27:
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According to the organization site, its goal is to "help build the industry that will cure the diseases of aging". It funds research and uses outreach and education in order to expedite the various regenerative medicine research programs that go together to make the SENS project. The foundation also
252:
supported the SENS program, many contended that the ultimate goals of de Grey's programme were too speculative given the state of technology and referred to it as "fantasy rather than science". By the mid-2010s, the rejuvenation approach gained traction with multiple startup companies created from
257:
pledged another €300 million for rejuvenation biotechnology startup companies. In 2021, Underdog
Pharmaceuticals, a startup company spun out from a research program at SENS Research Foundation, was awarded an Innovation Passport from the United Kingdom Medicines and Healthcare products Regulatory
258:
Agency, which intends to streamline the approval program of promising therapies. In August 2021, Aubrey de Grey was suspended from the foundation. The CEO of the SENS Research
Foundation, Jim O’Neill left in the preceding July, at the same time de Grey was suspended.
682:
and their common activities, during reading articles and public reports there are sometimes misunderstanding about their budgets, directions and amounts of donations which can be distributed between these organizations for various purposes.
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In 2011, Aubrey de Grey inherited $ 16.5 million on the death of his mother. Of this he assigned $ 13 million to fund SENS research, which by 2013 had the effect of roughly doubling the SRF yearly budget to $ 4 million.
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Underdog
Pharmaceuticals received an Innovation Passport, an accelerated regulatory pathway from the UK government for promising therapies, for a small molecule drug to treat
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The
Degradation of Tau Aggregates project seeks to remove aggregated tau proteins, which are part of age-related cognitive decline, Alzheimer's, and other tauopathies.
1318:
707:
in 2019 its income was $ 2,683,611 and expenses $ 4,361,258 ($ 2,331,364 on research, $ 859,222 on education, $ 642,056 on outreach, $ 582,616 on administration).
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in 2017 its income was $ 7,871,530 and expenses $ 3,915,682 ($ 2,146,412 on research, $ 920,533 on education, $ 172,380 on outreach, $ 676,534 on administration).
1990:
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The mitochondrial transplantation project aims to take advantage of the body's natural process of mitochondrial exchange for healthy mitochondrial transfusion.
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1974:
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and Haseeb
Qureshi donated a total of $ 150,000 to SENS Research Foundation to combat aging and aging-related diseases at the choice of users of
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1259:"Fight Aging! Invests in Ichor Therapeutics to Support Development of a SENS Damage Repair Therapy for Macular Degeneration"
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225:. It was founded in 2009, located in Mountain View, California, US. The organization publishes its reports annually.
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has also taken part in and/or selectively funded extramural research at various other institutions, including
1479:[«King of Ethereum» Vitalik Buterin: the best thing to donate money for is the fight against aging].
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donated $ 2 million to SENS in 2017–18, that's in addition to $ 1 million donated to
Methuselah Foundation.
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The SENS Research
Foundation (SRF) pursues research projects that correspond to the seven categories of
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Oisin
Biotechnologies (SENS seed-funded startup) has a precise targeting technology, which is based on
1343:
1291:"SENS Research Foundation & Underdog Pharmaceuticals jointly awarded $ 252,000 NIA research grant"
1916:
1659:
1572:
1477:""Король Эфириума" Виталик Бутерин: лучшее, на что стоит жертвовать деньги — это борьба со старением"
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978:
Michael Greve
Announces a New €300 Million Fund for Investment in Rejuvenation Biotechnology Startups
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Before the foundation was founded in March 2009, the SENS research program was mainly pursued by the
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1421:"The Pineapple Fund Donates Millions to the Organ Preservation Alliance and Methuselah Foundation"
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2009:
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Michael Greve, founder of
Forever Healthy, commits €300 million to advance rejuvenation startups
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OncoSENS's solution is to preemptively remove the genes for the telomere-lengthening machinery.
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cofounder Michael Antonov donated $ 1 million, of which $ 600,000 was a matching donation.
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1435:"SENS Research Foundation Receives $ 2.4 Million Ethereum Donation From Vitalik Buterin"
1195:"Stable nuclear expression of ATP8 and ATP6 genes rescues a mtDNA Complex V null mutant"
1966:
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960:
912:
888:"Science fact and the SENS agenda. What can we reasonably expect from ageing research?"
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1319:"Revel Pharmaceuticals Finally Seed Funded to Develop Glucosepane Cross-Link Breakers"
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In addition to research undertaken in-house at the Research Center in Mountain View,
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907:
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1245:"Engineering New Mitochondrial Genes to Restore Mitochondrial Function (MitoSENS)"
1156:"Selective Ablation of Senescent and Malignant Cells using Apoptotic Gene Therapy"
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626:
2016:
1941:
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1273:"Kizoo portfolio company Underdog awarded 'Innovation Passport' by UK Regulators"
1001:"Kizoo portfolio company Underdog awarded 'Innovation Passport' by UK Regulators"
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1450:"Vitalik Buterin: The Best Thing to Donate Money to is The Fight Against Aging"
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When the SENS rejuvenation approach was announced in the 2000s, while some
26:
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donated $ 2.4 million in 2018. Then in 2020 Vitalik Buterin together with
1815:
1795:
1634:
1589:
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1211:
935:
Holliday R (April 2009). "The extreme arrogance of anti-aging medicine".
