31:
773:
758:
471:
3090:
3118:
717:
for 14 days can also be used for this. The advantage of tafenoquine is that it has a long half-life (2–3 weeks) and therefore a single treatment is sufficient. For this use, a single dose of 300 mg is recommended. It is used with another medication, such as
1175:
Elmes NJ, Nasveld PE, Kitchener SJ, Kocisko DA, Edstein MD (November 2008). "The efficacy and tolerability of three different regimens of tafenoquine versus primaquine for post-exposure prophylaxis of
Plasmodium vivax malaria in the Southwest Pacific".
226:
689:
Tafenoquine may be used to prevent all types of malaria. For this use 200 mg 3 days before travel then 200 mg per week until one week after travel is recommended.
550:
1380:
1573:
1654:
592:
InChI=1S/C24H28F3N3O3/c1-14-11-20(32-4)30-22-18(29-15(2)7-6-10-28)13-19(31-3)23(21(14)22)33-17-9-5-8-16(12-17)24(25,26)27/h5,8-9,11-13,15,29H,6-7,10,28H2,1-4H3
181:
1539:
1505:
1453:
608:
669:
is unclear but it is effective both in the liver and bloodstream. A possible mechanism of action and other novel perspectives have been published.
3027:
1595:
69:
1731:
654:
564:
1647:
1151:
1212:"Conclusions and Recommendations from the Fifteenth Meeting of the WHO Advisory Committee on Safety of Medicinal Products (ACSoMP)"
2495:
3020:
1146:
1640:
1632:
2319:
1454:"Kozenis (tafenoquine) approved by the Australian Therapeutic Goods Administration for the radical cure of P. vivax malaria"
1368:
3143:
2637:
2410:
1561:
3163:
1346:
1211:
615:
120:
3034:
1962:
584:
3041:
2336:
713:
that is responsible for relapse of these malarial infections, even when the blood stages are successfully cleared.
672:
Tafenoquine was approved for medical use in
Australia and in the United States in 2018. Tafenoquine is related to
3058:
2967:
1527:
1493:
1404:"Tafenoquine receives regulatory approval in USA for prophylaxis of malaria and radical cure of Plasmodium vivax"
794:
Tafenoquine was approved for medical use in
Australia and in the United States in 2018. Tafenoquine was given an
257:
211:
101:
729:
parasites that are now known to occur in the spleen, bone marrow, and possibly elsewhere in chronic infections.
3013:
2191:
2375:
1755:
3138:
1567:
1533:
1499:
1374:
1341:
342:
2555:
943:"Guidance for Using Tafenoquine for Prevention and Antirelapse Therapy for Malaria - United States, 2019"
450:
419:
3108:
1003:
79:
2732:
2035:
725:
There is a need to determine whether or not tafenoquine kills the numerous, non-circulating asexual
466:
3069:
2962:
2736:
2619:
2515:
2505:
2405:
636:. With respect to acute malaria, it is used together with other medications to prevent relapse by
439:
2500:
2324:
2186:
2163:
1930:
157:
51:
3168:
3153:
2786:
2575:
2545:
2174:
2050:
2006:
1722:
1662:
399:
645:
Common side effects include vomiting, headache, and dizziness. Other side effects may include
3148:
3063:
2490:
2180:
331:
286:
2415:
2100:
1621:
799:
737:
Tafenoquine contains a stereocenter and consists of two enantiomers. This is a mixture of (
351:
8:
3158:
2460:
2301:
1667:
666:
470:
277:
164:
2727:
1430:
1403:
1310:
1283:
1239:
Markus MB (November 2019). "Killing of
Plasmodium vivax by Primaquine and Tafenoquine".
