Knowledge

Thrombocytopenia

Source đź“ť

527: 845:(ITP), also known as idiopathic thrombocytopenic purpura, can be left untreated, and spontaneous remission (especially in children) is not uncommon. However, counts under 50,000/ÎĽL are usually monitored with regular blood tests, and those with counts under 10,000/ÎĽL are usually treated, as the risk of serious spontaneous bleeding is high with such low platelet counts. Any patient experiencing severe bleeding symptoms is also usually treated. The threshold for treating ITP has decreased since the 1990s; 4198: 168: 4228: 176: 51: 4238: 2772: 834: 4218: 4208: 248:, and general weakness (with or without accompanying blood loss). Acquired thrombocytopenia may be associated with the use of certain drugs. Inspection typically reveals evidence of bleeding (petechiae or ecchymoses), along with slow, continuous bleeding from any injuries or wounds. Adults may have large, blood-filled 751:
Treatment is guided by the severity and specific cause of the disease. Treatment focuses on eliminating the underlying problem, whether that means discontinuing drugs suspected to cause it or treating underlying sepsis. Diagnosis and treatment of serious thrombocytopenia is usually directed by a
950:
Thrombocytopenia affects a few newborns, and its prevalence in neonatal intensive care units is high. Normally, it is mild and resolves without consequences. Most cases affect preterm birth infants and result from placental insufficiency and/or fetal hypoxia. Other causes, such as alloimmunity,
146:
A normal human platelet count ranges from 150,000 to 450,000 platelets/microliter (ÎĽL) of blood. Values outside this range do not necessarily indicate disease. One common definition of thrombocytopenia requiring emergency treatment is a platelet count below 50,000/ÎĽL. Thrombocytopenia can be
736:, and most frequently, the direct toxic effect of alcohol on production, survival time, and function of platelets. Platelet count begins to rise after 2 to 5 days' abstinence from alcohol. The condition is generally benign, and clinically significant hemorrhage is rare. 373: 925:
Bone marrow/stem cell transplants are the only known cures for this genetic disease. Frequent platelet transfusions are required to keep the patient from bleeding to death before the transplant can be performed, although this is not always the case.
818:
to the patient, restoring a normal level of von Willebrand factor multimers. Patients with persistent antibodies against ADAMTS-13 do not always manifest TTP, and these antibodies alone are not sufficient to explain how plasmapheresis treats TTP.
343: 252:
in the mouth. If the person's platelet count is between 30,000 and 50,000/ÎĽL, bruising with minor trauma may be expected; if it is between 15,000 and 30,000/ÎĽL, spontaneous bruising will be seen (mostly on the arms and legs).
2451:
Rempen A, Martius J, Hartmann AA, Wecker I (1987). "Transmission rate of Ureaplasma urealyticum, Mycoplasma spp., Gardnerella vaginalis, B-streptococci, Candida spp. and Chlamydia trachomatis from the mother to the newborn".
2711: 2696: 414: 1893: 2407:
Pacifico L, Chiesa C, Mirabella S, Panero A, Midulla M (March 1987). "Early-onset Pseudomonas aeruginosa sepsis and Yersinia enterocolitica neonatal infection: a unique combination in a preterm infant".
513: 488: 431: 353: 885:
Discontinuation of heparin is critical in a case of heparin-induced thrombocytopenia (HIT). Beyond that, however, clinicians generally treat to avoid thrombosis. Treatment may include a
348: 1535: 467: 448: 2544:
Kotiw M, Zhang GW, Daggard G, Reiss-Levy E, Tapsall JW, Numa A (2003). "Late-onset and recurrent neonatal Group B streptococcal disease associated with breast-milk transmission".
493: 477: 338: 389: 378: 1425: 1361: 404: 1695: 852:
Thrombopoetin analogues have been tested extensively for the treatment of ITP. These agents had previously shown promise, but had been found to stimulate antibodies against
1657: 1822: 796: 791:
and platelet activation can lead to kidney failure and changes in the level of consciousness. Treatment of TTP was revolutionized in the 1980s with the application of
233:, are not also suppressed, is also important. Painless, round, and pinpoint (1 to 3 mm in diameter) petechiae usually appear and fade, and sometimes group to form 2369:
Guida JD, Kunig AM, Leef KH, McKenzie SE, Paul DA (June 2003). "Platelet count and sepsis in very low birth weight neonates: is there an organism-specific response?".
2265: 1755: 2818: 1508:
Almazni I, Stapley R, Morgan NV (2019) Inherited Thrombocytopenia: Update on genes and genetic variants which may be associated With bleeding. Front Cardiovasc Med
225:
Eliciting a full medical history is vital to ensure the low platelet count is not secondary to another disorder. Ensuring that the other blood cell types, such as
1877: 935: 849:
recognize that patients rarely spontaneously bleed with platelet counts greater than 10,000/ÎĽL, although exceptions to this observation have been documented.
939: 472: 743:. This information may identify ineffective platelet production as the cause of thrombocytopenia and rule out a malignant disease process at the same time. 462: 399: 1280: 237:. Larger than petechiae, ecchymoses are purple, blue, or yellow-green areas of skin that vary in size and shape. They can occur anywhere on the body. 1044:. The severity of thrombocytopenia may be correlated with pathogen type; some research indicates that the most severe cases are related to fungal or 1916:"Use of platelet transfusions prior to lumbar punctures or epidural anaesthesia for the prevention of complications in people with thrombocytopenia" 1784: 2107: 2012: 1724: 934:
Human-induced pluripotent stem cell-derived platelets is a technology currently being researched by the private sector, in association with the
867:(trade name Nplate, formerly AMG 531) was found to be safe and effective for the treatment of ITP in refractory patients, especially those who 1454: 966:
tests may be useful for rapid pathogen identification and detection of antibiotic-resistance genes. Possible pathogens include viruses (e.g.
2811: 2629: 1519: 1477: 1125: 368: 2235: 2145: 2078: 1557: 1187: 3727: 2589:"Transmission of community-associated methicillin-resistant Staphylococcus aureus from breast milk in the neonatal intensive care unit" 2049: 1216: 1086: 4068: 1409: 1345: 2804: 1679: 1641: 3667: 1844: 1806: 2935: 1914:
Estcourt LJ, Malouf R, Hopewell S, Doree C, Van Veen J, et al. (Cochrane Haematological Malignancies Group) (April 2018).
553: 725:
is usually recommended to differentiate cases of decreased platelet production from cases of peripheral platelet destruction.
1155: 2257: 3967: 1745: 1056:
is being investigated as a drug for managing thrombocytopenia, especially in cases of sepsis or necrotizing enterocolitis.
578: 3110: 3093: 784: 558: 543: 4103: 3445: 1119: 2229: 2139: 2043: 1887: 1854: 1816: 1689: 1651: 1567: 1529: 1487: 1419: 1392: 1355: 17: 1319: 3172: 3124: 880: 453: 842: 828: 664: 538: 4221: 4093: 3527: 2891: 718: 526: 482: 3178: 3164: 1272: 548: 409: 4073: 3152: 3115: 2985: 568: 503: 498: 358: 2787: 3717: 3305: 2881: 1347:
Chamberlain's Symptoms and Signs in Clinical Medicine 13th Edition, An Introduction to Medical Diagnosis
3697: 3260: 3105: 534:
Abnormally high rates of platelet destruction may be due to immune or nonimmune conditions, including:
2099: 2004: 1776: 4126: 3376: 2947: 2928: 1716: 963: 959: 954:
Thrombocytopenia that starts after the first 72 hours, since birth is often the result of underlying
886: 563: 508: 78:
Bone marrow not making enough platelets, body destroying platelets, spleen holding too many platelets
2035:
Thrombocytopenic Purpura: New Insights for the Healthcare Professional: 2013 Edition: ScholarlyPaper
739:
In severe thrombocytopenia, a bone marrow study can determine the number, size, and maturity of the
4272: 3918: 3840: 3835: 3755: 3515: 3346: 3089: 2918: 2726: 1591:"Pseudothrombocytopenia due to Platelet Clumping: A Case Report and Brief Review of the Literature" 1446: 992: 690: 573: 425: 294: 4262: 3898: 3872: 3336: 3129: 1028: 436: 362: 2653: 4267: 3490: 3438: 3250: 3225: 3183: 1022: 1010: 998: 419: 277: 2070: 1382: 1179: 1109: 913:
are not routinely used to treat HIT because thrombosis, not bleeding, is the primary problem.
