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Michael Berridge

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Surprisingly, he found that serotonin and cyclic AMP produced opposite effect to ion movement. While the former reduced the transepithelial potential difference closer to zero, the latter caused an even more negative difference. This suggested cyclic AMP caused positively-charged ions to move across
2412: 480:. He first joined as a senior scientific officer, and was promoted to principal scientific officer in 1972. He became a senior principal scientific officer at the Unit of Insect Neurophysiology and Pharmacology, also at the University of Cambridge, in 1978. 487:
as the Deputy Chief Scientific Officer of the Laboratory of Molecular Signalling, before serving as the Head of Signalling in 1996 until retiring in 2003. After retirement, Berridge was appointed as Babraham's first emeritus Babraham Fellow.
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activation and the release of intracellular Ca from storage. He was inspired by a review article by Robert H. Michell in 1975, which proposed receptor activation caused the breakdown of
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secretion. The idea of second messenger was new at the time, and his finding supported cyclic AMP as a second messenger of serotonin.
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at Cambridge. He and Rasmussen worked together and found serotonin triggered the release of Ca from a storage inside the
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Honorary foreign member of the Royal Academy of Medicine of Belgium (Académie royale de médecine de Belgique) (1991)
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and join the new Unit of Invertebrate Chemistry and Physiology that he was setting up in the Department of
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The physiology of excretion in the cotton stainer, Dysdercus fasciatus Signoret (Hemiptera, Pyrrhocoridae)
4045: 3843: 2731: 2266: 1578: 1522: 1088: 839: 710: 268: 36: 3194: 3178: 1626: 662: 534: 492: 1462:"Role of Calcium and Adenosine-3′:5′-Cyclic Monophosphate in Controlling Fly Salivary Gland Secretion" 4313: 2296: 1011: 4223: 4009: 3676: 3557: 3013: 2749: 2240: 1922: 876: 736: 1234: 4205: 3991: 3431: 3272: 829: 689: 561: 527: 473: 442: 394: 297: 208: 131: 2071:. Royal Academy of Medicine of Belgium (Académie royale de médecine de Belgique). Archived from 1041: 3884: 3742: 2859: 2557: 2496: 2210: 802: 670: 438: 352: 348: 293: 200: 127: 97: 3962: 3135: 1102: 1083: 818: 681: 623: 458: 446: 1136: 4268: 4263: 4039: 3154: 2711: 2613: 2573: 2567: 2524: 1760: 1695: 1475: 1352: 1338: 872: 845: 627: 611:, one of the first researchers to recognise the role of Ca as a second messenger, was on a 564:, and conducted experiments to study how serotonin and cyclic AMP affected the movement of 422: 402: 390: 242: 110: 2464: 1866: 1264: 8: 3938: 3807: 3640: 3497: 3435: 3208: 3105: 2842: 2668: 2386: 1952: 1635: 1290: 1260: 970: 936: 883: 790: 786: 658:
to blow fly salivary glands to inhibit the conversion of inositol phosphate to inositol.
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Proceedings of the National Academy of Sciences of the United States of America
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near Cambridge, Berridge found that phosphatidylinositol was hydrolysed into
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to allowing Ca influx into cells. He hypothesised phosphatidylinositol was
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Berridge, Michael J.; Bootman, Martin D.; Roderick, H. Llewelyn (2003).
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released Ca from the intracellular storage, which he identified as the
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Recipients of the Albert Lasker Award for Basic Medical Research
1042:"Sir Michael John Berridge. 22 October 1938 — 13 February 2020" 554: 219: 2239:. Vol. CXXIX, no. 6. 4 November 1998. Archived from 1680:
Streb, H.; Irvine, R. F.; Berridge, M. J.; Schulz, I. (1983).
1629:; Downes, C. Peter; Heslop, John P.; Irvine, Robin F. (1983). 537:, who had also worked at Case Western Reserve. Working on the 1584:
Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes
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was named in his honour and established with his endowment.
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teacher convinced him and his parents that he should pursue
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Fellows of the Academy of Medical Sciences (United Kingdom)
