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Respiratory tract infection

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probably reduces respiratory infections but not mortality. However, the combination of treatments cannot rule out the relevant contribution in the systemic component of the observed reduction of mortality. There is no sufficient evidence to recommend that antibiotics be used to prevent complications
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The CDC has reported that antibiotic prescription is high; 47 million prescriptions in the United States in 2018 were made for infections that do not need antibiotics to be treated with. It is recommended to avoid antibiotic use unless bacterial infections are severe, transmissible, or have a high
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help determine the functional residual capacity and total lung capacity. To discover whether or not to perform a set of advanced Pulmonary Function Testing will be based on abnormally high values in previous test results. A 2014 systematic review of clinical trials does not support routine rapid
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from an RTI of unknown cause in children under the age of 5 years old. High-quality clinical research in the form of randomized controlled trials assessed the effectiveness of Vitamin D, another review of poorer quality RCTs addressed the effectiveness of
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for preventing respiratory tract infections. Despite some uncertainty due to small study sizes, there is some evidence that exercise may reduce severity of symptoms but had no impact on number of episodes or number of symptom days per episode.
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measured in vitro, insufficient clinical evidence has been published to determine whether standard surgical masks and N95 filtering facepiece respirators are equivalent to preventing respiratory infections in healthcare workers.
495:. Several factors explain winter peaks in respiratory infections, including environmental conditions and changes in human behaviors. Viruses that cause respiratory infections are affected by environmental conditions like 1192: 433:
found that narrow-spectrum antibiotics, such as amoxicillin, are just as effective as broad-spectrum alternatives for treating acute respiratory tract infections in children, but have a lower risk of side effects.
343:(PFT) allows for the evaluation and assessment of airways, lung function, as well as specific benchmarks to diagnose an array of respiratory tract infections. Methods such as gas dilution techniques and 407:
and common respiratory tract infections. This is because antibiotics were developed to target features of bacteria that are not present in viruses, and so antibiotics are ineffective as
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utilization in children screened with rapid viral testing is 77% compared with controls. In 2013 researchers developed a breath tester that can promptly diagnose lung infections.
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viral testing to decrease antibiotic use for children in emergency departments. It is unclear if rapid viral testing in the emergency department for children with acute
636:"Applying psychological theories to evidence-based clinical practice: identifying factors predictive of managing upper respiratory tract infections without antibiotics" 1314:"Association of Broad- vs Narrow-Spectrum Antibiotics With Treatment Failure, Adverse Events, and Quality of Life in Children With Acute Respiratory Tract Infections" 1365:"Effectiveness of N95 respirators versus surgical masks in protecting health care workers from acute respiratory infection: a systematic review and meta-analysis" 1566:
Del-Rio-Navarro BE, Espinosa Rosales F, Flenady V, Sienra-Monge JJ (October 2006). "Immunostimulants for preventing respiratory tract infection in children".
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van Riel D, Munster VJ, de Wit E, Rimmelzwaan GF, Fouchier RA, Osterhaus AD, Kuiken T (April 2006). "H5N1 Virus Attachment to Lower Respiratory Tract".
479:; ideal humidity for indoor spaces is between 40 and 60%. Therefore, relative humidity in this range can help lessen the risk of aerosol transmission. 231:
Lower respiratory tract infections (LRIs) are generally more severe than upper respiratory infections. LRIs are the leading cause of death among all
985: 1517:"Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data" 1468:"Antibiotics for preventing suppurative complications from undifferentiated acute respiratory infections in children under five years of age" 1772: 429: 1234: 1221: 1139: 1131: 1111: 1103: 1068: 49: 1419:"Topical antibiotic prophylaxis to reduce respiratory tract infections and mortality in adults receiving mechanical ventilation" 1292: 1260: 1171: 1225: 762: 499:
and temperature. Temperate climate winters have lower relative humidity, which is known to increase the transmission of
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Of the viruses that cause respiratory infections in humans, most have seasonal variation in prevalence. Influenza,
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that need a more severe treatment course; antibiotic use is not recommended for common bacterial infections as the
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affects both the upper and lower respiratory tracts, but more dangerous strains such as the highly pernicious
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Zavorsky GS (March 2013). "The rise in carboxyhemoglobin from repeated pulmonary diffusing capacity tests".
