239:
144:
404:
27:
455:
409:
408:
407:
641:
Gulston, Melanie; Knowland, John (1999). "Illumination of human keratinocytes in the presence of the sunscreen ingredient
Padimate-O and through an SPF-15 sunscreen reduces direct photodamage to DNA but increases strand breaks".
782:
Kerr, Caroline (1998). "The effects of two UVB radiation-absorbing sunscreens on UV radiation-induced carcinogenesis, suppression of the contact hypersensitivity response and histological changes in the hairless mouse".
561:
studies conducted in hairless mice following topical application of padimate O have demonstrated no carcinogenic effects and that padimate O reduces the number of and delays the appearance of UV-induced skin tumors.
712:
Bissett, Donald L.; McBride, James F.; Hannon, Daniel P.; Patrick, Larry F. (1991). "Time-dependent decrease in sunscreen protection against chronic photodamage in UVB-irradiated hairless mouse skin".
515:
410:
468:
747:
Bissett, Donald L; McBride, James F (1996). "Synergistic topical photoprotection by a combination of the iron chelator 2-furildioxime and sunscreen".
598:
Knowland, John; McKenzie, Edward A; McHugh, Peter J; Cridland, Nigel A (1993). "Sunlight-induced mutagenicity of a common sunscreen ingredient".
432:
836:
288:
898:
425:
101:
552:, which is considered photocarcinogenic in rats and mice. These findings suggest that padimate O might also be photocarcinogenic.
518:. Other names for padimate O include 2-ethylhexyl 4-dimethylaminobenzoate, Escalol 507, octyldimethyl PABA, and OD-PABA.
677:
Kligman, Lorraine H.; Akin, Frank J.; Kligman, Albert M. (1980). "Sunscreens prevent ultraviolet photocarcinogenesis".
463:
829:
253:
475:
1100:
418:
814:
1105:
850:
822:
196:
139:
217:
1010:
234:
262:
InChI=1S/C17H27NO2/c1-5-7-8-14(6-2)13-20-17(19)15-9-11-16(12-10-15)18(3)4/h9-12,14H,5-8,13H2,1-4H3
1072:
272:
InChI=1/C17H27NO2/c1-5-7-8-14(6-2)13-20-17(19)15-9-11-16(12-10-15)18(3)4/h9-12,14H,5-8,13H2,1-4H3
954:
893:
577:
507:
39:
979:
908:
205:
121:
77:
534:
by UV-B. However, the thus-excited padimate O molecule may then react with DNA to produce
8:
939:
929:
549:
535:
495:
238:
143:
67:
623:
796:
760:
690:
655:
800:
764:
729:
725:
694:
659:
615:
611:
531:
627:
1048:
959:
792:
756:
721:
686:
651:
607:
491:
311:
185:
1068:
974:
844:
1000:
548:
of padimate O. The photobiological properties of padimate O resemble those of
511:
446:
1094:
1030:
375:
365:
132:
1038:
1015:
1005:
995:
663:
804:
768:
733:
698:
619:
431:
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1020:
863:
527:
417:
1053:
1025:
969:
949:
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888:
571:
424:
342:
112:
924:
845:
785:
Mutation
Research/Fundamental and Molecular Mechanisms of Mutagenesis
499:
445:
Except where otherwise noted, data are given for materials in their
934:
903:
540:
390:
160:
644:
Mutation
Research/Genetic Toxicology and Environmental Mutagenesis
100:
1080:
557:
545:
355:
172:
544:
yeast study conducted in 1993 demonstrated the sunlight-induced
597:
503:
90:
26:
498:(4-aminobenzoic acid) that is used as an ingredient in some
222:
711:
151:
899:
Diethylamino hydroxybenzoyl hexyl benzoate (Uvinul A Plus)
16:
Water-insoluble oily ingredient used in some sunscreens
714:
502:. This yellowish water-insoluble oily liquid is an
538:, similar to the effects of ionizing radiation. An
676:
1092:
184:
640:
406:
76:
970:Phenylbenzimidazole sulfonic acid (Ensulizole)
749:Journal of the American Academy of Dermatology
746:
679:Journal of the American Academy of Dermatology
830:
634:
591:
837:
823:
237:
142:
120:
204:
950:4-Methylbenzylidene camphor (Enzacamene)
894:Bisdisulizole disodium (Neo Heliopan AP)
233:
1093:
1039:Bisoctrizole (Tinosorb M / Eversorb M)
873:Chemical agents unless otherwise noted
494:related to the water-soluble compound
380:362 °C (684 °F; 635 K)
133:
43:2-ethylhexyl 4-(dimethylamino)benzoate
1011:Drometrizole trisiloxane (Mexoryl XL)
818:
265:Key: WYWZRNAHINYAEF-UHFFFAOYSA-N
781:
955:Octyl methoxycinnamate (Octinoxate)
275:Key: WYWZRNAHINYAEF-UHFFFAOYAL
175:
159:
13:
940:Ethylhexyl triazone (Uvinul T 150)
402:
14:
1117:
574:, a related sunscreen ingredient
453:
329:
323:
25:
521:
449:(at 25 °C , 100 kPa).