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in electric potential across the epithelium since ions are
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of the University of Cambridge from 1972 until his death.
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Berridge then wanted to identify the connection between
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He continued studying cyclic AMP after returning to the
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Dr H. P. Heineken Prize for Biochemistry and Biophysics
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Dr H. P. Heineken Prize for Biochemistry and Biophysics
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Members of the European Molecular Biology Organization
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Foreign associates of the National Academy of Sciences
650:(DAG), and the former was eventually broken down into 545:
species, Berridge showed cyclic AMP produced the same
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Fellows of the American Academy of Arts and Sciences
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Biographical Memoirs of Fellows of the Royal Society
401:, where Wigglesworth was a fellow, and obtained his 280:(22 October 1938 - 13 February 2020) was a British 596:to the inside of the salivary gland (known as the 2009:"1989 Albert Lasker Basic Medical Research Award" 1401:Berridge, Michael J.; Prince, William T. (1972). 4255: 4274:Alumni of Gonville and Caius College, Cambridge 1231:"The Prize in Life Science & Medicine 2005" 2219:(1st supplement). 30 December 1997. p. 1. 1400: 762:Albert Lasker Award for Basic Medical Research 158:Albert Lasker Award for Basic Medical Research 4384:Members of the American Philosophical Society 3565: 2921: 2480: 1336: 676:and DAG. Later the same year, he confirmed IP 1284: 1282: 98:University College of Rhodesia and Nyasaland 960: 958: 315: 3572: 3558: 2928: 2914: 2487: 2473: 1456:Prince, William T.; Berridge, Michael J.; 999: 997: 995: 993: 725:King Faisal International Prize in Science 498:Berridge maintained an online textbook on 142:King Faisal International Prize in Science 4339:Rhodesian emigrants to the United Kingdom 2185:"Massry Prize Winners ( 1996 – Present )" 1743: 1656: 1576: 1497: 1487: 1420: 1279: 1123: 1121: 1101: 1084:"Unlocking the secrets of cell signaling" 1077: 1075: 1073: 1071: 1069: 1057: 2935: 2209: 1520: 1288: 1103:10.1146/annurev.physiol.67.040103.152647 1081: 1039: 955: 19:For the New Zealand cell biologist, see 4319:Fellows of the Royal Society of Biology 2043:European Molecular Biology Organization 990: 890:Shaw Prize in Life Science and Medicine 787:Ciba-Drew Award for Biomedical Research 772:European Molecular Biology Organization 170:Shaw Prize in Life Science and Medicine 4256: 1337:Berridge, M. J.; Patel, N. G. (1968). 1225: 1223: 1198:"In tribute: Sir Michael Berridge FRS" 1162: 1160: 1158: 1156: 1154: 1118: 1066: 911:The Sir Michael Berridge Prize at the 425:, Berridge's plan was thwarted by the 4304:Fellows of Trinity College, Cambridge 3553: 2909: 2468: 2357:American Academy of Arts and Sciences 1809:Nature Reviews Molecular Cell Biology 863:American Academy of Arts and Sciences 861:International Honorary Member of the 703: 2445:. Babraham Institute. Archived from 1528:Molecular and Cellular Endocrinology 692:in its own right and could activate 349:University of Rhodesia and Nyasaland 4344:Rhodesian people of British descent 3579: 1220: 1151: 1129:"Autobiography of Michael Berridge" 743:Canada Gairdner International Award 696:, marked the start of the field of 665:, who was studying inositol at the 433:instead, joining the Department of 347:, and he entered the newly founded 292:, in particular the discovery that 154:Canada Gairdner International Award 16:British physiologist and biochemist 13: 2263:"Sir Michael Berridge FRS FMedSci" 2161:. 10 December 2018. Archived from 2095:"Award winners : Royal Medal" 1204:. 13 February 2020. Archived from 1014:. 21 November 2017. Archived from 974:. 23 February 2020. Archived from 472:invited Berridge to return to the 397:. Berridge became a member at the 14: 4395: 413:Initially intending to return to 4369:Wolf Prize in Medicine laureates 2443:"The Sir Michael Berridge Prize" 1521:Berridge, Michael John. (1981). 731:Louis-Jeantet Prize for Medicine 465:of the same university in 1967. 