497:
356:
31:
405:, and tetanus. This acellular vaccine is safer than the previously used DTP with whole inactivated pertussis (now retroactively notated DTwP). Another option is DT, which is a combination of diphtheria and tetanus vaccines. This is given as an alternative to infants who have conflicts with the DTaP vaccine. Quadrivalent, pentavalent, and hexavalent formulations contain DTaP with one or more of the additional vaccines: inactivated
3110:
1635:
1595:
1552:
1428:
1375:
1288:
1249:
1177:
964:
925:
874:
801:
712:
439:(WHO) recommends six doses in childhood starting at six weeks of age. Four doses of DTaP are to be given in early childhood. The first dose should be around two months of age, the second at four months, the third at six, and the fourth from fifteen to eighteen months of age. There is a recommended fifth dose to be administered to four- to six-year-olds.
577:) was first used in 1948, and was continued until 1991, when it was replaced with an acellular form of the pertussis vaccine due to safety concerns. Half of those who received the DT(w)P vaccine had redness, swelling, and pain around the injection site, which convinced researchers to find a replacement vaccine.
363:
Vaccination confers near-complete protection from tetanus, provided the individual has received their recommended booster shots. Globally, deaths from tetanus in newborns decreased from 787,000 in 1988 to 58,000 in 2010, and 34,000 deaths in 2015 (a 96% decrease from 1988). In the 1940s, before the
504:
Common side effects of the tetanus vaccine include fever, redness, and swelling with soreness or tenderness around the injection site (one in five people have redness or swelling). Body aches and tiredness have been reported following Tdap. Td / Tdap can cause painful swelling of the entire arm in
380:
during each pregnancy, preferably between weeks 27 and 36, to allow antibody transfer to the fetus. All postpartum women who have not previously received the Tdap vaccine are recommended to get it prior to discharge after delivery. It is recommended for pregnant women who have never received the
488:(ACIP) recommended that either tetanus and diphtheria toxoids (Td) vaccine or Tdap to be used for the decennial Td booster, tetanus prevention during wound management, and for additional required doses in the catch-up immunization schedule if a person has received at least one Tdap dose.
364:
vaccine, there were about 550 cases of tetanus per year in the United States, which has decreased to about 30 cases per year in the 2000s. Nearly all cases are among those who have never received a vaccine, or adults who have not stayed up to date on their 10-year booster shots.
442:
Td and Tdap are for older children, adolescents, and adults and can be injected into the deltoid muscle. These are boosters and are recommended every ten years. It is safe to have shorter intervals between a single dose of Tdap and a dose of the Td booster.
1496:
The Safety of
Immunizing with Tetanus–diphtheria–acellular Pertussis Vaccine (Tdap) Less than 2 Years following Previous Tetanus Vaccination: Experience during a Mass Vaccination Campaign of Healthcare Personnel during a Respiratory Illness
580:
Two new vaccines were launched in 1992. These combined tetanus and diphtheria with acellular pertussis (TDaP or DTaP), which could be given to adolescents and adults (as opposed to previously when the vaccine was only given to children).
280:
After three doses, almost everyone is initially immune, but additional doses every ten years are recommended to maintain immunity. A booster shot should be given within 48 hours of an injury to people whose immunization is out of date.
469:
Tdap is given as a one-time, first-time-only dose that includes the tetanus, diphtheria, and acellular pertussis vaccinations. This should not be administered to those who are under the age of eleven or over the age of sixty-five.
326:
and tetanus vaccines. DTaP and DT are given to children less than seven years old, while Tdap and Td are given to those seven years old and older. The lowercase d and p denote lower strengths of diphtheria and pertussis vaccines.
