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are minimally consumed. Some nutritional genomics studies have pointed towards the
Mediterranean diet to be most nutritionally beneficial. It has been positively linked towards decreased mortality by providing protective agents against metabolic diseases, cardiovascular disease and several types of cancer. These benefits have been attributed to the abundance of dietary compounds present in Mediterranean staples. Examples of this include
1166:
149:, metabolic syndrome) can be identified. Nutrigenomics can help with personalized health and nutrition intake by assessing individuals and make specific nutritional requirements. The focus is in the prevention and the correction of specific genetic disorders. Examples of genetic related disorders that improve with nutritional correction are obesity,
61:. Each of these subcategories explain some aspect of how genes react to nutrients and express specific phenotypes, like disease risk. There are several applications for nutritional genomics, for example how much nutritional intervention and therapy can successfully be used for disease prevention and treatment.
73:
which results from a lack of vitamin C. As other diseases closely related to diet (but not deficiency), such as obesity, became more prevalent, nutritional science expanded to cover these topics as well. Nutritional research typically focuses on preventative measure, trying to identify what nutrients
182:
Obesity is one of the most widely studied topics in nutritional genomics. Due to genetic variations among individuals, each person could respond to diet differently. By exploring the interaction between dietary pattern and genetic factors, the field aims to suggest dietary changes that could prevent
194:
SNP rs512535 is another diet-related variation; the A/G heterozygous genotype was found to have association with obesity (in terms of BMI and waist circumference) and for individuals with habitual high fat diet (>35% of energy intake), while individuals with GG homozygous genotype are likely to
101:
refers to naturally occurring foods native to Greece, Italy and Spain before globalization of food products in the 20th century. The diet includes relatively high consumption of fruit, vegetables, olive oil, legumes, whole grains and moderate amounts of red wine. Foods with increased fat and dairy
623:
Shannon, O. M., Ashor, A. W., Scialo, F., Saretzki, G., Martin-Ruiz, C., Lara, J., Matu, J., Griffiths, A., Robinson, N., LillĂ , L., Stevenson, E., Stephan, B. C. M., Minihane, A. M., Siervo, M., & Mathers, J. C. (2021). Mediterranean diet and the hallmarks of ageing. European journal of
173:
loci. These loci differences result in individualized reactions to the consumption of lipids. Some people experience increased weight gain and greater risk of CHD whereas others with different loci do not. Research has shown a direct correlation between the decrease risk of CHD and the decrease
328:
Fenech, Michael; El-Sohemy, Ahmed; Cahill, Leah; Ferguson, Lynnette R.; French, Tapaeru-Ariki C.; Tai, E. Shyong; Milner, John; Koh, Woon-Puay; Xie, Lin; Zucker, Michelle; Buckley, Michael; Cosgrove, Leah; Lockett, Trevor; Fung, Kim Y.C.; Head, Richard (2011).
81:, a disease whose most distinguishing factor is insatiable appetite, has been specifically linked to an epigenetic pattern in which the paternal copy in the chromosomal region is erroneously deleted, and the maternal loci is inactivated by over
128:
in extra virgin olive oil. It has been suggested that each of these allegedly bioactive compounds, along with several others, interacts with the body's cellular and molecular function, gene expression and epigenome to prevent
636:
Divella R, Daniele A, Savino E, Paradiso A. Anticancer
Effects of Nutraceuticals in the Mediterranean Diet: An Epigenetic Diet Model. Cancer Genomics Proteomics. 2020 Jul-Aug;17(4):335-350. doi: 10.21873/cgp.20193.
1101:
203:
Phenylketonuria, otherwise known as PKU, is an uncommon autosomal recessive metabolic disorder that takes effect postpartum but the debilitating symptoms can be reversed with nutritional intervention.
169:
Genes tied to nutrition manifest themselves through the body's sensitivity to food. In studies about CHD, there is a relationship between the disease and the presence of two alleles found at E and B
49:, as well as single gene/single food compound relationships. Nutritional genomics or Nutrigenomics is the relation between food and inherited genes, it was first expressed in 2001.
530:
69:
Nutritional science originally emerged as a field that studied individuals lacking certain nutrients and the subsequent effects, such as the disease
153:(CHD), hypertension and diabetes mellitus type 1. Genetic disorders that can often be prevented by proper nutritional intake of parents include
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have a higher BMI compared to AA allele carriers. However, this difference is not found in low fat consuming group (<35% of energy intake).
