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Nitroglycerin

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2328:. Some forms of nitroglycerin last much longer in the body than others. Nitroglycerin as well as the onset and duration of action of each form is different. The sublingual or tablet spray of nitroglycerin has a two minute onset and twenty five minute duration of action. The oral formulation of nitroglycerin has a thirty five minute onset and a duration of action of 4–8 hours. The transdermal patch has an onset of thirty minutes and a duration of action of ten to twelve hours. Continuous exposure to nitrates has been shown to cause the body to stop responding normally to this medicine. Experts recommend that the patches be removed at night, allowing the body a few hours to restore its responsiveness to nitrates. Shorter-acting preparations of nitroglycerin can be used several times a day with less risk of developing tolerance. Nitroglycerin was first used by 43: 448: 277: 2297:(volume of blood in the heart after filling); this is thought to be its primary mechanism of action. By decreasing preload, the heart has less blood to pump, which decreases oxygen requirement since the heart does not have to work as hard. Additionally, having a smaller preload reduces the ventricular transmural pressure (pressure exerted on the walls of the heart), which decreases the compression of heart arteries to allow more blood to flow through the heart. At higher doses, it also dilates arteries, thereby reducing 996: 1892: 1539:. The explosion led to the loss of six lives, many injuries and much damage to the village. Little trace was found of the two horses. The UK Government was so alarmed at the damage caused and what could have happened in a city location (these two tons were part of a larger load coming from Germany via Liverpool) that they soon passed the Nitro-Glycerine Act of 1869. Liquid nitroglycerin was widely banned elsewhere, as well, and these legal restrictions led to Alfred Nobel and his company's developing 52: 1001: 986: 34: 991: 1128: 1124: 1795: 2045:, has an emergency trap door at its base, which hangs over a large pool of very cold water and into which the whole reaction mixture (called the charge) can be dumped to prevent an explosion, a process referred to as drowning. If the temperature of the charge exceeds about 30 °C (86 °F) (actual value varying by country) or brown fumes are seen in the nitrator's vent, then it is immediately drowned. 1460: 2273: 1206: 1129: 1655:, with physical shock causing it to explode. If it has not been adequately purified during manufacture it can degrade over time to even more unstable forms. This makes nitroglycerin highly dangerous to transport or use. In its undiluted form, it is one of the world's most powerful explosives, comparable to the more recently developed 2210:
Smokeless powders were originally developed using nitrocellulose as the sole explosive ingredient. Therefore, they were known as single-base propellants. A range of smokeless powders that contains both nitrocellulose and nitroglycerin, known as double-base propellants, were also developed. Smokeless
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or a rifle ball when in that condition but on the other hand it appears to be more liable to explode on breaking, crushing, tamping, etc." Frozen nitroglycerine is much less energetic than liquid, and so must be thawed before use. Thawing it out can be extremely sensitizing, especially if impurities
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For workers in nitroglycerin (NTG) manufacturing facilities, the effects of withdrawal sometimes include "Sunday heart attacks" in those experiencing regular nitroglycerin exposure in the workplace, leading to the development of tolerance for the venodilating effects. Over the weekend, the workers
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in 1879. A few months before his death in 1896, Alfred Nobel was prescribed nitroglycerin for this heart condition, writing to a friend: "Isn't it the irony of fate that I have been prescribed nitro-glycerin, to be taken internally! They call it Trinitrin, so as not to scare the chemist and the
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Due to its high boiling point and subsequent low vapor pressure (0.00026 mmHg at 20 °C), pure nitroglycerin has practically no odor at room temperature, with a sweet and burning taste when ingested. Unintentional detonation may ensue when dropped, shaken, lit on fire, rapidly heated, exposed to
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caused by inadequate flow of blood and oxygen to the heart and as a potent antihypertensive agent. Nitroglycerin corrects the imbalance between the flow of oxygen and blood to the heart and the heart's energy demand. There are many formulations on the market at different doses. At low doses,
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temperature of 270 °C instead. With a melting point of 12.8 °C, the chemical is almost always encountered as a thick and viscous fluid, changing to a crystalline solid when frozen. Although the pure compound itself is colorless, in practice the presence of
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to and dependence on nitroglycerin after long-term exposure. Although rare, withdrawal can be fatal;symptoms include chest pain and other heart problems. These symptoms may be relieved with re-exposure to nitroglycerin or other suitable organic nitrates.
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formations. The technique involves displacing and detonating nitroglycerin in natural or hydraulically induced fracture systems, or displacing and detonating nitroglycerin in hydraulically induced fractures followed by wellbore shots using pelletized
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powders were originally supplied only for military use, but they were also soon developed for civilian use and were quickly adopted for sports. Some are known as sporting powders. Triple-base propellants contain nitrocellulose, nitroglycerin, and
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explosive, which is to say, it has excellent shattering ability. The heat liberated during detonation raises the temperature of the gaseous byproducts to about 5,000 °C (9,000 °F). With a standard enthalpy of explosive decomposition of
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to exploding is responsible for numerous devastating industrial accidents throughout its history. The chemical's characteristic reactivity may be reduced through the addition of desensitizing agents, which makes it less likely to explode. Clay
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resulted in an explosion on the Town Moor that killed eight people. In June 1869, two one-ton wagons loaded with nitroglycerin, then known locally as Powder-Oil, exploded in the road at the North Wales village of
4235: 1145: 4401: 2191:. He patented it in 1887. Ballistite was adopted by a number of European governments, as a military propellant. Italy was the first to adopt it. The British government and the Commonwealth governments adopted 1670:" by freezing it at a temperature below 45 to 55 °F (7 to 13 °C) depending on its purity. Its sensitivity to shock while frozen is somewhat unpredictable: "It is more insensitive to the shock from a 4588: 3914: 1009: 2175:
Nitroglycerin has an advantage over some other high explosives that on detonation it produces practically no visible smoke. Therefore, it is useful as an ingredient in the formulation of various kinds of
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and killing 15 people. This led to a complete ban on the transportation of liquid nitroglycerin in California. The on-site manufacture of nitroglycerin was thus required for the remaining hard-rock
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mixture is added slowly to the reaction vessel containing the mixed acid (not acid to glycerin). The nitrator is cooled with cold water or some other coolant mixture and maintained throughout the
1558:" (1875), were formed by mixing nitroglycerin with other inert absorbents, and many combinations were tried by other companies in attempts to get around Nobel's tightly held patents for dynamite. 966: 2013:(i.e., heat is produced), as usual for mixed-acid nitrations. If the mixture becomes too hot, it results in a runaway reaction, a state of accelerated nitration accompanied by the destructive 4672: 4540: 1580:. He began treating his patients with small diluted doses of nitroglycerin in 1878, and this treatment was soon adopted into widespread use after Murrell published his results in the journal 1698:. The nitroglycerin may have to be extracted from the desensitizer chemical to restore its effectiveness before use, for example by adding water to draw off ethanol used as a desensitizer. 4240: 162: 2492: 4210: 2033:
addition at about 22 °C (72 °F), hot enough for esterification to occur at a fast rate but cold enough to avoid runaway reaction. The nitrator vessel, often constructed of
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called "Blasting Oil", but this was extremely unstable and difficult to handle, as evidenced in numerous catastrophes. The buildings of the Krümmel factory were destroyed twice.
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it in 1867. It was supplied ready for use in the form of sticks, individually wrapped in greased waterproof paper. Dynamite and similar explosives were widely adopted for
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per gram, or 6.23 kJ/g, making nitroglycerin 49% more energetic on a mass basis than the standard definitional value assigned to TNT (precisely 1 kcal/g).
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Kaplan, K. J.; Taber, M.; Teagarden, J. R.; Parker, M.; Davison, R. (1985). "Association of methemoglobinemia and intravenous nitroglycerin administration".
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for the heat of formation of condensed phase nitroglycerin gives 1414 kJ/mol released if forming water vapor, and 1524 if forming liquid water.
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On Christmas Day 1867, an attempt to dispose of nine canisters of Blasting Oil that had been illegally stored at the White Swan Inn in the centre of
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Chen, Z.; Foster, M. W.; Zhang, J.; Mao, L.; Rockman, H. A.; Kawamoto, T.; Kitagawa, K.; Nakayama, K. I.; Hess, D. T.; Stamler, J. S. (2005).
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People can be exposed to nitroglycerin in the workplace by breathing it in, skin absorption, swallowing it, or eye contact. The
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known as "NG head" or "bang head". These headaches can be severe enough to incapacitate some people; however, humans develop a
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or another polynitrate may be added to lower the melting point and thereby avoid the necessity of thawing frozen explosive.
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Nitroglycerin is an oily liquid that explodes when subjected to heat, shock, or flame. The main use of nitroglycerin, by
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of the United Kingdom in 1889. The original Cordite Mk I consisted of 58% nitroglycerin, 37% guncotton, and 5.0%
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Chemically "desensitizing" nitroglycerin is possible to a point where it can be considered about as "safe" as modern
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per week. This amount required at least 336 tonnes of nitroglycerin per week (assuming no losses in production). The
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and a molecular weight of 227.0865 g/mol, nitroglycerin has a specific explosive energy density of 1.488 
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Marsh, N.; Marsh, A. (2000). "A short history of nitroglycerine and nitric oxide in pharmacology and physiology".