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by clearing arterial plaques. Underdog and SRF received a grant from the
291:
242:
1361:"Internet Entrepreneur Jason Hope Pledges A Donation To SENS Foundation"
785:"Women In Longevity And The Renaissance Of The SENS Research Foundation"
2023:
1856:
1684:
704:
in 2018 – unclear, the annual report does not contain this information.
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Graphs are unavailable due to technical issues. There is more info on
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Graphs are unavailable due to technical issues. There is more info on
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genes was successful. Research was published in the peer-reviewed
1871:
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Revel Pharmaceuticals is developing therapeutics that can cleave
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1614:
1022:"Anti-aging foundation's CEO left amid probe of Aubrey de Grey"
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1881:
886:
Warner H; Anderson J; Austad S; et al. (November 2005).
222:
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Owing to the close relationship between SENS Foundation and
1092:"Functional Neuron Replacement to Rejuvenate the Neocortex"
413:
409:
1173:"MitoSENS: Preventing Damage from Mitochondrial Mutations"
885:
686:
On December 9, 2010, Jason Hope, an entrepreneur based in
188:
1534:
1437:(Press release). SENS Research Foundation. 2018-02-02.
1109:"Plasmid based senolytics from Oisín Biotechnologies"
365:
therapy results in 75–90% reduction in tumor in mice.
1519:
Michael Antonov Foundation: SENS Research Foundation
440:
Ichor Therapeutics is developing repair therapy for
335:seeking to replenish and regenerate the neocortex.
2081:
1332:SENS Research Foundation Research Advisory Board
670:
506:
1991:Lifespan: Why We Age – and Why We Don't Have To
1695:Strategies for engineered negligible senescence
1193:Boominathan, Amutha; et al. (2016-09-04).
1016:
1014:
281:Strategies for engineered negligible senescence
1153:
1571:
1557:
1344:"SENS Research Foundation 2022 Annual Report"
870:"SENS Research Foundation 2020 Annual Report"
864:
862:
850:"SENS Research Foundation 2019 Annual Report"
844:
842:
830:"SENS Research Foundation 2018 Annual Report"
824:
822:
820:
808:"SENS Research Foundation 2011 Annual Report"
802:
800:
2105:Non-profit organizations based in California
1474:
1011:
357:from Oisin Biotechnologies, which is a SENS
1336:
1130:"Systemic Senolysis in Naturally Aged Mice"
782:
306:Description and related spin-off companies
1564:
1550:
1305:"Catalyzing Degradation of Tau Aggregates"
934:
859:
839:
817:
797:
536:
25:
1650:Index of topics related to life extension
1220:
1210:
911:
500:
541:The SENS Research Foundation's research
928:
879:
2082:
1495:"Effective Altruism: Giving in Crypto"
1452:. LIFE EXTENSION ADVOCACY FOUNDATION.
1545:
1447:
1103:
1101:
1382:"Interview with Aubrey de Grey, PhD"
783:Zhavoronkov, Alex (April 17, 2023).
755:Buck Institute for Research on Aging
640:
611:
285:
1483:(in Russian). Komsomolskaya Pravda.
333:Albert Einstein College of Medicine
13:
1275:. 8 September 2021. Archived from
1098:
1071:"RepleniSENS:Replacing Lost Cells"
1003:. 8 September 2021. Archived from
760:Life Extension Advocacy Foundation
14:
2121:
2110:Organizations established in 2009
1526:
604:
331:SRF helps fund the Hebert lab at
267:conducts its own student program
1708:
1448:Elena, Milova (March 20, 2018).
1047:"About SENS Research Foundation"
690:, pledged a $ 500,000 donation.
645:
616:
455:to pursue this research further.
253:SENS research findings. In 2021
1725:Timeline of senescence research
1512:
1501:
1487:
1468:
1456:from the original on 2018-03-22
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1413:
1409:Bitcoin Transaction f0aa1cc5bc…
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1398:Bitcoin Transaction 10dd3b4bb1…
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408:Initial proof of concept using
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971:
776:
697:According SRF annual reports,
490:advanced glycation end-product
1:
1154:Dr. John Lewis (2018-10-11).
770:
462:Extracellular waste products
453:National Institutes of Health
432:Intracellular waste products
2100:Life extension organizations
2095:Biogerontology organizations
733:as a result of open voting.
217:work for the application of
7:
1852:Alliance for Aging Research
1508:2020 End of Year Fundraiser
1475:Анна ДОБРЮХА (2018-03-20).
1423:. Fight Aging!. 2018-01-29.
1321:. Fight Aging!. 2020-01-07.
1261:. Fight Aging!. 2016-08-15.
