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Cholesteryl ester

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20: 310:"Illawarra Health and Medical Research Institute Researchers Report on Findings in Huntington Disease (Cholesteryl ester levels are elevated in the caudate and putamen of Huntington's disease patients) (Cholesteryl ester levels are elevated in ...)." 128:(CETP). The decrease in cholesteryl ester can lower HDL and increase LDL, which may be an indicator of cardiovascular problems, as indicated by intervention studies. Increasing HDL values has the potential to prevent mortality associated with 384:"Cholesteryl ester transfer protein: at the heart of the action of lipid-modulating therapy with statins, fibrates, niacin, and cholesteryl ester transfer protein inhibitors" 331:
Liu, Shenping; Mistry, Anil; Reynolds, Jennifer M.; Lloyd, David B.; Griffor, Matthew C.; Perry, David A.; Ruggeri, Roger B.; Clark, Ronald W.; Qiu, Xiayang (October 2012).
66: 96:, of people with Huntington disease compared with levels in controls. Increase in cholesteryl ester has also been found in other neurological disorders like 65:. Esters are formed by replacing at least one –OH (hydroxyl) group with an –O–alkyl (alkoxy) group. They are hydrolyzed by pancreatic enzymes, such as 244:
Phillips, Gabrielle R.; Hancock, Sarah E.; Brown, Simon H. J.; Jenner, Andrew M.; Kreilaus, Fabian; Newell, Kelly A.; Mitchell, Todd W. (2020-11-20).
211: 166: 160: 155: 145: 195: 150: 121: 318:, link.gale.com/apps/doc/A643924682/AONE?u=cuny_hunter&sid=AONE&xid=6782d457. Accessed 2 May 2021. 436: 80:. Increased levels of cholesteryl ester have been found in certain parts of the brain of people with 246:"Cholesteryl ester levels are elevated in the caudate and putamen of Huntington's disease patients" 228: 113: 117: 81: 101: 38: 224: 62: 257: 8: 129: 261: 408: 383: 359: 332: 288: 245: 205: 97: 76:
Cholesteryl ester is found in human brains as lipid droplets which store and transport
441: 413: 364: 333:"Crystal Structures of Cholesteryl Ester Transfer Protein in Complex with Inhibitors" 293: 275: 191: 403: 395: 354: 344: 283: 265: 133: 85: 70: 399: 270: 430: 279: 61:. Cholesteryl esters have a lower solubility in water due to their increased 349: 417: 368: 297: 77: 58: 46: 42: 69:, to produce cholesterol and free fatty acids. They are associated with 382:
Chapman, M. J.; Le Goff, W.; Guerin, M.; Kontush, A. (2 January 2010).
93: 50: 19: 84:. Higher concentrations of cholesteryl ester have been found in the 54: 190:(5th ed.). Philadelphia: Wolters Kluwer Health. p. 175. 89: 35: 31: 23:
Cholesterol oleate, a member of the cholesteryl ester family
381: 125: 243: 330: 428: 107: 188:Lippincott's illustrated reviews, biochemistry 186:Ferrier, Richard A. Harvey, Denise R. (2011). 210:: CS1 maint: multiple names: authors list ( 407: 358: 348: 287: 269: 227:at the U.S. National Library of Medicine 18: 185: 45:. The ester bond is formed between the 429: 112:Cholesteryl ester is transported from 326: 324: 312:Obesity, Fitness & Wellness Week 239: 237: 167:Lecithin–cholesterol acyltransferase 161:Acyl CoA cholesteryl acyltransferase 156:Cholesterol esterification disorder 13: 146:Cholesteryl ester transfer protein 126:cholesteryl ester transfer protein 14: 453: 321: 234: 151:Cholesteryl