296:O=C(OCC(CC)CCCC)c1ccc(N(C)C)cc1
775:
740:
705:
670:
332:
317:
1:
960:Octyl salicylate (Octisalate)
797:10.1016/S0027-5107(98)00188-2
761:10.1016/S0190-9622(96)90677-5
691:10.1016/S0190-9622(80)80221-0
656:10.1016/S1383-5718(99)00091-1
584:
975:Polysilicone-15 (Parsol SLX)
726:10.1016/1011-1344(91)80169-I
612:10.1016/0014-5793(93)80141-G
7:
1036:Hybrid (chemical/physical):
565:
10:
1122:
1066:
1016:Iscotrizinol (Uvasorb HEB)
930:4-Aminobenzoic acid (PABA)
51:2-ethylhexyl dimethyl PABA
1064:
1026:Oxybenzone (Eusolex 4360)
996:Bemotrizinol (Tinosorb S)
988:
917:
881:
859:
530:rays, thereby preventing
516:dimethylaminobenzoic acid
443:
384:
304:
284:
249:
60:
48:
38:
33:
24:
965:Padimate O (Escalol 507)
889:Avobenzone (Parsol 1789)
1073:Sun protective clothing
1101:4-Aminobenzoate esters
413:
904:Ecamsule (Mexoryl SX)
578:Sunscreen controversy
412:
980:Trolamine salicylate
909:Menthyl anthranilate
395:(fire diamond)
1106:Sunscreening agents
846:Sunscreening agents
536:indirect DNA damage
526:Padimate O absorbs
350: g·mol
21:
1001:Benzophenones 1–12
555:However, multiple
476:Infobox references
414:
19:
1088:
1087:
853:or other agencies
532:direct DNA damage
484:Chemical compound
482:
481:
218:CompTox Dashboard
102:Interactive image
1113:
1049:Titanium dioxide
854:
849:approved by the
839:
832:
825:
816:
815:
809:
808:
779:
773:
772:
744:
738:
737:
720:(3–4): 323–334.
709:
703:
702:
674:
668:
667:
638:
632:
631:
595:
550:Michler's ketone
492:organic compound
466:
460:
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349:
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312:Chemical formula
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29:
22:
18:
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1112:
1111:
1110:
1091:
1090:
1089:
1084:
1083:
1069:Photoprotection
1060:
989:UVA+UVB filters
984:
913:
877:
869:UVB: 315–290 nm
855:
848:
843:
813:
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512:2-ethylhexanol
506:formed by the
483:
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479:
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452:
451:
447:standard state
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1099:
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1082:
1078:
1074:
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1063:
1055:
1052:
1050:
1047:
1046:
1045:
1042:
1040:
1037:
1034:
1032:
1031:Sulisobenzone
1029:
1027:
1024:
1022:
1019:
1017:
1014:
1012:
1009:
1007:
1004:
1002:
999:
997:
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902:
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890:
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886:
884:
880:
874:
871:
868:
866:A: 400–315 nm
865:
862:
861:
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852:
847:
840:
835:
833:
828:
826:
821:
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673:
665:
661:
657:
653:
649:
645:
637:
629:
625:
621:
617:
613:
609:
606:(3): 309–13.
605:
601:
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579:
576:
573:
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569:
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470:
465:
448:
442:
435:
428:
421:
397:
394:
393:
389:
388:
383:
379:
377:
376:Boiling point
374:
373:
369:
367:
366:Melting point
364:
363:
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353:
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344:
341:
340:
316:
313:
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235:DTXSID7029320
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150:
149:
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141:
138:
136:
134:ECHA InfoCard
131:
130:
123:
119:
118:
116:
114:
111:
110:
103:
99:
98:
96:
92:
87:
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72:
69:
65:
64:
59:
47:
41:
37:
32:
28:
23:
1043:
1035:
1006:Dioxybenzone
964:
872:
791:(1): 161–4.
788:
784:
777:
755:(4): 546–9.
752:
748:
742:
717:
713:
707:
682:
678:
672:
650:(1): 49–60.
647:
643:
636:
603:
600:FEBS Letters
599:
593:
556:
554:
546:mutagenicity
539:
525:
522:Photobiology
508:condensation
487:
486:
391:
61:Identifiers
49:Other names
1077:Sun tanning
1021:Octocrylene
918:UVB filters
882:UVA filters
685:(1): 30–5.
528:ultraviolet
305:Properties
140:100.040.248
53:Escalol 507
20:Padimate O
1095:Categories
1067:See also:
1054:Zinc oxide
945:Homosalate
585:References
572:Padimate A
500:sunscreens
488:Padimate O
370:<25 °C
360:0.99 g/cm
343:Molar mass
206:Z11006CMUZ
113:ChemSpider
89:3D model (
78:21245-02-3
68:CAS Number
40:IUPAC name
1044:Physical:
925:Amiloxate
935:Cinoxate
664:10477339
628:23853321
566:See also
541:in vitro
392:NFPA 704
385:Hazards
1081:Sunburn
805:9920441
769:8859281
734:1919875
699:6967495
620:8405372
558:in vivo
469:what is
467: (
356:Density
348:277.408
173:PubChem
55:Sundown
1079:, and
851:US FDA
803:
767:
732:
697:
662:
626:
618:
490:is an
464:verify
461:
289:SMILES
161:D05335
34:Names
624:S2CID
514:with
504:ester
254:InChI
186:30541
122:28343
91:JSmol
801:PMID
765:PMID
730:PMID
695:PMID
660:PMID
616:PMID
496:PABA
197:UNII
152:KEGG
793:doi
789:422
757:doi
722:doi
687:doi
652:doi
648:444
608:doi
604:324
510:of
223:EPA
176:CID
1097::
1075:,
1071:,
864:UV
799:.
787:.
763:.
753:35
751:.
728:.
716:.
693:.
681:.
658:.
646:.
622:.
614:.
602:.
327:27
321:17
838:e
831:t
824:v
807:.
795::
771:.
759::
736:.
724::
718:9
701:.
689::
683:3
666:.
654::
630:.
610::
580:.
459:Y
433:0
426:1
419:1
336:2
333:O
330:N
324:H
318:C
225:)
221:(
93:)
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