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in German) found in the Krümmel hills. Similar mixtures, such as "dualine" (1867), "lithofracteur" (1869), and "
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and water is produced. This is different from an electrophilic aromatic substitution reaction in which
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As is the case for many other explosives, nitroglycerin becomes more and more prone to exploding (i.e.
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The detonation velocity of nitroglycerin is 7820 meters per second, which is about 113% the speed of
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of 0.1 mg/m skin exposure over an 8-hour workday. At levels of 75 mg/m, nitroglycerin is
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Nitroglycerin in three different forms: intravenous, sublingual spray, and the nitroglycerin patch.
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Nitroglycerin belongs to a group of drugs called nitrates, which includes many other nitrates like
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public." The medical establishment also used the name "glyceryl trinitrate" for the same reason.
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developed the use of nitroglycerin as a blasting explosive by mixing nitroglycerin with inert
4931: 4428: 4272: 3444: 2700: 1520: 1389: 1023: 978: 660: 641: 2945: 4277: 4230: 4054: 3980: 3970: 3336: 2627: 2616:"An essential role for mitochondrial aldehyde dehydrogenase in nitroglycerin bioactivation" 2419: 2414: 2404: 2294: 2250: 2152: 1852: 1604: 1508: 1356:
sunlight and ozone, subjected to sparks and electrical discharges, or roughly handled. Its
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Di Carlo, F. J. (1975). "Nitroglycerin Revisited: Chemistry, Biochemistry, Interactions".
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The heat released can be calculated from the heats of formation. Using −371 kJ/
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experimented with the use of nitroglycerin to alleviate angina pectoris and to reduce the
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impurities left over during production tends to give it a slight yellowish tint.
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Nitroglycerin was the first practical explosive produced that was stronger than
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to treat angina attacks in 1878, with the discovery published that same year.
1934:. More often, this mixture is attained by the cheaper method of mixing fuming 1891: 1565:, which increases the viscosity of the mix, are commonly known as "gelatins". 1079: 5094: 4972: 4721: 4530: 4159: 4139: 4134: 4119: 3180: 3153: 2345: 1995: 1962: 1943: 1935: 1931: 1911: 1620: 1516: 1336: 1091: 626: 595: 585: 265: 3747:
Detailed and horrific stories of the historical use of nitroglycerin-filled
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cGMP preferring PDE inhibitors (e.g., sildenafil, paraxanthine, tadalafil)
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Colorless or pale yellow, oily liquid or tetraclinic/orthorhombic crystal
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lose the tolerance, and when they are re-exposed on Monday, the drastic
2207:. Ballistite and cordite were both manufactured in the form of "cords". 1137: 1099: 254: 5035: 5015: 4949: 4603: 4020: 4015: 3904: 3884: 3701:"Nitroglycerine! Terrible Explosion and Loss of Lives in San Francisco" 2325: 2184: 2141: 2058: 1966: 1951: 1624: 1582: 1496: 1481: 1451: 1329: 1313: 1144: 888: 617: 554: 315: 285: 225: 3140:"Zusammensetzung der Zuckerasche" [Composition of sugar ash]. 2361:, dizziness, and a headache. This is referred to as "Monday disease." 1706:
When nitroglycerin explodes, the products after cooling are given by:
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Infrequent exposure to high doses of nitroglycerin can cause severe
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Except where otherwise noted, data are given for materials in their
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nitroglycerin dilates veins more than arteries, thereby reducing
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in Germany and built an isolated factory in the Krümmel hills of
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under conditions appropriate to the formation of the nitric acid
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Assembly of Life Sciences (U.S.) Advisory Center on Toxicology.
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Nitroglycerin was adopted as a commercially useful explosive by
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InChI=1S/C3H5N3O9/c7-4(8)13-1-3(15-6(11)12)2-14-5(9)10/h3H,1-2H2
5058: 4954: 4848: 4411: 3390:"nitroglycerin, Nitro-Bid: Drug Facts, Side Effects and Dosing" 2133: 2129: 1980: 1632: 1495:
In April 1866, several crates of nitroglycerin were shipped to
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InChI=1/C3H5N3O9/c7-4(8)13-1-3(15-6(11)12)2-14-5(9)10/h3H,1-2H2
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Nitroglycerin is available in tablets, ointment, solution for
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Early in its history, liquid nitroglycerin was found to be "
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Nitroglycerin can be produced by acid-catalyzed nitration of
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Large quantities of nitroglycerin were manufactured during
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have used dynamite for construction and demolition work.
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Clinical Environmental Health and Toxic Exposures: Latex
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On p. 197, Sobrero names nitroglycerin "pyroglycerine":
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and warned vigorously against its use as an explosive.
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Nitroxyl anion (NO; oxonitrate(1-), hyponitrite anion)
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North Wales Daily Post newspaper of October 14th 2018.
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Clinical and Experimental Pharmacology and Physiology
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Memorie della Reale Accademia delle Scienze di Torino
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National Institute for Occupational Safety and Health
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National Institute for Occupational Safety and Health
2269:), and nitric oxide is a potent natural vasodilator. 1511:. One of the remaining crates exploded, destroying a 1053: 3705:
Central Pacific Railroad Photographic History Museum
