Knowledge

Comins' reagent

Source 📝

428: 240: 147: 33: 24: 570: 104: 493:
Comins, Daniel L.; Dehghani, Ali (1992). "Pyridine-Derived Triflating Reagents: An Improved Preparation of Vinyl Triflates from Metallo Enolates".
611: 289: 650: 427: 630: 448: 604: 645: 477: 254: 400: 655: 23: 597: 435:
It was first reported in 1992 by Daniel Comins. The vinyl triflates prepared are useful as substrates in the
197: 142: 218: 421: 154: 541: 235: 635: 417: 536: 524: 640: 124: 80: 585: 206: 45: 8: 263:
InChI=1S/C7H3ClF6N2O4S2/c8-4-1-2-5(15-3-4)16(21(17,18)6(9,10)11)22(19,20)7(12,13)14/h1-3H
239: 146: 70: 273:
InChI=1/C7H3ClF6N2O4S2/c8-4-1-2-5(15-3-4)16(21(17,18)6(9,10)11)22(19,20)7(12,13)14/h1-3H
506: 473: 577: 546: 502: 312: 186: 527:(1995). "Palladium-Catalyzed Cross-Coupling Reactions of Organoboron Compounds". 436: 581: 394: 624: 520: 382: 135: 32: 550: 468:
Mundy, Bradford P.; Ellerd, Michael G.; Favaloro, Frank G. Jr. (2005).
361: 155: 115: 393:
Except where otherwise noted, data are given for materials in their
569: 103: 173: 93: 223: 424:
from the corresponding ketone enolates or dienolates.
467: 420:-donating reagent that is used to synthesize vinyl 297:O=S(=O)(N(c1ccc(Cl)cn1)S(=O)(=O)C(F)(F)F)C(F)(F)F 622: 470:Name Reactions and Reagents in Organic Synthesis 185: 79: 492: 605: 519: 612: 598: 238: 145: 123: 540: 205: 234: 623: 136: 387:45 °C (113 °F; 318 K) 266:Key: TUFGVZMNGTYAQD-UHFFFAOYSA-N 564: 449:Bis(trifluoromethanesulfonyl)aniline 431:Sample Reaction With Comin's Reagent 57:-(methanesulfonyl)methanesulfonamide 276:Key: TUFGVZMNGTYAQD-UHFFFAOYAK 176: 13: 651:Substances discovered in the 1990s 426: 14: 667: 568: 339: 333: 330: 324: 31: 22: 397:(at 25 °C , 100 kPa). 631:Reagents for organic chemistry 513: 486: 461: 351: 345: 318: 1: 507:10.1016/S0040-4039(00)60957-7 454: 584:. You can help Knowledge by 7: 442: 10: 672: 563: 646:Trifluoromethyl compounds 391: 305: 285: 250: 63: 44: 39: 30: 21: 53:-(5-Chloropyridin-2-yl)- 656:Organic compound stubs 576:This article about an 432: 430: 46:Preferred IUPAC name 551:10.1021/cr00039a007 495:Tetrahedron Letters 369: g·mol 18: 433: 401:Infobox references 16: 593: 592: 501:(42): 6299–6302. 409:Chemical compound 407: 406: 219:CompTox Dashboard 105:Interactive image 663: 614: 607: 600: 578:organic compound 572: 565: 555: 554: 544: 535:(7): 2457–2483. 529:Chemical Reviews 517: 511: 510: 490: 484: 483: 472:(2nd ed.). 465: 368: 353: 347: 341: 335: 332: 326: 320: 313:Chemical formula 243: 242: 227: 225: 209: 189: 178: 157: 149: 138: 127: 107: 83: 35: 26: 19: 17:Comins' Reagent 15: 671: 670: 666: 665: 664: 662: 661: 660: 636:Chloropyridines 621: 620: 619: 618: 561: 559: 558: 542:10.1.1.735.7660 518: 514: 491: 487: 480: 466: 462: 457: 445: 437:Suzuki reaction 414:Comins' reagent 410: 403: 398: 366: 356: 350: 344: 338: 329: 323: 315: 301: 298: 293: 292: 281: 278: 277: 274: 268: 267: 264: 258: 257: 