4141: 4027: 4000: 3973: 3925: 3879: 3574: 3245: 3235: 3053: 2219: 2129: 1016: 804: 651: 2033: 1208: 4161: 4121: 3988: 3802: 3797: 3777: 3712: 3564: 3001: 2896: 2886: 1078: 910: 772: 593: 191: 140: 136: 103: 88: 8: 4241: 4183: 4166: 3825: 3542: 3240: 3230: 3026: 2906: 2715: 721:, and peripheral blood smear. If the cause for the low platelet count remains unclear, a 325: 249: 2777: 4131: 4088: 4078: 3867: 3820: 3787: 3782: 3532: 3510: 3366: 3048: 3006: 2980: 2853: 2605: 2588: 2569: 2521: 2496: 2477: 2433: 2333: 2308: 2195: 2170: 1940: 1915: 1617: 1590: 722: 99: 2720: 4227: 4201: 4083: 4053: 4032: 3995: 3978: 3893: 3857: 3847: 3742: 3662: 3606: 3569: 3554: 3495: 3462: 3431: 3255: 3031: 2940: 2796: 2645: 2610: 2561: 2526: 2469: 2425: 2386: 2338: 2225: 2200: 2135: 2039: 1986: 1945: 1883: 1850: 1812: 1685: 1647: 1622: 1563: 1525: 1483: 1415: 1388: 1351: 1254: 1161: 1151: 1115: 1040: 761: 733: 457: 284: 230: 83: 63: 2573: 2481: 2437: 4211: 3903: 3888: 3765: 3640: 3596: 3021: 3016: 2876: 2600: 2553: 2516: 2508: 2461: 2417: 2378: 2328: 2320: 2190: 2182: 1976: 1935: 1931: 1927: 1612: 1602: 1246: 1034: 1004: 788: 775:
may be suggested for people who have a low platelet count due to thrombocytopenia.
702: 684: 383: 219: 194:. Some individuals with thrombocytopenia may experience external bleeding, such as 1965:"Thrombotic microangiopathies, thrombotic thrombocytopenic purpura, and ADAMTS-13" 1678:
Greer JP, Arber DA, Glader B, List AF, Means RT, Paraskevas F, Rodgers GM (2013).
4231: 4176: 4037: 4022: 4005: 3945: 3940: 3884: 3862: 3559: 3505: 3485: 3361: 3195: 3036: 2901: 2731: 967: 757: 710: 298: 226: 152: 1048:
bacterial infection. The pathogen may be transmitted during or before birth, by
764:
or folate may also be used to stimulate platelet production in the bone marrow.
4063: 4017: 3830: 3760: 3579: 3386: 3098: 3041: 2923: 2755: 1053: 1049: 980: 898: 856: 792: 609:
These medications can induce thrombocytopenia through direct myelosuppression:
394: 304: 156: 2705: 2557: 1808:
Medical and Nutritional Complications of Alcoholism: Mechanisms and Management
1165: 4256: 4146: 3935: 3930: 3792: 3732: 3635: 3396: 3218: 3213: 3208: 2965: 2497:"Neonatal group B streptococcal disease associated with infected breast milk" 2186: 1045: 971: 740: 613: 583: 330: 312: 143:
and is seen in a fifth of medical patients and a third of surgical patients.
3139: 2382: 4151: 4136: 3962: 3687: 3537: 3522: 3468: 3406: 2848: 2649: 2614: 2565: 2530: 2390: 2342: 2204: 1990: 1981: 1964: 1949: 1626: 1607: 1258: 986: 906: 846: 753: 729: 706: 679: 638: 633: 618: 588: 203: 187: 180: 2473: 2429: 1559:
Platelets in Hematologic and Cardiovascular Disorders: A Clinical Handbook
4010: 3955: 3852: 3707: 3682: 3500: 3203: 3011: 2843: 2832: 2324: 1843:
Hillyer CD, Abrams CS, Shaz BH, Roshal M, Zimring JC, Abshire TC (2009).
1750: 1308: 1250: 902: 864: 623: 273: 107: 2627: 2512: 929: 179:
Right upper limb with purpura caused by thrombocytopenia in person with
4098: 3983: 3950: 3722: 3672: 3657: 3652: 3645: 3630: 3620: 3391: 3356: 3331: 2975: 2957: 2750: 2465: 2421: 894: 860: 853: 800: 643: 628: 598: 234: 116: 68: 2688: 167: 4171: 3913: 3908: 3772: 3750: 3625: 3589: 3381: 3326: 2913: 890: 674: 374:
Congenital amegakaryocytic thrombocytopenia and radioulnar synostosis
195: 175: 131:. Low levels of platelets in turn may lead to prolonged or excessive 50: 1846:
Transfusion Medicine and Hemostasis: Clinical and Laboratory Aspects
3677: 3454: 3295: 3290: 3280: 2970: 2828: 2171:"Heparin induced thrombocytopenia: diagnosis and management update" 914: 815: 814:. The plasmapheresis procedure also adds active ADAMTS-13 protease 811: 808: 290: 215: 207: 132: 124: 4156: 3616: 3584: 3477: 3341: 3300: 1309:"B.E. Project on Platlet Count Using Image Processing Techniques" 868: 833: 245: 241: 211: 3285: 2700: 2628:
Jagielski M, Rastawicki W, Kałuzewski S, Gierczyński R (2007).
955: 317: 920: 2587:
Gastelum DT, Dassey D, Mascola L, Yasuda LM (December 2005).
2406: 728:
Thrombocytopenia in hospitalized alcoholics may be caused by
321: 308: 147:
contrasted with the conditions associated with an abnormally
128: 2501:
Archives of Disease in Childhood. Fetal and Neonatal Edition
2313:
Archives of Disease in Childhood. Fetal and Neonatal Edition
344:
Amegakaryocytic thrombocytopenia with radio-ulnar synostosis
3423: 2586: 2543: 2450: 1913: 1556:
Gresele P, Fuster V, Lopez JA, Page CP, Vermylen J (2007).
442: 199: 2632:[Yersiniosis – unappreciated infectious diseases] 1589:
Tan GC, Stalling M, Dennis G, Nunez M, Kahwash SB (2016).
951:
genetics, autoimmunity, and infection, are less frequent.
445:-related disease (associated with giant platelet disorder) 2630:"[Yersiniosis--unappreciated infectious disease]" 975: 123:
is a condition characterized by abnormally low levels of
1475: 1387:. Lippincott Williams & Wilkins. 2007. p. 293. 837:
Oral petechiae/purpura - immune thrombocytopenic purpura
222:, may be caused by spontaneous bleeding under the skin. 1842: 58:
A photomicrograph of the blood showing thrombocytopenia
2826: 2495:
Olver WJ, Bond DW, Boswell TC, Watkin SL (July 2000).
2494: 2368: 1588: 1555: 942:, that would create platelets outside the human body. 936:
Biomedical Advanced Research and Development Authority
778: 2005:"How Is Thrombotic Thrombocytopenic Purpura Treated?" 1962: 930:
Human-induced pluripotent stem cell-derived platelets
269:
Abnormally low platelet production may be caused by:
2678: 1677: 917:
is not recommended until platelets have normalized.
