69:, becoming tenured chair of several obstetrics and gynecology departments. A member of many professional academic organizations, she has also been and remains president or board member for a collection of reproductive health groups and non-profits. She has been given a number of awards and honorary professorships for her work and public outreach, nationally and internationally.
225:(UCSF) in 2005 to become the Chair of the Department of Obstetrics and Gynecology and Reproductive Sciences. She worked to improve and expand the research done by the department, achieving the top spot at the university for amount of NIH research funding. Recruiting multiple new professors during her tenure, she also worked with
426:
has a measurable correlation with the concentration of the disruptors in pregnant women's urine and the likelihood of miscarriage. Organizing a conference on the subject with other reproductive endocrinologists, fertility organizations, and national politicians, she presented her preliminary findings
94:
mother whose parents were from Italy, Giudice was taught strong values about education from a young age. This focus resulted in her repeatedly skipping grades in both elementary and high school and openly pursuing her interests in math and science, along with many other fields as well. In the middle
431:. She also presented her findings in 2015 at the International Federation of Gynaecology and Obstetrics (FIGO) conference, successfully convincing the delegates attending to release an official FIGO statement calling for global action on the issue.
402:
for endometrial cells and found correlations with expression changes in the already made transcriptome, allowing for greater understanding and treatment of reproductive problems with targeted hormone therapy. Her research into the effects of
427:
and had a discussion on possible impacts. This also led her to create the
Program for Reproductive Health and the Environment (PRHE) at UCSF and a second following conference, whose findings eventually led to the publication of the textbook
422:, Giudice decided to conduct an investigation into the possibility. While the scientific literature had some evidence based on animal studies, no human level research had been conducted at the time. The research she conducted found that
478:
167:
247:
She has advocated for the use of IVF to treat infertility issues and overall suggested that using the process to delay motherhood is an option for women. Relatedly, she was appointed in 2002 as chair of the
1421:
498:
459:
533:
510:
240:
campus. During this time period, she was also made Chair
Emerita of the department and the Robert B. Jaffe, MD, Endowed Professor in the Reproductive Sciences for UCSF. She is also
205:
gynecology clinic. Her work alongside other obstetricians, including Jagdip Powar and Emmet Lamb, increased her interest in conducting reproductive medicine. The final years of her
166:
and specifically the biochemistry of RNA and protein processing, including how proteins undergo translational modification. She continued her work with a second fellowship at the
209:
had her return to
Washington University to mentor under James Warren before finally finishing her training at Stanford as a Reproductive Endocrinology and Infertility Fellow.
471:
398:
due to how the hormonal changes in the menstrual cycle had been previously known to also change the epigenetic markers in related cells. They did a full description of the
482:
463:
501:
gave her the
Fredrick Naftolin Award for Mentorship for the over 250 graduate and undergraduate students she has mentored during her tenure as professor. The
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1416:
372:
306:
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486:
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and ran her own research lab on infertility and reproductive and growth hormones. She spent two decades at
Stanford before transferring to the
1396:
753:
142:. This also resulted in her learning more about reproductive hormones and the biological underpinnings of how genetics shapes reproduction.
442:
Having held membership and leadership positions in multiple professional societies, Giudice also has been on the council for the nonprofit
1456:
544:
Giudice is married to plant biologist Dr
Athanasios "Sakis" Theologis after meeting him during graduate school. They have two children.
848:"Linda Giudice – Stanley McCormick Memorial Professor in the School of Medicine and Professor of Obstetrics & Gynecology, Emeritus"
502:
467:
269:
1411:
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304:
meeting, they decided to write papers separately on different components of what had been found and publish them back-to-back in
222:
197:
internship at
Stanford, she was mentored under then Chair of obstetrics and gynecology at the university, Kent Ueland, and had a
66:
1451:
513:
gave her their
Illumination Award. The 2013 Lifetime Alumni Achievement Award was given to her by the Stanford Medical Center.
