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11-Dehydrothromboxane B2

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24: 360: 112: 262:
InChI=1S/C20H32O6/c1-2-3-6-9-15(21)12-13-18-16(17(22)14-20(25)26-18)10-7-4-5-8-11-19(23)24/h4,7,12-13,15-18,21-22H,2-3,5-6,8-11,14H2,1H3,(H,23,24)/b7-4-,13-12+/t15-,16-,17-,18+/m0/s1
272:
InChI=1/C20H32O6/c1-2-3-6-9-15(21)12-13-18-16(17(22)14-20(25)26-18)10-7-4-5-8-11-19(23)24/h4,7,12-13,15-18,21-22H,2-3,5-6,8-11,14H2,1H3,(H,23,24)/b7-4-,13-12+/t15-,16-,17-,18+/m0/s1
373: 426:"A comparison of six major platelet function tests to determine the prevalence of aspirin resistance in patients with stable coronary artery disease" 288: 368: 174: 253: 403:. It is released by activated platelets and urine levels of 11-dehydro-TXB2 can be used to monitor the response to 380: 230: 467:"11-Dehydrothromboxane B2: a quantitative index of thromboxane A2 formation in the human circulation" 407:
therapy when used to prevent heart disease and in diseases where platelet activation is prominent.
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Lordkipanidzé M, Pharand C, Schampaert E, Turgeon J, Palisaitis DA, Diodati JG (2007).
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Except where otherwise noted, data are given for materials in their
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Catella F, Healy D, Lawson JA, FitzGerald GA (1986).
173: 522: 218: 87: 57:)-4-Hydroxy-2--6-oxooxan-3-yl}hept-5-enoic acid 296:O=C1O(/C=C/(O)CCCCC)((O)C1)C\C=C/CCCC(=O)O 151: 500: 490: 441: 238: 523: 265:Key: KJYIVXDPWBUJBQ-UHHGALCXSA-N 131: 399:) is produced from the breakdown of 275:Key: KJYIVXDPWBUJBQ-UHHGALCXBE 209: 193: 13: 14: 542: 358: 323: 22: 354:(at 25 °C , 100 kPa). 458: 417: 329: 317: 1: 410: 7: 10: 547: 348: 304: 284: 249: 71: 66:11-Dehydro-thromboxane B2 63: 35: 30: 21: 17:11-Dehydrothromboxane B2 443:10.1093/eurheartj/ehm226 393:11-Dehydrothromboxane B2 492:10.1073/pnas.83.16.5861 344:368.46 37:Preferred IUPAC name 483:1986PNAS...83.5861C 18: 381:Infobox references 16: 477:(16): 5861–5865. 436:(14): 1702–1708. 389:Chemical compound 387: 386: 113:Interactive image 538: 515: 514: 504: 494: 462: 456: 455: 445: 421: 371: 365: 362: 361: 331: 325: 319: 312:Chemical formula 242: 222: 211: 197: 177: 155: 135: 115: 91: 26: 19: 15: 546: 545: 541: 540: 539: 537: 536: 535: 521: 520: 519: 518: 463: 459: 422: 418: 413: 397:11-dehydro-TXB2 390: 383: 378: 377: 376:  ?) 367: 363: 359: 355: 334: 328: 322: 314: 300: 297: 292: 291: 280: 277: 276: 273: 267: 266: 263: 257: 256: 245: 225: 212: 200: 180: 167: 158: 138: 118: 105: 94: 81: 67: 59: 58: 12: 11: 5: 544: 534: 533: 517: 516: 457: 415: 414: 412: 409: 401:thromboxane A2 388: 385: 384: 379: 357: 356: 352:standard state 349: 346: 345: 342: 336: 335: 332: 326: 320: 315: 310: 307: 306: 302: 301: 299: 298: 295: 287: 286: 285: 282: 281: 279: 278: 274: 271: 270: 268: 264: 261: 260: 252: 251: 250: 247: 246: 244: 243: 235: 233: 227: 226: 224: 223: 215: 213: 205: 202: 201: 199: 198: 190: 188: 182: 181: 179: 178: 170: 168: 163: 160: 159: 157: 156: 148: 146: 140: 139: 137: 136: 128: 126: 120: 119: 117: 116: 108: 106: 99: 96: 95: 93: 92: 84: 82: 77: 74: 73: 69: 68: 65: 61: 60: 40: 39: 33: 32: 28: 27: 9: 6: 4: 3: 2: 543: 532: 529: 528: 526: 512: 508: 503: 498: 493: 488: 484: 480: 476: 472: 468: 461: 453: 449: 444: 439: 435: 431: 427: 420: 416: 408: 406: 402: 398: 394: 382: 375: 370: 353: 347: 343: 341: 338: 337: 316: 313: 309: 308: 303: 294: 293: 290: 283: 269: 259: 258: 255: 248: 241: 237: 236: 234: 232: 229: 228: 221: 217: 216: 214: 208: 204: 203: 196: 192: 191: 189: 187: 184: 183: 176: 172: 171: 169: 166: 162: 161: 154: 150: 149: 147: 145: 142: 141: 134: 130: 129: 127: 125: 122: 121: 114: 110: 109: 107: 103: 98: 97: 90: 86: 85: 83: 80: 76: 75: 70: 62: 56: 52: 48: 44: 38: 34: 29: 25: 20: 474: 470: 460: 433: 429: 419: 396: 392: 391: 72:Identifiers 64:Other names 54: 50: 46: 42: 531:Eicosanoids 430:Eur Heart J 305:Properties 133:CHEBI:28667 411:References 340:Molar mass 240:CJ6ST9UG7C 165:IUPHAR/BPS 144:ChemSpider 100:3D model ( 89:67910-12-7 79:CAS Number 525:Category 452:17569678 511:3461463 479:Bibcode 405:aspirin 374:what is 372: ( 220:5280891 207:PubChem 153:4444414 45:)-7-{(2 509:  502:386396 499:  450:  369:verify 366:  289:SMILES 195:C05964 31:Names 254:InChI 124:ChEBI 102:JSmol 507:PMID 471:PNAS 448:PMID 395:(or 231:UNII 186:KEGG 175:4484 497:PMC 487:doi 438:doi 210:CID 527:: 505:. 495:. 485:. 475:83 473:. 469:. 446:. 434:28 432:. 428:. 327:32 321:20 53:,4 49:,3 41:(5 513:. 489:: 481:: 454:. 440:: 364:N 333:6 330:O 324:H 318:C 104:) 55:S 51:S 47:R 43:Z

Index


Preferred IUPAC name
CAS Number
67910-12-7
JSmol
Interactive image
ChEBI
CHEBI:28667
ChemSpider
4444414
IUPHAR/BPS
4484
KEGG
C05964
PubChem
5280891
UNII
CJ6ST9UG7C
InChI
SMILES
Chemical formula
Molar mass
standard state
verify
what is
Infobox references
thromboxane A2
aspirin
"A comparison of six major platelet function tests to determine the prevalence of aspirin resistance in patients with stable coronary artery disease"
doi

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