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in 1867. This was made by mixing nitroglycerin with
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Methylamine hexamethylene methylamine/NO (MAHMA/NO)
2235:. This was an early, low-cost, flexible explosive. 1819:. Unsourced material may be challenged and removed. 1380:(causing dilation of the vascular system) to treat 324: 3575:. Lippincott Williams & Wilkins. p. 264. 3272:(3rd ed.). USA: Academic Press. p. 569. 3101:"Tales of Destruction...Is Nitroglycerin In This?" 2613: 2493:"Hazard Rating Information for NFPA Fire Diamonds" 1906:The industrial manufacturing process often reacts 1646: 4125:Amyl nitrite (isoamyl nitrite, isopentyl nitrite) 3470:"Nitroglycerin for angina, February 1997, Vol. 7" 3027:Proceedings of the Lake Superior Mining Institute 3001:Proceedings of the Lake Superior Mining Institute 862:Intravenous, by mouth, under the tongue, topical 5092: 3569:Sullivan, John B. Jr.; Krieger, Gary R. (2001). 2151:Nitroglycerin has been used in conjunction with 1041: 383: 3986:Naproxcinod (nitronaproxen; AZD-3582, HCT-3012) 3568: 2870:"Nitroglycerin as a remedy for angina pectoris" 2620:Proceedings of the National Academy of Sciences 1372:Nitroglycerin has been used for over 130 years 1126: 600:218 °C (424 °F; 491 K) Explodes 137: 3562: 3323: 1269:, is a dense, colorless or pale yellow, oily, 1049: 4402:N-Acetyl-N-acetoxy-4-chlorobenzenesulfonamide 3961:Ethylene glycol dinitrate (EGDN; nitroglycol) 3782: 3596: 2907: 2905: 2366:Occupational Safety and Health Administration 3740:CDC - NIOSH Pocket Guide to Chemical Hazards 3652:. National Academies. p. 115. NAP:11288 3333:Shale Oil, Tar Sand and Related Fuel Sources 3253:: CS1 maint: multiple names: authors list ( 3094: 3092: 3046:"Tales of Destruction...Thawing Can Be Hell" 2025:gas at high risk of an explosion. Thus, the 1332:in artillery and firearms since the 1880s. 16:For the use of this chemical as a drug, see 2570:(97th ed.). CRC Press. pp. 3–540. 1590: 1572:helped alleviate chest pain, the physician 3789: 3775: 3639: 3602: 3543: 3295:"Alfred Nobel and the History of Dynamite" 2902: 2880:(2890): 80–81, 113–115, 151–152, 225–227. 2442: 2440: 1910:with a nearly 1:1 mixture of concentrated 1651:In its undiluted form, nitroglycerin is a 1365:) is an example of such an agent, forming 590:12.8 °C (55.0 °F; 285.9 K) 446: 275: 233: 4145:Isobutyl nitrite (2-methylpropyl nitrite) 4055:Nitroglycerin (glyceryl trinitrate (GTN)) 3520: 3494: 3089: 2893: 2649: 2639: 2195:instead, which had been developed by Sir 1879:Learn how and when to remove this message 1675:are present or the warming is too rapid. 1435:. Sobrero initially called his discovery 1404:) in 2002. Nitroglycerin is available in 403: 3317: 3193: 3037: 2960: 2785:Ramsay, Sir William (28 December 1907). 2473:NIOSH Pocket Guide to Chemical Hazards. 2382:immediately dangerous to life and health 2271: 1890: 1629:Royal Navy Cordite Factory, Holton Heath 1611:, the largest propellant factory in the 1458: 4221:S-Nitrosocysteine (SNC, CysNO, SNO-Cys) 4211:S-Nitroso-N-valerylpenicillamine (SNVP) 3324:Miller, J. S.; Johansen, R. T. (1976). 3229:Lewis, Richard J., Sr (15 March 2007). 3113: 3061: 3059: 2911: 2867: 2721: 2698: 2437: 2091:have largely replaced it in munitions. 1603:for use as military propellants and in 1499:, three of which were destined for the 442: 361: 253: 5093: 4206:S-Nitroso-N-acetylpenicillamine (SNAP) 4080:Sodium trioxodinitrate (Angeli's salt) 3676:NIOSH Pocket Guide to Chemical Hazards 3267: 3231:Hawley's Condensed Chemical Dictionary 3114:Informatics, NIST Office of Data and. 3017: 2991: 2335: 2136:, for clearing farmland of stumps, in 266: 3770: 3228: 3018:Hurter, Charles S. (22 August 1911). 3011: 2992:Hurter, Charles S. (22 August 1911). 2985: 2582:"Nitroglycerin, desensitized, liquid" 2568:CRC Handbook of Chemistry and Physics 1954:nitric acid (consisting of about 70% 474:Key: SNIOPGDIGTZGOP-UHFFFAOYSA-N 213: 193: 5041:non-selective PDE inhibitors (e.g., 3825:Nitric oxide (NO; nitrogen monoxide) 3544:Amdur, Mary O.; Doull, John (1991). 3056: 2787:"The Manufacture of High Explosives" 2535: 2533: 2531: 2049:Use as an explosive and a propellant 1817:adding citations to reliable sources 1788: 1420:. It was synthesized by the Italian 1308:, and as such it is employed in the 843: 833: 4065:Pentaerithrityl tetranitrate (PETN) 3951:Diethylene glycol dinitrate (DEGDN) 3537: 3098: 3043: 2968:"Is Nitroglycerine In This? Page 5" 2674:"Unknown, behind paywall, archived" 2592:from the original on 26 August 2023 1523:required for the completion of the 484:Key: SNIOPGDIGTZGOP-UHFFFAOYAR 374: 344: 13: 4970:Indirect/downstream NO modulators: 4738:Asymmetric dimethylarginine (ADMA) 3847: 3292: 2565: 2219:. Blasting gelatin, also known as 1408:, sprays, ointments, and patches. 1288:. Chemically, the substance is an 1122: 14: 5147: 5101:Aldehyde dehydrogenase inhibitors 4768:Nitroarginine methyl ester (NAME) 4231:S-Nitrosoglutathione (GSNO, SNOG) 4201:S-Nitroso-N-acetylcysteine (SNAC) 4075:Propylene glycol dinitrate (PGDN) 3830:Nitrosonium (NO; nitrosyl cation) 3693: 3387: 2528: 2187:, by combining nitroglycerin and 1918:. This can be produced by mixing 1273:liquid most commonly produced by 924: 672:Trigonal planar at N7, N8, and N9 3745:The Tallini Tales of Destruction 3617:10.1046/j.1440-1681.2000.03240.x 3169:Annalen der Chemie und Pharmacie 3142:Annalen der Chemie und Pharmacie 2017:of organic materials by the hot 1990:is thus added as an ester C−O−NO 1793: 1784: 1320:industries. It is combined with 1204: 999: 994: 989: 984: 538: 532: 50: 41: 32: 4296:Diethylenetriamine/NO (DETA/NO) 3664: 3546:Casarett and Doull's Toxicology 3495:Smith, E.; Hart, F. D. (1971). 3488: 3462: 3437: 3400: 3362: 3286: 3268:Wexler, Philip (7 April 2014). 3261: 3222: 3187: 3160: 3133: 3107: 2930: 2861: 2852: 2828: 2805: 2748: 2715: 2692: 1972:species, which are attacked by 1804:needs additional citations for 1647:Instability and desensitization 1525:First transcontinental railroad 1200:(at 25 °C , 100 kPa). 4496:N-(1-Iminoethyl)-L-ornithine ( 3410:American Journal of Cardiology 2666: 2574: 2559: 2503: 2485: 2466: 2305:, increase of heart rate, and 2238: 1958:, with the rest being water). 1476:One year later, Nobel founded 948:Occupational safety and health 544: 526: 69:Propane-1,2,3-triyl trinitrate 1: 5079:Receptor/signaling modulators 4748:Guanidinoethyldisulfide (GED) 3966:Isosorbide mononitrate (ISMN) 3956:Erythritol tetranitrate (ETN) 2886:10.1016/s0140-6736(02)46032-1 2543:. 