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Allicin

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cannot deal with allicin’s mode of action and develop effective defence mechanism" and argue "that could be the key to sustainable drug design addressing serious problems with escalating emergence of multidrug-resistant bacterial strains".
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Alliinase is irreversibly deactivated below pH 3; as such, allicin is generally not produced in the body from the consumption of fresh or powdered garlic. Furthermore, allicin can be unstable, breaking down within 16 hours at 23 °C.
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Rabinkov A, Miron T, Konstantinovski L, Wilchek M, Mirelman D, Weiner L (February 1998). "The mode of action of allicin: trapping of radicals and interaction with thiol containing proteins".
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Marchese A, Barbieri R, Sanches-Silva A, Daglia M, Nabavi SF, Jafari NJ, Izadi M, Ajami M, Nabavi SM (2016). "Antifungal and antibacterial activities of allicin: A review".
617:. It is also known as allyl thiosulfinate. Its biological activity can be attributed to both its antioxidant activity and its reaction with thiol-containing proteins. 598:
into allicin, which is responsible for the aroma of fresh garlic. Allicin is unstable and quickly changes into a series of other sulfur-containing compounds such as
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Cavallito CJ, Bailey JH (1944). "Allicin, the Antibacterial Principle of Allium sativum. I. Isolation, Physical Properties and Antibacterial Action".
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functional group, R-S-(O)-S-R. The compound is not present in garlic unless tissue damage occurs, and is formed by the action of the enzyme
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Kourounakis PN, Rekka EA (November 1991). "Effect on active oxygen species of alliin and Allium sativum (garlic) powder".
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SOH), pyruvate, and ammonium ions. At room temperature, two molecules of allylsulfenic acid condense to form allicin.
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A study from 2021 has shown "a combination of the short half-life, high reactivity and non-specificity to particular
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Nikolic V, Stankovic M, Nikolic L, Cvetkovic D (January 2004). "Mechanism and kinetics of synthesis of allicin".
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Bettendorff L (2014). "Chapter 7 - Thiamine". In Zempleni J, Suttie JW, Gregory JF, Stover PJ (eds.).
301: 235: 4159: 4139: 3487: 3397: 3392: 3377: 3194: 2694: 2324: 2319: 2199: 870: 770: 372: 295: 4119: 3678: 3460: 1627: 777:, but as of 2016, the safety and efficacy of allicin to treat infections in people was unclear. 3981: 3828: 3545: 3417: 3323: 2689: 2334: 2076: 1869: 1594: 785: 3656: 2113: 1645: 1444:
Janská P, Knejzlík Z, Perumal AS, Jurok R, Tokárová V, Nicolau DV, et al. (2021-03-19).
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Allicin is an oily, slightly yellow liquid that gives garlic its distinctive odor. It is a
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Brodnitz MH, Pascale JV, Derslice LV (1971). "Flavor components of garlic extract".
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allicin (20 times the amount in a garlic clove) showed effectiveness to prevent the
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and John Hays Bailey in 1944. Allicin was discovered as part of efforts to create
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Borlinghaus J, Albrecht F, Gruhlke MC, Nwachukwu ID, Slusarenko AJ (August 2014).
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Borlinghaus J, Albrecht F, Gruhlke MC, Nwachukwu ID, Slusarenko AJ (August 2014).
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The biosynthesis of allicin commences with the conversion of cysteine into
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Ilic D, Nikolic V, Nikolic L, Stankovic M, Stanojevic L, Cakic M (2011).
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derivatives in the 1940s, mainly in Japan. Allicin became a model for
792:. A Cochrane review found this to be insufficient to draw conclusions. 485: 254: 236: 196: 3355: 3213: 2784: 4076: 4061: 4056: 4006: 4001: 3646: 3565: 3523: 3513: 2750: 2615: 1665: 769:
