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Single-cell protein

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123:(FAO) emphasized on hunger and malnutrition problems of the world in 1960 and introduced the concept of protein gap, showing that 25% of the world population had a deficiency of protein intake in their diet. It was also feared that agricultural production would fail to meet the increasing demands of food by humanity. By the mid 60’s, almost quarter of a million tons of food yeast were being produced in different parts of the world and Soviet Union alone produced some 900,000 tons by 1970 of food and fodder yeast. 2659: 613:
Cultivation of microorganisms generally has a much lower water footprint than agricultural food production. Whereas the global average blue-green water footprint (irrigation, surface, ground and rain water) of crops reaches about 1800 liters per kg crop due to evaporation, transpiration, drainage and
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The problem with extracting single-cell proteins from the wastes is the dilution and cost. They are found in very low concentrations, usually less than 5%. Engineers have developed ways to increase the concentrations including centrifugation, flotation, precipitation, coagulation, and filtration, or
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Unlike agricultural products which are processed towards a desired quality, it is easier with microorganisms to direct production towards a desired quality. Instead of extracting amino acids from soy beans and throwing away half of the plant body in the process, microorganisms can be genetically
176:(1974). The Soviet Ministry of Microbiological Industry had eight plants of this kind by 1989. However, due to concerns of toxicity of alkanes in SCP and pressured by the environmentalist movements, the government decided to close them down, or convert to some other microbiological processes. 245:
The single-cell protein must be dehydrated to approximately 10% moisture content and/or acidified to aid in storage and prevent spoilage. The methods to increase the concentrations to adequate levels and the de-watering process require equipment that is expensive and not always suitable for
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reaching 9 billion by 2050, there is strong evidence that agriculture will not be able to meet demand and that there is serious risk of food shortage. Autotrophic SCP represents options of fail-safe mass food-production which can produce food reliably even under harsh climate conditions.
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Pobiega, Katarzyna; Sękul, Joanna; Pakulska, Anna; Latoszewska, Małgorzata; Michońska, Aleksandra; Korzeniowska, Zuzanna; Macherzyńska, Zuzanna; Pląder, Michał; Duda, Wiktoria; Szafraniuk, Jakub; Kufel, Aniela; Dominiak, Łukasz; Lis, Zuzanna; Kłusek, Emilia; Kozicka, Ewa (January 2024).
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modified to overproduce or even secrete a particular amino acid. However, in order to keep a good consumer acceptance, it is usually easier to obtain similar results by screening for microorganisms which already have the desired trait or train them via selective adaptation.
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Cultivation of microorganisms does not require fertile soil and therefore does not compete with agriculture. Thanks to the low water requirements, SCP cultivation can even be done in dry climates with infertile soil and may provide a means of fail-safe food supply in arid
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growth. Thanks to the high diversity of microbial metabolism, autotrophic SCP provides several different modes of growth, versatile options of nutrients recycling, and a substantially increased efficiency compared to crops. A 2021 publication showed that
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Similar to plant cells, the cell wall of some microorganisms such as algae and yeast contains indigestible components, such as cellulose. The cells of some kind of SCP should be broken up in order to liberate the cell interior and allow complete
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Whereas large parts of crops, such as stems, leaves and roots, are not edible, single-cell microorganisms can be used entirely. Whereas parts of the edible fraction of crops are indigestible, many microorganisms are digestible at a much higher
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Microorganisms can utilize a broad spectrum of raw materials as carbon sources including alkanes, methanol, methane, ethanol and sugars. What was considered "waste product" often can be reclaimed as nutrients and support growth of edible
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Microorganisms have a much higher growth rate (algae: 2–6 hours, yeast: 1–3 hours, bacteria: 0.5–2 hours). This also allows selection for strains with high yield and good nutritional composition more quickly and easily compared to
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Microorganisms usually have a much higher protein content of 30–70% in the dry mass than vegetables or grains. The amino acid profiles of many SCP microorganisms often have excellent nutritional quality, comparable to hen's
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ferment waste materials (including wood, straw, cannery, and food-processing wastes, residues from alcohol production, hydrocarbons, or human and animal excreta). With 'electric food' processes the inputs are electricity,
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from the air and are thus independent of chemical N-fertilizer, whose production, utilization and degradation causes tremendous harm to the environment, deteriorates public health, and fosters climate change.
