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There have been multiple high-profile murder cases that have been alleged to utilize Visine's active ingredient tetrahydrozoline hydrochloride as a poison. In 2018, a South
Carolina nurse was accused of killing her husband by adding Visine to his drinks over a period of three days. In 2019, a North
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for an extended period of time. Because of this risk, Visine usage has been recommended to be limited, unless specified by a doctor. Some formulations of Visine are not advised for contact lens wearers as the decreased blood flow to counter eye redness could further lower oxygen levels to the eye.
374:, offends two women at a bar, prompting one of the women to squirt Visine into his beer bottle without his knowledge. After consuming the drugged liquid, Tucker, and another character, are then depicted as having severe diarrhea.
234:, since stimulation from lubrication can contribute to high pressure within the eye. Certain underlying health conditions that cause eye irritation are not able to be relieved by Visine and require prescription-grade eye drops.
386:
In Season 1, Episode 5 of "Dead Boy
Detectives," a high school girl poisons her boyfriend and another boy using Visine, expecting them to pass out. Instead, they convulse, bleed from their eyes, and die.
357:, uses Visine several times over the course of the film to feign crying. The movie gained notoriety for misrepresenting the effects of Visine consumption, which in actuality can be lethal.
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In addition to its original formulation, Visine is available in several varieties of eye drops for different types of eye irritation. These include formulas with
2123:
852:
648:
Skilling, FC Jr; Weaver, TA; Kato, KP; Ford, JG; Dussia, EM (2005). "Effects of two eye drop products on computer users with subjective ocular discomfort".
536:"Prospective, randomized, controlled comparison of SYSTANE UD eye drops versus VISINE INTENSIV 1% EDO eye drops for the treatment of moderate dry eye"
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353:, is drugged with Visine eye drops, and is depicted as having severe gastrointestinal upset afterwards. The character John Beckwith, portrayed by
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acquired Visine, along with Pfizer's entire consumer healthcare portfolio. The original formulation of Visine includes the active ingredient
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383:, an inmate poisons a fellow inmate using Visine, and the poisoned inmate is depicted as experiencing severe diarrhea shortly after.
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731:
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599:"DailyMed - VISINE ALLERGY EYE RELIEF MULTI-ACTION- naphazoline hydrochloride and pheniramine maleate solution/ drops"
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Carolina paramedic was similarly accused of murdering his wife, with Visine misuse asserted as the probable cause.
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that may cause eye redness to worsen. Prolonged use has been observed to cause blood vessels to be
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Visine has been observed to cause stinging and burning upon application, and has a
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claims that a few drops of Visine will cause harmless but debilitating bouts of
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758:"Nothing funny about so-called 'Visine prank,' says pharmacist | TheRecord.com"
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Oral ingestion of Visine warrants immediate medical attention or a call to a
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Some Visine products are not recommended to be used by patients with
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783:"Tetrahydrozoline poisoning Information | Mount Sinai - New York"
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about Visine inducing severe diarrhea is perpetuated in the film
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for allergy-induced irritation, to moisturizing formulations for
882:"How Visine Eye Drops In The Mouth Can Kill, Here Are Two Cases"
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853:"Death by Visine? Man accused of killing wife via eye drops"
370:. In the movie, the main character Tucker Max, portrayed by
2164:
Steve
Patterson Award for Excellence in Sports Philanthropy
1405:
1268:
476:"Johnson & Johnson Buys Pfizer Unit for $ 16.6 Billion"
301:
116:
148:. Visine was first introduced in 1958 and was acquired by
909:
93:
37:
574:"Visine L.R.: Package Insert / Prescribing Information"
449:"Pfizer Launching Visine Tears for Dry, Irritated Eyes"
647:
128:
122:
110:
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2010 Johnson & Johnson children's product recall
113:
254:. However, symptoms of Visine's active ingredient
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732:"Glaucoma - Diagnosis and treatment - Mayo Clinic"
509:"6 Ways to Fix Your Bloodshot Eyes Without Visine"
405:"Johnson & Johnson buys Pfizer consumer unit"
2186:
624:"Visine Tears Uses, Side Effects & Warnings"
2149:Global Health Innovative Technology Fund (GHIT)
685:"What Happens When You Use Too Many Eye Drops?"
540:Journal of Ocular Pharmacology and Therapeutics
2144:Dr. Paul Janssen Award for Biomedical Research
714:"Why You Should NEVER Use Visine or Cleareyes"
949:
935:
200:. Some Visine products cater specifically to
683:Nelson, Elizabeth Laura (January 14, 2023).