445:. A year later, he moved to the 146:Louis-Jeantet Prize for Medicine 2435: 2405: 2375: 2345: 2315: 2285: 2255: 2223: 2203: 2177: 2147: 2117: 2087: 2061: 2031: 2001: 1971: 1941: 1911: 1889:"Professor Michael J. Berridge" 1881: 1851: 1795: 1737: 1673: 1618: 1570: 1514: 1449: 1408:Journal of Experimental Biology 1394: 1330: 1249: 1005:"Prof. Dr. Michael J. Berridge" 904:British Pharmacological Society 524:Case Western Reserve University 451:Case Western Reserve University 288:. He was known for his work on 205:Case Western Reserve University 2417:American Philosophical Society 1925:. October 2017. Archived from 1291:"Interview with Mike Berridge" 1190: 1033: 925: 897:American Philosophical Society 576:across the epithelium through 1: 4364:Winners of the Heineken Prize 4354:University of Zimbabwe alumni 2359:. 31 May 2023. Archived from 2236:Cambridge University Reporter 1082:Berridge, Michael J. (2005). 918: 684:. This report, together with 491:Berridge was a fellow of the 483:In 1990, Berridge joined the 4374:Members of Academia Europaea 4329:People from Kadoma, Zimbabwe 4299:Fellows of the Royal Society 2327:National Academy of Sciences 2231:"Gonville and Caius College" 1919:"Professor Michael BERRIDGE" 1597:10.1016/0304-4157(75)90017-9 1541:10.1016/0303-7207(81)90119-2 1365:10.1126/science.162.3852.462 1233:. Shaw Prize. Archived from 856:National Academy of Sciences 688:'s discovery that DAG was a 7: 3588:Biochemistry and Biophysics 2267:Academy of Medical Sciences 1577:Robert H., Michell (1975). 1168:"Sir Michael John Berridge" 1089:Annual Review of Physiology 840:Academy of Medical Sciences 572:controlled the movement of 518:Berridge had been studying 513: 10: 4400: 826:Gonville and Caius College 663:Rex Malcolm Chaplin Dawson 553:, dramatically increasing 535:Earl Wilbur Sutherland Jr. 399:Gonville and Caius College 18: 4138: 4079: 3972: 3865: 3752: 3587: 3364: 3145: 2944: 2852: 2769: 2700: 2633: 2542: 2503: 2413:"Sir Michael J. Berridge" 2297:Ernst Schering Foundation 2125:"Sir Michael J. Berridge" 1257:"Cell Signalling Biology" 1040:Petersen, Ole H. (2024). 1012:Ernst Schering Foundation 408: 265:Sir Michael John Berridge 258: 248: 236: 218: 196: 182: 175: 137: 117: 93: 81: 52: 30: 1923:Louis-Jeantet Foundation 877:Royal Society of Biology 737:William Bate Hardy Prize 592:the epithelium from the 580:. Berridge measured the 370:He became interested in 316:Early life and education 300:, linking events at the 4324:Massry Prize recipients 3432:Demetrios Christodoulou 3273:Everett Peter Greenberg 2353:"Michael John Berridge" 1289:Berridge, Mike (2005). 902:Honorary Fellow of the 882:Honorary Member of the 830:University of Cambridge 824:Honorary Fellow of the 630:, which in turn opened 562:University of Cambridge 474:University of Cambridge 395:University of Cambridge 374:after helping with his 209:University of Cambridge 4359:White Rhodesian people 3885:BirdLife International 3866:Environmental Sciences 2874:Lynne Elizabeth Maquat 2860:Emmanuelle Charpentier 2497:Wolf Prize in Medicine 1979:"Sir Michael Berridge" 1625:Berridge, Michael J.; 1059:10.1098/rsbm.2023.0047 803:Wolf Prize in Medicine 439:University of Virginia 353:University of Zimbabwe 294:inositol trisphosphate 201:University of Virginia 128:inositol trisphosphate 4284:British physiologists 3136:Shrinivas R. Kulkarni 2323:"Michael J. Berridge" 2293:"Michael J. Berridge" 2155:"Michael J. Berridge" 2039:"Michael J. Berridge" 1949:"Michael J. Berridge" 1489:10.1073/pnas.69.3.553 682:endoplasmic reticulum 624:cell surface receptor 461:at the Department of 459:Bodil Schmidt-Nielsen 447:Developmental Biology 429:. He migrated to the 320:Berridge was born in 57:Michael John Berridge 3195:Keith H. S. Campbell 3155:Stanley Norman Cohen 2712:Alexander Varshavsky 2614:Elizabeth F. Neufeld 2574:Jean-Pierre Changeux 2568:Stanley Norman Cohen 1422:10.1242/jeb.56.1.139 873:Institute of Biology 852:International Member 846:Ernst Schering Prize 628:phosphatidylinositol 391:Vincent Wigglesworth 304:with the release of 243:Vincent Wigglesworth 32:Sir Michael Berridge 4349:Royal Medal winners 4279:British biochemists 3498:Alexander Beilinson 3436:Richard S. Hamilton 3106:Chryssa Kouveliotou 2843:Jeffrey M. Friedman 2669:Stanley B. Prusiner 2449:on 11 November 2023 2393:on 20 November 2023 2387:Biochemical Society 2363:on 20 November 2023 2333:on 20 November 2023 2303:on 14 November 2023 2273:on 20 November 2023 2243:on 14 November 2023 2191:on 14 November 2023 2165:on 14 November 2023 2135:on 14 November 2023 2105:on 20 November 2023 2049:on 17 November 2023 1989:on 17 November 2023 1959:on 14 November 2023 1953:Gairdner Foundation 1929:on 14 November 2023 1899:on 14 November 2023 1869:on 17 November 2023 1765:1984Natur.308..693N 1745:Nishizuka, Yasutomi 1700:1983Natur.306...67S 1636:Biochemical Journal 1480:1972PNAS...69..553P 1437:on 28 November 2023 1357:1968Sci...162..462B 1267:on 19 December 2023 1261:Biochemical Society 1237:on 11 November 2023 1208:on 11 November 2023 978:on 27 February 2020 