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developed what they called "proteins-from-oil process": a technology for producing single-cell protein by yeast fed by waxy n-paraffins, a byproduct of oil refineries. Initial research work was done by
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British Petroleum and global oil, 1950–1975: the challenge of nationalism. Volume 3 of British Petroleum and Global Oil 1950–1975: The Challenge of Nationalism, J. H. Bamberg British Petroleum series
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Microbial biomass production is independent of seasonal and climatic variations, and can easily be shielded from extreme weather events that are expected to cause crop failures with the ongoing
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Depending on the kind of SCP and the cultivation conditions, care must be taken to prevent and control contamination by other microorganisms because contaminants may produce toxins such as
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and his colleagues found out the high value of surplus brewer’s yeast as a feeding supplement for animals. During World War I and World War II, yeast-SCP was employed on a large scale in
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Bartholomai, Bradley M.; Ruwe, Katherine M.; Thurston, Jonathan; Jha, Prachi; Scaife, Kevin; Simon, Ryan; Abdelmoteleb, Mohamed; Goodman, Richard E.; Farhi, Moran (2022-10-01).
2491: 70:; production of SCP does not necessarily exhibit any of these serious drawbacks. As of today, SCP is commonly grown on agricultural waste products, and as such inherits the 515:
Some microorganisms can build vitamins and nutrients which eukaryotic organisms such as plants cannot produce or not produce in significant amounts, including vitamin B12.
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may be used as an ingredient or a substitute for protein-rich foods, and is suitable for human consumption or as animal feeds. Industrial agriculture is marked by a high
788: 673:, which is excreted in urine. Nucleic acid removal is not necessary from animal feeds but is from human foods. A temperature hold at 64 °C inactivates fungal 107:
to counteract food shortages during the war. Inventions for SCP production often represented milestones for biotechnology in general: for example, in 1919, Sak in
353: 120: 2330: 1929:"Unlocking the genomic potential of aerobes and phototrophs for the production of nutritious and palatable microbial food without arable land or fossil fuels" 677:. However, this problem can be remediated. One common method consists in a heat treatment which kills the cells, inactivates proteases and allows endogenous 99:
In 1781, processes for preparing highly concentrated forms of yeast were established. Research on Single Cell Protein Technology started a century ago when
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at BP's Lavera Oil Refinery in France; a small pilot plant there started operations in March 1963, and the same construction of the second pilot plant, at
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Koukoumaki, Danai Ioanna; Tsouko, Erminta; Papanikolaou, Seraphim; Ioannou, Zacharias; Diamantopoulou, Panagiota; Sarris, Dimitris (2024-06-01).
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which grows at a pH as low as 1, outside the tolerance of most microorganisms. This allows it to grow on acid-hydrolysed paper waste at low-cost.
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Although SCP shows very attractive features as a nutrient for humans, however there are some problems that deter its adoption on global basis:
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Photosynthetic microorganisms can reach a higher solar-energy-conversion efficiency than plants, because in photobioreactors supply of water, CO
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in 1976, and paraffin-fed yeast facilities being built in a number of countries. The primary use of the product was as poultry and cattle feed.
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and water footprint of industrial agriculture. However, SCP may also be produced entirely independent of agricultural waste products through
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Large-scale production of microbial biomass has many advantages over the traditional methods for producing proteins for food or feed.
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Vrati S (1983). "Single cell protein production by photosynthetic bacteria grown on the clarified effluents of biogas plant".
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Boyle NR, Morgan JA (March 2011). "Computation of metabolic fluxes and efficiencies for biological carbon dioxide fixation".
2051: 1245: 1218: 2663: 2619: 1865:"Single-Cell Protein Production by the Acid-Tolerant Fungus Scytalidium acidophilum from Acid Hydrolysates of Waste Paper" 1435:"Making the case for edible microorganisms as an integral part of a more sustainable and resilient food production system" 1407: 1331: 2540: 2440: 538:
with efficiencies ranging from 2-3 times to 10 times more efficiently than plants, when also considering the effects of
1639:"Killing two birds with one stone: chemical and biological upcycling of polyethylene terephthalate plastics into food" 2246: 1272: 832:"Photovoltaic-driven microbial protein production can use land and sunlight more efficiently than conventional crops" 2689: 2322: 1388:(Microbiological industry's first plant), in: Станислав Марков (Stanislav Markov) «Кстово – молодой город России» ( 793: 1033:"Agriculture-independent, sustainable, fail-safe and efficient food production by autotrophic single-cell protein" 198:
Another type of single cell protein-based meat analogue (which does not use fungi however but rather bacteria) is
1694:"Fungal Proteins: Sources, Production and Purification Methods, Industrial Applications, and Future Perspectives" 1733:
Thiviya, Punniamoorthy; Gamage, Ashoka; Kapilan, Ranganathan; Merah, Othmane; Madhujith, Terrence (July 2022).
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small-scale operations. It is economically prudent to feed the product locally and soon after it is produced.
2264:"Biotechnological Production of Sustainable Microbial Proteins from Agro-Industrial Residues and By-Products" 2201: 2184: 2679: 1588:"Methane Single Cell Protein: Potential to Secure a Global Protein Supply Against Catastrophic Food Shocks" 932:"Global environmental impacts of agricultural expansion: the need for sustainable and efficient practices" 1313:
National Research Council (U.S.). Board on Science and Technology for International Development (1983).