30:
2273:
2080:
1862:
1765:
1264:
1118:
1087:
1060:
1029:
967:
942:
890:
865:
772:
757:
131:
2819:
2368:
1811:
1747:
1435:
1315:
1268:
1256:
1193:
1123:
1065:
972:
895:
646:
239:
93:
2510:
1334:"Krintafel (tafenoquine succinate tablets) FDA Advisory Committee Briefing Document"
3093:
2918:
2806:
1869:
1848:
1425:
1415:
1305:
1295:
1284:"Putative Contribution of 8-Aminoquinolines to Preventing Recrudescence of Malaria"
1248:
1185:
1113:
1103:
1055:
1045:
962:
954:
913:
885:
877:
709:
703:
662:
638:
487:
311:
194:
1596:"US FDA approves Krintafel (tafenoquine) for the radical cure of P. vivax malaria"
3122:
2946:
2908:
2903:
2570:
2425:
2237:
1475:
1189:
811:
2485:
2480:
2475:
2982:
2928:
2893:
2330:
1989:
1840:
1671:
1300:
881:
1829:
3132:
2977:
2898:
2565:
2560:
2465:
2305:
1970:
1773:
1663:
1252:
1333:
22:
2987:
2972:
2923:
2692:
2361:
2291:
2277:
2126:
2106:
1939:
1925:
1802:
1778:
1736:
1712:
1675:
1439:
1319:
1260:
1197:
1127:
1069:
976:
958:
899:
430:
189:
2936:
2913:
2585:
2245:
2155:
2131:
2116:
2111:
2065:
2014:
1975:
1857:
1852:
1783:
1706:
1695:
1420:
1050:
795:
719:
650:
87:
1108:
642:. It may be used to prevent all types of malaria. It is taken by mouth.
2992:
2941:
2849:
2801:
2615:
2605:
2600:
2590:
2470:
2168:
2096:
2075:
2060:
1953:
1899:
1873:
1788:
714:
698:
673:
526:
322:
171:
661:
may occur. Use in pregnancy is not recommended. Tafenoquine is in the
3075:
2859:
2839:
2796:
2791:
2771:
2766:
2707:
2677:
2657:
2610:
2595:
2580:
2121:
2070:
2019:
1994:
1983:
1909:
1878:
1684:
658:
297:
73:
2844:
2834:
2829:
2824:
2781:
2717:
2712:
2687:
2667:
2652:
2647:
2550:
379:
371:
115:
1178:
Transactions of the Royal
Society of Tropical Medicine and Hygiene
866:"The evolution of tafenoquine--antimalarial for a new millennium?"
549:
2814:
2776:
2758:
2722:
2682:
2662:
2642:
2384:
2263:
1904:
1456:(Press release). Medicines for Malaria Venture. 21 September 2018
1088:"Clinical utility of tafenoquine in the prevention of relapse of
633:
1092:
malaria: a review on the mode of action and emerging trial data"
1034:
Malaria
Prophylaxis and Radical Cure: Overview and Perspectives"
2854:
2702:
2697:
2672:
2440:
2420:
1004:"Tafenoquine Succinate (Krintafel) Monograph for Professionals"
410:
2153:
823:
540:
390:
1598:(Press release). Medicines for Malaria Venture. 20 July 2018
1174:
1147:"Tafenoquine Approved for Malaria Prophylaxis and Treatment"
455:
2864:
827:
632:
among others, is a medication used to prevent and to treat
362:
1085:
572:
FC(F)(F)c3cc(Oc1c(OC)cc(NC(C)CCCN)c2nc(OC)cc(c12)C)ccc3
2353:
814:. While another is made by 60 Degrees Pharmaceutical.
3106:
1086:
Hounkpatin AB, Kreidenweiss A, Held J (March 2019).
906:
3130:
1528:"Drug Approval Package: Krintafel (tafenoquine)"
1369:"Krintafel Orphan Drug Designation and Approval"
310:
3028:GlaxoSmithKline Services Unlimited v Commission
1141:
1139:
1137:
722:, that kills the parasites in the bloodstream.
285:
940:
2369:
1648:
1134:
941:Haston JC, Hwang J, Tan KR (November 2019).