318:, helped further explain how IGFs function as a whole and their importance beyond just reproduction, but also in the field of
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131:
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Giudice was furthermore in charge of the 2015 move of the UCSF department from its location at
Parnassus Heights to the new
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Her interests in chemistry and physics led her to pursue a degree in engineering, with an aim of eventually going into
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356:(LIF) upregulation influenced implantation and women with lower levels of the factor had issues with fertility and
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named her the 2008 Women in
Science Award winner. For her research into environmental effects on infertility, the
1441:
1361:
1356:
334:
46:, she had an accelerated education with a heavy emphasis on the sciences, moving through multiple disciplines of
333:
for scientists. Giudice took advantage of this new tool and applied it to identify what genes are up and down
178:
biochemistry and the chemical components that form it in the body. Working alongside well known international
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1223:
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455:
171:
233:'s Undergraduate Research Intern Program. This led to the creation of a summer program at UCSF for interns.
1221:
Cheng, C. Yan (September 2013). "Book Review: Environmental Impacts on Reproductive Health and Fertility".
650:—; DiSaia, Philip J.; Chaudhuri, Gautam; Moore, Thomas R.; Smith, Lloyd H.; Porto, Manuel M. (2012).
451:
285:
281:
249:
360:. These and many others were identified from the microarrays and were used by Giudice to create an entire
58:
and the genetics of women's health, resulting in her returning to her studies to obtain a medical degree.
265:
175:
300:, which was also found simultaneously by a French lab. Presenting what they found jointly at the annual
609:
353:
237:
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110:, however, she found that chemistry was of greater interest to her and changed her major to obtain a
1188:
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1261:"Linda C. Giudice, Johannes L. H. Evers, David L. Healy (eds): Endometriosis: Science and Practice"
1120:
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111:
51:
1302:
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883:
485:'s Committee on Reproductive and Developmental Environmental Health. She is also a fellow of the
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When asked by a patient if her infertility issues might be related to local water pollution with
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151:
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1006:
517:
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155:
127:
55:
748:
186:, which made her want to go to medical school herself to learn more. She then was accepted to
601:
99:, due to her father being transferred in the military and she completed her education there.
91:
579:
Assessing the Medical Risks of Human Oocyte Donation for Stem Cell Research: Workshop Report
419:
380:
206:
115:
8:
855:
749:"Giants in Obstetrics and Gynecology Series: a profile of Linda C. Giudice, MD, PhD, MSc"
497:
Giudice has received numerous awards and accolades for her work throughout her life. The
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107:
103:
62:
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762:
528:. She was also given multiple official lecturer positions, such as by the NIH, the
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43:
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to allow for more factors to be isolated and to potentially find ways to prevent
338:
330:
39:
988:
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896:
766:
554:—; Aplin, John D.; Tabibzadeh, Siamak; Glasser, Stanley R., eds. (2002).
443:
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helped develop a clinical understanding of how progesterone resistance occurs.
384:
168:
Eunice Kennedy Shriver National Institute of Child Health and Human Development
1278:
174:. Her research there had her refocus on what her Ph.D. had been on, involving
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341:. Her lab found that immune system genes had the highest variation, with the
277:
139:
42:, along with the impacts of environmental pollutants on women's fertility. A
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phase. They also discovered insights into infertility, whereby the cytokine
217:
After her medical training was complete, she was accepted at Stanford as an
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784:
404:
357:
163:
27:
23:
1189:"Book Review: Environmental impacts on reproductive health and fertility"
1155:"Book review: Environmental Impacts on Reproductive Health and Fertility"
1121:"Book Review: Environmental Impacts on Reproductive Health and Fertility"
423:
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361:
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47:
31:
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Continuing investigations into the endometrium, Giudice's lab turned to
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In total, she has published over 350 papers in her field of research.
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for Women's Precision Medicine. She is an official member of the US
61:
Afterwards, she has spent her professorship for multiple decades at
652:
Women's Health Review: A Clinical Update in Obstetrics - Gynecology
342:
319:
296:. This discovery required the usage of a cloned protein created by
289:
241:
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Fellows of the American Association for the Advancement of Science
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The Endometrial Factor: A Reproductive Precision Medicine Approach
244:
faculty at Stanford, now as Stanley McCormick Memorial Professor.
