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Swedish Orphan Biovitrum

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117: 108: 330: 36: 453:) to jointly develop a drug for hemophilia B, a long-lasting recombinant factor IX Fc fusion protein candidate, rFIXFc. This partnership was extended the following year to also include the development of a long-lasting recombinant factor VIII Fc fusion protein candidate, rFVIIIFc, for the treatment of hemophilia A. 449:, and marketing of specialty pharmaceuticals (ReFacto, Mimpara and Kineret®) was initiated in the Nordic region. In 2005, the research and development portfolio was expanded through the acquisition of Arexis, a Swedish biotech company, and the following year a partnership was formed with Syntonix (subsequently 510:
Sobi is an international specialty healthcare company dedicated to rare diseases with a focus on treatments in haematology, immunology and speciality care. In 2013, Sobi had total revenues of SEK 2.2 billion (€253 M) and about 550 employees; by 2020 the revenue was SEK 15.261 billion and there were
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projects as well as Kiobrina into phase III were taken. The following year the first patient was enrolled in the phase 3 study for Kiobrina and data from the rFVIIIFc hemophilia phase I/II study were presented showing an approximately 1.7-fold increase in half-life compared with Advate. The company
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took the decision to enter final registration studies for the recombinant factor FIXFc. The company also received positive data regarding its Kiobrina phase II program, an investigational enzyme replacement therapy to improve growth in preterm infants who receive pasteurized breast milk or infant
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Sobi has been involved in the process development and manufacturing of recombinant protein drugs since the technology was first developed around 30 years ago, then as part of
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In 2008, an agreement with Amgen regarding the acquisition of the products Kepivance and Stemgen as well as a global license for Kineret was signed
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for ReFacto/Xyntha was extended until 2020 in addition to the agreement to return the co-promotion rights for the Nordic region for ReFacto to
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Guido Oelkers was appointed President and CEO in May 2017, succeeding Geoffrey McDonough. Oelkers had previously been CEO of
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Sobi traces its origins to a subsidiary of Kärnbolaget Aktiebolag Biokemisk Industri in the 1930s, which changed its name to
794: 564: 430:, a process development unit for protein drugs and a plasma product operation. In 2002 Sobi sold its plasma operation to 46: 572: 560: 217: 369: 87: 536: 55: 351: 707: 748: 552: 495:
initiated global pediatric clinical trials of their long-lasting hemophilia A and B product candidates.
516: 145: 17: 583:. The company also market a portfolio of specialty and rare disease products for partner companies. 65: 61: 656: 623: 340: 182: 51: 475:, and Swedish Orphan Biovitrum AB (publ) was formed. In addition, the decisions to advance both 155: 540: 544: 563:, and the 2020 annual report shows a further six products as "pre-market" in the areas of 8: 434:
as part of efforts to concentrate operations on protein-based and small molecular drugs.
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In 2004, Biovitrum started to manufacture the active protein component for
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and MPM Capital Funds. Operations included a research unit focused on
