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Nitroglycerin

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2339:. Some forms of nitroglycerin last much longer in the body than others. Nitroglycerin as well as the onset and duration of action of each form is different. The sublingual or tablet spray of nitroglycerin has a two minute onset and twenty five minute duration of action. The oral formulation of nitroglycerin has a thirty five minute onset and a duration of action of 4–8 hours. The transdermal patch has an onset of thirty minutes and a duration of action of ten to twelve hours. Continuous exposure to nitrates has been shown to cause the body to stop responding normally to this medicine. Experts recommend that the patches be removed at night, allowing the body a few hours to restore its responsiveness to nitrates. Shorter-acting preparations of nitroglycerin can be used several times a day with less risk of developing tolerance. Nitroglycerin was first used by 54: 459: 288: 2308:(volume of blood in the heart after filling); this is thought to be its primary mechanism of action. By decreasing preload, the heart has less blood to pump, which decreases oxygen requirement since the heart does not have to work as hard. Additionally, having a smaller preload reduces the ventricular transmural pressure (pressure exerted on the walls of the heart), which decreases the compression of heart arteries to allow more blood to flow through the heart. At higher doses, it also dilates arteries, thereby reducing 1007: 1903: 1550:. The explosion led to the loss of six lives, many injuries and much damage to the village. Little trace was found of the two horses. The UK Government was so alarmed at the damage caused and what could have happened in a city location (these two tons were part of a larger load coming from Germany via Liverpool) that they soon passed the Nitro-Glycerine Act of 1869. Liquid nitroglycerin was widely banned elsewhere, as well, and these legal restrictions led to Alfred Nobel and his company's developing 63: 1012: 997: 45: 1002: 1139: 1135: 1806: 2056:, has an emergency trap door at its base, which hangs over a large pool of very cold water and into which the whole reaction mixture (called the charge) can be dumped to prevent an explosion, a process referred to as drowning. If the temperature of the charge exceeds about 30 °C (86 °F) (actual value varying by country) or brown fumes are seen in the nitrator's vent, then it is immediately drowned. 1471: 2284: 1217: 1140: 1666:, with physical shock causing it to explode. If it has not been adequately purified during manufacture it can degrade over time to even more unstable forms. This makes nitroglycerin highly dangerous to transport or use. In its undiluted form, it is one of the world's most powerful explosives, comparable to the more recently developed 2221:
Smokeless powders were originally developed using nitrocellulose as the sole explosive ingredient. Therefore, they were known as single-base propellants. A range of smokeless powders that contains both nitrocellulose and nitroglycerin, known as double-base propellants, were also developed. Smokeless
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or a rifle ball when in that condition but on the other hand it appears to be more liable to explode on breaking, crushing, tamping, etc." Frozen nitroglycerine is much less energetic than liquid, and so must be thawed before use. Thawing it out can be extremely sensitizing, especially if impurities
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For workers in nitroglycerin (NTG) manufacturing facilities, the effects of withdrawal sometimes include "Sunday heart attacks" in those experiencing regular nitroglycerin exposure in the workplace, leading to the development of tolerance for the venodilating effects. Over the weekend, the workers
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in 1879. A few months before his death in 1896, Alfred Nobel was prescribed nitroglycerin for this heart condition, writing to a friend: "Isn't it the irony of fate that I have been prescribed nitro-glycerin, to be taken internally! They call it Trinitrin, so as not to scare the chemist and the
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Due to its high boiling point and subsequent low vapor pressure (0.00026 mmHg at 20 °C), pure nitroglycerin has practically no odor at room temperature, with a sweet and burning taste when ingested. Unintentional detonation may ensue when dropped, shaken, lit on fire, rapidly heated, exposed to
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caused by inadequate flow of blood and oxygen to the heart and as a potent antihypertensive agent. Nitroglycerin corrects the imbalance between the flow of oxygen and blood to the heart and the heart's energy demand. There are many formulations on the market at different doses. At low doses,
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temperature of 270 °C instead. With a melting point of 12.8 °C, the chemical is almost always encountered as a thick and viscous fluid, changing to a crystalline solid when frozen. Although the pure compound itself is colorless, in practice the presence of
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to and dependence on nitroglycerin after long-term exposure. Although rare, withdrawal can be fatal;symptoms include chest pain and other heart problems. These symptoms may be relieved with re-exposure to nitroglycerin or other suitable organic nitrates.
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formations. The technique involves displacing and detonating nitroglycerin in natural or hydraulically induced fracture systems, or displacing and detonating nitroglycerin in hydraulically induced fractures followed by wellbore shots using pelletized
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powders were originally supplied only for military use, but they were also soon developed for civilian use and were quickly adopted for sports. Some are known as sporting powders. Triple-base propellants contain nitrocellulose, nitroglycerin, and
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explosive, which is to say, it has excellent shattering ability. The heat liberated during detonation raises the temperature of the gaseous byproducts to about 5,000 °C (9,000 °F). With a standard enthalpy of explosive decomposition of
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to exploding is responsible for numerous devastating industrial accidents throughout its history. The chemical's characteristic reactivity may be reduced through the addition of desensitizing agents, which makes it less likely to explode. Clay
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resulted in an explosion on the Town Moor that killed eight people. In June 1869, two one-ton wagons loaded with nitroglycerin, then known locally as Powder-Oil, exploded in the road at the North Wales village of
4246: 1156: 4412: 2202:. He patented it in 1887. Ballistite was adopted by a number of European governments, as a military propellant. Italy was the first to adopt it. The British government and the Commonwealth governments adopted 1681:" by freezing it at a temperature below 45 to 55 °F (7 to 13 °C) depending on its purity. Its sensitivity to shock while frozen is somewhat unpredictable: "It is more insensitive to the shock from a 4599: 3925: 1020: 2186:
Nitroglycerin has an advantage over some other high explosives that on detonation it produces practically no visible smoke. Therefore, it is useful as an ingredient in the formulation of various kinds of
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and killing 15 people. This led to a complete ban on the transportation of liquid nitroglycerin in California. The on-site manufacture of nitroglycerin was thus required for the remaining hard-rock
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mixture is added slowly to the reaction vessel containing the mixed acid (not acid to glycerin). The nitrator is cooled with cold water or some other coolant mixture and maintained throughout the
1569:" (1875), were formed by mixing nitroglycerin with other inert absorbents, and many combinations were tried by other companies in attempts to get around Nobel's tightly held patents for dynamite. 977: 2024:(i.e., heat is produced), as usual for mixed-acid nitrations. If the mixture becomes too hot, it results in a runaway reaction, a state of accelerated nitration accompanied by the destructive 4683: 4551: 1591:. He began treating his patients with small diluted doses of nitroglycerin in 1878, and this treatment was soon adopted into widespread use after Murrell published his results in the journal 1709:. The nitroglycerin may have to be extracted from the desensitizer chemical to restore its effectiveness before use, for example by adding water to draw off ethanol used as a desensitizer. 4251: 173: 2503: 4221: 2044:
addition at about 22 °C (72 °F), hot enough for esterification to occur at a fast rate but cold enough to avoid runaway reaction. The nitrator vessel, often constructed of
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called "Blasting Oil", but this was extremely unstable and difficult to handle, as evidenced in numerous catastrophes. The buildings of the Krümmel factory were destroyed twice.
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it in 1867. It was supplied ready for use in the form of sticks, individually wrapped in greased waterproof paper. Dynamite and similar explosives were widely adopted for
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per gram, or 6.23 kJ/g, making nitroglycerin 49% more energetic on a mass basis than the standard definitional value assigned to TNT (precisely 1 kcal/g).
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Kaplan, K. J.; Taber, M.; Teagarden, J. R.; Parker, M.; Davison, R. (1985). "Association of methemoglobinemia and intravenous nitroglycerin administration".
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for the heat of formation of condensed phase nitroglycerin gives 1414 kJ/mol released if forming water vapor, and 1524 if forming liquid water.
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On Christmas Day 1867, an attempt to dispose of nine canisters of Blasting Oil that had been illegally stored at the White Swan Inn in the centre of
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Chen, Z.; Foster, M. W.; Zhang, J.; Mao, L.; Rockman, H. A.; Kawamoto, T.; Kitagawa, K.; Nakayama, K. I.; Hess, D. T.; Stamler, J. S. (2005).
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People can be exposed to nitroglycerin in the workplace by breathing it in, skin absorption, swallowing it, or eye contact. The
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known as "NG head" or "bang head". These headaches can be severe enough to incapacitate some people; however, humans develop a
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or another polynitrate may be added to lower the melting point and thereby avoid the necessity of thawing frozen explosive.
1078: 2754:." (Those drops constitute the new substance whose properties I will now describe, and which I will call "pyroglycerine".) 1842: 4561: 2714:[On several detonating compounds produced with nitric acid and sugar, dextrin, lactose, mannitol, and glycerin]. 2086:
Nitroglycerin is an oily liquid that explodes when subjected to heat, shock, or flame. The main use of nitroglycerin, by
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of the United Kingdom in 1889. The original Cordite Mk I consisted of 58% nitroglycerin, 37% guncotton, and 5.0%
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Chemically "desensitizing" nitroglycerin is possible to a point where it can be considered about as "safe" as modern
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per week. This amount required at least 336 tonnes of nitroglycerin per week (assuming no losses in production). The
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and a molecular weight of 227.0865 g/mol, nitroglycerin has a specific explosive energy density of 1.488 
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Marsh, N.; Marsh, A. (2000). "A short history of nitroglycerine and nitric oxide in pharmacology and physiology".
