557:
534:
38:
29:
1387:(called active metabolites 1 and 2) with half-lives of 14 and 16 hours, respectively. Peak plasma concentrations of active metabolites 1 and 2 are reached after three to four hours. The following metabolic pathway mainly results in two inactive conjugated and hydroxylated metabolites (called metabolites 5 and 6). Metabolites 5 and 6 are mainly excreted in the urine.
1595:
On
December 30, 2010, the FDA released a warning regarding "Fruta Planta" dietary products, which were found to contain undeclared amounts of sibutramine. The recall stated that "there is NO SAFE formula on the US market and that all versions of Fruta Planta contain sibutramine. All versions of the
1511:
Between
January 2003 and November 2005, a large randomized-controlled "Sibutramine Cardiovascular OUTcomes" (SCOUT) study with 10,742 patients examined whether or not sibutramine administered within a weight management program reduces the risk for cardiovascular complications in people at high risk
1584:
advised the public that illegal "Herbal Diet
Natural" had been found on the market, containing sibutramine, which is a prescription drug in Canada, without listing sibutramine as an ingredient. In October 2010 FDA notified consumers that "Slimming Beauty Bitter Orange Slimming Capsules contain the
1568:
An additional 34 products were recalled by the FDA on April 22, 2009, further underscoring the risks associated with unregulated "herbal supplements" to unsuspecting persons. This concern is especially relevant to those with underlying medical conditions incompatible with undeclared pharmaceutical
2448:
Jain DS, Subbaiah G, Sanyal M, Shrivastav PS, Pal U, Ghataliya S, et al. (2006). "Liquid chromatography/electrospray ionization tandem mass spectrometry validated method for the simultaneous quantification of sibutramine and its primary and secondary amine metabolites in human plasma and its
1599:
In 2011, some illegal weight loss products imported into
Ireland have been found to contain sibutramine. In 2012, similar concerns were raised in Australia, where illegal imported supplements have been found to contain sibutramine, resulting in public alerts from Australia's
1480:
In 1997, the US FDA approved it for weight loss and maintenance of weight loss in people with a BMI greater than or equal to 30 kg/m2 or for people with a BMI ≥27 kg/m2 who have other cardiovascular risk factors. It was manufactured and marketed by
1523:) said in a dissenting article, "Sibutramine: gone, but not forgotten", that the SCOUT study was flawed as it only covered high-risk patients and did not consider obese patients who did not have cardiovascular complications or similar contraindications.
852:
A history of coronary artery disease (e.g., angina, history of myocardial infarction), congestive heart failure, tachycardia, peripheral arterial occlusive disease, arrhythmia or cerebrovascular disease (stroke or transient ischemic attack
1002:
has been noted. (Fenfluramine, of the 1990s "Fen-Phen" combo, forced excess release of neurotransmitters—a different action. Phentermine was uninvolved in the rare—but clinically significant—heart issues of fenfluramine.)
2292:
Heal DJ, Aspley S, Prow MR, Jackson HC, Martin KF, Cheetham SC (August 1998). "Sibutramine: a novel anti-obesity drug. A review of the pharmacological evidence to differentiate it from d-amphetamine and d-fenfluramine".
2563:
3159:
944:
and heart rate in some patients, in the updated review in 2021 sibutramine was not included since the drug had been withdrawn from the market. When used, regular blood pressure monitoring needed to be performed.
2492:
Thevis M, Sigmund G, Schiffer AK, Schänzer W (2006). "Determination of N-desmethyl- and N-bisdesmethyl metabolites of
Sibutramine in doping control analysis using liquid chromatography-tandem mass spectrometry".
1540:
to voluntarily withdraw. Abbott announced the same day that it was withdrawing sibutramine from the US market, citing concerns over minimal efficacy coupled with increased risk of adverse cardiovascular events.
2975:
5428:
9625:
3126:
2060:
2056:
1533:
In August 2010 the FDA added a new contraindication for patients over 65 years of age because clinical studies of sibutramine did not include sufficient numbers of such patients.
2705:
1976:
Buckett WR, Thomas PC, Luscombe GP (1988). "The pharmacology of sibutramine hydrochloride (BTS 54 524), a new antidepressant which induces rapid noradrenergic down-regulation".
3019:"PRock Marketing, LLC Issues a Voluntary Nationwide Recall of All weight loss formulas and variation of formulas of Reduce Weight Fruta Planta/Reduce Weight Dietary Supplement"
2555:
3074:
2345:
Kim KA, Song WK, Park JY (November 2009). "Association of CYP2B6, CYP3A5, and CYP2C19 genetic polymorphisms with sibutramine pharmacokinetics in healthy Korean subjects".
3151:
7291:
1690:
1512:
for heart disease and concluded that use of silbutramine had a RR 1.16 for the primary outcome (composit of nonfatal MI, nonfatal CVA, cardiac arrest, and CV death).
7286:
1638:
1829:
9079:
1633:[Collegiate Board Resolution No. 784 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control] (in Brazilian Portuguese).
9645:
5120:
4225:
9074:
2267:
1610:
In a 2018 study the FDA found synthetic additives including sibutramine in over 700 diet supplements marketed as "natural", "traditional" or "herbal remedies".
759:
and sold under a variety of brand names including
Reductil, Meridia, Siredia, and Sibutrex before its withdrawal 2010 from most markets. It was classified as a
7346:
5463:
3185:
1027:. Sibutramine should not be taken within two weeks of stopping or starting an MAOI. Taking both sibutramine and certain medications used in the treatment of
155:
3095:
2967:
914:
has been observed in people taking sibutramine versus control (11.4% vs. 10.0%). In 2010 the FDA noted the concerns that sibutramine increases the risk of
1589:
3233:
2165:
Nisoli E, Carruba MO (October 2000). "An assessment of the safety and efficacy of sibutramine, an anti-obesity drug with a novel mechanism of action".
2891:
200:
1592:
in the UK issued a warning regarding "Payouji tea" and "Pai You Guo Slim
Capsules" which were found to contain undeclared quantities of sibutramine.
3045:
2745:
4111:
2728:
620:
6543:
4192:
3136:
1257:
701:
2032:
2945:
2778:
2638:
1585:
active pharmaceutical ingredient sibutramine, a prescription-only drug which is a stimulant. Sibutramine is not listed on the product label."
1659:
77:
2920:
2818:
7408:
6950:
6945:
6226:
6221:
6040:
5007:
4258:
3781:
3693:
2593:
634:
2413:
Glick SD, Haskew RE, Maisonneuve IM, Carlson JN, Jerussi TP (May 2000). "Enantioselective behavioral effects of sibutramine metabolites".
7798:
5113:
937:, upset stomach, constipation, trouble sleeping, dizziness, drowsiness, menstrual cramps/pain, headache, flushing, or joint/muscle pain.
9109:
9104:
8157:
8107:
6729:
2996:
1851:
9124:
9099:
1912:
1536:
On
October 8, 2010, the FDA recommended against continued prescribing because of unnecessary cardiovascular risks to patients, asking
849:
Existing damage on heart valves, coronary heart disease, congestive heart failure, serious arrhythmias, previous myocardial infarction
7843:
7838:
7833:
7828:
7818:
7813:
7808:
7803:
7793:
7783:
7773:
7753:
7743:
7738:
7733:
7548:
7488:
7326:
7067:
5458:
5453:
4009:
9119:
9114:
9094:
9089:
1043:, may also increase the risk for serotonin syndrome, as may the use of more than one serotonin reuptake inhibitor at the same time.
769:
As of 2018, the FDA still found sibutramine in over 700 diet supplements marketed as "natural", "traditional" or "herbal remedies".
7713:
7708:
7658:
7451:
3689:
1708:"Notification of Termination of Production, Sale, and Usage of Sibutramine Preparations and Their Active Pharmaceutical Ingredient"
2128:
1950:
1737:
7678:
7568:
7558:
7553:
4053:
3066:
8127:
5448:
5106:
3226:
3018:
9650:
8652:
5064:
3953:
2397:
1890:
1707:
1630:
1577:, the counterfeit drugs contain sibutramine, and at concentrations at least twice the amount recommended for weight loss.
9494:
7435:
4291:
1825:
1687:
9610:
8024:
5801:
4159:
1626:
1471:
760:
679:
221:
2260:
1326:(M2; BTS-54505), with much greater potency as monoamine reuptake inhibitors. Further studies have indicated that the (
9635:
9595:
8152:
8142:
8122:
3219:
3103:
654:
3182:
9605:
8662:
8480:
8147:
8132:
8117:
7900:
7250:
5081:
3970:
1601:
8775:
8475:
8425:
8137:
3639:
326:
185:
2941:
9215:
9084:
9069:
9064:
8647:
7455:
1500:, the FDA made no attempts to withdraw the drug, but was part of a Senate hearing in 2005. Similarly, in 2004,
402:
9059:
9054:
8642:
8637:
8402:
7481:
6511:
4002:
1631:"RDC Nº 784 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial"
1303:, and it has demonstrated antidepressant effects in animal models of depression. It was approved by the U.S.
2614:
Japsen B (13 March 2005). "FDA weighs decision on
Meridia; Health advisory likely for Abbott obesity drug".
9016:
8019:
7431:
5148:
5129:
2888:
2324:
1634:
1557:” for weight loss, that illegally contain undisclosed amounts of sibutramine. In March 2009, Dieter Müller
1550:
1501:
1304:
552:
453:
2815:"Consumer directed questions and answers about FDA's initiative against contaminated weight loss products"
9655:
9489:
8996:
8991:
8036:
6795:
6071:
4664:
4597:
3037:
2752:
2057:"Meridia (sibutramine hydrochloride): Follow-Up to an Early Communication about an Ongoing Safety Review"
1012:
956:, mental/mood changes (e.g., excitement, restlessness, confusion, depression, rare thoughts of suicide).
513:
1011:
Sibutramine has a number of clinically significant interactions. The concomitant use of sibutramine and
8627:
7505:
7497:
5790:
5302:
4427:
4335:
3697:
1094:
502:
357:
2024:
1688:
Health Canada
Endorsed Important Safety Information on MERIDIA (Sibutramine Hydrochloride Monohydrate)
1667:
8940:
8770:
4439:
3701:
2770:
2074:
Siebenhofer A, Winterholer S, Jeitler K, Horvath K, Berghold A, Krenn C, Semlitsch T (January 2021).
1666:. Therapeutic Goods Administration, Department of Health, Australian Government. 2010. Archived from
1607:
In October 2011, the FDA warned that 20 brands of dietary supplements were tainted with sibutramine.
1530:
recommended suspension of marketing authorizations for sibutramine based on the SCOUT study results.
1527:
857:
662:
InChI=1S/C17H26ClN/c1-13(2)12-16(19(3)4)17(10-5-11-17)14-6-8-15(18)9-7-14/h6-9,13,16H,5,10-12H2,1-4H3
7967:
2652:
James WP, Caterson ID, Coutinho W, Finer N, Van Gaal LF, Maggioni AP, et al. (September 2010).
744:, the United Kingdom, and the United States. However, the drug remains available in some countries.
9640:
9615:
7474:
3995:
3793:
3764:
3564:
1804:
1505:
1300:
705:
529:
2653:
2556:"FDA Drug Safety Communication: FDA Recommends Against the Continued Use of Meridia (sibutramine)"
732:
from the market in 2010 in several countries and regions including Australia, Canada, China, the
9006:
8965:
8689:
8557:
8552:
8542:
8470:
8460:
8214:
8204:
8187:
8046:
7268:
5069:
3958:
3804:
3242:
2912:
2814:
1762:
1485:. It was sold under a variety of brand names including Reductil, Meridia, Siredia, and Sibutrex.
1374:
1342:
136:
87:
59:
2630:
2585:
9166:
9134:
9043:
8682:
8450:
8087:
7996:
7988:
7980:
7972:
7447:
7443:
6850:
6126:
5556:
5509:
4904:
4375:
3430:
2817:. U.S. Food and Drug Administration Center for Drug Evaluation and Research. 22 December 2008.
1520:
1362:
1323:
1226:
1205:
1188:
1059:
999:
948:
The following side effects are infrequent but serious and require immediate medical attention:
844:
840:
that is not sufficiently controlled (e.g., >145/90 mmHg), caution in controlled hypertension
828:
725:
252:
9600:
9001:
8945:
8818:
8803:
8792:
8445:
8182:
8162:
6568:
6500:
5974:
5276:
4345:
2746:"European Medicines Agency recommends suspension of marketing authorisations for sibutramine"
1735:
1570:
1467:
1422:
1366:
1084:
1024:
926:
911:
393:
3004:
2261:"Meridia (sibutramine hydrochloride monohydrate) Capsules CIV. Full Prescribing Information"
1920:
1858:
1470:
after BASF/Knoll AG purchased the Boots Research Division in 1995. It was classified as a
352:
9322:
9181:
9176:
8833:
8823:
8813:
8677:
8465:
8417:
8362:
8352:
8102:
7439:
7311:
6840:
6384:
6116:
5546:
5525:
5137:
5024:
4939:
3534:
2458:
1857:(Press release). Food and Drug Administration of Thailand. October 20, 2010. Archived from
1697:: Subject: Voluntary withdrawal of Meridia (sibutramine) capsules from the Canadian market.
1474:
1319:
1168:
1147:
1130:
1104:
763:
697:
462:
287:
1330:)-enantiomers of each metabolite exert significantly stronger anorectic effects than the (
442:
8:
9630:
9590:
9484:
9230:
9033:
8980:
8632:
8547:
8537:
8485:
8455:
8391:
8278:
8209:
8199:
8082:
7125:
6970:
6835:
6563:
6420:
6246:
6111:
5766:
5541:
4850:
4790:
3814:
3600:
3479:
3451:
3281:
2997:"Press release: Warning over unlicensed herbal Payouji tea and Pai You Guo Slim Capsules"
2800:
1745:
1569:
adulterants. In January 2010, a similar alert was issued for counterfeit versions of the
1537:
1482:
1058:, may increase plasma levels of sibutramine. Sibutramine does not affect the efficacy of
756:
343:
143:
2968:"FDA Alert: Slimming Beauty Bitter Orange Slimming Capsules: Undeclared Drug Ingredient"
2842:"Chinese slimming capsules containing sibutramine sold over the Internet: a case series"
2462:
556:
533:
8843:
8838:
7940:
7210:
5236:
4041:
4037:
3899:
3545:
3474:
3361:
3206:
2866:
2841:
2518:
2370:
2320:
2234:
2209:
2190:
2132:
2100:
2075:
2001:
1942:
1565:" sold in Europe, containing as much as twice the dosage of the legally licensed drug.
1554:
1020:
949:
777:
Sibutramine has been used to produce appetite suppression for the purpose of attaining
147:
109:
3211:
3194:
2426:
1783:
128:
No human data exists; inconclusive evidence of teratogenic potential in animal studies
9620:
9171:
8918:
8908:
8878:
8808:
8500:
8243:
7915:
7201:
5939:
5646:
5221:
5041:
4943:
4462:
3873:
3351:
3346:
2871:
2686:
2510:
2474:
2430:
2393:
2362:
2302:
2239:
2182:
2178:
2105:
1993:
1989:
1562:
1516:
1426:
1373:
level after 1 hour and has also a half-life of 1 hour. Sibutramine is metabolized by
1315:
886:
721:
245:
101:
2586:"Petition to FDA to ban the diet drug sibutramine (MERIDIA) (HRG Publication #1613)"
2522:
2374:
2194:
2005:
8913:
8893:
8733:
8397:
8372:
8316:
7956:
7306:
7161:
6533:
5929:
5626:
5566:
5383:
5297:
5014:
4957:
4893:
4740:
3401:
3326:
3203:. Includes dosage information and a comprehensive list of international brand names
3022:
2861:
2853:
2720:
2676:
2668:
2654:"Effect of sibutramine on cardiovascular outcomes in overweight and obese subjects"
2502:
2466:
2422:
2354:
2229:
2221:
2174:
2095:
2091:
2087:
1985:
1508:
hearing that sibutramine may be more dangerous than the conditions it is used for.
1438:
1402:
1296:
force the release of these neurotransmitters rather than affecting their reuptake.
976:
892:
810:
798:
569:
231:
168:
37:
1284:; the serotonergic action, in particular, is thought to influence appetite. Older
9509:
9352:
9273:
8520:
8505:
8412:
8387:
8312:
8247:
8092:
8004:
7276:
7151:
7093:
7081:
6749:
6388:
6020:
5954:
5368:
5256:
5231:
4953:
4947:
4760:
4134:
3610:
3585:
3580:
3540:
3416:
3411:
3273:
3189:
2895:
2615:
1694:
1346:
863:
794:
709:
382:
270:
239:
5098:
4022:
1882:
9543:
9424:
9337:
8667:
8288:
7951:
7105:
7089:
7085:
7011:
6734:
6400:
6392:
6005:
5771:
5494:
5246:
5075:
4517:
4226:
4124:
4018:
3964:
3590:
3366:
2589:
1711:
1573:
weight loss drug Alli sold over the Internet. Instead of the active ingredient
1497:
1434:
1433:
g/L range in persons undergoing therapy with the drug. The parent compound and
1277:
1265:
941:
824:
733:
729:
2857:
2225:
9584:
9559:
9554:
9469:
9378:
9357:
9331:
9289:
9154:
8898:
8753:
8602:
8525:
8263:
7885:
7870:
7361:
7145:
7141:
7111:
7077:
7051:
7041:
6996:
6960:
6820:
6764:
6603:
6465:
6445:
6428:
6406:
6327:
6322:
6272:
6236:
6096:
6035:
5761:
5281:
5266:
5226:
4965:
4912:
4700:
4572:
4547:
4542:
4482:
4457:
3919:
3750:
3595:
3436:
3311:
2540:(8th ed.). Foster City, CA: Biomedical Publications. pp. 1426–1427.
