Knowledge

Serology

Source 📝

261: 203: 123: 308:
surveys are usually used to quantify the proportion of people or animals in a population positive for a specific antibody or the titre or concentrations of an antibody. These surveys are potentially the most direct and informative technique available to infer the dynamics of a population's susceptibility and level of immunity. The authors proposed a
225:. When the antibodies bind to red blood cells that express the corresponding antigen, they cause red blood cells to clump together (agglutinate), which can be identified visually. The person's blood group antibodies can also be identified by adding plasma to cells that express the corresponding antigen and observing the agglutination reactions. 178:(IgG). IgM is produced in high quantities shortly after a person is exposed to the pathogen, and production declines quickly thereafter. IgG is also produced on the first exposure, but not as quickly as IgM. On subsequent exposures, the antibodies produced are primarily IgG, and they remain in circulation for a prolonged period of time. 244:
to ensure that the donor blood is compatible. It involves adding the recipient's plasma to the donor blood cells and observing for agglutination reactions. The direct antiglobulin test is performed to detect if antibodies are bound to red blood cells inside the person's body, which is abnormal and
307:
to determine the prevalence of a disease in a population. Such surveys are sometimes performed by random, anonymous sampling from samples taken for other medical tests or to assess the prevalence of antibodies of a specific organism or protective titre of antibodies in a population. Serological
181:
This affects the interpretation of serology results: a positive result for IgM suggests that a person is currently or recently infected, while a positive result for IgG and negative result for IgM suggests that the person may have been infected or immunized in the past. Antibody testing for
186:) is compared, and a significantly higher amount of IgG in the convalescent specimen suggests infection as opposed to previous exposure. False negative results for antibody testing can occur in people who are 206:
O positive blood type: the patient's red cells are agglutinated by Anti-D (anti-Rh factor) antisera, but not by anti-A and anti-B antisera. The patient's plasma agglutinates type A and B red cells.
170:
The presence of antibodies against a pathogen in a person's blood indicates that they have been exposed to that pathogen. Most serologic tests measure one of two types of antibodies:
182:
infectious diseases is often done in two phases: during the initial illness (acute phase) and after recovery (convalescent phase). The amount of antibody in each specimen (
1714: 1465: 545: 309: 980: 348: 257:. The indirect antiglobulin test is used to screen for antibodies that could cause transfusion reactions and identify certain blood group antigens. 149:, or to detect antigens associated with a pathogen in a person's sample. Serologic tests are especially useful for organisms that are difficult to 1707: 372: 1458: 356: 784: 728: 996: 1700: 283:
Serologic tests can help to diagnose autoimmune disorders by identifying abnormal antibodies directed against a person's own tissues (
1451: 1559: 768: 712: 682: 655: 625: 580: 514: 485: 335:
In a helpful reply entitled "Opportunities and challenges of a World Serum Bank", de Lusignan and Correa observed that the
43: 2074: 2012: 1041: 1509: 1352: 317: 260: 1320: 250: 213:
is typically performed using serologic methods. The antigens on a person's red blood cells, which determine their
1482: 822: 296: 835:"Use of serological surveys to generate key insights into the changing global landscape of infectious disease" 85:
to investigate crime scene evidence. Several methods can be used to detect antibodies and antigens, including
2213: 1969: 1499: 1544: 1524: 404: 2276: 1905: 1867: 1654: 966: 271: 264:
Interpretation of antibody panel used in serology to detect patient antibodies towards the most relevant
246: 102: 2291: 2246: 202: 1797: 1676: 1443: 265: 94: 1947: 1639: 1564: 1013: 502: 312:(or serum bank) and foresaw "associated major methodological developments in serological testing, 1942: 1810: 1775: 1589: 1427: 1034: 90: 38:
in the serum. Such antibodies are typically formed in response to an infection (against a given
2208: 2062: 1957: 1900: 1862: 1514: 477: 343:
and logistical challenges that need to be overcome are the methods of obtaining specimens, how
150: 882:
De Lusignan, Simon; Correa, Ana (2017). "Opportunities and challenges of a World Serum Bank".
