949:. Microfluidic reaction chambers are difficult to scale up, since the entire point of microfluidics is to exploit the microscale behaviors of liquids. The only way around this obstacle is to run an extensive number of microfluidic reaction chambers in parallel, a novel task requiring custom-built equipment. For COVID-19 mRNA vaccines, this was the main manufacturing bottleneck. Pfizer used such a parallel approach to solve the scaling problem. After verifying that impingement jet mixers could not be directly scaled up, Pfizer made about 100 of the little mixers (each about the size of a
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914:. Encapsulating the mRNA molecule in lipid nanoparticles was a critical breakthrough for producing viable mRNA vaccines, solving a number of key technical barriers in delivering the mRNA molecule into the host cell. Research into using lipids to deliver siRNA to cells became a foundation for similar research into using lipids to deliver mRNA. However, new lipids had to be invented to encapsulate mRNA strands, which are much longer than siRNA strands.
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be approved, the story of mRNA vaccines starts more than 30 years ago, with many bumps in the road along the way. In 1990, the late physician-scientist Jon Wolff and his
University of Wisconsin colleagues injected mRNA into mice, which caused cells in the mice to produce the encoded proteins. In many ways, that work served as the first step toward making a vaccine from mRNA, but there was a long way to go—and there still is, for many applications.
96:
2460:"; (Quote: "The present invention relates to introduction of naked DNA and RNA sequences into a vertebrate to achieve controlled expression of a polypeptide. It is useful in gene therapy, vaccination, and any therapeutic situation in which a polypeptide should be administered to cells in vivo"; Example 8: mRNA vaccination of mice to produce the gpl20 protein of HIV virus); Priority date: 21 March 1989; Publication date: 4 October 1990.
1036:. Because mRNA vaccines are not constructed from an active pathogen (or even an inactivated pathogen), they are non-infectious. In contrast, traditional vaccines require the production of pathogens, which, if done at high volumes, could increase the risks of localized outbreaks of the virus at the production facility. Another biological advantage of mRNA vaccines is that since the antigens are produced inside the cell, they stimulate
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The Pfizer–BioNTech vaccine originally required 110 days to mass-produce (before Pfizer began to optimize the manufacturing process to only 60 days), which was substantially faster than traditional flu and polio vaccines. Within that larger timeframe, the actual production time is only about 22 days:
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When the broad range of vaccines against COVID-19 were being tested in clinical trials, only a few experts expected the unproven technology of mRNA to be the star. Within 10 months, mRNA vaccines were both the first to be approved and the most effective. Although these are the first mRNA vaccines to
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Before 2020, no mRNA technology platform (drug or vaccine) had been authorized for use in humans, so there was a risk of unknown effects. The 2020 COVID-19 pandemic required faster production capability of mRNA vaccines, made them attractive to national health organisations, and led to debate about
98:
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The COVID-19 mRNA vaccines from
Moderna and Pfizer–BioNTech have efficacy rates of 90 to 95 percent. Prior mRNA, drug trials on pathogens other than COVID-19 were not effective and had to be abandoned in the early phases of trials. The reason for the efficacy of the new mRNA vaccines is not clear.
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reduced inflammation but hasn't eliminated it completely", and that "this may also explain the intense reactions such as aches and fevers reported in some recipients of the mRNA SARS-CoV-2 vaccines". These reactions though severe were transient and another view is that they were believed to be a
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Another issue, with the large-scale use of this delivery method, is the availability of the novel lipids used to create lipid nanoparticles, especially ionizable cationic lipids. Before 2020, such lipids were manufactured in small quantities measured in grams or kilograms, and they were used for
855:
of naked mRNA for vaccination. A variety of methods have been used to deliver naked mRNA, such as subcutaneous, intravenous, and intratumoral injections. Although naked mRNA delivery causes an immune response, the effect is relatively weak, and after injection the mRNA is often rapidly degraded.
