6069: 6066: 6064: 6061: 6059: 6056: 6054: 6051: 6049: 6046: 6044: 6041: 6039: 6036: 6034: 6031: 6028: 6024: 6020: 6016: 6012: 6009: 6007: 6004: 6002: 5999: 5997: 5994: 5992: 5989: 5987: 5984: 5982: 5979: 5976: 5972: 5971:niflumic acid 5968: 5964: 5960: 5957: 5955: 5952: 5950: 5947: 5945: 5942: 5940: 5937: 5934: 5930: 5926: 5922: 5918: 5915: 5913: 5910: 5908: 5905: 5903: 5900: 5898: 5897:Clomethiazole 5895: 5893: 5892:Chlormezanone 5890: 5888: 5885: 5883: 5882:Carbamazepine 5880: 5877: 5873: 5869: 5865: 5862: 5859: 5855: 5852: 5850: 5847: 5845: 5842: 5840: 5837: 5835: 5832: 5831: 5829: 5825: 5819: 5816: 5814: 5811: 5809: 5806: 5804: 5801: 5799: 5796: 5794: 5791: 5789: 5786: 5784: 5781: 5779: 5776: 5774: 5771: 5769: 5766: 5764: 5761: 5759: 5758:Nitrous oxide 5756: 5754: 5751: 5749: 5746: 5744: 5741: 5739: 5736: 5734: 5731: 5729: 5726: 5724: 5721: 5719: 5716: 5714: 5711: 5709: 5706: 5704: 5701: 5699: 5696: 5694: 5691: 5689: 5688:Diethyl ether 5686: 5684: 5681: 5679: 5676: 5674: 5671: 5669: 5666: 5664: 5661: 5659: 5656: 5654: 5651: 5649: 5646: 5644: 5641: 5639: 5636: 5634: 5631: 5629: 5626: 5624: 5621: 5619: 5616: 5614: 5611: 5609: 5606: 5605: 5603: 5601: 5597: 5593: 5587: 5584: 5582: 5579: 5577: 5574: 5572: 5569: 5567: 5564: 5562: 5559: 5557: 5554: 5552: 5549: 5547: 5544: 5542: 5539: 5538: 5536: 5534: 5530: 5524: 5521: 5519: 5516: 5514: 5511: 5509: 5506: 5505: 5503: 5501: 5497: 5491: 5490:Pyrithyldione 5488: 5486: 5483: 5481: 5478: 5476: 5473: 5472: 5470: 5468: 5464: 5458: 5455: 5453: 5450: 5448: 5445: 5444: 5442: 5440: 5436: 5430: 5427: 5425: 5422: 5420: 5417: 5415: 5412: 5410: 5407: 5405: 5402: 5400: 5397: 5395: 5392: 5390: 5387: 5385: 5382: 5380: 5377: 5375: 5372: 5370: 5367: 5365: 5362: 5360: 5357: 5355: 5352: 5350: 5347: 5345: 5342: 5340: 5337: 5335: 5332: 5330: 5327: 5325: 5322: 5320: 5317: 5315: 5312: 5310: 5307: 5305: 5302: 5300: 5297: 5295: 5292: 5290: 5287: 5285: 5281: 5278: 5277: 5274: 5271: 5269: 5266: 5264: 5261: 5259: 5256: 5254: 5251: 5249: 5246: 5244: 5241: 5239: 5235: 5234: 5230: 5229: 5226: 5223: 5221: 5218: 5216: 5213: 5211: 5208: 5206: 5202: 5201: 5197: 5196: 5193: 5190: 5188: 5185: 5183: 5180: 5178: 5175: 5173: 5170: 5168: 5164: 5163: 5159: 5158: 5156: 5154: 5150: 5144: 5141: 5139: 5136: 5134: 5131: 5129: 5126: 5124: 5121: 5119: 5116: 5114: 5111: 5109: 5106: 5104: 5101: 5099: 5096: 5094: 5091: 5089: 5086: 5084: 5081: 5079: 5076: 5074: 5071: 5069: 5066: 5064: 5061: 5059: 5056: 5054: 5051: 5049: 5046: 5044: 5041: 5039: 5036: 5034: 5031: 5029: 5026: 5024: 5021: 5019: 5015: 5013: 5010: 5008: 5005: 5003: 5000: 4998: 4995: 4993: 4990: 4988: 4985: 4983: 4980: 4979: 4977: 4975: 4971: 4965: 4962: 4960: 4957: 4955: 4952: 4950: 4947: 4945: 4942: 4940: 4937: 4936: 4934: 4932: 4928: 4922: 4919: 4917: 4914: 4912: 4909: 4907: 4904: 4902: 4899: 4897: 4894: 4892: 4889: 4887: 4884: 4882: 4879: 4877: 4874: 4872: 4869: 4867: 4864: 4862: 4859: 4857: 4854: 4852: 4849: 4848: 4846: 4843: 4839: 4833: 4830: 4828: 4825: 4823: 4820: 4819: 4817: 4815: 4811: 4805: 4802: 4799: 4795: 4792: 4790: 4787: 4785: 4782: 4780: 4777: 4775: 4772: 4770: 4767: 4765: 4762: 4760: 4757: 4755: 4752: 4750: 4747: 4745: 4742: 4740: 4737: 4735: 4732: 4731: 4729: 4727: 4723: 4717: 4714: 4712: 4709: 4707: 4704: 4702: 4699: 4697: 4696:Phenprobamate 4694: 4692: 4689: 4687: 4684: 4682: 4679: 4677: 4674: 4672: 4669: 4667: 4664: 4662: 4661:Hexapropymate 