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in German) found in the Krümmel hills. Similar mixtures, such as "dualine" (1867), "lithofracteur" (1869), and "
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and water is produced. This is different from an electrophilic aromatic substitution reaction in which
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As is the case for many other explosives, nitroglycerin becomes more and more prone to exploding (i.e.
1186: 28: 3030: 3004: 1461:, and several factory workers were killed in an explosion at the Nobels' armaments factory in 1864 in 1439: 225: 3971: 3859: 2410: 1933:—a quite expensive pure nitric acid in which the oxides of nitrogen have been removed, as opposed to 1775:
The detonation velocity of nitroglycerin is 7820 meters per second, which is about 113% the speed of
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of 0.1 mg/m skin exposure over an 8-hour workday. At levels of 75 mg/m, nitroglycerin is
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Nitroglycerin in three different forms: intravenous, sublingual spray, and the nitroglycerin patch.
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Nitroglycerin belongs to a group of drugs called nitrates, which includes many other nitrates like
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public." The medical establishment also used the name "glyceryl trinitrate" for the same reason.
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developed the use of nitroglycerin as a blasting explosive by mixing nitroglycerin with inert
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sunlight and ozone, subjected to sparks and electrical discharges, or roughly handled. Its
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Di Carlo, F. J. (1975). "Nitroglycerin Revisited: Chemistry, Biochemistry, Interactions".
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The heat released can be calculated from the heats of formation. Using −371 kJ/
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experimented with the use of nitroglycerin to alleviate angina pectoris and to reduce the
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impurities left over during production tends to give it a slight yellowish tint.
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Nitroglycerin was the first practical explosive produced that was stronger than
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to treat angina attacks in 1878, with the discovery published that same year.
1945:. More often, this mixture is attained by the cheaper method of mixing fuming 1902: 1576:, which increases the viscosity of the mix, are commonly known as "gelatins". 1090: 5105: 4983: 4732: 4541: 4170: 4150: 4145: 4130: 3191: 3164: 2356: 2006: 1973: 1954: 1946: 1942: 1922: 1631: 1527: 1347: 1102: 637: 606: 596: 276: 3758:
Detailed and horrific stories of the historical use of nitroglycerin-filled
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cGMP preferring PDE inhibitors (e.g., sildenafil, paraxanthine, tadalafil)
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Colorless or pale yellow, oily liquid or tetraclinic/orthorhombic crystal
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lose the tolerance, and when they are re-exposed on Monday, the drastic
2218:. Ballistite and cordite were both manufactured in the form of "cords". 1148: 1110: 265: 5046: 5026: 4960: 4614: 4031: 4026: 3915: 3895: 3712:"Nitroglycerine! Terrible Explosion and Loss of Lives in San Francisco" 2336: 2195: 2152: 2069: 1977: 1962: 1635: 1593: 1507: 1492: 1462: 1340: 1324: 1155: 899: 628: 565: 326: 296: 236: 3151:"Zusammensetzung der Zuckerasche" [Composition of sugar ash]. 2372:, dizziness, and a headache. This is referred to as "Monday disease." 1717:
When nitroglycerin explodes, the products after cooling are given by:
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Infrequent exposure to high doses of nitroglycerin can cause severe
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Except where otherwise noted, data are given for materials in their
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nitroglycerin dilates veins more than arteries, thereby reducing
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in Germany and built an isolated factory in the Krümmel hills of
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under conditions appropriate to the formation of the nitric acid
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Assembly of Life Sciences (U.S.) Advisory Center on Toxicology.
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Nitroglycerin was adopted as a commercially useful explosive by
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InChI=1S/C3H5N3O9/c7-4(8)13-1-3(15-6(11)12)2-14-5(9)10/h3H,1-2H2
5069: 4965: 4859: 4422: 3401:"nitroglycerin, Nitro-Bid: Drug Facts, Side Effects and Dosing" 2144: 2140: 1991: 1643: 1506:
In April 1866, several crates of nitroglycerin were shipped to
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InChI=1/C3H5N3O9/c7-4(8)13-1-3(15-6(11)12)2-14-5(9)10/h3H,1-2H2
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Nitroglycerin is available in tablets, ointment, solution for
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Early in its history, liquid nitroglycerin was found to be "
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Nitroglycerin can be produced by acid-catalyzed nitration of
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Large quantities of nitroglycerin were manufactured during
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have used dynamite for construction and demolition work.
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Clinical Environmental Health and Toxic Exposures: Latex
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On p. 197, Sobrero names nitroglycerin "pyroglycerine":
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and warned vigorously against its use as an explosive.
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Nitroxyl anion (NO; oxonitrate(1-), hyponitrite anion)
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North Wales Daily Post newspaper of October 14th 2018.
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Clinical and Experimental Pharmacology and Physiology
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Memorie della Reale Accademia delle Scienze di Torino
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National Institute for Occupational Safety and Health
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National Institute for Occupational Safety and Health
2280:), and nitric oxide is a potent natural vasodilator. 1522:. One of the remaining crates exploded, destroying a 1064: 3716:
Central Pacific Railroad Photographic History Museum
3508:"William Murrell, physician and practical therapist" 1554:
in 1867. This was made by mixing nitroglycerin with
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Methylamine hexamethylene methylamine/NO (MAHMA/NO)
2246:. This was an early, low-cost, flexible explosive. 1830:. Unsourced material may be challenged and removed. 1391:(causing dilation of the vascular system) to treat 335: 3586:. Lippincott Williams & Wilkins. p. 264. 3283:(3rd ed.). USA: Academic Press. p. 569. 3112:"Tales of Destruction...Is Nitroglycerin In This?" 2624: 2504:"Hazard Rating Information for NFPA Fire Diamonds" 1917:The industrial manufacturing process often reacts 1657: 4136:Amyl nitrite (isoamyl nitrite, isopentyl nitrite) 3481:"Nitroglycerin for angina, February 1997, Vol. 7" 3038:Proceedings of the Lake Superior Mining Institute 3012:Proceedings of the Lake Superior Mining Institute 873:Intravenous, by mouth, under the tongue, topical 5103: 3580:Sullivan, John B. Jr.; Krieger, Gary R. (2001). 2162:Nitroglycerin has been used in conjunction with 1052: 394: 3997:Naproxcinod (nitronaproxen; AZD-3582, HCT-3012) 3579: 2881:"Nitroglycerin as a remedy for angina pectoris" 2631:Proceedings of the National Academy of Sciences 1383:Nitroglycerin has been used for over 130 years 1137: 611:218 °C (424 °F; 491 K) Explodes 148: 3573: 3334: 1280:, is a dense, colorless or pale yellow, oily, 1060: 4413:N-Acetyl-N-acetoxy-4-chlorobenzenesulfonamide 3972:Ethylene glycol dinitrate (EGDN; nitroglycol) 3793: 3607: 2918: 2916: 2377:Occupational Safety and Health Administration 3751:CDC - NIOSH Pocket Guide to Chemical Hazards 3663:. National Academies. p. 115. NAP:11288 3344:Shale Oil, Tar Sand and Related Fuel Sources 3264:: CS1 maint: multiple names: authors list ( 3105: 3103: 3057:"Tales of Destruction...Thawing Can Be Hell" 2036:gas at high risk of an explosion. Thus, the 1343:in artillery and firearms since the 1880s. 27:For the use of this chemical as a drug, see 2581:(97th ed.). CRC Press. pp. 3–540. 1601: 1583:helped alleviate chest pain, the physician 3800: 3786: 3650: 3613: 3554: 3306:"Alfred Nobel and the History of Dynamite" 2913: 2891:(2890): 80–81, 113–115, 151–152, 225–227. 2453: 2451: 1921:with a nearly 1:1 mixture of concentrated 1662:In its undiluted form, nitroglycerin is a 1376:) is an example of such an agent, forming 601:12.8 °C (55.0 °F; 285.9 K) 457: 286: 244: 4156:Isobutyl nitrite (2-methylpropyl nitrite) 4066:Nitroglycerin (glyceryl trinitrate (GTN)) 3531: 3505: 3100: 2904: 2660: 2650: 2206:instead, which had been developed by Sir 1890:Learn how and when to remove this message 1686:are present or the warming is too rapid. 1446:. Sobrero initially called his discovery 1415:) in 2002. Nitroglycerin is available in 414: 3328: 3204: 3048: 2971: 2796:Ramsay, Sir William (28 December 1907). 2484:NIOSH Pocket Guide to Chemical Hazards. 2393:immediately dangerous to life and health 2282: 1901: 1640:Royal Navy Cordite Factory, Holton Heath 1622:, the largest propellant factory in the 1469: 4232:S-Nitrosocysteine (SNC, CysNO, SNO-Cys) 4222:S-Nitroso-N-valerylpenicillamine (SNVP) 3335:Miller, J. S.; Johansen, R. T. (1976). 3240:Lewis, Richard J., Sr (15 March 2007). 3124: 3072: 3070: 2922: 2878: 2732: 2709: 2448: 2102:have largely replaced it in munitions. 1614:for use as military propellants and in 1510:, three of which were destined for the 453: 372: 264: 14: 5104: 4217:S-Nitroso-N-acetylpenicillamine (SNAP) 4091:Sodium trioxodinitrate (Angeli's salt) 3687:NIOSH Pocket Guide to Chemical Hazards 3278: 3242:Hawley's Condensed Chemical Dictionary 3125:Informatics, NIST Office of Data and. 3028: 3002: 2346: 2147:, for clearing farmland of stumps, in 277: 3781: 3239: 3029:Hurter, Charles S. (22 August 1911). 3022: 3003:Hurter, Charles S. (22 August 1911). 2996: 2593:"Nitroglycerin, desensitized, liquid" 2579:CRC Handbook of Chemistry and Physics 1965:nitric acid (consisting of about 70% 485:Key: SNIOPGDIGTZGOP-UHFFFAOYSA-N 224: 204: 5052:non-selective PDE inhibitors (e.g., 3836:Nitric oxide (NO; nitrogen monoxide) 3555:Amdur, Mary O.; Doull, John (1991). 3067: 2798:"The Manufacture of High Explosives" 2546: 2544: 2542: 2060:Use as an explosive and a propellant 1828:adding citations to reliable sources 1799: 1431:. It was synthesized by the Italian 1319:, and as such it is employed in the 854: 844: 4076:Pentaerithrityl tetranitrate (PETN) 3962:Diethylene glycol dinitrate (DEGDN) 3548: 3109: 3054: 2979:"Is Nitroglycerine In This? Page 5" 2685:"Unknown, behind paywall, archived" 2603:from the original on 26 August 2023 1534:required for the completion of the 495:Key: SNIOPGDIGTZGOP-UHFFFAOYAR 385: 355: 24: 4981:Indirect/downstream NO modulators: 4749:Asymmetric dimethylarginine (ADMA) 3858: 3303: 2576: 2230:. Blasting gelatin, also known as 1419:, sprays, ointments, and patches. 1299:. Chemically, the substance is an 1133: 25: 5158: 5112:Aldehyde dehydrogenase inhibitors 4779:Nitroarginine methyl ester (NAME) 4242:S-Nitrosoglutathione (GSNO, SNOG) 4212:S-Nitroso-N-acetylcysteine (SNAC) 4086:Propylene glycol dinitrate (PGDN) 3841:Nitrosonium (NO; nitrosyl cation) 3704: 3398: 2539: 2198:, by combining nitroglycerin and 1929:. This can be produced by mixing 1284:liquid most commonly produced by 935: 683:Trigonal planar at N7, N8, and N9 3756:The Tallini Tales of Destruction 3628:10.1046/j.1440-1681.2000.03240.x 3180:Annalen der Chemie und Pharmacie 3153:Annalen der Chemie und Pharmacie 2028:of organic materials by the hot 2001:is thus added as an ester C−O−NO 1804: 1795: 1331:industries. It is combined with 1215: 1010: 1005: 1000: 995: 549: 543: 61: 52: 43: 4307:Diethylenetriamine/NO (DETA/NO) 3675: 3557:Casarett and Doull's Toxicology 3506:Smith, E.; Hart, F. D. (1971). 3499: 3473: 3448: 3411: 3373: 3297: 3279:Wexler, Philip (7 April 2014). 3272: 3233: 3198: 3171: 3144: 3118: 2941: 2872: 2863: 2839: 2816: 2759: 2726: 2703: 1983:species, which are attacked by 1815:needs additional citations for 1658:Instability and desensitization 1536:First transcontinental railroad 1211:(at 25 °C , 100 kPa). 4507:N-(1-Iminoethyl)-L-ornithine ( 3421:American Journal of Cardiology 2677: 2585: 2570: 2514: 2496: 2477: 2316:, increase of heart rate, and 2249: 1969:, with the rest being water). 1487:One year later, Nobel founded 959:Occupational safety and health 555: 537: 80:Propane-1,2,3-triyl trinitrate 13: 1: 5090:Receptor/signaling modulators 4759:Guanidinoethyldisulfide (GED) 3977:Isosorbide mononitrate (ISMN) 3967:Erythritol tetranitrate (ETN) 2897:10.1016/s0140-6736(02)46032-1 2554:. 