937:New College, Oxford 884:Biochemical Society 791:Novartis-Drew Award 603:Berridge suspected 594:extracellular fluid 508:Biochemical Society 443:postdoctoral fellow 3508:Jean-Michel Bismut 3235:Franz-Ulrich Hartl 3058:William J. Borucki 2821:Jeffrey V. Ravetch 2742:Alexander Levitzki 2663:Yasutomi Nishizuka 2564:Barbara McClintock 2423:on 2 November 2023 2383:"Honorary Members" 2216:The London Gazette 2075:on 29 January 2023 2069:"BERRIDGE Michael" 2019:on 2 November 2023 1859:"Michael Berridge" 1309:10.1002/bies.20186 1202:Babraham Institute 1178:on 8 November 2023 1139:on 7 November 2023 1021:on 3 November 2023 943:on 6 November 2023 913:Babraham Institute 704:Awards and honours 686:Yasutomi Nishizuka 667:Babraham Institute 644:inositol phosphate 485:Babraham Institute 455:research associate 427:Rhodesian Bush War 385:, and went to the 345:tertiary education 213:Babraham Institute 107:University College 4251: 4250: 4080:Cognitive Science 3547: 3546: 3528:Vladimir Drinfeld 3374:Shiing-Shen Chern 3331:Paul A. Negulescu 3239:Arthur L. Horwich 3112:Lennart Lindegren 3044:Daniel Eisenstein 2903: 2902: 2884:Daniel J. Drucker 2746:Anthony R. Hunter 2718:Ralph L. Brinster 2600:Pedro Cuatrecasas 2588:Donald F. Steiner 2578:Solomon H. Snyder 2533:Oleh Hornykiewicz 2495:Laureates of the 1983:Academia Europaea 1893:King Faisal Prize 1759:(5961): 693–698. 1649:10.1042/bj2120473 1627:Dawson, Rex M. C. 1458:Rasmussen, Howard 1351:(3852): 462–463. 1172:Academia Europaea 750:Academia Europaea 698:calcium signaling 415:Southern Rhodesia 372:insect physiology 330:Southern Rhodesia 262: 261: 177:Scientific career 75:Southern Rhodesia 4391: 4314:Knights Bachelor 3945:Sinninghe DamstĂ© 3574: 3567: 3560: 3551: 3550: 3492:Michel Talagrand 3442:Maxim Kontsevich 3396:Robert Langlands 3335:Michael J. Welsh 3299:Mary-Claire King 3253:Michael W. Young 3225:Ruslan Medzhitov 3209:Jeffrey Friedman 3185:Robert Lefkowitz 3173:Michael Berridge 3130:Maura McLaughlin 3116:Michael Perryman 2930: 2923: 2916: 2907: 2906: 2894:JosĂ©-Alain Sahel 2837:James P. Allison 2827:Lewis C. Cantley 2817:Philippa Marrack 2659:Michael Berridge 2489: 2482: 2475: 2466: 2465: 2459: 2458: 2456: 2454: 2439: 2433: 2432: 2430: 2428: 2419:. 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Archived from 933:"Antony Galione" 929: 694:protein kinase C 690:second messenger 609:Howard Rasmussen 528:second messenger 502:, now hosted by 326:Kadoma, Zimbabwe 308:(Ca) within the 298:second messenger 279: 249:Notable students 238:Doctoral advisor 232: 132:second messenger 88: 85:13 February 2020 66: 64: 47: 28: 27: 4399: 4398: 4394: 4393: 4392: 4390: 4389: 4388: 4254: 4253: 4252: 4247: 4134: 4075: 3968: 3861: 3748: 3583: 3581:Heineken Prizes 3578: 3548: 3543: 3522:Ehud Hrushovski 3486:Luis Caffarelli 3420:Clifford Taubes 3416:Simon Donaldson 3406:Vladimir Arnold 3366: 3360: 3351:Stuart H. Orkin 3311:Gero Miesenböck 3249:Michael Rosbash 3245:Jeffrey C. Hall 3205:Douglas Coleman 3199:Shinya Yamanaka 3147: 3141: 3096:Roger Blandford 3090:Edward C. Stone 3084:Jean-Loup Puget 3052:John A. Peacock 3024:David C. Jewitt 3000:Charles Bennett 2988:Reinhard Genzel 2982:Peter Goldreich 2968:Saul Perlmutter 2940: 2934: 2904: 2899: 2864:Jennifer Doudna 2848: 2799:Nahum Sonenberg 2793:Ronald M. Evans 2787:Rudolf Jaenisch 2783:Shinya Yamanaka 2765: 2732:Robert Weinberg 2726:Oliver Smithies 2696: 2629: 2624:Edward B. Lewis 2558:James L. Gowans 2538: 2519:Jon J. van Rood 2499: 2493: 2463: 2462: 2452: 2450: 2441: 2440: 2436: 2426: 2424: 2411: 2410: 2406: 2396: 2394: 2381: 2380: 2376: 2366: 2364: 2351: 2350: 2346: 2336: 2334: 2321: 2320: 2316: 2306: 2304: 2291: 2290: 2286: 2276: 2274: 2261: 2260: 2256: 2246: 2244: 2229: 2228: 2224: 2208: 2204: 2194: 2192: 2183: 2182: 2178: 2168: 2166: 2159:Wolf Foundation 2153: 2152: 2148: 2138: 2136: 2129:Heineken Prizes 2123: 2122: 2118: 2108: 2106: 2093: 2092: 2088: 2078: 2076: 2067: 2066: 2062: 2052: 2050: 2037: 2036: 2032: 2022: 2020: 2007: 2006: 2002: 1992: 1990: 1977: 1976: 1972: 1962: 1960: 1947: 1946: 1942: 1932: 1930: 1917: 1916: 1912: 1902: 1900: 1887: 1886: 1882: 1872: 1870: 1857: 1856: 1852: 1842: 1840: 1822:10.1038/nrm1155 1800: 1796: 1742: 1738: 1728: 1726: 1694:(5938): 67–69. 