598:
381:
tetanus vaccine (i.e., neither DTP or DTaP, nor DT as a child or Td or TT as an adult) to receive a series of three Td vaccinations starting during pregnancy to ensure protection against maternal and
766:"Updated recommendations for use of tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine (Tdap) in pregnant women--Advisory Committee on Immunization Practices (ACIP), 2012"
428:
Because DTaP and DT are administered to children less than a year old, the recommended location for injection is the anterolateral thigh muscle. However, these vaccines can be injected into the
1447:"Combined hexavalent diphtheria-tetanus-acellular pertussis-hepatitis B-inactivated poliovirus-Haemophilus influenzae type B vaccine; Infanrix™ hexa: twelve years of experience in Italy"
1394:"Licensure of a diphtheria and tetanus toxoids and acellular pertussis adsorbed, inactivated poliovirus, and haemophilus B conjugate vaccine and guidance for use in infants and children"
455:
production (antibodies) is not at a constant high rate of activity. This is because after the introduction of the vaccine when lymphocyte production is high, the production activity of
831:"Use of Tetanus Toxoid, Reduced Diphtheria Toxoid, and Acellular Pertussis Vaccines: Updated Recommendations of the Advisory Committee on Immunization Practices - United States, 2019"
3150:
385:. In such cases, Tdap is recommended to be substituted for one dose of Td, again preferably between 27 and 36 weeks of gestation, and then the series completed with Td.
334:
was developed in 1890, with its protective effects lasting a few weeks. The tetanus toxoid vaccine was developed in 1924, and came into common use for soldiers in
1685:"Prevention of Pertussis, Tetanus, and Diphtheria with Vaccines in the United States: Recommendations of the Advisory Committee on Immunization Practices (ACIP)"
1570:"Update: vaccine side effects, adverse reactions, contraindications, and precautions. Recommendations of the Advisory Committee on Immunization Practices (ACIP)"
299:
Redness and pain at the site of injection occur in between 25% and 85% of people. Fever, feeling tired, and minor muscle pain occurs in less than 10% of people.
1357:
737:
134:
1963:
241:
3013:
2161:
2050:
1159:
1071:
The selection and use of essential medicines 2023: web annex A: World Health
Organization model list of essential medicines: 23rd list (2023)
2201:
2196:
1537:
485:
466:
Td and Tdap are the booster shots given every ten years to maintain immunity for adults nineteen years of age to sixty-five years of age.
1052:
1914:
1899:
1883:
1861:
1842:
1616:
1531:
1353:
1271:
1230:
1136:
947:
906:
701:
481:
910:
705:
1267:"Pregnancy Guidelines and Recommendations by Vaccine - Tetanus, Diphtheria, and Pertussis (Tdap); & Tetanus and Diphtheria (Td)"
1821:
1656:
1413:
2593:
2382:
1620:
561:
version of the vaccine, created in 1938, was proven to be successful when it was used to prevent tetanus in the military during
2211:
1142:
Epidemiology and
Prevention of Vaccine-Preventable Diseases (CDC, Epidemiology and Prevention of Vaccine-Preventable Diseases)
3064:
2992:
1153:
339:
2598:
1953:
248:
284:
Confirming that pregnant women are up to date on tetanus immunization during each pregnancy can prevent both maternal and
2630:
2387:
2313:
2166:
1234:
1993:
3040:
2352:
1985:
373:
644:
2452:
1806:
1046:
1019:
992:
1346:
729:
3081:
3019:
1994:
111:
2640:
2608:
2603:
2437:
164:
92:
1943:
549:
The first vaccine for passive immunology was discovered by a group of German scientists under the leadership of
2698:
2308:
1817:
477:. However, Td has less of the diphtheria toxoid, which is why the "d" is lowercase and the "T" is capitalized.
2496:
2206:
410:
1266:
943:"Recommended Child and Adolescent Immunization Schedule for ages 18 years or younger, United States, 2020"
3100:
2618:
2060:
2043:
942:
1933:
2668:
1909:
1788:
1203:
1194:
1066:
640:
473:
Td is the booster shot given to people over the age of seven and includes the tetanus and diphtheria
436:
1851:
3140:
3135:
2623:
2588:
2583:
2578:
1957:
1947:
1937:
1927:
1140:
3069:
3002:
2983:
2779:
2751:
2713:
2708:
2688:
2216:
1094:
122:
1893:
1525:
1307:"Choosing from Whole Cell and Acellular Pertussis Vaccines-Dilemma for the Developing Countries"
533:. This is beneficial because it means that if the disease is ever introduced into the body, the
3050:
2979:
1978:
1877:
1036:
1009:
3045:
2879:
2874:
2330:
2276:
2186:
1738:
1684:
982:
830:
1737:
Kahn KE, Black CL, Ding H, Williams WW, Lu PJ, Fiebelkorn AP, et al. (September 2018).