701:
Laboratory tests for thrombocytopenia might include
663:
Laboratory error, possibly due to the anticoagulant
2127: 1517: 1476:Fiebach NH, Barker LR, Burton JR, Zieve PD (2007). 874: 787:(TTP) is a medical emergency, since the associated 2309:"Neonatal thrombocytopenia: causes and management" 1875: 1639: 822: 2168: 2100:"Nplate (romiplostim) for subcutaneous injection" 2009:National Heart, Lung, and Blood Institute (NHLBI) 1963:Chapman K, Seldon M, Richards R (February 2012). 1781:National Heart, Lung, and Blood Institute (NHLBI) 1451:National Heart, Lung, and Blood Institute (NHLBI) 1277:National Heart, Lung, and Blood Institute (NHLBI) 1213:National Heart, Lung, and Blood Institute (NHLBI) 1107: 1083:National Heart, Lung, and Blood Institute (NHLBI) 4254: 2011:. U.S. Department of Health and Human Services. 1783:. U.S. Department of Health and Human Services. 1521:Hematology: Clinical Principles and Applications 1453:. U.S. Department of Health and Human Services. 1279:. U.S. Department of Health and Human Services. 1215:. U.S. Department of Health and Human Services. 1085:. U.S. Department of Health and Human Services. 240:A person with this disease may also complain of 171:Petechiae on the lower leg from thrombocytopenia 2364: 2362: 2360: 2358: 2356: 2354: 2352: 2258:"New technology may aid emergency preparedness" 1407: 1148:Critical care medicine: the essentials and more 261:Thrombocytopenia can be inherited or acquired. 27:Abnormally low levels of platelets in the blood 2402: 2400: 2169:Ahmed I, Majeed A, Powell R (September 2007). 1876:Lawrence PF, Bell RM, Dayton MT (2012-10-31). 3439: 2812: 2306: 760:may be used to increase platelet production. 415:GNE myopathy with congenital thrombocytopenia 2580: 2537: 2488: 2444: 2349: 2217: 1582: 1343: 1302: 1300: 1298: 945: 940:U.S. Department of Health and Human Services 2397: 2071:"Idiopathic thrombocytopenic purpura (ITP)" 1920:The Cochrane Database of Systematic Reviews 1502: 1237:Schafer AI (March 2004). "Thrombocytosis". 1145: 921:Congenital amegakaryocytic thrombocytopenia 369:Congenital amegakaryocytic thrombocytopenia 3728:Reproductive endocrinology and infertility 3446: 3432: 2819: 2805: 2621: 671:platelet count is a useful follow-up study 514:X-linked thrombocytopenia with thalassemia 49: 4069:Bachelor of Medicine, Bachelor of Surgery 2604: 2520: 2332: 2224:. Springer Science & Business Media. 2194: 2164: 2162: 2128:Warkentin TE, Greinacher A (2007-07-23). 1980: 1939: 1811:. Springer Science & Business Media. 1616: 1606: 1295: 1073: 1071: 1069: 901:" sometimes used in this setting include 439:(associated with giant platelet disorder) 428:(associated with giant platelet disorder) 422:(associated with giant platelet disorder) 386:(associated with giant platelet disorder) 2593:The Pediatric Infectious Disease Journal 1518:Rodak BF, Fritsma GA, Keohane E (2013). 1111:Evidence-based Practice of Critical Care 832: 767: 525: 521: 202:. Some women may have heavier or longer 174: 166: 3073: 2307:Roberts I, Murray NA (September 2003). 1236: 264: 14: 4255: 2302: 2159: 1804: 1325:from the original on 10 September 2016 1066: 554:Disseminated intravascular coagulation 489:Tropomyosin 4-related thrombocytopenia 432:Macrothrombocytopenia and hearing loss 3427: 2800: 2546:Pediatric and Developmental Pathology 2454:Archives of Gynecology and Obstetrics 2300: 2298: 2296: 2294: 2292: 2290: 2288: 2286: 2284: 2282: 2255: 2077:. U.S. National Library of Medicine. 1969:Seminars in Thrombosis and Hemostasis 1882:. Lippincott Williams & Wilkins. 1723:. U.S. National Library of Medicine. 1684:. Lippincott Williams & Wilkins. 1640:Waldmann C, Soni N, Rhodes A (2008). 1482:. Lippincott Williams & Wilkins. 1414:. Lippincott Williams & Wilkins. 1186:. U.S. National Library of Medicine. 1089:from the original on 25 November 2020 604: 162: 4207: 3968:Physical medicine and rehabilitation 1777:"How Is Thrombocytopenia Diagnosed?" 1746:"Niemann-Pick - Symptoms and causes" 1643:Oxford Desk Reference: Critical Care 1457:from the original on 2 December 2014 1273:"Thrombocythemia and Thrombocytosis" 579:Neonatal alloimmune thrombocytopenia 127:(also known as thrombocytes) in the 4217: 1439: 1265: 1239:The New England Journal of Medicine 799:, this treatment works by removing 785:thrombotic thrombocytopenic purpura 779:Thrombotic thrombocytopenic purpura 559:Paroxysmal nocturnal hemoglobinuria 544:Thrombotic thrombocytopenic purpura 354:Autosomal dominant thrombocytopenia 24: 4104:Medical Scientist Training Program 2606:10.1097/01.inf.0000189983.71585.30 2279: 1306: 1108:Deutschman CS, Neligan PJ (2010). 151:level of platelets in the blood – 25: 4284: 2674: 2221:Neonatology and Blood Transfusion 2038:. ScholarlyEditions. 2013-07-22. 1479:Principles of Ambulatory Medicine 1283:from the original on 14 June 2019 155:(when the cause is unknown), and 4236: 4226: 4216: 4206: 4197: 4196: 3173:platelet storage pool deficiency 3125:Heparin-induced thrombocytopenia 2770: 2131:Heparin-Induced Thrombocytopenia 2075:MedlinePlus Medical Encyclopedia 1408:Rosdahl CB, Kowalski MT (2008). 1184:MedlinePlus Medical Encyclopedia 1150:. Philadelphia: Wolters Kluwer. 881:Heparin-induced thrombocytopenia 875:Heparin-induced thrombocytopenia 454:Paris-Trousseau thrombocytopenia 349:ANKRD26 related thrombocytopenia 4237: 2268:from the original on 2019-10-05 2249: 2238:from the original on 2023-01-11 2211: 2148:from the original on 2023-01-11 2121: 2110:from the original on 2016-03-11 2092: 2081:from the original on 2015-04-06 2063: 2052:from the original on 2023-01-11 2026: 2015:from the original on 2015-05-01 1997: 1956: 1907: 1896:from the original on 2023-01-11 1869: 1836: 1825:from the original on 2023-01-11 1798: 1787:from the original on 2015-05-25 1769: 1758:from the original on 2020-08-04 1738: 1727:from the original on 2018-09-24 1709: 1698:from the original on 2023-01-11 1671: 1660:from the original on 2023-01-11 1633: 1549: 1538:from the original on 2023-01-11 1511: 1469: 1447:"What Causes Thrombocytopenia?" 