1678: 1674: 1623: 1619: 1609: 1607: 1575: 1571: 1561: 1559: 1519: 1515: 1454: 1450: 1440: 1438: 1399: 1395: 1385: 1383: 1335: 1331: 1321: 1319: 1287: 1280: 1270: 1268: 1255: 1254: 1250: 1240: 1238: 1229: 1228: 1221: 1211: 1209: 1196: 1195: 1191: 1181: 1179: 1166: 1165: 1152: 1142: 1140: 1127: 1126: 1119: 1080: 1067: 1038: 1034: 1024: 1022: 1018: 1007: 1003: 1002: 991: 981: 979: 964: 963: 956: 946: 944: 931: 930: 926: 921: 909: 869:Honorary Fellow 815:Knight Bachelor 706: 679: 674: 661:With help from 642:into a form of 539:salivary glands 522:when he was at 516: 500:cell signalling 493:Trinity College 411: 381:'s research on 355:), earning his 318: 302:plasma membrane 267: 230: 211: 207: 203: 189: 168: 164: 160: 156: 152: 150:Knight Bachelor 148: 144: 125: 105: 86: 77: 73: 68: 67:22 October 1938 62: 60: 59: 58: 48: 35: 33: 24: 17: 12: 11: 5: 4397: 4387: 4386: 4381: 4376: 4371: 4366: 4361: 4356: 4351: 4346: 4341: 4336: 4331: 4326: 4321: 4316: 4311: 4306: 4301: 4296: 4291: 4286: 4281: 4276: 4271: 4266: 4249: 4248: 4246: 4245: 4239: 4233: 4227: 4224:Van Oldenborgh 4221: 4215: 4209: 4203: 4197: 4191: 4185: 4179: 4173: 4167: 4161: 4155: 4149: 4142: 4140: 4136: 4135: 4133: 4132: 4126: 4120: 4114: 4108: 4102: 4096: 4090: 4083: 4081: 4077: 4076: 4074: 4073: 4067: 4061: 4055: 4049: 4043: 4037: 4031: 4025: 4019: 4013: 4007: 4001: 3995: 3989: 3983: 3976: 3974: 3970: 3969: 3967: 3966: 3960: 3954: 3948: 3942: 3936: 3930: 3924: 3918: 3912: 3906: 3900: 3894: 3888: 3882: 3876: 3869: 3867: 3863: 3862: 3860: 3859: 3853: 3847: 3841: 3835: 3829: 3823: 3817: 3811: 3805: 3799: 3793: 3787: 3781: 3775: 3769: 3763: 3756: 3754: 3750: 3749: 3747: 3746: 3740: 3734: 3728: 3722: 3716: 3710: 3704: 3698: 3692: 3686: 3680: 3674: 3668: 3662: 3656: 3650: 3644: 3634: 3628: 3622: 3616: 3610: 3604: 3598: 3591: 3589: 3585: 3584: 3577: 3576: 3569: 3562: 3554: 3545: 3544: 3542: 3541: 3535: 3532:Shing-Tung Yau 3525: 3515: 3505: 3495: 3489: 3483: 3473: 3467: 3464:Henryk Iwaniec 3457: 3454:George Lusztig 3451: 3445: 3439: 3429: 3423: 3413: 3410:Ludwig Faddeev 3403: 3400:Richard Taylor 3393: 3383: 3377: 3370: 3368: 3362: 3361: 3359: 3358: 3355:Swee Lay Thein 3348: 3341:Patrick Cramer 3338: 3328: 3322: 3315:Peter Hegemann 3308: 3302: 3296: 3289:Ian R. Gibbons 3286: 3276: 3269:Bonnie Bassler 3266: 3259:Kazutoshi Mori 3256: 3242: 3232: 3221:Jules Hoffmann 3218: 3212: 3202: 3188: 3182: 3176: 3170: 3151: 3149: 3143: 3142: 3140: 3139: 3133: 3126:Duncan Lorimer 3122:Matthew Bailes 3119: 3109: 3102:Victoria Kaspi 3099: 3093: 3087: 3081: 3075: 3061: 3055: 3041: 3038:John F. Hawley 3031: 3021: 3018:Gerald Fishman 3011: 2997: 2991: 2985: 2979: 2965: 2958:Geoffrey Marcy 2955: 2948: 2946: 2942: 2941: 2933: 2932: 2925: 2918: 2910: 2901: 2900: 2898: 2897: 2887: 2881: 2878:Adrian Krainer 2867: 2856: 2854: 2850: 2849: 2847: 2846: 2840: 2834: 2831:C. Ronald Kahn 2824: 2810: 2796: 2790: 2780: 2773: 2771: 2767: 2766: 2764: 2763: 2753: 2739: 2736:Roger Y. Tsien 2729: 2722:Mario Capecchi 2715: 2704: 2702: 2698: 2697: 2695: 2694: 2688: 2678: 2672: 2666: 2656: 2650: 2647:Seymour Benzer 2644: 2641:Maclyn McCarty 2637: 2635: 2631: 2630: 2628: 2627: 2617: 2607: 2597: 2594:Osamu Hayaishi 2591: 2585: 2582:James W. Black 2571: 2561: 2550:CĂ©sar Milstein 2546: 2544: 2540: 2539: 2537: 2536: 2529:Arvid Carlsson 2522: 2507: 2505: 2501: 2500: 2492: 2491: 2484: 2477: 2469: 2461: 2460: 2434: 2404: 2374: 2344: 2314: 2284: 2254: 2222: 2202: 2176: 2146: 2116: 2086: 2060: 2030: 2000: 1970: 1940: 1910: 1880: 1850: 1816:(7): 517–529. 1794: 1736: 1672: 1643:(2): 473–482. 1617: 1569: 1513: 1474:(3): 553–557. 1448: 1415:(1): 139–153. 1393: 1329: 1303:(2): 201–210. 1278: 1248: 1219: 1189: 1150: 1117: 1065: 1032: 989: 954: 923: 922: 920: 917: 908: 907: 900: 895:Member of the 893: 887: 880: 866: 859: 849: 843: 833: 822: 812: 806: 800: 794: 784: 778: 775: 765: 759: 753: 748:Member of the 746: 740: 734: 728: 722: 707: 705: 702: 677: 672: 520:cell signaling 515: 512: 504:Portland Press 453:. He became a 410: 407: 389:to study with 387:United Kingdom 317: 314: 290:cell signaling 260: 259: 256: 255: 253:Antony Galione 250: 246: 245: 240: 234: 233: 222: 216: 215: 198: 194: 193: 184: 180: 179: 173: 172: 139: 135: 134: 122:Cell signaling 119: 118:Known for 115: 114: 95: 91: 90: 89:(aged 81) 83: 79: 78: 69: 56: 54: 50: 49: 34: 31: 15: 9: 6: 4: 3: 2: 4396: 4385: 4382: 4380: 4377: 4375: 4372: 4370: 4367: 4365: 4362: 4360: 4357: 4355: 4352: 4350: 4347: 4345: 4342: 4340: 4337: 4335: 4332: 4330: 4327: 4325: 4322: 4320: 4317: 4315: 4312: 4310: 4307: 4305: 4302: 4300: 4297: 4295: 4292: 4290: 4287: 4285: 4282: 4280: 4277: 4275: 4272: 4270: 4267: 4265: 4262: 4261: 4259: 4243: 4240: 4237: 4234: 4231: 4228: 4225: 4222: 4219: 4216: 4213: 4210: 4207: 4204: 4201: 4198: 4195: 4192: 4189: 4186: 4183: 4180: 4177: 4176:Van de Pavert 4174: 4171: 4168: 4165: 4162: 4159: 4156: 4153: 4150: 4147: 4144: 4143: 4141: 4137: 4130: 4127: 4124: 4121: 4118: 4115: 4112: 4109: 4106: 4103: 4100: 4097: 4094: 4091: 4088: 4085: 4084: 4082: 4078: 4071: 4068: 4065: 4062: 4059: 4056: 4053: 4050: 4047: 4044: 4041: 4038: 4035: 4032: 4029: 4026: 4023: 4020: 4017: 4014: 4011: 4008: 4005: 4002: 3999: 3996: 3993: 3990: 3987: 3984: 3981: 3978: 