2470: 1292: 527: 406: 2067: 1994: 1822: 1775: 2684: 1776:"Safety evaluation of Neurospora crassa mycoprotein for use as a novel meat alternative and enhancer" 470: 59: 1995:"Recent advances in the production of single cell protein from renewable resources and applications" 1823:"A review on mycoprotein: History, nutritional composition, production methods, and health benefits" 485: 419: 266: 259: 1102:
Godfray HC, Beddington JR, Crute IR, Haddad L, Lawrence D, Muir JF, et al. (February 2010).
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Ahmad, Muhammad Ijaz; Farooq, Shahzad; Alhamoud, Yasmin; Li, Chunbao; Zhang, Hui (2022-03-01).
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The "food from oil" idea became quite popular by the 1970s, with Champagnat being awarded the
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or cyanotoxins. An interesting approach to address this problem was proposed with the fungus
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and trace minerals and chemicals such as fertiliser. It is also possible to derive SCP from
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that can be made by gasification of residual intractable biowastes such as lignocellulose.
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Alloul, Abbas; Spanoghe, Janne; Machado, Daniel; Vlaeminck, Siegfried E. (January 2022).
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Schaerer LG, Wu R, Putman LI, Pearce JM, Lu T, Shonnard DR, et al. (February 2023).
1378: 546: 531: 426: 313: 273: 2137: 2010: 1880: 1164: 1151:
Wheeler T, von Braun J (August 2013). "Climate change impacts on global food security".
1119: 1080: 947: 847: 2290: 2263: 2214: 2156: 2121: 1961: 1928: 1668: 1614: 1587: 1553: 1510: 1483: 1464: 1316:
Workshop on Single-Cell Protein: summary report, Jakarta, Indonesia, February 1–5, 1983
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García Martínez JB, Pearce JM, Throup J, Cates J, Lackner M, Denkenberger DC (2022).
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Fast growing microorganisms such as bacteria and yeast have a high concentration of
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Some bacteria, such as several homoacetogenic clostridia, are capable of performing
2590: 2285: 2275: 2218: 2196: 2151: 2141: 2094: 2014: 1956: 1940: 1892: 1884: 1834: 1787: 1746: 1705: 1650: 1609: 1599: 1545: 1505: 1495: 1446: 1188: 1168: 1123: 1084: 1040: 1002: 961: 951: 905: 861: 851: 803: 766: 87: 1888: 1655: 1638: 1484:"Single Cell Protein-State-of-the-Art, Industrial Landscape and Patents 2001-2016" 910: 893: 2595: 2578: 2351: 2236: 1411: 1385: 1314: 1262: 1235: 1045: 772: 539: 55: 2579:"Recent advances in single cell protein use as a feed ingredient in aquaculture" 2376:"Kiverdi Uses NASA Technology To Make Protein, Fish Food, and Palm Oil from CO2" 2098: 2019: 1060:
Challinor AJ, Watson J, Lobell DB, Howden SM, Smith DR, Chhetri N (2014-01-01).
610:. Light-independent microorganisms such as yeasts can continue to grow at night. 100: 2126:
Proceedings of the National Academy of Sciences of the United States of America
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Proceedings of the National Academy of Sciences of the United States of America
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Proceedings of the National Academy of Sciences of the United States of America
798: 607: 301: 67: 63: 1791: 1604: 168:, i.e., "protein-vitamin concentrate") plants next to their oil refineries in 2673: 2432: 2210: 2028: 1952: 1846: 1799: 1760: 1719: 1500: 1460: 1211:
Applied mycology and biotechnology. Volume 2: agriculture and food production
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Bajić B, Vučurović D, Vasić Đ, Jevtić-Mučibabić R, Dodić S (December 2022).
2146: 1944: 1172: 1128: 1103: 956: 856: 2604: 2299: 2165: 2106: 1970: 1906: 1807: 1664: 1623: 1519: 1180: 1137: 975: 875: 654: 638: 294: 161: 2280: 603:, in a manner of speaking, those bacteria can be "powered by electricity". 2638:"BioCity invests in carbon recycling start-up, Deep Branch Biotechnology" 2560:"A new nutrient for aquaculture, from microbes that consume carbon waste" 2042:
Litchfield JH (16 March 1989). "Single-cell proteins". In Marx JL (ed.).
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runoff, closed bioreactors producing SCP exhibits none of these causes.
1735:"Single Cell Protein Production Using Different Fruit Waste: A Review" 830:
Leger D, Matassa S, Noor E, Shepon A, Milo R, Bar-Even A (June 2021).
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SCP has been argued to be a source of alternative or resilient food.
