Knowledge

Bufotoxin

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Symptoms may vary depending on certain factors such as the size and age of the victim. Other than the first, more benign symptoms (such as a tingling or burning sensation in the eyes, mucous membranes, or in exposed wounds), the most frequently described symptoms in the medical literature are :
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Poisoning from toad toxin is rare but can kill. It can occur when someone drinks toad soup, eats toad meat or toad eggs, or swallows live toads on a bet. It can also happen when someone deliberately takes commercial substances made with toad toxins. These go under names including "Kyushin", "Chan
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One epileptic episode caused by Bufotoxins was observed in a 5-year old child, minutes after they had placed a Bufo alvarius in their mouth. The child was successfully treated with diazepam and phenobarbital.
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In extreme cases following ingestion of mucus or skin of the toad, death generally occurs within 6 and 24 hours. Victims surviving past 24 hours generally will recover.
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Chemical structure of one of the main components of bufotoxin, a conjugate of bufagin with suberylarginine. This component is itself sometimes called bufotoxin.
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Do not translate text that appears unreliable or low-quality. If possible, verify the text with references provided in the foreign-language article.
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Kißmer, B.; Wichtl, M. (1986). "Bufadienolide aus Samen von Helleborus odorus" [Bufadienolides from the Seeds of Helleborus odorus].
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family) and other amphibians, and in some plants and mushrooms. The exact composition varies greatly with the specific source of the toxin.
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Siperstein MD, Murray AW, Titus E (March 1957). "Biosynthesis of cardiotonic sterols from cholesterol in the toad, Bufo marinus".
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Su" (marketed as a painkiller, topical anesthetic or cardiac treatment), "Rockhard" and "Love Stone" (marketed as aphrodisiacs).
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purposes by some individuals. However, the practice of using these substances derived from animals for spiritual experiences or
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Despite being a frequent target for milking, these toads still carry cardio toxic bufotoxins which have been linked to deaths.
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of caught, washed toads for a white venom and drying; the final dried poison is usually brown, with a chunk or flake form.
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Content in this edit is translated from the existing French Knowledge article at ]; see its history for attribution.
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Toxic and Hallucinogenic Mushroom Poisoning: A Handbook for Physicians and Mushroom Hunters
501:"Chan Su" (literally "toad venom") is often adulterated with standard painkillers, such as 282: 1050: 8: 2414: 550: 544: 377: 323: 244:
The toxic substances found in toads can be divided by chemical structure in two groups:
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note: some toxins are produced by lower species and pass through intermediate species
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Chen KK, Kovaríková A (December 1967). "Pharmacology and toxicology of toad venom".
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Trakulsrichai, S; Chumvanichaya, K; Sriapha, C; Tongpoo, A; Wananukul, W (2020).
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Hitt M, Ettinger DD. Toad toxicity. N Engl J Med ; 1986 ; 314:1517
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to the source of your translation. A model attribution edit summary is
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The effects of the bufotoxins in these toads are not well understood.
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concerns about the potential suffering inflicted on the animal.
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combined by weight. The extract is obtained by squeezing the
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Kuo, HY; Hsu, CW; Chen, JH; Wu, YL; Shen, YS (March 2007).