Allicin has been studied for its potential to treat various kinds of
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Except where otherwise noted, data are given for materials in their
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efforts to create other thiamine disulfides. The results included
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Research Communications in Chemical Pathology and Pharmacology
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Yu TH, Wu CM (1989). "Stability of Allicin in Garlic Juice".
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bacterial infections, as well as viral and fungal infections
741:-cysteine. Oxidation of this thioether gives the sulfoxide ( 156: 115: 914:
Block E (March 1985). "The Chemistry of Garlic and Onions".
360: 3777: 3611: 3356: 3302: 3263: 2954: 2917: 2785: 1612: 983: 275: 1443: 1550: 909: 907: 905: 1534:(Fifth ed.). Hoboken: CRC Press. pp. 267–324. 753:(PLP), cleaves alliin, generating allylsulfenic acid (CH 3662: 1243: 812:
It was first isolated and studied in the laboratory by
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Biochimica et Biophysica Acta (BBA) - General Subjects
902: 590:. When fresh garlic is chopped or crushed, the enzyme 2279: 1394: 400:
InChI=1S/C6H10OS2/c1-3-5-8-9(7)6-4-2/h3-4H,1-2,5-6H2
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InChI=1/C6H10OS2/c1-3-5-8-9(7)6-4-2/h3-4H,1-2,5-6H2
263: 1523: 1142:Garlic and Other Alliums: The Lore and the Science 1395:Lissiman E, Bhasale AL, Cohen M (November 2014). 73:2-Propene-1-sulfinothioic acid S-2-propenyl ester 4111: 1062: 956: 322: 4165:Transient receptor potential channel modulators 1502: 1092: 1067: 1065: 101: 1195:"Allicin: chemistry and biological properties" 1097: 1095: 1020:"Allicin: chemistry and biological properties" 521:< 25 °C (77 °F; 298 K) 2263: 1566: 64:-(Prop-2-en-1-yl) prop-2-ene-1-sulfinothioate 832:(thiamine tetrahydrofurfuryl disulfide) and 1529: 1401:The Cochrane Database of Systematic Reviews 649:form can also be generated by oxidation of 620: 2277: 2270: 2256: 1573: 1559: 1353: 1298:Hahn G (1996). Koch HP, Lawson LD (eds.). 1246:Journal of Agricultural and Food Chemistry 375: 226: 204: 1479: 1469: 1420: 1371: 1220: 1210: 1167:An introduction to organosulfur chemistry 1144:. Cambridge: Royal Society of Chemistry. 1045: 1035: 342: 1505:Journal of the American Chemical Society 1164: 371: 300: 4112: 2037: 1730: 1135: 1133: 217: 2450:CS gas (2-chlorobenzal malononitrile) 2251: 1554: 1329:Trends in Food Science and Technology 1188: 1186: 1139: 913: 403:Key: JDLKFOPOAOFWQN-UHFFFAOYSA-N 184: 164: 1297: 1270: 4022:N-(p-Amylcinnamoyl)anthranilic acid 3138:N-(p-Amylcinnamoyl)anthranilic acid 2878:N-(p-Amylcinnamoyl)anthranilic acid 1130: 977: 413:Key: JDLKFOPOAOFWQN-UHFFFAOYAO 313: 283: 13: 1496: 1285:10.1111/j.1365-2621.1989.tb07926.x 1183: 1011: 936:10.1038/scientificamerican0385-114 80:-Allyl prop-2-ene-1-sulfinothioate 14: 4176: 1354:Nahas R, Balla A (January 2011). 852:, the active piquant chemical in 2232: 2231: 2217:Garlic Is as Good as Ten Mothers 545: 466: 42: 33: 1437: 1388: 1347: 1320: 1291: 1264: 1237: 728: 641:but occurs naturally only as a 541:(at 25 °C , 100 kPa). 1413:10.1002/14651858.CD006206.pub4 1158: 950: 891:List of phytochemicals in food 475: 472: 460: 1: 4096:Receptor/signaling modulators 2445:CR gas (dibenzoxazepine; DBO) 1116:10.1016/s0304-4165(97)00104-9 896: 1471:10.1371/journal.pone.0248878 1397:"Garlic for the common cold" 7: 3724:Paracetamol (acetaminophen) 2632:Paracetamol (acetaminophen) 2502:Farnesyl thiosalicylic acid 2330:15-Deoxy-Δ-prostaglandin J2 843: 764: 10: 4181: 1580: 1341:10.1016/j.tifs.2016.03.010 1212:10.3390/molecules190812591 1037:10.3390/molecules190812591 807: 15: 4089: 3892: 3365: 3354: 3334: 3311: 3300: 3272: 3223: 3212: 3090: 2926: 2915: 2840: 2794: 2783: 2723: 2302: 2291: 2227: 2208: 2170: 2155:Beurre à la bourguignonne 2104: 2028: 1997: 1937: 1721: 1626: 1590: 1360:Canadian Family Physician 535: 447: 422: 387: 85: 70: 55: 50: 41: 32: 4125:Anti-inflammatory agents 2709:Umbellularia californica 2200:syn-Propanethial-S-oxide 771:multiple drug resistance 621:Structure and occurrence 16:Not to be confused with 3679:N-Arachidonoyl dopamine 3461:Andrographis paniculata 1273:Journal of Food Science 784:, a daily high dose of 4100:Ion channel modulators 