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Like plants, autotrophic microorganisms are capable of growing on CO
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and Hayduck in Germany invented a method named, “Zulaufverfahren”, (
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Jones SW, Karpol A, Friedman S, Maru BT, Tracy BP (February 2020).
2261: 1992: 1062:"A meta-analysis of crop yield under climate change and adaptation" 674: 387: 214: 51: 746: 199: 173: 108: 104: 35: 2396: 2068:"What is Single Cell Protein (SCP)? Definition & Properties" 1585: 2658: 1690: 778: 723:: a single cell protein made by Solar Foods Ltd. Finland-based. 720: 646: 550: 321: 169: 43: 2414: 1926: 2178: 1573:"Plan to sell 50m meals made from electricity, water and air" 678: 434: 179: 47: 39: 2492:"Introducing Superbrewed Food's postbiotic cultured protein" 2462: 1482:
Ritala A, Häkkinen ST, Toivari M, Wiebe MG (March 1, 2017).
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and a balanced light distribution can be tightly controlled.
2122:"Design and analysis of synthetic carbon fixation pathways" 1059: 662: 1773: 1481: 1104:"Food security: the challenge of feeding 9 billion people" 755:
Superbrewed Food (formerly White Dog Labs). Delaware-based
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10.1641/0006-3568(2003)053[0341:TNC]2.0.CO;2
591:. This feature allows autotrophic bacteria to grow on CO 2620:"Deep Branch Bio's Peter Rowe Wants to Save the Planet" 2576: 988: 894:"Water footprint benchmarks for crop produ160X14002660" 692:
Some kind of SCP exhibits unpleasant color and flavors.
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Food and Agriculture Organization of the United Nations
1636: 829: 641:, notably RNA. Levels must be limited in the diets of 2119: 1820: 1281: 583:-sensitive, some bacteria are capable of performing O 164:
were particularly enthusiastic, opening large "BVK" (
989:Vermeulen SJ, Campbell BM, Ingram JS (2012-01-01). 564:
Some bacteria are diazotrophic, i.e. they can fix N
58:, high land use, biodiversity destruction, general 2640:. BioCity Group Ltd. 24 April 2019. Archived from 452:, Limnospira fusiformis, L. maxima and L. indica). 38:or protein extract from pure or mixed cultures of 2391: 2389: 2183:, Howarth RW, Cowling EB, Cosby BJ (2003-04-01). 2120:Bar-Even A, Noor E, Lewis NE, Milo R (May 2010). 2671: 2369: 2367: 2365: 2358:. National Aeronautics and Space Administration. 2327:ALLFED - Alliance to Feed the Earth in Disasters 1358:European Bank for Reconstruction and Development 1240:. Cambridge University Press. pp. 426–428. 1150: 891: 706:Some yeast and fungal proteins are deficient in 1208: 887: 885: 2541:"Would you eat blue algae to save the planet?" 2386: 2352:"Carbon Capture Process Makes Sustainable Oil" 2234: 2230: 2228: 2046:. Cambridge University Press. pp. 71–81. 1026: 1024: 1022: 1020: 1018: 2362: 1862: 1592:Frontiers in Bioengineering and Biotechnology 1289:"UNESCO Science Prize: List of prize winners" 1204: 1202: 1200: 1198: 925: 923: 921: 882: 825: 823: 595:without light at a fast growth rate. Since H 579:. Whereas hydrogenases are normally highly O 2225: 2084: 1015: 2041: 1400: 1398: 1379:Первенец микробиологической промышленности 1195: 995:Annual Review of Environment and Resources 918: 645:animals to <50 g per day. Ingestion of 526:. Some of them, such as bacteria with the 2594: 2317: 2315: 2313: 2311: 2309: 2289: 2279: 2200: 2155: 2145: 2018: 1960: 1896: 1750: 1709: 1654: 1613: 1603: 1509: 1499: 1450: 1127: 1044: 1006: 965: 955: 909: 865: 855: 820: 1858: 1856: 1368:from the original on September 27, 2022. 