1428:from the original on 2023-01-11 1401: 1384:Interpreting Signs and Symptoms 1375: 1364:from the original on 2023-01-11 1219:from the original on 2015-05-18 1190:from the original on 2015-04-05 1128:from the original on 2023-01-11 843:immune thrombocytopenic purpura 829:Immune thrombocytopenic purpura 823:Immune thrombocytopenic purpura 657: 539:Immune thrombocytopenic purpura 468:SLFN14-related thrombocytopenia 449:PRKACG-related thrombocytopenia 44:Thrombocytopaenia, thrombopenia 4094:Doctor of Osteopathic Medicine 3528:Oral and maxillofacial surgery 2892:Activated protein C resistance 2410:European Journal of Pediatrics 2218:Smit-Sibinga CH (2010-05-10). 1932:10.1002/14651858.CD011980.pub3 1681:Wintrobe's Clinical Hematology 1562:. Cambridge University Press. 1337: 1230: 1201: 1172: 1139: 1101: 719:erythrocyte sedimentation rate 687:(also called plateletpheresis) 494:TUBB1-related thrombocytopenia 483:Thrombocytopenia absent radius 478:TRPM7-related thrombocytopenia 339:ACTN1-related thrombocytopenia 190:and is picked up on a routine 108:surgical removal of the spleen 13: 1: 1879:Essentials of General Surgery 1059: 390:ETV6 related thrombocytopenia 379:CYCS-related thrombocytopenia 4074:Bachelor of Medical Sciences 3841:Neurosurgical anesthesiology 3453: 2986:Trousseau sign of malignancy 2175:Postgraduate Medical Journal 1524:. Elsevier Health Sciences. 1344:Houghton AR, Gray D (2010). 1146:Marini JJ, Dries DJ (2019). 1114:. Elsevier Health Sciences. 962:. In the case of infection, 746: 696: 569:Systemic lupus erythematosus 405:FYB related thrombocytopenia 7: 3306:Nonthrombocytopenic purpura 2882:Antithrombin III deficiency 1646:. Oxford University Press. 1209:"What Is Thrombocytopenia?" 717:levels, folic acid levels, 159:(when the cause is known). 10: 4289: 3261:Congenital afibrinogenemia 3165:Glanzmann's thrombasthenia 2262:Homeland Preparedness News 1595:Case Reports in Hematology 878: 826: 410:Glanzmann's thrombasthenia 206:or breakthrough bleeding. 4192: 4114: 4052: 3813: 3741: 3696: 3605: 3476: 3461: 3377:Gastrointestinal bleeding 3316: 3273: 3194: 3179:Hermansky–Pudlak syndrome 3138: 3080: 3066: 2994: 2956: 2948:Antiphospholipid syndrome 2929:Essential thrombocythemia 2869: 2862: 2839: 2741: 2682: 2638:Przeglad Epidemiologiczny 2558:10.1007/s10024-001-0276-y 1411:Textbook of Basic Nursing 1052:, or during transfusion. 964:polymerase chain reaction 960:necrotizing enterocolitis 946:Neonatal thrombocytopenia 887:direct thrombin inhibitor 667:in CBC specimen tubes; a 564:Antiphospholipid syndrome 549:Hemolytic–uremic syndrome 509:X-linked thrombocytopenia 256: 186:Thrombocytopenia usually 135:. It is the most common 94: 82: 74: 62: 57: 48: 40: 35: 4028:Transplantation medicine 3919:Clinical neurophysiology 3836:Obstetric anesthesiology 3756:Interventional radiology 3516:Digestive system surgery 3347:Subconjunctival bleeding 3153:Bernard–Soulier syndrome 3116:Upshaw–Schulman syndrome 3090:Thrombocytopenic purpura 2919:Sticky platelet syndrome 2187:10.1136/pgmj.2007.059188 993:Streptococcus agalactiae 574:Post-transfusion purpura 504:Wiskott–Aldrich syndrome 499:Upshaw–Schulman syndrome 426:Harris platelet syndrome 359:Bernard–Soulier syndrome 303:Decreased production of 295:myelodysplastic syndrome 3899:Intensive care medicine 3873:Mass gathering medicine 3718:Maternal–fetal medicine 3337:Intracranial hemorrhage 2383:10.1542/peds.111.6.1411 1721:Genetics Home Reference 1029:Yersinia enterocolitica 871:following splenectomy. 363:giant platelet disorder 218:in the feet, legs, and 141:intensive care patients 3491:Cardiothoracic surgery 3251:Factor XIII deficiency 3231:Hypoprothrombinemia/II 3226:von Willebrand disease 3184:Gray platelet syndrome 2256:Clark D (2019-10-02). 1982:10.1055/s-0031-1300951 1717:"Niemann-Pick disease" 1023:Pseudomonas aeruginosa 1011:Haemophilus influenzae 999:Listeria monocytogenes 838: 797:Furlan–Tsai hypothesis 652:proton-pump inhibitors 531: 420:Gray platelet syndrome 183: 172: 4142:Personalized medicine 4001:Reproductive medicine 3926:Occupational medicine 3880:Evolutionary medicine 3246:Factor XII deficiency 3236:Factor VII deficiency 3054:Renal vein thrombosis 2377:(6 Pt 1): 1411–1415. 1017:Klebsiella pneumoniae 911:Platelet transfusions 836: 805:von Willebrand factor 773:Platelet transfusions 768:Platelet transfusions 529: 522:Increased destruction 335:Hereditary syndromes 178: 170: 4162:Traditional medicine 4122:Alternative medicine 3989:Addiction psychiatry 3803:Transfusion medicine 3798:Medical microbiology 3713:Gynecologic oncology 3565:Reproductive surgery 3002:Deep vein thrombosis 2897:Protein S deficiency 2887:Protein C deficiency 2325:10.1136/fn.88.5.F359 1608:10.1155/2016/3036476 1251:10.1056/NEJMra035363 795:. According to the 691:Niemann–Pick disease 265:Decreased production 214:in the forearms and 192:complete blood count 137:coagulation disorder 104:platelet transfusion 89:Complete blood count 4184:History of medicine 4167:Veterinary medicine 3974:Preventive medicine 3826:Adolescent medicine 3668:Infectious diseases 3241:Factor X deficiency 3130:May–Hegglin anomaly 2907:Prothrombin G20210A 2513:10.1136/fn.83.1.F48 685:Thrombocytapheresis 473:Stormorken syndrome 437:May–Hegglin anomaly 326:bacterial infection 4132:Molecular oncology 4089:Doctor of Medicine 4079:Master of Medicine 3996:Radiation oncology 3868:Emergency medicine 3821:Addiction medicine 3788:Clinical chemistry 3783:Clinical pathology 3575:Transplant surgery 3533:Orthopedic surgery 3511:Colorectal surgery 3367:Pulmonary hematoma 3274:Signs and symptoms 3049:Pulmonary embolism 2854:Bleeding diathesis 2742:External resources 2466:10.1007/BF00931313 2422:10.1007/BF02343233 1805:Lieber CS (2012). 