1213:
stated that the efficacy of the new COVID-19 mRNA vaccines could be due to the "sheer volume of resources" that went into development, or that the vaccines might be "triggering a nonspecific inflammatory response to the mRNA that could be heightening its specific immune response, given that the
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medical research and a handful of drugs for rare conditions. As the safety and efficacy of mRNA vaccines became clear in 2020, the few companies able to manufacture the requisite lipids were confronted with the challenge of scaling up production to respond to orders for several tons of lipids.
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reported, "While it's possible that differences in LNP formulations or mRNA secondary structures could account for the thermostability differences , many experts suspect both vaccine products will ultimately prove to have similar storage requirements and shelf lives under various temperature
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the mRNA fragments within a few days of introduction. Although non-immune cells can potentially also absorb vaccine mRNA, produce antigens, and display the antigens on their surfaces, dendritic cells absorb the mRNA globules much more readily. The mRNA fragments are translated in the
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mRNA vaccines use either non-amplifying (conventional) mRNA or self-amplifying mRNA. Pfizer–BioNTech and
Moderna vaccines use non-amplifying mRNA. Both mRNA types continue to be investigated as vaccine methods against other potential pathogens and cancer.
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that codes for the antigen of interest. The total amount of mRNA available to the cell is equal to the amount delivered by the vaccine. Dosage strength is limited by the amount of mRNA that can be delivered by the vaccine. Non-amplifying vaccines replace
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Strong but transient reactogenic effects were reported in trials of novel COVID-19 mRNA vaccines; most people will not experience severe side effects which include fever and fatigue. Severe side effects are defined as those that prevent daily activity.
1316:(and its helper proteins) which replicates the mRNA construct in the cell. This allows smaller vaccine doses. The mechanisms and consequently the evaluation of self-amplifying mRNA may be different, as self-amplifying mRNA is a much bigger molecule.
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Alberer M, Gnad-Vogt U, Hong HS, Mehr KT, Backert L, Finak G, et al. (September 2017). "Safety and immunogenicity of a mRNA rabies vaccine in healthy adults: an open-label, non-randomised, prospective, first-in-human phase 1 clinical trial".
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and began to invest in the field. DARPA grants were seen as a vote of confidence that in turn encouraged other government agencies and private investors to invest in mRNA technology. DARPA awarded at the time a $ 25 million grant to
Moderna.
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to make DNA from the RNA in the cell nucleus. A retrovirus has mechanisms to be imported into the nucleus, but other mRNA (such as the vaccine) lack these mechanisms. Once inside the nucleus, creation of DNA from RNA cannot occur without a
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1990:
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Weide B, Pascolo S, Scheel B, Derhovanessian E, Pflugfelder A, Eigentler TK, et al. (June 2009). "Direct injection of protamine-protected mRNA: results of a phase 1/2 vaccination trial in metastatic melanoma patients".
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vaccine can be stored between −25 and −15 °C (−13 and 5 °F), which is comparable to a home freezer, and that it remains stable between 2 and 8 °C (36 and 46 °F) for up to 30 days. In
November 2020,
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vaccine for COVID-19 in 2 days. They can also be manufactured faster, more cheaply, and in a more standardized fashion (with fewer error rates in production), which can improve responsiveness to serious outbreaks.
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Probst J, Weide B, Scheel B, Pichler BJ, Hoerr I, Rammensee HG, Pascolo S (August 2007). "Spontaneous cellular uptake of exogenous messenger RNA in vivo is nucleic acid-specific, saturable and ion dependent".
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virus, and viral proteins that may be less prone to genetic variation, to provide greater protection against SARS‑CoV‑2 variants. saRNA vaccines must use uridine, which is required for reproduction to occur.
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provides a layer of protection against degradation, allowing more robust translational output. In addition, the customization of the lipid's outer layer allows the targeting of desired cell types through
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transcribed mRNA with a chosen gene was able to deliver the genetic information to produce a desired protein within living cell tissue and led to the concept proposal of messenger RNA vaccines.