575:for energy supply, using enzymes called 2524:. University of Antwerp. Archived from 2238:Use of Yeast Biomass in Food Production 1827:Trends in Food Science & Technology 1531: 1529: 1395: 1233: 1030: 892:Mekonnen MM, Hoekstra AY (2014-11-01). 2672: 2557: 2306: 1869:Applied and Environmental Microbiology 1570: 1538:Applied Microbiology and Biotechnology 1432: 1414:(Johnson's Russia List, Dec. 19, 2002) 1329: 1260: 1213:. Elsevier Science. pp. 123–149. 929: 2617: 2538: 2035: 1988: 1986: 1984: 1982: 1980: 1922: 1920: 1918: 1916: 1853: 1686: 1684: 1682: 1535: 1350:"RusVinyl - Summary of Social Issues" 1319:. National Academy Press. p. 40. 1008:10.1146/annurev-environ-020411-130608 242:the use of semi-permeable membranes. 208: 2519: 2460: 2373: 2323:"High-tech resilient food solutions" 1526: 752:Circe Biotechnologie - Austria-based 230:. Similarly SCP can be derived from 195:, sold in Europe and North America. 2235:Halasz A, Lasztity R (1990-12-07). 1863:Ivarson KC, Morita H (March 1982). 182:is a range of vegetarian and vegan 142:The term SCP was coined in 1966 by 13: 2522:"Purple bacteria as a type of SCP" 2179:Galloway JN, Aber JD, Erisman JW, 1977: 1913: 1679: 213:Single-cell proteins develop when 14: 2706: 2651: 1267:. World Scientific. p. 205. 991:"Climate Change and Food Systems" 681:to hydrolyse RNA with release of 549:. This means they can metabolize 249: 16:Edible unicellular microorganisms 2657: 2583:Current Opinion in Biotechnology 2356:NASA Technology Transfer program 1209:Ugalde UO, Castrillo JI (2002). 794:Fermentative hydrogen production 669:. Uric acid can be converted to 2630: 2611: 2570: 2551: 2532: 2513: 2484: 2473:from the original on 2023-10-31 2454: 2443:from the original on 2023-03-25 2425: 2407: 2344: 2333:from the original on 2023-09-23 2255: 2172: 2113: 2078: 2060: 1814: 1767: 1726: 1630: 1579: 1564: 1475: 1426: 1417: 1405:KIRISHI: A GREEN SUCCESS STORY? 1372: 1342: 1323: 1306: 1254: 1227: 775:: a type of single-cell protein 1291:. UNESCO. 2001. Archived from 1144: 1095: 1053: 982: 66:by emission of a third of all 1: 2558:Wright J (12 February 2018). 2044:A Revolution in Biotechnology 1889:10.1128/aem.43.3.643-647.1982 1656:10.1016/j.tibtech.2022.06.012 1330:Shabad T (10 November 1973). 1264:Microbial Process Development 911:10.1016/j.ecolind.2014.06.013 814: 653:breakdown leads to increased 494: 166:belkovo-vitaminny kontsentrat 126:In the 1960s, researchers at 2596:10.1016/j.copbio.2019.12.026 2498:. 2022-06-21. Archived from 1780:Food and Chemical Toxicology 1046:10.7287/peerj.preprints.1279 414:Methylophilus methylotrophus 139:in Britain, was authorized. 30:refer to edible unicellular 7: 2099:10.1016/j.ymben.2011.01.005 2020:10.1016/j.crcon.2023.07.004 1999:Carbon Resources Conversion 1390:Kstovo, Russia's Young City 714: 685:from cell to culture broth. 599:can be made efficiently by 587:-dependent respiration of H 571:Many bacteria can utilize H 254:Microbes employed include: 119:). In post war period, the 10: 2711: 1839:10.1016/j.tifs.2022.01.027 1752:10.3390/separations9070178 1452:10.1007/s12571-019-00912-3 408:Rhodopseudomonas palustris 94: 2539:Frost R (July 30, 2020). 1792:10.1016/j.fct.2022.113342 1605:10.3389/fbioe.2022.906704 1571:Boffey D (29 June 2019). 1488:Frontiers in Microbiology 789:Deep Branch Biotechnology 472:Chlamydomonas reinhardtii 60:environmental degradation 2374:Lamb C (2 August 2019). 