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Treatments in the areas of haematology, immunology and specialty care
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Biovitrum was formed in 2001 through the merger of several units of
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In 2020 it had a revenue of SEK 15.261 billion and 1,509 employees.
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for a payment of USD 47.4 M. The same year, the Sobi and partner
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acquired Swedish Orphan International Holding AB, a pioneer in
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European Biotechnology: Life Science and Industry Magazine
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Change of company name for Biovitrum AB, 2010-06-21
422:) and spun off to a consortium of investors led by 820:"Report for the fourth quarter and year-end 2013" 865: 301:company dedicated to treatments in the areas of 50:, potentially preventing the article from being 889:Pharmaceutical companies established in 2001 644: 642: 640: 638: 636: 586: 894:Manufacturing companies based in Stockholm 879:Companies related to the Wallenberg family 115: 106: 70:reliable, independent, third-party sources 812: 633: 370:Learn how and when to remove this message 88:Learn how and when to remove this message 674: 618: 616: 614: 612: 610: 608: 606: 511:1,509 employees. The share is listed at 64:by replacing them with more appropriate 650:"Annual and Sustainability Report 2020" 624:"Annual and sustainability report 2022" 47:too closely associated with the subject 14: 866: 787: 700: 884:Swedish companies established in 2001 603: 899:Companies listed on Nasdaq Stockholm 765: 352:adding citations to reliable sources 323: 29: 404:to become KabiVitrum in the 1970s. 24: 874:Pharmaceutical companies of Sweden 483:In 2012 the supply agreement with 480:also established a US subsidiary. 25: 915: 848: 749:"Spago Nanomedical AB (SPAGO-SS)" 519:. The company's products include 328: 45:may rely excessively on sources 34: 339:needs additional citations for 286:Footnotes / references 741: 730: 27:Swedish pharmaceutical company 13: 1: 904:2006 initial public offerings 682:"Swedish Orphan Biovitrum AB" 596: 575:, acute graft failure (aGF), 309:and specialty care, based in 7: 591:Synagis (From Astrazeneca) 295:Swedish Orphan Biovitrum AB 101:Swedish Orphan Biovitrum AB 10: 920: 505: 459:In 2009, Sobi and partner 319: 587:Acquisitions and licenses 284: 274: 261: 251: 239: 227: 215: 207: 199: 172: 161: 151: 133: 123: 114: 105: 393:in 1951 and merged with 579:and chronic refractory 547:for several disorders; 825:. Sobi. Archived from 655:. Sobi. Archived from 593:Dova Pharmaceuticals 527:for the treatment of 795:"SOBI: Business Man" 348:improve this article 297:is an international 832:on 30 November 2014 253:Number of employees 102: 775:. Sobi. 4 May 2017 428:metabolic diseases 247:SEK 26.5 bn (2022) 235:SEK 52.5 bn (2022) 223:SEK 14.4 bn (2022) 211:SEK 18.8 bn (2022) 188:Bo Jesper Hansen ( 100: 686:www.bloomberg.com 380: 379: 372: 299:biopharmaceutical 292: 291: 98: 97: 90: 16:(Redirected from 911: 860: 859: 857:Official website 842: 841: 839: 837: 831: 824: 816: 810: 809: 807: 805: 791: 785: 784: 782: 780: 769: 763: 762: 760: 759: 745: 739: 734: 728: 727: 725: 723: 714:. Archived from 704: 698: 697: 695: 693: 678: 672: 671: 669: 667: 661: 654: 646: 631: 630: 628: 620: 513:Nasdaq Stockholm 403: 392: 375: 368: 364: 361: 355: 332: 324: 244: 232: 218:Operating income 142:Nasdaq Stockholm 119: 110: 103: 99: 93: 86: 82: 79: 73: 38: 30: 21: 919: 918: 914: 913: 912: 910: 909: 908: 864: 863: 855: 854: 851: 846: 845: 835: 833: 829: 822: 818: 817: 813: 803: 801: 793: 792: 788: 778: 776: 771: 770: 766: 757: 755: 747: 746: 742: 735: 731: 721: 719: 706: 705: 701: 691: 689: 680: 679: 675: 665: 663: 659: 652: 648: 647: 634: 629:. June 1, 2023. 