599:"Active substance: diphtheria / tetanus vaccines (adsorbed), diphtheria vaccines (adsorbed)"
2928:
2869:
2660:
2303:
2181:
2132:
2099:
2033:
1683:
Liang JL, Tiwari T, Moro P, Messonnier NE, Reingold A, Sawyer M, et al. (April 2018).
1198:
902:
212:
1923:
1832:
1739:"Influenza and Tdap Vaccination Coverage Among Pregnant Women - United States, April 2018"
1612:
695:
505:
one of 500 people. Tetanus toxoid containing vaccines (DTaP, DTP, Tdap, Td, DT) may cause
8:
2851:
2817:
2703:
2526:
2469:
2464:
2415:
2246:
2114:
2086:
2038:
1393:
203:
2521:
2266:
1836:
1652:
525:
is generated when a dead or weakened version of the disease enters the body, causing an
2884:
2718:
2459:
2425:
2410:
2286:
2271:
2256:
2176:
2094:
1766:
1720:
1471:
1446:
1323:
1306:
858:
785:
522:
323:
315:
277:. During childhood, five doses are recommended, with a sixth given during adolescence.
420:
For the every ten-year booster Td or Tdap may be used, though Tdap is more expensive.
3145:
3007:
2974:
2807:
2648:
2538:
2432:
2293:
2118:
2081:
1971:
1802:
1771:
1725:
1707:
1584:
1476:
1405:
1347:"2016 Binational Immunization Resource Tool for Children from Birth Through 18 Years"
1328:
1149:
1042:
1015:
988:
863:
790:
669:
506:
456:
319:
179:
84:
2953:
1445:
Baldo V, Bonanni P, Castro M, Gabutti G, Franco E, Marchetti F, et al. (2014).
3130:
2933:
2918:
2774:
2635:
2548:
1792:
1761:
1753:
1715:
1699:
1466:
1458:
1318:
1074:
853:
845:
780:
659:
550:
496:
382:
285:
147:
2474:
3114:
2938:
2736:
2543:
2501:
2392:
2342:
2251:
2241:
2171:
2110:
2106:
2055:
1855:
526:
518:
1011:
Pharmacology for
Student and Pupil Nurses and Students in Associated Professions
397:
vaccine, which is three inactive toxins in one injection. DTaP protects against
22:
3075:
2802:
2693:
2653:
2533:
2359:
2298:
1785:
The immunological basis for immunization series: module 3: tetanus: update 2018
1226:
554:
460:
429:
463:
means that there must be a booster to help keep the white blood cells active.
355:
3124:
2958:
2943:
2913:
2908:
2763:
2516:
2511:
2420:
2065:
1711:
1639:
1599:
1569:
1556:
1432:
1379:
1292:
1253:
1181:
968:
929:
878:
805:
765:
716:
534:
30:
2320:
1391:
763:
3035:
2678:
2573:
2506:
2447:
2127:
2018:
1998:
1775:
1757:
1729:
1703:
1480:
1409:
1332:
867:
849:
794:
673:
562:
377:
335:
142:
1588:
1135:
338:. Its use resulted in a 95% decrease in the rate of tetanus. It is on the
2822:
2812:
2673:
2479:
2367:
2335:
2261:
2123:
2014:
2006:
566:
414:
300:
78:
36:
1797:
1079:
664:
2948:
2923:
2613:
2563:
570:
558:
530:
452:
398:
223:
61:
1038:
Introduction to
Epidemiology: Distribution and Determinants of Disease
306:
A number of vaccine combinations include the tetanus vaccine, such as
2997:
2568:
2441:
2010:
1894:"DTaP (Diphtheria, Tetanus, Pertussis) Vaccine Information Statement"
1526:"Tdap (Tetanus, Diphtheria, Pertussis) Vaccine Information Statement"
1462:
574:
402:
393:
The first vaccine is given in infancy. The baby is injected with the
331:
289:
829:
Havers FP, Moro PL, Hunter P, Hariri S, Bernstein H (January 2020).