1501:10.3389/fmicb.2017.02009 1423:EOS, april 2019, page 52 1031:Bogdahn I (2015-09-17). 553:, a gas mixture of CO, H 486:Aphanizomenon flos-aquae 267:Saccharomyces cerevisiae 137:Grangemouth Oil Refinery 2690:Biochemical engineering 2618:Terry M (13 May 2019). 2564:Global Seafood Alliance 2415:"Kiverdi's Air Protein" 2147:10.1073/pnas.0907176107 1945:10.1111/1751-7915.13747 1933:Microbial Biotechnology 1643:Trends in Biotechnology 1433:Linder T (April 2019). 1173:10.1126/science.1239402 1129:10.1126/science.1185383 957:10.1073/pnas.96.11.5995 857:10.1073/pnas.2015025118 809:Microbial food cultures 701:Scytalidium acidophilum 649:compounds arising from 420:Metylococcus capsulatus 401:Rhodobacter sphaeroides 381:Scytalidium acidophilum 288:Kluyveromyces marxianus 2463:"Single Cell Proteins" 2185:"The Nitrogen Cascade" 758:Deep Branch - UK-based 743:Unibio - Denmark-based 740:Avecom - Belgium-based 528:Wood–Ljungdahl pathway 394:Rhodobacter capsulatus 2281:10.3390/foods12010107 2087:Metabolic Engineering 1361:. February 14, 2008. 1069:Nature Climate Change 930:Tilman D (May 1999). 898:Ecological Indicators 479:Porphyridium cruentum 450:Arthrospira platensis 354:Neurospora intermedia 295:Komagataella pastoris 281:Cyberlindnera jadinii 2666:at Wikimedia Commons 2528:on 12 December 2019. 1295:on February 10, 2009 1089:10.1038/nclimate2153 308:Torulopsis corallina 155:UNESCO Science Prize 72:ecological footprint 20:Single-cell proteins 2680:Single-cell protein 2664:Single-cell protein 2138:2010PNAS..107.8889B 2011:2024CarRC...700195K 1881:1982ApEnM..43..643I 1711:10.3390/app14146259 1234:Bamberg JH (2000). 1165:2013Sci...341..508W 1120:2010Sci...327..812G 1081:2014NatCC...4..287C 948:1999PNAS...96.5995T 848:2021PNAS..11815025L 842:(26): e2015025118. 737:. California-based. 547:syngas fermentation 427:Cupriavidus necator 314:Geotrichum candidum 274:Yarrowia lipolytica 62:and contributes to 2496:Fi Global Insights 2421:. Air Protein Inc. 2403:. Air Protein Inc. 1550:10.1007/BF00256454 1410:2009-08-07 at the 1384:2019-03-27 at the 1336:The New York Times 1261:Doelle HW (1994). 749:- California-based 661:, which can cause 601:water electrolysis 361:Sclerotium rolfsii 340:Fusarium venenatum 333:Aspergillus oryzae 209:Production process 189:Fusarium venenatum 28:microbial proteins 2662:Media related to 2644:on 28 March 2020. 2132:(19): 8889–8894. 2053:978-0-521-32749-7 1247:978-0-521-78515-0 1220:978-0-444-51030-3 1159:(6145): 508–513. 1114:(5967): 812–818. 942:(11): 5995–6000. 804:Alternative foods 465:Dunaliella salina 347:Neurospora crassa 144:Carroll L. Wilson 133:Alfred Champagnat 128:British Petroleum 2702: 2685:Meat substitutes 2661: 2646: 2645: 2634: 2628: 2627: 2615: 2609: 2608: 2598: 2574: 2568: 2567: 2555: 2549: 2548: 2536: 2530: 2529: 2517: 2511: 2510: 2508: 2507: 2488: 2482: 2481: 2479: 2478: 2458: 2452: 2451: 2449: 2448: 2429: 2423: 2422: 2411: 2405: 2404: 2393: 2384: 2383: 2371: 2360: 2359: 2348: 2342: 2341: 2339: 2338: 2319: 2304: 2303: 2293: 2283: 2259: 2253: 2252: 2232: 2223: 2222: 2204: 2176: 2170: 2169: 2159: 2149: 2117: 2111: 2110: 2082: 2076: 2075: 2064: 2058: 2057: 2039: 2033: 2032: 2022: 1990: 1975: 1974: 1964: 1924: 1911: 1910: 1900: 1860: 1851: 1850: 1818: 1812: 1811: 1771: 1765: 1764: 1754: 1730: 1724: 1723: 1713: 1698:Applied Sciences 1688: 1677: 1676: 1658: 1634: 1628: 1627: 1617: 1607: 1583: 1577: 1576: 1568: 1562: 1561: 1533: 1524: 1523: 1513: 1503: 1479: 1473: 1472: 1454: 1430: 1424: 1421: 1415: 1402: 1393: 1376: 1370: 1369: 1367: 1354: 1346: 1340: 1339: 1327: 1321: 1320: 1310: 