273:
599:
345:
311:
293:
170:, where she worked in the Clinical Endocrinology Branch of the
138:
focusing on the biological function and molecular structure of
627:—; Healy, David L.; Evers, Johannes L. H., eds. (2012).
553:
529:
135:
649:
505:
bestowed on her the Distinguished Researcher Award and the
1113:
Environmental Impacts on Reproductive Health and Fertility
606:
Environmental Impacts on Reproductive Health and Fertility
429:
Environmental impacts on reproductive health and fertility
604:; Janssen, Sarah J.; Woodruff, Tracey J., eds. (2010).
524:, along with her being named an honorary fellow of the
810:"Linda C. Giudice, M.D., Ph.D., and Marco Conti, M.D."
516:
Two honorary professorships were gifted to her by the
483:
International Federation of Gynaecology and Obstetrics
464:
Society for Reproductive Endocrinology and Infertility
458:. Previously, she held the president position for the
310:. This finding, alongside her lab's later reveal that
348:
being activated the most to recruit cells during the
252:'s Advisory Committee for Reproductive Health Drugs.
1087:"Linda Giudice honoured as distinguished researcher"
972:"Chemical pollution merits global action: professor"
307:
The Journal of Clinical Endocrinology and Metabolism
150:
Once Giudice was done with her degrees, she began a
577:—; Santa, Eileen; Pool, Robert, eds. (2007).
487:
American Association for the Advancement of Science
325:Then, during the early 1990s, the research company
272:(IGFBP), because of its involvement in the uterine
1298:"Book Review: Endometriosis: Science and Practice"
1266:The Journal of Obstetrics and Gynaecology of India
145:
95:of her attending high school, her family moved to
626:
1338:
576:
526:Royal College of Obstetricians and Gynecologists
391:markers with possible health effects to emerge.
50:for her undergraduate and graduate degrees. Her
479:International Federation of Fertility Societies
944:"BPA's possible role in miscarriages examined"
264:lab meetings, Giudice developed a passion for
30:whose research has focused on the genetics of
754:American Journal of Obstetrics and Gynecology
1392:University of California, Los Angeles alumni
672:
182:had her better understand the importance of
77:
1417:Members of the National Academy of Medicine
911:"Abortion foe is named to FDA health panel"
72:
503:American Society for Reproductive Medicine
468:American Society for Reproductive Medicine
270:insulin-like growth factor-binding protein
130:and then studied under John Pierce at the
1387:Washington University in St. Louis alumni
1315:
1286:
941:
774:
201:in labor and delivery and another in the
1152:
969:
942:Marchione, Marilynn (October 14, 2013).
536:'s Founders Oration position and medal.
1258:
1007:"An interview with Dr Linda C. Giudice"
742:
740:
738:
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734:
732:
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223:University of California, San Francisco
158:in the lab of later Nobel Prize winner
67:University of California, San Francisco
1372:21st-century American women scientists
1367:20th-century American women scientists
1339:
1118:
1055:
1053:
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1049:
881:[Option to delay motherhood].
803:
801:
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16:American gynecologist and obstetrician
1220:
1186:
1004:
876:
673:—; Simon, Carlos, eds. (2017).
499:Society of Reproductive Investigation
460:Society for Gynecologic Investigation
288:are increased due to the action of a
132:University of California, Los Angeles
1397:National Institutes of Health people
1295:
1061:"Linda Giudice honoured by the RCOG"
1000:
998:
970:Fayerman, Pamela (October 7, 2015).
879:"Opcion para retrasar la maternidad"
807:
507:American Medical Women's Association
1253:Endometriosis: Science and Practice
1046:
798:
703:
629:Endometriosis: Science and Practice
322:'s research on cancer development.
13:
1457:American people of Italian descent
1160:BMJ Sexual and Reproductive Health
534:Royal Reproductive Biology Society
532:Sadler lecturer position, and the
481:and holds a chair position in the
231:University of California, Berkeley
120:Washington University in St. Louis
14:
1468:
1119:Buster, John E. (December 2010).