1079:"Thrombocytopenia" 978:), bacteria (e.g. 839: 730:spleen enlargement 723:bone marrow biopsy 605:Medication-induced 532: 463:Sebastian syndrome 184: 173: 163:Signs and symptoms 100:immunosuppressants 4250: 4249: 4084:Master of Surgery 4048: 4047: 4033:Tropical medicine 3979:Prison healthcare 3894:Hospital medicine 3858:Disaster medicine 3848:Aviation medicine 3663:Hospital medicine 3570:Surgical oncology 3555:Pediatric surgery 3549: 3496:Endocrine surgery 3421: 3420: 3417: 3416: 3269: 3268: 3256:Dysfibrinogenemia 3140:Platelet function 3062: 3061: 2941:Purpura fulminans 2765: 2764: 2599:(12): 1122–1124. 1245:(12): 1211–1219. 1157:978-1-4963-0291-5 1041:Toxoplasma gondii 762:Lithium carbonate 734:folate deficiency 594:Gaucher's disease 458:Jacobsen syndrome 400:Filaminopathies A 361:(associated with 231:white blood cells 113: 112: 84:Diagnostic method 30:Medical condition 18:Thrombocytopaenia 16:(Redirected from 4280: 4240: 4239: 4230: 4220: 4219: 4210: 4209: 4200: 4199: 3904:Medical genetics 3889:General practice 3766:Nuclear medicine 3641:Gastroenterology 3597:Vascular surgery 3547: 3474: 3473: 3448: 3441: 3434: 3425: 3424: 3082:Thrombocytopenia 3078: 3077: 3071: 3070: 3027:Lowenberg's sign 2877:Clotting factors 2867: 2866: 2821: 2814: 2807: 2798: 2797: 2788:Thrombocytopenia 2774: 2773: 2756:Thrombocytopenia 2680: 2679: 2668: 2667: 2665: 2664: 2658: 2652:. Archived from 2635: 2625: 2619: 2618: 2608: 2584: 2578: 2577: 2541: 2535: 2534: 2524: 2492: 2486: 2485: 2448: 2442: 2441: 2404: 2395: 2394: 2366: 2347: 2346: 2336: 2319:(5): F359–F364. 2304: 2277: 2276: 2274: 2273: 2253: 2247: 2246: 2244: 2243: 2215: 2209: 2208: 2198: 2181:(983): 575–582. 2166: 2157: 2156: 2154: 2153: 2125: 2119: 2118: 2116: 2115: 2096: 2090: 2089: 2087: 2086: 2067: 2061: 2060: 2058: 2057: 2030: 2024: 2023: 2021: 2020: 2001: 1995: 1994: 1984: 1960: 1954: 1953: 1943: 1911: 1905: 1904: 1902: 1901: 1873: 1867: 1866: 1864: 1863: 1840: 1834: 1833: 1831: 1830: 1802: 1796: 1795: 1793: 1792: 1773: 1767: 1766: 1764: 1763: 1742: 1736: 1735: 1733: 1732: 1713: 1707: 1706: 1704: 1703: 1675: 1669: 1668: 1666: 1665: 1637: 1631: 1630: 1620: 1610: 1586: 1580: 1579: 1577: 1576: 1553: 1547: 1546: 1544: 1543: 1515: 1509: 1506: 1500: 1499: 1497: 1496: 1473: 1467: 1466: 1464: 1462: 1443: 1437: 1436: 1434: 1433: 1405: 1399: 1398: 1379: 1373: 1372: 1370: 1369: 1341: 1335: 1334: 1332: 1330: 1324: 1313: 1304: 1293: 1292: 1290: 1288: 1269: 1263: 1262: 1234: 1228: 1227: 1225: 1224: 1205: 1199: 1198: 1196: 1195: 1180:"Platelet count" 1176: 1170: 1169: 1143: 1137: 1136: 1134: 1133: 1105: 1099: 1098: 1096: 1094: 1075: 1005:Escherichia coli 789:hemolytic anemia 703:full blood count 384:Epstein syndrome 220:mucous membranes 121:thrombocytopenia 53: 36:Thrombocytopenia 33: 32: 21: 4288: 4287: 4283: 4282: 4281: 4279: 4278: 4277: 4273:Hematopathology 4253: 4252: 4251: 4246: 4188: 4177:Chief physician 4110: 4055: 4044: 4038:Travel medicine 4023:Sports medicine 4006:Sexual medicine 3946:Palliative care 3941:Pain management 3885:Family medicine 3863:Diving medicine 3809: 3737: 3699: 3692: 3608: 3601: 3560:Plastic surgery 3506:General surgery 3486:Cardiac surgery 3467: 3465: 3457: 3452: 3422: 3413: 3362:Hemopericardium 3312: 3265: 3196:Clotting factor 3190: 3134: 3058: 3007:Bancroft's sign 2990: 2981:Virchow's triad 2952: 2902:Factor V Leiden 2858: 2835: 2825: 2795: 2794: 2793: 2775: 2771: 2766: 2761: 2760: 2737: 2736: 2691: 2677: 2672: 2671: 2662: 2660: 2656: 2633: 2626: 2622: 2585: 2581: 2542: 2538: 2493: 2489: 2449: 2445: 2405: 2398: 2367: 2350: 2305: 2280: 2271: 2269: 2254: 2250: 2241: 2239: 2232: 2216: 2212: 2167: 2160: 2151: 2149: 2142: 2126: 2122: 2113: 2111: 2098: 2097: 2093: 2084: 2082: 2069: 2068: 2064: 2055: 2053: 2046: 2032: 2031: 2027: 2018: 2016: 2003: 2002: 1998: 1961: 1957: 1926:(4): CD011980. 1912: 1908: 1899: 1897: 1890: 1874: 1870: 1861: 1859: 1857: 1841: 1837: 1828: 1826: 1819: 1803: 1799: 1790: 1788: 1775: 1774: 1770: 1761: 1759: 1744: 1743: 1739: 1730: 1728: 1715: 1714: 1710: 1701: 1699: 1692: 1676: 1672: 1663: 1661: 1654: 1638: 1634: 1587: 1583: 1574: 1572: 1570: 1554: 1550: 1541: 1539: 1532: 1516: 1512: 1507: 1503: 1494: 1492: 1490: 1474: 1470: 1460: 1458: 1445: 1444: 1440: 1431: 1429: 1422: 1406: 1402: 1395: 1381: 1380: 1376: 1367: 1365: 1358: 1342: 1338: 1328: 1326: 1322: 1311: 1305: 1296: 1286: 1284: 1271: 1270: 1266: 1235: 1231: 1222: 1220: 1207: 1206: 1202: 1193: 1191: 1178: 1177: 1173: 1158: 1144: 1140: 1131: 1129: 1122: 1106: 1102: 1092: 1090: 1077: 1076: 1067: 1062: 1032:), fungi (e.g. 968:cytomegalovirus 948: 932: 923: 883: 877: 831: 825: 781: 770: 758:Corticosteroids 749: 716: 711:kidney function 699: 660: 647: 607: 524: 299:aplastic anemia 281: 267: 259: 227:red blood cells 210:, particularly 188:has no symptoms 165: 153:thrombocythemia 31: 28: 23: 22: 15: 12: 11: 5: 4286: 4276: 4275: 4270: 4265: 4263:Coagulopathies 4248: 4247: 4245: 4244: 4234: 4224: 4214: 4204: 4193: 4190: 4189: 4187: 4186: 4181: 4180: 4179: 4169: 4164: 4159: 4154: 4149: 4144: 4139: 4134: 4129: 4124: 4118: 4116: 4115:Related topics 4112: 4111: 4109: 4108: 4107: 4106: 4096: 4091: 4086: 4081: 4076: 4071: 4066: 4064:Medical school 4060: 4058: 4050: 4049: 4046: 4045: 4043: 4042: 4041: 4040: 4030: 4025: 4020: 4018:Sleep medicine 4015: 4014: 4013: 4003: 3998: 3993: 3992: 3991: 3981: 3976: 3971: 3965: 3960: 3959: 3958: 3948: 3943: 3938: 3933: 3928: 3923: 3922: 3921: 3911: 3906: 3901: 3896: 3891: 3882: 3877: 3876: 3875: 3865: 3860: 3855: 3850: 3845: 3844: 3843: 3838: 3831:Anesthesiology 3828: 3823: 3817: 3815: 3811: 3810: 3808: 3807: 3806: 3805: 3800: 3795: 3790: 3785: 3780: 3770: 3769: 3768: 3763: 3761:Neuroradiology 3758: 3747: 3745: 3739: 3738: 3736: 3735: 3730: 3725: 3720: 3715: 3710: 3704: 3702: 3698:Obstetrics and 3694: 3693: 3691: 3690: 3685: 3680: 3675: 3670: 3665: 3660: 3655: 3650: 3649: 3648: 3638: 3633: 3628: 3623: 3613: 3611: 3603: 3602: 3600: 3599: 3594: 3593: 3592: 3582: 3580:Trauma surgery 3577: 3572: 3567: 3562: 3557: 3552: 3551: 3550: 3543:Otolaryngology 3540: 3535: 3530: 3525: 3520: 3519: 3518: 3513: 