1304: 1303: 1301: 1300: 1285: 1279: 1278: 1258: 1252: 1251: 1231: 1225: 1224: 1206: 1193: 1192: 1148: 1142: 1141: 1131: 1099: 1093: 1092: 1066: 1057: 1051: 1050: 1048: 1028: 1013: 1012: 1010: 986: 980: 979: 969: 959: 927: 916: 915: 913: 889: 880: 879: 869: 859: 827: 184:meat-substitutes 88:world population 68:greenhouse gases 2710: 2709: 2705: 2704: 2703: 2701: 2700: 2699: 2670: 2669: 2654: 2649: 2636: 2635: 2631: 2616: 2612: 2575: 2571: 2556: 2552: 2537: 2533: 2518: 2514: 2505: 2503: 2490: 2489: 2485: 2476: 2474: 2459: 2455: 2446: 2444: 2431: 2430: 2426: 2413: 2412: 2408: 2395: 2394: 2387: 2372: 2363: 2350: 2349: 2345: 2336: 2334: 2321: 2320: 2307: 2260: 2256: 2249: 2233: 2226: 2177: 2173: 2118: 2114: 2083: 2079: 2066: 2065: 2061: 2054: 2040: 2036: 1991: 1978: 1925: 1914: 1861: 1854: 1819: 1815: 1772: 1768: 1731: 1727: 1689: 1680: 1635: 1631: 1584: 1580: 1569: 1565: 1534: 1527: 1480: 1476: 1431: 1427: 1422: 1418: 1412:Wayback Machine 1403: 1396: 1386:Wayback Machine 1377: 1373: 1365: 1352: 1348: 1347: 1343: 1328: 1324: 1311: 1307: 1298: 1296: 1287: 1286: 1282: 1275: 1259: 1255: 1248: 1232: 1228: 1221: 1207: 1196: 1149: 1145: 1100: 1096: 1064: 1058: 1054: 1037:PeerJ PrePrints 1029: 1016: 987: 983: 928: 919: 890: 883: 828: 821: 817: 799:Hydrogenotrophs 773:Purple bacteria 769:- Chicago-based 729:and subsidiary 717: 624: 598: 594: 590: 586: 582: 574: 567: 560: 556: 540:photoinhibition 537: 525: 519:microorganisms. 497: 252: 221: 211: 97: 56:water footprint 17: 12: 11: 5: 2708: 2698: 2697: 2692: 2687: 2682: 2668: 2667: 2653: 2652:External links 2650: 2648: 2647: 2629: 2610: 2569: 2550: 2531: 2512: 2483: 2453: 2424: 2406: 2385: 2361: 2343: 2305: 2254: 2247: 2224: 2195:(4): 341–356. 2171: 2112: 2093:(2): 150–158. 2077: 2059: 2052: 2034: 1976: 1912: 1875:(3): 643–647. 1852: 1813: 1766: 1725: 1678: 1649:(2): 184–196. 1629: 1578: 1563: 1544:(3): 199–202. 1525: 1474: 1445:(2): 265–278. 1425: 1416: 1394: 1371: 1341: 1322: 1305: 1280: 1273: 1253: 1246: 1226: 1219: 1194: 1143: 1094: 1075:(4): 287–291. 1052: 1014: 1001:(1): 195–222. 981: 917: 881: 818: 816: 813: 812: 811: 806: 801: 796: 791: 786: 781: 776: 770: 764: 759: 756: 753: 750: 744: 741: 738: 724: 716: 713: 712: 711: 704: 693: 690: 686: 631: 630: 626: 622: 619: 615: 611: 608:climate-change 604: 596: 592: 588: 584: 580: 572: 569: 565: 562: 558: 554: 543: 535: 523: 520: 516: 513: 509: 505: 496: 493: 492: 491: 490: 489: 482: 475: 468: 461: 454: 432: 431: 430: 423: 416: 411: 404: 397: 385: 384: 383: 378: 371: 364: 357: 350: 343: 336: 319: 318: 317: 310: 305: 302:Candida utilis 298: 291: 284: 277: 270: 251: 250:Microorganisms 248: 228:resilient food 219: 210: 207: 96: 93: 64:climate change 32:microorganisms 15: 9: 6: 4: 3: 2: 2707: 2696: 2695:Biotechnology 2693: 2691: 2688: 2686: 2683: 2681: 2678: 2677: 2675: 2665: 2660: 2656: 2655: 2643: 2639: 2633: 2625: 2621: 2614: 2606: 2602: 2597: 2592: 2588: 2584: 2580: 2573: 2565: 2561: 2554: 2546: 2542: 2535: 2527: 2523: 2516: 2502:on 2023-09-22 2501: 2497: 2493: 2487: 2472: 2468: 2464: 2457: 2442: 2438: 2434: 2433:"The Protein" 2428: 2420: 2416: 2410: 2402: 2398: 2392: 2390: 2381: 2377: 2370: 2368: 2366: 2357: 2353: 2347: 2332: 2328: 2324: 2318: 2316: 2314: 2312: 2310: 2301: 2297: 2292: 2287: 2282: 2277: 2273: 2269: 2265: 2258: 2250: 2248:9780849358661 2244: 2241:. CRC Press. 2240: 2239: 2231: 2229: 2220: 2216: 2212: 2208: 2203: 2198: 2194: 2190: 2186: 2182: 2181:Seitzinger SP 2175: 2167: 2163: 2158: 2153: 2148: 2143: 2139: 2135: 2131: 2127: 2123: 2116: 2108: 2104: 2100: 2096: 2092: 2088: 2081: 2073: 2069: 2063: 2055: 2049: 2045: 2038: 2030: 2026: 2021: 2016: 2012: 2008: 2005:(2): 100195. 