4659: 4657: 4654: 4652: 4649: 4647: 4644: 4642: 4639: 4637: 4636:Difebarbamate 4634: 4632: 4629: 4627: 4624: 4622: 4619: 4617: 4614: 4613: 4611: 4609: 4605: 4599: 4596: 4594: 4591: 4589: 4586: 4584: 4581: 4579: 4576: 4574: 4571: 4569: 4566: 4564: 4561: 4559: 4556: 4554: 4551: 4549: 4546: 4544: 4541: 4539: 4536: 4534: 4531: 4529: 4526: 4524: 4521: 4519: 4516: 4514: 4511: 4509: 4506: 4504: 4501: 4499: 4496: 4494: 4491: 4489: 4486: 4484: 4481: 4479: 4476: 4474: 4471: 4469: 4466: 4464: 4461: 4459: 4456: 4454: 4451: 4449: 4448:Nortetrazepam 4446: 4444: 4441: 4439: 4436: 4434: 4431: 4429: 4426: 4424: 4421: 4419: 4416: 4414: 4411: 4409: 4406: 4404: 4401: 4399: 4396: 4394: 4391: 4389: 4386: 4384: 4381: 4379: 4376: 4374: 4371: 4369: 4366: 4364: 4361: 4359: 4356: 4354: 4351: 4349: 4346: 4344: 4341: 4339: 4336: 4334: 4331: 4329: 4326: 4324: 4321: 4319: 4316: 4314: 4311: 4309: 4308:Flutoprazepam 4306: 4304: 4301: 4299: 4296: 4294: 4291: 4289: 4288:Flunitrazolam 4286: 4284: 4283:Flunitrazepam 4281: 4279: 4276: 4274: 4273:Flubromazolam 4271: 4269: 4268:Flubromazepam 4266: 4264: 4261: 4259: 4256: 4254: 4251: 4249: 4246: 4244: 4241: 4239: 4236: 4234: 4231: 4229: 4226: 4224: 4221: 4219: 4216: 4214: 4211: 4209: 4206: 4204: 4201: 4199: 4196: 4194: 4191: 4189: 4186: 4184: 4181: 4179: 4176: 4174: 4171: 4169: 4168:Cloniprazepam 4166: 4164: 4161: 4159: 4156: 4154: 4151: 4149: 4146: 4144: 4141: 4139: 4136: 4134: 4131: 4129: 4126: 4124: 4121: 4119: 4116: 4114: 4111: 4109: 4106: 4104: 4101: 4099: 4096: 4094: 4091: 4089: 4086: 4084: 4081: 4079: 4076: 4074: 4071: 4069: 4066: 4064: 4061: 4059: 4058:2-Oxoquazepam 4056: 4055: 4053: 4051: 4047: 4041: 4038: 4036: 4033: 4031: 4028: 4026: 4023: 4021: 4018: 4016: 4013: 4011: 4008: 4006: 4003: 4001: 4000:Thialbarbital 3998: 3996: 3995:Tetrabarbital 3993: 3991: 3988: 3986: 3983: 3981: 3980:Spirobarbital 3978: 3976: 3973: 3971: 3968: 3966: 3963: 3961: 3960:Proxibarbital 3958: 3956: 3953: 3951: 3950:Propallylonal 3948: 3946: 3943: 3941: 3938: 3936: 3933: 3931: 3930:Phenobarbital 3928: 3926: 3923: 3921: 3920:Pentobarbital 3918: 3916: 3913: 3911: 3910:Narcobarbital 3908: 3906: 3903: 3901: 3898: 3896: 3893: 3891: 3888: 3886: 3883: 3881: 3878: 3876: 3875:Heptobarbital 3873: 3871: 3868: 3866: 3863: 3861: 3858: 3856: 3853: 3851: 3848: 3846: 3845:Difebarbamate 3843: 3841: 3838: 3836: 3835:Cyclobarbital 3833: 3831: 3828: 3826: 3823: 3821: 3818: 3816: 3813: 3811: 3808: 3806: 3803: 3801: 3798: 3796: 3793: 3791: 3788: 3786: 3783: 3781: 3780:Benzobarbital 3778: 3776: 3773: 3771: 3768: 3766: 3763: 3761: 3758: 3756: 3753: 3751: 3748: 3746: 3743: 3742: 3740: 3738: 3734: 3728: 3725: 3723: 3720: 3718: 3715: 3713: 3710: 3708: 3706: 3702: 3700: 3698: 3694: 3692: 3689: 3687: 3684: 3682: 3679: 3677: 3674: 3672: 3669: 3667: 3664: 3662: 3659: 3657: 3654: 3652: 3651:Ethchlorvynol 3649: 3646: 3642: 3639: 3637: 3634: 3632: 3629: 3627: 3624: 3622: 3619: 3618: 3616: 3614: 3610: 3606: 3593: 3588: 3586: 3581: 3579: 3574: 3573: 3570: 3558: 3555: 3553: 3550: 3548: 3545: 3543: 3540: 3538: 3535: 3532: 3528: 3525: 3523: 3520: 3516: 3515:Methocarbamol 3513: 3511: 3508: 3506: 3505:Mephenoxalone 3503: 3501: 3498: 3496: 3495:Chlorphenesin 3493: 3492: 3491: 3487: 3484: 3482: 3479: 3477: 3474: 3472: 3469: 3465: 3464:Phenaglycodol 3462: 3460: 3457: 3455: 3452: 3451: 3450: 3447: 3443: 3440: 3439: 3438: 3435: 3434: 3432: 3428: 3422: 3419: 