3829:Tetrahydrocannabivarin 3324:Tripterygium wilfordii 2690:Tetrahydrocannabiorcol 1656:Common / Bulb 3657:Lysophosphatidic acid 2114:List of garlic dishes 1646:Cipolla di Giarratana 1304:L and related species 1005:10.2298/FUPCT1101009I 625:Allicin features the 584:organosulfur compound 4135:Dietary antioxidants 4037:Pregnenolone sulfate 3858:Euphorbia resinifera 3800:Euphorbia resinifera 3729:Phenylacetylrinvanil 3689:N-Oleoylethanolamide 3637:Homodihydrocapsaicin 3025:Pregnenolone sulfate 2888:Pregnenolone sulfate 2695:Thiopropanal S-oxide 2680:Tetrahydrocannabinol 2368:Allyl isothiocyanate 1947:List of onion dishes 1636:Bangalore rose onion 1532:Handbook of vitamins 850:Allyl isothiocyanate 814:Chester J. Cavallito 57:Preferred IUPAC name 3942:Cannabigerolic acid 3704:Nordihydrocapsaicin 3665:(acidic conditions) 1517:10.1021/ja01239a048 1462:2021PLoSO..1648878J 1258:10.1021/jf60174a007 1165:Cremlyn RJ (1996). 993:Facta Universitatis 928:1985SciAm.252c.114B 916:Scientific American 822:medicinal chemistry 751:pyridoxal phosphate 493: g·mol 146:Beilstein Reference 29: 3905:Vernonia tweediana 3484:African blue basil 3456:Bisandrographolide 3042:Steviol glycosides 2995:Hydroxycitronellal 2741:Dehydroligustilide 2561:Angelica acutiloba 2475:Dehydroligustilide 2220:(1980 documentary) 2190:Diallyl trisulfide 884:chemical found in 568:Infobox references 501:Colourless liquid 27: 4107: 4106: 4085: 4084: 4017:Meclofenamic acid 3823:melegueta peppers 3694:Nonivamide (PAVA) 3430:melegueta peppers 3350: 3349: 3296: 3295: 3208: 3207: 3128:Meclofenamic acid 3051:Stevia rebaudiana 2911: 2910: 2873:Meclofenamic acid 2779: 2778: 2669:melegueta peppers 2642:Phenacyl chloride 2597:N-Methylmaleimide 2587:Methyl salicylate 2532:Hydrogen peroxide 2485:Diallyl disulfide 2347:melegueta peppers 2245: 2244: 2185:Diallyl disulfide 2100: 2099: 1933: 1932: 1541:978-1-4665-1557-4 1313:978-0-683-18147-0 799:are reasons most 749:, which contains 740: 651:diallyl disulfide 600:diallyl disulfide 576:Chemical compound 574: 573: 356:CompTox Dashboard 134:Interactive image 127:Interactive image 4172: 3952:Cannabigerovarin 3684:N-Oleoyldopamine 3590:Euodia ruticarpa 3556:Dihydrocapsaicin 3363: 3362: 3359: 3309: 3308: 3305: 3221: 3220: 3217: 2965:Cooling Agent 10 2924: 2923: 2920: 2792: 2791: 2788: 2310:4-Hydroxynonenal 2300: 2299: 2296: 2281: 2272: 2265: 2258: 2249: 2248: 2235: 2234: 2171:Garlic and onion 2077:…sphaerocephalon 2035: 2034: 1998:Garlic cultivars 1870:…sphaerocephalon 1728: 1727: 1575: 1568: 1561: 1552: 1551: 1546: 1545: 1527: 1521: 1520: 1500: 1494: 1493: 1483: 1473: 1441: 1435: 1434: 1424: 1407:(11): CD006206. 1392: 1386: 1385: 1375: 1351: 1345: 1344: 1324: 1318: 1317: 1295: 1289: 1288: 1268: 1262: 1261: 1241: 1235: 1234: 1224: 1214: 1205:(8): 12591–618. 1190: 1181: 1180: 1162: 1156: 1155: 1140:Block E (2010). 1137: 1128: 1127: 1099: 1090: 1089: 1069: 1060: 1059: 1049: 1039: 1030:(8): 12591–618. 1015: 1009: 1008: 990: 981: 975: 974: 954: 948: 947: 911: 738: 602:. Allicin is an 558: 552: 549: 548: 492: 477: 474: 468: 462: 455:Chemical formula 434:O=S(SC\C=C)C\C=C 380: 379: 364: 362: 346: 326: 315: 304: 287: 267: 238: 230: 219: 208: 188: 168: 136: 129: 105: 46: 37: 30: 26: 4180: 4179: 4175: 4174: 4173: 4171: 4170: 4169: 4160:Allyl compounds 4140:Pungent flavors 4110: 4109: 4108: 4103: 4081: 4072:Tolfenamic acid 3992:Flufenamic acid 3888: 3795:Resiniferatoxin 3788:Ruta graveolens 3551:Diacyl glycerol 3346: 3330: 3292: 3288: 3268: 3254: 3204: 3190:Tolfenamic acid 3183:Ruta graveolens 3123:Flufenamic acid 3086: 3035:Ruta graveolens 2946:(intracellular) 2907: 2903:Tolfenamic acid 2858:Flufenamic acid 2836: 2812:Diacyl glycerol 2775: 2719: 2405:Cannabichromene 2315:4-Oxo-2-nonenal 2287: 2276: 2246: 2241: 2223: 2204: 2195:Allyl mercaptan 2172: 2166: 2157:(garlic butter) 2096: 2024: 1993: 1929: 1717: 1628:Onion cultivars 1622: 1586: 1579: 1549: 1542: 1528: 1524: 1501: 1497: 1456:(3): e0248878. 1442: 1438: 1393: 1389: 1352: 1348: 1325: 1321: 1314: 1296: 1292: 1269: 1265: 1242: 1238: 1191: 1184: 1177: 1163: 1159: 1152: 1138: 1131: 1100: 1093: 1070: 1063: 1016: 1012: 988: 982: 978: 955: 951: 912: 903: 899: 846: 810: 767: 760: 756: 731: 719: 715: 711: 707: 703: 699: 695: 688: 684: 680: 676: 672: 668: 664: 660: 623: 577: 570: 565: 564: 563:  ?) 