758: 617:
Linne & Ringsrud's Clinical Laboratory Science - E-Book: The Basics and Routine Techniques
2286: 2002: 1979: 1964: 1895: 1629: 1519: 1215: 1183: 407:, whose mandate is to carry out a serological survey in a scheme hatched in the midst of the 127: 981:"Prime Minister announces new support for COVID-19 medical research and vaccine development" 732: 469: 2281: 2200: 2057: 2045: 2022: 1952: 1877: 1745: 1649: 1385: 1380: 1337: 1287: 1178: 1157: 1009: 430: 254: 229: 8: 2038: 2033: 1930: 1770: 1644: 1613: 1491: 1342: 1310: 1152: 1120: 98: 1834: 1755: 1579: 1574: 1370: 1362: 1347: 1315: 1295: 1203: 1027: 907: 859: 834: 586: 425: 380: 329: 191: 155: 77:
to certain diseases, and in many other situations, such as determining an individual's
74: 70: 50: 943: 926: 895: 850: 2271: 2140: 2119: 1787: 1782: 1666: 1407: 948: 899: 864: 764: 708: 678: 651: 621: 576: 510: 481: 470: 420: 408: 241: 237: 106: 82: 46: 31: 1692: 967:"WHO set pandemic response back by 2-3 weeks, says doctor on new federal task force" 911: 590: 2230: 1887: 1597: 1569: 1327: 1193: 1079: 938: 891: 854: 846: 818: 568: 344: 187: 175: 171: 2084: 788: 61:
Serological tests are diagnostic methods that are used to identify antibodies and
2223: 2218: 1661: 1504: 1395: 1375: 702: 672: 645: 615: 560: 325: 2089: 572: 2131: 1987: 1760: 1750: 1417: 1412: 1332: 830: 670: 445: 435: 400: 392: 384: 304: 284: 183: 2265: 2174: 2153: 2067: 1992: 1925: 1601: 1300: 1113: 814: 376: 300: 233: 39: 23: 355:
In another helpful reply on the World Serum Bank, the Australian researcher
2179: 2148: 2051: 1740: 1634: 1474: 1402: 1232: 1208: 1198: 1103: 1091: 1084: 952: 903: 868: 826: 783: 727: 368: 313: 210: 138: 1997: 1937: 1872: 1825: 1820: 1815: 1732: 1606: 1536: 1390: 1256: 1137: 1132: 1108: 1003: 388: 364: 321: 190:, as they produce lower amounts of antibodies, and in people who receive 1917: 1857: 1844: 1765: 1724: 1671: 1478: 1422: 1265: 1261: 1237: 1166: 1147: 671:
Connie R. Mahon; Donald C. Lehman; George Manuselis (18 January 2018).
214: 78: 27: 1473: 122: 65:
in a patient's sample. Serological tests may be performed to diagnose
2079: 2007: 1805: 1277: 1220: 1142: 1069: 1050: 756: 66: 145:
are used to determine if a person has antibodies against a specific
2169: 2101: 1852: 1227: 1188: 1173: 1096: 1074: 379:
resources to where they are needed most. A better understanding of
222: 160: 146: 131: 62: 35: 643: 42:), against other foreign proteins (in response, for example, to a 2109: 1554: 1305: 1270: 1250: 1127: 1064: 440: 340: 218: 2114: 1681: 760:
Henry's Clinical Diagnosis and Management by Laboratory Methods
1549: 387:
should inform policy measures including where to concentrate
347:
is acquired in busy practices, and the filling in of gaps in
164: 86: 1019: 757:
Richard A. McPherson; Matthew R. Pincus (6 September 2011).
295:
A 2016 research paper by Metcalf et al., amongst whom were
983:. Justin Trudeau, Prime Minister of Canada. 23 April 2020. 644:
Frank E. Berkowitz; Robert C. Jerris (15 February 2016).