694:
Hamborsky J, Kroger A, Wolfe S, eds. (2015). "Chapter 21: Tetanus".
2839:
2832:
2827:
2797:
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2489:
2484:
293:
106:
1831:
Hall E, Wodi AP, Hamborsky J, Morelli V, Schillie S, eds. (2021).
2558:
2002:
1638:
This article incorporates text from this source, which is in the
1598:
This article incorporates text from this source, which is in the
1555:
This article incorporates text from this source, which is in the
1431:
This article incorporates text from this source, which is in the
1378:
This article incorporates text from this source, which is in the
1291:
This article incorporates text from this source, which is in the
1252:
This article incorporates text from this source, which is in the
1180:
This article incorporates text from this source, which is in the
967:
This article incorporates text from this source, which is in the
928:
This article incorporates text from this source, which is in the
877:
This article incorporates text from this source, which is in the
804:
This article incorporates text from this source, which is in the
715:
This article incorporates text from this source, which is in the
538:
274:
54:
44:
2861:
2846:
2137:
474:
270:
66:
764:
Centers for
Disease Control Prevention (CDC) (February 2013).
517:
The type of vaccination for this disease is called artificial
2856:
2741:
2347:
2281:
1392:
Centers for
Disease Control Prevention (CDC) (October 2008).
406:
359:
Decrease in tetanus deaths by age group between 1990 and 2017
2156:
1857:
Manual for the surveillance of vaccine-preventable diseases
1838:
Epidemiology and
Prevention of Vaccine-Preventable Diseases
1653:"Whooping Cough: Vaccine Combined with Tetanus, Diphtheria"
697:
Epidemiology and
Prevention of Vaccine-Preventable Diseases
394:
311:
307:
984:
35:
Tetanus vaccination is often administered via combination
1782:
1682:
1444:
1193:
1065:
639:
3151:
World Health Organization essential medicines (vaccines)
1878:"Td (Tetanus, Diphtheria) Vaccine Information Statement"
1830:
509:
at a rate of one out of every 100,000 to 200,000 doses.
417:, with the availability varying in different countries.
340:
World Health Organization's List of Essential Medicines
828:
645:"Tetanus vaccines: WHO position paper – February 2017"
557:
was discovered and produced in 1924. A more effective
459:
will start to decline. The decline in activity of the
3098:
1736:
693:
3014:Cedillo v. Secretary of Health and Human Services
500:A bump resulting from a tetanus vaccine injection
3122:
1850:Roush SW, Baldy LM, Hall MA, eds. (March 2019).
606:List of nationally authorised medicinal products
376:specify that women should receive a dose of the
1954:Diphtheria-Tetanus-acellular Pertussis Vaccines
1131:
1129:
1127:
1125:
1123:
1121:
1119:
1117:
1115:
211:
1849:
1148:. Washington, D.C.: Public Health Foundation.
824:
822:
820:
818:
816:
814:
1979:
980:
608:. European Medicines Agency. 14 January 2021.
288:. The vaccine is very safe, including during
1438:
1112:
486:Advisory Committee on Immunization Practices
110:
1910:"DTaP/Tdap/Td ACIP Vaccine Recommendations"
1503:
1487:
1298:
811:
303:occur in fewer than one in 100,000 people.