554: 550: 546: 542: 490: 480: 471: 465: 457: 443: 440: 435: 430: 429: 418: 415: 414: 411: 405: 404: 401: 395: 394: 383: 365: 358: 349: 329: 316: 290: 270: 257: 248: 211: 191: 171: 148: 139: 119: 108: 95: 81: 76: 74: 66: 65: 25: 12: 11: 5: 4178: 4168: 4167: 4162: 4157: 4152: 4147: 4142: 4137: 4132: 4127: 4122: 4120:Thiosulfinates 4105: 4104: 4090: 4087: 4086: 4083: 4082: 4080: 4079: 4074: 4069: 4064: 4059: 4054: 4049: 4044: 4039: 4034: 4029: 4024: 4019: 4014: 4009: 4004: 3999: 3994: 3989: 3984: 3979: 3974: 3969: 3959: 3949: 3939: 3929: 3924: 3919: 3914: 3909: 3896: 3894: 3890: 3889: 3887: 3886: 3881: 3871: 3866: 3850: 3836: 3826: 3808: 3792: 3780: 3775: 3770: 3765: 3762:Dorrigo pepper 3755: 3741: 3734:Phorbol esters 3731: 3726: 3721: 3711: 3701: 3691: 3686: 3681: 3676: 3666: 3659: 3654: 3644: 3634: 3624: 3619: 3614: 3609: 3604: 3594: 3582: 3568: 3563: 3553: 3548: 3543: 3521: 3511: 3504:Cannabidivarin 3501: 3491: 3472:camphor laurel 3465: 3453: 3448: 3443: 3433: 3415: 3410: 3405: 3400: 3395: 3390: 3385: 3380: 3375: 3369: 3367: 3360: 3352: 3351: 3348: 3347: 3345: 3344: 3338: 3336: 3332: 3331: 3329: 3328: 3315: 3313: 3306: 3298: 3297: 3294: 3293: 3291: 3290: 3286: 3282: 3276: 3274: 3270: 3269: 3267: 3266: 3261: 3256: 3252: 3248: 3243: 3238: 3233: 3227: 3225: 3218: 3210: 3209: 3206: 3205: 3203: 3202: 3197: 3192: 3187: 3175: 3170: 3165: 3160: 3155: 3150: 3140: 3135: 3133:Mefenamic acid 3130: 3125: 3120: 3115: 3110: 3105: 3100: 3094: 3092: 3088: 3087: 3085: 3084: 3079: 3074: 3055: 3039: 3027: 3022: 3017: 3007: 3002: 2997: 2992: 2987: 2982: 2977: 2967: 2962: 2957: 2952: 2947: 2941: 2936: 2930: 2928: 2921: 2913: 2912: 2909: 2908: 2906: 2905: 2900: 2895: 2890: 2885: 2880: 2875: 2870: 2865: 2860: 2855: 2850: 2844: 2842: 2838: 2837: 2835: 2834: 2829: 2826:St John's wort 2819: 2814: 2809: 2806:St John's wort 2798: 2796: 2789: 2781: 2780: 2777: 2776: 2774: 2773: 2768: 2763: 2753: 2748: 2738: 2733: 2727: 2725: 2721: 2720: 2718: 2717: 2712: 2702: 2692: 2687: 2677: 2672: 2654: 2651:Dorrigo pepper 2644: 2639: 2634: 2629: 2619: 2609: 2599: 2594: 2584: 2579: 2572:Sichuan pepper 2565: 2549: 2544: 2542:Isothiocyanate 2539: 2534: 2529: 2524: 2519: 2509: 2504: 2499: 2487: 2482: 2472: 2462: 2452: 2447: 2442: 2435:Cinnamaldehyde 2432: 2422: 2412: 2402: 2397: 2392: 2387: 2365: 2355: 2350: 2332: 2327: 2322: 2317: 2312: 2306: 2304: 2297: 2289: 2288: 2275: 2274: 2267: 2260: 2252: 2243: 2242: 2240: 2239: 2228: 2225: 2224: 2222: 2221: 2212: 2210: 2206: 2205: 2203: 2202: 2197: 2192: 2187: 2182: 2176: 2174: 2168: 2167: 2165: 2164: 2159: 2151: 2149:Garlic chutney 2146: 2141: 2136: 2131: 2126: 2121: 2116: 2110: 2108: 2102: 2101: 2098: 2097: 2095: 2094: 2089: 2084: 2079: 2074: 2069: 2064: 2059: 2054: 2049: 2043: 2041: 2032: 2030:Garlic species 2026: 2025: 2023: 2022: 2017: 2012: 2007: 2001: 1999: 1995: 1994: 1992: 1991: 1986: 1981: 1976: 1975: 1974: 1969: 1959: 1954: 1949: 1943: 1941: 1935: 1934: 1931: 1930: 1928: 1927: 1922: 1917: 1912: 1907: 1902: 1897: 1892: 1890:…tribracteatum 1887: 1882: 1877: 1872: 1867: 1862: 1857: 1852: 1847: 1842: 1837: 1832: 1827: 1822: 1817: 1812: 1807: 1802: 1797: 1792: 1787: 1782: 1777: 1772: 1767: 1762: 1757: 1752: 1747: 1742: 1736: 1734: 1725: 1719: 1718: 1716: 1715: 1710: 1705: 1700: 1695: 1690: 1685: 1680: 1678:Figueres onion 1675: 1674: 1673: 1668: 1663: 1653: 1648: 1643: 1638: 1632: 1630: 1624: 1623: 1621: 1620: 1615: 1610: 1605: 1600: 1591: 1588: 1587: 1578: 1577: 1570: 1563: 1555: 1548: 1547: 1540: 1522: 1495: 1436: 1387: 1346: 1319: 1312: 1302:Allium sativum 1290: 1263: 1236: 1182: 1175: 1157: 1151:978-0854041909 1150: 1129: 1091: 1061: 1010: 976: 949: 900: 898: 895: 894: 893: 888: 874:-Propanethial- 868: 845: 842: 809: 806: 782:clinical trial 766: 763: 758: 754: 745:). The enzyme 730: 727: 722: 721: 717: 713: 709: 705: 701: 697: 693: 690: 686: 682: 678: 674: 670: 666: 662: 658: 622: 619: 586:obtained from 575: 572: 571: 566: 544: 543: 539:standard state 536: 533: 532: 529: 523: 522: 519: 513: 512: 509: 503: 502: 499: 495: 494: 488: 482: 481: 478: 469: 463: 458: 453: 450: 449: 445: 444: 442: 441: 439:C=CCSS(=O)CC=C 438: 436: 433: 425: 424: 423: 420: 419: 417: 416: 412: 409: 408: 406: 402: 399: 398: 390: 389: 388: 385: 384: 382: 381: 368: 366: 354: 351: 350: 348: 347: 339: 337: 331: 330: 328: 327: 319: 317: 309: 306: 305: 298: 292: 291: 289: 288: 280: 278: 272: 271: 269: 268: 260: 258: 253: 250: 249: 247: 246: 242: 240: 232: 231: 221: 213: 212: 210: 209: 201: 199: 193: 192: 190: 189: 181: 179: 173: 172: 170: 169: 161: 159: 153: 152: 149: 144: 141: 140: 138: 