53:
265:
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29:
181:. The cells are porous and have a scavenging function. The LSECs make up around half of the non-parenchymal cells in the liver and are flattened and fenestrated. LSECs have many fenestrae that gives easy communication between the sinusoidal lumen and the
231:
The liver sinusoidal endothelial cells are cultured for a variety of research purposes. The utility of these cells are of particular interest. One problem to overcome is the reversing of
959:
122:
434:
Arii, S; Imamura, M (2000). "Physiological role of sinusoidal endothelial cells and
Kupffer cells and their implication in the pathogenesis of liver injury".
615:
519:
952:
585: โ Histology Learning System at Boston University - "Ultrastructure of the Cell: hepatocytes and sinusoids, sinusoid and space of Disse"
173:
The liver sinusoid has a larger caliber than other types of capillaries and has a lining of specialised endothelial cells known as the
945:
608:
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520:"Maintenance of hepatic sinusoidal endothelial cell phenotype in vitro using organ-specific extracellular matrix scaffolds"
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471:"Role of differentiation of liver sinusoidal endothelial cells in progression and regression of hepatic fibrosis in rats"
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174:
579: โ Histology Learning System at Boston University - "Liver, Gall Bladder, and Pancreas: liver, classic lobule"
219:
Defenestration happens when LSECs are lost rendering the sinusoid as an ordinary capillary. This process precedes
264:
379:"Liver X receptor ฮฑ is essential for the capillarization of liver sinusoidal endothelial cells in liver injury"
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Xie, G; Wang, X; Wang, L; Wang, L; Atkinson, RD; Kanel, GC; Gaarde, WA; Deleve, LD (April 2012).
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known as a sinusoidal capillary, discontinuous capillary or sinusoid, that is similar to a
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DeLeve, LD (November 2007). "Hepatic microvasculature in liver injury".
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Brunt, EM; et al. (June 2014). "Pathology of the liver sinusoids".
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that serves as a location for mixing of the oxygen-rich blood from the
42:
402:
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135:
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38:
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liver with fenestrated endothelial cells. Fenestrae are approx 100
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Sellaro TL, Ravindra AK, Stolz DB, Badylak SF (September 2007).
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93:
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that has made these cells highly specialized phenotypically
28:
968:
517:
34:
1025:
189:, and in the regulation of blood flow in the sinusoids.
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are present in the space of Disse and are involved in
377:
Xing, Y; Zhao, T; Gao, X; Wu, Y (18 February 2016).
967:
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468:
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609:
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436:Journal of Hepato-biliary-pancreatic Surgery
270:A single lobule of the liver of a pig. X 60.
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27:
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204:are separated from the sinusoids by the
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166:and the nutrient-rich blood from the
41:diameter, and the sinusoidal width 5
292:
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13:
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185:. They play a part in filtration,
175:liver sinusoidal endothelial cells
14:
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739:Liver sinusoidal endothelial cell
560:
626:liver, pancreas and biliary tree
263:
251:
16:Hepatic sinusoidal blood vessel
511:
281:
226:
1:
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216:in response to liver damage.
589:Histology at anhb.uwa.edu.au
487:10.1053/j.gastro.2011.12.017
7:
10:
1494:
1290:deep circumflex iliac vein
684:Fibrous capsule of Glisson
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1108:
1099:
1026:To IVC or left renal vein
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758:
749:
632:
583:Histology image: 22103loa
577:Histology image: 15504loa
344:Seminars in Liver Disease
196:foreign material such as
128:
116:
104:
92:
87:
77:
67:
62:
50:
26:
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233:cellular differentiation
768:Intrahepatic bile ducts
158:, having discontinuous
1043:central veins of liver
567:UIUC Histology Subject
210:Hepatic stellate cells
192:The Kupffer cells can
130:Anatomical terminology
82:Central veins of liver
1232:vaginal plexus/vein โ
729:Hepatic stellate cell
536:10.1089/ten.2006.0437
448:10.1007/s005340050152
356:10.1055/s-2007-991515
156:fenestrated capillary
57:Basic liver structure
1376:right gastroepiploic
1079:pampiniform plexus โ
689:Perisinusoidal space
288:SIU SOM Histology GI
258:Human liver sinusoid
1381:pancreaticoduodenal
1368:Superior mesenteric
1346:inferior mesenteric
1336:left gastroepiploic
1285:inferior epigastric
1221:posterior scrotal โ
1207:prostatic plexus โ
800:Common hepatic duct
395:2016NatSR...621309X
194:take up and destroy
72:Hepatic portal vein
1473:Veins of the torso
1116:median sacral vein
795:Right hepatic duct
652:Ligamentum venosum
383:Scientific Reports
111:H3.04.05.0.00014
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1242:internal pudendal
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934:
920:Centroacinar cell
915:Pancreatic islets
853:
852:
833:Sphincter of Oddi
790:Left hepatic duct
481:(4): 918โ927.e6.
