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John Kendrew

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In 1947 the MRC agreed to make a research unit for the Study of the Molecular Structure of Biological Systems. The original studies were on the structure of sheep haemoglobin, but when this work had progressed as far as was possible using the resources then available, Kendrew embarked on the study of
51: 520: 598:— comparison of patterns from several crystals; one from the native protein, and others that had been soaked in solutions of heavy metals and had metal ions introduced in different well-defined positions. An electron density map at 6 622:. He became Fellow of the American Society of Biological Chemists in 1967 and honorary member of the International Academy of Science, Munich. In 1974, he succeeded in persuading governments to establish the 656:
Kendrew was married to the former Elizabeth Jarvie (née Gorvin) from 1948 to 1956. Their marriage ended in divorce. Kendrew was subsequently partners with the artist Ruth Harris. He left no survivors.
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Watson, HC; Kendrew, JC (May 1961). "The amino-acid sequence of sperm whale myoglobin. Comparison between the amino-acid sequences of sperm whale myoglobin and of human hæmoglobin".
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on 17 September 1941, he was appointed an honorary wing commander on 8 June 1944, and relinquished his commission on 5 June 1945. He was awarded his PhD after the war in 1949.
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Kendrew, JC; Watson, HC; Strandberg, BE; Dickerson, RE; Phillips, DC; Shore, VC (May 1961). "The amino-acid sequence x-ray methods, and its correlation with chemical data".
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Kendrew, JC; Bodo, G; Dintzis, HM; Parrish, RG; Wyckoff, H; Phillips, DC (March 1958). "A three-dimensional model of the myoglobin molecule obtained by x-ray analysis".
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Kendrew, JC; Dickerson, RE; Strandberg, BE; et al. (February 1960). "Structure of myoglobin: A three-dimensional Fourier synthesis at 2 A. resolution".
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from Peru. Whale myoglobin did give large crystals with clean X-ray diffraction patterns. However, the problem still remained insurmountable, until in 1953
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Ingram, DJ; Kendrew, JC (October 1956). "Orientation of the haem group in myoglobin and its relation to the polypeptide chain direction".
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X-ray studies of certain crystalline proteins : the crystal structure of foetal and adult sheep haemoglobins and of horse myoglobin
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X-ray studies of certain crystalline proteins : the crystal structure of foetal and adult sheep haemoglobins and of horse myoglobin
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During the war years, he became increasingly interested in biochemical problems, and decided to work on the structure of proteins.
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heart, but the crystals thus obtained were too small for X-ray analysis. Kendrew realized that the oxygen-conserving tissue of
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John Kendrew with model of myoglobin in progress. Copyright by the Laboratory of Molecular Biology in Cambridge, England.
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doing research on reaction kinetics, and then became a member of the Air Ministry Research Establishment, working on
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Kendrew, JC; Parris, RG (January 1955). "Imidazole complexes of myoglobin and the position of the haem group".
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Kendrew, JC; Parrish, RG; Marrack, JR; Orlans, ES (November 1954). "The species specificity of myoglobin".
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and became its first director. He was knighted in 1974. From 1974 to 1979, he was a Trustee of the
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could offer a better prospect, and a chance encounter led to his acquiring a large chunk of
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in 1936, as a Major Scholar, graduating in chemistry in 1939. He spent the early months of
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at St John's College in Oxford, officially opened on 16 October 2010, is named after him.
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Investigations of biological structures by X-ray methods : the structure of muscle
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Kendrew, JC (December 1961). "The three-dimensional structure of a protein molecule".
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John Finch; 'A Nobel Fellow on Every Floor', Medical Research Council 2008, 381 pp,
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Kendrew, JC (July 1959). "Structure and function in myoglobin and other proteins".
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Kendrew, JC (October 1962). "The structure of globular proteins".