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to this template: there are already 1,482 articles in the
2058: 983:"Toad Poisoning: Clinical Characteristics and Outcomes" 447:, is often found in certain Chinese folk remedies. The 439:
Extract from the skin of certain Asian toads, such as
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New York: Van Nostrand Reinhold. 304:Toads known to secrete bufotoxins. 24: 1358:Staphylococcal Enterotoxin B (SEB) 908:Cartwright, Megan (29 June 2015). 744:Journal of Pharmaceutical Sciences 513:. It may be ingested or injected. 492: 25: 2457: 1038: 795:. Berlin: Springer Berlin. 2013. 2410: 2409: 34: 1442:Extracellular adenylate cyclase 1025: 952:10.1016/j.forsciint.2009.02.006 233:to describe the conjugate of a 940:Forensic Science International 809: 735: 700: 671: 636: 465: 456: 391: 176: 121:You may also add the template 13: 1: 1594:Fibronectin binding protein A 629: 434: 657:10.1016/0003-9861(57)90254-0 123:{{Translated|fr|Bufotoxine}} 7: 1335:Staphylococcus aureus alpha 1313:Panton–Valentine leukocidin 269:-related substances (e.g., 165:, skin, and poison of many 93:will aid in categorization. 27:Class of chemical compounds 10: 2462: 1353:Toxic shock syndrome toxin 858:Emergency Medicine Journal 297: 293: 68:Machine translation, like 2405: 2392: 2330: 2250:(+)-Allopumiliotoxin 267A 2237: 2211: 2200: 2155: 2097: 1991: 1980: 1749: 1606: 1577: 1513: 1450: 1397: 1370: 1323: 1298: 1289: 1262: 1175: 1166: 1146: 1135: 583:(starting at extremities) 357:Melanophryniscus moreirae 308:Toads frequently "milked" 300:List of poisonous animals 49:the corresponding article 1643:beta-Nitropropionic acid 517:Symptoms of Intoxication 273:), are sought after for 1427:Heat-labile enterotoxin 1418:heat-stable enterotoxin 870:10.1136/emj.2006.044602 189:Bufotoxins can contain 132:For more guidance, see 1536:Bacillus thuringiensis 756:10.1002/jps.2600561202 474: 186: 150:are a family of toxic 1047:, californiaherps.com 721:10.1055/s-2007-969103 607:loss of consciousness 441:Bufo bufo gargarizans 350:Nannophryne variegata 184: 134:Knowledge:Translation 105:copyright attribution 1437:Pseudomonas exotoxin 1000:10.2147/TCRM.S272863 283:responsible drug use 551:bundle branch block 545:atrial fibrillation 402:Anaxyrus americanus 2353:Alpha-Bungarotoxin 1523:Lipopolysaccharide 1481:Pore-forming toxin 838:蟾酥 bufonis venenum 612:respiratory arrest 602:anaphylactic shock 537:cardiac arrhythmia 445:Bufo melanostictus 416:Bufo melanostictus 253:cardiac glycosides 187: 113:interlanguage link 2436:Alpha-Amino acids 2423: 2422: 2388: 2387: 2358:Beta-Bungarotoxin 2302:Pumiliotoxin 251D 2196: 2195: 1602: 1601: 1589:Clumping factor A 1509: 1508: 1393: 1392: 1366: 1365: 1285: 1284: 693:978-0-442-24580-1 378:Incilius alvarius 343:Rhinella diptycha 336:Rhinella arenarum 324:Incilius alvarius 215:dehydrobufotenine 145: 144: 61: 57: 16:(Redirected from 2453: 2441:Amphibian toxins 2413: 2412: 2341: 2297:Histrionicotoxin 2243: 2217: 2209: 2208: 2161: 2115:Alpha-latrotoxin 2103: 1997: 1989: 1988: 1721:Sterigmatocystin 1673:, Fumonisin B3, 1637:epsilon-amanitin 1556:B. thuringiensis 1385:Diphtheria toxin 1328: 1296: 1295: 1265: 1181: 1173: 1172: 1164: 1163: 1153: 1152: 1144: 1143: 1081: 1074: 1067: 1058: 1057: 1032: 1029: 1023: 1022: 1012: 1002: 978: 972: 971: 931: 925: 924: 922: 920: 905: 892: 891: 881: 849: 840: 835: 816:国家药典委员会 (2015). 