1762: 1080: 535: 1607:"Exercise versus no exercise for the occurrence, severity, and duration of acute respiratory infections" 454:(ICU) have a higher risk of acquiring an RTI. A combination of topical and systematic antibiotics taken 737: 340: 1515:
Martineau AR, Jolliffe DA, Hooper RL, Greenberg L, Aloia JF, Bergman P, et al. (February 2017).
938:"Rapid viral diagnosis for acute febrile respiratory illness in children in the Emergency Department" 771: 458:
can prevent infection and improve adults' overall mortality in the ICU for adult patients receiving
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Gerber JS, Ross RK, Bryan M, Localio AR, Szymczak JE, Wasserman R, et al. (December 2017).
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risk of further complications if left untreated. Unnecessary use of antibiotics could increase
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will resolve such infections. This medicine does not effectively treat a viral infection like
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Eccles MP, Grimshaw JM, Johnston M, Steen N, Pitts NB, Thomas R, et al. (August 2007).
1685: 1668: 1135: 1024: 1013:"Detecting bacterial lung infections: in vivo evaluation of in vitro volatile fingerprints" 451: 376: 357: 1284: 8: 785: 559:
Thapa S, Gokhale S, Sharma AL, Sapkota LB, Ansari S, Gautam R, et al. (2017-10-01).
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Minozzi S, Pifferi S, Brazzi L, Pecoraro V, Montrucchio G, D'Amico R (January 2021).
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Smith JD, MacDougall CC, Johnstone J, Copes RA, Schwartz B, Garber GE (May 2016).
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Grande, Antonio Jose; Keogh, Justin; Silva, Valter; Scott, Anna M. (2020-04-04).
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present on Earth can thrive in various environments, including the human body.
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Alves Galvão MG, Rocha Crispino Santos MA, Alves da Cunha AJ (February 2016).
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Antibiotic Use in the United States, 2018 Update: Progress and Opportunities
853: 84:, tend to be far more severe than upper respiratory infections, such as the 1694: 1648: 1583: 1552: 1501: 1452: 1398: 1349: 1054: 971: 909: 861: 698: 671: 652: 596: 155: 31: 1220: 1130: 1102: 539: 531: 455: 392: 171: 163: 143: 139: 85: 1380: 1067: 936:
Doan Q, Enarson P, Kissoon N, Klassen TP, Johnson DW (September 2014).
527: 400: 380: 353: 236: 221: 175: 147: 1727: 1533: 500: 404: 396: 244: 240: 159: 151: 81: 443: 372: 191: 183: 1108:"Antibiotic Use Questions and Answers – What Everyone Should Know" 542:, with the exception of rhinoviruses, tend to peak in the summer. 475:
Viruses that cause RTI are more transmissible at very high or low
611:"Upper respiratory tract: MedlinePlus Medical Encyclopedia Image" 487:
Respiratory infections often have strong seasonal patterns, with
424: 128: 112: 1514: 837: 804:"Book Review – Therapeutic Guidelines: Antibiotics (Version 13)" 72:. An infection of this type usually is further classified as an 492: 274:
Deaths from respiratory infections per million persons in 2012
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or vocal cords; sometimes, it is taken as the tract above the
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Zhu J, Bean HD, Wargo MJ, Leclair LW, Hill JE (March 2013).
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respiratory infections reduces the rates of antibiotic use,
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Beaglehole, Robert; Irwin, Alec; Prentice, Thomson (2004).
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Typical infections of the upper respiratory tract include
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Moriyama M, Hugentobler WJ, Iwasaki A (September 2020).
1193:"Antibiotics — When To Use & Do They Treat Viruses?" 1279: 1247: 1158: 760: 427:, and other intense side effects. A study published in 1311: 538:
have variable peaks depending on the specific strain.