812: 620:. Elsevier Health Sciences. pp. 586–95, 543, 556. 1722: 639: 637: 927:"Opportunities and challenges of a World Serum Bank" 303:, stated that serological surveys are often used by 613: 700: 634: 532:Practical crime scene processing and investigation 881: 16:Scientific study of serum and other bodily fluids 2263: 704:Modern Blood Banking & Transfusion Practices 287:). All people have different immunology graphs. 696: 694: 664: 561:"Immunological Detection and Characterization" 509:(4th ed.). Univ of Texas Medical Branch. 363:Improved serological surveillance would allow 30:. In practice, the term usually refers to the 1708: 1459: 1035: 750: 647:Practical Medical Microbiology for Clinicians 609: 607: 605: 500: 49:), or to one's own proteins (in instances of 763:. Elsevier Health Sciences. pp. 714–5. 691: 677:. Elsevier Health Sciences. pp. 193–4. 674:Textbook of Diagnostic Microbiology - E-Book 53:). In either case, the procedure is simple. 785:American Association for Clinical Chemistry 729:American Association for Clinical Chemistry 567:, Boston, MA: Springer US, pp. 47–62, 546:"Enzyme-linked immunosorbent assay (ELISA)" 1715: 1701: 1466: 1452: 1042: 1028: 602: 1012:at the U.S. National Library of Medicine 942: 858: 650:. John Wiley & Sons. pp. 24–25. 463: 461: 817:; Cutts, Felicity T.; Basta, Nicole E.; 614:Mary Louise Turgeon (10 February 2015). 503:"Principles of Diagnosis: Serodiagnosis" 259: 201: 121: 81:. Serological tests may also be used in 1560:Enzyme multiplied immunoassay technique 806: 701:Denise M Harmening (30 November 2018). 529: 467: 197: 2264: 924: 918: 476:(4th ed.). McGraw Hill. pp.  458: 290: 240:. Crossmatching is performed before a 194:early in the course of the infection. 1696: 1447: 1023: 959: 777: 721: 558: 973: 494: 153:by routine laboratory methods, like 56: 2013:Glycogen phosphorylase isoenzyme BB 875: 385:changing patterns of global weather 13: 1510:Ouchterlony double immunodiffusion 1353:Fluorescence in situ hybridization 505:. In Baron S, et al. (eds.). 14: 2303: 990: 548:. British Society for Immunology. 1321:Oral and maxillofacial pathology 707:. F.A. Davis. pp. 65, 261. 251:hemolytic disease of the newborn 228:Other serologic methods used in 221:that contain antibodies, called 117: 112: 552: 538: 523: 468:Ryan KJ, Ray CG, eds. (2004). 1: 1970:Comprehensive metabolic panel 1500:Chromatin immunoprecipitation 1049: 944:10.1016/S0140-6736(17)30052-1 896:10.1016/S0140-6736(17)30046-6 851:10.1016/S0140-6736(16)30164-7 534:(Second ed.). CRC Press. 452: 278: 245:can occur in conditions like 1545:Chemiluminescent immunoassay 1525:Counterimmunoelectrophoresis 507:Baron's Medical Microbiology 472:Sherris Medical Microbiology 405:COVID-19 Immunity Task Force 236:and the direct and indirect 7: 1906:Thyroid-stimulating hormone 1868:Total iron-binding capacity 1655:Direct fluorescent antibody 573:10.1007/978-1-4899-7448-8_3 414: 272:Blood compatibility testing 247:autoimmune hemolytic anemia 73:, to check if a person has 22:is the scientific study of 10: 2310: 2247:Elevated alpha-fetoprotein 733:"Direct Antiglobulin Test" 565:Viral Infections of Humans 269: 2239: 2199: 2192: 2162: 2139: 2130: 2100: 2021: 1978: 1916: 1886: 1843: 1796: 1731: 1677:Total complement activity 1622: 1588: 1535: 1490: 1361: 1286: 1057: 925:Coates, Karen M. (2017). 