137: 130: 122: 120: 113: 110: 109: 107: 106: 98: 96: 91: 88: 87: 83: 82: 72: 68: 67: 60: 59: 53: 52: 48: 47: 39: 38: 9: 6: 4: 3: 2: 4177: 4166: 4163: 4161: 4158: 4156: 4153: 4151: 4148: 4146: 4143: 4141: 4138: 4136: 4133: 4131: 4128: 4126: 4123: 4121: 4118: 4117: 4115: 4102: 4101: 4097: 4094: 4088: 4078: 4075: 4073: 4070: 4068: 4065: 4063: 4060: 4058: 4055: 4053: 4052:Ruthenium red 4050: 4048: 4045: 4043: 4040: 4038: 4035: 4033: 4032:Niflumic acid 4030: 4028: 4025: 4023: 4020: 4018: 4015: 4013: 4010: 4008: 4005: 4003: 4000: 3998: 3995: 3993: 3990: 3988: 3985: 3983: 3980: 3978: 3975: 3973: 3970: 3967: 3963: 3960: 3957: 3953: 3950: 3947: 3943: 3940: 3937: 3933: 3930: 3928: 3925: 3923: 3920: 3918: 3915: 3913: 3910: 3907: 3906: 3901: 3900:α-Spinasterol 3898: 3897: 3895: 3891: 3885: 3882: 3879: 3875: 3872: 3870: 3867: 3864: 3863: 3859: 3854: 3851: 3848: 3844: 3840: 3837: 3834: 3830: 3827: 3824: 3820: 3816: 3812: 3809: 3806: 3805: 3801: 3796: 3793: 3790: 3789: 3784: 3781: 3779: 3776: 3774: 3771: 3769: 3766: 3763: 3759: 3756: 3753: 3749: 3745: 3742: 3739: 3735: 3732: 3730: 3727: 3725: 3722: 3719: 3715: 3712: 3709: 3705: 3702: 3699: 3695: 3692: 3690: 3687: 3685: 3682: 3680: 3677: 3674: 3670: 3667: 3664: 3660: 3658: 3655: 3652: 3648: 3645: 3642: 3638: 3635: 3632: 3628: 3627:Homocapsaicin 3625: 3623: 3620: 3618: 3615: 3613: 3610: 3608: 3605: 3602: 3598: 3595: 3592: 3591: 3586: 3583: 3580: 3576: 3572: 3569: 3567: 3564: 3561: 3557: 3554: 3552: 3549: 3547: 3544: 3541: 3540:wild bergamot 3537: 3533: 3529: 3525: 3522: 3519: 3515: 3512: 3509: 3505: 3502: 3499: 3495: 3492: 3489: 3488:camphor basil 3485: 3481: 3477: 3473: 3469: 3466: 3463: 3462: 3457: 3454: 3452: 3449: 3447: 3444: 3441: 3437: 3434: 3431: 3427: 3423: 3419: 3416: 3414: 3411: 3409: 3406: 3404: 3401: 3399: 3396: 3394: 3391: 3389: 3386: 3384: 3381: 3379: 3376: 3374: 3371: 3370: 3368: 3364: 3361: 3358: 3353: 3343: 3342:Ruthenium red 3340: 3339: 3337: 3333: 3326: 3325: 3320: 3317: 3316: 3314: 3310: 3307: 3304: 3299: 3289: 3283: 3281: 3278: 3277: 3275: 3271: 3265: 3262: 3260: 3257: 3255: 3249: 3247: 3244: 3242: 3239: 3237: 3234: 3232: 3229: 3228: 3226: 3222: 3219: 3216: 3211: 3201: 3198: 3196: 3193: 3191: 3188: 3185: 3184: 3179: 3176: 3174: 3173:Ruthenium red 3171: 3169: 3166: 3164: 3161: 3159: 3156: 3154: 3153:Niflumic acid 3151: 3148: 3144: 3141: 3139: 3136: 3134: 3131: 3129: 3126: 3124: 3121: 3119: 3116: 3114: 3111: 3109: 3106: 3104: 3101: 3099: 3096: 3095: 3093: 3089: 3083: 3080: 3078: 3075: 3073:; indirectly) 3072: 3068: 3064: 3060: 3056: 3053: 3052: 3047: 3043: 3040: 3037: 3036: 3031: 3028: 3026: 3023: 3021: 3018: 3015: 3011: 3008: 3006: 3003: 3001: 2998: 2996: 2993: 2991: 2988: 2986: 2983: 2981: 2980:Frescolat MGA 2978: 2975: 2971: 2968: 2966: 2963: 2961: 2958: 2956: 2953: 2951: 2948: 2945: 2942: 2940: 2937: 2935: 2932: 2931: 2929: 2925: 2922: 2919: 2914: 2904: 2901: 2899: 2896: 2894: 2891: 2889: 2886: 2884: 2883:Niflumic acid 2881: 2879: 2876: 2874: 2871: 2869: 2866: 2864: 2861: 2859: 2856: 2854: 2851: 2849: 2846: 2845: 2843: 2839: 2833: 2830: 2827: 2823: 2820: 2818: 2815: 2813: 2810: 2807: 2803: 2800: 2799: 2797: 2793: 2790: 2787: 2782: 2772: 2771:Ruthenium red 2769: 2767: 2764: 2761: 2757: 2754: 2752: 2749: 2746: 2742: 2739: 2737: 2734: 2732: 2729: 2728: 2726: 2722: 2716: 2713: 2710: 2706: 2703: 2700: 2696: 2693: 2691: 2688: 2685: 2681: 2678: 2676: 2673: 2670: 2666: 2662: 2658: 2655: 2652: 2648: 2645: 2643: 2640: 2638: 2635: 2633: 2630: 2627: 2623: 2620: 2617: 2613: 2610: 2607: 2603: 2600: 2598: 2595: 2592: 2588: 2585: 2583: 2582:Methylglyoxal 2580: 2577: 2573: 2569: 2566: 2563: 2562: 2557: 2553: 2550: 2548: 2545: 2543: 2540: 2538: 2535: 2533: 2530: 2528: 2525: 2523: 2520: 2517: 2513: 2510: 2508: 2505: 2503: 2500: 2497: 2496: 2491: 2488: 2486: 2483: 2480: 2476: 2473: 2470: 2466: 2463: 2460: 2456: 2455:Cuminaldehyde 2453: 2451: 2448: 2446: 2443: 2440: 2436: 2433: 2430: 2426: 2423: 2420: 2416: 2413: 2410: 2406: 2403: 2401: 2398: 2396: 2393: 2391: 2388: 2385: 2381: 2377: 2373: 2369: 2366: 2363: 2359: 2356: 2354: 2351: 2348: 2344: 2340: 2336: 2333: 2331: 2328: 2326: 2323: 2321: 2318: 2316: 2313: 2311: 2308: 2307: 2305: 2301: 2298: 2295: 2290: 2286: 2283: 2273: 2268: 2266: 2261: 2259: 2254: 2253: 2250: 2238: 2230: 2229: 2226: 2219: 2218: 2214: 2213: 2211: 2207: 2201: 2198: 2196: 2193: 2191: 2188: 2186: 2183: 2181: 2178: 2177: 2175: 2169: 2163: 2160: 2158: 2156: 2152: 2150: 2147: 2145: 