31:
209:
laboratory has isolated and cloned human antibodies to HIV-1 and explored their roles in prevention and therapy. In clinical trials, a broadly neutralizing antibody isolated from an HIV-infected patient was shown to be safe and effective and to interfere with chronic infection in a way that traditional antiretroviral therapy does not. His research has led to the development of innovative vaccines against infectious diseases and new treatments for autoimmunity.
291:
555:
Halper-Stromberg, Ariel; Lu, Ching-Lan; Klein, Florian; Horwitz, Joshua A.; Bournazos, Stylianos; Nogueira, Lilian; Eisenreich, Thomas R.; Liu, Cassie; Gazumyan, Anna; Schaefer, Uwe; Furze, Rebecca C.; Seaman, Michael S.; Prinjha, Rab; Tarakhovsky, Alexander; Ravetch, Jeffrey V.; Nussenzweig, Michel
195:
Nussenzweig received an M.D. from New York
University School of Medicine in 1982 and completed his internship and residency in internal medicine, and a clinical fellowship in infectious diseases at Massachusetts General Hospital in 1985. From 1986 to 1989, he was a postdoctoral fellow in genetics in
208:
Nussenzweig studies molecular aspects of the immune system’s adaptive and innate responses, using a combination of biochemistry, molecular biology, and genetics. Work on adaptive immunity focuses on B lymphocytes and antibodies to HIV-1, while work on innate immunity focuses on dendritic cells. The
499:
Scheid, Johannes F.; Mouquet, Hugo; Feldhahn, Niklas; Seaman, Michael S.; Velinzon, Klara; Pietzsch, John; Ott, Rene G.; Anthony, Robert M.; Zebroski, Henry; Hurley, Arlene; Phogat, Adhuna; Chakrabarti, Bimal; Li, Yuxing; Connors, Mark; Pereyra, Florencia; Walker, Bruce D.; Wardemann, Hedda; Ho,
728:
Schoofs, Till; Klein, Florian; Braunschweig, Malte; Kreider, Edward F.; Feldmann, Anna; Nogueira, Lilian; Oliveira, Thiago; Lorenzi, Julio C. C.; Parrish, Erica H.; Learn, Gerald H.; West, Anthony P.; Bjorkman, Pamela J.; Schlesinger, Sarah J.; Seaman, Michael S.; Czartoski, Julie; McElrath, M.
662:
Lu, Ching-Lan; Murakowski, Dariusz K.; Bournazos, Stylianos; Schoofs, Till; Sarkar, Debolina; Halper-Stromberg, Ariel; Horwitz, Joshua A.; Nogueira, Lilian; Golijanin, Jovana; Gazumyan, Anna; Ravetch, Jeffrey V.; Caskey, Marina; Chakraborty, Arup K.; Nussenzweig, Michel C. (20 May 2016).
200:. Nussenzweig returned to The Rockefeller University as an assistant professor in 1990 and he became an associate professor in 1994, and a professor and senior physician in 1996. In 2013, he was named the first Zanvil A. Cohn and Ralph M. Steinman Professor.
176:
Nussenzweig graduated summa cum laude with a B.A. degree from New York
University College of Arts and Sciences in 1975. He earned a Ph.D. from The Rockefeller University in 1981 in cellular immunology, working in
1140:
188:
As a Ph.D. student, Nussenzweig was the first to show that dendritic cells present foreign antigens to initiate T cell immunity. He also produced the first dendritic cell-specific
1120:
504:; Ravetch, Jeffrey V.; Nussenzweig, Michel C. (2 April 2009). "Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals".
840:
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1032:"With their outstanding research, laureates lay the foundation for understanding the way in which different immunological mechanisms function"
1130:
1150:
977:
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77:
272:
224:
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1053:
558:"Broadly Neutralizing Antibodies and Viral Inducers Decrease Rebound from HIV-1 Latent Reservoirs in Humanized Mice"
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665:"Enhanced clearance of HIV-1–infected cells by broadly neutralizing antibodies against HIV-1 in vivo"
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816:"Twelve Howard Hughes Medical Institute Scientists Elected to American Academy of Arts and Sciences"
1125:
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Juliana; Pfeifer, Nico; Hahn, Beatrice H.; Caskey, Marina; Nussenzweig, Michel C. (20 May 2016).
327:"Contribution of dendritic cells to stimulation of the murine syngeneic mixed leukocyte reaction"
1115:
152:(born February 10, 1955) is a professor and head of the Laboratory of Molecular Immunology at
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731:"HIV-1 therapy with monoclonal antibody 3BNC117 elicits host immune responses against HIV-1"
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607:"HIV-1 antibody 3BNC117 suppresses viral rebound in humans during treatment interruption"
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1004:"The 2016 Rabbi Shai Shacknai Memorial Lecture in Immunology and Cancer Research"
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106:
978:"Toma de Posesión de Académico de Honor del Excmo. Sr. D. Michel C. Nussenzweig"
573:
388:
Proceedings of the
National Academy of Sciences of the United States of America
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30:
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762:
696:
417:
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Nussenzweig, M C; Steinman, R M; Witmer, M D; Gutchinov, B (1 January 1982).