3977: 3975: 3971: 3964: 3961: 3958: 3955: 3952: 3949: 3946: 3943: 3940: 3937: 3934: 3931: 3928: 3925: 3922: 3919: 3916: 3913: 3910: 3907: 3904: 3901: 3898: 3895: 3892: 3889: 3886: 3883: 3880: 3877: 3874: 3871: 3870: 3868: 3864: 3857: 3854: 3851: 3848: 3845: 3842: 3839: 3836: 3833: 3830: 3827: 3824: 3821: 3818: 3815: 3812: 3809: 3806: 3803: 3800: 3797: 3794: 3791: 3788: 3785: 3782: 3779: 3776: 3773: 3770: 3767: 3764: 3761: 3758: 3757: 3755: 3751: 3744: 3741: 3738: 3735: 3732: 3729: 3726: 3723: 3720: 3717: 3714: 3711: 3708: 3705: 3702: 3699: 3696: 3693: 3690: 3687: 3684: 3681: 3678: 3675: 3672: 3669: 3666: 3663: 3660: 3657: 3654: 3651: 3648: 3645: 3642: 3638: 3635: 3632: 3629: 3626: 3623: 3620: 3617: 3614: 3611: 3608: 3605: 3602: 3599: 3596: 3593: 3592: 3590: 3586: 3582: 3575: 3570: 3568: 3563: 3561: 3556: 3555: 3552: 3539: 3536: 3533: 3529: 3526: 3523: 3519: 3516: 3513: 3509: 3506: 3503: 3502:David Kazhdan 3499: 3496: 3493: 3490: 3487: 3484: 3481: 3480:Claire Voisin 3477: 3474: 3471: 3470:Nigel Hitchin 3468: 3465: 3461: 3460:Gerd Faltings 3458: 3455: 3452: 3449: 3446: 3443: 3440: 3437: 3433: 3430: 3427: 3426:Jean Bourgain 3424: 3421: 3417: 3414: 3411: 3407: 3404: 3401: 3397: 3394: 3391: 3387: 3386:David Mumford 3384: 3381: 3378: 3375: 3372: 3371: 3369: 3363: 3356: 3352: 3349: 3346: 3342: 3339: 3336: 3332: 3329: 3326: 3323: 3320: 3316: 3312: 3309: 3306: 3303: 3300: 3297: 3294: 3290: 3287: 3284: 3280: 3277: 3274: 3270: 3267: 3264: 3260: 3257: 3254: 3250: 3246: 3243: 3240: 3236: 3233: 3230: 3229:Bruce Beutler 3226: 3222: 3219: 3216: 3213: 3210: 3206: 3203: 3200: 3196: 3192: 3189: 3186: 3183: 3180: 3179:Xiaodong Wang 3177: 3174: 3171: 3168: 3164: 3160: 3159:Herbert Boyer 3156: 3153: 3152: 3150: 3144: 3137: 3134: 3131: 3127: 3123: 3120: 3117: 3113: 3110: 3107: 3103: 3100: 3097: 3094: 3091: 3088: 3085: 3082: 3079: 3076: 3073: 3069: 3065: 3064:Ronald Drever 3062: 3059: 3056: 3053: 3049: 3045: 3042: 3039: 3035: 3034:Steven Balbus 3032: 3029: 3025: 3022: 3019: 3015: 3012: 3009: 3008:David Spergel 3005: 3001: 2998: 2995: 2992: 2989: 2986: 2983: 2980: 2977: 2976:Brian Schmidt 2973: 2969: 2966: 2963: 2959: 2956: 2953: 2950: 2949: 2947: 2943: 2938: 2931: 2926: 2924: 2919: 2917: 2912: 2911: 2908: 2895: 2891: 2888: 2885: 2882: 2879: 2875: 2871: 2868: 2865: 2861: 2858: 2857: 2855: 2851: 2844: 2841: 2838: 2835: 2832: 2828: 2825: 2822: 2818: 2814: 2811: 2808: 2807:Victor Ambros 2804: 2800: 2797: 2794: 2791: 2788: 2784: 2781: 2778: 2775: 2774: 2772: 2768: 2761: 2757: 2754: 2751: 2747: 2743: 2740: 2737: 2733: 2730: 2727: 2723: 2719: 2716: 2713: 2709: 2708:Avram Hershko 2706: 2705: 2703: 2699: 2692: 2689: 2686: 2682: 2679: 2676: 2673: 2670: 2667: 2664: 2660: 2657: 2654: 2653:Judah Folkman 2651: 2648: 2645: 2642: 2639: 2638: 2636: 2632: 2625: 2621: 2618: 2615: 2611: 2610:Henri G. Hers 2608: 2605: 2601: 2598: 2595: 2592: 2589: 2586: 2583: 2579: 2575: 2572: 2569: 2565: 2562: 2559: 2555: 2551: 2548: 2547: 2545: 2541: 2534: 2530: 2526: 2523: 2520: 2516: 2512: 2509: 2508: 2506: 2502: 2498: 2490: 2485: 2483: 2478: 2476: 2471: 2470: 2467: 2448: 2444: 2438: 2422: 2418: 2414: 2408: 2392: 2388: 2384: 2378: 2362: 2358: 2354: 2348: 2332: 2328: 2324: 2318: 2302: 2298: 2294: 2288: 2272: 2268: 2264: 2258: 2242: 2238: 2237: 2232: 2226: 2218: 2217: 2212: 2206: 2190: 2186: 2180: 2164: 2160: 2156: 2150: 2134: 2130: 2126: 2120: 2104: 2100: 2099:Royal Society 2096: 2090: 2074: 2070: 2064: 2048: 2044: 2040: 2034: 2018: 2014: 2010: 2004: 1988: 1984: 1980: 1974: 1958: 1954: 1950: 1944: 1928: 1924: 1920: 1914: 1898: 1894: 1890: 1884: 1868: 1864: 1863:Royal Society 1860: 1854: 1839: 1835: 1831: 1827: 1823: 1819: 1815: 1811: 1810: 1805: 1798: 1790: 1786: 1782: 1778: 1774: 1770: 1766: 1762: 1758: 1754: 1750: 1746: 1740: 1725: 1721: 1717: 1713: 1709: 1705: 1701: 1697: 1693: 1689: 1688: 1683: 1676: 1668: 1664: 1659: 1654: 1650: 1646: 1642: 1638: 1637: 1632: 1628: 1621: 1606: 1602: 1598: 1594: 1591:(1): 81–147. 1590: 1586: 1585: 1580: 1573: 1558: 1554: 1550: 1546: 1542: 1538: 1535:(1): 91–104. 