16 May 2013. Archived from 2431: 2261:in the body by mitochondrial 2021:and the release of poisonous 1701: 1686:, such as by the addition of 1568:Following the discovery that 1561:Dynamite mixtures containing 1193: 1169:(US health exposure limits): 690:Tetrahedral at C1, C2, and C3 420:0143, 0144, 1204, 3064, 3319 4216:S-Nitrosocaptopril (SNO-Cap) 4045:Nitroflurbiprofen (HCT-1026) 4040:Nitroatorvastatin (NCX-6560) 3760:The Periodic Table of Videos 3423:10.1016/0002-9149(85)90324-8 2245:Medical use of nitroglycerin 2183:Alfred Nobel then developed 2155:, a process used to recover 669:Tetragonal at C1, C2, and C3 7: 4691:Aminoguanidine (pimagedine) 4584:Aminoguanidine (pimagedine) 4481:Aminoguanidine (pimagedine) 4245:N-Nitroso compounds (e.g., 4060:Nitropravastatin (NCX-6550) 3971:Isosorbide dinitrate (ISDN) 3751:to restart petroleum wells. 2387: 2121:tasks, such as in drilling 2041:and generally stirred with 1637:Canadian Explosives Limited 1627:had its own factory at the 81:1,2,3-Tris(nitrooxy)propane 10: 5152: 4977:AT-II receptor antagonists 4722:Nitroarginine (NNA, NOARG) 4559:1-Amino-2-hydroxyguanidine 4531:Nitroarginine (NNA, NOARG) 4278:Sodium nitroprusside (SNP) 3763:(University of Nottingham) 3548:(4th ed.). Elsevier. 3270:Encyclopedia of Toxicology 2378:recommended exposure limit 2370:permissible exposure limit 2242: 2109:. He named this explosive 2052: 1607:work. During World War I, 1411: 693:Dihedral at N7, N8, and N9 18:Nitroglycerin (medication) 15: 5072: 4889: 4862: 4800: 4730: 4681: 4549: 4436: 4427: 4410: 3927: 3838: 3810: 3208:10.3109/03602537508993747 2914:Drug Discovery: A History 2868:Murrell, William (1879). 2722:Sobrero, Ascanio (1849). 2699:Sobrero, Ascagne (1847). 2400:Ethylene glycol dinitrate 2368:has set the legal limit ( 2324:, or sprays administered 1677:Ethylene glycol dinitrate 1337:spontaneous decomposition 1194: 1163: 965: 945: 940: 866: 816: 749: 700: 653: 513: 493: 458: 121: 75: 63: 58: 49: 40: 31: 5126:Sugar alcohol explosives 4456:3-Chloro-5-nitroindazole 4291:Diethylamine/NO (DEA/NO) 4263:Metal nitrosyl complexes 4191:S-Nitrosoalbumin (SNALB) 3885:Cinaciguat (BAY 58-2667) 3716:– 1866 Newspaper article 3181:10.1002/jlac.18540920309 3154:10.1002/jlac.18480640364 3071:Encyclopaedia Britannica 2912:Sneader, Walter (2005). 1920:white fuming nitric acid 1591:Wartime production rates 1501:Central Pacific Railroad 1478:Alfred Nobel and Company 1282:white fuming nitric acid 1062:Precautionary statements 5048:PDE9 inhibitors (e.g., 4536:Pentamidine isethionate 4446:3-Bromo-7-nitroindazole 4333:Heterocyclic compounds: 3857:Activators/stimulators: 3501:British Medical Journal 3445:"IntraMed – Bienvenido" 3196:Drug Metabolism Reviews 3167:"Ueber Nitroglycerin". 3103:. Analog Services, Inc. 3052:. Analog Services, Inc. 2916:. John Wiley and Sons. 2641:10.1073/pnas.0503723102 2395:Erythritol tetranitrate 2307:orthostatic hypotension 2288:, a painful symptom of 1895:Nitroglycerin synthesis 1509:Sierra Nevada Mountains 1429:Théophile-Jules Pelouze 1427:in 1846, working under 1292:compound rather than a 1267:1,2,3-trinitroxypropane 84:1,2,3-Trinitroxypropane 5005:L-Type calcium channel 3513:10.1136/bmj.3.5775.632 2586:CAMEO Chemicals | NOAA 2290:ischemic heart disease 2277: 2263:aldehyde dehydrogenase 2255:isosorbide mononitrate 1924:red fuming nitric acid 1896: 1471: 1398:aldehyde dehydrogenase 1133: 505:C(C(CO(=O))O(=O))O(=O) 5106:Disulfiram-like drugs 4609:Cindunistat (SD-6010) 4564:2-Ethylaminoguanidine 4321:Spermine/NO (SPER/NO) 4118:O-Nitroso compounds ( 3649:Toxicological Reports 2275: 1894: 1615:, produced about 800 1521:drilling and blasting 1462: 1390:chronic heart failure 1324:to form double-based 1132: 661:Coordination geometry 4995:receptor antagonists 4668:Ronopterin (VAS-203) 4367:Molsidomine (SIN-10) 4288:(diazeniumdiolates): 4268:Roussin's black salt 3981:Mannitol hexanitrate 3175:(3): 305–306. 1854. 3148:(3): 398–399. 1848. 3077:on 12 September 2002 2499:on 17 February 2015. 2420:Xylitol pentanitrate 2415:Tetranitratoxycarbon 2405:Mannitol hexanitrate 2251:isosorbide dinitrate 2153:hydraulic fracturing 1813:improve this article 1773:−1414 kJ/ 1605:military engineering 1384:conditions, such as 1341:atmospheric pressure 1115:(fire diamond) 901:Biological half-life 717:Friction sensitivity 65:Preferred IUPAC name 5116:Explosive chemicals 4362:Linsidomine (SIN-1) 4259:Nitrosyl compounds: 4226:S-Nitrosodiclofenac 4196:S-Nitrosated AR545C 4181:S-Nitroso compounds 3341:1976sots.rept...98M 2942:beyonddiscovery.org 2841:American Experience 2791:Scientific American 2632:2005PNAS..10212159C 2626:(34): 12159–12164. 2336:Industrial exposure 2322:transdermal patches 2011:exothermic reaction 1639:cordite factory at 1532:Newcastle upon Tyne 1433:University of Turin 1259:glyceryl trinitrate 727:Detonation velocity 607:Solubility in water 562: g·mol 175:Beilstein Reference 87:Glyceryl trinitrate 28: 5131:Italian inventions 4273:Roussin's red salt 4130:Cyclohexyl nitrite 4021:Nipradilol (K-351) 3720:WebBook page for C 2948:on 1 November 2010 2766:on 15 January 2009 2278: 2146:military engineers 2107:diatomaceous earth 1946:containing excess 1930:—and concentrated 1897: 1609:HM Factory, Gretna 1545:diatomaceous earth 1527:in North America. 1515:company office in 1472: 1468:patent application 1406:sublingual tablets 1363:diatomaceous earth 1227:Infobox references 1134: 26: 5121:Liquid explosives 5086: 5085: 4911: 4902: 4885: 4884: 4818: 4796: 4795: 4716: 4712: 4703: 4699: 4696:N-(1-Iminoethyl)- 4662: 4658: 4649: 4645: 4642:N-(1-Iminoethyl)- 4636: 4632: 4629:N-(1-Iminoethyl)- 4569:2-Iminopiperidine 4525: 4521: 4512: 4508: 4499: 4421: 4150:Isopropyl nitrite 4096:Nitroso compounds 3938: 3923: 3922: 3582:978-0-683-08027-8 3507:(5775): 632–633. 3388:Ogbru, Omudhome. 3350:on 2 October 2018 3305:on 28 August 2021 3240:978-0-471-76865-4 3099:Tallini, Rick F. 3044:Tallini, Rick F. 2923:978-0-471-89980-8 2793:. Springer Nature 2511:"Ascanio Sobrero" 2311:methemoglobinemia 2233:potassium nitrate 2119:civil engineering 1926:, which contains 1914:and concentrated 1889: 1888: 1881: 1863: 1653:contact explosive 1235:Chemical compound 1233: 1232: 1024:Hazard statements 961:Explosive, toxic 933:(Pharmacist only) 928: 707:Shock sensitivity 427:CompTox Dashboard 163:Interactive image 113:-Trinitroglycerin 23:Chemical compound 5143: 5012:dihydropyridines 4912:-arginine (NOHA) 4909: 4900: 4854:alpha aminoacids 4824:chlorogenic acid 4819:-arginine (NOHA) 4816: 4714: 4710: 4701: 4697: 4660: 4656: 4647: 4643: 4634: 4630: 4523: 4519: 4510: 4506: 4497: 4451:3-Chloroindazole 4434: 4433: 4425: 4424: 4415: 4113: 4112: 4050:Nitrofluvastatin 4034: 4033: 3976:Itramin tosilate 3932: 3845: 3844: 3791: 3784: 3777: 3768: 3767: 3755:Dynamite and TNT 3715: 3713: 3711: 3688: 3687: 3685: 3683: 3672:"Nitroglycerine" 3668: 3662: 3661: 3659: 3657: 3643: 3637: 3636: 3600: 3594: 3593: 3591: 3589: 3566: 3560: 3559: 3541: 3535: 3534: 3524: 3492: 3486: 3485: 3483: 3481: 3472:. Archived from 3466: 3460: 3459: 3457: 3455: 3449:www.intramed.net 3441: 3435: 3434: 3404: 3398: 3397: 3385: 3374: 3373: 3366: 3360: 3359: 3357: 3355: 3349: 3343:. Archived from 3330: 3321: 3315: 3314: 3312: 3310: 3301:. Archived from 3290: 3284: 3283: 3265: 3259: 3258: 3252: 3244: 3226: 3220: 3219: 3191: 3185: 3184: 3164: 3158: 3157: 3137: 3131: 3130: 3128: 3126: 3120:webbook.nist.gov 3111: 3105: 3104: 3096: 3087: 3086: 3084: 3082: 3073:. Archived from 3063: 3054: 3053: 3041: 3035: 3034: 3024: 3015: 3009: 3008: 2998: 2989: 2983: 2982: 2980: 2978: 2964: 2958: 2957: 2955: 2953: 2944:. Archived from 2938:"History of TNG" 2934: 2928: 2927: 2909: 2900: 2899: 2897: 2865: 2859: 2856: 2850: 2849: 2832: 2826: 2824: 2823:on 10 July 2006. 