2059:. United States Food and Drug Administration. 1 February 2010. Archived from
1749:
1741:
1581:
1489:
1396:
915:
898:
820:
545:
5378:
5373:
3067:"FDA Alert: Slim Xtreme Herbal Slimming Capsule: Undeclared Drug Ingredient"
20:
9549:
9464:
9342:
9297:
9245:
9186:
9144:
8883:
8530:
8308:
8303:
8253:
8234:
7910:
7296:
7191:
7181:
7006:
7001:
6845:
6815:
6703:
6573:
6451:
6363:
6332:
6287:
6282:
6277:
6121:
6091:
5979:
5888:
5848:
5751:
5671:
5561:
5551:
5363:
5358:
5343:
5338:
5317:
5010:
4998:
4908:
4815:
4745:
4735:
4587:
4577:
4477:
4472:
4395:
4390:
4370:
4355:
4309:
4071:
4035:
3789:
3745:
3615:
3560:
3555:
3441:
3376:
3306:
3291:
3268:
3250:
3199:
3152:"No Wonder It Works So Well: There May Be Viagra In That Herbal Supplement"
2875:
2690:
2514:
2478:
2434:
2366:
2243:
2186:
2109:
1852:"Thai FDA reveals voluntary withdrawal of sibutramine from the Thai market"
1370:
1341:, sibutramine and its metabolites have only low and likely inconsequential
1338:
1293:
1055:
1051:
940:
In a 2016 Cochrane review, sibutramine was found to substantially increase
837:
163:
6656:
Selective serotonin reuptake inhibitors and serotonin receptor modulators:
2672:
2358:
2306:
1997:
1281:
9569:
9534:
9504:
9434:
9429:
9404:
9302:
9205:
8858:
8848:
8828:
8782:
8763:
8743:
8722:
8495:
8430:
8382:
8322:
8293:
8273:
8239:
8167:
7961:
7895:
7366:
7356:
7301:
7272:
7222:
7166:
7119:
7101:
7036:
7016:
6965:
6930:
6890:
6885:
6830:
6800:
6779:
6769:
6759:
6719:
6658:
6638:
6628:
6608:
6588:
6548:
6538:
6485:
6414:
6396:
6368:
6353:
6312:
6292:
6241:
6206:
6166:
6161:
6106:
6076:
6055:
6045:
6030:
5995:
5959:
5924:
5853:
5843:
5833:
5828:
5776:
5756:
5721:
5701:
5631:
5606:
5581:
5576:
5571:
5536:
5531:
5489:
5484:
5433:
5241:
4928:
4825:
4690:
4625:
4620:
4610:
4567:
4552:
4537:
4527:
4497:
4487:
4360:
4330:
4325:
4271:
4248:
4243:
4215:
4172:
4149:
4139:
4081:
3987:
3909:
3845:
3840:
3770:
3760:
3755:
3740:
3729:
3724:
3654:
3625:
3550:
3520:
3489:
3464:
3426:
3381:
3341:
3331:
3301:
3296:
1786:(Press release). Ministry of Health and Family Welfare. February 10, 2011
1710:. sda.gov in People's Republic of China. October 30, 2010. Archived from
1493:
1399:
1289:
968:
953:
778:
737:
95:
2076:"Long-term effects of weight-reducing drugs in people with hypertension"
422:
9539:
9474:
9454:
9449:
9444:
9439:
9419:
9409:
9383:
9362:
9317:
9312:
9281:
9250:
9235:
9225:
9139:
8970:
8933:
8923:
8903:
8863:
8853:
8708:
8704:
8694:
8490:
8440:
8435:
8367:
8357:
8342:
8337:
8327:
8258:
8229:
8224:
8097:
8031:
8014:
7925:
7920:
7890:
7415:
7371:
7336:
7263:
7226:
7186:
7156:
7133:
7097:
7046:
7031:
6915:
6900:
6870:
6860:
6855:
6810:
6805:
6744:
6739:
6724:
6698:
6668:
6663:
6648:
6643:
6618:
6613:
6583:
6578:
6558:
6553:
6477:
6456:
6439:
6434:
6317:
6307:
6191:
6176:
6146:
6136:
6131:
6086:
6081:
6015:
6010:
5969:
5949:
5934:
5909:
5893:
5868:
5863:
5741:
5731:
5716:
5661:
5651:
5641:
5621:
5611:
5596:
5591:
5514:
5504:
5499:
5312:
5205:
5200:
5046:
5032:
5018:
4924:
4920:
4916:
4870:
4840:
4835:
4830:
4810:
4780:
4770:
4730:
4715:
4695:
4582:
4562:
4532:
4512:
4492:
4452:
4400:
4385:
4380:
4340:
4304:
4276:
4205:
4182:
4177:
4129:
4101:
4096:
4091:
4076:
4066:
3934:
3924:
3914:
3894:
3855:
3835:
3819:
3719:
3714:
3679:
3674:
3669:
3664:
3570:
3525:
3484:
3391:
3286:
2681:
2553:
1561:
published a study of sibutramine poisoning cases from similar Chinese "
1553:
issued an alert to consumers naming 27 different products marketed as “
1463:
1016:
984:
980:
807:
Patients with a history of or a predisposition to drug or alcohol abuse
752:
596:
433:
9519:
9414:
9327:
9307:
9240:
9129:
8960:
8928:
8873:
8868:
8377:
8347:
8298:
8283:
8219:
7946:
7905:
7536:
7531:
7526:
7521:
7516:
7403:
7351:
7321:
7316:
7236:
7218:
7214:
7171:
7129:
7072:
7021:
6940:
6910:
6774:
6693:
6683:
6678:
6673:
6598:
6593:
6473:
6469:
6358:
6348:
6297:
6216:
6186:
6050:
6000:
5919:
5914:
5883:
5878:
5838:
5736:
5726:
5691:
5616:
5586:
5519:
5479:
5443:
5348:
5333:
5307:
5271:
5261:
5190:
5185:
5180:
5175:
4934:
4820:
4755:
4750:
4725:
4720:
4710:
4705:
4615:
4557:
4522:
4502:
4467:
4423:
4281:
4238:
4210:
4144:
4086:
3904:
3889:
3865:
3734:
3659:
3649:
3605:
3530:
3494:
3469:
3459:
3406:
3356:
3321:
3259:
3246:
2803:(Press release). U.S. Food and Drug Administration. 22 December 2008.
2724:
2506:
2470:
1488:
In 2002, studies looked into reports of sudden death, heart failure,
1285:
1269:
934:
368:
308:
81:
4259:
4112:
3001:
United Kingdom Medicines & Healthcare Products Regulatory Agency
2073:
9524:
9370:
9210:
9191:
9021:
9011:
8955:
8950:
8888:
8758:
8748:
8738:
8515:
8407:
8332:
7880:
7390:
7341:
7331:
7230:
7176:
7137:
7115:
6905:
6895:
6688:
6481:
6424:
6410:
6181:
6171:
5873:
5858:
5823:
5681:
5676:
5666:
5636:
5438:
5195:
4685:
4641:
4365:
4350:
4193:
3929:
3850:
3575:
3515:
3421:
3386:
3371:
3336:
1763:"De-registration of pharmaceutical products containing sibutramine"
1574:
1459:
1418:
1273:
1261:
1032:
1028:
972:
882:
870:
748:
741:
482:
413:
7466:
619:
334:
1-(1-(4-chlorophenyl)cyclobutyl)-N,N,2,2-tetramethylpropan-1-amine
9564:
9529:
9459:
9220:
8622:
8587:
8268:
8192:
8177:
7823:
7788:
7778:
7768:
7763:
7758:
7748:
7196:
7026:
6979:
6975:
6925:
6920:
6875:
6865:
6825:
6754:
6633:
6302:
6255:
6251:
6201:
6196:
6151:
6141:
6101:
6025:
5944:
5706:
5696:
5686:
5656:
5601:
5423:
5418:
5413:
5408:
5403:
5398:
5393:
5353:
5251:
5170:
4507:
3709:
3498:
3316:
2916:
1596:
formula are UNSAFE and should not be purchased from any source."
1544:
1377:
1369:, reducing its bioavailability. The drug itself reaches its peak
1311:
1036:
988:
960:
919:
875:
717:
713:
2295:
International Journal of Obesity and Related Metabolic Disorders
1978:
Progress in Neuro-Psychopharmacology & Biological Psychiatry
1276:(by ~16%), thereby increasing the levels of these substances in
9479:
9399:
9264:
9255:
9196:
8699:
8617:
8607:
8597:
8582:
8572:
8567:
8172:
8072:
7875:
7853:
7848:
7728:
7723:
7718:
7703:
7698:
7693:
7668:
7633:
7628:
7623:
7618:
7613:
7608:
7603:
7206:
6935:
6880:
6623:
6461:
6211:
6156:
5964:
5711:
5388:
4231:
Tooltip Noradrenergic and specific serotonergic antidepressants
4054:
1429:. Plasma levels of these three species are usually in the 1–10
1380:
1047:
1040:
964:
930:
493:
279:
3207:
U.S. Food and Drug Administration (FDA) product safety website
2839:
2155:
Cloridrato de sibutramina monoidratado. Bula. . Medley (2007).
28:
9514:
8672:
8592:
8562:
8112:
8062:
8057:
7930:
7858:
7683:
7648:
7588:
7573:
4422:
3939:
3131:
2899:
2751:. European Medicines Agency. January 21, 2010. Archived from
2491:
2412:
1384:
992:
802:
700:
which has been discontinued in many countries. It works as a
610:
275:
3127:"'Natural' diet pills tainted with banned prescription drug"
3021:. United States Food and Drug Administration. Archived from
2447:
518:
9026:
8657:
8612:
8577:
8077:
8067:
7863:
7688:
7673:
7663:
7653:
7643:
7638:
7598:
7593:
7583:
7578:
7563:
7543:
7280:
4292:
3396:
1046:
The concomitant use of sibutramine and drugs which inhibit
473:
5802:
4160:
2651:
2390:
Pharmacotherapy of obesity : options and alternatives
1492:
and gastrointestinal problems. Despite a 2002 petition by
708:. Until 2010, it was widely marketed and prescribed as an
9499:
2051:
2049:
1807:(Press release). MedSafe in New Zealand. October 11, 2010
1734:
Sibutramin-Vertrieb in der Europäischen Union ausgesetzt
7251:
3102:. Australian Government. 9 November 2012. Archived from
1765:(Press release). info.gov in Hong Kong. November 2, 2010
1383:
into two pharmacologically active primary and secondary
3241:
2840:
Müller D, Weinmann W, Hermanns-Clausen M (March 2009).
2266:. Abbott Laboratories, North Chicago, IL 60064, U.S.A.
6793:
Serotonin–norepinephrine–dopamine reuptake inhibitors:
6069:
Serotonin–norepinephrine–dopamine reuptake inhibitors:
2554:
Center for Drug Evaluation and Research (2019-06-28).
2046:
922:
in patients with a history of cardiovascular disease.
9626:
Serotonin–norepinephrine–dopamine reuptake inhibitors
6512:
2801:"FDA warns consumers about tainted weight loss pills"
2291:
1975:
1805:"Withdrawal of Sibutramine (Reductil) in New Zealand"
1395:
Sibutramine has usually been used in the form of the
1337:
Unlike other serotonergic appetite suppressants like
1307:(FDA) in November 1997 for the treatment of obesity.
963:, problems urinating, abnormal bruising or bleeding,
5149:
4264:
Tooltip Serotonin antagonist and reuptake inhibitors
4117:
Tooltip Serotonin–norepinephrine reuptake inhibitors
2583:
4598:
4198:
Tooltip Norepinephrine–dopamine reuptake inhibitors
2584:Wolfe SM, Sasich LD, Barbehenn E (March 19, 2002).
1826:"FDA warns online sellers of banned slimming pills"
1019:) is not indicated, as it may increase the risk of
959:Symptoms that require urgent medical attention are
401:
5791:
1660:"Sibutramine (Reductil) - withdrawal in Australia"
1441:is generally present at concentrations of >200
1095:
929:are: dry mouth, paradoxically increased appetite,
5128:
4440:
2019:
2017:
2015:
1453:
789:Sibutramine is contraindicated in patients with:
9582:
4663:
1458:Sibutramine was originally developed in 1988 by
1299:Sibutramine's mechanism of action is similar to
747:Sibutramine was originally developed in 1988 by
381:
5000:
4059:Tooltip Selective serotonin reuptake inhibitors
2538:Disposition of Toxic Drugs and Chemicals in Man
2210:"Serotonergic drugs and valvular heart disease"
1913:"Abbott Pulls Diet Drug Meridia Off US Shelves"
351:
9646:World Anti-Doping Agency prohibited substances
2768:
2207:
2012:
1971:
1969:
1967:
1883:"Top obesity drug sibutramine being suspended"
1545:Counterfeit weight-loss products, 2008–present
813:to the drug or any of the inactive ingredients
7482:
6717:Serotonin–norepinephrine reuptake inhibitors:
6501:
5993:Serotonin–norepinephrine reuptake inhibitors:
5821:Selective norepinephrine reuptake inhibitors:
5114:
4003:
3227:
3096:"Majestic slimming capsules: Safety advisory"
2164:
2129:"Meridia Side Effects, and Drug Interactions"
1910:
1417:-demethylated metabolites may be measured in
1085:
736:, Hong Kong, India, Mexico, New Zealand, the
5907:Norepinephrine–dopamine reuptake inhibitors:
5138:
2913:"Fake Alli diet pills can pose health risks"
2645:
2485:
2441:
2381:
2201:
2158:
1105:
5034:
4851:
4791:
4297:Tooltip Serotonin modulator and stimulators
2771:"Abbott Labs Withdraws Meridia From Market"
2344:
2338:
2321:"FDA APPROVES SIBUTRAMINE TO TREAT OBESITY"
2080:The Cochrane Database of Systematic Reviews
1964:
1408:
1258:serotonin–norepinephrine reuptake inhibitor
816:Patients below 18 and above 65 years of age
781:in the treatment of patients with obesity.
702:serotonin–norepinephrine reuptake inhibitor
7489:
7475:
5807:Tooltip Norepinephrine reuptake inhibitors
5121:
5107:
4165:Tooltip Norepinephrine reuptake inhibitors
4017:
4010:
3996:
3234:
3220:
3183:Abbott Press Release on Meridia Withdrawal
2549:
2547:
1504:, FDA "whistleblower", testified before a
831:active drugs, particularly other anoretics
555:
532:
441:
257:97%, (94% for its desmethyl metabolites, M
2865:
2680:
2451:Rapid Communications in Mass Spectrometry
2233:
2123:
2121:
2119:
2099:
1935:
1911:Rockoff JD, Dooren JC (October 8, 2010).
461:
7256:Tooltip Vesicular monoamine transporters
6531:Selective serotonin reuptake inhibitors:
4892:
2449:application to a bioequivalence study".
2387:
2025:"The FDA August 2010 drug safety update"
1549:On December 22, 2008, the United States
724:. It has been associated with increased
3124:
2544:
1437:are often not detectable in urine, but
755:, UK, and manufactured and marketed by
528:
421:
100:
9583:
2942:"Herbal diet product poses heart risk"
2706:"Sibutramine: gone, but not forgotten"
2703:
2613:
2535:
2347:Clinical Pharmacology and Therapeutics
2116:
1664:Therapeutic Goods Administration (Tga)
1625:
1448:
1361:Sibutramine is well absorbed from the
834:History of peripheral arterial disease
546:
7470:
6517:Tooltip Serotonin reuptake inhibitors
5102:
4987:
4891:
4662:
4421:
4034:
3991:
3215:
3149:
2495:European Journal of Mass Spectrometry
2273:from the original on 17 February 2017
2255:
2253:
1832:from the original on January 15, 2014
801:, serious depression or pre-existing
692:, formerly sold under the brand name
642:ClC1=CC=C(C2(CCC2)C(CC(C)C)N(C)C)C=C1
501:
215:
86:
5154:Tooltip Dopamine reuptake inhibitors
3038:"Seizures of illegal medicines rise"
2285:
1260:(SNRI) that, in humans, reduces the
784:
167:
9495:Lysergic acid 2,4-dimethylazetidide
7496:
4603:Tooltip Tetracyclic antidepressants
2948:from the original on March 28, 2010
2781:from the original on March 28, 2017
2661:The New England Journal of Medicine
2631:"Insider: FDA Won't Protect Public"
2301:(Suppl 1): S18-28, discussion S29.