3417: 3414: 3412: 3409: 3407: 3404: 3402: 3399: 3398: 3396: 3394: 3381: 3375: 3372: 3370: 3367: 3365: 3362: 3361: 3359: 3357: 3353: 3347: 3344: 3342: 3339: 3337: 3334: 3332: 3329: 3328: 3326: 3324: 3320: 3310: 3307: 3306: 3304: 3300: 3291: 3288: 3286: 3283: 3281: 3278: 3277: 3276: 3273: 3268: 3265: 3263: 3260: 3259: 3258: 3255: 3254: 3252: 3250: 3246: 3237: 3234: 3232: 3229: 3228: 3227: 3224: 3219: 3216: 3214: 3211: 3209: 3208:Amitriptyline 3206: 3205: 3204: 3201: 3199: 3196: 3195: 3193: 3191: 3187: 3184: 3182: 3175: 3169: 3166: 3164: 3161: 3159: 3156: 3154: 3151: 3149: 3146: 3144: 3141: 3139: 3136: 3134: 3131: 3130: 3128: 3126: 3118: 3105: 3102: 3100: 3097: 3095: 3092: 3091: 3090: 3087: 3082: 3079: 3077: 3074: 3073: 3072: 3069: 3068: 3066: 3064: 3060: 3051: 3048: 3046: 3043: 3042: 3041: 3038: 3033: 3030: 3028: 3025: 3023: 3022:Amitriptyline 3020: 3019: 3018: 3015: 3011: 3008: 3006: 3003: 3001: 2998: 2997: 2996: 2993: 2992: 2990: 2988: 2984: 2978: 2975: 2973: 2970: 2968: 2965: 2963: 2960: 2958: 2957:Methapyrilene 2955: 2953: 2950: 2948: 2945: 2943: 2940: 2938: 2935: 2933: 2930: 2929: 2927: 2925: 2921: 2918: 2916: 2909: 2903: 2900: 2898: 2895: 2893: 2890: 2888: 2885: 2882: 2878: 2875: 2873: 2870: 2868: 2865: 2863: 2862:Aceburic acid 2860: 2858: 2855: 2853: 2850: 2849: 2847: 2845: 2838: 2826: 2823: 2821: 2818: 2816: 2815:Isovaleramide 2813: 2812: 2811: 2810:Sesquiterpene 2808: 2806: 2803: 2799: 2796: 2794: 2791: 2789: 2786: 2785: 2784: 2781: 2779: 2776: 2774: 2771: 2769: 2766: 2764: 2761: 2759: 2756: 2754: 2751: 2749: 2748:Clomethiazole 2746: 2744: 2741: 2739: 2736: 2734: 2731: 2729: 2726: 2722: 2719: 2717: 2714: 2712: 2709: 2708: 2706: 2703: 2701: 2698: 2696: 2693: 2692: 2690: 2686: 2680: 2677: 2675: 2672: 2670: 2667: 2665: 2662: 2660: 2657: 2655: 2652: 2650: 2647: 2645: 2642: 2640: 2637: 2635: 2632: 2631: 2629: 2627: 2623: 2617: 2614: 2612: 2611:Pyrithyldione 2609: 2607: 2604: 2602: 2599: 2598: 2596: 2594: 2590: 2584: 2581: 2580: 2578: 2576: 2572: 2566: 2563: 2561: 2558: 2556: 2553: 2551: 2548: 2546: 2543: 2541: 2538: 2536: 2533: 2531: 2528: 2526: 2523: 2521: 2518: 2516: 2513: 2512: 2510: 2508: 2504: 2498: 2495: 2493: 2490: 2488: 2485: 2483: 2480: 2478: 2475: 2473: 2470: 2468: 2465: 2463: 2460: 2459: 2457: 2455: 2451: 2445: 2442: 2440: 2437: 2435: 2432: 2430: 2427: 2425: 2422: 2420: 2417: 2416: 2414: 2412: 2408: 2402: 2399: 2397: 2394: 2392: 2389: 2388: 2386: 2384: 2380: 2374: 2371: 2369: 2366: 2364: 2363:Phenprobamate 2361: 2359: 2358:Methocarbamol 2356: 2354: 2351: 2349: 2348:Hexapropymate 2346: 2344: 2341: 2339: 2336: 2334: 2331: 2330: 2328: 2326: 2322: 2316: 2313: 2311: 2308: 2306: 2303: 2301: 2298: 2296: 2293: 2291: 2288: 2286: 2283: 2281: 2278: 2276: 2273: 2271: 2268: 2266: 2265:Flutoprazepam 2263: 2261: 2258: 2256: 2253: 2251: 2250:Flunitrazepam 2248: 2246: 2245:Flunitrazolam 2243: 2241: 2240:Flubromazolam 2238: 2236: 2233: 2231: 2228: 2226: 2223: 2221: 2218: 2216: 2213: 2211: 2208: 2207: 2205: 2203: 2199: 2193: 2190: 2188: 2185: 2183: 2180: 2178: 2175: 2173: 2170: 2168: 2165: 2163: 2160: 2158: 2155: 2153: 2150: 2148: 2145: 2143: 2142:Phenobarbital 2140: 2138: 2135: 2133: 2132:Pentobarbital 2130: 2128: 2127:Narcobarbital 2125: 2123: 2120: 2118: 2117:Mephobarbital 2115: 2113: 2110: 2108: 2105: 2103: 2100: 2098: 2097:Cyclobarbital 2095: 2093: 2090: 2088: 2085: 2083: 2080: 2078: 2075: 2073: 2070: 2068: 