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After his retirement from EMBL, Kendrew became President of
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Royal Air Force Volunteer Reserve personnel of World War II
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in analysis of the diffraction patterns could be solved by
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The thread of life: an introduction to molecular biology
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Members of the European Molecular Biology Organization
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Foreign associates of the National Academy of Sciences
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Oxford University Press, page on Paul M. Wassarman,
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Biographical Memoirs of Fellows of the Royal Society
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A Place in History: The Biography of John C. Kendrew
614:In 1963, Kendrew became one of the founders of the 555:. Kendrew determined the structure of the protein 514: 420:, art historian. After preparatory school at the 3260: 683:Kendrew, JC (April 1949). "Foetal haemoglobin". 19:For the Industrial Revolution-era designer, see 539:for determining the first atomic structures of 3058: 1502: 357:(24 March 1917 – 23 August 1997) was an 3369:Presidents of the British Science Association 3284:Commanders of the Order of the British Empire 3044: 1644: 1005: 817: 764: 391: 3051: 3037: 1651: 1637: 1585: 1571: 1389: 1387: 636:International Council of Scientific Unions 3394:Royal Air Force personnel of World War II 1407: 1331:(Supplement). 28 July 1944. p. 3562. 1269: 1259: 547:. Their work was done at what is now the 1393: 1351:(Supplement). 6 July 1945. p. 3552. 1341: 1321: 1301: 675: 518: 3364:Presidents of St John's College, Oxford 1384: 1372:(PhD thesis). University of Cambridge. 1361: 1212: 1210: 1208: 1185:(PhD thesis). University of Cambridge. 1140: 1106:Comparative Biochemistry and Physiology 1103: 1058: 923: 682: 616:European Molecular Biology Organization 16:English biochemist and crystallographer 3261: 1611:President of St John's College, Oxford 1482:"The 21st Century: Kendrew Quadrangle" 1239: 1174: 459: 3032: 1632: 1235: 1233: 1231: 624:European Molecular Biology Laboratory 3354:People educated at The Dragon School 3279:Alumni of Trinity College, Cambridge 1394:Stoddart, Charlotte (1 March 2022). 1205: 660:A biography of John Kendrew, titled 1355: 549:MRC Laboratory of Molecular Biology 181:MRC Laboratory of Molecular Biology 13: 3349:People educated at Clifton College 1526: 1228: 467: 14: 3415: 1583:National Portrait Gallery, London 1561: 1503:Wolfgang Saxon (30 August 1997). 1484:. St John's College, Oxford. 2020 1218:"John Kendrew academic genealogy" 1081:10.1038/scientificamerican1261-96 1881: 596:multiple isomorphous replacement 380:to investigate the structure of 292: 272: 49: 3404:Royal Air Force wing commanders 3389:20th-century British biologists 1496: 1474: 1423: 1311:. 7 October 1941. p. 5793. 