2819:. Archived from 2809: 2803: 2802: 2800: 2798: 2782: 2776: 2775: 2773: 2771: 2762:. Archived from 2752: 2746: 2735: 2719: 2713: 2712: 2696: 2690: 2689: 2687: 2685: 2676:. Archived from 2670: 2664: 2663: 2653: 2643: 2611: 2602: 2601: 2599: 2597: 2578: 2572: 2571: 2563: 2557: 2556: 2554: 2552: 2537: 2526: 2525: 2523: 2521: 2515:Oxford Reference 2507: 2501: 2500: 2495:. Archived from 2489: 2483: 2482: 2470: 2464: 2463: 2461: 2459: 2450:. Archived from 2444: 2178:smokeless powder 2101:, particularly " 2067:smokeless powder 2023:nitrogen dioxide 2005:The addition of 1938:, also known as 1884: 1877: 1873: 1870: 1864: 1862: 1821: 1797: 1789: 1753: 1749: 1742: 1734: 1727: 1553: 1448:Emil Oskar Nobel 1326:smokeless powder 1247:trinitroglycerol 1217: 1211: 1208: 1207: 1189: 1185: 1154: 1147: 1140: 1125: 1105: 1101: 1097: 1093: 1089: 1085: 1081: 1077: 1073: 1069: 1055: 1051: 1047: 1043: 1039: 1035: 1031: 1003: 998: 993: 988: 926: 923: 909: 868:Pharmacokinetics 847: 837: 811: 804: 780: 773: 750:Thermochemistry 734: 561: 546: 540: 534: 528: 521:Chemical formula 451: 450: 435: 433: 407: 387: 376: 365: 348: 328: 304:Gmelin Reference 287: 279: 268: 257: 237: 217: 197: 165: 141: 99:Trinitroglycerin 54: 45: 36: 29: 25: 5151: 5150: 5146: 5145: 5144: 5142: 5141: 5140: 5136:Glycerol esters 5091: 5090: 5087: 5082: 5068: 5032:PDE5 inhibitors 4994: 4958: 4945: 4881: 4858: 4792: 4726: 4677: 4545: 4471:7-Nitroindazole 4466:6-Nitroindazole 4461:5-Nitroindazole 4414: 4406: 4183:(thionitrites): 4111: 4108: 4107: 4106: 4070:Propatylnitrate 4032: 4029: 4028: 4027: 3931: 3919: 3834: 3806: 3795: 3735: 3731: 3727: 3723: 3709: 3707: 3699: 3696: 3691: 3681: 3679: 3670: 3669: 3665: 3655: 3653: 3644: 3640: 3601: 3597: 3587: 3585: 3583: 3567: 3563: 3556: 3542: 3538: 3493: 3489: 3479: 3477: 3468: 3467: 3463: 3453: 3451: 3443: 3442: 3438: 3405: 3401: 3386: 3377: 3370:"Nitroglycerin" 3368: 3367: 3363: 3353: 3351: 3347: 3328: 3322: 3318: 3308: 3306: 3299:About.com Money 3291: 3287: 3280: 3266: 3262: 3246: 3245: 3241: 3227: 3223: 3192: 3188: 3166: 3165: 3161: 3139: 3138: 3134: 3124: 3122: 3116:"Nitroglycerin" 3112: 3108: 3097: 3090: 3080: 3078: 3067:"Nitroglycerin" 3065: 3064: 3057: 3042: 3038: 3022: 3016: 3012: 2996: 2990: 2986: 2976: 2974: 2972:www.logwell.com 2966: 2965: 2961: 2951: 2949: 2936: 2935: 2931: 2924: 2910: 2903: 2866: 2862: 2857: 2853: 2834: 2833: 2829: 2811: 2810: 2806: 2796: 2794: 2783: 2779: 2769: 2767: 2754: 2753: 2749: 2720: 2716: 2697: 2693: 2683: 2681: 2672: 2671: 2667: 2612: 2605: 2595: 2593: 2580: 2579: 2575: 2564: 2560: 2550: 2548: 2539: 2538: 2529: 2519: 2517: 2509: 2508: 2504: 2491: 2490: 2486: 2471: 2467: 2457: 2455: 2446: 2445: 2438: 2434: 2429: 2390: 2359:fast heart rate 2338: 2330:William Murrell 2286:angina pectoris 2247: 2241: 2217:naval artillery 2205:petroleum jelly 2142:demolition work 2073: 2053:Main articles: 2051: 1993: 1948:sulfur trioxide 1928:nitrogen oxides 1885: 1874: 1868: 1865: 1828:"Nitroglycerin" 1822: 1820: 1810: 1798: 1787: 1751: 1748: 1744: 1740: 1736: 1733: 1729: 1726: 1722: 1718: 1714: 1710: 1704: 1684:high explosives 1649: 1593: 1574:William Murrell 1551: 1474: 1473: 1425:Ascanio Sobrero 1414: 1386:angina pectoris 1298:Ascanio Sobrero 1290:organic nitrate 1236: 1229: 1224: 1223: 1222:  ?) 1213: 1209: 1205: 1201: 1187: 1183: 1179: 1159: 1158: 1157: 1156: 1149: 1142: 1135: 1131: 1123: 1064: 1026: 1012: 981: 958: 936: 907: 903: 891: 879: 877:Bioavailability 859: 856: 826: 809: 805: 802: 796: 792: 789: 788:Std enthalpy of 778: 774: 771: 765: 761: 758: 757:Std enthalpy of 732: 701:Explosive data 696: 684: 682:Molecular shape 675: 663: 609: 559: 549: 543: 537: 531: 523: 509: 506: 501: 500: 489: 486: 485: 482: 476: 475: 472: 466: 465: 454: 436: 429: 410: 390: 377: 351: 331: 318: 306: 297: 260: 240: 220: 200: 177: 168: 155: 144: 131: 117: 116: 71: 70: 24: 21: 12: 11: 5: 5149: 5139: 5138: 5133: 5128: 5123: 5118: 5113: 5111:Nitrate esters 5108: 5103: 5084: 5083: 5073: 5070: 5069: 5067: 5066: 5056: 5053: 5046: 5039: 5029: 5019: 5002: 4992: 4988: 4973:ACE inhibitors 4966: 4965: 4960: 4956: 4952: 4947: 4943: 4939: 4934: 4929: 4924: 4915: 4914: 4905: 4893: 4891: 4887: 4886: 4883: 4882: 4880: 4879: 4874: 4868: 4866: 4860: 4859: 4857: 4856: 4851: 4846: 4841: 4836: 4831: 4826: 4821: 4812: 4806: 4804: 4798: 4797: 4794: 4793: 4791: 4790: 4785: 4780: 4775: 4770: 4765: 4760: 4755: 4750: 4745: 4740: 4734: 4732: 4728: 4727: 4725: 4724: 4719: 4706: 4693: 4687: 4685: 4679: 4678: 4676: 4675: 4670: 4665: 4652: 4639: 4626: 4621: 4616: 4611: 4606: 4601: 4596: 4591: 4586: 4581: 4576: 4571: 4566: 4561: 4555: 4553: 4547: 4546: 4544: 4543: 4538: 4533: 4528: 4515: 4502: 4493: 4488: 4483: 4478: 4473: 4468: 4463: 4458: 4453: 4448: 4442: 4440: 4431: 4422: 4408: 4407: 4405: 4404: 4399: 4394: 4389: 4384: 4375: 4374: 4369: 4364: 4359: 4344: 4329: 4328: 4323: 4318: 4313: 4308: 4303: 4298: 4293: 4281: 4280: 4275: 4270: 4255: 4254: 4238: 4233: 4228: 4223: 4218: 4213: 4208: 4203: 4198: 4193: 4188: 4176:-Butyl nitrite 4170: 4168:Pentyl nitrite 4165: 4163:-Butyl nitrite 4157: 4155:Methyl nitrite 4152: 4147: 4142: 4137: 4132: 4127: 4120:alkyl nitrites 4109: 4091: 4090: 4085: 4082: 4077: 4072: 4067: 4062: 4057: 4052: 4047: 4042: 4037: 4030: 4023: 4018: 4013: 4008: 4003: 3998: 3993: 3988: 3983: 3978: 3973: 3968: 3963: 3958: 3953: 3941: 3939: 3925: 3924: 3921: 3920: 3918: 3917: 3908: 3907: 3902: 3897: 3892: 3887: 3882: 3877: 3872: 3867: 3862: 3853: 3851: 3842: 3836: 3835: 3833: 3832: 3827: 3822: 3816: 3814: 3808: 3807: 3794: 3793: 3786: 3779: 3771: 3765: 3764: 3752: 3742: 3737: 3733: 3729: 3725: 3721: 3717: 3695: 3694:External links 3692: 3690: 3689: 3663: 3638: 3611:(4): 313–319. 3595: 3581: 3561: 3555:978-0071052399 3554: 3536: 3487: 3476:on 10 May 2017 3461: 3436: 3417:(1): 181–183. 3399: 3375: 3361: 3316: 3293:Bellis, Mary. 3285: 3279:978-0123864543 3278: 3260: 3239: 3221: 3186: 3159: 3132: 3106: 3088: 3055: 3036: 3010: 2984: 2959: 2929: 2922: 2901: 2860: 2851: 2827: 2817:NobelPrize.org 2804: 2777: 2760:NobelPrize.org 2747: 2745: 2744: 2730:. 2nd Series. 