2142: 2140: 2137: 2135: 2132: 2130: 2127: 2125: 2122: 2120: 2117: 2115: 2112: 2111: 2109: 2107: 2103: 2093: 2090: 2088: 2085: 2083: 2080: 2078: 2075: 2073: 2070: 2068: 2065: 2063: 2062:…neapolitanum 2060: 2058: 2055: 2053: 2050: 2048: 2045: 2044: 2042: 2040: 2036: 2033: 2031: 2027: 2021: 2018: 2016: 2015:Snow Mountain 2013: 2011: 2010:Garlic chives 2008: 2006: 2003: 2002: 2000: 1996: 1990: 1987: 1985: 1982: 1980: 1977: 1973: 1972:Zwiebelkuchen 1970: 1968: 1965: 1964: 1963: 1960: 1958: 1955: 1953: 1950: 1948: 1945: 1944: 1942: 1940: 1936: 1926: 1923: 1921: 1918: 1916: 1913: 1911: 1908: 1906: 1903: 1901: 1898: 1896: 1893: 1891: 1888: 1886: 1883: 1881: 1878: 1876: 1873: 1871: 1868: 1866: 1865:…siskiyouense 1863: 1861: 1858: 1856: 1853: 1851: 1848: 1846: 1843: 1841: 1838: 1836: 1833: 1831: 1828: 1826: 1823: 1821: 1818: 1816: 1813: 1811: 1808: 1806: 1803: 1801: 1798: 1796: 1795:…campanulatum 1793: 1791: 1788: 1786: 1783: 1781: 1778: 1776: 1773: 1771: 1768: 1766: 1763: 1761: 1758: 1756: 1755:…ampeloprasum 1753: 1751: 1748: 1746: 1743: 1741: 1738: 1737: 1735: 1733: 1729: 1726: 1724: 1723:Onion species 1720: 1714: 1711: 1709: 1706: 1704: 1701: 1699: 1696: 1694: 1691: 1689: 1686: 1684: 1681: 1679: 1676: 1672: 1669: 1667: 1664: 1662: 1659: 1658: 1657: 1654: 1652: 1649: 1647: 1644: 1642: 1639: 1637: 1634: 1633: 1631: 1629: 1625: 1619: 1616: 1614: 1611: 1609: 1606: 1604: 1601: 1599: 1597: 1593: 1592: 1589: 1585: 1584: 1576: 1571: 1569: 1564: 1562: 1557: 1556: 1553: 1543: 1537: 1533: 1526: 1518: 1514: 1510: 1506: 1499: 1491: 1487: 1482: 1477: 1472: 1467: 1463: 1459: 1455: 1451: 1447: 1440: 1432: 1428: 1423: 1418: 1414: 1410: 1406: 1402: 1398: 1391: 1383: 1379: 1374: 1369: 1365: 1361: 1357: 1350: 1342: 1338: 1334: 1330: 1323: 1315: 1309: 1305: 1301: 1294: 1286: 1282: 1278: 1274: 1267: 1259: 1255: 1251: 1247: 1240: 1232: 1228: 1223: 1218: 1213: 1208: 1204: 1200: 1196: 1189: 1187: 1178: 1176:0-471-95512-4 1172: 1168: 1161: 1153: 1147: 1143: 1136: 1134: 1125: 1121: 1117: 1113: 1110:(2): 233–44. 1109: 1105: 1098: 1096: 1087: 1083: 1079: 1075: 1074:Die Pharmazie 1068: 1066: 1057: 1053: 1048: 1043: 1038: 1033: 1029: 1025: 1021: 1014: 1006: 1002: 998: 994: 987: 980: 972: 968: 965:(2): 249–52. 964: 960: 953: 945: 941: 937: 933: 929: 925: 921: 917: 910: 908: 906: 901: 892: 889: 887: 883: 879: 877: 873: 869: 867: 863: 859: 855: 851: 848: 847: 841: 839: 835: 834:benfothiamine 831: 830:fursultiamine 827: 823: 819: 815: 805: 802: 798: 793: 791: 787: 783: 778: 776: 772: 762: 752: 748: 744: 736: 726: 691: 656: 655: 654: 652: 648: 644: 640: 637:. Allicin is 636: 632: 628: 627:thiosulfinate 618: 616: 615:sulfenic acid 612: 607: 605: 601: 597: 593: 589: 585: 581: 569: 562: 557: 540: 534: 530: 528: 527:Boiling point 525: 524: 520: 518: 517:Melting point 515: 514: 510: 508: 505: 504: 500: 497: 496: 489: 487: 484: 483: 459: 456: 452: 451: 446: 437: 432: 431: 428: 421: 407: 397: 396: 393: 386: 378: 374: 373:DTXSID6043707 370: 369: 367: 357: 353: 352: 345: 341: 340: 338: 336: 333: 332: 325: 321: 320: 318: 312: 308: 307: 303: 299: 297: 294: 293: 286: 282: 281: 279: 277: 274: 273: 266: 262: 261: 259: 256: 252: 251: 244: 243: 241: 239: 234: 233: 229: 225: 222: 220: 218:ECHA InfoCard 215: 214: 207: 203: 202: 200: 198: 195: 194: 187: 183: 182: 180: 178: 175: 174: 167: 163: 162: 160: 158: 155: 154: 150: 147: 143: 142: 135: 131: 128: 124: 123: 121: 117: 112: 111: 104: 100: 99: 97: 94: 90: 89: 84: 79: 69: 63: 58: 54: 49: 45: 40: 36: 31: 23: 19: 4092: 4091: 3932:Cannabigerol 3903: 3856: 3798: 3786: 3748:black pepper 3708:chili pepper 3641:chili pepper 3631:chili pepper 3622:Hepoxilin B3 3617:Hepoxilin A3 3588: 3560:chili pepper 3518:chili pepper 3459: 3435: 3322: 3181: 3108:Clotrimazole 3049: 3033: 2985:Frescolat ML 2893:Progesterone 2802:Adhyperforin 2715:WIN 55,212-2 2708: 2559: 2527:Hepoxilin B3 2522:Hepoxilin A3 2493: 2425:Cannabigerol 2357: 2215: 2179: 2173:constituents 2154: 2144:Garlic bread 2139:Garlic press 2119:Black garlic 2038: 1925:…yosemitense 1920:…victorialis 1905:…tuolumnense 1810:…cratericola 1750:…aflatunense 1731: 1595: 1581: 1531: 1525: 1511:(11): 1950. 1508: 1504: 1498: 1453: 1449: 1439: 1404: 1400: 1390: 1363: 1359: 1349: 1332: 1328: 1322: 1303: 1299: 1293: 1276: 1272: 1266: 1252:(2): 273–5. 1249: 1245: 1239: 1202: 1198: 1166: 1160: 1141: 1107: 1103: 1077: 1073: 1027: 1023: 1013: 996: 992: 979: 962: 958: 952: 922:(3): 114–9. 