2065: 2064: 2062: 2060: 2056: 2050: 2047: 2045: 2042: 2040: 2039:Ethchlorvynol 2037: 2035: 2032: 2030: 2027: 2025: 2022: 2020: 2017: 2016: 2014: 2012: 2008: 2005: 2003: 1996: 1991: 1987: 1983: 1976: 1971: 1969: 1964: 1962: 1957: 1956: 1953: 1935: 1931: 1925: 1911: 1910: 1903: 1889: 1888: 1880: 1872: 1868: 1862: 1846: 1842: 1838: 1837: 1832: 1825: 1812: 1806: 1793: 1787: 1779: 1773: 1766: 1764: 1760: 1747: 1743: 1739: 1733: 1725: 1721: 1716: 1711: 1707: 1703: 1699: 1692: 1681: 1677: 1673: 1669: 1666:(5): 423–36. 1665: 1661: 1654: 1646: 1642: 1635: 1627: 1623: 1619: 1615: 1611: 1607: 1600: 1592: 1588: 1584: 1580: 1573: 1565: 1561: 1558:(1): 118–21. 1557: 1553: 1546: 1538: 1534: 1530: 1526: 1522: 1518: 1515:(3): 385–90. 1514: 1510: 1503: 1495: 1491: 1487: 1483: 1480:(5): 224–31. 1479: 1475: 1468: 1460: 1456: 1451: 1446: 1442: 1438: 1435:(4): 485–94. 1434: 1430: 1426: 1419: 1411: 1407: 1403: 1399: 1395: 1391: 1387: 1380: 1365: 1361: 1357: 1353: 1347: 1343: 1333: 1330: 1328: 1325: 1323: 1320: 1319: 1313: 1311: 1310: 1305: 1300: 1298: 1297: 1291: 1289: 1288: 1282: 1279: 1278: 1272: 1270: 1266: 1262: 1258: 1254: 1250: 1249: 1245:In 2001, the 1243: 1241: 1237: 1236: 1230: 1228: 1224: 1223: 1217: 1215: 1214: 1209: 1204: 1202: 1198: 1197: 1192: 1182: 1178: 1176: 1171: 1168: 1167:Robert Walker 1163: 1161: 1151: 1149: 1145: 1141: 1136: 1134: 1124: 1115: 1105: 1102: 1100: 1097: 1095: 1091: 1087: 1084: 1082: 1079: 1077: 1073: 1069: 1066: 1063: 1061: 1060:Metronidazole 1058: 1056: 1053: 1051: 1048: 1046: 1043: 1041: 1038: 1036: 1033: 1031: 1028: 1026: 1023: 1021: 1018: 1016: 1012: 1008: 1004: 1000: 996: 993: 991: 988: 986: 982: 978: 975: 973: 969: 965: 962: 960: 959:carbamazepine 956: 955:phenobarbital 952: 949: 947: 943: 939: 936: 935: 934: 928: 923: 914: 911: 907: 903: 899: 894: 892: 888: 885: 880: 878: 873: 869: 857: 854: 852: 849: 847: 844: 842: 839: 838: 827: 825: 821: 820:hydroxylation 811: 805: 797: 795: 791: 787: 786:phenobarbital 783: 782:pentobarbital 779: 778: 773: 768: 766: 761: 759: 756: 753: 749: 745: 741: 738: 734: 730: 722: 721: 710: 707: 702: 699: 695: 691: 686: 684: 680: 676: 672: 668: 667:sodium amytal 664: 660: 650: 643: 634: 629: 628: 625: 618: 609: 608: 605: 598: 591: 587: 586: 584: 581: 576: 569: 567: 563: 536: 534: 530: 525: 521: 517: 514: 512: 510:ECHA InfoCard 506: 498: 494: 493:DTXSID9020081 490: 489: 487: 478: 474: 467: 463: 462: 460: 458: 454: 447: 443: 442: 440: 438: 434: 427: 423: 422: 420: 418: 414: 407: 403: 402: 400: 398: 394: 387: 383: 382: 380: 378: 374: 367: 363: 362: 360: 358: 354: 347: 343: 342: 340: 333: 329: 321: 317: 316: 314: 312: 308: 299: 298: 295: 288: 283: 280: 277: 275: 271: 267: 265: 258: 255: 252: 250: 246: 242: 238: 231: 229: 219: 217: 213: 203: 201: 191: 188: 179: 177: 168: 165: 155: 154: 152: 150: 146: 141: 133: 128: 125: 124: 122: 120: 116: 112: 108: 104: 102: 96: 89: 85: 75: 74: 72: 70: 66: 62: 58: 56: 52: 48: 45:Clinical data 43: 39: 34: 30: 25: 6216:Barbiturates 6179: 6178: 6149: 6006:Lavender oil 5748:Nitric oxide 5668:Cryofluorane 5613:Acetophenone 5571:Methaqualone 5566:Mecloqualone 5561:Mebroqualone 5551:Diproqualone 5546:Cloroqualone 5475:Glutethimide 5279: 5231: 5198: 5160: 5133:Testosterone 5098:Progesterone 5063:Hydroxydione 5012:Androsterone 4939:Acecarbromal 4844:constituents 4631:Cyclarbamate 4621:Carisoprodol 4393:Metaclazepam 4388:Menitrazepam 4378:Meclonazepam 