942:
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2200:Drugs developed by Johnson & Johnson
641:
875:
873:
712:Zigler, Dr. Travis (October 14, 2020).
349:the character Sack Lodge, portrayed by
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682:
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431:"Covina Argus from Covina, California"
164:that constricts the eye's superficial
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1922:Emtricitabine/rilpivirine/tenofovir
13:
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294:(hypertension) followed by sudden
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42:Unpackaged Visine bottle from 2014
14:
2211:
903:
850:
474:Saul, Stephanie (June 27, 2006).
1992:Neomycin/polymyxin B/bacitracin
263:Dangerously low body temperature
258:can be severe, and can include:
204:wearers or to those who require
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2159:Robert Wood Johnson Foundation
756:Starr, Katie (July 23, 2013).
616:
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367:I Hope They Serve Beer in Hell
256:tetrahydrozoline hydrochloride
158:tetrahydrozoline hydrochloride
1:
662:10.1016/s1529-1839(05)70254-2
390:
1355:Johnson & Johnson Vision
656:(1). St. Louis, Mo.: 47–54.
237:
7:
1827:Carefree (feminine hygiene)
1758:Ortho Clinical Diagnostics
1299:Ortho-McNeil Pharmaceutical
175:
10:
2216:
534:Jacobi, Christina (2012).
377:In Season 4, Episode 3 of
2111:
2103:Johnson and Johnson Plaza
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1591:Leopoldo Fernández Pujals
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1426:Executives and scientists
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787:Mount Sinai Health System
188:. These formulations use
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75:
67:
57:
47:
35:
26:
1626:Frederick Barnett Kilmer
2139:Chicago Tylenol murders
1616:Robert Wood Johnson III
1284:Janssen Pharmaceuticals
380:Orange Is the New Black
292:Elevated blood pressure
1611:Robert Wood Johnson II
1581:Robert J. Darretta Jr.
287:cessation of breathing
168:to temporarily reduce
2134:Born Rich (2003 film)
2119:2010 DePuy Hip Recall
2047:Rembrandt toothpaste
1521:Robert Wood Johnson I
951:Johnson & Johnson
552:10.1089/jop.2012.0066
323:poison control center
154:Johnson & Johnson
84:Johnson & Johnson
1636:Cynthia A. Maryanoff
1309:Ortho Pharmaceutical
1304:Ortho-McNeil-Janssen
603:dailymed.nlm.nih.gov
283:Difficulty breathing
2195:Ophthalmology drugs
1763:Tasmanian Alkaloids
1561:James Arthur Bayton
1531:Edward Mead Johnson
1257:Innovative medicine
967:Innovative medicine
515:. November 20, 2017
23:
1726:Ronald A. Williams
1686:A. V. Gurava Reddy
1545:Former executives,
1526:James Wood Johnson
1500:Mark A. Weinberger
1475:Marillyn A. Hewson
1470:Jennifer A. Doudna
1443:Board of directors
1435:(Chairman and CEO)
1385:Puma Biotechnology
736:www.mayoclinic.org
480:The New York Times
437:. October 2, 1958.
296:low blood pressure
248:explosive diarrhea
190:active ingredients
152:in 1999. In 2006,
21:
18:Brand of eye drops
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2181:
1739:
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1716:William C. Weldon
1706:George J. Seabury
1631:Robert Q. Marston
1536:George J. Seabury
1490:Mark B. McClellan
1414:
1413:
1368:
1367:
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562:– via NCBI.
455:. January 8, 1999
136:), also known as
99:
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22:Numine, or Visine
2207:
2169:Tooth Protectors
2007:Ortho Tri-Cyclen
1691:Steven Reinemund
1666:William D. Perez
1576:Joan Ganz Cooney
1571:Mary Sue Coleman
1480:Paula A. Johnson
1460:Mary C. Beckerle
1423:
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1360:Mentor (company)
1340:Biosense Webster
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1661:Miguel Patricio
1606:Marillyn Hewson
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1455:Darius Adamczyk
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411:. June 26, 2006
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904:External links
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880:Lee, Bruce Y.
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857:Gaston Gazette
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2174:YODA Project
2027:Prucalopride
2012:Ortho-Cyclen
1912:JNJ-39393406
1902:JNJ-26990990
1897:JNJ-26489112
1808:(US license)
1801:Bapineuzumab
1746:subsidiaries
1721:Ron Williams
1681:Larry Probst
1621:Duda Kertész
1586:Russell Deyo
1556:Koen Andries
1399:Partnerships
1373:Acquisitions
1350:Ethicon Inc.