813: 807: 806: 789: 768: 767: 739: 733: 732: 704: 698: 697: 685: 675: 669: 668: 640: 467: 458: 124: 118: 92: 91:|topic= 89:, and specifying 74:Google Translate 59: 55: 38: 37: 30: 21: 2461: 2460: 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831:9787506773379 827: 823: 819: 812: 804: 798: 794: 788: 786: 784: 782: 780: 778: 776: 774: 765: 761: 757: 753: 749: 745: 738: 730: 726: 722: 718: 714: 711:(in German). 710: 709:Planta Medica 703: 695: 689: 684: 683: 674: 666: 662: 658: 654: 651:(1): 154–60. 650: 646: 639: 635: 627: 624: 618: 615: 613: 610: 608: 605: 603: 600: 598: 595: 593: 590: 588: 585: 582: 579: 577: 574: 572: 571:hallucination 569: 567: 564: 562: 559: 557: 554: 552: 549: 546: 542: 538: 535: 533: 530: 528: 525: 524: 523: 514: 512: 508: 504: 499: 490: 488: 484: 483:resibufogenin 480: 476: 472: 468: 462: 454: 450: 446: 442: 429: 425: 424: 420: 418: 417: 413: 411: 410: 406: 404: 403: 399: 398: 397: 384: 383:Bufo alvarius 380: 379: 375: 374: 373: 370: 366: 365: 361: 359: 358: 354: 352: 351: 347: 345: 344: 340: 338: 337: 333: 330: 329:Bufo alvarius 326: 325: 321: 320: 318: 315: 314: 313: 305: 301: 288: 284: 280: 276: 272: 268: 265: 262: 258: 254: 250: 247: 246: 245: 242: 240: 236: 232: 228: 224: 220: 216: 212: 208: 204: 200: 196: 192: 183: 174: 172: 168: 164: 160: 156: 153: 149: 135: 131: 128: 120: 114: 110: 106: 102: 98: 95: 88: 87:main category 84: 83: 78: 75: 71: 67: 65: 64: 58: 52: 50: 45:You can help 41: 32: 31: 19: 2396: 2375:Calcicludine 2365:Calciseptine 2348:Bungarotoxin 2317:Tarichatoxin 2265:Arenobufagin 2259: 2229:Tetrodotoxin 2188:Tetrodotoxin 2142:Vanillotoxin 2079:Phaiodotoxin 1982:Invertebrate 1905:Solasodamine 1840:Lotaustralin 1675:Fumonisin B4 1671:Fumonisin B2 1667:Fumonisin B1 1653:Cytochalasin 1555: 1535: 1487: 1473: 1467:Superantigen 1459: 1415: 1303:Streptolysin 1244: 1225: 1206: 1187: 1053:, erowid.com 1027: 990: 986: 976: 946:(1): e1–e5. 943: 939: 929: 917:. Retrieved 913: 864:(3): 215–6. 861: 857: 821: 817: 811: 792: 747: 743: 737: 715:(2): 152–3. 712: 708: 702: 681: 673: 648: 644: 638: 625: 621: 520: 507:promethazine 500: 496: 464: 444: 440: 438: 428:Bufo marinus 427: 421: 414: 407: 400: 395: 382: 376: 362: 355: 348: 341: 334: 328: 322: 319:(bufotenin) 311: 303: 279:recreational 251:, which are 243: 230: 211:bufothionine 188: 147: 146: 109:edit summary 100: 80: 54: 46: 2338:Snake venom 2292:Epibatidine 2280:Cinobufagin 2137:Stromatoxin 2084:Imperatoxin 2034:Scyllatoxin 1940:Tagetitoxin 1935:Swainsonine 1925:Solauricine 1890:Solamargine 1885:Scopolamine 1875:Retronecine 1741:Zearalenone 1409:Shiga toxin 1380:Cord factor 1219:Enterotoxin 1214:Alpha toxin 1208:perfringens 1200:Tetanolysin 1178:Clostridium 1115:hepatotoxin 1105:enterotoxin 1095:cardiotoxin 1051:Toad Toxins 556:hypotension 541:ventricular 539:(including 532:bradycardia 503:paracetamol 479:cinobufagin 392:Other toads 275:entheogenic 219:epinephrine 177:Composition 159:tryptamines 2430:Categories 2370:Taicatoxin 2307:Samandarin 2260:Bufotoxins 2224:Ciguatoxin 2202:Vertebrate 2147:Huwentoxin 2127:Cupiennins 2110:Latrotoxin 2054:Kaliotoxin 2024:Margatoxin 2014:Maurotoxin 1955:Toxalbumin 1945:Tinyatoxin 1930:Strychnine 1915:Solasonine 1910:Solasodine 1895:Solanidine 1815:Falcarinol 1800:Delphinine 1716:Phalloidin 1706:Ochratoxin 1701:Orellanine 1691:Lolitrem B 1658:Ergotamine 1608:Mycotoxins 