3503: 3498: 3493: 3488: 3482: 3480: 3471: 3469:subspecialties 3459: 3458: 3451: 3450: 3443: 3436: 3428: 3419: 3418: 3415: 3414: 3412: 3411: 3410: 3409: 3401: 3400: 3399: 3394: 3389: 3387:Hemoperitoneum 3384: 3379: 3371: 3370: 3369: 3364: 3359: 3351: 3350: 3349: 3344: 3339: 3334: 3329: 3320: 3318: 3314: 3313: 3311: 3310: 3309: 3308: 3298: 3293: 3288: 3283: 3277: 3275: 3271: 3270: 3267: 3266: 3264: 3263: 3258: 3253: 3248: 3243: 3238: 3233: 3228: 3223: 3222: 3221: 3216: 3211: 3200: 3198: 3192: 3191: 3189: 3188: 3187: 3186: 3181: 3169: 3168: 3167: 3157: 3156: 3155: 3144: 3142: 3136: 3135: 3133: 3132: 3127: 3121: 3120: 3119: 3118: 3113: 3103: 3102: 3101: 3099:Evans syndrome 3086: 3084: 3075: 3068: 3064: 3063: 3060: 3059: 3057: 3056: 3051: 3046: 3045: 3044: 3039: 3034: 3032:Peabody's sign 3029: 3024: 3019: 3014: 3009: 2998: 2996: 2992: 2991: 2989: 2988: 2983: 2978: 2973: 2968: 2962: 2960: 2954: 2953: 2951: 2950: 2945: 2944: 2943: 2933: 2932: 2931: 2926: 2924:Thrombocytosis 2921: 2911: 2910: 2909: 2904: 2899: 2894: 2889: 2884: 2873: 2871: 2864: 2860: 2859: 2857: 2856: 2851: 2846: 2840: 2837: 2836: 2824: 2823: 2816: 2809: 2801: 2776: 2769: 2768: 2767: 2763: 2762: 2759: 2758: 2746: 2745: 2743: 2739: 2738: 2735: 2734: 2723: 2708: 2692: 2687: 2686: 2684: 2683:Classification 2676: 2675:External links 2673: 2670: 2669: 2620: 2579: 2552:(3): 251–256. 2536: 2507:(1): F48–F49. 2487: 2460:(3): 165–170. 2443: 2416:(2): 192–193. 2396: 2348: 2278: 2248: 2230: 2210: 2158: 2140: 2120: 2091: 2062: 2044: 2025: 1996: 1955: 1906: 1888: 1868: 1855: 1835: 1817: 1797: 1768: 1737: 1708: 1690: 1670: 1652: 1632: 1581: 1568: 1548: 1530: 1510: 1501: 1488: 1468: 1438: 1420: 1400: 1393: 1374: 1356: 1336: 1294: 1264: 1229: 1200: 1171: 1156: 1138: 1121:978-1416054764 1120: 1100: 1064: 1063: 1061: 1058: 1054:Interleukin-11 1050:breast feeding 981:Staphylococcus 947: 944: 931: 928: 922: 919: 899:blood thinners 879:Main article: 876: 873: 857:thrombopoietin 841:Many cases of 827:Main article: 824: 821: 793:plasmapheresis 780: 777: 769: 766: 748: 745: 741:megakaryocytes 714: 698: 695: 694: 693: 688: 682: 677: 672: 659: 656: 655: 654: 645: 641: 636: 631: 626: 621: 616: 606: 603: 602: 601: 596: 591: 586: 581: 576: 571: 566: 561: 556: 551: 546: 541: 523: 520: 519: 518: 517: 516: 511: 506: 501: 496: 491: 486: 480: 475: 470: 465: 460: 451: 446: 440: 434: 429: 423: 417: 412: 407: 402: 397: 395:Fanconi anemia 392: 387: 381: 376: 371: 366: 356: 351: 346: 341: 333: 328: 315: 305:thrombopoietin 301: 288: 279: 266: 263: 258: 255: 164: 161: 157:thrombocytosis 111: 110: 96: 92: 91: 86: 80: 79: 76: 72: 71: 66: 60: 59: 55: 54: 46: 45: 42: 38: 37: 29: 26: 9: 6: 4: 3: 2: 4285: 4274: 4271: 4269: 4268:Medical signs 4266: 4264: 4261: 4260: 4258: 4243: 4235: 4233: 4229: 4225: 4223: 4215: 4213: 4205: 4203: 4195: 4194: 4191: 4185: 4182: 4178: 4175: 4174: 4173: 4170: 4168: 4165: 4163: 4160: 4158: 4155: 4153: 4150: 4148: 4147:Public health 4145: 4143: 4140: 4138: 4135: 4133: 4130: 4128: 4127:Allied health 4125: 4123: 4120: 4119: 4117: 4113: 4105: 4102: 4101: 4100: 4097: 4095: 4092: 4090: 4087: 4085: 4082: 4080: 4077: 4075: 4072: 4070: 4067: 4065: 4062: 4061: 4059: 4057: 4051: 4039: 4036: 4035: 4034: 4031: 4029: 4026: 4024: 4021: 4019: 4016: 4012: 4009: 4008: 4007: 4004: 4002: 3999: 3997: 3994: 3990: 3987: 3986: 3985: 3982: 3980: 3977: 3975: 3972: 3969: 3966: 3964: 3961: 3957: 3954: 3953: 3952: 3949: 3947: 3944: 3942: 3939: 3937: 3936:Oral medicine 3934: 3932: 3931:Ophthalmology 3929: 3927: 3924: 3920: 3917: 3916: 3915: 3912: 3910: 3907: 3905: 3902: 3900: 3897: 3895: 3892: 3890: 3886: 3883: 3881: 3878: 3874: 3871: 3870: 3869: 3866: 3864: 3861: 3859: 3856: 3854: 3851: 3849: 3846: 3842: 3839: 3837: 3834: 3833: 3832: 3829: 3827: 3824: 3822: 3819: 3818: 3816: 3812: 3804: 3801: 3799: 3796: 3794: 3793:Cytopathology 3791: 3789: 3786: 3784: 3781: 3779: 3776: 3775: 3774: 3771: 3767: 3764: 3762: 3759: 3757: 3754: 3753: 3752: 3749: 3748: 3746: 3744: 3740: 3734: 3733:Urogynecology 3731: 3729: 3726: 3724: 3721: 3719: 3716: 3714: 3711: 3709: 3706: 3705: 3703: 3701: 3695: 3689: 3686: 3684: 3681: 3679: 3676: 3674: 3671: 3669: 3666: 3664: 3661: 3659: 3656: 3654: 3651: 3647: 3644: 3643: 3642: 3639: 3637: 3636:Endocrinology 3634: 3632: 3629: 3627: 3624: 3622: 3618: 3615: 3614: 3612: 3610: 3604: 3598: 3595: 3591: 3588: 3587: 3586: 3583: 3581: 3578: 3576: 3573: 3571: 3568: 3566: 3563: 3561: 3558: 3556: 3553: 3546: 3545: 3544: 3541: 3539: 3536: 3534: 3531: 3529: 3526: 3524: 3521: 3517: 3514: 3512: 3509: 3508: 3507: 3504: 3502: 3499: 3497: 3494: 3492: 3489: 3487: 3484: 3483: 3481: 3479: 3475: 3472: 3470: 3464: 3460: 3456: 3449: 3444: 3442: 3437: 3435: 3430: 3429: 3426: 3408: 3405: 3404: 3402: 3398: 3397:Hematosalpinx 3395: 3393: 3390: 3388: 3385: 3383: 3380: 3378: 3375: 3374: 3372: 3368: 3365: 3363: 3360: 3358: 3355: 3354: 3352: 3348: 3345: 3343: 3340: 3338: 3335: 3333: 3330: 3328: 3325: 3324: 3322: 3321: 3319: 3315: 3307: 3304: 3303: 3302: 3299: 3297: 3294: 3292: 3289: 3287: 3284: 3282: 3279: 3278: 3276: 3272: 3262: 3259: 3257: 3254: 3252: 3249: 3247: 3244: 3242: 3239: 3237: 3234: 3232: 3229: 3227: 3224: 3220: 3217: 3215: 3212: 3210: 3207: 3206: 3205: 3202: 3201: 3199: 3197: 3193: 3185: 3182: 3180: 3177: 3176: 3175: 3174: 3170: 3166: 3163: 3162: 3161: 3158: 3154: 3151: 3150: 3149: 3146: 3145: 3143: 3141: 3137: 3131: 3128: 3126: 3123: 3122: 3117: 3114: 3112: 3109: 3108: 3107: 3104: 3100: 3097: 3096: 3095: 3091: 3088: 3087: 3085: 3083: 3079: 3076: 3072: 3069: 3065: 3055: 3052: 3050: 3047: 3043: 3040: 3038: 3035: 3033: 3030: 3028: 3025: 3023: 3022:Louvel's sign 3020: 3018: 3017:Lisker's sign 3015: 3013: 3010: 3008: 3005: 3004: 3003: 3000: 2999: 2997: 2993: 2987: 2984: 2982: 2979: 2977: 2974: 2972: 2969: 2967: 2966:Thrombophilia 2964: 2963: 2961: 2959: 2955: 2949: 2946: 2942: 2939: 2938: 2937: 2934: 2930: 2927: 2925: 2922: 2920: 2917: 2916: 2915: 2912: 2908: 2905: 2903: 2900: 2898: 2895: 2893: 2890: 2888: 2885: 2883: 2880: 2879: 2878: 2875: 2874: 2872: 2868: 2865: 2861: 2855: 2852: 2850: 2847: 2845: 2842: 2841: 2838: 2834: 2830: 2827:Disorders of 2822: 2817: 2815: 2810: 2808: 2803: 2802: 2799: 2791: 2790: 2789: 2783: 2779: 2757: 2753: 2752: 2748: 2747: 2744: 2740: 2733: 2729: 2728: 2724: 2722: 2718: 2717: 2713: 2709: 2707: 2703: 2702: 2698: 2694: 2693: 2690: 2685: 2681: 2659:on 2011-10-03 2655: 2651: 2647: 2643: 2640:(in Polish). 