1250:Subsidiaries
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408:
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372:Matt Czuchry
365:
362:urban legend
359:
343:
342:In the film
341:
332:
329:Criminal use
320:
244:urban legend
241:
220:
212:Side effects
202:contact lens
179:
144:produced by
137:
101:
100:
48:Product type
15:
2037:Rabeprazole
2032:Quisinostat
2017:Ortho-Novum
1917:JNJ-7925476
1907:JNJ-5207852
1872:Doxorubicin
1847:Carisbamate
1842:Eluxadoline
1731:Dick Zimmer
1656:Bill Osborn
1651:Indra Nooyi
1646:Boyd Melson
1641:Sheri McCoy
1485:Hubert Joly
891:January 15,
862:January 15,
836:January 17,
814:January 17,
792:January 15,
741:January 15,
694:January 15,
633:January 15,
608:January 15,
583:January 15,
519:January 14,
493:January 14,
459:January 14,
415:January 14,
355:Owen Wilson
242:A debunked
198:naphazoline
186:eye dryness
170:eye redness
2189:Categories
2154:Innerstate
2087:Tipifarnib
2082:Telaprevir
2022:Pancreatic
1942:Loperamide
1882:Fulranumab
1862:Combantrin
1857:Cladribine
1832:Cetirizine
1390:Technicare
832:. ABC News
810:. Sky News
767:October 6,
391:References
68:Introduced
2129:5B (film)
2096:Buildings
2057:RWJ-51204
1957:Ofloxacin
1927:K-Y Jelly
1887:Helioplex
1837:Doripenem
1781:Abciximab
1335:Acclarent
1294:MorphoSys
1243:Companies
1230:Dermabond
1069:Risperdal
1044:Prezcobix
1034:Invokamet
1024:Intelence
1019:Imbruvica
994:Duragesic
689:Best Life
650:Optometry
628:Drugs.com
578:Drugs.com
488:0362-4331
238:Ingestion
142:eye drops
52:Eye drops
1982:Natrecor
1967:Micronor
1932:Levaquin
1877:Euthymol
1852:Carlumab
1817:Caladryl
1796:Bactidol
1753:LifeScan
1514:Founders
1264:Actelion
1225:Monocryl
1184:Vintivis
1164:Tracleer
1149:Yondelis
1129:Ultracet
1109:Tecvayli
1089:Spravato
1084:Sporanox
1064:Remicade
1059:Razadyne
1049:Prezista
1039:Invokana
989:Ditropan
984:Darzalex
979:Concerta
974:Balversa
718:Eye Love
670:15682562
560:22813209
409:NBC News
307:Seizures
278:vomiting
252:laxative
232:glaucoma
176:Products
138:Vispring
2112:Related
2077:Sylvant
2072:Splenda
2067:Sinutab
2052:Rolaids
1987:Nizoral
1977:Mylicon
1972:Mylanta
1962:Opsumit
1947:McN5652
1937:Lomotil
1812:Benylin
1806:Benecol
1786:Actifed
1380:Abiomed
1328:Medtech
1314:Tibotec
1279:Crucell
1220:Prolene
1210:Ethilon
1198:Medtech
1179:Veletri
1174:Uptravi
1169:Zavesca
1159:Opsumit
1144:Xarelto
1124:Tremfya
1119:Topamax
1114:Terazol
1099:Symtuza
1094:Stelara
1079:Sirturo
1074:Simponi
1054:Procrit
1009:Erleada
1004:Elmiron
999:Edurant
958:Product
311:tremors
227:dilated
90:Website
2062:Savlon
1774:brands
1772:Legacy
1744:Former
1419:People
1215:Vicryl
1205:Acuvue
1189:Vermax
1154:Zytiga
1139:Vermox
1134:Ultram
1104:Talvey
1029:Invega
1014:Haldol
960:brands
886:Forbes
668:
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486:
274:Nausea
150:Pfizer
146:Kenvue
102:Visine
80:Pfizer
62:Kenvue
1867:Doxil
1791:Axert
1274:Cilag
316:Death
58:Owner
1997:o.b.
1406:IBOT
1269:Alza
893:2023
864:2023
838:2020
816:2020
794:2023
769:2017
743:2023
696:2023
666:PMID
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495:2023
484:ISSN
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