559:Atmar, Robert L. (2014), 530:Gardner, Ross M. (2011). 324:in our understanding and 266:human blood group systems 1640:Complement fixation test 1014:Medical Subject Headings 159:(the causative agent of 1776:BUN-to-creatinine ratio 1428:Microbiological culture 1058:Principles of pathology 813:Metcalf, C Jessica E.; 217:, are identified using 2209:Elevated transaminases 1901:Thyroid function tests 1863:Transferrin saturation 1723:Clinical biochemistry 1515:Radial immunodiffusion 501:Washington JA (1996). 397: 353: 320:, which could drive a 275: 207: 134: 103:fluorescent antibodies 2003:Lactate dehydrogenase 1965:Basic metabolic panel 1896:ACTH stimulation test 1630:Diagnostic immunology 1520:Immunoelectrophoresis 1391:Diagnostic immunology 1216:Programmed cell death 1184:Liquefactive necrosis 969:. CBC. 23 April 2020. 361: 337: 318:quantitative analysis 270:Further information: 263: 255:transfusion reactions 205: 128:rapid diagnostic test 125: 2023:Liver function tests 1878:Transferrin receptor 1650:Immunohistochemistry 1386:Medical microbiology 1381:Transfusion medicine 1338:Immunohistochemistry 1288:Anatomical pathology 1179:Coagulative necrosis 1006:Medical Encyclopedia 787:(13 November 2019). 731:(24 December 2019). 431:Medical technologist 383:with respect to the 230:transfusion medicine 198:Transfusion medicine 71:autoimmune illnesses 2039:Serum total protein 2034:Human serum albumin 1645:Immunocytochemistry 1614:Latex fixation test 1492:Immunoprecipitation 1343:Electron microscopy 1311:Molecular pathology 1189:Gangrenous necrosis 1121:Cellular adaptation 821:; Lessler, Justin; 330:infectious diseases 310:World Serology Bank 291:Serological surveys 192:antimicrobial drugs 99:complement-fixation 2277:Clinical pathology 1811:Arterial blood gas 1580:Immunofluorescence 1575:Radiobinding assay 1371:Clinical chemistry 1363:Clinical pathology 1348:Immunofluorescence 1316:Forensic pathology 1296:Surgical pathology 1204:Fibrinoid necrosis 937:(10066): 251–252. 890:(10066): 250–251. 845:(10045): 728–730. 831:Grenfell, Bryan T. 448:, noted serologist 426:Medical laboratory 381:infection dynamics 276: 238:antiglobulin tests 208: 156:Treponema pallidum 135: 105:and more recently 51:autoimmune disease 34:identification of 2292:Immunologic tests 2259: 2258: 2255: 2254: 2188: 2187: 2141:Blood sugar level 2120:Pancreatic lipase 1958:Total cholesterol 1788:Serum osmolal gap 1783:Plasma osmolality 1690: 1689: 1667:Skin allergy test 1441: 1440: 1408:Mass spectrometry 1001: 823:Ferguson, Neil M. 819:Graham, Andrea L. 770:978-1-4557-2684-4 714:978-0-8036-9462-0 684:978-0-323-48212-7 657:978-1-119-06674-3 627:978-0-323-37061-5 582:978-1-4899-7447-1 516:978-0-9631172-1-2 487:978-0-8385-8529-0 421:Forensic serology 