2639: 2631: 2624: 2616: 2612: 2607: 2602: 2598: 2594: 2590: 2583: 2575: 2571: 2567: 2563: 2559: 2555: 2551: 2547: 2540: 2532: 2528: 2523: 2518: 2514: 2510: 2506: 2502: 2498: 2491: 2483: 2479: 2475: 2471: 2467: 2463: 2459: 2455: 2447: 2439: 2435: 2431: 2427: 2423: 2419: 2415: 2411: 2403: 2401: 2392: 2388: 2384: 2380: 2376: 2372: 2365: 2363: 2361: 2359: 2357: 2355: 2353: 2344: 2340: 2335: 2330: 2326: 2322: 2318: 2314: 2310: 2303: 2301: 2299: 2297: 2295: 2293: 2291: 2289: 2287: 2285: 2283: 2267: 2263: 2259: 2252: 2237: 2233: 2231:9780387236001 2227: 2223: 2222: 2214: 2206: 2202: 2197: 2192: 2188: 2184: 2180: 2176: 2172: 2165: 2163: 2147: 2143: 2141:9781439826423 2137: 2134:. CRC Press. 2133: 2132: 2124: 2109: 2105: 2101: 2095: 2080: 2076: 2072: 2066: 2051: 2047: 2045:9781481662420 2041: 2037: 2036: 2029: 2014: 2010: 2006: 2000: 1992: 1988: 1983: 1978: 1974: 1970: 1966: 1959: 1951: 1947: 1942: 1937: 1933: 1929: 1925: 1921: 1917: 1910: 1895: 1891: 1889:9780781784955 1885: 1881: 1880: 1872: 1858: 1856:9780080922300 1852: 1848: 1847: 1839: 1824: 1820: 1818:9781461533207 1814: 1810: 1809: 1801: 1786: 1782: 1778: 1772: 1757: 1753: 1752: 1747: 1741: 1726: 1722: 1718: 1712: 1697: 1693: 1691:9781469846224 1687: 1683: 1682: 1674: 1659: 1655: 1653:9780199229581 1649: 1645: 1644: 1636: 1628: 1624: 1619: 1614: 1609: 1604: 1600: 1596: 1592: 1585: 1571: 1569:9781139468763 1565: 1561: 1560: 1552: 1537: 1533: 1531:9780323292696 1527: 1523: 1522: 1514: 1505: 1491: 1489:9780781762274 1485: 1481: 1480: 1472: 1456: 1452: 1448: 1442: 1427: 1423: 1421:9780781765213 1417: 1413: 1412: 1404: 1396: 1394:9781582556680 1390: 1386: 1385: 1378: 1363: 1359: 1357:9780340974254 1353: 1350:. CRC Press. 1349: 1348: 1340: 1321: 1317: 1310: 1303: 1301: 1299: 1282: 1278: 1274: 1268: 1260: 1256: 1252: 1248: 1244: 1240: 1233: 1218: 1214: 1210: 1204: 1189: 1185: 1181: 1175: 1167: 1163: 1159: 1153: 1149: 1142: 1127: 1123: 1117: 1113: 1112: 1104: 1088: 1084: 1080: 1074: 1072: 1070: 1065: 1057: 1055: 1051: 1047: 1046:Gram-negative 1043: 1042: 1037: 1036: 1031: 1030: 1025: 1024: 1019: 1018: 1013: 1012: 1007: 1006: 1001: 1000: 995: 994: 989: 988: 983: 982: 977: 973: 972:rubella virus 969: 965: 961: 957: 952: 943: 941: 937: 927: 918: 916: 912: 908: 904: 900: 896: 892: 888: 882: 872: 870: 866: 862: 858: 855: 850: 848: 847:hematologists 844: 835: 830: 820: 817: 813: 810: 806: 802: 798: 794: 790: 786: 783:Treatment of 776: 774: 765: 763: 759: 755: 744: 742: 737: 735: 731: 726: 724: 720: 712: 708: 707:liver enzymes 704: 692: 689: 686: 683: 681: 678: 676: 673: 670: 666: 662: 661: 653: 649: 642: 640: 637: 635: 632: 630: 627: 625: 622: 620: 617: 615: 614:Valproic acid 612: 611: 610: 600: 597: 595: 592: 590: 587: 585: 584:Hypersplenism 582: 580: 577: 575: 572: 570: 567: 565: 562: 560: 557: 555: 552: 550: 547: 545: 542: 540: 537: 536: 535: 528: 515: 512: 510: 507: 505: 502: 500: 497: 495: 492: 490: 487: 484: 481: 479: 476: 474: 471: 469: 466: 464: 461: 459: 455: 452: 450: 447: 444: 441: 438: 435: 433: 430: 427: 424: 421: 418: 416: 413: 411: 408: 406: 403: 401: 398: 396: 393: 391: 388: 385: 382: 380: 377: 375: 372: 370: 367: 364: 360: 357: 355: 352: 350: 347: 345: 342: 340: 337: 336: 334: 332: 331:Leptospirosis 329: 327: 323: 319: 316: 314: 313:liver failure 310: 306: 302: 300: 296: 292: 289: 286: 282: 275: 272: 271: 270: 262: 254: 251: 247: 243: 238: 236: 232: 228: 223: 221: 217: 213: 209: 205: 201: 197: 193: 189: 182: 177: 169: 160: 158: 154: 150: 144: 142: 138: 134: 130: 126: 122: 118: 109: 105: 101: 97: 93: 90: 87: 85: 81: 77: 73: 70: 67: 65: 61: 56: 52: 47: 43: 39: 34: 19: 4152:Rural health 4137:Nanomedicine 3688:Rheumatology 3619: / 3538:Hand surgery 3523:Neurosurgery 3407:Hemarthrosis 3171: 3159: 3147: 3081: 3037:Pratt's sign 2849:coagulopathy 2786: 2785: 2784:profile for 2781: 2749: 2725: 2710: 2695: 2661:. Retrieved 2654:the original 2644:(1): 57–64. 2641: 2637: 2623: 2596: 2592: 2582: 2549: 2545: 2539: 2504: 2500: 2490: 2457: 2453: 2446: 2413: 2409: 2374: 2370: 2316: 2312: 2270:. Retrieved 2261: 2251: 2240:. Retrieved 2220: 2213: 2178: 2174: 2150:. Retrieved 2130: 2123: 2112:. Retrieved 2103: 2094: 2083:. Retrieved 2074: 2065: 2054:. Retrieved 2034: 2028: 2017:. Retrieved 2008: 1999: 1975:(1): 47–54. 1972: 1968: 1958: 1923: 1919: 1909: 1898:. Retrieved 1878: 1871: 1860:. Retrieved 1849:. Elsevier. 1845: 1838: 1827:. Retrieved 1807: 1800: 1789:. Retrieved 1780: 1771: 1760:. Retrieved 1749: 1740: 1729:. Retrieved 1720: 1711: 1700:. Retrieved 1680: 1673: 1662:. Retrieved 1642: 1635: 1598: 1594: 1584: 1573:. Retrieved 1558: 1551: 1540:. Retrieved 1520: 1513: 1504: 1493:. Retrieved 1478: 1471: 1459:. Retrieved 1450: 1441: 1430:. Retrieved 1410: 1403: 1383: 1377: 1366:. Retrieved 1346: 1339: 1327:. Retrieved 1315: 1285:. Retrieved 1276: 1267: 1242: 1238: 1232: 1221:. Retrieved 1212: 1203: 1192:. Retrieved 1183: 1174: 1147: 1141: 1130:. Retrieved 1110: 1103: 1091:. Retrieved 1082: 1039: 1033: 1027: 1021: 1015: 1009: 1003: 997: 991: 987:Enterococcus 985: 979: 953: 949: 933: 924: 907:fondaparinux 884: 851: 840: 803:against the 782: 771: 754:hematologist 750: 738: 727: 700: 680:Lyme disease 668: 658:Other causes 639:Panobinostat 634:Isotretinoin 619:Methotrexate 608: 589:Dengue fever 533: 268: 260: 239: 224: 198:or bleeding 185: 181:septic shock 148: 145: 120: 114: 4222:Wikiproject 4011:Venereology 3956:Neonatology 3853:Dermatology 3708:Gynaecology 3700:gynaecology 3683:Pulmonology 3501:Eye surgery 3463:Specialties 3160:aggregation 3042:Rose's sign 3012:Homans sign 2844:Coagulation 2104:www.fda.gov 1751:Mayo Clinic 1601:: 3036476. 