4373:Lormetazepam 4303:Flutemazepam 4128:Ciclotizolam 4118:Carburazepam 4010:Thiobarbital 3970:Secobarbital 3935:Phetharbital 3915:Nealbarbital 3900:Methohexital 3885:Hexobarbital 3820:Butallylonal 3815:Butobarbital 3770:Barbexaclone 3765:Aprobarbital 3759: 3750:Allobarbital 3737:Barbiturates 3704: 3696: 3686:Petrichloral 3557:Valnoctamide 3459:Metaglycodol 3454:Fenpentadiol 3364:Daridorexant 3267:Thioridazine 3218:Trimipramine 3153:Medetomidine 3081:Thioridazine 3032:Trimipramine 2977:Propiomazine 2972:Promethazine 2778:Petrichloral 2763:Kavalactones 2695:Acetophenone 2664:Methaqualone 2659:Mecloqualone 2654:Mebroqualone 2644:Diproqualone 2639:Cloroqualone 2601:Glutethimide 2497:Progesterone 2487:Hydroxydione 2419:Acecarbromal 2333:Carisoprodol 2275:Lormetazepam 2260:Flutemazepam 2162:Secobarbital 2122:Methohexital 2112:Hexobarbital 2092:Butobarbital 2087:Butabarbital 2077:Aprobarbital 2071: 2067:Allobarbital 2059:Barbiturates 1938:. Retrieved 1936:. 2018-11-18 1933: 1924: 1914:, retrieved 1908: 1902: 1892:, retrieved 1886: 1879: 1870: 1861: 1849:. Retrieved 1834: 1824: 1805: 1786: 1772: 1762: 1758: 1756: 1750:. Retrieved 1741: 1732: 1708:(5): 195–7. 1705: 1701: 1691: 1663: 1659: 1653: 1644: 1640: 1634: 1609: 1605: 1599: 1585:(1): 45–53. 1582: 1578: 1572: 1555: 1551: 1545: 1512: 1508: 1502: 1477: 1473: 1467: 1432: 1428: 1418: 1393: 1389: 1379: 1368:. Retrieved 1346: 1307: 1301: 1294: 1292: 1285: 1283: 1275: 1273: 1261:George Huang 1246: 1244: 1233: 1231: 1220: 1219:In the 1975 1218: 1211: 1205: 1194: 1191:Len Deighton 1188: 1179: 1175:Tony Hancock 1172: 1164: 1157: 1140:malonic acid 1137: 1130: 1121: 1113: 1110:Interactions 1099:Theophylline 932: 902:World War II 895: 881: 877:false memory 865: 817: 810:mg/kg s.c. 798: 793: 775: 769: 762: 755:postsynaptic 718: 716: 713:Pharmacology 706:secobarbital 703: 687: 666: 662: 658: 657: 646:   466:ChEMBL267894 261:Elimination 216:Schedule III 149:Legal status 143:Legal status 69:License data 6088:Stiripentol 6083:Seproxetine 6053:Niacinamide 6033:Loreclezole 5854:Avermectins 5818:Vinyl ether 5788:Sevoflurane 5768:Paraldehyde 5718:Halopropane 5541:Afloqualone 5523:Tracazolate 5518:ICI-190,622 5508:Cartazolate 5485:Piperidione 5480:Methyprylon 5447:Fospropofol 5369:Pipequaline 5177:Pazinaclone 5167:Eszopiclone 5023:Cholesterol 5007:Androstenol 4931:Monoureides 4911:Methysticin 4711:Tetrabamate 4691:Pentabamate 4681:Meprobamate 4651:Febarbamate 4616:Carisbamate 4568:Triflubazam 4558:Tolufazepam 4518:Rilmazafone 4513:Remimazolam 4488:Proflazepam 4473:Pivoxazepam 4433:Nitrazepate 4423:Nimetazepam 4358:Lopirazepam 4328:Haloxazolam 4278:Fludiazepam 4223:Doxefazepam 4198:Delorazepam 4178:Clotiazepam 4173:Clorazepate 4138:Cinolazepam 4035:Vinbarbital 3990:Tetrabamate 3945:Probarbital 3925:Phenallymal 3890:Metharbital 3865:Febarbamate 3760:Amobarbital 3661:Isopropanol 3631:Chloralodol 3542:Scopolamine 3486:Guaifenesin 3481:Fenadiazole 3437:Cannabidiol 3411:Mirogabalin 3369:Lemborexant 3346:Tasimelteon 3331:Agomelatine 3290:Risperidone 3236:Mirtazapine 3125:-Adrenergic 3104:Risperidone 3050:Mirtazapine 3000:Etoperidone 2967:Pheniramine 2952:Hydroxyzine 2773:Paraldehyde 2768:Loreclezole 2634:Afloqualone 2616:Piperidione 2606:Methyprylon 2535:Pazinaclone 2515:Eszopiclone 2477:Alphaxolone 2472:Alphadolone 2411:Monoureides 2353:Meprobamate 2290:Nitemazepam 2285:Nimetazepam 