409:COVID-19 pandemic 242:blood transfusion 107:chemiluminescence 83:forensic serology 57:Serological tests 47:blood transfusion 2299: 2231:Hyperproteinemia 2197: 2196: 2137: 2136: 1717: 1710: 1703: 1694: 1693: 1598:Hemagglutination 1570:Radioimmunoassay 1468: 1461: 1454: 1445: 1444: 1328:Gross processing 1194:Caseous necrosis 1044: 1037: 1030: 1021: 1020: 999: 985: 984: 977: 971: 970: 963: 957: 956: 946: 922: 916: 915: 879: 873: 872: 862: 827:Burke, Donald S. 810: 804: 803: 801: 799: 793:Lab Tests Online 789:"Autoantibodies" 781: 775: 774: 754: 748: 747: 745: 743: 737:Lab Tests Online 725: 719: 718: 698: 689: 688: 668: 662: 661: 641: 632: 631: 611: 600: 599: 598: 597: 556: 550: 549: 542: 536: 535: 527: 521: 520: 498: 492: 491: 475: 465: 349:patient sampling 345:informed consent 188:immunosuppressed 176:immunoglobulin G 172:immunoglobulin M 2309: 2308: 2302: 2301: 2300: 2298: 2297: 2296: 2262: 2261: 2260: 2251: 2235: 2224:Hypoalbuminemia 2219:Hypoproteinemia 2184: 2158: 2132:Small molecules 2126: 2096: 2017: 1974: 1912: 1882: 1839: 1829: 1792: 1727: 1721: 1691: 1686: 1662:Epitope mapping 1618: 1584: 1531: 1505:Immunodiffusion 1486: 1472: 1442: 1437: 1396:Immunopathology 1376:Hematopathology 1357: 1282: 1053: 1048: 1010:Serologic+Tests 993: 988: 979: 978: 974: 965: 964: 960: 923: 919: 880: 876: 811: 807: 797: 795: 782: 778: 771: 755: 751: 741: 739: 726: 722: 715: 699: 692: 685: 669: 665: 658: 642: 635: 628: 612: 603: 595: 593: 583: 557: 553: 544: 543: 539: 528: 524: 517: 499: 495: 488: 466: 459: 455: 417: 399:In April 2020, 359:declared that: 326:optimum control 305:epidemiologists 293: 281: 274: 200: 143:serologic tests 120: 115: 59: 17: 12: 11: 5: 2307: 2306: 2295: 2294: 2289: 2284: 2279: 2274: 2257: 2256: 2253: 2252: 2250: 2249: 2243: 2241: 2237: 2236: 2234: 2233: 2228: 2227: 2226: 2216: 2211: 2205: 2203: 2194: 2190: 2189: 2186: 2185: 2183: 2182: 2177: 2172: 2166: 2164: 2160: 2159: 2157: 2156: 2151: 2145: 2143: 2134: 2128: 2127: 2125: 2124: 2123: 2122: 2112: 2106: 2104: 2098: 2097: 2095: 2094: 2093: 2092: 2087: 2077: 2072: 2071: 2070: 2065: 2060: 2048: 2043: 2042: 2041: 2036: 2027: 2025: 2019: 2018: 2016: 2015: 2010: 2005: 2000: 1995: 1990: 1988:Cardiac marker 1984: 1982: 1980:Cardiovascular 1976: 1975: 1973: 1972: 1967: 1962: 1961: 1960: 1955: 1950: 1945: 1935: 1934: 1933: 1931:Hemoglobin A1c 1922: 1920: 1914: 1913: 1911: 1910: 1909: 1908: 1898: 1892: 1890: 1884: 1883: 1881: 1880: 1875: 1870: 1865: 1860: 1855: 1849: 1847: 1841: 1840: 1838: 1837: 1832: 1827: 1823: 1818: 1813: 1808: 1802: 1800: 1794: 1793: 1791: 1790: 1785: 1780: 1779: 1778: 1773: 1768: 1761:Renal function 1758: 1753: 1748: 1743: 1737: 1735: 1729: 1728: 1720: 1719: 1712: 1705: 1697: 1688: 1687: 1685: 1684: 1679: 1674: 1669: 1664: 1659: 1658: 1657: 1647: 1642: 1637: 1632: 1626: 1624: 1620: 1619: 1617: 1616: 1611: 1610: 1609: 1594: 1592: 1586: 1585: 1583: 1582: 1577: 1572: 1567: 1562: 1557: 1552: 1547: 1541: 1539: 1533: 1532: 1530: 1529: 1528: 1527: 1522: 1517: 1512: 1502: 1496: 1494: 1488: 1487: 1471: 1470: 1463: 