246: 228: 221: 212: 192: 179: 167: 130: 110: 97: 86: 73: 59: 58: 12: 11: 5: 669: 659: 658: 653: 648: 643: 638: 633: 617: 616: 609: 602: 594: 591: 590: 573: 557: 556: 521:Miyaura, Norio 512: 485: 479:978-0471228547 478: 459: 458: 456: 453: 452: 451: 444: 441: 408: 405: 404: 399: 395:standard state 392: 389: 388: 385: 379: 378: 375: 371: 370: 364: 358: 357: 354: 348: 342: 336: 327: 321: 316: 311: 308: 307: 303: 302: 300: 299: 296: 288: 287: 286: 283: 282: 280: 279: 275: 272: 271: 269: 265: 262: 261: 253: 252: 251: 248: 247: 245: 244: 236:DTXSID40327763 231: 229: 217: 214: 213: 211: 210: 202: 200: 194: 193: 191: 190: 182: 180: 172: 169: 168: 166: 165: 161: 159: 151: 150: 140: 132: 131: 129: 128: 120: 118: 112: 111: 109: 108: 100: 98: 91: 88: 87: 85: 84: 76: 74: 69: 66: 65: 61: 60: 49: 48: 42: 41: 37: 36: 28: 27: 9: 6: 4: 3: 2: 668: 657: 654: 652: 649: 647: 644: 642: 639: 637: 634: 632: 629: 628: 626: 615: 610: 608: 603: 601: 596: 595: 589: 587: 583: 579: 574: 571: 567: 566: 562: 552: 548: 543: 538: 534: 530: 526: 525:Suzuki, Akira 522: 516: 508: 504: 500: 496: 489: 481: 475: 471: 464: 460: 450: 447: 446: 440: 438: 429: 425: 423: 419: 415: 402: 396: 390: 386: 384: 383:Melting point 381: 380: 376: 373: 372: 365: 363: 360: 359: 317: 314: 310: 309: 304: 295: 294: 291: 284: 270: 260: 259: 256: 249: 241: 237: 233: 232: 230: 220: 216: 215: 208: 204: 203: 201: 199: 196: 195: 188: 184: 183: 181: 175: 171: 170: 163: 162: 160: 158: 153: 152: 148: 144: 141: 139: 137:ECHA InfoCard 134: 133: 126: 122: 121: 119: 117: 114: 113: 106: 102: 101: 99: 95: 90: 89: 82: 78: 77: 75: 72: 68: 67: 62: 56: 52: 47: 43: 38: 34: 29: 25: 20: 641:Sulfonamides 586:expanding it 575: 560: 532: 528: 515: 498: 494: 488: 469: 463: 434: 413: 411: 377:White solid 64:Identifiers 54: 50: 374:Appearance 306:Properties 143:100.157.321 81:145100-51-2 625:Categories 455:References 362:Molar mass 207:WS933U9U66 116:ChemSpider 92:3D model ( 71:CAS Number 537:CiteSeerX 422:triflates 164:629-110-2 156:EC Number 443:See also 418:triflyl 174:PubChem 539:  476:  367:392.67 290:SMILES 187:388544 125:344376 40:Names 580:is a 416:is a 255:InChI 94:JSmol 582:stub 474:ISBN 412:The 198:UNII 547:doi 503:doi 224:EPA 177:CID 627:: 545:. 533:95 531:. 523:; 499:33 497:. 439:. 331:Cl 613:e 606:t 599:v 588:. 553:. 549:: 509:. 505:: 482:. 355:2 352:S 349:4 346:O 343:2 340:N 337:6 334:F 328:3 325:H 322:7 319:C 226:) 222:( 96:) 55:N 51:N

Index

Skeletal formula of Comin's Reagent

Preferred IUPAC name
CAS Number
145100-51-2
JSmol
Interactive image
ChemSpider
344376
ECHA InfoCard
100.157.321
Edit this at Wikidata
EC Number
PubChem
388544
UNII
WS933U9U66
CompTox Dashboard
DTXSID40327763
Edit this at Wikidata
InChI
SMILES
Chemical formula
Molar mass
Melting point
standard state
Infobox references
triflyl
triflates
Sample Reaction With Comin's Reagent

Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.