16 May 2013. Archived from 2442: 2272:in the body by mitochondrial 2032:and the release of poisonous 1712: 1697:, such as by the addition of 1579:Following the discovery that 1572:Dynamite mixtures containing 1204: 1180:(US health exposure limits): 701:Tetrahedral at C1, C2, and C3 431:0143, 0144, 1204, 3064, 3319 4227:S-Nitrosocaptopril (SNO-Cap) 4056:Nitroflurbiprofen (HCT-1026) 4051:Nitroatorvastatin (NCX-6560) 3771:The Periodic Table of Videos 3434:10.1016/0002-9149(85)90324-8 2256:Medical use of nitroglycerin 2194:Alfred Nobel then developed 2166:, a process used to recover 680:Tetragonal at C1, C2, and C3 7: 4702:Aminoguanidine (pimagedine) 4595:Aminoguanidine (pimagedine) 4492:Aminoguanidine (pimagedine) 4256:N-Nitroso compounds (e.g., 4071:Nitropravastatin (NCX-6550) 3982:Isosorbide dinitrate (ISDN) 3762:to restart petroleum wells. 2398: 2132:tasks, such as in drilling 2052:and generally stirred with 1648:Canadian Explosives Limited 1638:had its own factory at the 92:1,2,3-Tris(nitrooxy)propane 10: 5163: 4988:AT-II receptor antagonists 4733:Nitroarginine (NNA, NOARG) 4570:1-Amino-2-hydroxyguanidine 4542:Nitroarginine (NNA, NOARG) 4289:Sodium nitroprusside (SNP) 3774:(University of Nottingham) 3559:(4th ed.). Elsevier. 3281:Encyclopedia of Toxicology 2389:recommended exposure limit 2381:permissible exposure limit 2253: 2120:. He named this explosive 2063: 1618:work. During World War I, 1422: 704:Dihedral at N7, N8, and N9 29:Nitroglycerin (medication) 26: 5083: 4900: 4873: 4811: 4741: 4692: 4560: 4447: 4438: 4421: 3938: 3849: 3821: 3219:10.3109/03602537508993747 2925:Drug Discovery: A History 2879:Murrell, William (1879). 2733:Sobrero, Ascanio (1849). 2710:Sobrero, Ascagne (1847). 2411:Ethylene glycol dinitrate 2379:has set the legal limit ( 2335:, or sprays administered 1688:Ethylene glycol dinitrate 1348:spontaneous decomposition 1205: 1174: 976: 956: 951: 877: 827: 760: 711: 664: 524: 504: 469: 132: 86: 74: 69: 60: 51: 42: 5137:Sugar alcohol explosives 4467:3-Chloro-5-nitroindazole 4302:Diethylamine/NO (DEA/NO) 4274:Metal nitrosyl complexes 4202:S-Nitrosoalbumin (SNALB) 3896:Cinaciguat (BAY 58-2667) 3727:– 1866 Newspaper article 3192:10.1002/jlac.18540920309 3165:10.1002/jlac.18480640364 3082:Encyclopaedia Britannica 2923:Sneader, Walter (2005). 1931:white fuming nitric acid 1602:Wartime production rates 1512:Central Pacific Railroad 1489:Alfred Nobel and Company 1293:white fuming nitric acid 1073:Precautionary statements 5059:PDE9 inhibitors (e.g., 4547:Pentamidine isethionate 4457:3-Bromo-7-nitroindazole 4344:Heterocyclic compounds: 3868:Activators/stimulators: 3512:British Medical Journal 3456:"IntraMed – Bienvenido" 3207:Drug Metabolism Reviews 3178:"Ueber Nitroglycerin". 3114:. Analog Services, Inc. 3063:. Analog Services, Inc. 2927:. John Wiley and Sons. 2652:10.1073/pnas.0503723102 2406:Erythritol tetranitrate 2318:orthostatic hypotension 2299:, a painful symptom of 1906:Nitroglycerin synthesis 1520:Sierra Nevada Mountains 1440:Théophile-Jules Pelouze 1438:in 1846, working under 1303:compound rather than a 1278:1,2,3-trinitroxypropane 95:1,2,3-Trinitroxypropane 5016:L-Type calcium channel 3524:10.1136/bmj.3.5775.632 2597:CAMEO Chemicals | NOAA 2301:ischemic heart disease 2288: 2274:aldehyde dehydrogenase 2266:isosorbide mononitrate 1935:red fuming nitric acid 1907: 1482: 1409:aldehyde dehydrogenase 1144: 516:C(C(CO(=O))O(=O))O(=O) 5117:Disulfiram-like drugs 4620:Cindunistat (SD-6010) 4575:2-Ethylaminoguanidine 4332:Spermine/NO (SPER/NO) 4129:O-Nitroso compounds ( 3660:Toxicological Reports 2286: 1905: 1626:, produced about 800 1532:drilling and blasting 1473: 1401:chronic heart failure 1335:to form double-based 1143: 672:Coordination geometry 5006:receptor antagonists 4679:Ronopterin (VAS-203) 4378:Molsidomine (SIN-10) 4299:(diazeniumdiolates): 4279:Roussin's black salt 3992:Mannitol hexanitrate 3186:(3): 305–306. 1854. 3159:(3): 398–399. 1848. 3088:on 12 September 2002 2510:on 17 February 2015. 2431:Xylitol pentanitrate 2426:Tetranitratoxycarbon 2416:Mannitol hexanitrate 2262:isosorbide dinitrate 2164:hydraulic fracturing 1824:improve this article 1784:−1414 kJ/ 1616:military engineering 1395:conditions, such as 1352:atmospheric pressure 1126:(fire diamond) 912:Biological half-life 728:Friction sensitivity 76:Preferred IUPAC name 5127:Explosive chemicals 4373:Linsidomine (SIN-1) 4270:Nitrosyl compounds: 4237:S-Nitrosodiclofenac 4207:S-Nitrosated AR545C 4192:S-Nitroso compounds 3352:1976sots.rept...98M 2953:beyonddiscovery.org 2852:American Experience 2802:Scientific American 2643:2005PNAS..10212159C 2637:(34): 12159–12164. 2347:Industrial exposure 2333:transdermal patches 2022:exothermic reaction 1650:cordite factory at 1543:Newcastle upon Tyne 1444:University of Turin 1270:glyceryl trinitrate 738:Detonation velocity 618:Solubility in water 573: g·mol 186:Beilstein Reference 98:Glyceryl trinitrate 39: 5142:Italian inventions 4284:Roussin's red salt 4141:Cyclohexyl nitrite 4032:Nipradilol (K-351) 3731:WebBook page for C 2959:on 1 November 2010 2777:on 15 January 2009 2289: 2157:military engineers 2118:diatomaceous earth 1957:containing excess 1941:—and concentrated 1908: 1620:HM Factory, Gretna 1556:diatomaceous earth 1538:in North America. 1526:company office in 1483: 1479:patent application 1417:sublingual tablets 1374:diatomaceous earth 1238:Infobox references 1145: 37: 5132:Liquid explosives 5097: 5096: 4922: 4913: 4896: 4895: 4829: 4807: 4806: 4727: 4723: 4714: 4710: 4707:N-(1-Iminoethyl)- 4673: 4669: 4660: 4656: 4653:N-(1-Iminoethyl)- 4647: 4643: 4640:N-(1-Iminoethyl)- 4580:2-Iminopiperidine 4536: 4532: 4523: 4519: 4510: 4432: 4161:Isopropyl nitrite 4107:Nitroso compounds 3949: 3934: 3933: 3593:978-0-683-08027-8 3518:(5775): 632–633. 3399:Ogbru, Omudhome. 3361:on 2 October 2018 3316:on 28 August 2021 3251:978-0-471-76865-4 3110:Tallini, Rick F. 3055:Tallini, Rick F. 2934:978-0-471-89980-8 2804:. Springer Nature 2522:"Ascanio Sobrero" 2322:methemoglobinemia 2244:potassium nitrate 2130:civil engineering 1937:, which contains 1925:and concentrated 1900: 1899: 1892: 1874: 1664:contact explosive 1246:Chemical compound 1244: 1243: 1035:Hazard statements 972:Explosive, toxic 944:(Pharmacist only) 939: 718:Shock sensitivity 438:CompTox Dashboard 174:Interactive image 124:-Trinitroglycerin 34:Chemical compound 16:(Redirected from 5154: 5023:dihydropyridines 4923:-arginine (NOHA) 4920: 4911: 4865:alpha aminoacids 4835:chlorogenic acid 4830:-arginine (NOHA) 4827: 4725: 4721: 4712: 4708: 4671: 4667: 4658: 4654: 4645: 4641: 4534: 4530: 4521: 4517: 4508: 4462:3-Chloroindazole 4445: 4444: 4436: 4435: 4426: 4124: 4123: 4061:Nitrofluvastatin 4045: 4044: 3987:Itramin tosilate 3943: 3856: 3855: 3802: 3795: 3788: 3779: 3778: 3766:Dynamite and TNT 3726: 3724: 3722: 3699: 3698: 3696: 3694: 3683:"Nitroglycerine" 3679: 3673: 3672: 3670: 3668: 3654: 3648: 3647: 3611: 3605: 3604: 3602: 3600: 3577: 3571: 3570: 3552: 3546: 3545: 3535: 3503: 3497: 3496: 3494: 3492: 3483:. Archived from 3477: 3471: 3470: 3468: 3466: 3460:www.intramed.net 3452: 3446: 3445: 3415: 3409: 3408: 3396: 3385: 3384: 3377: 3371: 3370: 3368: 3366: 3360: 3354:. Archived from 3341: 3332: 3326: 3325: 3323: 3321: 3312:. Archived from 3301: 3295: 3294: 3276: 3270: 3269: 3263: 3255: 3237: 3231: 3230: 3202: 3196: 3195: 3175: 3169: 3168: 3148: 3142: 3141: 3139: 3137: 3131:webbook.nist.gov 3122: 3116: 3115: 3107: 3098: 3097: 3095: 3093: 3084:. Archived from 3074: 3065: 3064: 3052: 3046: 3045: 3035: 3026: 3020: 3019: 3009: 3000: 2994: 2993: 2991: 2989: 2975: 2969: 2968: 2966: 2964: 2955:. Archived from 2949:"History of TNG" 2945: 2939: 2938: 2920: 2911: 2910: 2908: 2876: 2870: 2867: 2861: 2860: 2843: 2837: 2835: 2834:on 10 July 2006. 