2004: 2000: 1996: 1989: 1987: 1985: 1983: 1981: 1972: 1968: 1963: 1958: 1954: 1950: 1946: 1942: 1938: 1934: 1930: 1923: 1921: 1919: 1917: 1908: 1904: 1899: 1894: 1890: 1886: 1882: 1878: 1874: 1870: 1866: 1859: 1857: 1848: 1844: 1840: 1836: 1832: 1828: 1824: 1817: 1809: 1805: 1801: 1797: 1793: 1789: 1785: 1781: 1777: 1770: 1762: 1758: 1753: 1748: 1744: 1740: 1736: 1729: 1721: 1717: 1712: 1707: 1703: 1699: 1695: 1687: 1685: 1683: 1674: 1670: 1666: 1662: 1657: 1652: 1648: 1644: 1640: 1633: 1625: 1621: 1616: 1611: 1606: 1601: 1597: 1593: 1589: 1582: 1574: 1567: 1559: 1555: 1551: 1547: 1543: 1539: 1532: 1530: 1521: 1517: 1512: 1507: 1502: 1497: 1493: 1489: 1485: 1478: 1470: 1466: 1462: 1458: 1453: 1448: 1444: 1440: 1439:Food Security 1436: 1429: 1420: 1413: 1409: 1406: 1401: 1399: 1391: 1387: 1383: 1380: 1375: 1364: 1360: 1359: 1351: 1345: 1337: 1333: 1326: 1318: 1317: 1309: 1294: 1290: 1284: 1276: 1274:9789810215156 1270: 1266: 1265: 1257: 1249: 1243: 1239: 1238: 1230: 1222: 1216: 1212: 1205: 1203: 1201: 1199: 1190: 1186: 1182: 1178: 1174: 1170: 1166: 1162: 1158: 1154: 1147: 1139: 1135: 1130: 1125: 1121: 1117: 1113: 1109: 1105: 1098: 1090: 1086: 1082: 1078: 1074: 1070: 1063: 1056: 1047: 1042: 1038: 1034: 1027: 1025: 1023: 1021: 1019: 1009: 1004: 1000: 996: 992: 985: 977: 973: 968: 963: 958: 953: 949: 945: 941: 937: 933: 926: 924: 922: 912: 907: 903: 899: 895: 888: 886: 877: 873: 868: 863: 858: 853: 849: 845: 841: 837: 833: 826: 824: 819: 810: 807: 805: 802: 800: 797: 795: 792: 790: 787: 785: 784:NovoNutrients 782: 780: 777: 774: 771: 768: 767:Nature's Fynd 765: 763: 760: 757: 754: 751: 748: 745: 742: 739: 736: 732: 728: 725: 722: 719: 718: 709: 705: 702: 698: 694: 691: 687: 684: 680: 676: 672: 668: 667:kidney stones 664: 660: 656: 652: 648: 644: 640: 636: 635: 634: 627: 620: 616: 612: 609: 605: 602: 578: 570: 563: 552: 551:synthesis gas 548: 544: 541: 533: 532:reductive TCA 529: 521: 517: 514: 510: 506: 502: 501: 500: 488: 487: 483: 481: 480: 476: 474: 473: 469: 467: 466: 462: 460: 459: 455: 453: 451: 446: 443: 442: 440: 439:Cyanobacteria 436: 433: 429: 428: 424: 422: 421: 417: 415: 412: 410: 409: 405: 403: 402: 398: 396: 395: 391: 390: 389: 386: 382: 379: 377: 376: 372: 370: 369: 365: 363: 362: 358: 356: 355: 351: 349: 348: 344: 342: 341: 337: 335: 334: 330: 329: 327: 323: 320: 316: 315: 311: 309: 306: 304: 303: 299: 297: 296: 292: 290: 289: 285: 283: 282: 278: 276: 275: 271: 269: 268: 264: 263: 262: 261: 257: 256: 255: 247: 243: 239: 237: 233: 232:waste plastic 229: 225: 216: 206: 203: 201: 196: 194: 191: 190: 185: 181: 177: 175: 171: 167: 163: 158: 156: 151: 149: 145: 140: 138: 134: 129: 124: 122: 118: 114: 110: 106: 102: 92: 89: 84: 82: 77: 73: 69: 65: 61: 57: 53: 49: 45: 41: 37: 33: 29: 25: 21: 2642:the original 2632: 2624:BioSpace.com 2623: 2613: 2586: 2582: 2572: 2563: 2553: 2544: 2534: 2526:the original 2520:Spanoghe J. 2515: 2504:. 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Index

microorganisms
biomass
algae
yeasts
fungi
bacteria
water footprint
environmental degradation
climate change
greenhouse gases
ecological footprint
autotrophic
photovoltaic
world population
Max Delbrück
Germany
Denmark
fed-batch
batch
Food and Agriculture Organization of the United Nations
British Petroleum
Alfred Champagnat
Grangemouth Oil Refinery
Carroll L. Wilson
MIT
UNESCO Science Prize
Soviets
Kstovo
Kirishi
Quorn

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