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Matricellular protein

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307: 39:(ECM). Rather than serving as stable structural elements in the ECM, these proteins are rapidly turned over and have regulatory roles. They characteristically contain binding sites for ECM structural proteins and cell surface receptors, and may sequester and modulate activities of specific growth factors. 179: 372: 348: 17: 191: 43: 367: 143:
Bornstein P, Sage EH (October 2002). "Matricellular proteins: extracellular modulators of cell function".
341: 377: 322: 96:"Diversity of function is inherent in matricellular proteins: an appraisal of thrombospondin 1" 334: 36: 8: 282: 257: 233: 208: 120: 95: 258:"Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets" 156: 66:. Many of these proteins have important functions in wound healing and tissue repair. 287: 238: 187: 160: 125: 42:
Examples of matricellular proteins include the CCN family of proteins (also known as
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The Extracellular Matrix: an Overview (Biology of Extracellular Matrix)
55: 273: 59: 314: 47: 32: 306: 142: 177: 359: 171: 255: 209:"Emerging functions of matricellular proteins" 342: 249: 200: 136: 93: 349: 335: 206: 87: 31:is a dynamically expressed non-structural 281: 232: 119: 14: 360: 301: 180:"Chapter 11: Matricellular Proteins" 44:CCN intercellular signaling protein 24: 25: 389: 305: 256:Jun JI, Lau LF (December 2011). 13: 1: 373:Extracellular matrix proteins 157:10.1016/S0955-0674(02)00361-7 81: 321:. You can help Knowledge by 7: 207:Roberts DD (October 2011). 178:Roberts DD, Lau LF (2011). 94:Bornstein P (August 1995). 69: 10: 394: 300: 225:10.1007/s00018-011-0779-2 58:, SPARC family members, 35:that is present in the 368:Matricellular proteins 317:-related article is a 182:. In Mecham RP (ed.). 18:Matricellular proteins 145:Curr. Opin. Cell Biol 112:10.1083/jcb.130.3.503 29:matricellular protein 186:. Berlin: Springer. 37:extracellular matrix 262:Nat Rev Drug Discov 213:Cell. Mol. Life Sci 330: 329: 193:978-3-642-16554-2 16:(Redirected from 385: 351: 344: 337: 309: 302: 296: 295: 285: 253: 247: 246: 236: 204: 198: 197: 175: 169: 168: 140: 134: 133: 123: 91: 21: 393: 392: 388: 387: 386: 384: 383: 382: 358: 357: 356: 355: 299: 274:10.1038/nrd3599 254: 250: 205: 201: 194: 176: 172: 141: 137: 92: 88: 84: 72: 64:thrombospondins 23: 22: 15: 12: 11: 5: 391: 381: 380: 375: 370: 354: 353: 346: 339: 331: 328: 327: 310: 298: 297: 268:(12): 945–63. 248: 219:(19): 3133–6. 199: 192: 170: 135: 85: 83: 80: 79: 78: 71: 68: 9: 6: 4: 3: 2: 390: 379: 378:Protein stubs 376: 374: 371: 369: 366: 365: 363: 352: 347: 345: 340: 338: 333: 332: 326: 324: 320: 316: 311: 308: 304: 303: 293: 289: 284: 279: 275: 271: 267: 263: 259: 252: 244: 240: 235: 230: 226: 222: 218: 214: 210: 203: 195: 189: 185: 181: 174: 166: 162: 158: 154: 151:(5): 608–16. 150: 146: 139: 131: 127: 122: 117: 113: 109: 105: 101: 97: 90: 86: 77: 74: 73: 67: 65: 61: 57: 53: 49: 45: 40: 38: 34: 30: 19: 323:expanding it 312: 265: 261: 251: 216: 212: 202: 183: 173: 148: 144: 138: 106:(3): 503–6. 103: 100:J. Cell Biol 99: 89: 41: 28: 26: 76:CCN protein 52:osteopontin 362:Categories 82:References 62:(s), and 56:periostin 292:22129992 243:21833584 165:12231357 70:See also 60:tenascin 48:fibulins 315:protein 283:3663145 234:3556643 130:7542656 121:2120533 33:protein 290:  280:  241:  231:  190:  163:  128:  118:  313:This 319:stub 288:PMID 239:PMID 188:ISBN 161:PMID 126:PMID 278:PMC 270:doi 229:PMC 221:doi 153:doi 116:PMC 108:doi 104:130 46:), 364:: 286:. 276:. 266:10 264:. 260:. 237:. 227:. 217:68 215:. 211:. 159:. 149:14 147:. 124:. 114:. 102:. 98:. 54:, 50:, 27:A 350:e 343:t 336:v 325:. 294:. 272:: 245:. 223:: 196:. 167:. 155:: 132:. 110:: 20:)

Index

Matricellular proteins
protein
extracellular matrix
CCN intercellular signaling protein
fibulins
osteopontin
periostin
tenascin
thrombospondins
CCN protein
"Diversity of function is inherent in matricellular proteins: an appraisal of thrombospondin 1"
doi
10.1083/jcb.130.3.503
PMC
2120533
PMID
7542656
doi
10.1016/S0955-0674(02)00361-7
PMID
12231357
"Chapter 11: Matricellular Proteins"
ISBN
978-3-642-16554-2
"Emerging functions of matricellular proteins"
doi
10.1007/s00018-011-0779-2
PMC
3556643
PMID

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