2830:. Archived from 2820: 2814: 2813: 2811: 2809: 2793: 2787: 2786: 2784: 2782: 2773:. Archived from 2763: 2757: 2746: 2730: 2724: 2723: 2707: 2701: 2700: 2698: 2696: 2687:. Archived from 2681: 2675: 2674: 2664: 2654: 2622: 2613: 2612: 2610: 2608: 2589: 2583: 2582: 2574: 2568: 2567: 2565: 2563: 2548: 2537: 2536: 2534: 2532: 2526:Oxford Reference 2518: 2512: 2511: 2506:. Archived from 2500: 2494: 2493: 2481: 2475: 2474: 2472: 2470: 2461:. Archived from 2455: 2189:smokeless powder 2112:, particularly " 2078:smokeless powder 2034:nitrogen dioxide 2016:The addition of 1949:, also known as 1895: 1888: 1884: 1881: 1875: 1873: 1832: 1808: 1800: 1764: 1760: 1753: 1745: 1738: 1564: 1459:Emil Oskar Nobel 1337:smokeless powder 1258:trinitroglycerol 1228: 1222: 1219: 1218: 1200: 1196: 1165: 1158: 1151: 1136: 1116: 1112: 1108: 1104: 1100: 1096: 1092: 1088: 1084: 1080: 1066: 1062: 1058: 1054: 1050: 1046: 1042: 1014: 1009: 1004: 999: 937: 934: 920: 879:Pharmacokinetics 858: 848: 822: 815: 791: 784: 761:Thermochemistry 745: 572: 557: 551: 545: 539: 532:Chemical formula 462: 461: 446: 444: 418: 398: 387: 376: 359: 339: 315:Gmelin Reference 298: 290: 279: 268: 248: 228: 208: 176: 152: 110:Trinitroglycerin 65: 56: 47: 40: 36: 21: 5162: 5161: 5157: 5156: 5155: 5153: 5152: 5151: 5147:Glycerol esters 5102: 5101: 5098: 5093: 5079: 5043:PDE5 inhibitors 5005: 4969: 4956: 4892: 4869: 4803: 4737: 4688: 4556: 4482:7-Nitroindazole 4477:6-Nitroindazole 4472:5-Nitroindazole 4425: 4417: 4194:(thionitrites): 4122: 4119: 4118: 4117: 4081:Propatylnitrate 4043: 4040: 4039: 4038: 3942: 3930: 3845: 3817: 3806: 3746: 3742: 3738: 3734: 3720: 3718: 3710: 3707: 3702: 3692: 3690: 3681: 3680: 3676: 3666: 3664: 3655: 3651: 3612: 3608: 3598: 3596: 3594: 3578: 3574: 3567: 3553: 3549: 3504: 3500: 3490: 3488: 3479: 3478: 3474: 3464: 3462: 3454: 3453: 3449: 3416: 3412: 3397: 3388: 3381:"Nitroglycerin" 3379: 3378: 3374: 3364: 3362: 3358: 3339: 3333: 3329: 3319: 3317: 3310:About.com Money 3302: 3298: 3291: 3277: 3273: 3257: 3256: 3252: 3238: 3234: 3203: 3199: 3177: 3176: 3172: 3150: 3149: 3145: 3135: 3133: 3127:"Nitroglycerin" 3123: 3119: 3108: 3101: 3091: 3089: 3078:"Nitroglycerin" 3076: 3075: 3068: 3053: 3049: 3033: 3027: 3023: 3007: 3001: 2997: 2987: 2985: 2983:www.logwell.com 2977: 2976: 2972: 2962: 2960: 2947: 2946: 2942: 2935: 2921: 2914: 2877: 2873: 2868: 2864: 2845: 2844: 2840: 2822: 2821: 2817: 2807: 2805: 2794: 2790: 2780: 2778: 2765: 2764: 2760: 2731: 2727: 2708: 2704: 2694: 2692: 2683: 2682: 2678: 2623: 2616: 2606: 2604: 2591: 2590: 2586: 2575: 2571: 2561: 2559: 2550: 2549: 2540: 2530: 2528: 2520: 2519: 2515: 2502: 2501: 2497: 2482: 2478: 2468: 2466: 2457: 2456: 2449: 2445: 2440: 2401: 2370:fast heart rate 2349: 2341:William Murrell 2297:angina pectoris 2258: 2252: 2228:naval artillery 2216:petroleum jelly 2153:demolition work 2084: 2064:Main articles: 2062: 2004: 1959:sulfur trioxide 1939:nitrogen oxides 1896: 1885: 1879: 1876: 1839:"Nitroglycerin" 1833: 1831: 1821: 1809: 1798: 1762: 1759: 1755: 1751: 1747: 1744: 1740: 1737: 1733: 1729: 1725: 1721: 1715: 1695:high explosives 1660: 1604: 1585:William Murrell 1562: 1485: 1484: 1436:Ascanio Sobrero 1425: 1397:angina pectoris 1309:Ascanio Sobrero 1301:organic nitrate 1247: 1240: 1235: 1234: 1233:  ?) 1224: 1220: 1216: 1212: 1198: 1194: 1190: 1170: 1169: 1168: 1167: 1160: 1153: 1146: 1142: 1134: 1075: 1037: 1023: 992: 969: 947: 918: 914: 902: 890: 888:Bioavailability 870: 867: 837: 820: 816: 813: 807: 803: 800: 799:Std enthalpy of 789: 785: 782: 776: 772: 769: 768:Std enthalpy of 743: 712:Explosive data 707: 695: 693:Molecular shape 686: 674: 620: 570: 560: 554: 548: 542: 534: 520: 517: 512: 511: 500: 497: 496: 493: 487: 486: 483: 477: 476: 465: 447: 440: 421: 401: 388: 362: 342: 329: 317: 308: 271: 251: 231: 211: 188: 179: 166: 155: 142: 128: 127: 82: 81: 35: 32: 23: 22: 15: 12: 11: 5: 5160: 5150: 5149: 5144: 5139: 5134: 5129: 5124: 5122:Nitrate esters 5119: 5114: 5095: 5094: 5084: 5081: 5080: 5078: 5077: 5067: 5064: 5057: 5050: 5040: 5030: 5013: 5003: 4999: 4984:ACE inhibitors 4977: 4976: 4971: 4967: 4963: 4958: 4954: 4950: 4945: 4940: 4935: 4926: 4925: 4916: 4904: 4902: 4898: 4897: 4894: 4893: 4891: 4890: 4885: 4879: 4877: 4871: 4870: 4868: 4867: 4862: 4857: 4852: 4847: 4842: 4837: 4832: 4823: 4817: 4815: 4809: 4808: 4805: 4804: 4802: 4801: 4796: 4791: 4786: 4781: 4776: 4771: 4766: 4761: 4756: 4751: 4745: 4743: 4739: 4738: 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3878: 3873: 3864: 3862: 3853: 3847: 3846: 3844: 3843: 3838: 3833: 3827: 3825: 3819: 3818: 3805: 3804: 3797: 3790: 3782: 3776: 3775: 3763: 3753: 3748: 3744: 3740: 3736: 3732: 3728: 3706: 3705:External links 3703: 3701: 3700: 3674: 3649: 3622:(4): 313–319. 3606: 3592: 3572: 3566:978-0071052399 3565: 3547: 3498: 3487:on 10 May 2017 3472: 3447: 3428:(1): 181–183. 3410: 3386: 3372: 3327: 3304:Bellis, Mary. 3296: 3290:978-0123864543 3289: 3271: 3250: 3232: 3197: 3170: 3143: 3117: 3099: 3066: 3047: 3021: 2995: 2970: 2940: 2933: 2912: 2871: 2862: 2838: 2828:NobelPrize.org 2815: 2788: 2771:NobelPrize.org 2758: 2756: 2755: 2741:. 2nd Series. 