1986:
1972:
1915:Centers for Disease Control and Prevention
1900:Centers for Disease Control and Prevention
1884:Centers for Disease Control and Prevention
1862:Centers for Disease Control and Prevention
1843:Centers for Disease Control and Prevention
1617:Centers for Disease Control and Prevention
1532:Centers for Disease Control and Prevention
1354:Centers for Disease Control and Prevention
1272:Centers for Disease Control and Prevention
1231:Centers for Disease Control and Prevention
1137:Centers for Disease Control and Prevention
948:Centers for Disease Control and Prevention
907:Centers for Disease Control and Prevention
702:Centers for Disease Control and Prevention
689:
687:
685:
683:
635:
482:Centers for Disease Control and Prevention
29:
1956:at the U.S. National Library of Medicine
1946:at the U.S. National Library of Medicine
1936:at the U.S. National Library of Medicine
1926:at the U.S. National Library of Medicine
1796:
1765:
1719:
1470:
1322:
1078:
897:
895:
893:
891:
889:
887:
857:
784:
759:
757:
755:
663:
633:
631:
629:
627:
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623:
621:
619:
617:
615:
1509:
1259:
495:
354:
1841:(14th ed.). Washington D.C.: U.S.
1823:Immunisation against infectious disease
1059:
680:
83:
3123:
1815:
1493:
1034:
884:
752:
612:
512:
185:
1967:
1623:from the original on 22 December 2011
1540:from the original on 28 December 2019
1363:from the original on 11 February 2017
1237:from the original on 11 November 2014
1073:. Geneva: World Health Organization.
1007:
913:from the original on 12 February 2015
903:"Vaccines: VPD-VAC/Tetanus/main page"
541:and produce antibodies more rapidly.
173:
101:
1944:Diphtheria-Tetanus-Pertussis Vaccine
1416:from the original on 7 November 2016
1304:
740:from the original on 8 December 2015
451:Booster shots are important because
146:
1605:
708:from the original on 13 April 2017.
569:(which is the combined vaccine for
446:
13:
3041:Eradication of infectious diseases
2798:Androvax (androstenedione albumin)
1783:World Health Organization (2018).
1675:
1055:from the original on 5 March 2016.
374:prenatal care in the United States
14:
3162:
2631:Respiratory syncytial virus (RSV)
1870:
1816:Ramsay M, ed. (21 January 2021).
1165:from the original on 6 March 2008
1041:. Nelson Education. p. 251.
529:which includes the production of
388:
3108:
3020:Alternative vaccination schedule
1995:Artificial induction of immunity
1659:from the original on 6 June 2017
1633:
1593:
1550:
1426:
1373:
1311:Iranian Journal of Public Health
1286:
1247:
1175:
962:
923:
872:
799:
710:
350:
16:Vaccines used to prevent tetanus
1811:. License: CC BY-NC-SA 3.0 IGO.
1645:
1583:(RR-12): 1–35. September 1996.
1562:
1518:
1512:Tetanus: Important New Concepts
1385:
1339:
1219:
1187:
1087:
1028:
1001:
491:
345:
322:, and DT and Td, which contain
2852:Ovandrotone albumin (Fecundin)
1613:"Vaccines & Immunizations"
974:
935:
722:
591:
1:
2388:Group B streptococcal disease
2207:Vaccines for Children Program
1514:. Amsterdam: Excerpta Medica.
1095:"Deaths from tetanus, by age"
652:Weekly Epidemiological Record
584:
411:Haemophilus influenzae type b
1746:MMWR Morb. Mortal. Wkly. Rep
1398:MMWR Morb. Mortal. Wkly. Rep
981:Gradmann C, Simon J (2010).
838:MMWR Morb. Mortal. Wkly. Rep
773:MMWR Morb. Mortal. Wkly. Rep
730:"Puncture wounds: First aid"
553:in 1890. The first inactive
367:
7:
423:
10:
3167:
1934:Diphtheria-Tetanus Vaccine
1083:. WHO/MHP/HPS/EML/2023.02.
544:
3059:
3028:
2967:
2899:
2790:
2762:
2729:
2403:
2234:
2227:
2146:
2074:
2026:
1789:World Health Organization
1305:Syed MA (February 2017).
1204:World Health Organization
1195:World Health Organization
1067:World Health Organization
1014:. Elsevier. p. 162.
641:World Health Organization
437:World Health Organization
301:Severe allergic reactions
238:
222:
202:
197:
163:
158:
133:
121:
91:
77:
72:
60:
50:
43:
28:
2383:Clostridioides difficile
1958:Medical Subject Headings
1948:Medical Subject Headings
1938:Medical Subject Headings
1928:Medical Subject Headings
1826:. Public Health England.