2714: 2705:Comptes Rendus 2691: 2680:on 10 May 2017 2665: 2603: 2573: 2566:Haynes, W. M. 2558: 2547:on 16 May 2013 2527: 2502: 2484: 2465: 2454:on 16 May 2013 2435: 2433: 2430: 2428: 2427: 2422: 2417: 2412: 2410:Methyl nitrate 2407: 2402: 2397: 2391: 2389: 2386: 2337: 2334: 2303:blood pressure 2253:(Isordil) and 2243:Main article: 2240: 2237: 2213:nitroguanidine 2197:Frederick Abel 2050: 2047: 2043:compressed air 2009:results in an 1996:nitronium ions 1991: 1887: 1886: 1801: 1799: 1792: 1786: 1783: 1755: 1754: 1746: 1738: 1731: 1724: 1720: 1716: 1712: 1703: 1700: 1696:dinitrotoluene 1648: 1645: 1641:Nobel, Ontario 1613:United Kingdom 1592: 1589: 1578:blood pressure 1563:nitrocellulose 1457: 1456: 1413: 1410: 1322:nitrocellulose 1294:nitro compound 1234: 1231: 1230: 1225: 1203: 1202: 1198:standard state 1195: 1192: 1191: 1180: 1174: 1171: 1170: 1161: 1160: 1150: 1143: 1136: 1121: 1120: 1119: 1118: 1116: 1107: 1106: 1065: 1060: 1057: 1056: 1027: 1022: 1019: 1018: 1013: 1008: 1005: 1004: 982: 977: 974: 973: 963: 962: 959: 956: 953: 952: 943: 942: 938: 937: 935: 934: 920: 918: 912: 911: 904: 899: 896: 895: 892: 887: 884: 883: 880: 875: 872: 871: 864: 863: 860: 857:administration 853: 850: 849: 827: 822: 819: 818: 814: 813: 806: 800: 794: 786: 783: 782: 775: 769: 763: 755: 752: 751: 747: 746: 743: 737: 736: 729: 723: 722: 719: 713: 712: 709: 703: 702: 698: 697: 695: 694: 691: 687: 685: 680: 677: 676: 674: 673: 670: 666: 664: 659: 656: 655: 651: 650: 647: 638: 637: 620: 614: 613: 610: 605: 602: 601: 598: 592: 591: 588: 582: 581: 578: 572: 571: 568: 564: 563: 557: 551: 550: 547: 541: 535: 529: 524: 519: 516: 515: 511: 510: 508: 507: 504: 496: 495: 494: 491: 490: 488: 487: 483: 480: 479: 477: 473: 470: 469: 461: 460: 459: 456: 455: 453: 452: 439: 437: 425: 422: 421: 418: 412: 411: 409: 408: 400: 398: 392: 391: 389: 388: 380: 378: 370: 367: 366: 359: 353: 352: 350: 349: 341: 339: 333: 332: 330: 329: 321: 319: 314: 311: 310: 307: 302: 299: 298: 296: 295: 291: 289: 281: 280: 270: 262: 261: 259: 258: 250: 248: 242: 241: 239: 238: 230: 228: 222: 221: 219: 218: 210: 208: 202: 201: 199: 198: 190: 188: 182: 181: 178: 173: 170: 169: 167: 166: 158: 156: 149: 146: 145: 143: 142: 134: 132: 127: 124: 123: 119: 118: 115: 114: 100: 97: 94: 91: 88: 85: 82: 78: 77: 73: 72: 68: 67: 61: 60: 56: 55: 47: 46: 38: 37: 27:Nitroglycerin 22: 9: 6: 4: 3: 2: 5148: 5137: 5134: 5132: 5129: 5127: 5124: 5122: 5119: 5117: 5114: 5112: 5109: 5107: 5104: 5102: 5099: 5098: 5096: 5089: 5081: 5080: 5077: 5071: 5064: 5060: 5057: 5054: 5051: 5047: 5044: 5040: 5037: 5033: 5030: 5027: 5023: 5020: 5017: 5013: 5009: 5006: 5003: 5000: 4996: 4989: 4986: 4982: 4978: 4974: 4971: 4968: 4967: 4964: 4961: 4959: 4953: 4951: 4948: 4946: 4940: 4938: 4935: 4933: 4930: 4928: 4925: 4923: 4920: 4917: 4916: 4913: 4906: 4904: 4898: 4895: 4894: 4892: 4888: 4878: 4875: 4873: 4872:Calmidazolium 4870: 4869: 4867: 4865: 4861: 4855: 4852: 4850: 4847: 4845: 4842: 4840: 4837: 4835: 4832: 4830: 4827: 4825: 4822: 4820: 4813: 4811: 4808: 4807: 4805: 4803: 4799: 4789: 4786: 4784: 4781: 4779: 4776: 4774: 4771: 4769: 4766: 4764: 4761: 4759: 4756: 4754: 4751: 4749: 4746: 4744: 4741: 4739: 4736: 4735: 4733: 4729: 4723: 4720: 4718: 4707: 4705: 4694: 4692: 4689: 4688: 4686: 4684: 4680: 4674: 4671: 4669: 4666: 4664: 4653: 4651: 4640: 4638: 4627: 4625: 4622: 4620: 4617: 4615: 4612: 4610: 4607: 4605: 4602: 4600: 4597: 4595: 4592: 4590: 4587: 4585: 4582: 4580: 4577: 4575: 4572: 4570: 4567: 4565: 4562: 4560: 4557: 4556: 4554: 4552: 4548: 4542: 4539: 4537: 4534: 4532: 4529: 4527: 4516: 4514: 4503: 4501: 4494: 4492: 4489: 4487: 4484: 4482: 4479: 4477: 4474: 4472: 4469: 4467: 4464: 4462: 4459: 4457: 4454: 4452: 4449: 4447: 4444: 4443: 4441: 4439: 4435: 4432: 4430: 4426: 4423: 4419: 4413: 4409: 4403: 4400: 4398: 4395: 4393: 4390: 4388: 4385: 4383: 4380: 4377: 4376: 4373: 4370: 4368: 4365: 4363: 4360: 4358: 4355: 4353: 4348: 4345: 4343: 4340: 4338: 4334: 4331: 4330: 4327: 4324: 4322: 4319: 4317: 4314: 4312: 4309: 4307: 4304: 4302: 4299: 4297: 4294: 4292: 4289: 4287: 4283: 4282: 4279: 4276: 4274: 4271: 4269: 4266: 4264: 4260: 4257: 4256: 4253: 4250: 4248: 4242: 4239: 4237: 4234: 4232: 4229: 4227: 4224: 4222: 4219: 4217: 4214: 4212: 4209: 4207: 4204: 4202: 4199: 4197: 4194: 4192: 4189: 4187: 4184: 4182: 4177: 4175: 4171: 4169: 4166: 4164: 4162: 4158: 4156: 4153: 4151: 4148: 4146: 4143: 4141: 4140:Hexyl nitrite 4138: 4136: 4135:Ethyl nitrite 4133: 4131: 4128: 4126: 4123: 4121: 4115: 4103: 4101: 4097: 4093: 4092: 4089: 4086: 4083: 4081: 4078: 4076: 4073: 4071: 4068: 4066: 4063: 4061: 4058: 4056: 4053: 4051: 4048: 4046: 4043: 4041: 4038: 4036: 4024: 4022: 4019: 4017: 4014: 4012: 4009: 4007: 4004: 4002: 3999: 3997: 3994: 3992: 3989: 3987: 3984: 3982: 3979: 3977: 3974: 3972: 3969: 3967: 3964: 3962: 3959: 3957: 3954: 3952: 3949: 3947: 3943: 3942: 3940: 3936: 3930: 3926: 3916: 3913: 3910: 3909: 3906: 3903: 3901: 3898: 3896: 3893: 3891: 3888: 3886: 3883: 3881: 3878: 3876: 3873: 3871: 3868: 3866: 3863: 3861: 3858: 3855: 3854: 3852: 3850: 3846: 3843: 3841: 3837: 3831: 3828: 3826: 3823: 3821: 3818: 3817: 3815: 3813: 3809: 3805: 3802: 3799: 3792: 3787: 3785: 3780: 3778: 3773: 3772: 3769: 3762: 3761: 3756: 3753: 3750: 3746: 3743: 3741: 3738: 3736: 3718: 3706: 3702: 3698: 3697: 3677: 3673: 3667: 3651: 3650: 3642: 3634: 3630: 3626: 3622: 3618: 3614: 3610: 3606: 3599: 3584: 3578: 3574: 3573: 3565: 3557: 3551: 3547: 3540: 3532: 3528: 3523: 3518: 3514: 3510: 3506: 3502: 3498: 3491: 3475: 3471: 3465: 3450: 3446: 3440: 3432: 3428: 3424: 3420: 3416: 3412: 3411: 3403: 3395: 3391: 3384: 3382: 3380: 3371: 3365: 3346: 3342: 3338: 3334: 3327: 3320: 3304: 3300: 3296: 3289: 3281: 3275: 3271: 3264: 3256: 3250: 3242: 3236: 3232: 3225: 3217: 3213: 3209: 3205: 3201: 3197: 3190: 3182: 3178: 3174: 3170: 3163: 3155: 3151: 3147: 3143: 3136: 3121: 3117: 3110: 3102: 3095: 3093: 3076: 3072: 3068: 3062: 3060: 3051: 3047: 3040: 3032: 3028: 3021: 3014: 3006: 3002: 2995: 2988: 2973: 2969: 2963: 2947: 2943: 2939: 2933: 2925: 2919: 2915: 2908: 2906: 2896: 2891: 2887: 2883: 2879: 2875: 2871: 2864: 2855: 2847: 2843: 2842: 2837: 2831: 2822: 2818: 2814: 2808: 2792: 2788: 2781: 2765: 2761: 2757: 2751: 2742: 2741:Piroglicerina 2738: 2737: 2733: 2729: 2725: 2718: 2710: 2706: 2702: 2695: 2679: 2675: 2669: 2661: 2657: 2652: 2647: 2642: 2637: 2633: 2629: 2625: 2621: 2617: 2610: 2608: 2591: 2587: 2583: 2577: 2569: 2562: 2546: 2542: 2536: 2534: 2532: 2516: 2512: 2506: 2498: 2494: 2488: 2480: 2476: 2469: 2453: 2449: 2443: 2441: 2436: 2426: 2423: 2421: 2418: 2416: 2413: 2411: 2408: 2406: 2403: 2401: 2398: 2396: 2393: 2392: 2385: 2383: 2379: 2375: 2371: 2367: 2362: 2360: 2356: 2350: 2347: 2343: 2333: 2331: 2327: 2323: 2319: 2314: 2312: 2308: 2304: 2300: 2296: 2291: 2287: 2283: 2274: 2270: 2268: 2264: 2260: 2256: 2252: 2246: 2236: 2234: 2230: 2226: 2222: 2218: 2214: 2208: 2206: 2202: 2198: 2194: 2190: 2186: 2181: 2179: 2173: 2171: 2166: 2162: 2158: 2154: 2149: 2147: 2143: 2139: 2135: 2131: 2128: 2124: 2120: 2116: 2112: 2108: 2104: 2100: 2096: 2092: 2090: 2086: 2082: 2078: 2072: 2068: 2064: 2060: 2056: 2046: 2044: 2040: 2036: 2032: 2028: 2024: 2020: 2016: 2012: 2008: 2003: 2001: 1997: 1989: 1986: 1982: 1979: 1975: 1971: 1968: 1964: 1963:sulfuric acid 1959: 1957: 1953: 1949: 1945: 1944:sulfuric acid 1941: 1937: 1936:sulfuric acid 