350:
911:[Newly Elected Members of the ABC] (in Portuguese). 16 December 2011
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688:
780:
714:
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342:
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408:
368:
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Rabbi Shai
Shacknai Memorial Prize in Immunology and Cancer Research, 2016
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630:
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123:
1079:"JEM Editorial Board Co-Chair wins 2017 Sanofi-Institut Pasteur Award"
862:"Institute of Medicine Elects 65 New Members, Five Foreign Associates"
381:
887:"Michel C. Nussenzweig elected to National Academy of Sciences"
727:
55:
554:
661:
498:
384:"A monoclonal antibody specific for mouse dendritic cells"
1141:
Members of the United States
National Academy of Sciences
1121:
New York
University College of Arts & Science alumni
1011:
The Hebrew
University of Jerusalem Faculty of Medicine
251:
Nobel Prize
Lecture on behalf of Ralph Steinman, 2011
230:
Lee C. Howley Sr. Prize for
Arthritis Research, 2008
185:
on groundbreaking studies of mouse dendritic cells.
324:
203:
325:Nussenzweig, M. C.; Steinman, R. M. (1 May 1980).
605:Scheid, Johannes F.; et al. (28 July 2016).
1102:
1054:"AAI-BioLegend Herzenberg Award Past Recipients"
192:and cloned the first dendritic cell receptor.
1146:Members of the Brazilian Academy of Sciences
795:"AAI-Thermo Fisher Meritorious Career Award"
450:"Heads of Laboratory: Michel C. Nussenzweig"
160:investigator. He is a member of both the US
1136:Members of the National Academy of Medicine
956:"Prêmio Diáspora Brasil divulga vencedores"
29:
1058:The American Association of Immunologists
770:
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196:the Harvard Medical School laboratory of
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78:New York University School of Medicine
225:American Academy of Arts and Sciences
219:American Association of Immunologists
935:The Official Site of the Nobel Prize
331:The Journal of Experimental Medicine
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1131:Howard Hughes Medical Investigators
278:Sanofi-Institut Pasteur Award, 2017
13:
982:Real Academia Nacional de Farmacia
14:
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275:-BioLegend Herzenberg Award, 2017
1151:21st-century American biologists
1083:Journal of Experimental Medicine
866:News from The National Academies
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204:Summary of research achievements
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479:Howard Hughes Medical Institute
166:US National Academy of Sciences
158:Howard Hughes Medical Institute
1156:Rockefeller University faculty
909:"Eleitos novos membros da ABC"
841:"Past Howley Prize Recipients"
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221:Meritorious Career Award, 2004
1:
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246:Brazilian Academy of Sciences
240:National Academy of Sciences
234:National Academy of Medicine
162:National Academy of Medicine
7:
984:(in Spanish). 11 April 2016
254:Brazil Diaspora Prize, 2015
10:
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574:10.1016/j.cell.2014.07.043
500:David; Wyatt, Richard T.;
454:The Rockefeller University
154:The Rockefeller University
138:The Rockefeller University
70:The Rockefeller University
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475:"Immunity and Tolerance"
755:10.1126/science.aaf0972
689:10.1126/science.aaf1279
343:10.1084/jem.151.5.1196
16:Brazilian immunologist
556:C. (28 August 2014).
409:10.1073/pnas.79.1.161
307:Michel C. Nussenzweig
258:Spanish Royal Academy
150:Michel C. Nussenzweig
23:Michel C. Nussenzweig
931:"Nobel Lecture 2011"
172:Education and career
747:2016Sci...352..997S
681:2016Sci...352.1001L
675:(6288): 1001–1004.
631:10.1038/nature18929
623:2016Natur.535..556S
526:10.1038/nature07930
518:2009Natur.458..636S
400:1982PNAS...79..161N
190:monoclonal antibody
181:’s laboratory with
94:New York University
1085:. 12 December 2017
741:(6288): 997–1001.
617:(7613): 556–560.
512:(7238): 636–640.
267:Robert Koch Award
213:Awards and honors
183:Ralph M. Steinman
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128:Molecular Biology
114:Scientific career
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1087:. Retrieved
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303:profile for
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198:Philip Leder
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134:Institutions
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97:(B.A., 1975)
81:(M.D., 1982)
1111:1955 births
54:São Paulo,
1105:Categories
283:References
124:Immunology
44:1955-02-10
1016:16 August
988:16 August
962:16 August
893:16 August
871:15 August
825:15 August
763:0036-8075
697:0036-8075
418:0027-8424
351:0022-1007
63:Education
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592:25131989
534:19287373
164:and the
1089:5 March
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1038:18 July
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846:18 July
800:14 July
772:5151174
743:Bibcode
735:Science
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619:Bibcode
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514:Bibcode
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396:Bibcode
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360:2185855
299:has an
297:Scholia
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301:author
269:, 2016
260:, 2016
248:, 2011
242:, 2011
236:, 2009
227:, 2007
156:and a
120:Fields
103:Spouse
56:Brazil
1007:(PDF)
538:S2CID
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759:ISSN
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645:PMID
588:PMID
562:Cell
530:PMID
486:2016
461:2016
432:PMID
414:ISSN
365:PMID
347:ISSN
38:Born
767:PMC
751:doi
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685:doi
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635:PMC
627:doi
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