743:
274:
39:; 15 years ago
10:
2126:
1887:Gerontology Research Group
1175:. SENS Research Foundation
1073:. SENS Research Foundation
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228:
2061:
2001:
1950:
1927:MPI for Biology of Ageing
1829:
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1660:Longevity escape velocity
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1132:. YouTube. Archived from
949:10.1007/s10522-008-9170-6
183:
157:Maria Entraigues-Abramson
141:
131:
121:
97:
87:
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2090:Regenerative biomedicine
2038:Experimental Gerontology
1937:SENS Research Foundation
1161:. University of Alberta.
904:10.1038/sj.embor.7400555
342:Division-obsessed cells
261:
203:SENS Research Foundation
20:SENS Research Foundation
2010:Ageing Research Reviews
1655:List of aging processes
1386:Life Extension Magazine
537:Research advisory board
207:non-profit organization
16:Non-profit organization
1700:Transhumanist politics
1199:Nucleic Acids Research
575:María Blasco Marhuenda
501:Research collaboration
419:Nucleic Acids Research
372:Death-resistant cells
2052:Rejuvenation Research
2045:Neurobiology of Aging
1922:Methuselah Foundation
765:Methuselah Foundation
680:Methuselah Foundation
531:University of Arizona
235:Methuselah Foundation
219:regenerative medicine
563:William A. Haseltine
519:Cambridge University
478:Extracellular matrix
442:macular degeneration
403:Allotopic expression
1897:Immortalist Society
1645:Indefinite lifespan
1625:Free-radical theory
1605:Calorie restriction
1595:Anti-aging movement
688:Scottsdale, Arizona
547:Pedro J. J. Alvarez
523:University of Texas
311:Cell loss and cell
21:
1967:The First Immortal
1363:. December 9, 2010
1293:. 9 December 2021.
1212:10.1093/nar/gkw756
1051:Official SENS site
599:Vladimir Skulachev
515:Harvard University
327:tissue engineering
19:
2077:
2076:
1907:Insilico Medicine
1746:Eric R. Braverman
1690:Stem-cell therapy
1205:(19): 9342–9357.
727:Sam Bankman-Fried
667:
666:
638:
637:
498:
497:
384:' DNA expression.
303:Research program
286:Research programs
250:biogerontologists
211:research programs
199:
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148:Lisa Fabiny-Kiser
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1975:Fantastic Voyage
1766:Leonard Hayflick
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1094:. 25 March 2019.
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567:Brian K. Kennedy
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237:, co-founded by
215:public relations
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1892:Human Longevity
1837:2045 Initiative
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1821:Michael D. West
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595:Michael D. West
583:Nadia Rosenthal
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527:Rice University
511:Yale University
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449:atherosclerosis
382:senescent cells
292:cellular damage
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1279:on 2021-09-08.
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1007:on 2021-09-08.
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937:Biogerontology
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559:Judith Campisi
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1801:Durk Pearson
1786:Ray Kurzweil
1756:Laura Deming
1741:Bill Andrews
1680:Rejuvenation
1670:Nanomedicine
1630:Gene therapy
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1124:
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363:suicide gene
353:OncoSenX's (
317:RepleniSENS
289:
268:
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247:
232:
202:
200:
170:Michael Kope
162:Kevin Dewalt
154:(Chairman),
123:Area served
92:Rejuvenation
64:Michael Kope
1816:Roy Walford
1796:Liz Parrish
1635:Gerontology
721:co-founder
656:Phabricator
627:Phabricator
492:crosslinks.
480:stiffening
375:ApoptoSENS
359:seed-funded
243:David Gobel
2084:Categories
2062:Categories
2024:Aging Cell
1857:Altos Labs
1811:Sandy Shaw
1685:Senescence
1600:Biohacking
1573:Outline of
1367:2021-03-29
1179:2020-12-31
1140:2021-01-09
1115:2021-04-07
1077:2020-12-31
1056:2021-03-26
1032:2021-08-15
771:References
483:GlycoSENS
465:AmyloSENS
394:mutations
323:Stem cells
209:that does
143:Key people
109:California
68:Sarah Marr
1806:Mark Roth
1771:Saul Kent
1640:Glycation
1460:March 21,
1159:(lecture)
736:In 2020,
545:includes
435:LysoSENS
397:MitoSENS
361:startup)
345:OncoSENS
166:Jeff Hall
152:Bill Liao
82:501(c)(3)
60:Jeff Hall
2002:Journals
1620:Exercise
1610:Cryonics
1454:Archived
1231:27596602
957:18726707
922:16264422
744:See also
719:Ethereum
591:Jan Vijg
422:journal.
275:Research
98:Location
1872:BioViva
1481:Kp.ru -
1222:5100594
913:1371037
731:Twitter
658:and on
629:and on
355:spinout
313:atrophy
229:History
184:Website
52:Founder
44:2009-03
42: (
34:Founded
1994:(2019)
1986:(2007)
1978:(2004)
1970:(1998)
1962:(1982)
1877:Calico
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1583:Issues
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738:Oculus
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127:Global
2017:Aging
1951:Books
1882:ERIBA
1347:(PDF)
961:S2CID
873:(PDF)
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262:Goals
223:aging
205:is a
191:.sens
88:Focus
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1462:2018
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