1933: 1932:sulfuric acid 1929: 1925: 1921: 1917: 1913: 1912:sulfuric acid 1909: 1904: 1902: 1893: 1883: 1880: 1872: 1861: 1858: 1854: 1851: 1847: 1844: 1840: 1837: 1833: 1830: –  1829: 1825: 1824:Find sources: 1818: 1814: 1808: 1807: 1802:This article 1800: 1796: 1791: 1790: 1785:Manufacturing 1782: 1780: 1776: 1771: 1767: 1762: 1760: 1709: 1708: 1707: 1699: 1697: 1693: 1689: 1685: 1680: 1678: 1673: 1672:fulminate cap 1669: 1664: 1662: 1658: 1654: 1644: 1642: 1638: 1634: 1630: 1626: 1622: 1618: 1614: 1610: 1606: 1602: 1598: 1588: 1585: 1584: 1579: 1575: 1571: 1566: 1564: 1559: 1557: 1550: 1546: 1542: 1538: 1533: 1528: 1526: 1522: 1518: 1517:San Francisco 1514: 1510: 1506: 1505:Summit Tunnel 1502: 1498: 1493: 1491: 1487: 1483: 1479: 1469: 1465: 1461: 1455: 1453: 1449: 1445: 1440: 1438: 1437:pyroglycerine 1434: 1430: 1426: 1423: 1419: 1409: 1407: 1403: 1399: 1395: 1391: 1387: 1383: 1379: 1375: 1370: 1368: 1364: 1359: 1353: 1351: 1346: 1342: 1338: 1333: 1331: 1327: 1323: 1319: 1315: 1311: 1307: 1303: 1299: 1295: 1291: 1287: 1283: 1279: 1276: 1272: 1268: 1264: 1260: 1256: 1252: 1248: 1244: 1240: 1239:Nitroglycerin 1228: 1221: 1216: 1199: 1181: 1178:(Permissible) 1177: 1173: 1172: 1168: 1167: 1162: 1155: 1148: 1141: 1117: 1114: 1113: 1109: 1108: 1066: 1063: 1059: 1058: 1028: 1025: 1021: 1020: 1017: 1014: 1011: 1007: 1006: 1002: 997: 992: 987: 983: 980: 976: 975: 971: 969: 964: 960: 955: 954: 950: 949: 944: 939: 932: 922: 921: 919: 917: 914: 913: 905: 902: 898: 897: 893: 890: 886: 885: 881: 878: 874: 873: 869: 865: 861: 858: 852: 851: 846: 841: 836: 831: 828: 825: 821: 820: 817:Pharmacology 815: 807: 799: 791: 785: 784: 776: 768: 760: 754: 753: 748: 744: 742: 739: 738: 730: 728: 725: 724: 720: 718: 715: 714: 710: 708: 705: 704: 699: 692: 689: 688: 686: 683: 679: 678: 671: 668: 667: 665: 662: 658: 657: 652: 648: 646: 645: 640: 639: 636: 632: 628: 624: 621: 619: 616: 615: 611: 608: 604: 603: 599: 597: 596:Boiling point 594: 593: 589: 587: 586:Melting point 584: 583: 579: 577: 574: 573: 569: 566: 565: 558: 556: 553: 552: 525: 522: 518: 517: 512: 503: 502: 499: 492: 478: 468: 467: 464: 457: 449: 445: 444:DTXSID1021407 441: 440: 438: 428: 424: 423: 419: 417: 414: 413: 406: 402: 401: 399: 397: 394: 393: 386: 382: 381: 379: 373: 369: 368: 364: 363:Nitroglycerin 360: 358: 355: 354: 347: 343: 342: 340: 338: 335: 334: 327: 323: 322: 320: 317: 313: 312: 308: 305: 301: 300: 293: 292: 290: 288: 283: 282: 278: 274: 271: 269: 267:ECHA InfoCard 264: 263: 256: 252: 251: 249: 247: 244: 243: 236: 232: 231: 229: 227: 224: 223: 216: 212: 211: 209: 207: 204: 203: 196: 192: 191: 189: 187: 184: 183: 179: 176: 172: 171: 164: 160: 159: 157: 153: 148: 147: 140: 136: 135: 133: 130: 126: 125: 120: 112: 108: 104: 101: 98: 95: 92: 89: 86: 83: 80: 79: 74: 66: 62: 57: 53: 48: 44: 39: 35: 30: 19: 5088: 5075: 5074: 5050:paraxanthine 5026:beta blocker 4969: 4918: 4896: 4700:-ornithine ( 4633:-ornithine ( 4378: 4357:Feprosidnine 4352:Sydnonimines 4350: 4335: 4332: 4284: 4261: 4258: 4247:nitrosamines 4244: 4179: 4173: 4160: 4117: 4094: 3944: 3911: 3890:GSK-2181236A 3856: 3798:Nitric oxide 3758: 3708:. Retrieved 3704: 3680:. Retrieved 3675: 3666: 3654:. Retrieved 3648: 3641: 3608: 3604: 3598: 3586:. Retrieved 3571: 3564: 3545: 3539: 3504: 3500: 3490: 3478:. Retrieved 3474:the original 3464: 3452:. Retrieved 3448: 3439: 3414: 3408: 3402: 3393: 3364: 3352:. Retrieved 3345:the original 3332: 3319: 3307:. Retrieved 3303:the original 3298: 3288: 3269: 3263: 3230: 3224: 3199: 3195: 3189: 3172: 3168: 3162: 3145: 3141: 3135: 3123:. Retrieved 3119: 3109: 3079:. Retrieved 3075:the original 3070: 3049: 3039: 3030: 3026: 3013: 3004: 3000: 2987: 2975:. Retrieved 2971: 2962: 2950:. Retrieved 2946:the original 2941: 2932: 2913: 2877: 2873: 2863: 2854: 2839: 2830: 2821:the original 2816: 2807: 2795:. Retrieved 2790: 2780: 2768:. Retrieved 2764:the original 2759: 2756:"Emil Nobel" 2750: 2740: 2731: 2727: 2717: 2708: 2704: 2694: 2682:. Retrieved 2678:the original 2668: 2623: 2619: 2594:. Retrieved 2585: 2576: 2567: 2561: 2549:. Retrieved 2545:the original 2518:. Retrieved 2514: 2505: 2497:the original 2487: 2468: 2456:. Retrieved 2452:the original 2363: 2355:vasodilation 2351: 2339: 2326:sublingually 2315: 2279: 2259:nitric oxide 2248: 2209: 2182: 2174: 2150: 2144:. Likewise, 2102: 2095:Alfred Nobel 2093: 2074: 2004: 2000:electrophile 1978:nucleophilic 1960: 1905: 1903:(glycerin). 1898: 1875: 1866: 1856: 1849: 1842: 1835: 1823: 1811:Please help 1806:verification 1803: 1779:kilocalories 1763: 1756: 1705: 1681: 1668:desensitized 1665: 1650: 1601:World War II 1594: 1581: 1570:amyl nitrite 1567: 1560: 1548: 1529: 1507:through the 1494: 1475: 1464:Alfred Nobel 1444:Alfred Nobel 1441: 1436: 1418:black powder 1415: 1394:nitric oxide 1376:as a potent 1371: 1354: 1350:nitric oxide 1345:autoignition 1334: 1328:, used as a 1310:construction 1266: 1262: 1258: 1254: 1250: 1246: 1242: 1238: 1237: 1165: 1111: 1015: 967: 957:Main hazards 946: 916:Legal status 797: 766: 643: 580:1.5931 g/cm 122:Identifiers 110: 106: 102: 76:Other names 5063:simvastatin 4897:Precursors: 4834:epicatechin 4758:Indospicine 4713:-arginine ( 4659:-arginine ( 4594:AR-C 102222 4522:-arginine ( 4509:-arginine ( 4372:Sydnonimine 4105:Nitrite (NO 4088:Trolnitrate 4084:Tenitramine 4026:Nitrate (NO 3912:Inhibitors: 3895:Praliciguat 3875:BAY 60-4552 3870:BAY 41-8543 3865:BAY 41-2272 3682:21 November 3394:MedicineNet 3309:10 November 3202:(1): 1–38. 3125:20 February 2977:20 February 2357:produces a 2318:intravenous 2239:Medical use 2201:James Dewar 2019:nitric acid 1983:atoms. The 1970:nitric acid 1956:nitric acid 1916:nitric acid 1869:August 2024 1621:cordite RDB 1597:World War I 1513:Wells Fargo 1378:vasodilator 1374:in medicine 1358:sensitivity 1010:Signal word 951:(OHS/OSH): 567:Appearance 514:Properties 273:100.000.219 195:CHEBI:28787 5095:Categories 5036:sildenafil 5016:nifedipine 4919:Cofactors: 4908:N-Hydroxy- 4815:N-Hydroxy- 4604:Canavanine 4599:BYK-191023 4418:inhibitors 4347:REC15/2739 4326:V-PYRRO/NO 4016:Nicorandil 3905:Vericiguat 3804:modulators 3480:9 November 2874:The Lancet 2734:: 195–201. 2711:: 247–248. 2458:19 October 2432:References 2376:has set a 2185:ballistite 2099:absorbents 2059:Ballistite 1967:protonated 1952:azeotropic 1839:newspapers 1702:Detonation 1625:Royal Navy 1583:The Lancet 1549:Kieselguhr 1497:California 1482:Geesthacht 1454:, Sweden. 