1456: 1448: 1439: 1438: 1436: 1435: 1430: 1425: 1420: 1418:Flow cytometry 1415: 1413:Chromatography 1410: 1405: 1399: 1398: 1393: 1388: 1383: 1378: 1373: 1367: 1365: 1359: 1358: 1356: 1355: 1350: 1345: 1340: 1335: 1333:Histopathology 1330: 1324: 1323: 1318: 1313: 1308: 1303: 1298: 1292: 1290: 1284: 1283: 1281: 1280: 1275: 1274: 1273: 1268: 1259: 1247: 1241: 1240: 1235: 1230: 1225: 1224: 1223: 1213: 1212: 1211: 1206: 1201: 1196: 1191: 1186: 1181: 1171: 1169: 1163: 1162: 1161: 1160: 1155: 1145: 1140: 1135: 1130: 1125: 1123: 1117: 1116: 1111: 1106: 1101: 1100: 1099: 1089: 1088: 1087: 1082: 1077: 1072: 1061: 1059: 1055: 1054: 1047: 1046: 1039: 1032: 1024: 1018: 1017: 1007: 992: 991:External links 989: 987: 986: 972: 958: 917: 874: 815:Farrar, Jeremy 805: 776: 769: 749: 720: 713: 690: 683: 663: 656: 633: 626: 601: 581: 551: 537: 522: 515: 493: 486: 456: 454: 451: 450: 449: 446:Geoffrey Tovey 443: 438: 436:Seroconversion 433: 428: 423: 416: 413: 401:Justin Trudeau 393:insect control 373:policy writers 292: 289: 285:autoantibodies 280: 277: 199: 196: 184:antibody titer 119: 116: 114: 111: 58: 55: 15: 9: 6: 4: 3: 2: 2305: 2304: 2293: 2290: 2288: 2285: 2283: 2280: 2278: 2275: 2273: 2270: 2269: 2267: 2248: 2245: 2244: 2242: 2238: 2232: 2229: 2225: 2222: 2221: 2220: 2217: 2215: 2212: 2210: 2207: 2206: 2204: 2202: 2198: 2195: 2191: 2181: 2178: 2176: 2175:Hyperuricemia 2173: 2171: 2168: 2167: 2165: 2161: 2155: 2154:Hyperglycemia 2152: 2150: 2147: 2146: 2144: 2142: 2138: 2135: 2133: 2129: 2121: 2118: 2117: 2116: 2113: 2111: 2108: 2107: 2105: 2103: 2099: 2091: 2088: 2086: 2083: 2082: 2081: 2078: 2076: 2073: 2069: 2068:AST/ALT ratio 2066: 2064: 2061: 2059: 2056: 2055: 2054: 2053: 2052:transaminases 2049: 2047: 2044: 2040: 2037: 2035: 2032: 2031: 2029: 2028: 2026: 2024: 2020: 2014: 2011: 2009: 2006: 2004: 2001: 1999: 1996: 1994: 1993:Troponin test 1991: 1989: 1986: 1985: 1983: 1981: 1977: 1971: 1968: 1966: 1963: 1959: 1956: 1954: 1953:Triglycerides 1951: 1949: 1946: 1944: 1941: 1940: 1939: 1936: 1932: 1929: 1928: 1927: 1926:Blood glucose 1924: 1923: 1921: 1919: 1915: 1907: 1904: 1903: 1902: 1899: 1897: 1894: 1893: 1891: 1889: 1885: 1879: 1876: 1874: 1871: 1869: 1866: 1864: 1861: 1859: 1856: 1854: 1851: 1850: 1848: 1846: 1842: 1836: 1833: 1831: 1824: 1822: 1819: 1817: 1814: 1812: 1809: 1807: 1804: 1803: 1801: 1799: 1795: 1789: 1786: 1784: 1781: 1777: 1774: 1772: 1769: 1767: 1764: 1763: 1762: 1759: 1757: 1754: 1752: 1749: 1747: 1744: 1742: 1739: 1738: 1736: 1734: 1730: 1726: 1718: 1713: 1711: 1706: 1704: 1699: 1698: 1695: 1683: 1680: 1678: 1675: 1673: 1670: 1668: 1665: 1663: 1660: 1656: 1653: 1652: 1651: 1648: 1646: 1643: 1641: 1638: 1636: 1633: 1631: 1628: 1627: 1625: 1621: 1615: 1612: 1608: 1605: 1604: 1603: 1602:Hemagglutinin 1599: 1596: 1595: 1593: 1591: 1590:Agglutination 1587: 1581: 1578: 1576: 1573: 1571: 1568: 1566: 1563: 1561: 1558: 1556: 1553: 1551: 1548: 1546: 1543: 1542: 1540: 1538: 1534: 1526: 1523: 1521: 1518: 1516: 1513: 1511: 1508: 1507: 1506: 1503: 1501: 1498: 1497: 1495: 1493: 