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5929:"First 'variant-proof' Covid vaccine starts trials in Manchester - Retired couple Andrew Clarke, 63, and his wife Helen, 64, from Bolton, became the first to receive the mRNA vaccine on Monday"
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may have an adverse reaction to messenger RNA vaccines. The advantages of mRNA vaccines over traditional vaccines are ease of design, speed and lower cost of production, the induction of both
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Weide B, Carralot JP, Reese A, Scheel B, Eigentler TK, Hoerr I, et al. (February–March 2008). "Results of the first phase I/II clinical vaccination trial with direct injection of mRNA".
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322:) began in 2013. Over the next few years, clinical trials of mRNA vaccines for a number of other viruses were started. mRNA vaccines for human use were studied for infectious agents such as
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in the 5'-untranslated region and the 3'-untranslated region can be altered, and the length of the poly(A) tail optimized, to stabilize the mRNA and increase protein production. The mRNA
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658:. By modifying these different components of the synthetic mRNA, the stability and translational ability of the mRNA can be enhanced, and in turn, the efficacy of the vaccine improved.
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to initiate an immune response. Dendritic cells can be collected from patients and programmed with the desired mRNA, then administered back into patients to create an immune response.
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at the beginning of 2020, led to the rapid development of the first approved mRNA vaccines. BioNTech and
Moderna in December of the same year obtained approval for their mRNA-based
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Martinon F, Krishnan S, Lenzen G, Magné R, Gomard E, Guillet JG, et al. (July 1993). "Induction of virus-specific cytotoxic T lymphocytes in vivo by liposome-entrapped mRNA".
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Various methods have been developed to overcome these delivery hurdles. The method of vaccine delivery can be broadly classified by whether mRNA transfer into cells occurs within (
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2449:; Inventors: Philip L. Felgner, Jon Asher Wolff, Gary H. Rhodes, Robert Wallace Malone, Dennis A. Carson; Assignees: Vical Inc., Wisconsin Alumni Research Foundation; Title: "
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Because mRNA is fragile, some vaccines must be kept at very low temperatures to avoid degrading and thus giving little effective immunity to the recipient. Pfizer–BioNTech's
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into a cell was published in 1989. "Naked" (or unprotected) lab-made mRNA was injected a year later into the muscle of mice. These studies were the first evidence that
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to stimulate production of the specific antigens. Entry of mRNA molecules, however, faces a number of difficulties. Not only are mRNA molecules too large to cross the
4979:"Influenza virus (A/HK/156/97) hemagglutinin expressed by an alphavirus replicon system protects chickens against lethal infection with Hong Kong-origin H5N1 viruses"
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is very rapidly degraded before it would have time to gain entry into the cell nucleus. In fact, mRNA vaccines must be stored at very low temperature and free from
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Conry RM, LoBuglio AF, Wright M, Sumerel L, Pike MJ, Johanning F, et al. (April 1995). "Characterization of a messenger RNA polynucleotide vaccine vector".
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interactions. However, many studies have also highlighted the difficulty of studying this type of delivery, demonstrating that there is an inconsistency between
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Other mRNA vaccines continue to be developed, since the approval of the first mRNA vaccines. Moderna announced the development of mRNA vaccines for 15 diseases:
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5177:"Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA"
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4930:"Intravenous administration of retroviral replicating vector, Toca 511, demonstrates therapeutic efficacy in orthotopic immune-competent mouse glioma model"
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1193:, and the person feeling as if they are as a result. To minimize this, mRNA sequences in mRNA vaccines are designed to mimic those produced by host cells.
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may have an adverse reaction to mRNA vaccines. The mRNA strands in the vaccine may elicit an unintended immune reaction – this entails the
953:), connected them together with pumps and filters with a "maze of piping," and set up a computer system to regulate flow and pressure through the mixers.
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applications of nanoparticles in terms of cellular intake. The nanoparticles can be administered to the body and transported via multiple routes, such as
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and the plasmid DNA, the mRNA can be transcribed in the lab. Efficacy of the vaccine is dependent on the stability and structure of the designed mRNA.
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Zhou X, Berglund P, Rhodes G, Parker SE, Jondal M, Liljeström P (December 1994). "Self-replicating
Semliki Forest virus RNA as recombinant vaccine".