1604: 80:(LRI or LRTI). Lower respiratory infections, such as 1717: 1098: 1096: 197: 96: 1010: 986:"Breath Test Could Sniff Out Infections in Minutes" 16:
Infectious disease affecting nose, throat and lungs
1093: 1754: 764:The World Health Report 2004 - Changing History 693:. Treasure Island (FL): StatPearls Publishing. 442:Despite the superior filtration capability of 1669:"Seasonality of Respiratory Viral Infections" 795: 251:tend to bind to receptors deep in the lungs. 685:Thomas, Micah; Bomar, Paul A. (2023-06-26). 1611:The Cochrane Database of Systematic Reviews 1568:The Cochrane Database of Systematic Reviews 1472:The Cochrane Database of Systematic Reviews 1423:The Cochrane Database of Systematic Reviews 942:The Cochrane Database of Systematic Reviews 931: 929: 927: 684: 534:) occur mostly in the spring and fall, and 1235:US Department of Health and Human Services 1222:Centers for Disease Control and Prevention 1140:US Department of Health and Human Services 1132:Centers for Disease Control and Prevention 1112:US Department of Health and Human Services 1104:Centers for Disease Control and Prevention 30: 1684: 1638: 1542: 1532: 1491: 1442: 1388: 1339: 1044: 961: 890:Respiratory Physiology & Neurobiology 822: 661: 651: 627: 586: 576: 1069:National Human Genome Research Institute 924: 887: 269: 253: 1662: 1660: 1658: 754: 1755: 1686:10.1146/annurev-virology-012420-022445 1293:Department of Health & Social Care 1261:Department of Health & Social Care 1172:Department of Health & Social Care 119:. This part of the tract includes the 1412: 1410: 1408: 883: 881: 879: 801: 1655: 1190: 687:"Upper Respiratory Tract Infection" 462:for at least 48 hours, and topical 444:N95 filtering facepiece respirators 111:is considered the airway above the 13: 1773:Viral respiratory tract infections 1405: 876: 516:are more prevalent in the winter. 14: 1784: 1713: 383:are a medicine designed to treat 360:. The relative risk reduction of 204:Lower respiratory tract infection 198:Lower respiratory tract infection 103:Upper respiratory tract infection 97:Upper respiratory tract infection 78:lower respiratory tract infection 74:upper respiratory tract infection 1136:"Treatment for Common Illnesses" 1598: 1559: 1508: 1459: 1356: 1305: 1273: 1241: 1214: 1184: 1152: 1124: 1061: 1004: 978: 482: 235:. The two most common LRIs are 166:. Symptoms of URIs can include 1623:10.1002/14651858.CD010596.pub3 1576:10.1002/14651858.CD004974.pub2 1484:10.1002/14651858.CD007880.pub3 1435:10.1002/14651858.CD000022.pub4 954:10.1002/14651858.CD006452.pub4 831: 730: 705: 678: 603: 552: 1: 802:Dwyer, Sophie (1 June 2007). 565:BMJ Open Respiratory Research 545: 437: 68:involving the lower or upper 1285:"Antibiotics – Side Effects" 1081:National Institute of Health 1037:10.1088/1752-7155/7/1/016003 824:10.18773/austprescr.2007.042 367: 265: 58:Respiratory tract infections 7: 578:10.1136/bmjresp-2017-000203 536:human parainfluenza viruses 25:Respiratory tract infection 10: 1789: 1017:Journal of Breath Research 902:10.1016/j.resp.2013.01.001 341:Pulmonary Function Testing 201: 100: 1721: 1673:Annual Review of Virology 772:World Health Organization 491:more affected during the 43: 38: 29: 24: 1253:"Antibiotics – Overview" 1191:Kent, Dan (2019-03-01). 