995:
814:Seminars in Reproductive Medicine
411:and their impact on the onset of
1317:10.1016/j.fertnstert.2013.05.003
1139:10.1016/j.fertnstert.2010.09.003
539:
511:American Infertility Association
477:Giudice is the president of the
437:
371:. This also led them, alongside
1412:UCSF School of Medicine faculty
1245:
1105:
1079:
1005:Nowak, Romana A. (April 2018).
877:Arias, Fanny D. (May 6, 2015).
747:Romero, Roberto (August 2021).
547:
146:Expanding her medical interests
86:to an immigrant family, with a
1437:American women medical writers
963:
935:
903:
870:
840:
1:
1452:Rockefeller University people
1296:Batt, Ronald E. (July 2013).
1224:Perspectives in Public Health
696:
456:National Academy of Inventors
280:of pregnant women found that
1207:10.3109/14647273.2010.482819
452:National Academy of Medicine
375:, to determine that certain
250:Food and Drug Administration
106:. After starting classes at
38:, and the mechanisms of the
7:
1407:Stanford University faculty
1259:Fainaru, Ofer (June 2014).
472:World Endometriosis Society
266:insulin-like growth factors
255:
176:thyroid-stimulating hormone
162:. Her work centered around
10:
1473:
1402:Stanford University alumni
1382:Columbia University alumni
767:10.1016/j.ajog.2021.04.230
610:Cambridge University Press
354:leukemia inhibitory factor
118:. Continuing with this at
1447:American textbook writers
1279:10.1007/s13224-014-0565-9
1153:Stephens, Imogen (2011).
492:
212:
78:Chemistry and engineering
1432:American medical writers
1427:Medical textbook writers
1237:10.1177/1757913913499993
1173:10.1136/jfprhc.2010.0012
656:Elsevier Health Sciences
583:National Academies Press
314:protease comes from the
276:. Her lab's work on the
268:(IGFs) and particularly
73:Early life and education
52:postdoctoral fellowships
1303:Fertility and Sterility
1126:Fertility and Sterility
1012:Biology of Reproduction
808:Carr, Bruce R. (2009).
329:was created to produce
262:pediatric endocrinology
152:postdoctoral fellowship
1442:Women textbook writers
1362:American obstetricians
1357:American gynecologists
827:10.1055/s-0028-1108003
518:University of Florence
184:translational medicine
156:Rockefeller University
128:biomedical engineering
56:translational medicine
1187:Moore, Harry (2010).
1025:10.1093/biolre/ioy022
260:Due to attending the
112:Bachelor's of Science
1377:People from Brooklyn
1352:Women gynaecologists
420:endocrine disruptors
381:intrauterine devices
190:'s medical program.
116:chemical engineering
919:. December 26, 2002
856:Stanford University
602:Guillette, Louis J.
377:oral contraceptives
219:assistant professor
188:Stanford University
108:Columbia University
104:nuclear engineering
63:Stanford University
1093:. November 9, 2008
448:steering committee
446:and on the UCSF's
373:Karen Smith-McCune
84:Brooklyn, New York
54:introduced her to
1091:Endometriosis.org
1065:Endometriosis.org
977:The Vancouver Sun
522:Aarhus University
302:Endocrine Society
227:Kaiser Permanente
195:internal medicine
122:, she received a
97:Norfolk, Virginia
92:second generation
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858:. March 14, 2014
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180:endocrinologists
20:Linda C. Giudice
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1067:. June 23, 2016
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681:. p. 284.
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658:. p. 496.
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635:. p. 600.
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612:. p. 250.
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585:. p. 112.
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562:. p. 696.
556:The Endometrium
550:
542:
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407:on endometrial
389:proinflammatory
339:menstrual cycle
331:DNA microarrays
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124:Master's degree
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40:menstrual cycle
22:is an American
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989:Newspapers.com
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897:Newspapers.com
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