2208:Rothman RB, Baumann MH (May 2009).
1904:
1356:
1070:
481:
372:
13:
6851:Didesmethylsibutramine (BTS-54505)
6127:Didesmethylsibutramine (BTS-54505)
5796:Tooltip Norepinephrine transporter
5557:Didesmethylsibutramine (BTS-54505)
2846:Deutsches Ärzteblatt International
2821:from the original on 17 March 2009
2769:Andrew Pollack (October 8, 2010).
2501:(2). Chichester, England: 129–36.
2250:
2131:. RxList.com. 2007. Archived from
1365:(77%), but undergoes considerable
1100:Tooltip Norepinephrine transporter
211:: Withdrawn from market
14:
9667:
5369:Etybenzatropine (ethybenztropine)
4988:
4445:Tooltip Tricyclic antidepressants
3176:
3003:. 20 October 2010. Archived from
2641:from the original on 19 May 2006.
901:women (relative contraindication)
295:1 hour (sibutramine), 14 hours (M
120:
6841:Desmethylsibutramine (BTS-54354)
6117:Desmethylsibutramine (BTS-54354)
5547:Desmethylsibutramine (BTS-54354)
3100:Therapeutic Goods Administration
3035:
2889:34 weight loss products recalled
2415:European Journal of Pharmacology
2179:10.1046/j.1467-789x.2000.00020.x
1752:2010-01-21. Retrieved 2010-01-27
1602:Therapeutic Goods Administration
1310:Sibutramine is reported to be a
589:
586:
580:
36:
27:
8426:N,alpha-Diethylphenylethylamine
7452:Monoamine metabolism modulators
3162:from the original on 2018-10-13
3143:
3118:
3088:
3077:from the original on 2018-08-25
3059:
3048:from the original on 2012-10-24
3029:
3011:
2989:
2978:from the original on 2018-08-25
2960:
2934:
2923:from the original on 2010-01-25
2905:
2882:
2833:
2807:
2793:
2762:
2738:
2697:
2622:
2618:. Chicago, Illinois. p. 1.
2607:
2596:from the original on 2006-12-19
2577:
2566:from the original on 2022-12-12
2529:
2406:
2313:
2146:
2067:
2035:from the original on 2017-01-12
1953:from the original on 2017-10-08
1893:from the original on 2010-01-25
1875:
1844:
1641:from the original on 2023-08-03
1413:Sibutramine and its two active
1065:
1006:
905:
772:
667:Key:UNAANXDKBXWMLN-UHFFFAOYSA-N
2392:. Boca Raton, Fla: CRC Press.
2092:10.1002/14651858.CD007654.pub5
1818:
1797:
1776:
1755:
1725:
1700:
1681:
1652:
1619:
1454:Regulatory approval, 1997–2010
1076:Sibutramine (and metabolites)
1023:, a somewhat rare but serious
574:
207:
194:
1:
7432:Receptor/signaling modulators
6506:Tooltip Serotonin transporter
5130:Monoamine reuptake inhibitors
3125:Carroll L (19 October 2011).
2628:Hearing of 17 November 2004.
2427:10.1016/s0014-2999(00)00216-8
2214:Expert Opinion on Drug Safety
1613:
1090:Tooltip Serotonin transporter
819:Concomitant treatment with a
244:Absorption 77%, considerable
9651:Withdrawn anti-obesity drugs
6346:Tetracyclic antidepressants:
5143:Tooltip Dopamine transporter
4665:Monoamine oxidase inhibitors
3195:Sibutramine drug information
2944:. CBC News. March 26, 2010.
2325:Food and Drug Administration
1990:10.1016/0278-5846(88)90003-6
1551:Food and Drug Administration
1390:
1305:Food and Drug Administration
1110:Tooltip Dopamine transporter
1013:monoamine oxidase inhibitors
7:
9490:Lysergic acid 2-butyl amide
6796:3,3-Diphenylcyclobutanamine
6072:3,3-Diphenylcyclobutanamine
4859:Tooltip Monoamine oxidase B
4799:Tooltip Monoamine oxidase A
4428:tetracyclic antidepressants
3150:Cohen R (12 October 2018).
889:(relative contraindication)
10:
9672:
9500:Lysergic acid diethylamide
7436:Monoamine releasing agents
6994:Tricyclic antidepressants:
6270:Tricyclic antidepressants:
5339:Benzatropine (benztropine)
4336:Dextromethorphan/bupropion
935:strange taste in the mouth
866:(overactive thyroid gland)
793:Psychiatric conditions as
564:Chemical and physical data
48:)-(−)-sibutramine (bottom)
9611:Drugs developed by AbbVie
9392:
9153:
9042:
8979:
8791:
8721:
8045:
7504:
7424:
7380:
7249:
7060:
6989:
6788:
6712:
6526:
6499:
6377:
6341:
6265:
6064:
5988:
5902:
5816:
5789:
5472:
5326:
5290:
5214:
5163:
5136:
5059:
4994:
4983:
4900:
4887:
4849:
4789:
4675:
4671:
4658:
4634:
4596:
4438:
4434:
4417:
4318:
4290:
4257:
4224:
4191:
4158:
4110:
4052:
4048:
4030:
3948:
3882:
3864:
3828:
3803:
3780:
3688:
3638:
3508:
3450:
3267:
3258:
2858:10.3238/arztebl.2009.0218
2226:10.1517/14740330902931524
1943:"Sibutramine - Drugs.com"
1528:European Medicines Agency
1526:On January 21, 2010, the
1301:tricyclic antidepressants
1245:
858:transient ischemic attack
728:and strokes and has been
675:
650:
630:
608:
595:
568:
563:
544:
512:
492:
472:
452:
432:
412:
392:
367:
342:
322:
317:
307:
286:
269:
251:
238:
230:
184:
179:
154:
135:
108:
94:
76:
68:
58:
53:
35:
26:
9636:Substituted amphetamines
9596:4-Chlorophenyl compounds
8390:(Dextromethamphetamine,
6720:Atomoxetine (tomoxetine)
5996:Atomoxetine (tomoxetine)
5042:Rubidium chloride (RbCl)
1637:(published 2023-04-04).
1506:Senate Finance Committee
1409:Detection in body fluids
1231:)-Didesmethylsibutramine
1210:)-Didesmethylsibutramine
706:tricyclic antidepressant
9606:Dimethylamino compounds
9044:Phenylalkylpyrrolidines
8966:Methylenedioxycathinone
8643:3,4-MDA (tenamfetamine)
7098:mepyramine (pyrilamine)
4905:Atypical antipsychotics
2704:Haslam D (April 2010).
1917:The Wall Street Journal
1635:Diário Oficial da União
1466:, UK,/ and marketed by
925:Frequently encountered
726:cardiovascular diseases
313:Urine (77%), feces (8%)
7968:β-Methylphenethylamine
7962:α-Methylphenethylamine
7372:Vanoxerine (GBR-12909)
7219:pethidine (meperidine)
6474:pethidine (meperidine)
5262:Pethidine (meperidine)
2323:(Press release). U.S.
1521:National Obesity Forum
1477:in the United States.
1363:gastrointestinal tract
1324:didesmethylsibutramine
1189:Didesmethylsibutramine
1173:)-Desmethylsibutramine
1152:)-Desmethylsibutramine
1060:hormonal contraception
1000:pulmonary hypertension
998:Currently, no case of
845:pulmonary hypertension
766:in the United States.
9159:(and close relatives)
8658:MDMA (midomafetamine)
8000:-Methylphenethylamine
7992:-Methylphenethylamine
7984:-Methylphenethylamine
7976:-Methylphenethylamine
7456:Monoamine neurotoxins
7022:Dosulepin (dothiepin)
6569:Didesmethylcitalopram
6298:Dosulepin (dothiepin)
5975:Serdexmethylphenidate
5277:Serdexmethylphenidate
3829:Absorption inhibitors
2673:10.1056/NEJMoa1003114
2359:10.1038/clpt.2009.145
1468:Knoll Pharmaceuticals
1423:liquid chromatography
1367:first-pass metabolism
1025:adverse drug reaction
912:cardiovascular events
246:first-pass metabolism
9323:N,N-Dimethyldopamine
8981:Phenylisobutylamines
8678:Naphthylaminopropane
8363:Isopropylamphetamine
8353:4-Hydroxyamphetamine
7347:Methoxytetrabenazine
7312:Dihydrotetrabenazine
7126:Arylcyclohexylamines
6421:Arylcyclohexylamines
5572:Dizocilpine (MK-801)
5526:Chaenomeles speciosa
5227:Benocyclidine (BTCP)
5026:Hypericum perforatum
4894:Adjunctive therapies
2919:. January 23, 2010.
2637:. 19 November 2004.
1828:. January 12, 2014.
1588:In October 2010 the
1483:Abbott Laboratoriess
1475:controlled substance
1322:(M1; BTS-54354) and
1320:desmethylsibutramine
1280:and helping enhance
1131:Desmethylsibutramine
764:controlled substance
712:in the treatment of
698:appetite suppressant
696:among others, is an
16:Appetite suppressant
9485:Lysergic acid amide
9231:Ethylnorepinephrine
9034:Phenylisobutylamine
8486:Phenylpropanolamine
8421:-Norpseudoephedrine
8392:Levomethamphetamine
8279:Dimethylamphetamine
6971:Threohydrobupropion
6836:Desmethylsertraline
6564:Desmethylcitalopram
6247:Threohydrobupropion
6112:Desmethylsertraline
5767:Threohydrobupropion
5542:Desmethylsertraline
4042:receptor modulators
4038:reuptake inhibitors
3601:Phenylpropanolamine
3480:Levopropylhexedrine
3452:Adrenergic agonists
3282:4-Methylamphetamine
3139:on 11 January 2012.
3007:on 9 February 2012.
2463:2006RCMS...20.3509J
2388:Hofbauer K (2004).
2327:. November 24, 1997
1746:Abbott Laboratories
1555:dietary supplements
1538:Abbott Laboratories
1449:Society and culture
1077:
987:, abnormal vision,
950:cardiac arrhythmias
910:A higher number of
881:Enlargement of the
757:Abbott Laboratories
360:(chlorosibutramine)
299:) & 16 hours (M
23:
9656:Isobutyl compounds
7941:Phenylethanolamine
7211:dextropropoxyphene
5237:Dexmethylphenidate
5086:Never to phase III
3975:Never to phase III
3900:Desiccated thyroid
3546:Dexmethylphenidate
3243:Antiobesity agents
3188:2011-09-27 at the
2894:2009-04-26 at the
2775:The New York Times
2063:on 6 January 2012.
1923:on 11 October 2010
1784:"Banned Medicines"
1693:2013-01-11 at the
1563:herbal supplements
1316:active metabolites
1075:
1021:serotonin syndrome
42:Sibutramine (top),
19:
9578:
9577:
8919:N-Ethylpentedrone
8879:Dimethylcathinone
8501:Propylamphetamine
8244:Dextroamphetamine
7916:Methallylescaline
7464:
7463:
7459:
7245:
7244:
6520:
6495:
6494:
5940:Levophacetoperane
5810:
5785:
5784:
5647:Levophacetoperane
5222:4-Fluoropethidine
5157:
5096:
5095:
5055:
5054:
5028:(St. John's Wort)
4979:
4978:
4944:lithium carbonate
4883:
4882:
4879:
4878:
4654:
4653:
4650:
4649:
4463:Amitriptylinoxide
4413:
4412:
4409:
4408:
3985:
3984:
3874:2,4-Dinitrophenol
3807:receptor agonists
3702:glucagon agonists
3634:
3633:
3352:Dimethylcathinone
3347:Dextroamphetamine
3025:on 23 March 2012.
2536:Baselt R (2008).
2457:(23): 3509–3521.
2399:978-0-415-30321-7
1519:(chairman of the
1427:mass spectrometry
1256:Sibutramine is a
1254:
1253:
887:urinary retention
785:Contraindications
687:
686:
621:Interactive image
514:CompTox Dashboard
219:
210:
203:(Anorectic drugs)
198:
124:
9663:
9284:
9276:
9267:
9258:
9199:
9160:
8914:N-Ethylhexedrone
8894:Hydroxybupropion
8734:Chlorphentermine
8711:
8420:
8398:Methoxyphenamine
8373:Lisdexamfetamine
8317:Levofenfluramine
7957:Phenpromethamine
7491:
7484:
7477:
7468:
7467:
7426:
7413:Antagonist-like:
7307:Deutetrabenazine
7257:
7253:
7197:MIN-117 (WF-516)
7162:Dextromethorphan
6534:6-Nitroquipazine
6524:
6523:
6518:
6514:
6509:
6507:
6503:
5930:Hydroxybupropion
5814:
5813:
5808:
5804:
5799:
5797:
5793:
5687:MIN-117 (WF-516)
5627:Hydroxybupropion
5567:Diphenylpyraline
5298:Diphenylprolinol
5161:
5160:
5155:
5151:
5146:
5144:
5140:
5123:
5116:
5109:
5100:
5099:
5036:
5002:
4985:
4984:
4958:triiodothyronine
4954:Thyroid hormones
4889:
4888:
4860:
4856:
4800:
4796:
4741:Phenoxypropazine
4673:
4672:
4660:
4659:
4604:
4600:
4446:
4442:
4436:
4435:
4419:
4418:
4298:
4294:
4265:
4261:
4232:
4228:
4199:
4195:
4166:
4162:
4118:
4114:
4060:
4056:
4050:
4049:
4032:
4031:
4012:
4005:
3998:
3989:
3988:
3402:Lisdexamfetamine
3327:Chlorphentermine
3265:
3264:
3236:
3229:
3222:
3213:
3212:
3171:
3170:
3168:
3167:
3147:
3141:
3140:
3135:. Archived from
3122:
3116:
3115:
3113:
3111:
3092:
3086:
3085:
3083:
3082:
3063:
3057:
3056:
3054:
3053:
3033:
3027:
3026:
3015:
3009:
3008:
2993:
2987:
2986:
2984:
2983:
2964:
2958:
2957:
2955:
2953:
2938:
2932:
2931:
2929:
2928:
2909:
2903:
2902:, 22 April 2009.
2886:
2880:
2879:
2869:
2837:
2831:
2830:
2828:
2826:
2811:
2805:
2804:
2797:
2791:
2790:
2788:
2786:
2766:
2760:
2759:
2757:
2750:
2742:
2736:
2735:
2734:on 26 July 2015.
2733:
2727:. Archived from
2725:10.1002/pdi.1453
2710:
2701:
2695:
2694:
2684:
2658:
2649:
2643:
2642:
2626:
2620:
2619:
2611:
2605:
2604:
2602:
2601:
2581:
2575:
2574:
2572:
2571:
2551:
2542:
2541:
2533:
2527:
2526:
2507:10.1255/ejms.797
2489:
2483:
2482:
2471:10.1002/rcm.2760
2445:
2439:
2438:
2410:
2404:
2403:
2385:
2379:
2378:
2342:
2336:
2335:
2333:
2332:
2317:
2311:
2310:
2289:
2283:
2282:
2280:
2278:
2272:
2265:
2257:
2248:
2247:
2237:
2205:
2199:
2198:
2162:
2156:
2154:
2150:
2144:
2143:
2141:
2140:
2125:
2114:
2113:
2103:
2071:
2065:
2064:
2053:
2044:
2043:
2041:
2040:
2021:
2010:
2009:
1973:
1962:
1961:
1959:
1958:
1939:
1933:
1932:
1930:
1928:
1919:. Archived from
1908:
1902:
1901:
1899:
1898:
1879:
1873:
1872:
1870:
1869:
1863:
1856:
1848:
1842:
1841:
1839:
1837:
1822:
1816:
1815:
1813:
1812:
1801:
1795:
1794:
1792:
1791:
1780:
1774:
1773:
1771:
1770:
1759:
1753:
1733:
1729:
1723:
1722:
1720:
1719:
1704:
1698:
1685:
1679:
1678:
1676:
1675:
1656:
1650:
1649:
1647:
1646:
1623:
1571:over-the-counter
1439:dinorsibutramine
1357:Pharmacokinetics
1111:
1107:
1101:
1097:
1091:
1087:
1078:
1074:
1071:Pharmacodynamics
1015:(MAOIs, such as
893:Pheochromocytoma
811:Hypersensitivity
799:anorexia nervosa
683:
682:
623:
603:
591:
588:
582:
576:
559:
548:
537:
536:
522:
520:
505:
485:
465:
445:
425:
405:
385:
375:
374:
355:
291:
217:
214:
209:
206:
196:
193:
171:
122:
119:
104:
90:
40:
31:
24:
22:
18:
9671:
9670:
9666:
9665:
9664:
9662:
9661:
9660:
9641:Withdrawn drugs
9616:Phenethylamines
9581:
9580:
9579:
9574:
9510:Methoxphenidine
9388:
9353:Normetanephrine
9282:
9274:
9265:
9256:
9197:
9158:
9157:
9149:
9038:
9029:
8975:
8936:
8787:
8778:
8766:
8717:
8709:
8685:
8533:
8521:Tranylcypromine
8506:Pseudoephedrine
8418:
8413:Norfenfluramine
8388:Methamphetamine
8313:Dexfenfluramine
8248:Levoamphetamine
8195:
8093:Bromo-DragonFLY
8041:
8027:
8005:Methylphenidate
7936:
7506:Phenethylamines
7500:
7498:Phenethylamines
7495:
7465:
7460:
7420:
7398:DAT modulators:
7376:
7277:methamphetamine
7255:
7241:
7152:Cyclobenzaprine
7094:diphenhydramine
7082:brompheniramine
7056:
6985:
6784:
6750:Levomilnacipran
6708:
6516:
6508:
6505:
6491:
6389:brompheniramine
6373:
6337:
6261:
6060:
6021:Levomilnacipran
5984:
5955:Methylphenidate
5898:
5806:
5798:
5795:
5781:
5468:
5322:
5286:
5257:Methylphenidate
5232:Desoxypipradrol
5210:
5153:
5145:
5142:
5132:
5127:
5097:
5092:
5091:
5076:Clinical trials
5051:
4990:
4975:
4971:
4963:
4948:lithium citrate
4896:
4875:
4858:
4855:
4845:
4798:
4795:
4785:
4761:Tranylcypromine
4667:
4646:
4630:
4602:
4592:
4444:
4430:
4405:
4314:
4296:
4286:
4263:
4253:
4230:
4220:
4197:
4187:
4164:
4154:
4135:Levomilnacipran
4116:
4106:
4058:
4044:
4026:
4019:Antidepressants
4016:
3986:
3981:
3980:
3965:Clinical trials
3944:
3878:
3860:
3824:
3806:
3799:
3776:
3700:
3684:
3641:
3630:
3611:Propylhexedrine
3586:Phendimetrazine
3581:Methylphenidate
3541:Dexfenfluramine
3504:
3446:
3417:Norfenfluramine
3412:Methamphetamine
3274:phenethylamines
3272:
3254:
3240:
3190:Wayback Machine
3179:
3174:
3165:
3163:
3148:
3144:
3123:
3119:
3109:
3107:
3094:
3093:
3089:
3080:
3078:
3065:
3064:
3060:
3051:
3049:
3042:The Irish Times
3034:
3030:
3017:
3016:
3012:
2995:
2994:
2990:
2981:
2979:
2966:
2965:
2961:
2951:
2949:
2940:
2939:
2935:
2926:
2924:
2911:
2910:
2906:
2896:Wayback Machine
2887:
2883:
2852:(13): 218–222.