2725: 2716:Comptes Rendus 2702: 2691:on 10 May 2017 2676: 2614: 2584: 2577:Haynes, W. M. 2569: 2558:on 16 May 2013 2538: 2513: 2495: 2476: 2465:on 16 May 2013 2446: 2444: 2441: 2439: 2438: 2433: 2428: 2423: 2421:Methyl nitrate 2418: 2413: 2408: 2402: 2400: 2397: 2348: 2345: 2314:blood pressure 2264:(Isordil) and 2254:Main article: 2251: 2248: 2224:nitroguanidine 2208:Frederick Abel 2061: 2058: 2054:compressed air 2020:results in an 2007:nitronium ions 2002: 1898: 1897: 1812: 1810: 1803: 1797: 1794: 1766: 1765: 1757: 1749: 1742: 1735: 1731: 1727: 1723: 1714: 1711: 1707:dinitrotoluene 1659: 1656: 1652:Nobel, Ontario 1624:United Kingdom 1603: 1600: 1589:blood pressure 1574:nitrocellulose 1468: 1467: 1424: 1421: 1333:nitrocellulose 1305:nitro compound 1245: 1242: 1241: 1236: 1214: 1213: 1209:standard state 1206: 1203: 1202: 1191: 1185: 1182: 1181: 1172: 1171: 1161: 1154: 1147: 1132: 1131: 1130: 1129: 1127: 1118: 1117: 1076: 1071: 1068: 1067: 1038: 1033: 1030: 1029: 1024: 1019: 1016: 1015: 993: 988: 985: 984: 974: 973: 970: 967: 964: 963: 954: 953: 949: 948: 946: 945: 931: 929: 923: 922: 915: 910: 907: 906: 903: 898: 895: 894: 891: 886: 883: 882: 875: 874: 871: 868:administration 864: 861: 860: 838: 833: 830: 829: 825: 824: 817: 811: 805: 797: 794: 793: 786: 780: 774: 766: 763: 762: 758: 757: 754: 748: 747: 740: 734: 733: 730: 724: 723: 720: 714: 713: 709: 708: 706: 705: 702: 698: 696: 691: 688: 687: 685: 684: 681: 677: 675: 670: 667: 666: 662: 661: 658: 649: 648: 631: 625: 624: 621: 616: 613: 612: 609: 603: 602: 599: 593: 592: 589: 583: 582: 579: 575: 574: 568: 562: 561: 558: 552: 546: 540: 535: 530: 527: 526: 522: 521: 519: 518: 515: 507: 506: 505: 502: 501: 499: 498: 494: 491: 490: 488: 484: 481: 480: 472: 471: 470: 467: 466: 464: 463: 450: 448: 436: 433: 432: 429: 423: 422: 420: 419: 411: 409: 403: 402: 400: 399: 391: 389: 381: 378: 377: 370: 364: 363: 361: 360: 352: 350: 344: 343: 341: 340: 332: 330: 325: 322: 321: 318: 313: 310: 309: 307: 306: 302: 300: 292: 291: 281: 273: 272: 270: 269: 261: 259: 253: 252: 250: 249: 241: 239: 233: 232: 230: 229: 221: 219: 213: 212: 210: 209: 201: 199: 193: 192: 189: 184: 181: 180: 178: 177: 169: 167: 160: 157: 156: 154: 153: 145: 143: 138: 135: 134: 130: 129: 126: 125: 111: 108: 105: 102: 99: 96: 93: 89: 88: 84: 83: 79: 78: 72: 71: 67: 66: 58: 57: 49: 48: 38:Nitroglycerin 33: 18:Nitroglycerine 9: 6: 4: 3: 2: 5159: 5148: 5145: 5143: 5140: 5138: 5135: 5133: 5130: 5128: 5125: 5123: 5120: 5118: 5115: 5113: 5110: 5109: 5107: 5100: 5092: 5091: 5088: 5082: 5075: 5071: 5068: 5065: 5062: 5058: 5055: 5051: 5048: 5044: 5041: 5038: 5034: 5031: 5028: 5024: 5020: 5017: 5014: 5011: 5007: 5000: 4997: 4993: 4989: 4985: 4982: 4979: 4978: 4975: 4972: 4970: 4964: 4962: 4959: 4957: 4951: 4949: 4946: 4944: 4941: 4939: 4936: 4934: 4931: 4928: 4927: 4924: 4917: 4915: 4909: 4906: 4905: 4903: 4899: 4889: 4886: 4884: 4883:Calmidazolium 4881: 4880: 4878: 4876: 4872: 4866: 4863: 4861: 4858: 4856: 4853: 4851: 4848: 4846: 4843: 4841: 4838: 4836: 4833: 4831: 4824: 4822: 4819: 4818: 4816: 4814: 4810: 4800: 4797: 4795: 4792: 4790: 4787: 4785: 4782: 4780: 4777: 4775: 4772: 4770: 4767: 4765: 4762: 4760: 4757: 4755: 4752: 4750: 4747: 4746: 4744: 4740: 4734: 4731: 4729: 4718: 4716: 4705: 4703: 4700: 4699: 4697: 4695: 4691: 4685: 4682: 4680: 4677: 4675: 4664: 4662: 4651: 4649: 4638: 4636: 4633: 4631: 4628: 4626: 4623: 4621: 4618: 4616: 4613: 4611: 4608: 4606: 4603: 4601: 4598: 4596: 4593: 4591: 4588: 4586: 4583: 4581: 4578: 4576: 4573: 4571: 4568: 4567: 4565: 4563: 4559: 4553: 4550: 4548: 4545: 4543: 4540: 4538: 4527: 4525: 4514: 4512: 4505: 4503: 4500: 4498: 4495: 4493: 4490: 4488: 4485: 4483: 4480: 4478: 4475: 4473: 4470: 4468: 4465: 4463: 4460: 4458: 4455: 4454: 4452: 4450: 4446: 4443: 4441: 4437: 4434: 4430: 4424: 4420: 4414: 4411: 4409: 4406: 4404: 4401: 4399: 4396: 4394: 4391: 4388: 4387: 4384: 4381: 4379: 4376: 4374: 4371: 4369: 4366: 4364: 4359: 4356: 4354: 4351: 4349: 4345: 4342: 4341: 4338: 4335: 4333: 4330: 4328: 4325: 4323: 4320: 4318: 4315: 4313: 4310: 4308: 4305: 4303: 4300: 4298: 4294: 4293: 4290: 4287: 4285: 4282: 4280: 4277: 4275: 4271: 4268: 4267: 4264: 4261: 4259: 4253: 4250: 4248: 4245: 4243: 4240: 4238: 4235: 4233: 4230: 4228: 4225: 4223: 4220: 4218: 4215: 4213: 4210: 4208: 4205: 4203: 4200: 4198: 4195: 4193: 4188: 4186: 4182: 4180: 4177: 4175: 4173: 4169: 4167: 4164: 4162: 4159: 4157: 4154: 4152: 4151:Hexyl nitrite 4149: 4147: 4146:Ethyl nitrite 4144: 4142: 4139: 4137: 4134: 4132: 4126: 4114: 4112: 4108: 4104: 4103: 4100: 4097: 4094: 4092: 4089: 4087: 4084: 4082: 4079: 4077: 4074: 4072: 4069: 4067: 4064: 4062: 4059: 4057: 4054: 4052: 4049: 4047: 4035: 4033: 4030: 4028: 4025: 4023: 4020: 4018: 4015: 4013: 4010: 4008: 4005: 4003: 4000: 3998: 3995: 3993: 3990: 3988: 3985: 3983: 3980: 3978: 3975: 3973: 3970: 3968: 3965: 3963: 3960: 3958: 3954: 3953: 3951: 3947: 3941: 3937: 3927: 3924: 3921: 3920: 3917: 3914: 3912: 3909: 3907: 3904: 3902: 3899: 3897: 3894: 3892: 3889: 3887: 3884: 3882: 3879: 3877: 3874: 3872: 3869: 3866: 3865: 3863: 3861: 3857: 3854: 3852: 3848: 3842: 3839: 3837: 3834: 3832: 3829: 3828: 3826: 3824: 3820: 3816: 3813: 3810: 3803: 3798: 3796: 3791: 3789: 3784: 3783: 3780: 3773: 3772: 3767: 3764: 3761: 3757: 3754: 3752: 3749: 3747: 3729: 3717: 3713: 3709: 3708: 3688: 3684: 3678: 3662: 3661: 3653: 3645: 3641: 3637: 3633: 3629: 3625: 3621: 3617: 3610: 3595: 3589: 3585: 3584: 3576: 3568: 3562: 3558: 3551: 3543: 3539: 3534: 3529: 3525: 3521: 3517: 3513: 3509: 3502: 3486: 3482: 3476: 3461: 3457: 3451: 3443: 3439: 3435: 3431: 3427: 3423: 3422: 3414: 3406: 3402: 3395: 3393: 3391: 3382: 3376: 3357: 3353: 3349: 3345: 3338: 3331: 3315: 3311: 3307: 3300: 3292: 3286: 3282: 3275: 3267: 3261: 3253: 3247: 3243: 3236: 3228: 3224: 3220: 3216: 3212: 3208: 3201: 3193: 3189: 3185: 3181: 3174: 3166: 3162: 3158: 3154: 3147: 3132: 3128: 3121: 3113: 3106: 3104: 3087: 3083: 3079: 3073: 3071: 3062: 3058: 3051: 3043: 3039: 3032: 3025: 3017: 3013: 3006: 2999: 2984: 2980: 2974: 2958: 2954: 2950: 2944: 2936: 2930: 2926: 2919: 2917: 2907: 2902: 2898: 2894: 2890: 2886: 2882: 2875: 2866: 2858: 2854: 2853: 2848: 2842: 2833: 2829: 2825: 2819: 2803: 2799: 2792: 2776: 2772: 2768: 2762: 2753: 2752:Piroglicerina 2749: 2748: 2744: 2740: 2736: 2729: 2721: 2717: 2713: 2706: 2690: 2686: 2680: 2672: 2668: 2663: 2658: 2653: 2648: 2644: 2640: 2636: 2632: 2628: 2621: 2619: 2602: 2598: 2594: 2588: 2580: 2573: 2557: 2553: 2547: 2545: 2543: 2527: 2523: 2517: 2509: 2505: 2499: 2491: 2487: 2480: 2464: 2460: 2454: 2452: 2447: 2437: 2434: 2432: 2429: 2427: 2424: 2422: 2419: 2417: 2414: 2412: 2409: 2407: 2404: 2403: 2396: 2394: 2390: 2386: 2382: 2378: 2373: 2371: 2367: 2361: 2358: 2354: 2344: 2342: 2338: 2334: 2330: 2325: 2323: 2319: 2315: 2311: 2307: 2302: 2298: 2294: 2285: 2281: 2279: 2275: 2271: 2267: 2263: 2257: 2247: 2245: 2241: 2237: 2233: 2229: 2225: 2219: 2217: 2213: 2209: 2205: 2201: 2197: 2192: 2190: 2184: 2182: 2177: 2173: 2169: 2165: 2160: 2158: 2154: 2150: 2146: 2142: 2139: 2135: 2131: 2127: 2123: 2119: 2115: 2111: 2107: 2103: 2101: 2097: 2093: 2089: 2083: 2079: 2075: 2071: 2067: 2057: 2055: 2051: 2047: 2043: 2039: 2035: 2031: 2027: 2023: 2019: 2014: 2012: 2008: 2000: 1997: 1993: 1990: 1986: 1982: 1979: 1975: 1974:sulfuric acid 1970: 1968: 1964: 1960: 1956: 1955:sulfuric acid 1952: 1948: 1947:sulfuric acid 1944: 1943:sulfuric acid 1940: 1936: 1932: 1928: 1924: 1923:sulfuric acid 1920: 1915: 1913: 1904: 1894: 1891: 1883: 1872: 1869: 1865: 1862: 1858: 1855: 1851: 1848: 1844: 1841: –  1840: 1836: 1835:Find sources: 1829: 1825: 1819: 1818: 1813:This article 1811: 1807: 1802: 