1452:Mechanisms 1411:/Verotoxin 1348:Exfoliatin 1308:Leukocidin 1125:phototoxin 1120:neurotoxin 630:References 511:diclofenac 435:Extraction 426:(formerly 381:(formerly 327:(formerly 298:See also: 285:may raise 267:tryptamine 148:Bufotoxins 18:Bufotoxins 2275:Bufotenin 2270:Bufotalin 2240:Amphibian 2183:Saxitoxin 2173:Eledoisin 2168:Conotoxin 2039:Hefutoxin 1855:Oleandrin 1835:Linamarin 1825:Helenalin 1785:Cicutoxin 1780:Chaconine 1760:Amygdalin 1731:Vomitoxin 1681:Gliotoxin 1663:Fumonisin 1616:Aflatoxin 1579:Virulence 1515:Endotoxin 1246:botulinum 1227:difficile 1137:Bacterial 1110:hemotoxin 1100:cytotoxin 960:0379-0738 836:entries: 818:中华人民共和国药典 581:paralysis 566:tachypnea 409:Bufo bufo 372:5-MeO-DMT 271:bufotenin 261:bufogenin 257:bufotalin 231:bufotoxin 227:serotonin 207:bufotenin 203:bufotalin 191:5-MeO-DMT 171:Bufonidae 127:talk page 79:Consider 51:in French 2415:Category 2178:Onchidal 2158:Mollusca 2069:Bestoxin 2064:Birtoxin 2029:Slotoxin 2019:Agitoxin 1994:Scorpion 1950:Tomatine 1900:Solanine 1845:Mimosine 1820:Gossypol 1805:Divicine 1770:Antiarin 1765:Anisatin 1696:Muscimol 1648:Citrinin 1621:Amatoxin 1567:Cry34Ab1 1495:AB toxin 1489:type III 1401:negative 1159:positive 1148:Exotoxin 1019:33363378 968:19303230 919:22 April 888:17351232 729:84240708 665:13412129 597:vomiting 592:diarrhea 527:paleness 317:5-HO-DMT 195:bufagins 155:lactones 103:provide 2333:Reptile 1795:Daphnin 1790:Coniine 1775:Brucine 1736:Zeranol 1711:Patulin 1558:toxins 1548:Cry3Bb1 1528:Lipid A 1475:type II 1416:E. coli 1168:Bacilli 1010:7752649 879:2660035 764:4871915 561:dyspnea 453:Chinese 294:Species 287:ethical 277:and/or 255:(e.g., 235:bufagin 199:bufalin 152:steroid 125:to the 107:in the 53:. 2205:toxins 2100:Spider 2074:BmKAEP 2044:HgeTx1 1985:toxins 1860:Persin 1753:toxins 1581:factor 1562:Cry6Aa 1554:Other 1543:Cry1Ac 1461:type I 1264:Other: 1189:tetani 1139:toxins 1090:Toxins 1017:  1007:  966:  958:  886:  876:  828:  799:  762:  727:  690:  663:  466:Chánsū 463:: 461:pinyin 455:: 225:, and 2132:PhTx3 2049:HsTx1 1972:Tutin 1965:Ricin 1960:Abrin 1830:Ledol 1751:Plant 1343:delta 1291:Cocci 1252:Botox 820:[ 725:S2CID 471:Latin 237:with 167:toads 70:DeepL 2214:Fish 2122:CSTX 1399:Gram 1339:beta 1157:Gram 1015:PMID 964:PMID 956:ISSN 921:2021 884:PMID 826:ISBN 797:ISBN 760:PMID 688:ISBN 661:PMID 543:and 509:and 481:and 443:and 101:must 99:You 2089:Pi3 2059:Lq2 1499:AB5 1005:PMC 995:doi 948:doi 944:188 874:PMC 866:doi 752:doi 717:doi 653:doi 72:or 2432:: 1669:, 1635:, 1631:, 1627:, 1013:. 1003:. 991:16 989:. 985:. 962:. 954:. 942:. 938:. 912:. 896:^ 882:. 872:. 862:24 860:. 856:. 844:^ 772:^ 758:. 748:56 746:. 723:. 713:52 659:. 649:67 647:. 505:, 473:: 469:; 459:; 457:蟾酥 259:, 241:. 221:, 217:, 213:, 209:, 205:, 201:, 197:, 193:, 2340:: 2335:/ 2242:: 2216:: 2160:: 2102:: 1996:: 1677:) 1665:( 1639:) 1623:( 1497:/ 1425:/ 1341:/ 1337:/ 1238:B 1233:A 1180:: 1080:e 1073:t 1066:v 1021:. 997:: 970:. 950:: 923:. 890:. 868:: 834:. 805:. 766:. 754:: 731:. 719:: 696:. 667:. 655:: 547:) 430:) 385:) 331:) 169:( 136:. 129:. 20:)

Index

Bufotoxins
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steroid
lactones
tryptamines
parotoid glands
toads
Bufonidae

5-MeO-DMT
bufagins
bufalin
bufotalin
bufotenin
bufothionine
dehydrobufotenine
epinephrine
norepinephrine
serotonin
bufagin
suberylarginine

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