2838:
2834:
2824:
2822:
2813:
2812:
2808:
2799:
2798:
2794:
2784:
2782:
2767:
2763:
2755:
2748:
2744:
2743:
2739:
2731:
2708:
2702:
2698:
2667:(10): 905–917.
2656:
2650:
2646:
2629:
2627:
2623:
2616:Chicago Tribune
2612:
2608:
2599:
2597:
2582:
2578:
2569:
2567:
2552:
2545:
2534:
2530:
2490:
2486:
2446:
2442:
2411:
2407:
2400:
2386:
2382:
2343:
2339:
2330:
2328:
2319:
2318:
2314:
2290:
2286:
2276:
2274:
2270:
2263:
2259:
2258:
2251:
2206:
2202:
2167:Obesity Reviews
2163:
2159:
2153:(in Portuguese)
2152:
2151:
2147:
2138:
2136:
2127:
2126:
2117:
2086:(1): CD007654.
2072:
2068:
2055:
2054:
2047:
2038:
2036:
2023:
2022:
2013:
1974:
1965:
1956:
1954:
1941:
1940:
1936:
1926:
1924:
1909:
1905:
1896:
1894:
1881:
1880:
1876:
1867:
1865:
1861:
1854:
1850:
1849:
1845:
1835:
1833:
1824:
1823:
1819:
1810:
1808:
1803:
1802:
1798:
1789:
1787:
1782:
1781:
1777:
1768:
1766:
1761:
1760:
1756:
1731:
1730:
1726:
1717:
1715:
1706:
1705:
1701:
1695:Wayback Machine
1686:
1682:
1673:
1671:
1658:
1657:
1653:
1644:
1642:
1624:
1620:
1616:
1547:
1515:In April 2010
1456:
1451:
1411:
1393:
1375:cytochrome P450
1359:
1350:
1334:)-enantiomers.
1288:agents such as
1278:synaptic clefts
1272:(by ~54%), and
1249:
1109:
1099:
1089:
1073:
1068:
1009:
908:
864:Hyperthyroidism
795:bulimia nervosa
787:
775:
678:
676:
671:
668:
663:
658:
657:
646:
643:
638:
637:
626:
601:
585:
579:
540:
516:
508:
488:
468:
448:
428:
408:
388:
371:
363:
356:
338:
335:
330:
329:
302:
298:
289:
264:
260:
253:Protein binding
240:Bioavailability
232:Pharmacokinetic
226:
175:
138:
131:
111:
64:Meridia, others
49:
43:
17:
12:
11:
5:
9669:
9659:
9658:
9653:
9648:
9643:
9638:
9633:
9628:
9623:
9618:
9613:
9608:
9603:
9598:
9593:
9576:
9575:
9573:
9572:
9567:
9562:
9557:
9552:
9547:
9544:Levosalbutamol
9537:
9532:
9527:
9522:
9517:
9512:
9507:
9502:
9497:
9492:
9487:
9482:
9477:
9472:
9467:
9462:
9457:
9452:
9447:
9442:
9437:
9432:
9427:
9425:Desvenlafaxine
9422:
9417:
9412:
9407:
9402:
9396:
9394:
9390:
9389:
9387:
9386:
9381:
9376:
9368:
9360:
9355:
9350:
9340:
9338:Norepinephrine
9335:
9325:
9320:
9315:
9310:
9305:
9300:
9295:
9287:
9279:
9277:-Phenylalanine
9271:
9262:
9253:
9248:
9243:
9238:
9233:
9228:
9223:
9218:
9213:
9208:
9203:
9194:
9189:
9184:
9179:
9174:
9169:
9163:
9161:
9155:Catecholamines
9151:
9150:
9148:
9147:
9142:
9137:
9132:
9127:
9122:
9117:
9112:
9107:
9102:
9097:
9092:
9087:
9082:
9077:
9072:
9067:
9062:
9057:
9048:
9046:
9040:
9039:
9037:
9036:
9024:
9019:
9014:
9009:
9004:
8999:
8994:
8985:
8983:
8977:
8976:
8974:
8973:
8968:
8963:
8958:
8953:
8948:
8943:
8931:
8926:
8921:
8916:
8911:
8906:
8901:
8896:
8891:
8886:
8881:
8876:
8871:
8866:
8861:
8856:
8851:
8846:
8841:
8836:
8831:
8826:
8821:
8816:
8811:
8806:
8797:
8795:
8789:
8788:
8786:
8785:
8773:
8761:
8756:
8751:
8746:
8741:
8736:
8727:
8725:
8719:
8718:
8716:
8715:
8702:
8697:
8692:
8680:
8675:
8670:
8668:Methamnetamine
8665:
8660:
8655:
8650:
8645:
8640:
8635:
8630:
8625:
8620:
8615:
8610:
8605:
8600:
8595:
8590:
8585:
8580:
8575:
8570:
8565:
8560:
8555:
8550:
8545:
8540:
8528:
8523:
8518:
8513:
8508:
8503:
8498:
8493:
8488:
8483:
8478:
8473:
8468:
8463:
8458:
8453:
8448:
8443:
8438:
8433:
8428:
8423:
8415:
8410:
8405:
8400:
8395:
8385:
8380:
8375:
8370:
8365:
8360:
8355:
8350:
8345:
8340:
8335:
8330:
8325:
8320:
8306:
8301:
8296:
8291:
8289:Etilamfetamine
8286:
8281:
8276:
8271:
8266:
8261:
8256:
8251:
8237:
8232:
8227:
8222:
8217:
8212:
8207:
8202:
8190:
8185:
8180:
8175:
8170:
8165:
8160:
8155:
8150:
8145:
8140:
8135:
8130:
8125:
8120:
8115:
8110:
8105:
8100:
8095:
8090:
8085:
8080:
8075:
8070:
8065:
8060:
8051:
8049:
8043:
8042:
8040:
8039:
8034:
8022:
8017:
8008:
8007:
8002:
7994:
7986:
7978:
7970:
7965:
7959:
7954:
7952:Phenethylamine
7949:
7934:
7933:
7928:
7923:
7918:
7913:
7908:
7903:
7898:
7893:
7888:
7883:
7878:
7873:
7867:
7866:
7861:
7856:
7851:
7846:
7841:
7836:
7831:
7826:
7821:
7816:
7811:
7806:
7801:
7796:
7791:
7786:
7781:
7776:
7771:
7766:
7761:
7756:
7751:
7746:
7741:
7736:
7731:
7726:
7721:
7716:
7711:
7706:
7701:
7696:
7691:
7686:
7681:
7676:
7671:
7666:
7661:
7656:
7651:
7646:
7641:
7636:
7631:
7626:
7621:
7616:
7611:
7606:
7601:
7596:
7591:
7586:
7581:
7576:
7571:
7566:
7561:
7556:
7551:
7546:
7540:
7539:
7534:
7529:
7524:
7519:
7510:
7508:
7502:
7501:
7494:
7493:
7486:
7479:
7471:
7462:
7461:
7425:
7422:
7421:
7419:
7418:
7406:
7394:
7393:
7388:DAT enhancers:
7384:
7382:
7378:
7377:
7375:
7374:
7369:
7364:
7359:
7354:
7349:
7344:
7339:
7334:
7329:
7324:
7319:
7314:
7309:
7304:
7299:
7294:
7289:
7284:
7266:
7260:
7258:
7247:
7246:
7243:
7242:
7240:
7239:
7234:
7204:
7199:
7194:
7189:
7184:
7179:
7174:
7169:
7164:
7159:
7154:
7149:
7123:
7112:Antipsychotics
7109:
7106:tripelennamine
7090:dimenhydrinate
7086:chlorphenamine
7078:Antihistamines
7075:
7070:
7061:
7058:
7057:
7055:
7054:
7049:
7044:
7039:
7034:
7029:
7024:
7019:
7014:
7012:Cyanodothiepin
7009:
7004:
6999:
6990:
6987:
6986:
6984:
6983:
6973:
6968:
6963:
6958:
6953:
6948:
6943:
6938:
6933:
6928:
6923:
6918:
6913:
6908:
6903:
6898:
6893:
6888:
6883:
6878:
6873:
6868:
6863:
6858:
6853:
6848:
6843:
6838:
6833:
6828:
6823:
6818:
6813:
6808:
6803:
6798:
6789:
6786:
6785:
6783:
6782:
6777:
6772:
6767:
6762:
6757:
6752:
6747:
6742:
6737:
6735:Desvenlafaxine
6732:
6727:
6722:
6713:
6710:
6709:
6707:
6706:
6701:
6696:
6691:
6686:
6681:
6676:
6671:
6666:
6661:
6652:
6651:
6646:
6641:
6636:
6631:
6626:
6621:
6616:
6611:
6606:
6601:
6596:
6591:
6586:
6581:
6576:
6571:
6566:
6561:
6556:
6551:
6546:
6541:
6536:
6527:
6521:
6497:
6496:
6493:
6492:
6490:
6489:
6459:
6454:
6449:
6442:
6437:
6432:
6418:
6407:Antipsychotics
6404:
6401:tripelennamine
6393:chlorphenamine
6385:Antihistamines
6378:
6375:
6374:
6372:
6371:
6366:
6361:
6356:
6351:
6342:
6339:
6338:
6336:
6335:
6330:
6325:
6320:
6315:
6310:
6305:
6300:
6295:
6290:
6285:
6280:
6275:
6266:
6263:
6262:
6260:
6259:
6249:
6244:
6239:
6234:
6229:
6224:
6219:
6214:
6209:
6204:
6199:
6194:
6189:
6184:
6179:
6174:
6169:
6164:
6159:
6154:
6149:
6144:
6139:
6134:
6129:
6124:
6119:
6114:
6109:
6104:
6099:
6094:
6089:
6084:
6079:
6074:
6065:
6062:
6061:
6059:
6058:
6053:
6048:
6043:
6038:
6033:
6028:
6023:
6018:
6013:
6008:
6006:Desvenlafaxine
6003:
5998:
5989:
5986:
5985:
5983:
5982:
5977:
5972:
5967:
5962:
5957:
5952:
5947:
5942:
5937:
5932:
5927:
5922:
5917:
5912:
5903:
5900:
5899:
5897:
5896:
5891:
5886:
5881:
5876:
5871:
5866:
5861:
5856:
5851:
5846:
5841:
5836:
5831:
5826:
5817:
5811:
5787:
5786:
5783:
5782:
5780:
5779:
5774:
5772:Tripelennamine
5769:
5764:
5759:
5754:
5749:
5744:
5739:
5734:
5729:
5724:
5719:
5714:
5709:
5704:
5699:
5694:
5689:
5684:
5679:
5674:
5669:
5664:
5659:
5654:
5649:
5644:
5639:
5634:
5629:
5624:
5619:
5614:
5609:
5604:
5599:
5594:
5589:
5584:
5579:
5574:
5569:
5564:
5559:
5554:
5549:
5544:
5539:
5534:
5529:
5522:
5517:
5512:
5507:
5502:
5497:
5495:Amfonelic acid
5492:
5487:
5482:
5473:
5470:
5469:
5467:
5466:
5461:
5456:
5451:
5446:
5441:
5436:
5431:
5426:
5421:
5416:
5411:
5406:
5401:
5396:
5391:
5386:
5381:
5376:
5371:
5366:
5361:
5356:
5351:
5346:
5341:
5336:
5327:
5324:
5323:
5321:
5320:
5315:
5310:
5305:
5300:
5291:
5288:
5287:
5285:
5284:
5279:
5274:
5269:
5264:
5259:
5254:
5249:
5247:Ethylphenidate
5244:
5239:
5234:
5229:
5224:
5215:
5212:
5211:
5209:
5208:
5203:
5198:
5193:
5188:
5183:
5178:
5173:
5164:
5158:
5134:
5133:
5126:
5125:
5118:
5111:
5103:
5094:
5093:
5090:
5089:
5088:
5087:
5084:
5073:
5067:
5061:
5060:
5057:
5056:
5053:
5052:
5050:
5049:
5044:
5039:
5030:
5022:
5005:
4999:Ademetionine (
4995:
4992:
4991:
4981:
4980:
4977:
4976:
4974:
4973:
4969:
4961:
4951:
4937:
4932:
4901:
4898:
4897:
4885:
4884:
4881:
4880:
4877:
4876:
4874:
4873:
4864:
4862:
4853:
4847:
4846:
4844:
4843:
4838:
4833:
4828:
4823:
4818:
4813:
4804:
4802:
4793:
4787:
4786:
4784:
4783:
4774:
4773:
4764:
4763:
4758:
4753:
4748:
4743:
4738:
4733:
4728:
4723:
4718:
4713:
4708:
4703:
4698:
4693:
4688:
4679:
4677:
4669:
4668:
4656:
4655:
4652:
4651:
4648:
4647:
4645:
4644:
4638:
4636:
4632:
4631:
4629:
4628:
4623:
4618:
4613:
4607:
4605:
4594:
4593:
4591:
4590:
4585:
4580:
4575:
4570:
4565:
4560:
4555:
4550:
4545:
4540:
4535:
4530:
4525:
4520:
4518:Imipraminoxide
4515:
4510:
4505:
4500:
4495:
4490:
4485:
4480:
4475:
4470:
4465:
4460:
4455:
4449:
4447:
4432:
4431:
4415:
4414:
4411:
4410:
4407:
4406:
4404:
4403:
4398:
4393:
4388:
4383:
4378:
4373:
4368:
4363:
4358:
4353:
4348:
4343:
4338:
4333:
4328:
4322:
4320:
4316:
4315:
4313:
4312:
4307:
4301:
4299:
4288:
4287:
4285:
4284:
4279:
4274:
4268:
4266:
4255:
4254:
4252:
4251:
4246:
4241:
4235:
4233:
4222:
4221:
4219:
4218:
4213:
4208:
4202:
4200:
4189:
4188:
4186:
4185:
4180:
4175:
4169:
4167:
4156:
4155:
4153:
4152:
4147:
4142:
4137:
4132:
4127:
4125:Desvenlafaxine
4121:
4119:
4108:
4107:
4105:
4104:
4099:
4094:
4089:
4084:
4079:
4074:
4069:
4063:
4061:
4046:
4045:
4028:
4027:
4015:
4014:
4007:
4000:
3992:
3983:
3982:
3979:
3978:
3977:
3976:
3973:
3962:
3956:
3950:
3949:
3946:
3945:
3943:
3942:
3937:
3932:
3927:
3922:
3917:
3912:
3907:
3902:
3897:
3892:
3886:
3884:
3880:
3879:
3877:
3876:
3870:
3868:
3862:
3861:
3859:
3858:
3853:
3848:
3843:
3838:
3832:
3830:
3826:
3825:
3823:
3822:
3817:
3811:
3809:
3801:
3800:
3798:
3797:
3786:
3784:
3778:
3777:
3775:
3774:
3768:
3758:
3753:
3748:
3743:
3738:
3732:
3727:
3722:
3717:
3712:
3706:
3704:
3686:
3685:
3683:
3682:
3677:
3672:
3667:
3662:
3657:
3652:
3646:
3644:
3636:
3635:
3632:
3631:
3629:
3628:
3623:
3618:
3613:
3608:
3603:
3598:
3593:
3591:Phenethylamine
3588:
3583:
3578:
3573:
3568:
3558:
3553:
3548:
3543:
3538:
3528:
3523:
3518:
3512:
3510:
3506:
3505:
3503:
3502:
3492:
3487:
3482:
3477:
3472:
3467:
3462:
3456:
3454:
3448:
3447:
3445:
3444:
3439:
3434:
3424:
3419:
3414:
3409:
3404:
3399:
3394:
3389:
3384:
3379:
3374:
3369:
3367:Etilamfetamine
3364:
3359:
3354:
3349:
3344:
3339:
3334:
3329:
3324:
3319:
3314:
3309:
3304:
3299:
3294:
3289:
3284:
3278:
3276:
3262:
3256:
3255:
3239:
3238:
3231:
3224:
3216:
3210:
3209:
3204:
3192:
3178:
3177:External links
3175:
3173:
3172:
3142:
3117:
3106:on 3 July 2014
3087:
3058:
3028:
3010:
2988:
2959:
2933:
2904:
2881:
2832:
2806:
2792:
2761:
2758:on 2010-04-01.
