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in 1974. He joined Duke
University's faculty in 1976 and has been a Howard Hughes Investigator since 1995. He works primarily on strand-directed mismatch repair. His lab demonstrated how DNA mismatch repair serves as a copyeditor to prevent errors from
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628:"Plenkovic welcomed an American Nobel Prize winner of Croatian origin who is responsible for one of the most important discoveries in medicine history: This was Modrich's first visit to the homeland of his ancestors"
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to
Laurence Modrich and Margaret McTurk. He has a younger brother Dave. His father was a biology teacher and coach for basketball, football and tennis at
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in the late 19th century. His maternal family is of mixed German and Scotch-Irish descent. Modrich married fellow scientist
Vickers Burdett in 1980.
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678:...my wife and I, we visited the village yesterday where my grandparent, grandfather may have been born, Modrići, I believe it is called
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previously proposed the existence of recognition of mismatches. Modrich performed biochemical experiments to study mismatch repair in
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490:"Nobel Prize in Chemistry Awarded to Tomas Lindahl, Paul Modrich and Aziz Sancar for DNA Studies"
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origin. His paternal grandfather, of
Croatian descent, is probably from the small village of
310:
1426:
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840:
329:, and grandmother of Montenegrin descent, both immigrated to the United States from coastal
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834:
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524:"THE NOBEL PRIZE IN CHEMISTRY 2015 – DNA repair – providing chemical stability for life"
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2016:
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2016: Arthur
Kornberg and Paul Berg Lifetime Achievement Award in Biomedical Sciences
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2020:
1968:
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Proceedings of the
National Academy of Sciences of the United States of America
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385:. They later searched for proteins associated with mismatch repair in humans.
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747:"Escherichia coli mutS-encoded protein binds to mismatched DNA base pairs"
694:[Nobel laureate Modrich for tportal: My grandfather was a Croat].
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Paul L. Modrich, Nobel
Laureate in chemistry in Stockholm December 2015
43:
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1645:
1271:
368:
Modrich became an assistant professor at the chemistry department of
592:"Childhood in Raton helped shape life of Nobel winner in chemistry"
330:
180:
412:
Robert J. and Claire
Pasarow Foundation Medical Research Award
352:
in 1973. He continued his research as a postdoc in the lab of
187:
Structure, mechanism and biological role of E. coli DNA ligase
870:
326:
2577:
Members of the United States
National Academy of Sciences
374:
94:
630:. International Society for Applied Biological Sciences
689:
2582:
Fellows of the
American Academy of Arts and Sciences
721:"For Paul Modrich, frenzy and failures yield truths"
692:"Nobelovac Modrich za tportal: Djed mi je bio Hrvat"
467:"Paul Modrich Awarded 2015 Nobel Prize in Chemistry"
650:"Večer S Nobelovcima – Nobel Spirit 2 (ISABS 2019)"
109:
Clarification of cellular resistance to carcinogens
27:American biochemist and Nobel Laureate (born 1946)
2508:
393:Honors and awards received by Modrich include:
2270:
2256:
856:
2592:Members of the National Academy of Medicine
690:Nenad Jarić Dauenhauer (October 26, 2015).
275:
2263:
2249:
863:
849:
833:
557:
555:
553:
551:
549:
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305:where he graduated in 1964. Modrich is of
121:Member of the National Academy of Sciences
780:
770:
744:
589:
279:
2547:American people of Scotch-Irish descent
546:
14:
2537:American people of Montenegrin descent
2509:
807:. Stanford Medicine Alumni Association
683:
668:from the original on December 15, 2021
461:
459:
297:Modrich was born on June 13, 1946, in
2244:
844:
521:
488:Broad, William J. (October 7, 2015).
487:
436:American Academy of Arts and Sciences
342:Massachusetts Institute of Technology
585:
583:
388:
236:(born June 13, 1946) is an American
2567:Howard Hughes Medical Investigators
2532:American people of Croatian descent
590:Simonich, Milan (October 8, 2015).
456:
24:
2350:Tunisian National Dialogue Quartet
370:University of California, Berkeley
256:. He is known for his research on
171:University of California, Berkeley
25:
2603:
2542:American people of German descent
823:
580:
1093:
745:Su, SS; Modrich, P (July 1986).
399:Pfizer Award in Enzyme Chemistry
42:
797:
738:
713:
293:Paul Modrich presenting himself
254:Howard Hughes Medical Institute
166:Howard Hughes Medical Institute
2427:(United Kingdom/United States)
642:
620:
609:
481:
427:2015: Nobel Prize in Chemistry
13:
1:
2587:People from Raton, New Mexico
563:"Paul Modrich – Biographical"
469:. HHMI. HHMI. October 7, 2015
449:
2522:Nobel laureates in Chemistry
444:National Academy of Sciences
440:National Academy of Medicine
7:
805:"Paul L. Modrich (PhD '73)"
434:Modrich is a fellow of the
363:
344:in 1968 and subsequently a
10:
2608:
2552:Stanford University alumni
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2415:
2384:
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2335:
2311:
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1899:
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522:Staff (October 7, 2015).