403:10.1038/srep21309
313:10.1111/his.12364
245:Additional images
144:
143:
139:
1485:
1319:
1318:
1252:bulb of penis โ
1212:deep of penis โ
1190:uterine plexus โ
1175:inferior gluteal
1168:
1150:superior gluteal
1138:
1131:
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1105:
1033:inferior phrenic
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1022:
995:ascending lumbar
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955:
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889:Uncinate process
828:Ampulla of Vater
823:Common bile duct
778:Canals of Hering
773:Bile canaliculus
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711:Lobules of liver
699:Periportal space
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530:(9): 2301โ2310.
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694:Liver sinusoid
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662:Round ligament
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561:External links
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301:Histopathology
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214:scar formation
206:space of Disse
183:space of Disse
164:hepatic artery
148:liver sinusoid
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1478:Liver anatomy
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751:Biliary tract
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720:Microanatomy
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716:Liver segment
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179:Kupffer cells
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1434:left gastric
1411:appendicular
1396:middle colic
1165:
1135:
1101:Common iliac
1091:common iliac
1074:testicular โ
1047:
783:Interlobular
734:Kupffer cell
706:Portal triad
693:
647:Cantlie line
569:
547:. Retrieved
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98:
1401:right colic
1308:Portal vein
1256:vestibule โ
818:Cystic duct
810:Gallbladder
442:(1): 40โ8.
227:Endothelium
202:Hepatocytes
187:endocytosis
168:portal vein
160:endothelium
88:Identifiers
68:Drains from
1467:Categories
1438:esophageal
1356:left colic
1341:pancreatic
1216:clitoris โ
1145:iliolumbar
1136:posterior:
1055:suprarenal
760:Bile ducts
724:Hepatocyte
524:Tissue Eng
276:References
1406:ileocolic
1185:uterine โ
1180:obturator
1166:anterior:
1070:ovarian โ
1000:subcostal
905:accessory
642:Bare area
389:: 21309.
152:capillary
78:Drains to
1225:labial โ
1109:Unpaired
1017:Systemic
859:Pancreas
677:Quadrate
549:28 April
544:17561801
505:22178212
456:10982590
421:26887957
364:17979075
329:12709169
321:24393125
238:in vitro
221:fibrosis
198:bacteria
1386:jejunal
1323:Splenic
1197:vesical
1065:gonadal
1038:hepatic
973:abdomen
971:of the
672:Caudate
496:3618963
412:4758044
391:Bibcode
63:Details
1429:cystic
1422:Direct
1313:Portal
1086:lumbar
988:system
986:azygos
977:pelvis
896:Ducts
866:Gross
839:Cells
542:
503:
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362:
327:
319:
1391:ileal
1060:renal
969:Veins
634:Liver
325:S2CID
134:[
123:17543
94:Latin
975:and
900:main
885:Head
880:Neck
875:Body
870:Tail
551:2013
540:PMID
501:PMID
452:PMID
417:PMID
360:PMID
317:PMID
1012:IVC
984:To
571:589
532:doi
491:PMC
483:doi
479:142
444:doi
407:PMC
399:doi
352:doi
309:doi
118:FMA
35:rat
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146:A
106:TH
43:ยตm
39:nm
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366:.
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311::
138:]
45:.
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