2737:
2713:Pract Diab Int
2696:
2644:
2621:
2606:
2590:Public Citizen
2576:
2543:
2528:
2484:
2440:
2405:
2398:
2380:
2353:(5): 511–518.
2337:
2312:
2284:
2249:
2220:(3): 317–329.
2200:
2173:(2): 127–139.
2157:
2145:
2115:
2066:
2045:
2011:
1984:(5): 575–584.
1963:
1934:
1903:
1889:. 2010-01-22.
1874:
1843:
1817:
1796:
1775:
1754:
1740:2012-07-19 at
1724:
1699:
1680:
1651:
1629:(2023-03-31).
1617:
1615:
1612:
1580:In March 2010
1546:
1543:
1498:Public Citizen
1455:
1452:
1450:
1447:
1435:norsibutramine
1410:
1407:
1392:
1389:
1358:
1355:
1348:
1266:norepinephrine
1252:
1251:
1247:
1243:
1242:
1239:
1236:
1233:
1222:
1221:
1218:
1215:
1212:
1201:
1200:
1197:
1194:
1191:
1185:
1184:
1181:
1178:
1175:
1164:
1163:
1160:
1157:
1154:
1143:
1142:
1139:
1136:
1133:
1127:
1126:
1123:
1120:
1117:
1113:
1112:
1102:
1092:
1082:
1072:
1069:
1067:
1064:
1008:
1005:
942:blood pressure
907:
904:
903:
902:
895:
890:
879:
873:
867:
861:
854:
850:
847:
841:
835:
832:
825:antidepressant
817:
814:
808:
805:
786:
783:
774:
771:
734:European Union
685:
684:
673:
672:
670:
669:
666:
664:
661:
653:
652:
651:
648:
647:
645:
644:
641:
633:
632:
631:
628:
627:
625:
624:
616:
614:
606:
605:
599:
593:
592:
583:
577:
572:
566:
565:
561:
560:
550:
542:
541:
539:
538:
525:
523:
510:
509:
507:
506:
498:
496:
490:
489:
487:
486:
478:
476:
470:
469:
467:
466:
458:
456:
450:
449:
447:
446:
438:
436:
430:
429:
427:
426:
418:
416:
410:
409:
407:
406:
398:
396:
390:
389:
387:
386:
378:
376:
365:
364:
362:
361:
348:
346:
340:
339:
337:
336:
333:
325:
324:
323:
320:
319:
315:
314:
311:
305:
304:
300:
296:
293:
284:
283:
273:
267:
266:
262:
258:
255:
249:
248:
242:
236:
235:
228:
227:
225:
224:
212:
204:
190:
188:
182:
181:
177:
176:
174:
173:
160:
158:
152:
151:
141:
139:administration
133:
132:
130:
129:
126:
116:
114:
106:
105:
98:
92:
91:
84:
74:
73:
70:
66:
65:
62:
56:
55:
51:
50:
41:
33:
32:
15:
9:
6:
4:
3:
2:
9668:
9657:
9654:
9652:
9649:
9647:
9644:
9642:
9639:
9637:
9634:
9632:
9629:
9627:
9624:
9622:
9619:
9617:
9614:
9612:
9609:
9607:
9604:
9602:
9599:
9597:
9594:
9592:
9589:
9588:
9586:
9571:
9568:
9566:
9563:
9561:
9560:Thiamphenicol
9558:
9556:
9555:Theodrenaline
9553:
9551:
9548:
9545:
9541:
9538:
9536:
9533:
9531:
9528:
9526:
9523:
9521:
9518:
9516:
9513:
9511:
9508:
9506:
9503:
9501:
9498:
9496:
9493:
9491:
9488:
9486:
9483:
9481:
9478:
9476:
9473:
9471:
9470:Fluorolintane
9468:
9466:
9463:
9461:
9458:
9456:
9453:
9451:
9448:
9446:
9443:
9441:
9438:
9436:
9433:
9431:
9428:
9426:
9423:
9421:
9418:
9416:
9413:
9411:
9408:
9406:
9403:
9401:
9398:
9397:
9395:
9393:Miscellaneous
9391:
9385:
9382:
9380:
9379:Phenylephrine
9377:
9375:
9373:
9369:
9367:
9365:
9361:
9359:
9358:Orciprenaline
9356:
9354:
9351:
9348:
9344:
9341:
9339:
9336:
9333:
9332:Levonordefrin
9329:
9326:
9324:
9321:
9319:
9316:
9314:
9311:
9309:
9306:
9304:
9301:
9299:
9296:
9294:
9292:
9288:
9286:
9280:
9278:
9272:
9269:
9263:
9260:
9254:
9252:
9249:
9247:
9244:
9242:
9239:
9237:
9234:
9232:
9229:
9227:
9224:
9222:
9219:
9217:
9214:
9212:
9209:
9207:
9204:
9201:
9195:
9193:
9190:
9188:
9185:
9183:
9180:
9178:
9175:
9173:
9170:
9168:
9165:
9164:
9162:
9156:
9152:
9146:
9143:
9141:
9138:
9136:
9133:
9131:
9128:
9126:
9123:
9121:
9118:
9116:
9113:
9111:
9108:
9106:
9103:
9101:
9098:
9096:
9093:
9091:
9088:
9086:
9083:
9081:
9078:
9076:
9073:
9071:
9068:
9066:
9063:
9061:
9058:
9056:
9053:
9050:
9049:
9047:
9045:
9041:
9035:
9032:
9028:
9025:
9023:
9020:
9018:
9015:
9013:
9010:
9008:
9005:
9003:
9000:
8998:
8995:
8993:
8990:
8987:
8986:
8984:
8982:
8978:
8972:
8969:
8967:
8964:
8962:
8959:
8957:
8954:
8952:
8949:
8947:
8944:
8942:
8939:
8935:
8932:
8930:
8927:
8925:
8922:
8920:
8917:
8915:
8912:
8910:
8907:
8905:
8902:
8900:
8899:Methcathinone
8897:
8895:
8892:
8890:
8887:
8885:
8882:
8880:
8877:
8875:
8872:
8870:
8867:
8865:
8862:
8860:
8857:
8855:
8852:
8850:
8847:
8845:
8842:
8840:
8837:
8835:
8832:
8830:
8827:
8825:
8822:
8820:
8817:
8815:
8812:
8810:
8807:
8805:
8802:
8799:
8798:
8796:
8794:
8790:
8784:
8781:
8777:
8774:
8772:
8769:
8765:
8762:
8760:
8757:
8755:
8754:Mephentermine
8752:
8750:
8747:
8745:
8742:
8740:
8737:
8735:
8732:
8729:
8728:
8726:
8724:
8720:
8713:
8706:
8703:
8701:
8698:
8696:
8693:
8691:
8688:
8684:
8681:
8679:
8676:
8674:
8671:
8669:
8666:
8664:
8661:
8659:
8656:
8654:
8651:
8649:
8646:
8644:
8641:
8639:
8636:
8634:
8631:
8629:
8626:
8624:
8621:
8619:
8616:
8614:
8611:
8609:
8606:
8604:
8603:6-Chloro-MDMA
8601:
8599:
8596:
8594:
8591:
8589:
8586:
8584:
8581:
8579:
8576:
8574:
8571:
8569:
8566:
8564:
8561:
8559:
8556:
8554:
8551:
8549:
8546:
8544:
8541:
8539:
8536:
8532:
8529:
8527:
8526:Xylopropamine
8524:
8522:
8519:
8517:
8514:
8512:
8509:
8507:
8504:
8502:
8499:
8497:
8494:
8492:
8489:
8487:
8484:
8482:
8479:
8477:
8474:
8472:
8469:
8467:
8464:
8462:
8459:
8457:
8454:
8452:
8449:
8447:
8444:
8442:
8439:
8437:
8434:
8432:
8429:
8427:
8424:
8422:
8416:
8414:
8411:
8409:
8406:
8404:
8401:
8399:
8396:
8393:
8389:
8386:
8384:
8381:
8379:
8376:
8374:
8371:
8369:
8366:
8364:
8361:
8359:
8356:
8354:
8351:
8349:
8346:
8344:
8341:
8339:
8336:
8334:
8331:
8329:
8326:
8324:
8321:
8318:
8314:
8310:
8307:
8305:
8302:
8300:
8297:
8295:
8292:
8290:
8287:
8285:
8282:
8280:
8277:
8275:
8272:
8270:
8267:
8265:
8264:Benzphetamine
8262:
8260:
8257:
8255:
8252:
8249:
8245:
8241:
8238:
8236:
8233:
8231:
8228:
8226:
8223:
8221:
8218:
8216:
8213:
8211:
8208:
8206:
8203:
8201:
8198:
8194:
8191:
8189:
8186:
8184:
8181:
8179:
8176:
8174:
8171:
8169:
8166:
8164:
8161:
8159:
8156:
8154:
8151:
8149:
8146:
8144:
8141:
8139:
8136:
8134:
8131:
8129:
8126:
8124:
8121:
8119:
8116:
8114:
8111:
8109:
8106:
8104:
8101:
8099:
8096:
8094:
8091:
8089:
8086:
8084:
8081:
8079:
8076:
8074:
8071:
8069:
8066:
8064:
8061:
8059:
8056:
8055:Psychedelics:
8053:
8052:
8050:
8048:
8044:
8038:
8035:
8033:
8030:
8026:
8023:
8021:
8018:
8016:
8013:
8010:
8009:
8006:
8003:
8001:
7999:
7995:
7993:
7991:
7987:
7985:
7983:
7979:
7977:
7975:
7971:
7969:
7966:
7964:(amphetamine)
7963:
7960:
7958:
7955:
7953:
7950:
7948:
7945:
7944:
7943:
7942:
7939:
7932:
7929:
7927:
7924:
7922:
7919:
7917:
7914:
7912:
7909:
7907:
7904:
7902:
7899:
7897:
7894:
7892:
7889:
7887:
7886:Isoproscaline
7884:
7882:
7879:
7877:
7874:
7872:
7871:Allylescaline
7869:
7868:
7865:
7862:
7860:
7857:
7855:
7852:
7850:
7847:
7845:
7842:
7840:
7837:
7835:
7832:
7830:
7827:
7825:
7822:
7820:
7817:
7815:
7812:
7810:
7807:
7805:
7802:
7800:
7797:
7795:
7792:
7790:
7787:
7785:
7782:
7780:
7777:
7775:
7772:
7770:
7767:
7765:
7762:
7760:
7757:
7755:
7752:
7750:
7747:
7745:
7742:
7740:
7737:
7735:
7732:
7730:
7727:
7725:
7722:
7720:
7717:
7715:
7712:
7710:
7707:
7705:
7702:
7700:
7697:
7695:
7692:
7690:
7687:
7685:
7682:
7680:
7677:
7675:
7672:
7670:
7667:
7665:
7662:
7660:
7657:
7655:
7652:
7650:
7647:
7645:
7642:
7640:
7637:
7635:
7632:
7630:
7627:
7625:
7622:
7620:
7617:
7615:
7612:
7610:
7607:
7605:
7602:
7600:
7597:
7595:
7592:
7590:
7587:
7585:
7582:
7580:
7577:
7575:
7572:
7570:
7567:
7565:
7562:
7560:
7557:
7555:
7552:
7550:
7547:
7545:
7542:
7541:
7538:
7535:
7533:
7530:
7528:
7525:
7523:
7520:
7518:
7515:
7514:Psychedelics:
7512:
7511:
7509:
7507:
7503:
7499:
7492:
7487:
7485:
7480:
7478:
7473:
7472:
7469:
7458:
7457:
7453:
7449:
7448:Serotonergics
7445:
7444:Dopaminergics
7441:
7437:
7433:
7430:
7423:
7417:
7414:
7410:
7407:
7405:
7402:
7401:Agonist-like:
7399:
7396:
7395:
7392:
7389:
7386:
7385:
7383:
7379:
7373:
7370:
7368:
7365:
7363:
7362:Tetrabenazine
7360:
7358:
7355:
7353:
7350:
7348:
7345:
7343:
7340:
7338:
7335:
7333:
7330:
7328:
7325:
7323:
7320:
7318:
7315:
7313:
7310:
7308:
7305:
7303:
7300:
7298:
7295:
7293:
7290:
7288:
7285:
7282:
7278:
7274:
7270:
7267:
7265:
7262:
7261:
7259:
7254:
7248:
7238:
7235:
7232:
7228:
7224:
7220:
7216:
7212:
7208:
7205:
7203:
7200:
7198:
7195:
7193:
7190:
7188:
7185:
7183:
7180:
7178:
7175:
7173:
7170:
7168:
7165:
7163:
7160:
7158:
7155:
7153:
7150:
7147:
7146:phencyclidine
7143:
7142:methoxetamine
7139:
7135:
7131:
7127:
7124:
7121:
7117:
7113:
7110:
7107:
7103:
7099:
7095:
7091:
7087:
7083:
7079:
7076:
7074:
7071:
7069:
7066:
7063:
7062:
7059:
7053:
7052:Protriptyline
7050:
7048:
7045:
7043:
7042:Nortriptyline
7040:
7038:
7035:
7033:
7030:
7028:
7025:
7023:
7020:
7018:
7015:
7013:
7010:
7008:
7005:
7003:
7000:
6998:
6997:Amitriptyline
6995:
6992:
6991:
6988:
6981:
6977:
6974:
6972:
6969:
6967:
6964:
6962:
6961:Tedatioxetine
6959:
6957:
6954:
6952:
6949:
6947:
6944:
6942:
6939:
6937:
6934:
6932:
6929:
6927:
6924:
6922:
6919:
6917:
6914:
6912:
6909:
6907:
6904:
6902:
6899:
6897:
6894:
6892:
6889:
6887:
6884:
6882:
6879:
6877:
6874:
6872:
6869:
6867:
6864:
6862:
6859:
6857:
6854:
6852:
6849:
6847:
6844:
6842:
6839:
6837:
6834:
6832:
6829:
6827:
6824:
6822:
6821:Centanafadine
6819:
6817:
6814:
6812:
6809:
6807:
6804:
6802:
6799:
6797:
6794:
6791:
6790:
6787:
6781:
6778:
6776:
6773:
6771:
6768:
6766:
6765:N-Methyl-PPPA
6763:
6761:
6758:
6756:
6753:
6751:
6748:
6746:
6743:
6741:
6738:
6736:
6733:
6731:
6728:
6726:
6723:
6721:
6718:
6715:
6714:
6711:
6705:
6702:
6700:
6697:
6695:
6692:
6690:
6687:
6685:
6682:
6680:
6677:
6675:
6672:
6670:
6667:
6665:
6662:
6660:
6657:
6654:
6653:
6650:
6647:
6645:
6642:
6640:
6637:
6635:
6632:
6630:
6627:
6625:
6622:
6620:
6617:
6615:
6612:
6610:
6607:
6605:
6604:Norfluoxetine
6602:
6600:
6597:
6595:
6592:
6590:
6587:
6585:
6582:
6580:
6577:
6575:
6572:
6570:
6567:
6565:
6562:
6560:
6557:
6555:
6552:
6550:
6547:
6545:
6544:Centpropazine
6542:
6540:
6537:
6535:
6532:
6529:
6528:
6525:
6522:
6515:
6504:
6498:
6487:
6483:
6479:
6475:
6471:
6467:
6466:desmetramadol
6463:
6460:
6458:
6455:
6453:
6450:
6448:
6447:
6446:Ginkgo biloba
6443:
6441:
6438:
6436:
6433:
6430:
6429:phencyclidine
6426:
6422:
6419:
6416:
6412:
6408:
6405:
6402:
6398:
6394:
6390:
6386:
6383:
6380:
6379:
6376:
6370:
6367:
6365:
6362:
6360:
6357:
6355:
6352:
6350:
6347:
6344:
6343:
6340:
6334:
6331:
6329:
6328:Protriptyline
6326:
6324:
6323:Nortriptyline
6321:
6319:
6316:
6314:
6311:
6309:
6306:
6304:
6301:
6299:
6296:
6294:
6291:
6289:
6286:
6284:
6281:
6279:
6276:
6274:
6273:Amitriptyline
6271:
6268:
6267:
6264:
6257:
6253:
6250:
6248:
6245:
6243:
6240:
6238:
6237:Tedatioxetine
6235:
6233:
6230:
6228:
6225:
6223:
6220:
6218:
6215:
6213:
6210:
6208:
6205:
6203:
6200:
6198:
6195:
6193:
6190:
6188:
6185:
6183:
6180:
6178:
6175:
6173:
6170:
6168:
6165:
6163:
6160:
6158:
6155:
6153:
6150:
6148:
6145:
6143:
6140:
6138:
6135:
6133:
6130:
6128:
6125:
6123:
6120:
6118:
6115:
6113:
6110:
6108:
6105:
6103:
6100:
6098:
6097:Centanafadine
6095:
6093:
6090:
6088:
6085:
6083:
6080:
6078:
6075:
6073:
6070:
6067:
6066:
6063:
6057:
6054:
6052:
6049:
6047:
6044:
6042:
6039:
6037:
6036:N-Methyl-PPPA
6034:
6032:
6029:
6027:
6024:
6022:
6019:
6017:
6014:
6012:
6009:
6007:
6004:
6002:
5999:
5997:
5994:
5991:
5990:
5987:
5981:
5978:
5976:
5973:
5971:
5968:
5966:
5963:
5961:
5958:
5956:
5953:
5951:
5948:
5946:
5943:
5941:
5938:
5936:
5933:
5931:
5928:
5926:
5923:
5921:
5918:
5916:
5913:
5911:
5908:
5905:
5904:
5901:
5895:
5892:
5890:
5887:
5885:
5882:
5880:
5877:
5875:
5872:
5870:
5867:
5865:
5862:
5860:
5857:
5855:
5852:
5850:
5847:
5845:
5842:
5840:
5837:
5835:
5832:
5830:
5827:
5825:
5822:
5819:
5818:
5815:
5812:
5805:
5794:
5788:
5778:
5775:
5773:
5770:
5768:
5765:
5763:
5762:Tedatioxetine
5760:
5758:
5755:
5753:
5750:
5748:
5745:
5743:
5740:
5738:
5735:
5733:
5730:
5728:
5725:
5723:
5720:
5718:
5715:
5713:
5710:
5708:
5705:
5703:
5700:
5698:
5695:
5693:
5690:
5688:
5685:
5683:
5680:
5678:
5675:
5673:
5670:
5668:
5665:
5663:
5660:
5658:
5655:
5653:
5650:
5648:
5645:
5643:
5640:
5638:
5635:
5633:
5630:
5628:
5625:
5623:
5620:
5618:
5615:
5613:
5610:
5608:
5605:
5603:
5600:
5598:
5595:
5593:
5590:
5588:
5585:
5583:
5580:
5578:
5575:
5573:
5570:
5568:
5565:
5563:
5560:
5558:
5555:
5553:
5550:
5548:
5545:
5543:
5540:
5538:
5535:
5533:
5530:
5528:
5527:
5523:
5521:
5518:
5516:
5513:
5511:
5508:
5506:
5503:
5501:
5498:
5496:
5493:
5491:
5488:
5486:
5483:
5481:
5478:
5475:
5474:
5471:
5465:
5462:
5460:
5457:
5455:
5452:
5450:
5447:
5445:
5442:
5440:
5437:
5435:
5432:
5430:
5427:
5425:
5422:
5420:
5417:
5415:
5412:
5410:
5407:
5405:
5402:
5400:
5397:
5395:
5392:
5390:
5387:
5385:
5384:Ioflupane (I)
5382:
5380:
5377:
5375:
5372:
5370:
5367:
5365:
5362:
5360:
5357:
5355:
5352:
5350:
5347:
5345:
5342:
5340:
5337:
5335:
5332:
5329:
5328:
5325:
5319:
5316:
5314:
5311:
5309:
5306:
5304:
5301:
5299:
5296:
5295:Pyrrolidines:
5293:
5292:
5289:
5283:
5282:Tenocyclidine
5280:
5278:
5275:
5273:
5270:
5268:
5267:Phencyclidine
5265:
5263:
5260:
5258:
5255:
5253:
5250:
5248:
5245:
5243:
5240:
5238:
5235:
5233:
5230:
5228:
5225:
5223:
5220:
5217:
5216:
5213:
5207:
5204:
5202:
5199:
5197:
5194:
5192:
5189:
5187:
5184:
5182:
5179:
5177:
5174:
5172:
5169:
5166:
5165:
5162:
5159:
5152:
5141:
5135:
5131:
5124:
5119:
5117:
5112:
5110:
5105:
5104:
5101:
5085:
5083:
5080:
5079:
5077:
5074:
5071:
5068:
5066:
5063:
5062:
5058:
5048:
5045:
5043:
5040:
5038:
5031:
5029:
5027:
5023:
5020:
5016:
5012:
5011:neurosteroids
5009:
5006:
5004:
4997:
4996:
4993:
4989:Miscellaneous
4986:
4982:
4967:
4966:levothyroxine
4959:
4955:
4952:
4949:
4945:
4941:
4938:
4936:
4933:
4930:
4926:
4922:
4918:
4914:
4913:brexpiprazole
4910:
4906:
4903:
4902:
4899:
4895:
4890:
4886:
4872:
4869:
4868:Irreversible:
4866:
4865:
4863:
4857:
4848:
4842:
4839:
4837:
4834:
4832:
4829:
4827:
4824:
4822:
4819:
4817:
4814:
4812:
4809:
4806:
4805:
4803:
4797:
4788:
4782:
4779:
4776:
4775:
4772:
4769:
4766:
4765:
4762:
4759:
4757:
4754:
4752:
4749:
4747:
4744:
4742:
4739:
4737:
4734:
4732:
4729:
4727:
4724:
4722:
4719:
4717:
4714:
4712:
4709:
4707:
4704:
4702:
4701:Isocarboxazid
4699:
4697:
4694:
4692:
4689:
4687:
4684:
4683:Irreversible:
4681:
4680:
4678:
4676:Non-selective
4674:
4670:
4666:
4661:
4657:
4643:
4640:
4639:
4637:
4633:
4627:
4624:
4622:
4619:
4617:
4614:
4612:
4609:
4608:
4606:
4601:
4595:
4589:
4586:
4584:
4581:
4579:
4576:
4574:
4573:Protriptyline
4571:
4569:
4566:
4564:
4561:
4559:
4556:
4554:
4551:
4549:
4548:Nortriptyline
4546:
4544:
4543:Nitroxazepine
4541:
4539:
4536:
4534:
4531:
4529:
4526:
4524:
4521:
4519:
4516:
4514:
4511:
4509:
4506:
4504:
4501:
4499:
4496:
4494:
4491:
4489:
4486:
4484:
4483:Demexiptiline
4481:
4479:
4476:
4474:
4471:
4469:
4466:
4464:
4461:
4459:
4458:Amitriptyline
4456:
4454:
4451:
4450:
4448:
4443:
4437:
4433:
4429:
4425:
4420:
4416:
4402:
4399:
4397:
4394:
4392:
4389:
4387:
4384:
4382:
4379:
4377:
4374:
4372:
4369:
4367:
4364:
4362:
4359:
4357:
4354:
4352:
4349:
4347:
4344:
4342:
4339:
4337:
4334:
4332:
4329:
4327:
4324:
4323:
4321:
4317:
4311:
4308:
4306:
4303:
4302:
4300:
4295:
4289:
4283:
4280:
4278:
4275:
4273:
4270:
4269:
4267:
4262:
4256:
4250:
4247:
4245:
4242:
4240:
4237:
4236:
4234:
4229:
4223:
4217:
4214:
4212:
4209:
4207:
4204:
4203:
4201:
4196:
4190:
4184:
4181:
4179:
4176:
4174:
4171:
4170:
4168:
4163:
4157:
4151:
4148:
4146:
4143:
4141:
4138:
4136:
4133:
4131:
4128:
4126:
4123:
4122:
4120:
4115:
4109:
4103:
4100:
4098:
4095:
4093:
4090:
4088:
4085:
4083:
4080:
4078:
4075:
4073:
4070:
4068:
4065:
4064:
4062:
4057:
4051:
4047:
4043:
4039:
4033:
4029:
4024:
4020:
4013:
4008:
4006:
4001:
3999:
3994:
3993:
3990:
3974:
3972:
3969:
3968:
3966:
3963:
3960:
3957:
3955:
3952:
3951:
3947:
3941:
3938:
3936:
3933:
3931:
3928:
3926:
3923:
3921:
3920:Setmelanotide
3918:
3916:
3913:
3911:
3908:
3906:
3903:
3901:
3898:
3896:
3893:
3891:
3888:
3887:
3885:
3881:
3875:
3872:
3871:
3869:
3867:
3863:
3857:
3854:
3852:
3849:
3847:
3844:
3842:
3839:
3837:
3834:
3833:
3831:
3827:
3821:
3818:
3816:
3813:
3812:
3810:
3808:
3802:
3795:
3791:
3788:
3787:
3785:
3783:
3779:
3772:
3769:
3766:
3765:+cagrilintide
3762:
3759:
3757:
3754:
3752:
3751:Oxyntomodulin
3749:
3747:
3744:
3742:
3739:
3736:
3733:
3731:
3728:
3726:
3723:
3721:
3718:
3716:
3713:
3711:
3708:
3707:
3705:
3703:
3699:
3695:
3691:
3687:
3681:
3678:
3676:
3673:
3671:
3668:
3666:
3663:
3661:
3658:
3656:
3653:
3651:
3648:
3647:
3645:
3643:
3637:
3627:
3624:
3622:
3619:
3617:
3614:
3612:
3609:
3607:
3604:
3602:
3599:
3597:
3596:Phenmetrazine
3594:
3592:
3589:
3587:
3584:
3582:
3579:
3577:
3574:
3572:
3569:
3566:
3562:
3559:
3557:
3554:
3552:
3549:
3547:
3544:
3542:
3539:
3536:
3532:
3529:
3527:
3524:
3522:
3519:
3517:
3514:
3513:
3511:
3507:
3500:
3496:
3493:
3491:
3488:
3486:
3483:
3481:
3478:
3476:
3473:
3471:
3468:
3466:
3463:
3461:
3458:
3457:
3455:
3453:
3449:
3443:
3440:
3438:
3437:Xylopropamine
3435:
3432:
3428:
3425:
3423:
3420:
3418:
3415:
3413:
3410:
3408:
3405:
3403:
3400:
3398:
3395:
3393:
3390:
3388:
3385:
3383:
3380:
3378:
3375:
3373:
3370:
3368:
3365:
3363:
3360:
3358:
3355:
3353:
3350:
3348:
3345:
3343:
3340:
3338:
3335:
3333:
3330:
3328:
3325:
3323:
3320:
3318:
3315:
3313:
3312:Benzphetamine
3310:
3308:
3305:
3303:
3300:
3298:
3295:
3293:
3290:
3288:
3285:
3283:
3280:
3279:
3277:
3275:
3270:
3266:
3263:
3261:
3257:
3252:
3248:
3244:
3237:
3232:
3230:
3225:
3223:
3218:
3217:
3214:
3208:
3205:
3202:
3201:
3196:
3193:
3191:
3187:
3184:
3181:
3180:
3161:
3157:
3153:
3146:
3138:
3134:
3133:
3128:
3121:
3105:
3101:
3097:
3091:
3076:
3072:
3068:
3062:
3047:
3043:
3039:
3032:
3024:
3020:
3014:
3006:
3002:
2998:
2992:
2977:
2973:
2969:
2963:
2947:
2943:
2937:
2922:
2918:
2914:
2908:
2901:
2897:
2893:
2890:
2885:
2877:
2873:
2868:
2863:
2859:
2855:
2851:
2847:
2843:
2836:
2820:
2816:
2810:
2802:
2796:
2780:
2776:
2772:
2765:
2754:
2747:
2741:
2730:
2726:
2722:
2718:
2714:
2707:
2700:
2692:
2688:
2683:
2678:
2674:
2670:
2666:
2662:
2655:
2648:
2640:
2636:
2632:
2625:
2617:
2610:
2595:
2591:
2587:
2580:
2565:
2561:
2557:
2550:
2548:
2539:
2532:
2524:
2520:
2516:
2512:
2508:
2504:
2500:
2496:
2488:
2480:
2476:
2472:
2468:
2464:
2460:
2456:
2452:
2444:
2436:
2432:
2428:
2424:
2421:(1): 93–102.
2420:
2416:
2409:
2401:
2395:
2391:
2384:
2376:
2372:
2368:
2364:
2360:
2356:
2352:
2348:
2341:
2326:
2322:
2316:
2308:
2304:
2300:
2296:
2288:
2269:
2262:
2256:
2254:
2245:
2241:
2236:
2231:
2227:
2223:
2219:
2215:
2211:
2204:
2196:
2192:
2188:
2184:
2180:
2176:
2172:
2168:
2161:
2149:
2135:on 2008-08-09
2134:
2130:
2124:
2122:
2120:
2111:
2107:
2102:
2097:
2093:
2089:
2085:
2081:
2077:
2070:
2062:
2058:
2052:
2050:
2034:
2030:
2026:
2020:
2018:
2016:
2007:
2003:
1999:
1995:
1991:
1987:
1983:
1979:
1972:
1970:
1968:
1952:
1948:
1944:
1938:
1922:
1918:
1914:
1907:
1892:
1888:
1884:
1878:
1864:on 2011-05-11
1860:
1853:
1847:
1831:
1827:
1821:
1806:
1800:
1785:
1779:
1764:
1758:
1751:
1750:Press Release
1747:
1743:
1742:archive.today
1739:
1736:
1728:
1714:on 2011-10-07
1713:
1709:
1703:
1696:
1692:
1689:
1684:
1670:on 2014-07-03
1669:
1665:
1661:
1655:
1640:
1636:
1632:
1628:
1622:
1618:
1611:
1608:
1605:
1603:
1597:
1593:
1591:
1586:
1583:
1582:Health Canada
1578:
1576:
1572:
1566:
1564:
1560:
1556:
1552:
1542:
1539:
1534:
1531:
1529:
1524:
1522:
1518:
1513:
1509:
1507:
1503:
1499:
1496:-founded NGO
1495:
1491:
1490:renal failure
1486:
1484:
1478:
1476:
1473:
1469:
1465:
1461:
1446:
1444:
1440:
1436:
1432:
1428:
1424:
1420:
1416:
1406:
1404:
1401:
1398:
1397:hydrochloride
1388:
1386:
1382:
1379:
1376:
1372:
1368:
1364:
1354:
1352:
1344:
1340:
1335:
1333:
1329:
1325:
1321:
1317:
1313:
1308:
1306:
1302:
1297:
1295:
1291:
1287:
1283:
1279:
1275:
1271:
1267:
1263:
1259:
1244:
1240:
1237:
1234:
1232:
1230:
1224:
1223:
1219:
1216:
1213:
1211:
1209:
1203:
1202:
1198:
1195:
1192:
1190:
1187:
1186:
1182:
1179:
1176:
1174:
1172:
1166:
1165:
1161:
1158:
1155:
1153:
1151:
1145:
1144:
1140:
1137:
1134:
1132:
1129:
1128:
1124:
1121:
1118:
1115:
1114:
1108:
1103:
1098:
1093:
1088:
1083:
1080:
1079:
1063:
1061:
1057:
1053:
1049:
1044:
1042:
1038:
1034:
1030:
1026:
1022:
1018:
1014:
1004:
1001:
996:
994:
990:
986:
982:
978:
974:
970:
966:
962:
957:
955:
951:
946:
943:
938:
936:
932:
928:
923:
921:
917:
916:heart attacks
913:
900:
897:Pregnant and
896:
894:
891:
888:
884:
880:
877:
874:
872:
869:Closed angle
868:
865:
862:
859:
855:
851:
848:
846:
842:
839:
836:
833:
830:
826:
822:
821:MAO inhibitor
818:
815:
812:
809:
806:
804:
800:
796:
792:
791:
790:
782:
780:
770:
767:
765:
762:
758:
754:
750:
745:
743:
739:
735:
731:
727:
723:
719:
715:
711:
707:
704:similar to a
703:
699:
695:
691:
681:
674:
665:
660:
659:
656:
649:
640:
639:
636:
629:
622:
618:
617:
615:
612:
607:
600:
598:
594:
573:
571:
567:
562:
558:
554:
551:
549:
547:ECHA InfoCard
543:
535:
531:
530:DTXSID1023578
527:
526:
524:
515:
511:
504:
500:
499:
497:
495:
491:
484:
480:
479:
477:
475:
471:
464:
460:
459:
457:
455:
451:
444:
440:
439:
437:
435:
431:
424:
420:
419:
417:
415:
411:
404:
400:
399:
397:
395:
391:
384:
380:
379:
377:
370:
366:
359:
354:
350:
349:
347:
345:
341:
332:
331:
328:
321:
316:
312:
310:
306:
294:
292:
285:
281:
277:
274:
272:
268:
256:
254:
250:
247:
243:
241:
237:
233:
229:
223:
213:
205:
202:
192:
191:
189:
187:
183:
178:
170:
165:
162:
161:
159:
157:
153:
149:
145:
142:
140:
134:
127:
118:
117:
115:
113:
107:
103:
99:
97:
93:
89:
85:
83:
79:
75:
71:
67:
63:
61:
57:
54:Clinical data
52:
47:
39:
34:
30:
25:
9601:Cyclobutanes
9550:Solriamfetol
9465:Famprofazone
9371:
9363:
9349:-Octopamine)
9346:
9343:Norfenefrine
9298:Metanephrine
9290:
9246:Isoprenaline
9202:(Dextrodopa)
9187:Adrenochrome
9145:Pyrovalerone
9051:
9030:
8989:Entactogens:
8988:
8938:Entactogens:
8937:
8884:Ethcathinone
8800:
8779:
8768:Entactogens:
8767:
8730:
8723:Phentermines
8686:
8535:Entactogens:
8534:
8531:Zylofuramine
8510:
8309:Fenfluramine
8304:Fenethylline
8254:Amphetaminil
8235:Amfepentorex
8196:
8054:
8047:Amphetamines
8028:
8012:Entactogens:
8011:
7997:
7989:
7981:
7973:
7937:
7935:
7911:Metaescaline
7513:
7428:
7427:
7412:
7400:
7397:
7387:
7297:Bietaserpine
7269:Amphetamines
7192:Mifepristone
7182:Medifoxamine
7064:
7007:Clomipramine
7002:Cianopramine
6993:
6955:
6846:Diclofensine
6816:Brasofensine
6792:
6716:
6704:Vortioxetine
6655:
6574:Escitalopram
6530:
6452:Indeloxazine
6444:
6381:
6364:Oxaprotiline
6345:
6333:Trimipramine
6288:Clomipramine
6283:Cianopramine
6278:Butriptyline
6269:
6231:
6122:Diclofensine
6092:Brasofensine
6068:
5992:
5980:Solriamfetol
5906:
5889:Teniloxazine
5849:Esreboxetine
5820:
5752:Solriamfetol
5746:
5672:Medifoxamine
5562:Dimethocaine
5552:Diclofensine
5524:
5476:
5364:Difluoropine
5359:Dichloropane
5344:Brasofensine
5330:
5318:Pyrovalerone
5294:
5219:Piperidines:
5218:
5168:Piperazines:
5167:
5033:Oxitriptan (
5025:
4909:aripiprazole
4867:
4816:Metralindole
4807:
4777:
4767:
4746:Pivhydrazine
4736:Pheniprazine
4682:
4588:Trimipramine
4578:Quinupramine
4478:Clomipramine
4473:Butriptyline
4396:Teniloxazine
4391:Tandospirone
4376:Metryptamine
4371:Medifoxamine
4356:Indeloxazine
4310:Vortioxetine
4072:Escitalopram
3794:+semaglutide
3790:Cagrilintide
3746:Orforglipron
3620:
3616:Pyrovalerone
3565:+phentermine
3561:Fenfluramine
3556:Fenbutrazate
3442:Zylofuramine
3377:Fenethylline
3307:Amphetaminil
3292:Amfepentorex
3269:Amphetamines
3200:Merck Manual
3198:
3164:. Retrieved
3155:
3145:
3137:the original
3130:
3120:
3108:. Retrieved
3104:the original
3099:
3090:
3079:. Retrieved
3070:
3061:
3050:. Retrieved
3041:
3031:
3023:the original
3013:
3005:the original
3000:
2991:
2980:. Retrieved
2971:
2962:
2950:. Retrieved
2936:
2925:. Retrieved
2907:
2884:
2849:
2845:
2835:
2823:. Retrieved
2809:
2795:
2785:February 25,
2783:. Retrieved
2774:
2764:
2753:the original
2740:
2729:the original
2719:(3): 96–97.