859:
857:
438:
119:
1168:
947:MMWR. Morbidity and Mortality Weekly Report
2376:
2362:
1655:
1641:
1152:Centers for Disease Control and Prevention
998:
996:
994:
992:
990:
988:
986:
469:
330:
29:
1429:
1419:
1309:
1299:
1117:
1107:
1081:
1079:
1059:
1049:
1038:Therapeutics and Clinical Risk Management
966:
936:
934:
932:
930:
928:
926:
924:
922:
889:
854:
350:
1401:
1288:Tropical Medicine and Infectious Disease
1030:"Safety and Efficacy of Tafenoquine for
870:Journal of the Royal Society of Medicine
822:Etaquine was a generic name proposed by
697:Tafenoquine is used for eliminating the
3021:Christopher v. SmithKline Beecham Corp.
983:
465:
92:
3131:
1281:
1238:
1076:
1027:
919:
914:Use During Pregnancy and Breastfeeding
863:
805:
2496:Recherche et Industrie Thérapeutiques
2357:
1636:
1576:from the original on 23 November 2019
1542:from the original on 23 November 2019
1508:from the original on 23 November 2019
1383:from the original on 23 November 2019
1349:from the original on 23 November 2019
912:
802:status in 2013 in the United States.
418:
398:
233:
110:
78:
1628:. U.S. National Library of Medicine.
193:
2411:GlaxoSmithKline Pharmaceuticals Ltd
378:
370:
301:
13:
1562:"Drug Trials Snapshots: Krintafel"
268:-quinolin-8-yl]pentane-1,4-diamine
14:
3180:
3035:United States v. Glaxo Group Ltd.
1614:
220:
142:
3116:
3089:
3088:
3042:United States v. GlaxoSmithKline
1494:"Drug Approval Package: Arakoda"
1402:Tan KR, Hwang J (January 2018).
771:
756:
510:
504:
498:
3059:Drug Industry Documents Archive
1588:
1554:
1520:
1486:
1468:
1446:
1395:
1361:
1326:
1275:
1232:
826:, and subsequently rejected by
597:Key:LBHLFPGPEGDCJG-UHFFFAOYSA-N
3014:Canada v. GlaxoSmithKline Inc.
2192:piperaquine/dihydroartemisinin
1204:
1021:
843:Arakoda (USA), Krintafel (USA)
679:
516:
492:
64:Etaquine, WR 238605, SB-252263
1:
1756:trimethoprim/sulfamethoxazole
1096:Infection and Drug Resistance
847:
684:
2154:Fixed-dose (co-formulated)
1568:Food and Drug Administration
1534:Food and Drug Administration
1500:Food and Drug Administration
1375:Food and Drug Administration
1342:Food and Drug Administration
1190:10.1016/j.trstmh.2008.04.024
798:designation and was granted
732:
692:
628:, sold under the brand name
7:
751:Enantiomers of tafenoquine
665:family of medications. The
10:
3185:
3144:Drugs developed by GSK plc
1408:Journal of Travel Medicine
1301:10.3390/tropicalmed8050278
882:10.1177/014107689909200705
789:
482:Chemical and physical data
56:Krintafel, Arakoda, others
3164:Trifluoromethyl compounds
3084:
3051:
3005:
2955:
2884:
2877:
2751:
2630:
2538:
2531:
2524:
2516:Smith, Kline & French
2451:
2435:
2398:
2391:
2314:
2290:
2262:
2236:
2200:
2144:
2089:
2049:
2036:sulfadoxine/pyrimethamine
2028:
2005:
1961:
1952:
1918:
1892:
1839:
1828:
1819:
1810:
1801:
1764:
1746:
1721:
1705:
1694:
1683:
750:
605:
580:
560:
538:
525:
486:
481:
449:
429:
409:
389:
361:
341:
321:
296:
276:
253:
248:
210:
205:
180:
170:
156:
130:
100:
86:
68:
60:
50:
42:
37:
28:
2506:S. E. Massengill Company
2406:GlaxoSmithKline Pakistan
1253:10.1016/j.pt.2019.08.009
817:
659:red blood cell breakdown
649:, trouble sleeping, and
2501:Reliant Pharmaceuticals
2383:
2187:artesunate/pyronaridine
2164:artemether/lumefantrine
1626:Drug Information Portal
810:One version is made by
2175:artesunate/amodiaquine
1282:Markus MB (May 2023).