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113:
105:
90:
82:
53:
41:
34:
2557:American Nobel laureates
2017:Venkatraman Ramakrishnan
1296:Wendell Meredith Stanley
876:Nobel Prize in Chemistry
658:Hrvatska radiotelevizija
360:for a year (1973–1974).
276:Early life and education
262:Nobel Prize in Chemistry
252:and Investigator at the
127:Nobel Prize in Chemistry
2527:Duke University faculty
2396:(Ireland/United States)
2292:(Sweden/United Kingdom)
772:10.1073/pnas.83.14.5057
422:American Cancer Society
417:2000 Feodor Lynen Medal
260:. Modrich received the
242:James B. Duke Professor
225:/paul-l-modrich-primary
2440:Nobel Prize recipients
2386:Physiology or Medicine
2304:(Turkey/United States)
2181:Emmanuelle Charpentier
2169:M. Stanley Whittingham
1140:Hans von Euler-Chelpin
358:Harvard Medical School
294:
1551:Christian B. Anfinsen
1191:Frédéric Joliot-Curie
405:Charles S. Mott Prize
403:1996: General Motors
354:Charles C. Richardson
292:
234:Paul Lawrence Modrich
58:Paul Lawrence Modrich
2562:American biochemists
2213:Karl Barry Sharpless
1710:Dudley R. Herschbach
1535:Luis Federico Leloir
438:and a member of the
2394:William C. Campbell
2326:Svetlana Alexievich
2205:Carolyn R. Bertozzi
2117:Jean-Pierre Sauvage
1854:Jens Christian Skou
1822:F. Sherwood Rowland
1734:Charles J. Pedersen
1698:Herbert A. Hauptman
1391:Vincent du Vigneaud
1008:Richard Willstätter
892:Jacobus van 't Hoff
763:1986PNAS...83.5057S
725:News & Observer
414:for cancer research
350:Stanford University
336:Modrich obtained a
264:2015, jointly with
258:DNA mismatch repair
148:DNA mismatch repair
99:Stanford University
2375:Arthur B. McDonald
2165:John B. Goodenough
2093:William E. Moerner
1973:Richard R. Schrock
1945:Roderick MacKinnon
1917:K. Barry Sharpless
1742:Johann Deisenhofer
1571:Geoffrey Wilkinson
1567:Ernst Otto Fischer
1491:Robert S. Mulliken
1427:Jaroslav HeyrovskĂ˝
1375:Hermann Staudinger
1195:Irène Joliot-Curie
832:on Nobelprize.org
700:T-Hrvatski Telekom
616:Last name: McTurk
567:www.nobelprize.org
494:The New York Times
407:in Cancer Research
295:
2504:
2503:
2417:Economic Sciences
2238:
2237:
2221:Moungi G. Bawendi
2141:Richard Henderson
1985:Roger D. Kornberg
1953:Aaron Ciechanover
1786:Rudolph A. Marcus
1690:Robert Merrifield
1626:Peter D. Mitchell
1399:Cyril Hinshelwood
1160:Friedrich Bergius
1084:Richard Zsigmondy
1000:Theodore Richards
948:Ernest Rutherford
389:Honors and awards
319:Scottish (Gaelic)
303:Raton High School
299:Raton, New Mexico
290:
231:
230:
138:Scientific career
75:Raton, New Mexico
16:(Redirected from
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2265:
2258:
2251:
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2231:
2229:Alexei I. Ekimov
2215:
2209:Morten P. Meldal
2199:
2187:
2175:
2159:
2143:
2133:Jacques Dubochet
2127:
2111:
2095:
2079:
2063:
2057:Robert Lefkowitz
2051:
2043:
2027:
2021:Thomas A. Steitz
2011:
1995:
1987:
1979:
1969:Robert H. Grubbs
1963:
1947:
1935:
1919:
1892:
1890:Hideki Shirakawa
1876:
1868:
1856:
1840:
1824:
1808:
1800:
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1778:Richard R. Ernst
1772:
1764:
1752:
1736:
1720:
1704:
1692:
1684:
1676:
1668:
1656:
1654:Frederick Sanger
1640:
1634:Herbert C. Brown
1628:
1620:
1612:
1610:William Lipscomb
1593:
1581:
1573:
1561:
1545:
1543:Gerhard Herzberg
1537:
1529:
1517:
1509:
1493:
1485:
1477:
1469:
1457:
1445:
1437:
1429:
1421:
1419:Frederick Sanger
1413:
1405:
1403:Nikolay Semyonov
1393:
1385:
1377:
1369:
1357:
1355:Glenn T. Seaborg
1334:
1322:
1314:
1306:
1298:
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1280:Artturi Virtanen
1274:
1266:
1264:George de Hevesy
1258:
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1225:
1217:
1205:
1197:
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1177:
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1130:
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1120:Heinrich Wieland
1114:
1112:Theodor Svedberg
1097:
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924:Adolf von Baeyer
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908:Svante Arrhenius
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379:Matthew Meselson
340:degree from the
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199:Doctoral advisor
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2298:(United States)
2296:Paul L. Modrich
2276:
2269:
2239:
2234:
2218:
2202:
2193:David MacMillan
2190:
2185:Jennifer Doudna
2178:
2162:
2146:
2130:
2121:Fraser Stoddart
2114:
2105:Paul L. Modrich
2098:
2082:
2066:
2054:
2046:
2041:Ei-ichi Negishi
2033:Richard F. Heck
2030:
2014:
2001:Osamu Shimomura
1998:
1990:
1982:
1966:
1950:
1938:
1922:
1909:William Knowles
1906:
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1886:Alan MacDiarmid
1879:
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1827:
1814:Paul J. Crutzen
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1730:Jean-Marie Lehn
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1483:Robert Woodward
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1285:
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1235:Leopold RuĹľiÄŤka
1231:Adolf Butenandt
1228:
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1168:Irving Langmuir
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1053:Frederick Soddy
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980:Victor Grignard
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956:Wilhelm Ostwald
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889:
878:
869:
830:Paul L. Modrich
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798:
757:(14): 5057–61.