1911:"The Advisory Committee on Immunization Practices' Interim Recommendation for Use of Pfizer-BioNTech COVID-19 Vaccine – United States, December 2020"
1262:, which both accompany a retrovirus, but which would not be present for other exogenous mRNA (such as a vaccine) even if it could enter the nucleus.
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5961:"Gritstone Announces Dosing of First Volunteer in Trial Evaluating Self-Amplifying mRNA as a COVID-19 Vaccine Booster and Immunogenicity Enhancer"
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then attach to the antigen and transport it to the cellular membrane, "activating" the dendritic cell. Once activated, dendritic cells migrate to
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Deering RP, Kommareddy S, Ulmer JB, Brito LA, Geall AJ (June 2014). "Nucleic acid vaccines: prospects for non-viral delivery of mRNA vaccines".
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2014:"The Advisory Committee on Immunization Practices' Interim Recommendation for Use of Moderna COVID-19 Vaccine – United States, December 2020"
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Once the viral antigens are produced by the host cell, the normal adaptive immune system processes are followed. Antigens are broken down by
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One issue with lipid nanoparticles is that several of the breakthroughs leading to the practical use of that technology involve the use of
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methods, particularly by avoiding the cost of harvesting and adapting dendritic cells from patients and by imitating a regular infection.
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mechanism can be added to amplify antigen translation and therefore immune response, decreasing the amount of starting material needed.
115:, the tendency of a vaccine to produce adverse reactions, is similar to that of conventional non-RNA vaccines. People susceptible to an
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2726:"Autologous dendritic cells transfected with prostate-specific antigen RNA stimulate CTL responses against metastatic prostate tumors"
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The mRNA can be improved by using synthetic 5'-cap analogues which enhance the stability and increase protein translation. Similarly,
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Berglund P, Smerdou C, Fleeton MN, Tubulekas I, Liljeström P (June 1998). "Enhancing immune responses using suicidal DNA vaccines".
4625:"A Direct Comparison of in Vitro and in Vivo Nucleic Acid Delivery Mediated by Hundreds of Nanoparticles Reveals a Weak Correlation"
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as a method to transport mRNA inside cells without setting off the body's defense system was reported. Clinical trial results of an
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of mRNA can be optimized for different purposes (a process called sequence engineering of mRNA), for example through enriching the
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2793:"Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA"
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2598:"A development that may evolve into a revolution in medicine: mRNA as the basis for novel, nucleotide-based vaccines and drugs"
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3690:"Vaccine formulations in clinical development for the prevention of severe acute respiratory syndrome coronavirus 2 infection"
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8957:
7322:
7250:
5241:
4593:
4101:
1699:
182:
995:, each of which can differ in structure and function. Clinical studies have utilized such viruses on a range of diseases in
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14771:
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14172:
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13536:
13261:
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10383:
10194:
10132:
9937:
9544:
9487:
9457:
9442:
9350:
6856:
4508:
4365:"Protein expression from exogenous mRNA: uptake by receptor-mediated endocytosis and trafficking via the lysosomal pathway"
1787:
1112:
stimulation to avoid immediate degradation and produce a more persistent effect through enhanced translation capacity. The
367:
132:
4682:"Opinion: A straightforward explanation why more COVID-19 vaccines can't be produced with help from 'dozens' of companies"
1979:"FDA Takes Additional Action in Fight Against COVID-19 By Issuing Emergency Use Authorization for Second COVID-19 Vaccine"
16805:
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15656:
15651:
15641:
15094:
15003:
14862:
14721:
12941:
12693:
12095:
11823:
11633:
11524:
11478:
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9422:
9097:
8999:
8895:
8671:
8614:
8068:
6888:
6645:
6571:
6424:
6139:
4250:"Intranodal vaccination with naked antigen-encoding RNA elicits potent prophylactic and therapeutic antitumoral immunity"
2439:
1541:
390:
277:
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6251:
16707:
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15176:
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11991:
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8313:
8229:
7424:
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5678:
1354:
1215:
5310:"Self-Amplifying RNA Vaccines Give Equivalent Protection against Influenza to mRNA Vaccines but at Much Lower Doses"
1783:
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3990:
1064:. The majority of the days needed for each production run are allocated to rigorous quality control at each stage.