919: 915: 882:lachrymatory 875: 871: 826:sulbutiamine 811: 794: 779: 768: 734: 732: 729:Biosynthesis 723: 624: 608: 579: 578: 186:ChEMBL359965 86:Identifiers 77: 75:3-prop-1-ene 71:Other names 61: 4155:Antifungals 4130:Antibiotics 4067:Tivanisiran 3972:Capsazepine 3884:Zucapsaicin 3752:long pepper 3718:Pacific yew 3607:GSK1016790A 3494:Cannabidiol 3480:camphorweed 3168:RQ-00203078 3163:PF-05105679 3103:Capsazepine 2868:GSK2293017A 2832:Substance P 2817:GSK1702934A 2766:PF-04745637 2705:Umbellulone 2626:Pacific yew 2612:Oleocanthal 2591:wintergreen 2552:Ligustilide 2415:Cannabidiol 2380:horseradish 2162:Garlic soup 2106:Garlic food 2082:…triquetrum 2052:…drummondii 1989:Sogan-dolma 1967:Flammkuchen 1900:…triquetrum 1880:…stipitatum 1840:…platycaule 1825:…fistulosum 1820:…cristophii 1775:…bisceptrum 1770:…atrorubens 1760:…amplectens 1745:…acuminatum 1366:(1): 31–6. 1080:(1): 10–4. 999:(1): 9–20. 862:horseradish 838:glutathione 790:common cold 780:In a small 685:SOH + 2 RCO 604:antifeedant 531:decomposes 511:1.112 g cm 498:Appearance 448:Properties 224:100.007.935 166:CHEBI:28411 4114:Categories 3962:Cannabinol 3862:pooissonii 3853:Tinyatoxin 3804:pooissonii 3768:Probenecid 3758:Polygodial 3714:Paclitaxel 3698:PAVA spray 3585:Evodiamine 3536:pepperwort 3451:Anandamide 3418:α-Sanshool 3366:Activators 3319:Triptolide 3312:Activators 3224:Activators 3200:TRPM4-IN-5 3118:Elismetrep 3046:stevioside 2974:eucalyptus 2970:Eucalyptol 2934:ADP-ribose 2927:Activators 2863:GSK417651A 2822:Hyperforin 2795:Activators 2675:Tear gases 2647:Polygodial 2637:PF-4840154 2622:Paclitaxel 2490:Dicentrine 2400:Bradykinin 2335:α-Sanshool 2303:Activators 2285:modulators 2134:Garlic oil 2124:Persillade 2047:…canadense 1979:Onion ring 1962:Onion cake 1939:Onion food 1910:…unifolium 1895:…tricoccum 1875:…stellatum 1860:…shevockii 1855:…sanbornii 1835:…monanthum 1790:…caeruleum 1780:…bolanderi 1279:(4): 977. 897:References 700:SOH → CH 486:Molar mass 344:3C39BY17Y6 255:IUPHAR/BPS 197:ChemSpider 114:3D model ( 93:CAS Number 4093:See also: 4077:TRPV3-74a 4062:SB-705498 4057:SB-366791 4007:Lanthanum 4002:HC-067047 3922:Asivatrep 3783:Rutamarin 3647:Incensole 3597:Gingerols 3566:Estradiol 3542:, others) 3524:Carvacrol 3514:Capsaicin 3408:13-oxoODE 3398:12S-HpETE 3378:5',6'-EET 3178:Rutamarin 3077:Thio-BCTC 3030:Rutamarin 2960:Coolact P 2751:HC-030031 2616:olive oil 2512:Gingerols 2325:12S-HpETE 1830:…koreanum 1805:…chinense 1785:…burlewii 1740:…abramsii 1335:: 49–56. 1199:Molecules 1169:. Wiley. 1024:Molecules 786:extracted 747:alliinase 631:alliinase 611:thioester 594:converts 592:alliinase 245:208-727-7 237:EC Number 4027:NGD-8243 4012:Mavatrep 3997:GRC-6211 3966:cannabis 3956:cannabis 3946:cannabis 3936:cannabis 3917:AMG-9810 3893:Blockers 3874:Vanillin 3869:Tramadol 3833:cannabis 3811:Shogaols 3744:Piperine 3508:cannabis 3498:cannabis 3476:rosemary 3393:12S-HETE 3388:9-oxoODE 3335:Blockers 3285:PI(4,5)P 3273:Blockers 3251:PI(3,5)P 3158:Ononetin 3143:Nicotine 3091:Blockers 3067:fructose 3059:tastants 3005:Linalool 2990:Geraniol 2950:CIM-0216 2841:Blockers 2756:Nicotine 2731:A-967079 2724:Blockers 2684:cannabis 2657:Shogaols 2602:Nicotine 2568:Linalool 2507:Formalin 2469:turmeric 2465:Curcumin 2439:cinnamon 2429:cannabis 2419:cannabis 2409:cannabis 2395:ASP-7663 2353:Acrolein 2237:Category 2092:…vineale 2087:…ursinum 2005:Elephant 1952:Blooming 1915:…validum 1885:…textile 1850:…punctum 1845:…praecox 1815:…crispum 1800:…cernuum 1693:Scallion 1651:Cocktail 1490:33740023 1450:PLOS ONE 1431:25386977 1382:21322286 1231:25153873 1086:14964414 1056:25153873 858:radishes 844:See also 818:thiamine 801:bacteria 797:proteins 775:in vitro 765:Research 677:O → 2 CH 643:racemate 151:1752823 103:539-86-6 28:Allicin 18:Allysine 4047:RN-9893 4042:RN-1734 3912:AMG-517 3878:vanilla 3847:oregano 3819:Sichuan 3797:(RTX) ( 3773:Protons 3736:(e.g., 3669:Menthol 3651:incense 3571:Eugenol 3528:oregano 3468:Camphor 3436:Allicin 3426:Sichuan 3413:20-HETE 3403:13-HODE 3246:ML2-SA1 3147:tobacco 3098:AMG-333 3071:sucrose 3063:glucose 3061:(e.g., 3044:(e.g., 3010:Menthol 2944:Calcium 2760:tobacco 2736:AM-0902 2665:Sichuan 2606:tobacco 2495:Lindera 2372:mustard 2358:Allicin 2343:Sichuan 2320:4,5-EET 2282:channel 2209:Related 2180:Allicin 2072:…roseum 2067:…nigrum 2039:Allium… 1984:Pickled 1765:…anceps 1732:Allium… 1713:Vidalia 1698:Shallot 1598:species 1481:7978267 1458:Bibcode 1422:6465033 1373:3024156 1222:6271412 