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662:Dragan Primorac
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250:Duke University
215:
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175:
161:Duke University
132:
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91:Alma mater
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72:
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2369:Takaaki Kajita
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2200:
2188:
2176:
2160:
2153:Gregory Winter
2149:Frances Arnold
2144:
2128:
2112:
2096:
2080:
2073:Michael Levitt
2069:Martin Karplus
2064:
2052:
2044:
2028:
2012:
2009:Roger Y. Tsien
2005:Martin Chalfie
1996:
1988:
1980:
1964:
1948:
1936:
1920:
1903:
1901:
1897:
1896:
1894:
1893:
1882:Alan J. Heeger
1877:
1869:
1857:
1850:John E. Walker
1841:
1825:
1809:
1801:
1789:
1781:
1773:
1765:
1753:
1750:Hartmut Michel
1737:
1726:Donald J. Cram
1721:
1705:
1693:
1685:
1677:
1669:
1666:Roald Hoffmann
1657:
1650:Walter Gilbert
1641:
1629:
1621:
1618:Ilya Prigogine
1613:
1604:
1602:
1598:
1597:
1595:
1594:
1587:John Cornforth
1582:
1574:
1562:
1555:Stanford Moore
1546:
1538:
1530:
1518:
1510:
1503:Ronald Norrish
1494:
1486:
1478:
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1458:
1446:
1438:
1430:
1422:
1414:
1411:Alexander Todd
1406:
1394:
1386:
1378:
1370:
1358:
1351:Edwin McMillan
1345:
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1339:
1338:
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1315:
1307:
1299:
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1238:
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1218:
1211:Norman Haworth
1206:
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1045:Walther Nernst
1040:
1033:
1025:
1018:
1011:
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987:
975:
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959:
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940:Eduard Buchner
935:
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919:
916:William Ramsay
911:
903:
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1874:Ahmed Zewail
1834:Harold Kroto
1818:Mario Molina
1746:Robert Huber
1718:John Polanyi
1702:Jerome Karle
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1515:Lars Onsager
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2273:Nobel Prize
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2109:Aziz Sancar
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2085:Eric Betzig
1862:Walter Kohn
1830:Robert Curl
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1714:Yuan T. Lee
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1183:Harold Urey
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1030:Fritz Haber
972:Marie Curie
634:December 5,
532:Nobel Prize
311:Montenegrin
266:Aziz Sancar
83:Nationality
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1961:Irwin Rose
1941:Peter Agre
1866:John Pople
1674:Aaron Klug
1579:Paul Flory
1527:Odd Hassel
1451:Max Perutz
1332:Kurt Alder
1328:Otto Diels
1156:Carl Bosch
730:October 9,
696:tportal.hr
601:October 9,
450:References
238:biochemist
64:1946-06-13
2406:Tu Youyou
2352:(Tunisia)
2328:(Belarus)
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1103:1926–1950
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872:Laureates
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2377:(Canada)
672:June 19,
666:Archived
442:and the
364:Research
307:Croatian
219:.biochem
86:American
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2402:(Japan)
2371:(Japan)
2361:Physics
874:of the
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759:Bibcode
654:YouTube
383:E. coli
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144:Fields
129:(2015)
123:(1993)
114:Awards
77:, U.S.
2471:2015
2337:Peace
2271:2015
527:(PDF)
346:Ph.D.
327:Zadar
325:near
221:.duke
101:(PhD)
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813:2018
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732:2016
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475:2015
338:B.S.
317:and
268:and
223:.edu
54:Born
777:PMC
767:doi
375:DNA
356:at
248:at
244:of
217:www
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