1489: 1484: 1480: 1476: 1475:Medical tests 1469: 1464: 1462: 1457: 1455: 1450: 1449: 1446: 1434: 1431: 1429: 1426: 1424: 1421: 1419: 1416: 1414: 1411: 1409: 1406: 1404: 1401: 1400: 1397: 1394: 1392: 1389: 1387: 1384: 1382: 1379: 1377: 1374: 1372: 1369: 1368: 1366: 1364: 1360: 1354: 1351: 1349: 1346: 1344: 1341: 1339: 1336: 1334: 1331: 1329: 1326: 1325: 1322: 1319: 1317: 1314: 1312: 1309: 1307: 1304: 1302: 1301:Cytopathology 1299: 1297: 1294: 1293: 1291: 1289: 1285: 1279: 1276: 1272: 1269: 1267: 1263: 1260: 1258: 1255: 1254: 1253: 1252: 1248: 1246: 1245:Accumulations 1243: 1242: 1239: 1236: 1234: 1231: 1229: 1226: 1222: 1219: 1218: 1217: 1214: 1210: 1207: 1205: 1202: 1200: 1197: 1195: 1192: 1190: 1187: 1185: 1182: 1180: 1177: 1176: 1175: 1172: 1170: 1168: 1165: 1164: 1159: 1156: 1154: 1151: 1150: 1149: 1146: 1144: 1141: 1139: 1136: 1134: 1131: 1129: 1126: 1124: 1122: 1119: 1118: 1115: 1114:Wound healing 1112: 1110: 1107: 1105: 1102: 1098: 1095: 1094: 1093: 1090: 1086: 1083: 1081: 1078: 1076: 1073: 1071: 1068: 1067: 1066: 1063: 1062: 1060: 1056: 1052: 1045: 1040: 1038: 1033: 1031: 1026: 1025: 1022: 1015: 1011: 1008: 1005: 998: 995: 994: 982: 976: 968: 962: 954: 950: 945: 940: 936: 932: 928: 921: 913: 909: 905: 901: 897: 893: 889: 885: 878: 870: 866: 861: 856: 852: 848: 844: 840: 836: 832: 828: 824: 820: 816: 809: 794: 790: 786: 780: 772: 766: 762: 761: 753: 738: 734: 730: 724: 716: 710: 706: 705: 697: 695: 686: 680: 676: 675: 667: 659: 653: 649: 648: 640: 638: 629: 623: 619: 618: 610: 608: 606: 592: 588: 584: 578: 574: 570: 566: 562: 555: 547: 541: 533: 526: 518: 512: 508: 504: 497: 489: 483: 479: 474: 473: 464: 462: 457: 447: 444: 442: 439: 437: 434: 432: 429: 427: 424: 422: 419: 418: 412: 410: 406: 402: 396: 394: 390: 386: 382: 378: 377:public health 374: 370: 366: 360: 358: 352: 350: 346: 342: 336: 333: 331: 327: 323: 319: 315: 311: 306: 302: 301:Jeremy Farrar 298: 297:Neil Ferguson 288: 286: 273: 267: 262: 258: 256: 252: 248: 243: 239: 235: 234:crossmatching 231: 226: 224: 220: 216: 212: 204: 195: 193: 189: 185: 179: 177: 173: 168: 166: 162: 158: 157: 152: 148: 144: 140: 133: 129: 124: 110: 108: 104: 100: 96: 95:precipitation 92: 91:agglutination 88: 84: 80: 76: 72: 68: 64: 54: 52: 48: 45: 41: 40:microorganism 37: 33: 29: 25: 21: 2287:Epidemiology 2214:Elevated ALP 2180:Hypouricemia 2149:Hypoglycemia 2085:Unconjugated 2050: 1733:Electrolytes 1635:Nephelometry 1485:86000–86849) 1432: 1403:Enzyme assay 1249: 1244: 1233:Karyorrhexis 1209:Myocytolysis 1199:Fat necrosis 1104:Inflammation 1092:Hemodynamics 1085:Pathogenesis 975: 961: 934: 930: 920: 887: 883: 877: 842: 838: 808: 796:. Retrieved 792: 779: 759: 752: 740:. Retrieved 736: 723: 703: 673: 666: 646: 616: 594:, retrieved 564: 554: 540: 531: 525: 506: 496: 471: 398: 391:efforts and 369:aid agencies 362: 357:Karen Coates 354: 338: 334: 314:study design 294: 282: 227: 211:Blood typing 209: 180: 169: 154: 142: 139:microbiology 136: 126:IgG and IgM 118:Microbiology 113:Applications 60: 19: 18: 2282:Blood tests 2163:Nitrogenous 1998:CPK-MB