987:. Springer. p. 53.
273:vaccine used to prevent
2641:Tick-borne encephalitis
3051:List of vaccine topics
2051:Mathematical modelling
1758:10.15585/mmwr.mm6738a3
1704:10.15585/mmwr.rr6702a1
850:10.15585/mmwr.mm6903a5
501:
360:
3046:Vaccinate Your Family
2497:Japanese encephalitis
1852:"Chapter 16: Tetanus"
1833:"Chapter 21: Tetanus"
1818:"Chapter 30: Tetanus"
1451:Hum Vaccin Immunother
499:
409:virus vaccine (IPV),
358:
2929:John Franklin Enders
2115:Virus-like particle
2039:Vaccine ingredients
1860:. Atlanta GA: U.S.
1510:Veronesi R (1981).
1139:(2011). "Tetanus".
736:. 4 February 2015.
537:will recognize the
513:Mechanism of action
45:Vaccine description
25:
3086:Never to phase III
2885:Hexavalent vaccine
2699:Epstein–Barr virus
2594:Oxford–AstraZeneca
2287:NmVac4-A/C/Y/W-135
1919:. 28 January 2020.
1499:. pp. 8001–7.
1494:Talbot EA (2010).
502:
361:
320:pertussis vaccines
292:and in those with
21:
3096:
3095:
3008:Vaccines and SIDS
2895:
2894:
2669:Hepatitis A and B
2645:Varicella zoster
2107:Subunit/component
1752:(38): 1055–1059.
1155:978-0-01-706609-1
1099:Our World in Data
1035:Macera C (2012).
1008:Jones BR (2016).
952:. 3 February 2020
700:(13th ed.).
643:(February 2017).
507:brachial neuritis
457:white blood cells
256:
255:
189:
177:
104:
3158:
3113:
3112:
3111:
3104:
2987:MMR autism fraud
2934:Maurice Hilleman
2919:Hilary Koprowski
2232:
2231:
1988:
1981:
1974:
1965:
1964:
1920:
1905:
1889:
1865:
1846:
1827:
1812:
1800:
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1743:
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1723:
1689:
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1609:
1603:
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1553:
1549:
1547:
1545:
1522:
1516:
1515:
1507:
1501:
1500:
1491:
1485:
1484:
1474:
1463:10.4161/hv.26269
1442:
1436:
1430:
1429:
1425:
1423:
1421:
1389:
1383:
1377:
1376:
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1351:
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1337:
1336:
1326:
1302:
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667:
649:
637:
610:
609:
603:
595:
551:Emil von Behring
480:In 2020, the US
447:Additional doses
383:neonatal tetanus
314:, which contain
286:neonatal tetanus
261:, also known as
252:
251:
244:
215:
187:
184:
175:
172:
150:
114:
103:
100:
87:
33:
26:
24:
20:
3166:
3165:
3161:
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3159:
3157:
3156:
3155:
3141:Toxoid vaccines
3136:1924 in biology
3121:
3120:
3119:
3109:
3107:
3099:
3097:
3092:
3091:
3076:Clinical trials
3055:
3024:
2963:
2939:Stanley Plotkin
2901:
2891:
2803:Cancer vaccines
2786:
2780:Schistosomiasis
2758:
2752:Trypanosomiasis
2725:
2689:Cytomegalovirus
2599:Pfizer–BioNTech
2399:
2223:
2172:Vaccine wastage
2142:
2070:
2022:
1992:
1908:
1892:
1876:
1873:
1868:
1809:
1741:
1692:MMWR Recomm Rep
1687:
1678:
1676:Further reading
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1577:MMWR Recomm Rep
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1568:
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1541:
1536:. August 2021.
1524:
1523:
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1404:(39): 1079–80.
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1227:"About Tetanus"
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573:, tetanus, and
547:
527:immune response
521:. This type of
519:active immunity
515:
494:
449:
426:
391:
370:
353:
348:
318:, tetanus, and
259:Tetanus vaccine
247:
245:
242:(what is this?)