2716:
2712:
2699:
2664:
2660:
2647:
2634:
2624:
2609:
2598:. Retrieved
2579:
2568:. Retrieved
2559:
2537:
2531:
2498:
2494:
2487:
2454:
2450:
2443:
2418:
2414:
2408:
2389:
2383:
2350:
2346:
2340:
2329:. Retrieved
2315:
2298:
2294:
2287:
2275:. Retrieved
2217:
2213:
2203:
2170:
2166:
2160:
2148:
2137:. Retrieved
2133:the original
2083:
2079:
2069:
2061:the original
2037:. Retrieved
2028:
1981:
1977:
1955:. Retrieved
1946:
1937:
1925:. Retrieved
1921:the original
1916:
1906:
1895:. Retrieved
1886:
1877:
1866:. Retrieved
1859:the original
1846:
1836:February 20,
1834:. Retrieved
1820:
1809:. Retrieved
1799:
1788:. Retrieved
1778:
1767:. Retrieved
1757:
1748:in Germany.
1727:
1716:. Retrieved
1712:the original
1702:
1683:
1672:. Retrieved
1668:the original
1663:
1654:
1643:. Retrieved
1621:
1609:
1606:
1598:
1594:
1587:
1579:
1567:
1558:
1548:
1535:
1532:
1525:
1517:David Haslam
1514:
1510:
1502:David Graham
1487:
1479:
1457:
1442:
1430:
1414:
1412:
1394:
1360:
1339:fenfluramine
1336:
1331:
1327:
1309:
1298:
1294:fenfluramine
1255:
1246:Values are K
1228:
1225:
1207:
1204:
1170:
1167:
1149:
1146:
1066:Pharmacology
1056:erythromycin
1052:ketoconazole
1045:
1039:—as well as
1010:
1007:Interactions
997:
975:, fever and
958:
947:
939:
927:side effects
924:
909:
906:Side effects
838:Hypertension
788:
776:
773:Medical uses
768:
746:
693:
689:
688:
677:
288:Elimination
186:Legal status
180:Legal status
45:
9570:Venlafaxine
9535:Pronethalol
9505:Methoxamine
9435:Dizocilpine
9430:Diphenidine
9405:Amidephrine
9366:-Octopamine
9303:Metaraminol
9270:(Droxidopa)
9216:Epinephrine
9206:Dimetofrine
9052:Stimulants:
9031:Stimulants:
8859:Brephedrone
8849:Amfepramone
8801:Stimulants:
8783:Cericlamine
8764:Phentermine
8744:Clortermine
8731:Stimulants:
8511:Sibutramine
8496:Prenylamine
8431:Oxifentorex
8383:Metaraminol
8323:Fenproporex
8294:Fencamfamin
8274:Clobenzorex
8240:Amphetamine
8197:Stimulants:
7938:Stimulants:
7896:Macromerine
7440:Adrenergics
7367:Valbenazine
7357:Rose bengal
7302:Deserpidine
7273:amphetamine
7223:levorphanol
7167:Dextrorphan
7120:ziprasidone
7102:pheniramine
7037:Lofepramine
7017:Desipramine
6966:Tesofensine
6956:Sibutramine
6931:Perafensine
6891:JNJ-7925476
6886:Indatraline
6831:Dasotraline
6801:Amifitadine
6780:Venlafaxine
6760:Milnacipran
6659:Etoperidone
6639:Seproxetine
6629:Pirandamine
6609:Omiloxetine
6589:Fluvoxamine
6549:Cericlamine
6539:Alaproclate
6486:levorphanol
6415:ziprasidone
6397:pheniramine
6369:Setiptiline
6354:Maprotiline
6313:Lofepramine
6293:Desipramine
6242:Tesofensine
6232:Sibutramine
6207:Perafensine
6167:JNJ-7925476
6162:Indatraline
6107:Dasotraline
6077:Amifitadine
6056:Venlafaxine
6031:Milnacipran
5960:Nomifensine
5925:Fencamfamin
5854:Lortalamine
5844:Edivoxetine
5834:Ciclazindol
5829:Alseroxylon
5777:Venlafaxine
5757:Tametraline
5747:Sibutramine
5722:Perafensine
5702:Nomifensine
5632:Indatraline
5607:Fencamfamin
5582:DOV-216,303
5577:DOV-102,677
5537:Dasotraline
5532:Ciclazindol
5490:Armodafinil
5485:Amifitadine
5434:Tesofensine
5242:Difemetorex
5072:from market
5015:brexanolone
4929:risperidone
4826:Moclobemide
4808:Reversible:
4768:Reversible:
4691:Iproclozide
4626:Setiptiline
4621:Mirtazapine
4611:Maprotiline
4568:Propizepine
4553:Noxiptiline
4538:Metapramine
4528:Lofepramine
4498:Dimetacrine
4488:Desipramine
4361:Flupentixol
4346:Etryptamine
4331:Amisulpride
4326:Agomelatine
4272:Etoperidone
4249:Setiptiline
4244:Mirtazapine
4216:Nomifensine
4173:Atomoxetine
4150:Venlafaxine
4140:Milnacipran
4082:Fluvoxamine
3961:from market
3910:Metreleptin
3846:Mitratapide
3841:Dirlotapide
3771:Tirzepatide
3761:Semaglutide
3756:Retatrutide
3741:Liraglutide
3730:Ecnoglutide
3725:Danuglipron
3655:Ibipinabant
3642:antagonists
3640:Cannabinoid
3626:Tesofensine
3621:Sibutramine
3551:Difemetorex
3535:+naltrexone
3521:Atomoxetine
3490:Terbutaline
3465:Clenbuterol
3431:+topiramate
3427:Phentermine
3382:Fenproporex
3342:Clortermine
3332:Clobenzorex
3302:Amphetamine
3297:Amfepramone
3110:22 November
2825:16 December
2682:2437/111825
1732:(in German)
1494:Ralph Nader
1472:Schedule IV
1400:monohydrate
1290:amphetamine
1268:(by ~73%),
1116:Sibutramine
969:hematemesis
954:paresthesia
885:gland with
779:weight loss
761:Schedule IV
738:Philippines
716:along with
690:Sibutramine
604: g·mol
553:100.130.097
358:766462-77-5
353:106650-56-0
318:Identifiers
222:Schedule IV
96:MedlinePlus
69:Other names
60:Trade names
21:Sibutramine
9631:Stimulants
9591:Anorectics
9585:Categories
9540:Salbutamol
9475:Hexapradol
9455:Etafedrine
9450:Ephenidine
9445:Dopexamine
9440:Dobutamine
9420:Denopamine
9410:Arbutamine
9384:Synephrine
9318:Methyldopa
9313:Metirosine
9261:(Levodopa)
9251:Isoetarine
9236:Fenclonine
9226:Etilefrine
9140:Prolintane
8971:Mephedrone
8934:Radafaxine
8924:Pentedrone
8904:Methedrone
8864:Buphedrone
8854:Benzedrone
8793:Cathinones
8705:Selegiline
8695:Amiflamine
8491:Pholedrine
8441:Ortetamine
8436:Oxilofrine
8368:Lefetamine
8358:Iofetamine
8343:Furfenorex
8338:Formetorex
8328:Flucetorex
8259:Benfluorex
8230:Amfecloral
8225:Alfetamine
8098:D-Deprenyl
8015:Lophophine
7926:Psi-2C-T-4
7921:Proscaline
7891:Jimscaline
7416:SoRI-20041
7409:SoRI-20040
7337:Ketanserin
7264:Amiodarone
7227:tapentadol
7187:Mesembrine
7157:Delucemine
7134:esketamine
7047:Pipofezine
7032:Imipramine
6951:SEP-228432
6946:SEP-228431
6916:Nefazodone
6901:Liafensine
6871:Fezolamine
6861:DOV-216303
6856:DOV-102677
6811:Bicifadine
6806:Ansofaxine
6745:Eclanamine
6740:Duloxetine
6725:Bicifadine
6699:Vilazodone
6669:Lubazodone
6664:Litoxetine
6649:Zimelidine
6644:Sertraline
6619:Paroxetine
6614:Panuramine
6584:Fluoxetine
6579:Femoxetine
6559:Dapoxetine
6554:Citalopram
6478:tapentadol
6457:Nefazodone
6440:Ephenidine
6435:Dopexamine
6318:Melitracen
6308:Imipramine
6227:SEP-228432
6222:SEP-228431
6192:Nefazodone
6177:Liafensine
6147:Fezolamine
6137:DOV-216303
6132:DOV-102677
6087:Bicifadine
6082:Ansofaxine
6041:Nafenodone
6016:Eclanamine
6011:Duloxetine
5970:Radafaxine
5950:Manifaxine
5935:Lefetamine
5910:Amineptine
5894:Viloxazine
5869:Reboxetine
5864:Nisoxetine
5742:Sertraline
5732:Radafaxine
5717:Oroxylin A
5662:Manifaxine
5652:Liafensine
5642:Lefetamine
5622:GYKI-52895
5612:Fezolamine
5597:Esketamine
5592:Ephenidine
5515:BTS 74,398
5505:Ansofaxine
5500:Amineptine
5379:FP-β-CPPIT
5374:FE-β-CPPIT
5313:Prolintane
5206:Vanoxerine
5201:Nefazodone
5047:Tryptophan
5019:zuranolone
4925:quetiapine
4921:olanzapine
4917:lurasidone
4871:Selegiline
4861:-selective
4841:Toloxatone
4836:Tetrindole
4831:Pirlindole
4811:Eprobemide
4801:-selective
4781:Bifemelane
4771:Caroxazone
4731:Phenelzine
4716:Mebanazine
4696:Iproniazid
4583:Tianeptine
4563:Pipofezine
4533:Melitracen
4513:Imipramine
4493:Dibenzepin
4453:Amineptine
4401:Tianeptine
4386:Pivagabine
4381:Oxaflozane
4341:Esketamine
4305:Vilazodone
4277:Nefazodone
4206:Amineptine
4183:Viloxazine
4178:Reboxetine
4130:Duloxetine
4102:Zimelidine
4097:Sertraline
4092:Paroxetine
4077:Fluoxetine
4067:Citalopram
3935:Zonisamide
3925:Topiramate
3915:Naltrexone
3895:Bimagrumab
3866:Uncouplers
3856:Simmondsin
3836:Cetilistat
3820:Lorcaserin
3720:Cotadutide
3715:Cinchonine
3680:Taranabant
3675:Surinabant
3670:Rosonabant
3665:Rimonabant
3571:Manifaxine
3526:Benfluorex
3485:Synephrine
3392:Furfenorex
3287:Amfecloral
3260:Stimulants
3247:Anorectics
3166:2018-10-14
3081:2018-01-23
3052:2011-03-25
2982:2018-01-23
2927:2010-01-24
2600:2007-04-29
2570:2022-12-12
2331:2007-04-29
2277:6 February
2139:2007-04-29
2039:2019-12-16
1957:2017-10-08
1897:2010-01-22
1868:2010-12-22
1811:2012-11-06
1790:2011-03-15
1769:2010-11-08
1718:2011-05-21
1674:2014-10-06
1645:2023-08-16
1614:References
1464:Nottingham
1125:943–1,200
1050:, such as
1017:selegiline
985:hemiplegia
981:chest pain
856:Stroke or
753:Nottingham
609:3D model (
597:Molar mass
503:ChEMBL1419
463:WV5EC51866
434:ChemSpider
394:IUPHAR/BPS
344:CAS Number
327:IUPAC name
282:-mediated)
271:Metabolism
9520:PARGY-LAD
9415:Cafedrine
9374:-Tyramine
9328:Nordefrin
9308:Metaterol
9293:-Tyramine
9285:-Tyrosine
9241:Ibopamine
9130:Naphyrone
8961:Methylone
8929:Pentylone
8874:Cathinone
8869:Bupropion
8712:-Deprenyl
8378:Mefenorex
8348:Gepefrine
8299:Fencamine
8284:Ephedrine
8220:Acridorex
7947:Hordenine
7906:Mescaline
7799:2C-T-22.5
7537:25N-NBOMe
7532:25I-NBOMe
7527:25D-NBOMe
7522:25C-NBOMe
7517:25B-NBOMe
7429:See also:
7404:SoRI-9804
7352:Reserpine
7322:GBR-12935
7317:Efavirenz
7237:Roxindole
7215:methadone
7202:N-Me-5-HT
7172:Efavirenz
7130:3-MeO-PCP
7073:Amoxapine
6941:Pridefine
6911:Naphyrone
6775:Tofenacin
6694:Trazodone
6684:SB-649915
6679:Quipazine
6674:LY-393558
6599:Ifoxetine
6594:Indalpine
6470:methadone
6359:Mianserin
6349:Amoxapine
6217:Pridefine
6187:Naphyrone
6051:Tofenacin
6001:CP-39,332
5920:Fencamine
5915:Bupropion
5884:Tandamine
5879:Talsupram
5839:Daledalin
5737:Rimcazole
5727:Pridefine
5692:Modafinil
5617:Fluorenol
5587:Efavirenz
5520:Bupropion
5480:Adrafinil
5444:Tropoxane
5334:Altropane
5331:Tropanes:
5308:Naphyrone
5272:Pipradrol
5191:GBR-13098
5186:GBR-13069
5181:GBR-12935
5176:GBR-12783
5082:Phase III
5070:Withdrawn
4935:Buspirone
4821:Minaprine
4756:Tedizolid
4751:Safrazine
4726:Octamoxin
4721:Nialamide
4711:Linezolid
4706:Isoniazid
4616:Mianserin
4558:Opipramol
4523:Iprindole
4503:Dosulepin
4468:Amoxapine
4424:Tricyclic
4282:Trazodone
4239:Mianserin
4211:Bupropion
4145:Tofenacin
4087:Indalpine
4036:Specific
3971:Phase III
3959:Withdrawn
3905:Metformin
3890:Beloranib
3735:Exenatide
3660:Otenabant
3650:Drinabant
3606:Pipradrol
3531:Bupropion
3495:Yohimbine
3470:Ephedrine
3460:Albuterol
3407:Mefenorex
3357:Ephedrine
3322:Cathinone
3071:drugs.com
2972:drugs.com
2952:March 26,
1947:drugs.com
1927:8 October
1419:biofluids
1391:Chemistry
1286:anorectic
1270:serotonin
1122:350–5,451
1119:298–2,800
1033:ergolines
1031:—such as
1029:migraines
899:lactating
878:disorders
843:Existing
829:centrally
827:or other
730:withdrawn
309:Excretion
290:half-life
137:Routes of
110:Pregnancy
88:Monograph
82:Drugs.com
72:BTS-54524
9621:Prodrugs
9525:Phenibut
9211:Dopamine
9192:Ciladopa
9182:a-Me-TRA
9022:Eutylone
9012:Butylone
8956:Ethylone
8951:Butylone
8941:3,4-DMMC
8889:Eutylone
8839:4-MeMABP
8759:Pentorex
8749:Etolorex
8739:Cloforex
8516:Tiflorex
8408:Morforex
8333:Fludorex
8088:Beatrice
7881:Escaline
7391:Luteolin
7342:Lobeline
7332:Ibogaine
7231:tramadol
7177:Hypidone
7138:ketamine
7116:loxapine
6976:Tropanes
6906:Mazindol
6896:JZ-IV-10
6730:CP-39332
6689:TGBA01AD
6482:tramadol
6425:ketamine
6411:loxapine
6252:Tropanes
6182:Mazindol
6172:JZ-IV-10
5874:Talopram
5859:Mazindol
5824:Amedalin
5682:Metaphit
5677:Mesocarb
5667:Mazindol
5637:Ketamine
5439:Troparil
5196:JJC8-088
5008:GABAkine
4686:Benmoxin
4642:Tiazesim
4366:Ketamine
4351:Gepirone
3930:ZGN-1061
3851:Orlistat
3698:and / or
3576:Mazindol
3516:Aminorex
3422:Pentorex
3387:Fludorex
3372:Etolorex
3337:Cloforex
3186:Archived
3160:Archived
3075:Archived
3046:Archived
3036:Pope C.