1241:Trends in Parasitology
959:10.15585/mmwr.mm6846a4
864:Peters W (July 1999).
3064:GlaxoSmithKline Prize
2491:Human Genome Sciences
2209:artesunate/mefloquine
2181:artesunate/mefloquine
46:ta fen' oh kwin
2461:Allen & Hanburys
2416:Stiefel Laboratories
2221:quinine/tetracycline
1893:4-Methanolquinolines
1668:antiprotozoal agents
1504:. 13 February 2019.
1051:10.2147/TCRM.S269336
800:breakthrough therapy
3139:Antimalarial agents
2218:quinine/doxycycline
2215:quinine/clindamycin
2203:(not co-formulated)
1109:10.2147/IDR.S151031
840:Kodatef (Australia)
837:Kozenis (Australia)
806:Society and culture
667:mechanism of action
229:(Prescription only)
25:
2968:Silas M. Burroughs
2511:SmithKline Beecham
2476:Burroughs Wellcome
2341:Never to phase III
2201:Other combinations
2081:dihydroartemisinin
1863:hydroxychloroquine
1538:. 24 August 2018.
1421:10.1093/jtm/tay071
1028:Markus MB (2021).
21:
3104:
3103:
3001:
3000:
2873:
2872:
2747:
2746:
2447:
2446:
2351:
2350:
2286:
2285:
2258:
2257:
2254:
2253:
2232:
2231:
2228:
2227:
2140:
2139:
2045:
2044:
1948:
1947:
1797:
1796:
1723:Cryptosporidiosis
1572:. 6 August 2018.
1184:(11): 1095–1101.
953:(46): 1062–1068.
787:
786:
783:
768:
653:. In people with
647:methemoglobinemia
623:
622:
551:Interactive image
451:CompTox Dashboard
237:
224:
146:
113:
16:Antimalarial drug
3176:
3121:
3120:
3119:
3112:
3092:
3091:
2919:Patrick Vallance
2882:
2881:
2611:Wellbutrin/Zyban
2536:
2535:
2529:
2528:
2396:
2395:
2378:
2371:
2364:
2355:
2354:
2151:
2150:
1959:
1958:
1837:
1836:
1826:
1825:
1817:
1816:
1808:
1807:
1719:
1718:
1703:
1702:
1692:
1691:
1674:antiparasitics (
1657:
1650:
1643:
1634:
1633:
1629:
1608:
1607:
1605:
1603:
1592:
1586:
1585:
1583:
1581:
1558:
1552:
1551:
1549:
1547:
1524:
1518:
1517:
1515:
1513:
1490:
1484:
1483:
1480:NPS MedicineWise
1472:
1466:
1465:
1463:
1461:
1450:
1444:
1443:
1433:
1423:
1399:
1393:
1392:
1390:
1388:
1365:
1359:
1358:
1356:
1354:
1345:. 12 July 2018.
