301:
226:
42:
486:, sodium pyruvate has been used in many experiments involving cell cultures to provide more energy. In adipocytes it was found that sodium pyruvate promoted increased uptake of insulin-mediated glucose. In the body, one way in which sodium pyruvate provides energy to cells is through pyruvate conversion to acetyl-CoA which then can enter the TCA cycle which produces energy and is linked to other energy producing processes.
52:
29:
428:
489:
Along with having antioxidant properties and energy producing effects, sodium pyruvate has the ability to cross the blood-brain barrier and is used in several studies on brain injury because of these characteristics.
441:
471:, known as pyruvate. It is commonly added to cell culture media as an additional source of energy, but may also have protective effects against
592:
Hwang JS, Kim SY, Jung EH, Kwon MY, Kim KH, Cho H, Han IO (2015-11-19). "Exogenous Sodium
Pyruvate Stimulates Adipogenesis of 3T3-L1 Cells".
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645:"Metabolic and Histologic Effects of Sodium Pyruvate Treatment in the Rat after Cortical Contusion Injury"
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553:"Solution thermodynamics of sodium pyruvate in aqueous glycine solutions at T 298.15-313.15 K"
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509:"The importance of sodium pyruvate in assessing damage produced by hydrogen peroxide"
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Due to pyruvate being an intermediate in many pathways for metabolism including
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Giandomenico AR, Cerniglia GE, Biaglow JE, Stevens CW, Koch CJ (1997).
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Except where otherwise noted, data are given for materials in their
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28:
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Fukushima M, Lee SM, Moro N, Hovda DA, Sutton RL (July 2009).
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479:. and has been confirmed by several independent groups.
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InChI=1S/C3H4O3.Na/c1-2(4)3(5)6;/h1H3,(H,5,6);/q;+1/p-1
334:
InChI=1/C3H4O3.Na/c1-2(4)3(5)6;/h1H3,(H,5,6);/q;+1/p-1
642:
550:
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45:Ball-and-stick model of the pyruvate anion
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557:Journal of the Serbian Chemical Society
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327:Key: DAEPDZWVDSPTHF-UHFFFAOYSA-M
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551:Pandit B, Sarkar A, Sinha B (2016).
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475:. This was reported by Giandomenico
337:Key: DAEPDZWVDSPTHF-REWHXWOFAL
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13:
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40:
14:
718:
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594:Journal of Cellular Biochemistry
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88:α-Ketopropionic acid sodium salt
27:
467:of the conjugate anion form of
422:(at 25 °C , 100 kPa).
91:2-Oxopropanoic acid sodium salt
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94:Pyruvic acid sodium salt
649:Journal of Neurotrauma
76:Sodium 2-oxopropanoate
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661:10.1089/neu.2008.0771
570:10.2298/jsc151031034p
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707:Organic sodium salts
72:Preferred IUPAC name
513:Free Radic Biol Med
412: g·mol
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449:Infobox references
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47:
21:
606:10.1002/jcb.25244
563:(11): 1283–1294.
473:hydrogen peroxide
457:Chemical compound
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280:CompTox Dashboard
144:Interactive image
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55:The sodium cation
16:Chemical compound
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655:(7): 1095–1110.
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374:Chemical formula
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22:Sodium pyruvate
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461:Sodium pyruvate
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420:standard state
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519:(3): 426–34.
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600:(1): 39–48.
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469:pyruvic acid
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358:.C(=O)C(=O)C
184:ChEMBL181886
103:Identifiers
83:Other names
18:
367:Properties
222:100.003.659
164:CHEBI:50144
494:References
484:glycolysis
405:Molar mass
268:POD38AIF08
195:ChemSpider
131:3D model (
110:CAS Number
669:0897-7151
614:0730-2312
579:0352-5139
701:Category
687:19594384
622:26053972
248:23662274
120:113-24-6
678:2848946
630:5100370
535:9214579
442:what is
440: (
410:110.044
235:PubChem
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437:verify
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351:SMILES
175:ChEMBL
66:Names
626:S2CID
477:et al
463:is a
316:InChI
155:ChEBI
133:JSmol
683:PMID
665:ISSN
618:PMID
610:ISSN
575:ISSN
531:PMID
465:salt
259:UNII
204:7931
673:PMC
657:doi
602:doi
598:117
565:doi
521:doi
285:EPA
238:CID
703::
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543:^
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517:23
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511:.
392:Na
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567::
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523::
432:N
398:3
395:O
389:3
386:H
383:3
380:C
287:)
283:(
135:)
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