609: 3379:Trustees of the British Museum 1362:Kendrew, John Cowdery (1949). 1335: 1315: 1295: 1286: 1271:11858/00-001M-0000-0028-EC77-7 1168: 515:Crystal structure of myoglobin 491:In 1947 he became a Fellow of 424:in Oxford, he was educated at 1: 1161: 452:headquarters; commissioned a 3344:Nobel laureates in Chemistry 3319:Fellows of the Royal Society 3304:English molecular biologists 1145:. London: Bell & Hyman. 1118:10.1016/0010-406X(62)90009-9 620:Journal of Molecular Biology 7: 1175:Huxley, Hugh Esmor (1953). 244:Other notable students 10: 3420: 418:Evelyn May Graham Sandburg 18: 3289:British crystallographers 3186: 3179:(Great Britain/Australia) 3155: 3136: 3117: 3093: 3068: 2687: 2388: 2129: 1890: 1879: 1670: 1617: 1608: 1600: 1595: 1579:Portraits of John Kendrew 1409:10.1146/knowable-022822-1 1141:Kendrew, John C. (1966). 559:, which stores oxygen in 432:, 1930–1936. He attended 338: 328: 313: 305: 285: 267: 262: 258: 254: 243: 222: 212: 194: 176: 166: 159: 144:Nobel Prize for Chemistry 136: 122: 112: 102: 83: 57: 48: 30: 2805:Venkatraman Ramakrishnan 2084:Wendell Meredith Stanley 1664:Nobel Prize in Chemistry 527:Kendrew shared the 1962 497:Medical Research Council 392:Education and early life 376:, for their work at the 370:Nobel Prize in Chemistry 345:Sir John Cowdery Kendrew 3314:British Nobel laureates 3309:English Nobel laureates 670:Oxford University Press 117:University of Cambridge 21:John Kendrew (inventor) 3359:Scientists from Oxford 3192:Nobel Prize recipients 3157:Physiology or Medicine 2969:Emmanuelle Charpentier 2957:M. Stanley Whittingham 1928:Hans von Euler-Chelpin 1261:10.1098/rsbm.2001.0018 1240:Holmes, K. C. (2001). 926:Federation Proceedings 524: 472:In 1945 he approached 402:Wilfrid George Kendrew 3384:X-ray crystallography 3324:Structural biologists 3299:English biophysicists 2339:Christian B. Anfinsen 1979:FrĂ©dĂ©ric Joliot-Curie 932:(2, Part 1): 740–51. 676:Selected publications 545:X-ray crystallography 522: 306:Years of service 185:Peterhouse, Cambridge 3001:Karl Barry Sharpless 2498:Dudley R. Herschbach 2323:Luis Federico Leloir 1604:Sir Richard Southern 647:University of Oxford 590:discovered that the 478:Cavendish Laboratory 414:University of Oxford 396:Kendrew was born in 378:Cavendish Laboratory 62:John Cowdery Kendrew 3374:Royal Medal winners 2993:Carolyn R. Bertozzi 2905:Jean-Pierre Sauvage 2642:Jens Christian Skou 2610:F. Sherwood Rowland 2522:Charles J. Pedersen 2486:Herbert A. Hauptman 2179:Vincent du Vigneaud 1796:Richard Willstätter 1680:Jacobus van 't Hoff 1444:1960Natur.185..422K 1073:1961SciAm.205f..96K 1061:Scientific American 1020:1961Natur.190..670W 967:1961Natur.190..666K 885:1958Natur.181..662K 832:1956Natur.178..905I 779:1955Natur.175..206K 726:1954Natur.174..946K 460:Research and career 3294:English biologists 2953:John B. Goodenough 2881:William E. Moerner 2761:Richard R. Schrock 2733:Roderick MacKinnon 2705:K. Barry Sharpless 2530:Johann Deisenhofer 2359:Geoffrey Wilkinson 2355:Ernst Otto Fischer 2279:Robert S. Mulliken 2215:Jaroslav HeyrovskĂ˝ 2163:Hermann Staudinger 1983:Irène Joliot-Curie 1570:on Nobelprize.org 1546:A Place in