1329:30 November 1307:Bhatia MP. 1038:spp.), and 903:bivalirudin 865:Romiplostim 859:or lead to 713:, vitamin B 624:Carboplatin 320:, systemic 274:Dehydration 41:Other names 4257:Categories 3984:Psychiatry 3970:(PM&R) 3963:Phlebology 3951:Pediatrics 3778:Anatomical 3743:Diagnostic 3723:Obstetrics 3673:Nephrology 3658:Hematology 3653:Geriatrics 3646:Hepatology 3631:Cardiology 3621:Immunology 3392:Hematocele 3357:Hemothorax 3332:Hemoptysis 3204:Hemophilia 2976:Thrombosis 2751:Patient UK 2663:2011-04-10 2371:Pediatrics 2272:2019-10-23 2242:2015-05-20 2152:2023-08-25 2114:2015-05-02 2085:2015-05-20 2056:2015-05-20 2019:2015-05-20 1900:2020-10-10 1862:2015-05-01 1829:2020-10-10 1791:2015-05-19 1762:2020-06-12 1731:2020-06-12 1702:2015-05-01 1664:2015-05-01 1575:2015-04-30 1542:2015-04-30 1495:2015-04-30 1461:4 December 1432:2015-05-01 1368:2015-05-01 1316:BTP_Report 1223:2015-05-01 1194:2015-05-01 1166:1060947164 1132:2015-04-30 1060:References 895:argatroban 889:, such as 861:thrombosis 854:endogenous 807:-cleaving 801:antibodies 629:Interferon 599:Zika virus 287:deficiency 285:folic acid 235:ecchymoses 196:nosebleeds 117:hematology 69:Hematology 4172:Physician 4056:education 3914:Neurology 3909:Narcology 3773:Pathology 3751:Radiology 3626:Angiology 3590:Andrology 3382:Hemobilia 3327:Epistaxis 2914:Platelets 1093:4 January 897:. Other " 891:lepirudin 812:ADAMTS-13 747:Treatment 697:Diagnosis 675:Snakebite 278:vitamin B 216:petechiae 125:platelets 95:Treatment 64:Specialty 4202:Category 3678:Oncology 3609:medicine 3607:Internal 3455:Medicine 3373:abdomen 3296:Petechia 3291:Hematoma 3281:Bleeding 3148:adhesion 3074:By cause 3067:Bleeding 2971:Thrombus 2870:By cause 2863:Clotting 2833:clotting 2829:bleeding 2650:12150068 2615:16371885 2574:20696142 2566:12687430 2531:10873172 2482:11251976 2438:20198866 2391:12777561 2343:12937037 2266:Archived 2236:Archived 2205:17823223 2146:Archived 2108:Archived 2079:Archived 2050:Archived 2013:Archived 1991:22314603 1950:29709077 1894:Archived 1823:Archived 1785:Archived 1756:Archived 1725:Archived 1696:Archived 1658:Archived 1627:28044112 1536:Archived 1455:Archived 1426:Archived 1362:Archived 1320:Archived 1287:5 August 1281:Archived 1259:15028825 1217:Archived 1188:Archived 1126:Archived 1087:Archived 938:and the 915:Warfarin 869:relapsed 816:proteins 809:protease 669:citrated 648:blockers 485:syndrome 291:Leukemia 208:Bruising 133:bleeding 4242:Outline 4212:Commons 4157:Therapy 4054:Medical 3617:Allergy 3585:Urology 3478:Surgery 3342:Hyphema 3317:By site 3301:Purpura 2995:By site 2778:Scholia 2732:D013921 2522:1721104 2474:3324978 2430:3569360 2334:1721612 2196:2600013 1941:5957267 1618:5164902 1035:Candida 307:by the 246:fatigue 242:malaise 212:purpura 204:periods 4232:Portal 4099:MD–PhD 3403:joint 3353:torso 3286:Bruise 3209:A/VIII 2780:has a 2648:  2613:  2572:  2564:  2529:  2519:  2480:  2472:  2436:  2428:  2389:  2341:  2331:  2228:  2203:  2193:  2138:  2042:  1989:  1948:  1938:  1886:  1853:  1815:  1688:  1650:  1625:  1615:  1566:  1528:  1486:  1418:  1391:  1354:  1257:  1164:  1154:  1118:  990:spp., 984:spp., 956:sepsis 318:Sepsis 257:Causes 250:bullae 139:among 98:None, 75:Causes 3814:Other 3323:head 2958:Clots 2782:topic 2721:287.5 2706:D69.6 2657:(PDF) 2634:(PDF) 2570:S2CID 2478:S2CID 2434:S2CID 1323:(PDF) 1312:(PDF) 322:viral 309:liver 297:, or 129:blood 3219:C/XI 3214:B/IX 2831:and 2727:MeSH 2716:9-CM 2646:PMID 2611:PMID 2562:PMID 2527:PMID 2470:PMID 2426:PMID 2387:PMID 2339:PMID 2226:ISBN 2201:PMID 2136:ISBN 2040:ISBN 1987:PMID 1946:PMID 1924:2018 1884:ISBN 1851:ISBN 1813:ISBN 1686:ISBN 1648:ISBN 1623:PMID 1599:2016 1564:ISBN 1526:ISBN 1484:ISBN 1463:2014 1416:ISBN 1389:ISBN 1352:ISBN 1331:2014 1289:2020 1255:PMID 1162:OCLC 1152:ISBN 1116:ISBN 1095:2018 905:and 665:EDTA 650:and 443:MYH9 229:and 200:gums 149:high 3548:ENT 3466:and 3111:TTP 3094:ITP 2936:DIC 2712:ICD 2697:ICD 2601:doi 2554:doi 2517:PMC 2509:doi 2462:doi 2458:241 2418:doi 2414:146 2379:doi 2375:111 2329:PMC 2321:doi 2191:PMC 2183:doi 1977:doi 1936:PMC 1928:doi 1613:PMC 1603:doi 1247:doi 1243:350 976:HIV 958:or 893:or 530:TTP 324:or 311:in 283:or 115:In 4259:: 3887:/ 3106:TM 3092:: 2754:: 2730:: 2719:: 2704:: 2701:10 2642:56 2636:. 2609:. 2597:24 2595:. 2591:. 2568:. 2560:. 2548:. 2525:. 2515:. 2505:83 2503:. 2499:. 2476:. 2468:. 2456:. 2432:. 2424:. 2412:. 2399:^ 2385:. 2373:. 2351:^ 2337:. 2327:. 2317:88 2315:. 2311:. 2281:^ 2264:. 2260:. 2234:. 2199:. 2189:. 2179:83 2177:. 2173:. 2161:^ 2144:. 2106:. 2102:. 2073:. 2048:. 2007:. 1985:. 1973:38 1971:. 1967:. 1944:. 1934:. 1922:. 1918:. 1892:. 1821:. 1779:. 1754:. 1748:. 1719:. 1694:. 1656:. 1621:. 1611:. 1597:. 1593:. 1534:. 1449:. 1424:. 1360:. 1318:. 1314:. 1297:^ 1275:. 1253:. 1241:. 1211:. 1182:. 1160:. 1124:. 1081:. 1068:^ 1026:, 1020:, 1014:, 1008:, 1002:, 996:, 974:, 970:, 909:. 863:. 756:. 732:, 715:12 709:, 705:, 293:, 280:12 276:, 244:, 119:, 106:, 102:, 3447:e 3440:t 3433:v 2820:e 2813:t 2806:v 2792:. 2714:- 2699:- 2689:D 2666:. 2617:. 2603:: 2576:. 2556:: 2550:6 2533:. 2511:: 2484:. 2464:: 2440:. 2420:: 2393:. 2381:: 2345:. 2323:: 2275:. 2245:. 2207:. 2185:: 2155:. 2117:. 2088:. 2059:. 2022:. 1993:. 1979:: 1952:. 1930:: 1903:. 1865:. 1832:. 1794:. 1765:. 1734:. 1705:. 1667:. 1629:. 1605:: 1578:. 1545:. 1498:. 1465:. 1435:. 1397:. 1371:. 1333:. 1291:. 1261:. 1249:: 1226:. 1197:. 1168:. 1135:. 1097:. 646:2 644:H 456:/ 365:) 20:)

Index

Thrombocytopaenia

Specialty
Hematology
Diagnostic method
Complete blood count
immunosuppressants
platelet transfusion
surgical removal of the spleen
hematology
platelets
blood
bleeding
coagulation disorder
intensive care patients
thrombocythemia
thrombocytosis


septic shock
has no symptoms
complete blood count
nosebleeds
gums
periods
Bruising
purpura
petechiae
mucous membranes
red blood cells

Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.

↑