717:www.medicalnewstoday.com 91: 1332:10.1001/jama.2017.18715 1281:National Health Service 1249:National Health Service 1160:National Health Service 854:10.1126/science.1125548 419:infections, affect the 210:lower respiratory tract 190:, facial pressure, and 109:upper respiratory tract 653:10.1186/1748-5908-2-26 640:Implementation Science 509:Human orthopneumovirus 464:antibiotic prophylaxis 460:mechanical ventilation 337: 262: 811:Australian Prescriber 523:Human metapneumovirus 377:unicellular organisms 273: 257: 1768:Respiratory diseases 1164:"Antibiotics – Uses" 791:on December 5, 2004. 738:"Respiratory system" 452:intensive care units 417:antibiotic-resistant 385:bacterial infections 1763:Infectious diseases 1381:10.1503/cmaj.150835 1029:2013JBR.....7a6003Z 990:Scientific American 742:myhealth.alberta.ca 514:human coronaviruses 233:infectious diseases 76:(URI or URTI) or a 66:infectious diseases 39:Conducting passages 1291:. United Kingdom: 1259:. United Kingdom: 1195:. Washington, DC: 1170:. United Kingdom: 774:. pp. 120–4. 526:occur year-round, 489:temperate climates 425:allergic reactions 338: 263: 259:Respiratory system 50:Infectious disease 1750: 1749: 1534:10.1136/bmj.i6583 1326:(23): 2325–2336. 1197:Kaiser Permanente 992:. 11 January 2013 530:(which cause the 497:relative humidity 477:relative humidity 334: 1,210-2,090 117:cricoid cartilage 70:respiratory tract 55: 54: 19:Medical condition 1780: 1719: 1718: 1707: 1706: 1688: 1664: 1653: 1652: 1642: 1602: 1596: 1595: 1563: 1557: 1556: 1546: 1536: 1512: 1506: 1505: 1495: 1463: 1457: 1456: 1446: 1414: 1403: 1402: 1392: 1360: 1354: 1353: 1343: 1309: 1303: 1302: 1300: 1299: 1277: 1271: 1270: 1268: 1267: 1245: 1239: 1238: 1232: 1218: 1212: 1211: 1209: 1208: 1199:. 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Retrieved 614: 605: 568: 564: 554: 528:rhinoviruses 521: 507: 505: 486: 483:Epidemiology 474: 449: 441: 428: 413: 393:sore throats 371: 339: 280: 24-120 230: 216:(windpipe), 207: 186:, low-grade 156:otitis media 137: 106: 61: 57: 56: 532:common cold 512:(RSV), and 381:Antibiotics 362:chest x-ray 222:bronchioles 172:sore throat 164:common cold 144:pharyngitis 140:tonsillitis 86:common cold 1757:Categories 1298:2024-01-08 1266:2024-01-08 1207:2020-11-19 1177:2024-01-08 1145:2024-01-08 1117:2024-01-08 1086:2024-01-08 1077:Genome.gov 1073:"Bacteria" 996:5 February 747:2024-02-15 723:2022-07-01 691:StatPearls 620:2022-07-01 546:References 450:Adults in 438:Prevention 401:bronchitis 237:bronchitis 224:, and the 176:runny nose 158:, certain 148:laryngitis 1703:214601321 1631:1469-493X 1527:: i6583. 817:(3): 73. 501:influenza 423:, create 405:sinusitis 397:influenza 368:Treatment 266:Diagnosis 245:Influenza 241:pneumonia 160:influenza 152:sinusitis 82:pneumonia 45:Specialty 1695:32196426 1649:32246780 1584:17054227 1553:28202713 1502:26923064 1493:10329867 1453:33481250 1399:26952529 1350:29260224 1224:(2019). 