1338:
1330:
1324:
1323:
1313:
1303:
1279:
1273:
1272:
1236:
1230:
1229:
1227:
1225:
1216:
1208:
1202:
1201:
1172:
1166:
1165:
1163:
1161:
1143:
1132:
1131:
1121:
1111:
1090:Plasmodium vivax
1083:
1074:
1073:
1063:
1053:
1032:Plasmodium vivax
1025:
1019:
1018:
1016:
1014:
1000:
981:
980:
970:
938:
917:
916:
910:
904:
903:
893:
861:
777:
775:
762:
760:
748:
747:
710:Plasmodium ovale
704:Plasmodium vivax
663:8-aminoquinoline
639:Plasmodium vivax
619:
618:
611:
553:
533:
518:
512:
506:
500:
494:
474:
473:
459:
457:
442:
422:
402:
382:
374:
354:
334:
314:
304:
303:
289:
235:
232:
222:
219:
197:
144:
141:
123:
112:
109:
96:
82:
33:
26:
24:
20:
3184:
3183:
3179:
3178:
3177:
3175:
3174:
3173:
3129:
3128:
3127:
3117:
3115:
3107:
3105:
3100:
3080:
3047:
2997:
2951:
2947:Laurie Glimcher
2914:Manvinder Banga
2909:Roy M. Anderson
2904:Simon Dingemans
2886:
2869:
2743:
2626:
2520:
2453:
2443:
2431:
2426:ViiV Healthcare
2387:
2382:
2352:
2347:
2346:
2331:Clinical trials
2310:
2293:
2282:
2265:
2250:
2224:
2202:
2196:
2146:
2136:
2085:
2052:
2041:
2024:
2001:
1963:DHFR inhibitors
1944:
1914:
1888:
1841:Aminoquinolines
1831:
1821:
1793:
1760:
1742:
1710:
1697:
1686:
1679:
1661:
1620:
1617:
1612:
1611:
1601:
1599:
1594:
1593:
1589:
1579:
1577:
1560:
1559:
1555:
1545:
1543:
1526:
1525:
1521:
1511:
1509:
1492:
1491:
1487:
1474:
1473:
1469:
1459:
1457:
1452:
1451:
1447:
1400:
1396:
1386:
1384:
1367:
1366:
1362:
1352:
1350:
1336:
1332:
1331:
1327:
1280:
1276:
1247:(11): 857–859.
1237:
1233:
1223:
1221:
1214:
1210:
1209:
1205:
1173:
1169:
1159:
1157:
1156:. 25 April 2019
1145:
1144:
1135:
1084:
1077:
1026:
1022:
1012:
1010:
1002:
1001:
984:
939:
920:
911:
907:
862:
855:
850:
820:
812:GlaxoSmithKline
808:
792:
776:
761:
735:
695:
687:
682:
655:G6PD deficiency
614:
612:
609:(what is this?)
606:
601:
598:
593:
588:
587:
576:
573:
568:
567:
556:
531:
521:
515:
509:
503:
497:
477:
453:
445:
425:
405:
385:
357:
337:
317:
300:
292:
272:
269:
261:
260:
244:
201:
159:
152:
133:
126:
17:
12:
11:
5:
3182:
3172:
3171:
3166:
3161:
3156:
3151:
3146:
3141:
3126:
3125:
3102:
3101:
3099:
3098:
3085:
3082:
3081:
3079:
3078:
3073:
3066:
3061:
3055:
3053:
3049:
3048:
3046:
3045:
3038:
3031:
3024:
3017:
3009:
3007:
3003:
3002:
2999:
2998:
2996:
2995:
2990:
2985:
2983:Henry Wellcome
2980:
2975:
2970:
2965:
2963:Thomas Beecham
2959:
2957:
2953:
2952:
2950:
2949:
2944:
2939:
2934:
2931:
2929:Lynn Elsenhans
2926:
2921:
2916:
2911:
2906:
2901:
2896:
2894:Philip Hampton
2890:
2888:
2879:
2875:
2874:
2871:
2870:
2868:
2867:
2862:
2857:
2852:
2847:
2842:
2837:
2832:
2827:
2822:
2820:Goody's Powder
2817:
2812:
2809:
2804:
2799:
2794:
2789:
2784:
2779:
2774:
2769:
2764:
2761:
2755:
2753:
2749:
2748:
2745:
2744:
2742:
2741:
2730:
2725:
2720:
2715:
2710:
2705:
2700:
2695:
2690:
2685:
2680:
2675:
2670:
2665:
2660:
2655:
2650:
2645:
2640:
2634:
2632:
2628:
2627:
2625:
2624:
2613:
2608:
2603:
2598:
2593:
2588:
2583:
2578:
2573:
2568:
2563:
2558:
2553:
2548:
2542:
2540:
2533:
2526:
2522:
2521:
2519:
2518:
2513:
2508:
2503:
2498:
2493:
2488:
2486:Glaxo Wellcome
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1622:"Tafenoquine"
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43:Pronunciation
41:
38:Clinical data
36:
32:
27:
19:
3149:Orphan drugs
3094:
3070:Side Effects
3068:
3040:
3033:
3026:
3019:
3012:
2988:Andrew Witty
2973:Mahlon Kline
2924:Vivienne Cox
2737:
2693:H5N1 vaccine
2620:
2454:acquisitions
2392:Subsidiaries
2278:tetracycline
2171:/piperaquine
2127:pyronaridine
2107:tetracycline
2007:Sulfonamides
1982:
1940:halofantrine
1931:+ artemether
1926:lumefantrine
1883:
1803:Aconoidasida
1779:sulfadiazine
1748:Isosporiasis
1737:nitazoxanide
1730:
1625:
1600:. Retrieved
1590:
1578:. Retrieved
1565:
1556:
1544:. Retrieved
1531:
1522:
1510:. Retrieved
1497:
1488:
1479:
1470:
1458:. Retrieved
1448:
1411:
1407:
1397:
1385:. Retrieved
1372:
1363:
1351:. Retrieved
1340:
1328:
1291:
1287:
1277:
1244:
1240:
1234:
1222:. Retrieved
1218:
1206:
1181:
1177:
1170:
1158:. Retrieved
1150:
1099:
1095:
1089:
1041:
1037:
1031:
1023:
1011:. Retrieved
1007:
950:
946:
908:
873:
869:
833:Trade names
832:
821:
809:
793:
779:
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742:
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736:
726:
724:
708:
702:
696:
688:
671:
644:
637:
629:
625:
624:
613:
607:
431:NIAID ChemDB
420:ChEMBL298470
400:CHEBI:135752
265:
212:Legal status
206:Legal status
176:Antimalarial
102:License data
18:
2937:Judy Lewent
2327:from market
2246:clindamycin
2132:piperaquine
2117:clindamycin
2112:doxycycline
2101:+ proguanil
2066:artemisinin
2015:sulfadoxine
1976:cycloguanil
1954:Antifolates
1884:tafenoquine
1858:chloroquine
1853:amodiaquine
1820:Individual
1784:clindamycin
1732:thiazolides
1707:Conoidasida
1580:22 November
1546:22 November
1512:22 November
1387:22 November
1353:22 November
1224:22 November
1160:22 November
1102:: 553–570.
1044:: 989–999.
1013:22 November
796:orphan drug
720:chloroquine
680:Medical use
651:anaphylaxis
626:Tafenoquine
534: g·mol
287:106635-80-7
249:Identifiers
121:Tafenoquine
88:MedlinePlus
61:Other names
52:Trade names
23:Tafenoquine
3159:Quinolines
3133:Categories
3006:Litigation
2993:Chris Gent
2942:Urs Rohner
2850:Parodontax
2658:Engerix-B
2471:Block Drug
2238:Babesiosis
2169:arterolane
2097:atovaquone
2076:artesunate
2061:artemether
1984:biguanides
1900:mefloquine
1874:primaquine
1832:inhibitors
1789:atovaquone
1602:15 October
1460:15 October
1294:(5): 278.