test 1938:Lipid panel 1873:Transferrin 1821:Bicarbonate 1816:Base excess 1725:blood tests 1607:Coombs test 1537:Immunoassay 1257:Hemosiderin 1138:Hyperplasia 1133:Hypertrophy 1109:Cell damage 1004:MedlinePlus 403:formed the 389:vaccination 365:governments 322:step change 28:body fluids 2266:Categories 2090:Conjugated 1918:Metabolism 1858:Serum iron 1845:Iron tests 1766:Creatinine 1672:Patch test 1479:immunology 1423:Blood bank 1266:Lipofuscin 1262:Lipochrome 1238:Karyolysis 1167:Cell death 1148:Metaplasia 1000:(archived) 931:The Lancet 884:The Lancet 839:The Lancet 596:2021-06-13 453:References 375:to direct 339:principal 279:Immunology 215:blood type 174:(IgM) and 79:blood type 67:infections 44:mismatched 36:antibodies 32:diagnostic 26:and other 2080:Bilirubin 2030:Proteins 2008:Myoglobin 1806:Anion gap 1798:Acid-base 1746:Potassium 1565:RAST test 1278:Steatosis 1221:Apoptosis 1158:Glandular 1143:Dysplasia 1075:Neoplasia 1070:Infection 1051:Pathology 395:measures. 2272:Serology 2193:Proteins 2170:Azotemia 2102:Pancreas 1888:Hormones 1853:Ferritin 1751:Chloride 1477:used in 1433:Serology 1228:Pyknosis 1174:Necrosis 1153:Squamous 1097:Ischemia 997:Serology 953:28118912 912:42914918 904:28118910 869:27059886 833:(2016). 798:24 April 742:24 April 591:68212270 415:See also 232:include 223:antisera 219:reagents 161:syphilis 147:pathogen 132:COVID-19 75:immunity 63:antigens 20:Serology 2110:Amylase 1835:Lactate 1830:content 1756:Calcium 1555:ELISpot 1306:Autopsy 1271:Melanin 1251:pigment 1128:Atrophy 1065:Disease 860:5678936 441:Serovar 341:ethical 165:viruses 151:culture 2115:Lipase 1741:Sodium 1682:MELISA 1016:(MeSH) 951:  910:  902:  867:  857:  767:  711:  681:  654:  624:  589:  579:  513:  484:  371:, and 316:, and 163:), or 101:, and 2240:Other 1623:Other 1550:ELISA 1080:Cause 908:S2CID 587:S2CID 87:ELISA 24:serum 1771:Urea 949:PMID 900:PMID 865:PMID 800:2020 765:ISBN 744:2020 709:ISBN 679:ISBN 652:ISBN 622:ISBN 577:ISBN 511:ISBN 482:ISBN 480:–9. 299:and 253:and 130:for 69:and 2201:LFT 2075:GGT 2063:AST 2058:ALT 2046:ALP 1948:HDL 1943:LDL 1483:CPT 939:doi 935:389 892:doi 888:389 855:PMC 847:doi 843:388 569:doi 478:247 332:." 328:of 137:In 2268:: 1826:CO 1002:– 947:. 933:. 929:. 906:. 898:. 886:. 863:. 853:. 841:. 837:. 829:; 825:; 791:. 735:. 693:^ 636:^ 604:^ 585:, 575:, 563:, 460:^ 411:. 367:, 268:. 249:, 167:. 141:, 109:. 97:, 93:, 89:, 1828:2 1716:e 1709:t 1702:v 1600:/ 1481:( 1467:e 1460:t 1453:v 1264:/ 1043:e 1036:t 1029:v 955:. 941:: 914:. 894:: 871:. 849:: 802:. 773:. 746:. 717:. 687:. 660:. 630:. 571:: 519:. 490:. 351:.

Index

serum
body fluids
diagnostic
antibodies
microorganism
mismatched
blood transfusion
autoimmune disease
antigens
infections
autoimmune illnesses
immunity
blood type
forensic serology
ELISA
agglutination
precipitation
complement-fixation
fluorescent antibodies
chemiluminescence

rapid diagnostic test
COVID-19
microbiology
pathogen
culture
Treponema pallidum
syphilis
viruses
immunoglobulin M

Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.