239:
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124:
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39:
23:Tetanus vaccine
17:
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5:
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2609:Sinopharm BIBP
2606:
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2559:Bharat Biotech
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2209:
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2199:
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2189:
2187:Vaccine injury
2184:
2179:
2174:
2169:
2164:
2159:
2150:
2148:
2147:Administration
2144:
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2024:
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1991:
1990:
1983:
1976:
1968:
1962:
1961:
1951:
1941:
1931:
1924:Tetanus Toxoid
1921:
1906:
1904:. August 2021.
1890:
1888:. August 2021.
1872:
1871:External links
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461:T-helper cells
448:
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432:if necessary.
430:deltoid muscle
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389:Specific types
387:
372:Guidelines on
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2944:H. Fred Clark
2942:
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2914:Louis Pasteur
2912:
2910:
2909:Edward Jenner
2907:
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2898:
2886:
2883:
2881:
2880:DTwP-HepB-Hib
2878:
2876:
2875:DTaP-IPV-HepB
2873:
2871:
2868:
2867:
2866:combination:
2865:
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2574:EpiVacCorona
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2272:Lyme disease
2100:Heterologous
1999:Immunization
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1418:. Retrieved
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1365:. Retrieved
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1300:
1278:. Retrieved
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1239:. Retrieved
1221:
1209:. Retrieved
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1189:
1167:. Retrieved
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1102:. Retrieved
1098:
1089:
1080:10665/371090
1070:
1061:
1037:
1030:
1010:
1003:
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976:
954:. Retrieved
946:
937:
915:. Retrieved
844:(3): 77–83.
841:
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779:(7): 131–5.
776:
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742:. Retrieved
733:
724:
696:
665:10665/254583
658:(6): 53–76.
655:
651:
605:
593:
579:
563:World War II
548:
516:
503:
492:Side effects
479:
472:
468:
465:
450:
441:
434:
427:
419:
392:
378:Tdap vaccine
371:
362:
346:Medical uses
336:World War II
329:
305:
298:
283:
279:
266:
262:
258:
257:
246:
240:
165:Legal status
159:Legal status
93:License data
62:Vaccine type
37:DPT vaccines
18:
3072:from market
2968:Controversy
2902:researchers
2818:Hepatitis B
2704:Hepatitis C
2649:Chicken pox
2475:Hepatitis E
2470:Hepatitis B
2465:Hepatitis A
2416:Chikungunya
2393:Shigellosis
2247:Brucellosis
2133:Therapeutic
2087:Inactivated
2027:Development
2015:Inoculation
2007:Vaccination
1698:(2): 1–44.
1627:27 November
1544:28 December
1420:22 December
1367:22 December
1241:11 December
917:10 February
734:Mayo Clinic
415:Hepatitis B
413:conjugate,
198:Identifiers
79:MedlinePlus
3125:Categories
3003:Thiomersal
2949:Paul Offit
2924:Jonas Salk
2900:Inventors/
2771:research:
2748:research:
2685:research:
2614:Skycovione
2604:Sanofi–GSK
2549:SARS-CoV-2
2460:Hantavirus
2426:rVSV-ZEBOV
2411:Adenovirus
2379:research:
2257:Diphtheria
2095:Attenuated
1280:15 January
1211:12 January
1104:13 January
956:6 February
744:6 December
585:References
571:diphtheria
531:antibodies
453:lymphocyte
399:diphtheria
324:diphtheria
316:diphtheria
224:ChemSpider
213:93384-51-1
204:CAS Number
3082:Phase III
3070:Withdrawn
2998:Pox party
2808:ALVAC-CEA
2730:Protozoan
2619:Sputnik V
2569:CoronaVac
2539:Rotavirus
2442:Pandemrix
2294:Pertussis
2235:Bacterial
2119:Synthetic
2082:Conjugate
2034:Adjuvants
2011:Infection
1712:1057-5987
1199:"Tetanus"
1169:4 January
575:pertussis
403:pertussis
368:Pregnancy
332:antiserum
290:pregnancy
129:Injection
123:Routes of
3146:Vaccines
3115:Medicine
2840:Prostvac
2833:Gardasil
2828:Cervarix
2775:Hookworm
2654:Shingles
2636:Smallpox
2554:Corbevax
2490:Gardasil
2485:Cervarix
2228:Vaccines
2182:Schedule
2153:Global:
2061:Timeline
2003:Vaccines
1776:30260946
1730:29702631
1657:Archived
1621:Archived
1538:Archived
1497:Outbreak
1481:24004825
1414:Archived
1410:18830213
1358:Archived
1333:28451568
1235:Archived
1160:Archived
1069:(2023).