848:References
745:) - Form:
715:Primaquine
699:hypnozoite
685:Prevention
674:primaquine
539:3D model (
527:Molar mass
352:262P8GS9L9
323:ChemSpider
278:CAS Number
258:IUPAC name
172:Drug class
3076:Study 329
2887:Directors
2885:Board of
2860:Sensodyne
2840:Nicorette
2797:Emergen-C
2792:ChapStick
2772:BC Powder
2767:Aquafresh
2708:Pandemrix
2678:Hepatyrix
2576:Flixonase
2556:Augmentin
2337:Phase III
2325:Withdrawn
2122:mepacrine
2071:artemotil
2020:sulfalene
1995:proguanil
1910:quinidine
1879:pamaquine
1476:"Kodatef"
1269:202582476
1008:Drugs.com
733:Chemistry
701:stage of
693:Treatment
630:Krintafel
158:Routes of
132:Pregnancy
80:Monograph
74:Drugs.com
3123:Medicine
3095:Category
2845:NiQuitin
2835:Nicoderm
2830:Lucozade
2825:Horlicks
2807:Excedrin
2782:Caltrate
2728:Shingrix
2718:Rabavert
2713:Pediarix
2688:Infanrix
2668:FluLaval
2653:Cervarix
2648:Boostrix
2631:Vaccines
2606:Ventolin
2596:Serlipet
2586:Lamictal
2581:Hycamtin
2566:Beconase
2525:Products
2292:Stramen-
2053:lactones
1830:Hemozoin
1574:Archived
1540:Archived
1506:Archived
1440:30137454
1431:10956546
1381:Archived
1347:Archived
1320:37235326
1311:10223033
1261:31522991
1198:18541280
1128:30881061
1070:34526770
977:31751320
900:10615272
727:P. vivax
616:(verify)
182:ATC code
165:By mouth
134:category
116:DailyMed
2815:Geritol
2811:Flonase
2787:Centrum
2777:Biotene
2759:Actifed
2733:Twinrix
2723:Rotarix
2683:Hiberix
2663:Fluarix
2643:Bexsero
2601:Tagamet
2561:Avandia
2532:Current
2399:Current
2147:nations
1905:quinine
1812:Malaria
1696:Apicom-
1119:6411314
1061:8435617
968:6871897
891:1297286
790:History
782:)-Form
767:)-Form
634:malaria
532:463.501
488:Formula
298:PubChem
198:)
192: (
190:P01BA07
147: C
118::
94:a618050
3109:Portal
2878:People
2855:Ribena
2752:Former
2703:Menveo
2698:Kinrix
2673:Havrix
2638:Arexvy
2616:Zantac
2571:Boniva
2546:Advair
2539:Pharma
2441:Haleon
2436:Former
2421:Tesaro
2320:WHO-EM
2264:Cilio-
2183:(ASMQ)
2177:(ASAQ)
2145:Combi-
1822:agents
1685:Alveo-
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565:SMILES
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411:ChEMBL
380:D10670
372:D10490
332:103196
312:115358
240:℞-only
238:
225:
114:
3052:Other
2956:Other
2763:Advil
2481:Glaxo
2428:(85%)
2294:opile
2266:phora
2090:Other
1919:Other
1698:plexa
1570:(FDA)
1566:U.S.
1536:(FDA)
1532:U.S.
1502:(FDA)
1498:U.S.
1414:(1).
1377:(FDA)
1373:U.S.
1337:(PDF)
1265:S2CID
1215:(PDF)
1154:(CDC)
824:WRAIR
818:Names
585:InChI
541:JSmol
391:ChEBI
2865:Tums
2738:more
2621:more
2551:Alli
2156:ACTs
2038:(SP)
1870:(8-)
1849:(4-)
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1257:PMID
1226:2019
1194:PMID
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1124:PMID
1066:PMID
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896:PMID
828:CDER
707:and
363:KEGG
343:UNII
70:AHFS
2802:Eno
2385:GSK
1676:P01
1426:PMC
1416:doi
1306:PMC
1296:doi
1249:doi
1219:WHO
1186:doi
1182:102
1114:PMC
1104:doi
1056:PMC
1046:doi
963:PMC
955:doi
886:PMC
878:doi
456:EPA
302:CID
195:WHO
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