1124:9528659 1047:6271412 971:1667340 944:3975593 924:Bibcode 854:mustard 808:History 737:-allyl- 708:S(O)SCH 673:H + H 669:+ 2 RCO 647:racemic 580:Allicin 561:what is 559: ( 507:Density 311:PubChem 302:Allicin 22:halicin 4150:Garlic 4145:Allium 3987:DHEA-S 3839:Thymol 3815:ginger 3738:4α-PDD 3601:ginger 3440:garlic 3422:ginger 3383:9-HODE 3280:ML-SI3 3241:ML-SA1 3236:MK6-83 3057:Sweet 3020:PMD 38 3000:Icilin 2853:DHEA-S 2745:celery 2661:ginger 2556:celery 2547:JT-010 2537:Icilin 2516:ginger 2479:celery 2384:wasabi 2376:radish 2362:garlic 2339:ginger 2129:Pistou 1688:Potato 1661:Yellow 1641:Calçot 1608:Garlic 1603:Chives 1596:Allium 1583:Allium 1538:  1488:  1478:  1429:  1419:  1380:  1370:  1310:  1229:  1219:  1173:  1148:  1122:  1084:  1054:  1044:  969:  942:  886:onions 880:, the 878:-oxide 866:wasabi 743:alliin 645:. The 639:chiral 635:alliin 596:alliin 588:garlic 582:is an 556:verify 553:  491:162.26 427:SMILES 285:C07600 177:ChEMBL 51:Names 3977:DCDPC 3843:thyme 3579:clove 3575:basil 3532:thyme 3446:AM404 3373:2-APB 3259:SF-22 3231:EVP21 3215:TRPML 3113:DCDPC 3082:WS-12 2848:DCDPC 2699:onion 2576:thyme 2498:spp.) 2459:cumin 2390:AM404 2057:…moly 1957:Fried 1703:Sweet 1683:Pearl 1671:White 1618:Onion 989:(PDF) 757:=CHCH 712:CH=CH 704:=CHCH 696:=CHCH 681:=CHCH 661:CH=CH 392:InChI 324:65036 206:58548 157:ChEBI 116:JSmol 3982:DHEA 3927:BCTC 3821:and 3778:RhTx 3673:mint 3661:Low 3612:Heat 3546:DHEA 3428:and 3357:TRPV 3303:TRPP 3264:SN-2 3195:TPPO 3014:mint 2955:Cold 2939:BCTC 2918:TRPM 2898:Pyr3 2786:TRPC 2667:and 2345:and 2294:TRPA 2020:Solo 1708:Tree 1613:Leek 1536:ISBN 1486:PMID 1427:PMID 1405:2020 1378:PMID 1308:ISBN 1227:PMID 1171:ISBN 1146:ISBN 1120:PMID 1108:1379 1082:PMID 1052:PMID 967:PMID 940:PMID 864:and 692:2 CH 657:(SCH 335:UNII 296:MeSH 276:KEGG 265:2419 3048:) ( 2280:TRP 1666:Red 1513:doi 1476:PMC 1466:doi 1417:PMC 1409:doi 1368:PMC 1337:doi 1281:doi 1254:doi 1217:PMC 1207:doi 1112:doi 1042:PMC 1032:doi 1001:doi 932:doi 920:252 872:syn 716:+ H 633:on 613:of 361:EPA 314:CID 20:or 4116:: 4098:• 3845:, 3817:, 3750:, 3663:pH 3577:, 3538:, 3534:, 3530:, 3486:, 3482:, 3478:, 3474:, 3424:, 3069:, 3065:, 2663:, 2574:, 2558:, 2382:, 2378:, 2374:, 2341:, 1509:66 1507:. 1484:. 1474:. 1464:. 1454:16 1452:. 1448:. 1425:. 1415:. 1403:. 1399:. 1376:. 1364:57 1362:. 1358:. 1333:52 1331:. 1277:54 1275:. 1250:19 1248:. 1225:. 1215:. 1203:19 1201:. 1197:. 1185:^ 1132:^ 1118:. 1106:. 1094:^ 1078:59 1076:. 1064:^ 1050:. 1040:. 1028:19 1026:. 1022:. 995:. 991:. 963:74 961:. 938:. 930:. 918:. 904:^ 860:, 856:, 840:. 828:, 653:: 470:10 3968:) 3964:( 3958:) 3954:( 3948:) 3944:( 3938:) 3934:( 3908:) 3902:( 3880:) 3876:( 3865:) 3860:/ 3855:( 3849:) 3841:( 3835:) 3831:( 3825:) 3813:( 3807:) 3802:/ 3791:) 3785:( 3764:) 3760:( 3754:) 3746:( 3740:) 3720:) 3716:( 3710:) 3706:( 3700:) 3696:( 3675:) 3671:( 3653:) 3649:( 3643:) 3639:( 3633:) 3629:( 3603:) 3599:( 3593:) 3587:( 3581:) 3573:( 3562:) 3558:( 3526:( 3520:) 3516:( 3510:) 3506:( 3500:) 3496:( 3490:) 3470:( 3464:) 3458:( 3442:) 3438:( 3432:) 3420:( 3327:) 3321:( 3287:2 3253:2 3186:) 3180:( 3149:) 3145:( 3054:) 3038:) 3032:( 3016:) 3012:( 2976:) 2972:( 2828:) 2824:( 2808:) 2804:( 2762:) 2758:( 2747:) 2743:( 2711:) 2707:( 2701:) 2697:( 2686:) 2682:( 2671:) 2659:( 2653:) 2649:( 2628:) 2624:( 2618:) 2614:( 2608:) 2604:( 2593:) 2589:( 2578:) 2570:( 2564:) 2554:( 2518:) 2514:( 2492:( 2481:) 2477:( 2471:) 2467:( 2461:) 2457:( 2441:) 2437:( 2431:) 2427:( 2421:) 2417:( 2411:) 2407:( 2386:) 2370:( 2364:) 2360:( 2349:) 2337:( 2271:e 2264:t 2257:v 1574:e 1567:t 1560:v 1544:. 1519:. 1515:: 1492:. 1468:: 1460:: 1433:. 1411:: 1384:. 1343:. 1339:: 1316:. 1287:. 1283:: 1260:. 1256:: 1233:. 1209:: 1179:. 1154:. 1126:. 1114:: 1088:. 1058:. 1034:: 1007:. 1003:: 997:9 973:. 946:. 934:: 926:: 876:S 759:2 755:2 739:L 735:S 720:O 718:2 714:2 710:2 706:2 702:2 698:2 694:2 689:H 687:2 683:2 679:2 675:2 671:3 667:2 665:) 663:2 659:2 551:N 479:2 476:S 473:O 467:H 464:6 461:C 363:) 359:( 118:) 78:S 62:S 24:.

Index

Allysine
halicin
Structural formula of R-allicin
Ball and stick model of R-allicin
Preferred IUPAC name
CAS Number
539-86-6
JSmol
Interactive image
Interactive image
Beilstein Reference
ChEBI
CHEBI:28411
ChEMBL
ChEMBL359965
ChemSpider
58548
ECHA InfoCard
100.007.935
Edit this at Wikidata
EC Number
IUPHAR/BPS
2419
KEGG
C07600
MeSH
Allicin
PubChem
65036
UNII

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