1534: 1530: 1529: 1524: 1517: 1509: 1505: 1500: 1495: 1490: 1485: 1481: 1477: 1473: 1469: 1468: 1463: 1459: 1452: 1436: 1432: 1428: 1423: 1418: 1414: 1410: 1409: 1404: 1397: 1382: 1378: 1374: 1370: 1366: 1362: 1358: 1354: 1350: 1346: 1345: 1340: 1333: 1318: 1314: 1310: 1306: 1302: 1298: 1297: 1292: 1285: 1283: 1266: 1262: 1258: 1252: 1236: 1232: 1226: 1224: 1207: 1203: 1199: 1193: 1177: 1173: 1169: 1163: 1161: 1159: 1157: 1155: 1138: 1134: 1130: 1124: 1122: 1113: 1109: 1104: 1099: 1095: 1091: 1090: 1085: 1078: 1076: 1074: 1072: 1070: 1060: 1055: 1051: 1047: 1043: 1036: 1017: 1013: 1006: 1000: 998: 996: 994: 977: 973: 972: 971:The Telegraph 967: 961: 959: 942: 938: 934: 928: 924: 916: 914: 905: 901: 898: 894: 891: 888: 885: 881: 878: 874: 870: 867: 864: 860: 857: 853: 850: 847: 844: 841: 837: 834: 831: 827: 823: 820: 816: 813: 810: 807: 804: 801: 798: 795: 792: 788: 785: 782: 779: 776: 773: 769: 766: 763: 760: 757: 754: 751: 747: 744: 741: 738: 735: 732: 729: 726: 723: 720: 716: 715:Royal Society 712: 709: 708: 701: 699: 695: 691: 687: 683: 675: 668: 664: 659: 657: 654:. He applied 653: 649: 645: 641: 637: 636:cell membrane 633: 629: 625: 620: 618: 614: 610: 606: 601: 599: 595: 589: 587: 583: 579: 575: 571: 567: 563: 558: 556: 552: 548: 547:physiological 544: 540: 536: 532: 529: 525: 521: 511: 509: 505: 501: 496: 494: 489: 486: 481: 479: 475: 471: 470:John Treherne 466: 464: 460: 456: 452: 448: 444: 440: 436: 432: 431:United States 428: 424: 420: 416: 406: 404: 400: 396: 392: 388: 384: 380: 377: 373: 368: 366: 362: 358: 354: 350: 346: 342: 339: 335: 331: 327: 323: 313: 311: 307: 303: 299: 295: 291: 287: 283: 278: 274: 270: 266: 257: 254: 251: 247: 244: 241: 239: 235: 228: 227: 223: 221: 217: 214: 210: 206: 202: 199: 195: 192: 188: 185: 181: 178: 174: 171: 167: 163: 159: 155: 151: 147: 143: 140: 136: 133: 129: 126:Discovery of 123: 120: 116: 112: 108: 103: 99: 96: 92: 84: 80: 76: 72: 55: 51: 46: 42: 38: 29: 26: 22: 21:Mike Berridge 4236:Van Lieshout 4230:Dröge Wendel 3664: 3538:Peter Sarnak 3512:Jeff Cheeger 3476:János Kollár 3448:David Donoho 3380:Andrew Wiles 3365:Mathematical 3325:Scott D. Emr 3263:Peter Walter 3215:David Julius 3172: 3167:Richard Doll 3163:Yuet-Wai Kan 3148:and medicine 3146:Life science 3072:Rainer Weiss 3014:Enrico Costa 2962:Michel Mayor 2890:Botond Roska 2813:John Kappler 2777:Axel Ullrich 2760:Aharon Razin 2756:Howard Cedar 2681:Michael Sela 2675:Mary F. Lyon 2658: 2604:Meir Wilchek 2525:Roger Sperry 2515:Jean Dausset 2511:George Snell 2451:. Retrieved 2447:the original 2437: 2425:. Retrieved 2421:the original 2407: 2395:. Retrieved 2391:the original 2377: 2365:. Retrieved 2361:the original 2347: 2335:. Retrieved 2331:the original 2317: 2305:. Retrieved 2301:the original 2287: 2275:. Retrieved 2271:the original 2257: 2245:. Retrieved 2241:the original 2234: 2225: 2214: 2205: 2193:. Retrieved 2189:the original 2179: 2167:. Retrieved 2163:the original 2149: 2137:. Retrieved 2133:the original 2119: 2107:. Retrieved 2103:the original 2089: 2077:. Retrieved 2073:the original 2063: 2051:. Retrieved 2047:the original 2033: 2021:. Retrieved 2017:the original 2013:Lasker Award 2003: 1991:. Retrieved 1987:the original 1973: 1961:. Retrieved 1957:the original 1943: 1931:. Retrieved 1927:the original 1913: 1901:. Retrieved 1897:the original 1883: 1871:. Retrieved 1867:the original 1853: 1841:. Retrieved 1813: 1807: 1797: 1756: 1752: 1739: 1727:. Retrieved 1691: 1685: 1675: 1640: 1634: 1620: 1608:. Retrieved 1588: 1582: 1572: 1560:. Retrieved 1532: 1526: 1516: 1471: 1465: 1451: 1439:. Retrieved 1435:the original 1412: 1406: 1396: 1384:. Retrieved 1348: 1342: 1332: 1320:. Retrieved 1300: 1294: 1269:. Retrieved 1265:the original 1251: 1239:. Retrieved 1235:the original 1210:. Retrieved 1206:the original 1192: 1180:. Retrieved 1176:the original 1141:. Retrieved 1137:the original 1093: 1087: 1049: 1045: 1035: 1023:. Retrieved 1016:the original 980:. Retrieved 976:the original 969: 945:. Retrieved 941:the original 927: 910: 809:Massry Prize 660: 656:lithium ions 621: 605:calcium ions 602: 590: 559: 517: 497: 490: 482: 467: 421:) after his 412: 383:tsetse flies 369: 319: 306:calcium ions 282:physiologist 264: 263: 224: 197:Institutions 191:Biochemistry 176: 87:(2020-02-13) 25: 4269:2020 deaths 4264:1938 births 4040:McKitterick 3986:Van der Wee 3345:Eva Nogales 3319:Georg Nagel 3305:Maria Jasin 3293:Ronald Vale 3283:Huda Zoghbi 3279:Adrian Bird 3078:Simon White 2952:Jim Peebles 2870:Joan Steitz 2803:Gary Ruvkun 2750:Tony Pawson 2691:Eric Kandel 2620:John Gurdon 2453:11 November 2397:20 November 2367:20 November 2337:20 November 2307:14 November 2277:20 November 2247:14 November 2211:"No. 54993" 2195:14 November 2169:14 November 2139:14 November 2109:20 November 2053:17 November 1993:17 November 1963:14 November 1933:14 November 1903:14 November 1873:17 November 1843:19 December 1729:19 December 1610:29 November 1562:29 November 1441:28 November 1386:23 November 1322:23 November 1271:19 December 1241:11 November 1212:11 November 1096:(1): 1–21. 