2230:Doxefazepam 2215:Cinolazepam 2187:Vinbarbital 2152:Proxibarbal 2137:Phenallymal 2072:Amobarbital 2024:Chloralodol 1851:December 4, 1660:Social Work 1277:Sealab 2021 1050:Doxycycline 1045:Doxorubicin 1035:Ciclosporin 985:propranolol 906:shell shock 868:truth serum 830:Indications 794:amobarbital 765:reperfusion 744:conductance 671:barbiturate 659:Amobarbital 573: g·mol 516:100.000.300 285:Identifiers 212:Schedule II 176:Schedule IV 88:Amobarbital 21:Amobarbital 16:Barbiturate 6205:Categories 6121:Topiramate 6111:Terpenoids 6068:Propanidid 6058:Org 25,435 5986:Flupirtine 5981:Fluoxetine 5887:Chloralose 5858:ivermectin 5763:Norflurane 5728:Isoflurane 5673:Desflurane 5663:Chloroform 5623:Aliflurane 5556:Etaqualone 5384:SB-205,384 5314:CP-615,003 5309:CL-218,872 5263:Panadiplon 5253:Lorediplon 5182:Suproclone 5143:Zuranolone 5103:Renanolone 5088:Posovolone 5068:Minaxolone 5058:Ganaxolone 4997:Alfaxalone 4992:Alfadolone 4982:Acebrochol 4949:Bromisoval 4827:Metomidate 4814:Imidazoles 4774:Hispidulin 4726:Flavonoids 4686:Nisobamate 4676:Mebutamate 4646:Ethinamate 4641:Emylcamate 4608:Carbamates 4578:Tuclazepam 4553:Tetrazepam 4508:Reclazepam 4483:Premazepam 4463:Phenazepam 4443:Nordazepam 4438:Nitrazolam 4428:Nitrazepam 4408:Motrazepam 4363:Loprazolam 4353:Lofendazam 4338:Imidazenil 4298:Flutazolam 4293:Flurazepam 4263:Fletazepam 4218:Dimdazenil 4213:Diclazepam 4193:Cyprazepam 4183:Cloxazolam 4163:Clonazolam 4158:Clonazepam 4148:Climazolam 4108:Brotizolam 4103:Bromazolam 4098:Bromazepam 4093:Bretazenil 4088:Bentazepam 4078:Arfendazam 4073:Alprazolam 4068:Adinazolam 4040:Vinylbital 4020:Thiopental 3895:Methitural 3810:Buthalital 3805:Butalbital 3656:Isobutanol 3510:Metaxalone 3500:Mephenesin 3421:Pregabalin 3401:Gabapentin 3374:Suvorexant 3309:Niaprazine 3285:Quetiapine 3280:Olanzapine 3163:Tizanidine 3158:Romifidine 3148:Lofexidine 3138:Detomidine 3099:Quetiapine 3094:Olanzapine 3005:Nefazodone 2947:Doxylamine 2932:Captodiame 2743:Chloralose 2707:compounds 2649:Etaqualone 2545:Suproclone 2525:Lirequinil 2492:Minaxolone 2482:Eltanolone 2462:Acebrochol 2429:Bromisoval 2396:Metomidate 2383:Imidazoles 2343:Ethinamate 2338:Emylcamate 2325:Carbamates 2300:Nitrazolam 2295:Nitrazepam 2270:Loprazolam 2255:Flurazepam 2225:Clonazolam 2220:Climazolam 2210:Brotizolam 2192:Vinylbital 2177:Thiopental 1940:2024-01-11 1916:2024-01-11 1894:2024-01-11 1836:60 Minutes 1759:blue 88's. 1752:2017-08-24 1647:: 693–696. 1612:: 309–14. 1370:2023-08-16 1327:Depressant 1269:suggestion 1090:prednisone 1088:, such as 1070:, such as 1068:analgesics 1011:alprazolam 1007:nitrazepam 1003:clonazepam 997:, such as 979:, such as 972:clemastine 968:doxylamine 966:, such as 953:, such as 940:, such as 910:front-line 814:Metabolism 799:It has an 752:inhibitory 578:3D model ( 566:Molar mass 446:CHEBI:2673 406:GWH6IJ239E 377:ChemSpider 311:CAS Number 294:IUPAC name 268:8–42 hours 249:Metabolism 187:Anlage III 6211:Hypnotics 6180:See also: 6142:valerenol 6063:Phenytoin 6043:Monastrol 6001:Lanthanum 5996:KRM-II-81 5959:Fenamates 5954:Etifoxine 5949:Etazepine 5944:Efavirenz 5902:Darigabat 5798:Teflurane 5783:Roflurane 5778:Propylene 5723:Halothane 5708:Fluroxene 5693:Enflurane 5596:Volatiles 5513:Etazolate 5424:Viqualine 5379:RWJ-51204 5344:L-838,417 5334:Imepitoin 5304:CGS-20625 5299:CGS-13767 5284:Adipiplon 5258:Ocinaplon 5220:Saripidem 5215:Necopidem 