626: 622: 621: 604: 599: 592: 589: 508: 397: 386: 376: 365: 359: 356: 345: 333: 322: 288: 254: 240: 228: 220: 195: 181:Guido Oelkers ( 175: 138: 94: 83: 77: 74: 59: 39: 28: 23: 22: 15: 12: 11: 5: 917: 907: 906: 901: 896: 891: 886: 881: 876: 862: 861: 850: 849:External links 847: 844: 843: 811: 786: 764: 740: 729: 718:on 25 May 2021 699: 673: 662:on 25 May 2021 632: 601: 600: 598: 595: 588: 585: 507: 504: 424:Nordic Capital 378: 377: 336: 334: 327: 321: 318: 290: 289: 282: 281: 276: 272: 271: 265: 259: 258: 255: 252: 249: 248: 245: 237: 236: 233: 225: 224: 221: 216: 213: 212: 209: 205: 204: 201: 197: 196: 194: 193: 186: 178: 176: 173: 170: 169: 163: 159: 158: 156:Pharmaceutical 153: 149: 148: 139: 134: 131: 130: 125: 121: 120: 112: 111: 96: 95: 42: 40: 33: 26: 9: 6: 4: 3: 2: 916: 905: 902: 900: 897: 895: 892: 890: 887: 885: 882: 880: 877: 875: 872: 871: 869: 858: 853: 852: 828: 821: 815: 800: 796: 790: 774: 768: 754: 750: 744: 738: 733: 717: 713: 709: 703: 687: 683: 677: 658: 651: 645: 643: 641: 639: 637: 625: 619: 617: 615: 613: 611: 609: 607: 602: 594: 584: 582: 578: 574: 570: 566: 562: 558: 554: 550: 546: 542: 538: 534: 530: 526: 522: 518: 514: 503: 501: 496: 494: 490: 486: 481: 478: 474: 470: 465: 462: 457: 454: 452: 448: 444: 440: 435: 433: 429: 425: 421: 417: 412: 410: 405: 401: 396: 390: 385: 374: 371: 363: 353: 349: 343: 342: 337:This section 335: 331: 326: 325: 317: 314: 312: 308: 304: 300: 296: 287: 283: 280: 277: 273: 269: 266: 264: 260: 256: 250: 246: 243: 238: 234: 231: 226: 222: 219: 214: 210: 206: 202: 198: 191: 187: 184: 180: 179: 177: 171: 167: 164: 160: 157: 154: 150: 147: 143: 140: 137: 132: 129: 126: 122: 118: 113: 109: 104: 92: 89: 81: 71: 67: 63: 57: 53: 49: 48: 43:This article 41: 37: 32: 31: 19: 834:. 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Bloomberg 569:haemophilia 529:haemophilia 500:BSN Medical 493:Biogen Idec 461:Biogen Idec 451:Biogen Idec 398: [ 387: [ 303:haematology 268:Investor AB 868:Categories 758:2022-09-14 597:References 477:hemophilia 447:hemophilia 432:Octapharma 409:KabiVitrum 313:, Sweden. 307:immunology 174:Key people 62:improve it 52:verifiable 708:"History" 469:Biovitrum 467:In 2010, 464:formula. 416:Pharmacia 311:Stockholm 166:Stockholm 136:Traded as 66:citations 18:Biovitrum 753:biotickr 557:Gamifant 533:Doptelet 525:Alprolix 441:’s (now 360:May 2020 279:sobi.com 200:Products 190:chairman 168:, Sweden 152:Industry 78:May 2020 549:Synagis 545:Kineret 515::  506:Company 320:History 275:Website 270:(34.7%) 208:Revenue 144::  56:neutral 836:25 May 722:25 May 666:25 May 521:Elocta 489:Pfizer 485:Pfizer 443:Pfizer 420:Pfizer 395:Vitrum 263:Parent 128:Public 830:(PDF) 823:(PDF) 804:6 May 779:6 May 692:7 May 660:(PDF) 653:(PDF) 627:(PDF) 439:Wyeth 418:(now 402:] 391:] 838:2021 806:2020 781:2020 724:2021 712:Sobi 694:2020 668:2021 581:gout 573:sHLH 561:pHLH 559:for 555:and 551:for 539:and 535:for 523:and 517:SOBI 384:Kabi 146:SOBI 54:and 577:ALS 565:PNH 553:RSV 543:; 541:CLD 537:ITP 350:by 183:CEO 68:to 870:: 797:. 751:. 710:. 684:. 635:^ 605:^ 571:, 567:, 531:; 502:. 411:. 400:sv 389:sv 305:, 840:. 808:. 783:. 761:. 726:. 696:. 670:. 373:) 367:( 362:) 358:( 344:. 192:) 185:) 91:) 85:( 80:) 76:( 72:. 58:. 20:)

Index

Biovitrum

too closely associated with the subject
verifiable
neutral
improve it
citations
reliable, independent, third-party sources
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Public
Traded as
Nasdaq Stockholm
SOBI
Pharmaceutical
Stockholm
CEO
chairman
Operating income
Total assets
Total equity
Parent
Investor AB
sobi.com
biopharmaceutical
haematology
immunology
Stockholm

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