1452:Heleneborg 1330:propellant 1314:demolition 1302:explosives 979:Pictograms 889:Metabolism 790:combustion 654:Structure 618:Solubility 555:Molar mass 405:G59M7S0WS3 316:IUPHAR/BPS 226:ChemSpider 150:3D model ( 129:CAS Number 5076:See also: 5022:Nebivolol 4981:captopril 4903:-Arginine 4844:norvaline 4839:ornithine 4753:GW-273629 4709:N-Methyl- 4655:N-Methyl- 4646:-lysine ( 4518:N-Propyl- 4505:N-Methyl- 4486:ARL-17477 4379:Unsorted: 3929:NO donors 3900:Riociguat 3880:BI-703704 3860:Ataciguat 3801:signaling 3749:torpedoes 3249:cite book 2813:"Krümmel" 2770:6 October 2425:RE factor 2346:tolerance 2342:headaches 2299:afterload 2225:wood pulp 2221:gelignite 2189:guncotton 2140:, and in 2138:quarrying 2103:Kieselgur 2071:Gelignite 2015:oxidation 1965:produces 1556:gelignite 1537:Cwm-y-glo 1490:gunpowder 1470:from 1864 1304:, namely 1275:nitrating 1271:explosive 1100:P302+P352 970:labelling 855:Routes of 759:formation 741:RE factor 612:Slightly 416:UN number 294:200-240-8 286:EC Number 215:ChEMBL730 5043:caffeine 5008:blockers 4999:bosentan 4985:losartan 4802:Arginase 4788:VAS-2381 4783:ONO-1714 4731:Unsorted 4491:Indazole 4397:FR146881 4392:FR144220 4382:Cimlanod 4337:Furoxans 4316:PROLI/NO 4286:NONOates 4236:SNO-t-PA 4100:nitrites 4011:NCX-4215 4006:NCX 4040 4001:NCX-4016 3996:NCX-2216 3946:Nitrates 3935:prodrugs 3710:23 March 3656:23 April 3633:12897126 3625:10779131 3588:23 April 3454:14 April 3354:27 March 3081:23 March 2952:14 April 2684:14 April 2660:16103363 2590:Archived 2481:(NIOSH). 2388:See also 2282:medicine 2199:and Sir 2127:railroad 2115:patented 2111:dynamite 2055:Dynamite 2031:glycerin 2027:glycerin 2007:glycerol 1998:are the 1974:glycerol 1908:glycerol 1901:glycerol 1770:brisance 1541:dynamite 1367:dynamite 1306:dynamite 1278:glycerol 1112:NFPA 704 941:Hazards 824:ATC code 246:DrugBank 180:1802063 5061:(e.g., 5059:Statins 5034:(e.g., 5010:(e.g., 4997:(e.g., 4979:(e.g., 4829:ginseng 4778:NXN-462 4773:NCX-456 4763:KD-7040 4743:CKD-712 4476:A-84643 4342:Furoxan 4241:SNO-vWF 3991:NCX-466 3840:Targets 3531:4998847 3522:1798737 3431:3917597 3337:Bibcode 3335:: 151. 2895:5901592 2797:4 March 2651:1189320 2628:Bibcode 2520:16 July 2475:"#0456" 2295:preload 2193:cordite 2130:tunnels 2123:highway 2077:tonnage 2063:Cordite 1853:scholar 1692:acetone 1688:ethanol 1486:Hamburg 1431:at the 1422:chemist 1412:History 1220:what is 1218: ( 1190:mg/m) 882:<1% 842: ( 840:C05AE01 838:) 832: ( 830:C01DA02 812:MJ⋅mol 781:kJ⋅mol 635:alcohol 631:benzene 623:Acetone 576:Density 560:227.085 372:PubChem 309:165859 255:DB00727 139:55-63-0 4890:Others 4849:lysine 4412:Enzyme 4387:FK-409 4301:GLO/NO 4252:SIN-1A 3631:  3623:  3579:  3552:  3529:  3519:  3429:  3276:  3237:  3216:812687 3214:  3050:Analog 2920:  2892:  2658:  2648:  2596:9 July 2551:9 July 2229:sodium 2227:, and 2134:mining 2132:, for 2105:", or 2087:, and 2069:, and 1981:oxygen 1855:  1848:  1841:  1834:  1826:  1633:Dorset 1617:tonnes 1318:mining 1316:, and 1265:), or 1215:verify 1212:  1188:  1186:ppm (2 1184:  1016:Danger 929: 908:  894:Liver 810:  808:−1.529 779:  733:  649:2.154 498:SMILES 346:D00515 206:ChEMBL 59:Names 4922:NADPH 4717:-NMA) 4704:-NIO) 4663:-NMA) 4650:-NIL) 4637:-NIO) 4579:AEITU 4574:1400W 4526:-NPA) 4513:-NMA) 4500:-NIO) 4186:LA810 3812:Forms 3678:. CDC 3629:S2CID 3348:(PDF) 3329:(PDF) 3033:: 71. 3023:(PDF) 3007:: 70. 2997:(PDF) 2320:use, 2267:ALDH2 2165:shale 2163:from 1988:group 1985:nitro 1950:—and 1940:oleum 1860:JSTOR 1846:books 1750:+ 0.5 1743:+ 1.5 1735:+ 2.5 1694:, or 1631:, in 1484:near 1402:ALDH2 1382:heart 1286:ester 1280:with 1255:nitro 1182:C 0.2 1166:NIOSH 745:1.50 731:7,700 721:High 711:High 627:ether 463:InChI 186:ChEBI 152:JSmol 111:alpha 107:alpha 103:alpha 93:Nitro 4937:Heme 4864:CAMK 4683:eNOS 4673:TRIM 4624:MITU 4619:IPTU 4614:EITU 4551:iNOS 4541:TRIM 4438:nNOS 4306:JS-K 4174:tert 3712:2005 3684:2015 3658:2013 3621:PMID 3590:2013 3577:ISBN 3550:ISBN 3527:PMID 3482:2009 3456:2018 3427:PMID 3356:2015 3311:2009 3274:ISBN 3255:link 3235:ISBN 3212:PMID 3127:2024 3083:2005 2979:2024 2954:2018 2918:ISBN 2799:2024 2772:2008 2686:2018 2656:PMID 2598:2024 2553:2024 2522:2024 2460:2016 2159:and 2125:and 2113:and 2039:lead 2035:iron 1961:The 1832:news 1661:PETN 1659:and 1599:and 1388:and 1104:P410 1096:P280 1092:P271 1088:P270 1084:P264 1080:P260 1076:P250 1072:P243 1068:P210 1054:H370 1050:H331 1046:H311 1042:H301 1038:H241 1034:H205 1030:H202 910:min 777:−370 735:m/s 642:log 396:UNII 385:4510 357:MeSH 337:KEGG 326:7053 235:4354 4950:CaM 4932:FMN 4927:FAD 4877:W-7 4810:ABH 4589:AMT 4429:NOS 3915:ODQ 3849:sGC 3757:at 3613:doi 3517:PMC 3509:doi 3419:doi 3204:doi 3177:doi 3150:doi 2890:PMC 2882:doi 2846:PBS 2646:PMC 2636:doi 2624:102 2280:In 2231:or 2170:TNT 2161:gas 2157:oil 2089:HMX 2085:RDX 2081:TNT 2037:or 1976:'s 1815:by 1775:mol 1766:TNT 1759:mol 1728:→ 3 1657:RDX 1619:of 1466:'s 1263:GTN 1253:), 1251:TNG 1176:PEL 968:GHS 845:WHO 835:WHO 801:298 770:298 432:EPA 375:CID 96:TNG 90:GTN 5097:: 5014:: 4991:ET 4983:, 4963:Ca 4942:BH 4349:; 4249:): 4243:; 4178:; 4122:): 4116:; 3703:. 3674:. 3627:. 3619:. 3609:27 3607:. 3525:. 3515:. 3503:. 3499:. 3447:. 3425:. 3415:55 3413:. 3392:. 3378:^ 3331:. 3297:. 3251:}} 3247:{{ 3210:. 3198:. 3173:92 3171:. 3146:64 3144:. 3118:. 3091:^ 3069:. 3058:^ 3048:. 3031:16 3029:. 3025:. 3005:16 3003:. 2999:. 2970:. 2940:. 2904:^ 2888:. 2876:. 2872:. 2844:. 2838:. 2815:. 2789:. 2758:. 2732:10 2709:24 2707:. 2654:. 2644:. 2634:. 2622:. 2618:. 2606:^ 2588:. 2584:. 2530:^ 2513:. 2477:. 2439:^ 2384:. 2313:. 2180:. 2172:. 2083:, 2065:, 2061:, 2057:, 2002:. 1730:CO 1690:, 1663:. 1547:(" 1312:, 1257:, 1243:NG 1102:, 1098:, 1094:, 1090:, 1086:, 1082:, 1078:, 1074:, 1070:, 1052:, 1048:, 1044:, 1040:, 1036:, 1032:, 972:: 931:S3 925:AU 870:: 848:) 793:(Δ 762:(Δ 633:, 629:, 625:, 5065:) 5052:) 5045:) 5038:) 5028:) 5024:( 5018:) 5001:) 4993:B 4987:) 4975:/ 4957:2 4955:O 4944:4 4910:L 4901:L 4817:L 4715:L 4711:L 4702:L 4698:L 4661:L 4657:L 4648:L 4644:L 4635:L 4631:L 4524:L 4520:L 4511:L 4507:L 4498:L 4420:) 4416:( 4354:: 4339:: 4265:: 4161:n 4114:) 4110:2 4102:: 4098:/ 4035:) 4031:3 3948:: 3937:) 3933:( 3790:e 3783:t 3776:v 3734:9 3732:O 3730:3 3728:N 3726:5 3724:H 3722:3 3714:. 3686:. 3660:. 3635:. 3615:: 3592:. 3558:. 3533:. 3511:: 3505:3 3484:. 3458:. 3433:. 3421:: 3396:. 3372:. 3358:. 3339:: 3313:. 3282:. 3257:) 3243:. 3218:. 3206:: 3200:4 3183:. 3179:: 3156:. 3152:: 3129:. 3085:. 2981:. 2956:. 2926:. 2898:. 2884:: 2878:1 2848:. 2825:. 2801:. 2774:. 2688:. 2662:. 2638:: 2630:: 2600:. 2555:. 2524:. 2462:. 2265:( 1992:2 1942:— 1882:) 1876:( 1871:) 1867:( 1857:· 1850:· 1843:· 1836:· 1809:. 1752:O 1747:2 1745:N 1741:O 1739:2 1737:H 1732:2 1725:9 1723:O 1721:3 1719:N 1717:5 1715:H 1713:3 1711:C 1552:" 1400:( 1361:( 1261:( 1249:( 1241:( 1210:Y 1153:4 1146:2 1139:3 927:: 906:3 803:) 798:H 795:c 772:) 767:H 764:f 644:P 548:9 545:O 542:3 539:N 536:5 533:H 530:3 527:C 434:) 430:( 154:) 109:, 105:, 20:.

Index

Nitroglycerin (medication)
Skeletal formula of zwitterionic nitroglycerin
Ball and stick model of nitroglycerin
Spacefill model of nitroglycerin
Preferred IUPAC name
CAS Number
55-63-0
JSmol
Interactive image
Beilstein Reference
ChEBI
CHEBI:28787
ChEMBL
ChEMBL730
ChemSpider
4354
DrugBank
DB00727
ECHA InfoCard
100.000.219
Edit this at Wikidata
EC Number
Gmelin Reference
IUPHAR/BPS
7053
KEGG
D00515
MeSH
Nitroglycerin
PubChem

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