5192:Zopiclone 5187:Suriclone 5172:Pagoclone 5078:ORG-21465 5073:ORG-20599 4964:Ectylurea 4954:Carbromal 4832:Propoxate 4822:Etomidate 4749:Baicalein 4706:Styramate 4701:Procymate 4671:Lorbamate 4656:Felbamate 4626:Clocental 4598:Zomebazam 4593:Zolazepam 4588:Zapizolam 4583:Uldazepam 4563:Triazolam 4548:Temazepam 4543:Sulazepam 4533:Ro48-8684 4528:Ro48-6791 4523:Ripazepam 4493:Pyrazolam 4468:Pinazepam 4418:Nifoxipam 4403:Midazolam 4398:Mexazolam 4383:Medazepam 4368:Lorazepam 4348:Ketazolam 4343:Irazepine 4333:Iclazepam 4323:Halazepam 4318:Gidazepam 4313:Fosazepam 4233:Estazolam 4228:Elfazepam 4203:Demoxepam 4133:Cinazepam 4113:Camazepam 4083:Avizafone 4005:Thiamylal 3940:Primidone 3870:Heptabarb 3860:Eterobarb 3825:Carbubarb 3722:Triclofos 3621:Brometone 3547:Trazodone 3488:-related 3341:Ramelteon 3336:Melatonin 3323:Melatonin 3231:Mianserin 3198:Trazodone 3133:Clonidine 3045:Mianserin 3010:Trazodone 2962:Perlapine 2805:Triclofos 2758:Gaboxadol 2565:Zopiclone 2550:Suriclone 2540:Saripidem 2530:Necopidem 2444:Ectylurea 2439:Carbromal 2401:Propoxate 2391:Etomidate 2368:Procymate 2315:Triazolam 2310:Temazepam 2280:Midazolam 2235:Estazolam 2172:Thiamylal 2107:Heptabarb 1986:sedatives 1982:Hypnotics 1410:1079-2082 1396:(2): 84. 1304:Dan Brown 1235:True Lies 1225:episode " 1127:Chemistry 1094:cortisone 1076:oxycodone 1040:Digitoxin 1015:lorazepam 942:verapamil 884:catatonic 856:Wada test 729:receptors 274:Excretion 263:half-life 99:Routes of 55:Drugs.com 6168:TCS-1205 6163:TCS-1105 6153:α-Pinene 6126:Valerian 6101:tetronal 6078:Safranal 6027:obovatol 6023:magnolol 6019:honokiol 5849:Alogabat 5844:AA-29504 5793:Synthane 5753:Nitrogen 5733:Kerosine 5713:Gasoline 5703:Ethylene 5643:Centalun 5638:Butylene 5452:Propofol 5414:U-89843A 5394:TGSC01AA 5364:NS-11394 5329:GBLD-345 5294:CGS-9896 5289:CGS-8216 5273:Zaleplon 5268:Taniplon 5248:Indiplon 5243:Fasiplon 5238:Divaplon 5225:Zolpidem 5128:SAGE-872 5123:SAGE-689 5118:SAGE-516 5113:SAGE-324 5108:SAGE-105 5016:Certain 4959:Capuride 4921:Yangonin 4798:baicalin 4794:Skullcap 4784:Luteolin 4759:Catechin 4754:Baicalin 4744:Apigenin 4716:Tybamate 4503:Quazepam 4498:QH-II-66 4478:Prazepam 4458:Oxazolam 4453:Oxazepam 4253:Etizolam 4208:Diazepam 4188:CP-1414S 4153:Clobazam 4143:Clazolam 4030:Valofane 3985:Talbutal 3975:Sigmodal 3880:Hexethal 3775:Barbital 3755:Alphenal 3745:(-)-DMBB 3691:Propanol 3681:Pentanol 3671:Methanol 3613:Alcohols 3531:morphine 3522:Midaflur 3442:Cannabis 3416:Phenibut 3168:Xylazine 2897:Phenibut 2867:Baclofen 2793:Tetronal 2728:Centalun 2583:Propofol 2560:Zolpidem 2555:Zaleplon 2520:Indiplon 2434:Capuride 2373:Tybamate 2305:Quazepam 2167:Talbutal 2082:Barbital 2011:Alcohols 1845:Archived 1841:CBS News 1763:blue 88s 1746:Archived 1537:29934652 1494:19375683 1459:15381635 1364:Archived 1316:See also 1118:Overdose 1104:Warfarin 1086:Steroids 1072:morphine 1065:Narcotic 999:diazepam 981:atenolol 891:caffeine 851:Insomnia 846:Epilepsy 835:Approved 790:barbital 774:binding 758:currents 720:in vitro 679:hypnotic 675:sedative 649:(verify) 357:DrugBank 214: / 164:Class B1 119:ATC code 113:, Rectal 6115:borneol 6113:(e.g., 6105:trional 6095:(e.g., 6013:(e.g., 6011:Lignans 5961:(e.g., 5919:(e.g., 5864:Bromide 5856:(e.g., 5839:α-EMTBL 5803:Toluene 5773:Propane 5648:Chloral 5628:Benzene 5608:Acetone 5439:Phenols 5429:Y-23684 5419:U-90042 5404:TPA-023 5389:SX-3228 5374:ROD-188 