1801: 1796:Manufacturing 1793: 1791: 1787: 1782: 1778: 1773: 1771: 1720: 1719: 1718: 1710: 1708: 1704: 1700: 1696: 1691: 1689: 1684: 1683:fulminate cap 1680: 1675: 1673: 1669: 1665: 1655: 1653: 1649: 1645: 1641: 1637: 1633: 1629: 1625: 1621: 1617: 1613: 1609: 1599: 1596: 1595: 1590: 1586: 1582: 1577: 1575: 1570: 1568: 1561: 1557: 1553: 1549: 1544: 1539: 1537: 1533: 1529: 1528:San Francisco 1525: 1521: 1517: 1516:Summit Tunnel 1513: 1509: 1504: 1502: 1498: 1494: 1490: 1480: 1476: 1472: 1466: 1464: 1460: 1456: 1451: 1449: 1448:pyroglycerine 1445: 1441: 1437: 1434: 1430: 1420: 1418: 1414: 1410: 1406: 1402: 1398: 1394: 1390: 1386: 1381: 1379: 1375: 1370: 1364: 1362: 1357: 1353: 1349: 1344: 1342: 1338: 1334: 1330: 1326: 1322: 1318: 1314: 1310: 1306: 1302: 1298: 1294: 1290: 1287: 1283: 1279: 1275: 1271: 1267: 1263: 1259: 1255: 1251: 1250:Nitroglycerin 1239: 1232: 1227: 1210: 1192: 1189:(Permissible) 1188: 1184: 1183: 1179: 1178: 1173: 1166: 1159: 1152: 1128: 1125: 1124: 1120: 1119: 1077: 1074: 1070: 1069: 1039: 1036: 1032: 1031: 1028: 1025: 1022: 1018: 1017: 1013: 1008: 1003: 998: 994: 991: 987: 986: 982: 980: 975: 971: 966: 965: 961: 960: 955: 950: 943: 933: 932: 930: 928: 925: 924: 916: 913: 909: 908: 904: 901: 897: 896: 892: 889: 885: 884: 880: 876: 872: 869: 863: 862: 857: 852: 847: 842: 839: 836: 832: 831: 828:Pharmacology 826: 818: 810: 802: 796: 795: 787: 779: 771: 765: 764: 759: 755: 753: 750: 749: 741: 739: 736: 735: 731: 729: 726: 725: 721: 719: 716: 715: 710: 703: 700: 699: 697: 694: 690: 689: 682: 679: 678: 676: 673: 669: 668: 663: 659: 657: 656: 651: 650: 647: 643: 639: 635: 632: 630: 627: 626: 622: 619: 615: 614: 610: 608: 607:Boiling point 605: 604: 600: 598: 597:Melting point 595: 594: 590: 588: 585: 584: 580: 577: 576: 569: 567: 564: 563: 536: 533: 529: 528: 523: 514: 513: 510: 503: 489: 479: 478: 475: 468: 460: 456: 455:DTXSID1021407 452: 451: 449: 439: 435: 434: 430: 428: 425: 424: 417: 413: 412: 410: 408: 405: 404: 397: 393: 392: 390: 384: 380: 379: 375: 374:Nitroglycerin 371: 369: 366: 365: 358: 354: 353: 351: 349: 346: 345: 338: 334: 333: 331: 328: 324: 323: 319: 316: 312: 311: 304: 303: 301: 299: 294: 293: 289: 285: 282: 280: 278:ECHA InfoCard 275: 274: 267: 263: 262: 260: 258: 255: 254: 247: 243: 242: 240: 238: 235: 234: 227: 223: 222: 220: 218: 215: 214: 207: 203: 202: 200: 198: 195: 194: 190: 187: 183: 182: 175: 171: 170: 168: 164: 159: 158: 151: 147: 146: 144: 141: 137: 136: 131: 123: 119: 115: 112: 109: 106: 103: 100: 97: 94: 91: 90: 85: 77: 73: 68: 64: 59: 55: 50: 46: 41: 30: 19: 5099: 5086: 5085: 5061:paraxanthine 5037:beta blocker 4980: 4929: 4907: 4711:-ornithine ( 4644:-ornithine ( 4389: 4368:Feprosidnine 4363:Sydnonimines 4361: 4346: 4343: 4295: 4272: 4269: 4258:nitrosamines 4255: 4190: 4184: 4171: 4128: 4105: 3955: 3922: 3901:GSK-2181236A 3867: 3809:Nitric oxide 3769: 3719:. Retrieved 3715: 3691:. Retrieved 3686: 3677: 3665:. Retrieved 3659: 3652: 3619: 3615: 3609: 3597:. Retrieved 3582: 3575: 3556: 3550: 3515: 3511: 3501: 3489:. Retrieved 3485:the original 3475: 3463:. Retrieved 3459: 3450: 3425: 3419: 3413: 3404: 3375: 3363:. Retrieved 3356:the original 3343: 3330: 3318:. Retrieved 3314:the original 3309: 3299: 3280: 3274: 3241: 3235: 3210: 3206: 3200: 3183: 3179: 3173: 3156: 3152: 3146: 3134:. Retrieved 3130: 3120: 3090:. Retrieved 3086:the original 3081: 3060: 3050: 3041: 3037: 3024: 3015: 3011: 2998: 2986:. Retrieved 2982: 2973: 2961:. Retrieved 2957:the original 2952: 2943: 2924: 2888: 2884: 2874: 2865: 2850: 2841: 2832:the original 2827: 2818: 2806:. Retrieved 2801: 2791: 2779:. Retrieved 2775:the original 2770: 2767:"Emil Nobel" 2761: 2751: 2742: 2738: 2728: 2719: 2715: 2705: 2693:. Retrieved 2689:the original 2679: 2634: 2630: 2605:. Retrieved 2596: 2587: 2578: 2572: 2560:. Retrieved 2556:the original 2529:. Retrieved 2525: 2516: 2508:the original 2498: 2479: 2467:. Retrieved 2463:the original 2374: 2366:vasodilation 2362: 2350: 2337:sublingually 2326: 2290: 2270:nitric oxide 2259: 2220: 2193: 2185: 2161: 2155:. Likewise, 2113: 2106:Alfred Nobel 2104: 2085: 2015: 2011:electrophile 1989:nucleophilic 1971: 1916: 1914:(glycerin). 1909: 1886: 1877: 1867: 1860: 1853: 1846: 1834: 1822:Please help 1817:verification 1814: 1790:kilocalories 1774: 1767: 1716: 1692: 1679:desensitized 1676: 1661: 1612:World War II 1605: 1592: 1581:amyl nitrite 1578: 1571: 1559: 1540: 1518:through the 1505: 1486: 1475:Alfred Nobel 1455:Alfred Nobel 1452: 1447: 1429:black powder 1426: 1405:nitric oxide 1387:as a potent 1382: 1365: 1361:nitric oxide 1356:autoignition 1345: 1339:, used as a 1321:construction 1277: 1273: 1269: 1265: 1261: 1257: 1253: 1249: 1248: 1176: 1122: 1026: 978: 968:Main hazards 957: 927:Legal status 808: 777: 654: 591:1.5931 g/cm 133:Identifiers 121: 117: 113: 87:Other names 5074:simvastatin 4908:Precursors: 4845:epicatechin 4769:Indospicine 4724:-arginine ( 4670:-arginine ( 4605:AR-C 102222 4533:-arginine ( 4520:-arginine ( 4383:Sydnonimine 4116:Nitrite (NO 4099:Trolnitrate 4095:Tenitramine 4037:Nitrate (NO 3923:Inhibitors: 3906:Praliciguat 3886:BAY 60-4552 3881:BAY 41-8543 3876:BAY 41-2272 3693:21 November 3405:MedicineNet 3320:10 November 3213:(1): 1–38. 3136:20 February 2988:20 February 2368:produces a 2329:intravenous 2250:Medical use 2212:James Dewar 2030:nitric acid 1994:atoms. The 1981:nitric acid 1967:nitric acid 1927:nitric acid 1880:August 2024 1632:cordite RDB 1608:World War I 1524:Wells Fargo 1389:vasodilator 1385:in medicine 1369:sensitivity 1021:Signal word 962:(OHS/OSH): 578:Appearance 525:Properties 284:100.000.219 206:CHEBI:28787 5106:Categories 5047:sildenafil 5027:nifedipine 4930:Cofactors: 4919:N-Hydroxy- 4826:N-Hydroxy- 4615:Canavanine 4610:BYK-191023 4429:inhibitors 4358:REC15/2739 4337:V-PYRRO/NO 4027:Nicorandil 3916:Vericiguat 3815:modulators 3491:9 November 2885:The Lancet 2745:: 195–201. 2722:: 247–248. 2469:19 October 2443:References 2387:has set a 2196:ballistite 2110:absorbents 2070:Ballistite 1978:protonated 1963:azeotropic 1850:newspapers 1713:Detonation 1636:Royal Navy 1594:The Lancet 1560:Kieselguhr 1508:California 1493:Geesthacht 1465:, Sweden. 