1055:23307645 972:25222468 910:23333819 870:33294327 862:16556800 699:30422556 672:17683558 597:29071076 373:Bacteria 192:sneezing 184:headache 1741:D012141 1640:7127736 1592:7024017 1544:5310969 1444:8094382 1390:4868605 1341:5820700 1046:4114336 1025:Bibcode 963:6718218 918:2355039 841:Science 663:2042498 588:5652512 350:febrile 261:anatomy 214:trachea 129:pharynx 125:sinuses 113:glottis 1701:  1693:  1647:  1637:  1629:  1590:  1582:  1551:  1541:  1500:  1490:  1451:  1441:  1397:  1387:  1348:  1338:  1289:nhs.uk 1257:nhs.uk 1168:nhs.uk 1053:  1043:  970:  960:  916:  908:  868:  860:  778:  697:  670:  660:  646:: 26. 595:  585:  493:winter 332:  326:  320:  314:  308:  302:  296:  290:  284:  278:  133:larynx 131:, and 64:) are 1699:S2CID 1588:S2CID 1231:(PDF) 914:S2CID 866:S2CID 807:(PDF) 789:(PDF) 768:(PDF) 356:, or 226:lungs 188:fever 168:cough 92:Types 1736:MeSH 1691:PMID 1645:PMID 1627:ISSN 1615:2020 1580:PMID 1549:PMID 1498:PMID 1476:2016 1449:PMID 1395:PMID 1369:CMAJ 1346:PMID 1319:JAMA 1051:PMID 998:2013 968:PMID 946:2014 906:PMID 858:PMID 776:ISBN 695:PMID 668:PMID 593:PMID 520:and 430:JAMA 375:are 249:H5N1 239:and 208:The 121:nose 107:The 62:RTIs 1681:doi 1635:PMC 1619:doi 1572:doi 1539:PMC 1529:doi 1525:356 1521:BMJ 1488:PMC 1480:doi 1439:PMC 1431:doi 1385:PMC 1377:doi 1373:188 1336:PMC 1328:doi 1324:318 1041:PMC 1033:doi 958:PMC 950:doi 898:doi 894:186 850:doi 846:312 819:doi 658:PMC 648:doi 583:PMC 573:doi 1759:: 1739:: 1697:. 1689:. 1675:. 1671:. 1657:^ 1643:. 1633:. 1625:. 1613:. 1609:. 1586:. 1578:. 1547:. 1537:. 1523:. 1519:. 1496:. 1486:. 1474:. 1470:. 1447:. 1437:. 1425:. 1421:. 1407:^ 1393:. 1383:. 1371:. 1367:. 1344:. 1334:. 1322:. 1316:. 1287:. 1255:. 1166:. 1138:. 1110:. 1095:^ 1079:. 1075:. 1049:. 1039:. 1031:. 1019:. 1015:. 988:. 966:. 956:. 944:. 940:. 926:^ 912:. 904:. 892:. 878:^ 864:. 856:. 844:. 815:30 813:. 809:. 770:. 740:. 715:. 689:. 666:. 656:. 642:. 638:. 613:. 591:. 581:. 567:. 563:. 503:. 411:. 403:, 399:, 395:, 243:. 228:. 220:, 194:. 182:, 178:, 174:, 170:, 154:, 150:, 146:, 142:, 135:. 127:, 123:, 88:. 1728:D 1705:. 1683:: 1677:7 1651:. 1621:: 1594:. 1574:: 1555:. 1531:: 1504:. 1482:: 1455:. 1433:: 1427:1 1401:. 1379:: 1352:. 1330:: 1301:. 1269:. 1237:. 1210:. 1180:. 1148:. 1120:. 1089:. 1057:. 1035:: 1027:: 1021:7 1000:. 974:. 952:: 920:. 900:: 872:. 852:: 827:. 821:: 750:. 726:. 701:. 674:. 650:: 644:2 623:. 599:. 575:: 569:4 60:(

Index


Specialty
Infectious disease
infectious diseases
respiratory tract
upper respiratory tract infection
lower respiratory tract infection
pneumonia
common cold
Upper respiratory tract infection
upper respiratory tract
glottis
cricoid cartilage
nose
sinuses
pharynx
larynx
tonsillitis
pharyngitis
laryngitis
sinusitis
otitis media
influenza
common cold
cough
sore throat
runny nose
nasal congestion
headache
fever

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