982:27 February 781:Royal Medal 648:diglyceride 632:Ca channels 338:high school 162:Royal Medal 4258:Categories 4194:Van Golden 4111:McClelland 3927:Brunekreef 3856:Deisseroth 3778:Montagnier 3619:Van Deenen 3390:Wentsun Wu 3191:Ian Wilmut 3068:Kip Thorne 3048:Shaun Cole 3004:Lyman Page 2972:Adam Riess 2937:Shaw Prize 2685:Ruth Arnon 2427:2 November 2079:29 January 2023:2 November 1182:8 November 1143:7 November 1133:Shaw Prize 1025:3 November 947:6 November 919:References 756:Baly Medal 640:hydrolysed 613:sabbatical 582:difference 570:epithelium 549:effect as 531:cyclic AMP 506:under the 449:Center of 376:physiology 296:acts as a 286:biochemist 187:Physiology 63:1938-10-22 4218:Struycken 4206:B. Visser 4200:Koelewijn 4158:C. Visser 4123:Kanwisher 4099:Tomasello 4016:Schilling 3903:HarremoĂ«s 3850:Carmeliet 3808:Blackburn 3760:Lauterbur 3641:Reichardt 3631:Weissmann 3518:Noga Alon 2994:Frank Shu 2945:Astronomy 2939:laureates 2554:Leo Sachs 1296:BioEssays 1052:: 69–93. 551:serotonin 468:In 1969, 405:in 1965. 379:professor 367:in 1960. 365:chemistry 124:research 94:Education 4087:Anderson 4010:De Vries 3963:Le QuĂ©rĂ© 3939:Laurance 3909:Thompson 3873:Lovelock 3826:Steinman 3790:Marshall 3766:Van Rood 3753:Medicine 3743:Stillman 3719:De Lange 3701:Jeffreys 3665:Berridge 3595:Chargaff 3028:Jane Luu 2728:(2002/3) 2677:(1996/7) 2671:(1995/6) 2665:(1994/5) 2590:(1984/5) 1830:12838335 1747:(1984). 1557:38874406 1460:(1972). 1381:45803569 1317:15666351 1112:15709950 879:) (2000) 793:) (1991) 652:inositol 543:blow fly 514:Research 419:Zimbabwe 334:Zimbabwe 4212:Manders 4170:Martens 4146:Verhoef 4129:Zatorre 4093:Dehaene 4064:McNeill 4052:Assmann 4022:Le Goff 3998:Oberman 3973:History 3897:Ehrlich 3879:Branica 3844:Jackson 3838:Alitalo 3832:Clevers 3784:De Wied 3772:Moncada 3707:Szostak 3683:Rothman 3613:De Duve 3601:Brachet 3367:science 1838:1152297 1789:4240505 1781:6232463 1761:Bibcode 1724:4359904 1716:6605482 1696:Bibcode 1667:6309146 1658:1152070 1549:6266901 1508:4335064 1476:Bibcode 1431:4339528 1373:4300804 1353:Bibcode 1344:Science 871:of the 854:of the 838:of the 770:of the 713:of the 634:on the 586:charged 578:osmosis 478:Zoology 463:Biology 437:of the 435:Biology 361:zoology 341:biology 336:). His 322:Gatooma 273:FMedSci 71:Gatooma 41:FMedSci 4244:(2020) 4238:(2018) 4232:(2016) 4226:(2014) 4220:(2012) 4214:(2010) 4208:(2008) 4202:(2006) 4196:(2004) 4190:(2002) 4184:(2000) 4182:Geelen 4178:(1998) 4172:(1996) 4166:(1994) 4164:Röling 4160:(1992) 4154:(1990) 4148:(1988) 4131:(2020) 4125:(2018) 4119:(2016) 4117:Spelke 4113:(2014) 4107:(2012) 4105:Duncan 4101:(2010) 4095:(2008) 4089:(2006) 4072:(2020) 4070:Daston 4066:(2018) 4060:(2016) 4058:Herrin 4054:(2014) 4048:(2012) 4046:Parker 4042:(2010) 4036:(2008) 4034:Israel 4030:(2006) 4024:(2004) 4018:(2002) 4012:(2000) 4006:(1998) 4000:(1996) 3994:(1994) 3988:(1992) 3982:(1990) 3965:(2020) 3959:(2018) 3957:Hebert 3953:(2016) 3947:(2014) 3941:(2012) 3935:(2010) 3933:Tilman 3929:(2008) 3923:(2006) 3917:(2004) 3911:(2002) 3905:(2000) 3899:(1998) 3893:(1996) 3887:(1994) 3881:(1992) 3875:(1990) 3858:(2020) 3852:(2018) 3846:(2016) 3840:(2014) 3834:(2012) 3828:(2010) 3822:(2008) 3816:(2006) 3810:(2004) 3804:(2002) 3802:Selkoe 3798:(2000) 3796:Kandel 3792:(1998) 3786:(1996) 3780:(1994) 3774:(1992) 3768:(1990) 3762:(1989) 3745:(2020) 3739:(2018) 3737:Zhuang 3733:(2016) 3731:Doudna 3727:(2014) 3725:Dobson 3721:(2012) 3715:(2010) 3709:(2008) 3703:(2006) 3697:(2004) 3691:(2002) 3685:(2000) 3679:(1998) 3677:Pawson 3673:(1996) 3667:(1994) 3661:(1992) 3655:(1990) 3649:(1988) 3643:(1985) 3639:& 3637:Julesz 3633:(1982) 3627:(1979) 3621:(1976) 3615:(1973) 3609:(1970) 3607:Chance 3603:(1967) 3597:(1964) 3540:(2024) 3534:(2023) 3524:(2022) 3514:(2021) 3504:(2020) 3494:(2019) 3488:(2018) 3482:(2017) 3472:(2016) 3466:(2015) 3456:(2014) 3450:(2013) 3444:(2012) 3438:(2011) 3428:(2010) 3422:(2009) 3412:(2008) 3402:(2007) 3392:(2006) 3382:(2005) 3376:(2004) 3357:(2024) 3347:(2023) 3337:(2022) 3327:(2021) 3321:(2020) 3307:(2019) 3301:(2018) 3295:(2017) 3285:(2016) 3275:(2015) 3265:(2014) 3255:(2013) 3241:(2012) 3231:(2011) 3217:(2010) 3211:(2009) 3201:(2008) 3187:(2007) 3181:(2006) 3175:(2005) 3169:(2004) 3138:(2024) 3132:(2023) 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Index

Mike Berridge
FRS
FMedSci
FBPhS
Gatooma
Southern Rhodesia
University College of Rhodesia and Nyasaland
Bsc
University College
PhD
Cell signaling
inositol trisphosphate
second messenger
King Faisal International Prize in Science
Louis-Jeantet Prize for Medicine
Knight Bachelor
Canada Gairdner International Award
Albert Lasker Award for Basic Medical Research
Royal Medal
Dr H. P. Heineken Prize for Biochemistry and Biophysics
Shaw Prize in Life Science and Medicine
Physiology
Biochemistry
University of Virginia
Case Western Reserve University
University of Cambridge
Babraham Institute
Thesis
The physiology of excretion in the cotton stainer, Dysdercus fasciatus Signoret (Hemiptera, Pyrrhocoridae)
Doctoral advisor

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