ester storage disease 337:Journal of Biological Chemistry 375: 304: 218: 179: 1: 173: 122:very low-density lipoproteins 108:Transfer of cholesteryl ester 7: 139: 10: 458: 271:10.1038/s41598-020-76973-8 114:high-density lipoproteins 400:10.1093/eurheartj/ehp399 229:Medical Subject Headings 118:low-density lipoproteins 350:10.1074/jbc.M112.380063 16:An ester of cholesterol 388:European Heart Journal 30:are a type of dietary 24: 316:Gale Academic OneFile 22: 130:cardiovascular risks 82:Huntington's disease 67:cholesterol esterase 343:(44): 37321–37329. 262:2020NatSR..1020314P 102:Alzheimer's disease 437:Carboxylate esters 250:Scientific Reports 225:Cholesterol+Esters 98:multiple sclerosis 28:Cholesteryl esters 25: 314:, 2020, p. 2684. 449: 422: 421: 411: 379: 373: 372: 362: 352: 328: 319: 308: 302: 301: 291: 273: 241: 232: 222: 216: 215: 209: 201: 183: 457: 456: 452: 451: 450: 448: 447: 446: 427: 426: 425: 380: 376: 329: 322: 309: 305: 242: 235: 223: 219: 203: 202: 198: 184: 180: 176: 142: 134:atherosclerosis 110: 71:atherosclerosis 17: 12: 11: 5: 455: 445: 444: 439: 424: 423: 394:(2): 149–164. 374: 320: 303: 233: 217: 196: 177: 175: 172: 171: 170: 164: 158: 153: 148: 141: 138: 109: 106: 92:, but not the 63:hydrophobicity 15: 9: 6: 4: 3: 2: 454: 443: 440: 438: 435: 434: 432: 419: 415: 410: 405: 401: 397: 393: 389: 385: 378: 370: 366: 361: 356: 351: 346: 342: 338: 334: 327: 325: 317: 313: 307: 299: 295: 290: 285: 281: 277: 272: 267: 263: 259: 255: 251: 247: 240: 238: 230: 226: 221: 213: 207: 199: 197:9781608314126 193: 189: 182: 178: 168: 165: 162: 159: 157: 154: 152: 149: 147: 144: 143: 137: 135: 131: 127: 124:(VLDLs) with 123: 119: 115: 105: 103: 99: 95: 91: 87: 83: 79: 74: 72: 68: 64: 60: 56: 52: 48: 44: 40: 37: 33: 29: 21: 391: 387: 377: 340: 336: 315: 311: 306: 256:(1): 20314. 253: 249: 220: 187: 181: 111: 75: 27: 26: 120:(LDLs) and 78:cholesterol 59:cholesterol 49:group of a 47:carboxylate 43:cholesterol 39:derivatives 431:Categories 174:References 116:(HDLs) to 94:cerebellum 51:fatty acid 280:2045-2322 206:cite book 57:group of 442:Steroids 418:19825813 369:22961980 298:33219259 140:See also 132:such as 55:hydroxyl 53:and the 34:and are 409:2806550 360:3481329 289:7680097 258:Bibcode 90:putamen 86:caudate 416:  406:  367:  357:  296:  286:  278:  231:(MeSH) 194:  169:(LCAT) 163:(ACAT) 36:ester 32:lipid 414:PMID 365:PMID 294:PMID 276:ISSN 212:link 192:ISBN 100:and 88:and 404:PMC 396:doi 355:PMC 345:doi 341:287 284:PMC 266:doi 41:of 433:: 412:. 402:. 392:31 390:. 386:. 363:. 353:. 339:. 335:. 323:^ 292:. 282:. 274:. 264:. 254:10 252:. 248:. 236:^ 208:}} 204:{{ 136:. 104:. 73:. 420:. 398:: 371:. 347:: 300:. 268:: 260:: 214:) 200:.

Index


lipid
ester
derivatives
cholesterol
carboxylate
fatty acid
hydroxyl
cholesterol
hydrophobicity
cholesterol esterase
atherosclerosis
cholesterol
Huntington's disease
caudate
putamen
cerebellum
multiple sclerosis
Alzheimer's disease
high-density lipoproteins
low-density lipoproteins
very low-density lipoproteins
cholesteryl ester transfer protein
cardiovascular risks
atherosclerosis
Cholesteryl ester transfer protein
Cholesteryl ester storage disease
Cholesterol esterification disorder
Acyl CoA cholesteryl acyltransferase
Lecithin–cholesterol acyltransferase

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