1053:Archived
911:Archived
868:31971933
795:23425962
738:Archived
706:Archived
674:28185446
567:DTP/DTwP
559:adsorbed
523:immunity
424:Schedule
330:Tetanus
294:HIV/AIDS
269:), is a
249:(verify)
135:ATC code
107:DailyMed
3131:Tetanus
3029:Related
2975:General
2737:Malaria
2624:Valneva
2589:Novavax
2584:Moderna
2579:Janssen
2564:CanSino
2544:Rubella
2502:Measles
2373:Td/Tdap
2343:Typhoid
2326:Tetanus
2321:Q fever
2252:Cholera
2242:Anthrax
2111:Peptide
2075:Classes
2056:Storage
1791:(WHO).
1767:6188122
1721:5919600
1619:(CDC).
1615:. U.S.
1589:8801442
1472:4181021
1356:(CDC).
1324:5402791
1233:(CDC).
909:(CDC).
859:7367039
786:4604886
704:(CDC).
545:History
539:antigen
475:toxoids
275:tetanus
151:)
145: (
143:J07AM01
112:Tetanus
109::
85:a682198
55:Tetanus
3101:Portal
3065:WHO-EM
2985:Lancet
2862:TA-NIC
2847:NicVAX
2694:Dengue
2534:Rabies
2360:Typhus
2299:Plague
2177:Policy
2138:Toxoid
2066:Trials
1960:(MeSH)
1950:(MeSH)
1940:(MeSH)
1930:(MeSH)
1864:(CDC).
1845:(CDC).
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271:toxoid
180:â„ž-only
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2993:NCVIA
2857:TA-CD
2791:Other
2742:RTS,S
2522:Sabin
2517:Polio
2512:Mumps
2421:Ebola
2404:Viral
2353:ViCPS
2348:Ty21a
2282:MeNZB
2212:VAERS
2162:NITAG
2091:Live
1917:(CDC)
1902:(CDC)
1898:U.S.
1886:(CDC)
1882:U.S.
1742:(PDF)
1688:(PDF)
1663:1 May
1573:(PDF)
1534:(CDC)
1530:U.S.
1361:(PDF)
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1274:(CDC)
1206:(WHO)
1163:(PDF)
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950:(CDC)
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769:(PDF)
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602:(PDF)
407:polio
2719:Zika
2679:MMRV
2527:Salk
2507:Mpox
2453:LAIV
2448:H5N1
2438:H1N1
2314:PPSV
2197:ACIP
2193:US:
2167:SAGE
2128:mRNA
2044:list
1803:ISBN
1772:PMID
1726:PMID
1708:ISSN
1665:2017
1629:2011
1585:PMID
1546:2019
1477:PMID
1422:2016
1406:PMID
1369:2016
1329:PMID
1282:2020
1243:2014
1213:2020
1171:2016
1150:ISBN
1106:2020
1043:ISBN
1016:ISBN
989:ISBN
958:2020
919:2015
864:PMID
791:PMID
746:2015
670:PMID
435:The
395:DTaP
312:Tdap
310:and
308:DTaP
231:none
2980:MMR
2823:HPV
2813:BCG
2714:HIV
2674:MMR
2480:HPV
2433:Flu
2336:BCG
2309:PCV
2262:Hib
2217:VSD
2124:DNA
2019:J07
1793:hdl
1762:PMC
1754:doi
1716:PMC
1700:doi
1467:PMC
1459:doi
1319:PMC
1075:hdl
854:PMC
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781:PMC
660:hdl
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