2976:Archived
2946:Archived
2921:Archived
2892:Archived
2876:19471631
2819:Archived
2779:Archived
2691:20818901
2639:Archived
2635:CBS News
2594:Archived
2564:Archived
2523:23359461
2515:16723754
2479:17072906
2435:10844103
2375:24789264
2367:19693007
2268:Archived
2244:19505264
2195:20553857
2187:12119986
2110:33454957
2033:Archived
2006:24787523
1951:Archived
1891:Archived
1887:BBC News
1830:Archived
1738:Archived
1691:Archived
1639:Archived
1575:orlistat
1351:receptor
1345:for the
1343:affinity
1274:dopamine
1262:reuptake
1081:Compound
1037:triptans
973:jaundice
961:seizures
883:prostate
871:glaucoma
742:Thailand
722:exercise
680:(verify)
414:DrugBank
201:Class B2
156:ATC code
148:capsules
112:category
9565:UWA-101
9530:PRO-LAD
9460:ETH-LAD
9221:Epinine
9177:a-Me-DA
9100:4-MePPP
9095:4-MePHP
9090:4-MePBP
9002:Ariadne
8780:Others:
8690:3,4-DCA
8687:Others:
8638:2,3-MDA
8623:6-MAPDB
8588:5-MAPDB
8269:Cathine
8193:ZDCM-04
8178:Psi-DOM
8163:Ganesha
8029:Others:
7844:2C-T-33
7839:2C-T-32
7834:2C-T-31
7829:2C-T-30
7824:2C-T-28
7819:2C-T-27
7814:2C-T-25
7809:2C-T-24
7804:2C-T-23
7794:2C-T-22
7789:2C-T-21
7784:2C-T-20
7779:2C-T-19
7774:2C-T-18
7769:2C-T-17
7764:2C-T-16
7759:2C-T-15
7754:2C-T-14
7749:2C-T-13
7744:2C-T-12
7739:2C-T-11
7734:2C-T-10
7549:2C-B-AN
7327:GZ-793A
7271:(e.g.,
7209:(e.g.,
7207:Opioids
7128:(e.g.,
7114:(e.g.,
7080:(e.g.,
7068:A-80426
7065:Others:
7027:Doxepin
6980:cocaine
6978:(e.g.,
6926:NS-2359
6921:Nefopam
6876:HDMP-28
6866:EXP-561
6826:Cocaine
6755:McN5652
6634:RTI-353
6464:(e.g.,
6462:Opioids
6423:(e.g.,
6409:(e.g.,
6387:(e.g.,
6382:Others:
6303:Doxepin
6256:cocaine
6254:(e.g.,
6202:NS-2359
6197:Nefopam
6152:HDMP-28
6142:EXP-561
6102:Cocaine
6026:McN5652
5945:LR-5182
5707:NS-2359
5697:Nefopam
5657:LR-5182
5602:EXP-561
5477:Others:
5429:RTI-336
5424:RTI-229
5419:RTI-177
5414:RTI-150
5409:RTI-126
5404:RTI-121
5399:RTI-113
5394:RTI-112
5354:Cocaine
5252:HDMP-28
5171:DBL-583
4940:Lithium
4508:Doxepin
4040:and/or
3710:AMG 133
3499:Yohimbe
3475:Ephedra
3362:Ephedra
3317:Cathine
3156:NPR.org
2917:CNN.com
2867:2680571
2459:Bibcode
2307:9758240
2235:2695569
2101:8094237
2029:fda.gov
1998:2851857
1378:isozyme
1314:to two
1312:prodrug
1282:satiety
1041:opioids
989:dyspnea
920:strokes
876:Seizure
714:obesity
710:adjunct
694:Meridia
570:Formula
423:DB01105
369:PubChem
276:Hepatic
261:& M
172:)
166: (
164:A08AA10
125: C
102:a601110
9480:IP-LAD
9400:AL-LAD
9172:6-OHDA
8707:(also
8700:DiFMDA
8618:6-MAPB
8608:6-EAPB
8598:6-APDB
8583:5-MAPB
8573:5-EAPB
8568:5-APDB
8173:MMDA-2
8073:3C-MAL
8025:MDMPEA
7876:DESOXY
7854:2C-TFM
7849:2C-TFE
7729:2C-T-9
7724:2C-T-8
7719:2C-T-7
7714:2C-T-6
7709:2C-T-5
7704:2C-T-4
7699:2C-T-3
7694:2C-T-2
7669:2C-O-4
7659:2C-NH2
7634:2C-G-N
7629:2C-G-6
7624:2C-G-5
7619:2C-G-4
7614:2C-G-3
7609:2C-G-2
7604:2C-G-1
7381:Others
6936:PRC200
6881:HP-505
6624:PIM-35
6212:PRC200
6157:HP-505
5965:O-2172
5712:O-2172
5389:RTI-55
5065:WHO-EM
4778:Mixed:
4635:Others
4319:Others
4227:NaSSAs
3954:WHO-EM
3883:Others
3805:5-HT2C
3782:DACRAs
2874:
2864:
2689:
2521:
2513:
2477:
2433:
2396:
2373:
2365:
2305:
2242:
2232:
2193:
2185:
2108:
2098:
2004:
1996:
1627:Anvisa
1559:et al.
1385:amines
1381:CYP3A4
1371:plasma
1250:(nM).
1048:CYP3A4
977:rigors
965:melena
931:nausea
853:(TIA))
635:SMILES
602:279.85
494:ChEMBL
483:D08513
280:CYP3A4
220:
199:
9515:MT-45
9268:-DOPS
9259:-DOPA
9200:-DOPA
9167:6-FNE
9110:MOPVP
9105:MOPPP
9080:MDPPP
9075:MDPBP
9070:α-PVP
9065:α-PPP
9060:α-PHP
9055:α-PBP
8997:4-MAB
8992:4-CAB
8946:3-MMC
8844:4-MPD
8834:4-MEC
8829:4-FMC
8824:4-EMC
8819:4-CMC
8814:4-BMC
8804:3-FMC
8776:MDMPH
8673:MMDMA
8653:MDHMA
8593:6-APB
8563:5-APB
8558:4-MTA
8553:4-MMA
8543:4-FMA
8215:3-FMA
8205:2-FMA
8158:DOTFM
8113:DMMDA
8108:DMCPA
8083:Aleph
8063:3C-BZ
8058:3C-AL
8037:DMPEA
8020:MDPEA
7931:TCB-2
7901:MEPEA
7859:2C-YN
7684:2C-SE
7679:2C-Ph
7649:2C-iP
7589:2C-EF
7574:2C-CP
7569:2C-CN
7559:2C-Bu
7554:2C-Bn
7252:VMATs
5464:WF-33
5459:WF-31
5454:WF-23
5449:WF-11
5035:5-HTP
4599:TeCAs
4260:SARIs
4194:NDRIs
4113:SNRIs
4055:SSRIs
3940:Water
3815:5-HTP
3690:GLP-1
3509:Other
3197:from
3132:MSNBC
2900:WebMD
2756:(PDF)
2749:(PDF)
2732:(PDF)
2709:(PDF)
2657:(PDF)
2519:S2CID
2371:S2CID
2271:(PDF)
2264:(PDF)
2191:S2CID
2002:S2CID
1862:(PDF)
1855:(PDF)
1460:Boots
1445:g/L.
1235:4,300
1177:9,200
993:edema
860:(TIA)
803:mania
749:Boots
655:InChI
611:JSmol
9125:MPPP
9120:MPHP
9115:MPBP
9085:MDPV
9027:MBDB
9017:EBDB
8809:4-MC
8771:MDPH
8663:MDOH
8648:MDEA
8613:6-IT
8578:5-IT
8548:4-MA
8538:4-FA
8481:PMMA
8476:PMEA
8461:PFMA
8210:3-FA
8200:2-FA
8188:TeMA
8168:MMDA
8153:DOPR
8133:DOET
8128:DOEF
8078:3C-P
8068:3C-E
7864:2C-V
7689:2C-T
7674:2C-P
7664:2C-O
7654:2C-N
7644:2C-I
7639:2C-H
7599:2C-G
7594:2C-F
7584:2C-E
7579:2C-D
7564:2C-C
7544:2C-B
7292:AZIK
7281:MDMA
6770:PPPA
6513:SRIs
6502:SERT
6046:PPPA
5803:NRIs
5303:MDPV
5150:DRIs
5001:SAMe
4441:TCAs
4426:and
4161:NRIs
4023:N06A
3397:Khat
3112:2012
2954:2010
2872:PMID
2827:2019
2787:2017
2687:PMID
2511:PMID
2475:PMID
2431:PMID
2394:ISBN
2363:PMID
2303:PMID
2279:2016
2240:PMID
2183:PMID
2106:PMID
1994:PMID
1929:2010
1838:2014
1590:MHRA
1403:salt
1347:5-HT
1292:and
1220:8.9
1183:180
1086:SERT
1054:and
1035:and
991:and
918:and
720:and
718:diet
474:KEGG
454:UNII
443:5021
403:2586
383:5210
234:data
144:Oral
78:AHFS
9135:PEP
9007:BDB
8909:NEB
8683:TAP
8633:IAP
8628:EDA
8471:PMA
8466:PIA
8456:PFA
8451:PCA
8446:PBA
8403:MMA
8183:TMA
8148:DON
8143:DOM
8138:DOI
8123:DOC
8118:DOB
8103:DMA
8032:BOH
7287:APP
5792:NET
5510:BTQ
5349:CFT
5139:DAT
4964:),
4852:MAO
4792:MAO
4293:SMS
3694:GIP
3271:and
3251:A08
2862:PMC
2854:doi
2850:106
2721:doi
2677:hdl
2669:doi
2665:363
2560:FDA
2503:doi
2467:doi
2423:doi
2419:397
2355:doi
2230:PMC
2222:doi
2175:doi
2096:PMC
2088:doi
1986:doi
1462:in
1421:by
1264:of
1241:12
1214:140
1199:45
1180:870
1162:12
1141:49
1106:DAT
1096:NET
751:in
519:EPA
373:CID
169:WHO
9587::
8315:,
8246:,
7454:•
7450:•
7446:•
7442:•
7438:•
7434:•
7411:;
7279:,
7275:,
7229:,
7225:,
7221:,
7217:,
7213:,
7144:,
7140:,
7136:,
7132:,
7118:,
7104:,
7100:,
7096:,
7092:,
7088:,
7084:,
6484:,
6480:,
6476:,
6472:,
6468:,
6427:,
6413:,
6399:,
6395:,
6391:,
5078::
5017:,
4972:))
4968:(T
4960:(T
4946:,
4927:,
4923:,
4919:,
4915:,
4911:,
3967::
3696:,
3692:,
3158:.
3154:.
3129:.
3098:.
3073:.
3069:.
3044:.
3040:.
2999:.
2974:.
2970:.
2915:.
2898:,
2870:.
2860:.
2848:.
2844:.
2777:.
2773:.
2717:27
2715:.
2711:.
2685:.
2675:.
2663:.
2659:.
2633:.
2592:.
2588:.
2562:.
2558:.
2546:^
2517:.
2509:.
2499:12
2497:.
2473:.
2465:.
2455:20
2453:.
2429:.
2417:.
2369:.
2361:.
2351:86
2349:.
2299:22
2297:.
2252:^
2238:.
2228:.
2216:.
2212:.
2189:.
2181:.
2169:.
2118:^
2104:.
2094:.
2082:.
2078:.
2048:^
2031:.
2027:.
2014:^
2000:.
1992:.
1982:12
1980:.
1966:^
1949:.
1945:.
1915:.
1885:.
1744:.
1662:.
1604:.
1405:.
1353:.
1349:2B
1318:,
1238:62
1217:13
1196:15
1193:20
1156:44
1138:20
1135:15
1062:.
995:.
983:,
979:,
971:,
967:,
952:,
933:,
823:,
797:,
740:,
587:Cl
584:26
578:17
216:US
208:CA
195:BR
121:AU
9546:)
9542:(
9372:p
9364:p
9347:m
9345:(
9334:)
9330:(
9291:m
9283:L
9275:L
9266:L
9257:L
9198:D
8714:)
8710:D
8419:L
8394:)
8319:)
8311:(
8250:)
8242:(
7998:p
7990:o
7982:N
7974:m
7490:e
7483:t
7476:v
7283:)
7233:)
7148:)
7122:)
7108:)
6982:)
6519:)
6510:(
6488:)
6431:)
6417:)
6403:)
6258:)
5809:)
5800:(
5156:)
5147:(
5122:e
5115:t
5108:v
5037:)
5021:)
5013:(
5003:)
4970:4
4962:3
4956:(
4950:)
4942:(
4931:)
4907:(
4854:B
4794:A
4025:)
4021:(
4011:e
4004:t
3997:v
3796:)
3792:(
3773:†
3767:)
3763:(
3737:†
3567:)
3563:(
3537:)
3533:(
3501:)
3497:(
3433:)
3429:(
3253:)
3249:(
3245:/
3235:e
3228:t
3221:v
3169:.
3114:.
3084:.
3055:.
2985:.
2956:.
2930:.
2878:.
2856::
2829:.
2789:.
2723::
2693:.
2679::
2671::
2603:.
2573:.
2525:.
2505::
2481:.
2469::
2461::
2437:.
2425::
2402:.
2377:.
2357::
2334:.
2309:.
2281:.
2246:.
2224::
2218:8
2197:.
2177::
2171:1
2142:.
2112:.
2090::
2084:1
2042:.
2008:.
1988::
1960:.
1931:.
1900:.
1871:.
1840:.
1814:.
1793:.
1772:.
1721:.
1677:.
1648:.
1443:μ
1431:μ
1425:-
1415:N
1332:S
1328:R
1248:i
1229:S
1227:(
1208:R
1206:(
1171:S
1169:(
1159:4
1150:R
1148:(
613:)
590:N
581:H
575:C
521:)
517:(
303:)
301:2
297:1
278:(
265:)
263:2
259:1
218::
197::
150:)
146:(
123::
80:/
46:S
44:(
Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