5359:NS-2710 5354:NS-2664 5339:JM-1232 5324:ELB-139 5319:CTP-354 5205:Alpidem 4804:Wogonin 4779:Linarin 4258:FG-8205 3965:Reposal 3666:Menthol 3626:Butanol 3529:(e.g., 3527:Opioids 3476:Evoxine 3213:Doxepin 3027:Doxepin 2902:Tolibut 2798:Trional 2705:Bromide 2575:Phenols 2157:Reposal 1744:. PBS. 1724:1489761 1715:1188455 1680:9739631 1626:3437019 1564:5855308 1529:2906155 1450:1575418 1322:Blue 88 1265:BD Wong 1222:Columbo 1081:Quinine 990:Ethanol 946:digoxin 900:during 841:Anxiety 777:in vivo 740:neurons 683:Germany 571:226.276 533:Formula 366:DB01351 332:PubChem 320:57-43-2 254:Hepatic 200:Class B 185:: 174:: 135:) 129: ( 127:N05CA02 86::  6048:Niacin 5633:Butane 5586:SL-164 5457:Thymol 5399:TP-003 5280:Others 5083:P1-185 5043:5β-DHP 5038:5α-DHP 5033:3α-DHP 4881:Kavain 4789:Rc-OMe 3430:Others 3356:Orexin 3302:Others 3292:, etc. 3269:, etc. 3238:, etc. 3220:, etc. 3106:, etc. 3083:, etc. 3052:, etc. 3034:, etc. 2688:Others 2679:SL-164 1817:  1798:  1722:  1712:  1678:  1624:  1591:684279 1589:  1562:  1535:  1527:  1492:  1457:  1447:  1408:  1352:Anvisa 1332:Tuinal 887:mutism 808:  717:In an 604:SMILES 457:ChEMBL 426:D00555 226: 210: 198: 162: 105:Oral, 81:  5907:DEABL 5600:gases 5409:TP-13 5138:THDOC 5028:DHDOC 3552:UMB68 2872:GABOB 1533:S2CID 1338:Notes 1013:, or 624:InChI 580:JSmol 437:ChEBI 279:Renal 5210:DS-1 4842:Kava 4769:EGCG 3705:tert 3697:tert 3600:GABA 3392:VDCC 3178:5-HT 2841:GABA 2019:2M2B 1999:GABA 1990:N05C 1853:2005 1720:PMID 1676:PMID 1622:PMID 1587:PMID 1560:PMID 1525:PMID 1490:PMID 1455:PMID 1406:ISSN 1144:urea 1092:and 1074:and 983:and 970:and 944:and 927:vial 788:and 725:GABA 417:KEGG 397:UNII 386:2079 346:2164 243:data 51:AHFS 5939:DS2 5048:DHT 4764:EGC 2892:GVL 2887:GBL 2877:GHB 1710:PMC 1668:doi 1614:doi 1610:422 1556:150 1517:doi 1482:doi 1478:153 1445:PMC 1437:doi 1433:143 1398:doi 1306:'s 1206:In 1201:LSD 1189:In 1150:). 957:or 665:or 482:EPA 336:CID 132:WHO 84:FDA 6207:: 6189:• 6185:• 6140:, 6136:, 6132:, 6103:, 6099:, 6025:, 6021:, 6017:, 5973:, 5969:, 5965:, 5931:, 5927:, 5923:, 5874:, 5870:, 5282:: 5236:: 5203:: 5165:: 3180:2A 1932:. 1869:. 1843:. 1839:. 1833:. 1755:. 1740:. 1718:. 1706:17 1704:. 1700:. 1674:. 1664:43 1662:. 1645:29 1643:. 1620:. 1608:. 1583:21 1581:. 1554:. 1531:. 1523:. 1513:96 1511:. 1488:. 1476:. 1453:. 1443:. 1431:. 1427:. 1404:. 1394:22 1392:. 1388:. 1009:, 1005:, 1001:, 925:A 803:50 801:LD 767:. 760:. 547:18 541:11 222:UN 206:US 194:UK 182:DE 171:CA 158:BR 111:IV 109:, 107:IM 78:US 6144:) 6117:) 6107:) 6029:) 5977:) 5935:) 5878:) 5860:) 5598:/ 4800:) 3647:) 3643:( 3603:A 3591:e 3584:t 3577:v 3533:) 3389:δ 3387:2 3385:α 3123:2 3121:α 2914:1 2912:H 2883:) 2879:( 2843:B 2001:A 1992:) 1988:( 1984:/ 1974:e 1967:t 1960:v 1943:. 1873:. 1855:. 1780:. 1726:. 1682:. 1670:: 1628:. 1616:: 1593:. 1566:. 1539:. 1519:: 1496:. 1484:: 1461:. 1439:: 1412:. 1400:: 1373:. 1263:( 875:" 727:A 677:- 582:) 559:3 556:O 553:2 550:N 544:H 538:C 484:) 480:( 224:: 208:: 196:: 160:: 53:/

Index



AHFS
Drugs.com
Micromedex Detailed Consumer Information
License data
FDA
Amobarbital
Routes of
administration

IM
IV
ATC code
N05CA02
WHO
Legal status
Class B1
Schedule IV
Anlage III
Class B
Schedule II
Schedule III
Psychotropic Schedule III
Pharmacokinetic
Metabolism
Hepatic
Elimination half-life
Excretion
Renal
IUPAC name
CAS Number

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