186:
There appear to be some SNPs that make it more likely that a person will gain weight from a high fat diet; for people with AA genotype in the
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57:
The term "nutritional genomics" is an umbrella term including several subcategories, such as nutrigenetics, nutrigenomics, and
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705:
425:
426:"PHBI – Pharmagreen Starts Sales of MaxGenomicTM Supplement on Amazon.com and Develops Its Next Pre-Workout Formulation"
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331:"Nutrigenetics and Nutrigenomics: Viewpoints on the Current Status and Applications in Nutrition Research and Practice"
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and health. People in the field work toward developing an understanding of how the whole body responds to a food via
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showed a higher BMI compared those with TT genotype when having high fat or low carbohydrate dietary intake. The
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89:(SNPs) or other localized patterns, variation within a population may yield many more polymorphisms.
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The applications of nutritional genomics are multiple. With personalized assessment some disorders (
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or foods will raise or lower risks of diseases and damage to the human body.
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Matrix-assisted laser desorption ionization-time of flight mass spectrometer
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Bisen, Prakash A.; Debnath, Mousumi; Prasad, Godavarthi B.K.S. (2010).
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457:"Position of the Academy of Nutrition and Dietetics: Nutritional Genomics"
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Health, National
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85:. Yet, although certain disorders may be linked to certain
700:. Pinna, Kathryn,, Whitney, Ellie (Ninth ed.). Australia.
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528:
750:"Obesity: interactions of genome and nutrients intake"
388:"The new frontier of nutrition science: Nutrigenomics"
668:. National Center for Biotechnology Information (US).
606:. Springer Science & Business Media. p. 26.
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Camp, Kathryn M.; Trujillo, Elaine (February 2014).
506:"Efficient use of phosphorus in production animals"
64:
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461:Journal of the Academy of Nutrition and Dietetics
37:, is a science studying the relationship between
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604:Molecular Dianostics: Promises and Possibilities
174:consumption of lipids across all populations.
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392:Journal of the American Dietetic Association
27:Science of the Effects of Nutrition on Genes
1097:Matrix-assisted laser desorption ionization
624:clinical nutrition, 75(8), 1176–1192.
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728:: CS1 maint: location missing publisher (
626:https://doi.org/10.1038/s41430-020-00841-x
335:Journal of Nutrigenetics and Nutrigenomics
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510:nutriNews, la revista de nutriciĂłn animal
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529:nutraingredients-asia.com (2023-08-15).
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285:Journal of Food Science and Technology
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754:Preventive Nutrition and Food Science
748:Doo, Miae; Kim, Yangha (2015-03-01).
696:DeBruyne, Linda K. (8 January 2015).
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647:Cameron, Louise (9 November 2016).
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665:Nutritional and Metabolic Diseases
281:"Nutrigenomics research: a review"
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685:. National Academies Press (US).
279:Neeha, V. S.; Kinth, P. (2013).
65:Background and Preventive Health
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556:"The genetics of human obesity"
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229:Global Health Share Initiative
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1145:National Institutes of Health
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1061:Structure-based drug design
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554:Xia, Q; Grant, SF (2013).
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535:nutraingredients-asia.com
297:10.1007/s13197-012-0775-z
135:neurodegenerative disease
1107:Microfluidic-based tools
952:Human Connectome Project
884:Human Microbiome Project
1092:Electrospray ionization
964:Human Epigenome Project
766:10.3746/pnf.2015.20.1.1
386:Peregrin, Tony (2001).
244:Orthomolecular medicine
133:and the development of
59:nutritional epigenetics
1133:DNA Data Bank of Japan
1049:Human proteome project
852:Computational genomics
682:Genetics and Nutrition
249:Public health genomics
165:Coronary heart disease
151:coronary heart disease
1112:Isotope affinity tags
1066:Expression proteomics
504:Alvaro (2022-12-15).
79:Prader–Willi syndrome
872:Human Genome Project
857:Comparative genomics
31:Nutritional genomics
1205:Nutritional science
1082:2-D electrophoresis
1056:Call-map proteomics
914:Structural genomics
901:Population genomics
862:Functional genomics
183:or reduce obesity.
1036:Structural biology
847:Cognitive genomics
572:10.1111/nyas.12020
99:Mediterranean diet
93:Mediterranean diet
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1087:Mass spectrometer
896:Personal genomics
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254:Roger J. Williams
157:, alcoholism and
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538:. Retrieved
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432:. 2023-09-05
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39:human genome
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959:Epigenomics
891:Pangenomics
126:polyphenols
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1199:Categories
1044:Proteomics
981:Lipidomics
976:Immunomics
760:(1): 1–7.
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540:2024-02-16
515:2024-02-16
436:2024-02-16
261:References
239:Nutriomics
1220:Nutrition
971:Glycomics
774:2287-1098
724:cite book
716:910704712
483:2212-2672
355:1661-6758
219:Foodomics
122:quercetin
118:capsaicin
1215:Genomics
1183:Category
909:genomics
833:Genomics
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590:23360386
491:24439821
412:11716306
373:21625170
315:24425937
224:Genomics
207:See also
188:FTO gene
147:diabetes
114:lycopene
932:Biochip
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178:Obesity
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730:link
712:OCLC
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