History 1509:The New York Times 1378:uk.bl.ethos.648050 1348:The London Gazette 1328:The London Gazette 1308:The London Gazette 1199:uk.bl.ethos.604904 651:Kendrew Quadrangle 525: 3256: 3255: 3026: 3025: 3009:Moungi G. Bawendi 2929:Richard Henderson 2773:Roger D. Kornberg 2741:Aaron Ciechanover 2574:Rudolph A. Marcus 2478:Robert Merrifield 2414:Peter D. Mitchell 2187:Cyril Hinshelwood 1948:Friedrich Bergius 1872:Richard Zsigmondy 1788:Theodore Richards 1736:Ernest Rutherford 1627: 1626: 1618:Succeeded by 1596:Academic offices 1538:978-1-84046-940-0 1400:Knowable Magazine 1152:978-0-7135-0618-1 668:was published by 643:St John's College 505:Royal Institution 342: 341: 223:Doctoral students 213:Academic advisors 161:Scientific career 3411: 3334:Knights Bachelor 3194: 3053: 3046: 3039: 3030: 3029: 3019: 3017:Alexei I. Ekimov 3003: 2997:Morten P. Meldal 2987: 2975: 2963: 2947: 2931: 2921:Jacques Dubochet 2915: 2899: 2883: 2867: 2851: 2845:Robert Lefkowitz 2839: 2831: 2815: 2809:Thomas A. Steitz 2799: 2783: 2775: 2767: 2757:Robert H. Grubbs 2751: 2735: 2723: 2707: 2680: 2678:Hideki Shirakawa 2664: 2656: 2644: 2628: 2612: 2596: 2588: 2576: 2568: 2566:Richard R. Ernst 2560: 2552: 2540: 2524: 2508: 2492: 2480: 2472: 2464: 2456: 2444: 2442:Frederick Sanger 2428: 2422:Herbert C. Brown 2416: 2408: 2400: 2398:William Lipscomb 2381: 2369: 2361: 2349: 2333: 2331:Gerhard Herzberg 2325: 2317: 2305: 2297: 2281: 2273: 2265: 2257: 2245: 2233: 2225: 2217: 2209: 2207:Frederick Sanger 2201: 2193: 2191:Nikolay Semyonov 2181: 2173: 2165: 2157: 2145: 2143:Glenn T. 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Watson 3167:(Great Britain) 3151: 3132: 3129:(United States) 3113: 3110:(United States) 3089: 3086:(Great Britain) 3080:(Great Britain) 3064: 3057: 3027: 3022: 3006: 2990: 2981:David MacMillan 2978: 2973:Jennifer Doudna 2966: 2950: 2934: 2918: 2909:Fraser Stoddart 2902: 2893:Paul L. Modrich 2886: 2870: 2854: 2842: 2834: 2829:Ei-ichi Negishi 2821:Richard F. Heck 2818: 2802: 2789:Osamu Shimomura 2786: 2778: 2770: 2754: 2738: 2726: 2710: 2697:William Knowles 2694: 2683: 2674:Alan MacDiarmid 2667: 2659: 2647: 2631: 2626:Richard Smalley 2615: 2602:Paul J. 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Kendrew 1564: 1529: 1527:Further reading 1524: 1523: 1513: 1511: 1501: 1497: 1487: 1485: 1480: 1479: 1475: 1438:(4711): 422–7. 1428: 1424: 1414: 1412: 1392: 1385: 1360: 1356: 1340: 1336: 1320: 1316: 1300: 1296: 1291: 1287: 1238: 1229: 1216: 1215: 1206: 1173: 1169: 1164: 1159: 1153: 1112:(2–4): 249–52. 1014:(4777): 670–2. 879:(4610): 662–6. 826:(4539): 905–6. 773:(4448): 206–7. 720:(4438): 946–9. 678: 672:in March 2020. 