1463:Heleneborg 1341:propellant 1325:demolition 1313:explosives 990:Pictograms 900:Metabolism 801:combustion 665:Structure 629:Solubility 566:Molar mass 416:G59M7S0WS3 327:IUPHAR/BPS 237:ChemSpider 161:3D model ( 140:CAS Number 5087:See also: 5033:Nebivolol 4992:captopril 4914:-Arginine 4855:norvaline 4850:ornithine 4764:GW-273629 4720:N-Methyl- 4666:N-Methyl- 4657:-lysine ( 4529:N-Propyl- 4516:N-Methyl- 4497:ARL-17477 4390:Unsorted: 3940:NO donors 3911:Riociguat 3891:BI-703704 3871:Ataciguat 3812:signaling 3760:torpedoes 3260:cite book 2824:"Krümmel" 2781:6 October 2436:RE factor 2357:tolerance 2353:headaches 2310:afterload 2236:wood pulp 2232:gelignite 2200:guncotton 2151:, and in 2149:quarrying 2114:Kieselgur 2082:Gelignite 2026:oxidation 1976:produces 1567:gelignite 1548:Cwm-y-glo 1501:gunpowder 1481:from 1864 1315:, namely 1286:nitrating 1282:explosive 1111:P302+P352 981:labelling 866:Routes of 770:formation 752:RE factor 623:Slightly 427:UN number 305:200-240-8 297:EC Number 226:ChEMBL730 5054:caffeine 5019:blockers 5010:bosentan 4996:losartan 4813:Arginase 4799:VAS-2381 4794:ONO-1714 4742:Unsorted 4502:Indazole 4408:FR146881 4403:FR144220 4393:Cimlanod 4348:Furoxans 4327:PROLI/NO 4297:NONOates 4247:SNO-t-PA 4111:nitrites 4022:NCX-4215 4017:NCX 4040 4012:NCX-4016 4007:NCX-2216 3957:Nitrates 3946:prodrugs 3721:23 March 3667:23 April 3644:12897126 3636:10779131 3599:23 April 3465:14 April 3365:27 March 3092:23 March 2963:14 April 2695:14 April 2671:16103363 2601:Archived 2492:(NIOSH). 2399:See also 2293:medicine 2210:and Sir 2138:railroad 2126:patented 2122:dynamite 2066:Dynamite 2042:glycerin 2038:glycerin 2018:glycerol 2009:are the 1985:glycerol 1919:glycerol 1912:glycerol 1781:brisance 1552:dynamite 1378:dynamite 1317:dynamite 1289:glycerol 1123:NFPA 704 952:Hazards 835:ATC code 257:DrugBank 191:1802063 5072:(e.g., 5070:Statins 5045:(e.g., 5021:(e.g., 5008:(e.g., 4990:(e.g., 4840:ginseng 4789:NXN-462 4784:NCX-456 4774:KD-7040 4754:CKD-712 4487:A-84643 4353:Furoxan 4252:SNO-vWF 4002:NCX-466 3851:Targets 3542:4998847 3533:1798737 3442:3917597 3348:Bibcode 3346:: 151. 2906:5901592 2808:4 March 2662:1189320 2639:Bibcode 2531:16 July 2486:"#0456" 2306:preload 2204:cordite 2141:tunnels 2134:highway 2088:tonnage 2074:Cordite 1864:scholar 1703:acetone 1699:ethanol 1497:Hamburg 1442:at the 1433:chemist 1423:History 1231:what is 1229: ( 1201:mg/m) 893:<1% 853: ( 851:C05AE01 849:) 843: ( 841:C01DA02 823:MJ⋅mol 792:kJ⋅mol 646:alcohol 642:benzene 634:Acetone 587:Density 571:227.085 383:PubChem 320:165859 266:DB00727 150:55-63-0 4901:Others 4860:lysine 4423:Enzyme 4398:FK-409 4312:GLO/NO 4263:SIN-1A 3642:  3634:  3590:  3563:  3540:  3530:  3440:  3287:  3248:  3227:812687 3225:  3061:Analog 2931:  2903:  2669:  2659:  2607:9 July 2562:9 July 2240:sodium 2238:, and 2145:mining 2143:, for 2116:", or 2098:, and 2080:, and 1992:oxygen 1866:  1859:  1852:  1845:  1837:  1644:Dorset 1628:tonnes 1329:mining 1327:, and 1276:), or 1226:verify 1223:  1199:  1197:ppm (2 1195:  1027:Danger 940: 919:  905:Liver 821:  819:−1.529 790:  744:  660:2.154 509:SMILES 357:D00515 217:ChEMBL 70:Names 4933:NADPH 4728:-NMA) 4715:-NIO) 4674:-NMA) 4661:-NIL) 4648:-NIO) 4590:AEITU 4585:1400W 4537:-NPA) 4524:-NMA) 4511:-NIO) 4197:LA810 3823:Forms 3689:. CDC 3640:S2CID 3359:(PDF) 3340:(PDF) 3044:: 71. 3034:(PDF) 3018:: 70. 3008:(PDF) 2331:use, 2278:ALDH2 2176:shale 2174:from 1999:group 1996:nitro 1961:—and 1951:oleum 1871:JSTOR 1857:books 1761:+ 0.5 1754:+ 1.5 1746:+ 2.5 1705:, or 1642:, in 1495:near 1413:ALDH2 1393:heart 1297:ester 1291:with 1266:nitro 1193:C 0.2 1177:NIOSH 756:1.50 742:7,700 732:High 722:High 638:ether 474:InChI 197:ChEBI 163:JSmol 122:alpha 118:alpha 114:alpha 104:Nitro 4948:Heme 4875:CAMK 4694:eNOS 4684:TRIM 4635:MITU 4630:IPTU 4625:EITU 4562:iNOS 4552:TRIM 4449:nNOS 4317:JS-K 4185:tert 3723:2005 3695:2015 3669:2013 3632:PMID 3601:2013 3588:ISBN 3561:ISBN 3538:PMID 3493:2009 3467:2018 3438:PMID 3367:2015 3322:2009 3285:ISBN 3266:link 3246:ISBN 3223:PMID 3138:2024 3094:2005 2990:2024 2965:2018 2929:ISBN 2810:2024 2783:2008 2697:2018 2667:PMID 2609:2024 2564:2024 2533:2024 2471:2016 2170:and 2136:and 2124:and 2050:lead 2046:iron 1972:The 1843:news 1672:PETN 1670:and 1610:and 1399:and 1115:P410 1107:P280 1103:P271 1099:P270 1095:P264 1091:P260 1087:P250 1083:P243 1079:P210 1065:H370 1061:H331 1057:H311 1053:H301 1049:H241 1045:H205 1041:H202 921:min 788:−370 746:m/s 653:log 407:UNII 396:4510 368:MeSH 348:KEGG 337:7053 246:4354 4961:CaM 4943:FMN 4938:FAD 4888:W-7 4821:ABH 4600:AMT 4440:NOS 3926:ODQ 3860:sGC 3768:at 3624:doi 3528:PMC 3520:doi 3430:doi 3215:doi 3188:doi 3161:doi 2901:PMC 2893:doi 2857:PBS 2657:PMC 2647:doi 2635:102 2291:In 2242:or 2181:TNT 2172:gas 2168:oil 2100:HMX 2096:RDX 2092:TNT 2048:or 1987:'s 1826:by 1786:mol 1777:TNT 1770:mol 1739:→ 3 1668:RDX 1630:of 1477:'s 1274:GTN 1264:), 1262:TNG 1187:PEL 979:GHS 856:WHO 846:WHO 812:298 781:298 443:EPA 386:CID 107:TNG 101:GTN 5108:: 5025:: 5002:ET 4994:, 4974:Ca 4953:BH 4360:; 4260:): 4254:; 4189:; 4133:): 4127:; 3714:. 3685:. 3638:. 3630:. 3620:27 3618:. 3536:. 3526:. 3514:. 3510:. 3458:. 3436:. 3426:55 3424:. 3403:. 3389:^ 3342:. 3308:. 3262:}} 3258:{{ 3221:. 3209:. 3184:92 3182:. 3157:64 3155:. 3129:. 3102:^ 3080:. 3069:^ 3059:. 3042:16 3040:. 3036:. 3016:16 3014:. 3010:. 2981:. 2951:. 2915:^ 2899:. 2887:. 2883:. 2855:. 2849:. 2826:. 2800:. 2769:. 2743:10 2720:24 2718:. 2665:. 2655:. 2645:. 2633:. 2629:. 2617:^ 2599:. 2595:. 2541:^ 2524:. 2488:. 2450:^ 2395:. 2324:. 2191:. 2183:. 2094:, 2076:, 2072:, 2068:, 2013:. 1741:CO 1701:, 1674:. 1558:(" 1323:, 1268:, 1254:NG 1113:, 1109:, 1105:, 1101:, 1097:, 1093:, 1089:, 1085:, 1081:, 1063:, 1059:, 1055:, 1051:, 1047:, 1043:, 983:: 942:S3 936:AU 881:: 859:) 804:(Δ 773:(Δ 644:, 640:, 636:, 5076:) 5063:) 5056:) 5049:) 5039:) 5035:( 5029:) 5012:) 5004:B 4998:) 4986:/ 4968:2 4966:O 4955:4 4921:L 4912:L 4828:L 4726:L 4722:L 4713:L 4709:L 4672:L 4668:L 4659:L 4655:L 4646:L 4642:L 4535:L 4531:L 4522:L 4518:L 4509:L 4431:) 4427:( 4365:: 4350:: 4276:: 4172:n 4125:) 4121:2 4113:: 4109:/ 4046:) 4042:3 3959:: 3948:) 3944:( 3801:e 3794:t 3787:v 3745:9 3743:O 3741:3 3739:N 3737:5 3735:H 3733:3 3725:. 3697:. 3671:. 3646:. 3626:: 3603:. 3569:. 3544:. 3522:: 3516:3 3495:. 3469:. 3444:. 3432:: 3407:. 3383:. 3369:. 3350:: 3324:. 3293:. 3268:) 3254:. 3229:. 3217:: 3211:4 3194:. 3190:: 3167:. 3163:: 3140:. 3096:. 2992:. 2967:. 2937:. 2909:. 2895:: 2889:1 2859:. 2836:. 2812:. 2785:. 2699:. 2673:. 2649:: 2641:: 2611:. 2566:. 2535:. 2473:. 2276:( 2003:2 1953:— 1893:) 1887:( 1882:) 1878:( 1868:· 1861:· 1854:· 1847:· 1820:. 1763:O 1758:2 1756:N 1752:O 1750:2 1748:H 1743:2 1736:9 1734:O 1732:3 1730:N 1728:5 1726:H 1724:3 1722:C 1563:" 1411:( 1372:( 1272:( 1260:( 1252:( 1221:Y 1164:4 1157:2 1150:3 938:: 917:3 814:) 809:H 806:c 783:) 778:H 775:f 655:P 559:9 556:O 553:3 550:N 547:5 544:H 541:3 538:C 445:) 441:( 165:) 120:, 116:, 31:. 20:)

Index

Nitroglycerine
Nitroglycerin (medication)
Skeletal formula of zwitterionic nitroglycerin
Ball and stick model of nitroglycerin
Spacefill model of nitroglycerin
Preferred IUPAC name
CAS Number
55-63-0
JSmol
Interactive image
Beilstein Reference
ChEBI
CHEBI:28787
ChEMBL
ChEMBL730
ChemSpider
4354
DrugBank
DB00727
ECHA InfoCard
100.000.219
Edit this at Wikidata
EC Number
Gmelin Reference
IUPHAR/BPS
7053
KEGG
D00515
MeSH
Nitroglycerin

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