612: 517: 486:Joseph Barcroft 470: 468:Crystallography 462: 454:squadron leader 450:Royal Air Force 434:Trinity College 426:Clifton College 394: 348: 300:Royal Air Force 293: 291: 273: 271: 263:Military career 248:James D. Watson 239: 206: 189:Royal Air Force 187: 183: 171:Crystallography 155: 113:Alma mater 107:Clifton College 98: 92: 88: 79: 73: 67: 65: 64: 63: 44: 35: 33: 24: 17: 12: 11: 5: 3417: 3407: 3406: 3401: 3396: 3391: 3386: 3381: 3376: 3371: 3366: 3361: 3356: 3351: 3346: 3341: 3336: 3331: 3326: 3321: 3316: 3311: 3306: 3301: 3296: 3291: 3286: 3281: 3276: 3271: 3254: 3253: 3251: 3250: 3245: 3240: 3235: 3230: 3225: 3220: 3215: 3210: 3205: 3200: 3195: 3187: 3184: 3183: 3181: 3180: 3174: 3168: 3161: 3159: 3153: 3152: 3150: 3149: 3148:(Soviet Union) 3142: 3140: 3134: 3133: 3131: 3130: 3123: 3121: 3115: 3114: 3112: 3111: 3108:John Steinbeck 3104: 3102: 3091: 3090: 3088: 3087: 3081: 3074: 3072: 3066: 3065: 3056: 3055: 3048: 3041: 3033: 3024: 3023: 3021: 3020: 3004: 2988: 2976: 2964: 2948: 2941:Gregory Winter 2937:Frances Arnold 2932: 2916: 2900: 2884: 2868: 2861:Michael Levitt 2857:Martin Karplus 2852: 2840: 2832: 2816: 2800: 2797:Roger Y. Tsien 2793:Martin Chalfie 2784: 2776: 2768: 2752: 2736: 2724: 2708: 2691: 2689: 2685: 2684: 2682: 2681: 2670:Alan J. Heeger 2665: 2657: 2645: 2638:John E. Walker 2629: 2613: 2597: 2589: 2577: 2569: 2561: 2553: 2541: 2538:Hartmut Michel 2525: 2514:Donald J. 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Fenn 2701:Ryoji Noyori 2688:2001–present 2662:Ahmed Zewail 2622:Harold Kroto 2606:Mario Molina 2534:Robert Huber 2506:John Polanyi 2490:Jerome Karle 2426:Georg Wittig 2311:Derek Barton 2303:Lars Onsager 2255:Giulio Natta 2251:Karl Ziegler 2243:John Kendrew 2242: 2011:Richard Kuhn 1936:Hans Fischer 1752:Otto Wallach 1688:Emil Fischer 1609: 1545: 1512:. Retrieved 1508: 1498: 1486:. Retrieved 1476: 1435: 1431: 1425: 1413:. 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685:Endeavour 604:nanometre 572:myoglobin 557:myoglobin 553:Cambridge 533:chemistry 482:Cambridge 438:Cambridge 400:, son of 309:1941–1945 250:(postdoc) 103:Education 97:, England 95:Cambridge 78:, England 1460:18990802 1415:25 March 1280:15124647 1134:14031911 1097:14455128 1044:13783432 999:39469512 991:13752474 946:13672267 909:13517261 864:26921410 856:13369569 811:37160617 803:13235845 750:13214049 705:18144277 600:angstrom 541:proteins 386:proteins 286:Service/ 131:proteins 3138:Physics 1662:of the 1581:at the 1468:4167651 1440:Bibcode 1069:Bibcode 1052:4170869 1016:Bibcode 963:Bibcode 917:4162786 881:Bibcode 828:Bibcode 775:Bibcode 758:4281674 722:Bibcode 645:at the 476:in the 430:Bristol 412:in the 359:English 3007:2023: 2991:2022: 2979:2021: 2967:2020: 2951:2019: 2935:2018: 2919:2017: 2903:2016: 2887:2015: 2871:2014: 2855:2013: 2843:2012: 2835:2011: 2819:2010: 2803:2009: 2787:2008: 2779:2007: 2771:2006: 2755:2005: 2739:2004: 2727:2003: 2711:2002: 2695:2001: 2668:2000: 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Index

John Kendrew (inventor)
CBE
FRS

Oxford
Cambridge
Clifton College
University of Cambridge
Haem
proteins
Nobel Prize for Chemistry
Royal Medal
Crystallography
MRC Laboratory of Molecular Biology
Peterhouse, Cambridge
Royal Air Force
Thesis
X-ray studies of certain crystalline proteins : the crystal structure of foetal and adult sheep haemoglobins and of horse myoglobin
Max Perutz
Hugh Huxley
Lubert Stryer
James D. Watson
United Kingdom
Royal Air Force
Wing Commander
RAFVR
Second World War
CBE
FRS
English

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