950:
564:
531:
fragment of the RNA sequence of a virus into the individual being vaccinated. These mRNA fragments are taken up by
6171:
4205:
Benteyn D, Heirman C, Bonehill A, Thielemans K, Breckpot K (February 2015). "mRNA-based dendritic cell vaccines".
3299:
1876:"FDA Takes Key Action in Fight Against COVID-19 By Issuing Emergency Use Authorization for First COVID-19 Vaccine"
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to approve an mRNA vaccine, authorizing the Pfizer–BioNTech vaccine for widespread use. On 11 December, the US
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8173:
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8111:
8101:
6754:
6464:
6065:
3329:
Ball P (January 2021). "The lightning-fast quest for COVID vaccines — and what it means for other diseases".
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10228:
4289:
1320:
1312:. The first frame, like conventional mRNA, codes for the antigen of interest. The second frame codes for an
1308:
Self-amplifying mRNA (saRNA) vaccines replicate their mRNA after transfection. Self-amplifying mRNA has two
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8131:
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8053:
8048:
8018:
1984:
1881:
1313:
583:. This triggers the production of antibodies specifically targeted to the antigen, ultimately resulting in
244:
174:
827:, result in varying levels of mRNA uptake, making the choice of administration route a critical aspect of
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375:
178:
3061:"DARPA Awards Moderna Therapeutics A Grant For Up To $ 25 Million To Develop Messenger RNA Therapeutics"
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Schultz-Cherry S, Dybing JK, Davis NL, Williamson C, Suarez DL, Johnston R, Perdue ML (December 2000).
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307:
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for the Pfizer–BioNTech vaccine and a week later similarly authorized the
Moderna vaccine. In 2023 the
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5895:
1047:
mRNA vaccines have the production advantage that they can be designed swiftly. Moderna designed their
80:
that teaches the body to identify and destroy the corresponding pathogen or cancer cells. The mRNA is
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15520:
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15171:
14442:
13901:
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8437:
8400:
8272:
6926:
6134:
5450:"Moderna Announces Longer Shelf Life for its COVID-19 Vaccine Candidate at Refrigerated Temperatures"
5224:
Pardi N, Weissman D (17 December 2016). "Nucleoside
Modified mRNA Vaccines for Infectious Diseases".
2114:
903:
851:. This mode of mRNA uptake has been known since the 1990s. The first worldwide clinical studies used
643:
243:
in mice. The following year self-amplifying mRNA was developed by including both a viral antigen and
4131:
2961:"The story of mRNA: How a once-dismissed idea became a leading technology in the Covid vaccine race"
780:, a fairly inefficient pathway in the laboratory setting that can be significantly improved through
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15409:
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15384:
15374:
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14149:
13654:
13635:
13620:
13514:
13285:
8942:
6881:
6846:
6841:
6836:
5597:
1145:
mRNA vaccine has to be kept between −80 and −60 °C (−112 and −76 °F). Moderna says their
379:
77:
6114:
5513:
5020:"Recombinant vesicular stomatitis virus-based vaccines against Ebola and Marburg virus infections"
1909:
Oliver SE, Gargano JW, Marin M, Wallace M, Curran KG, Chamberland M, et al. (December 2020).
1056:
two weeks for molecular cloning of DNA plasmids and purification of DNA, four days for DNA-to-RNA
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15906:
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15379:
15234:
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7327:
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7037:
7009:
6971:
6966:
6946:
6474:
6163:
5072:
Dolgin E (November 2020). "COVID-19 vaccines poised for launch, but impact on pandemic unclear".
2349:
2089:
2012:
Oliver SE, Gargano JW, Marin M, Wallace M, Curran KG, Chamberland M, et al. (January 2021).
1652:
1057:
864:
609:
2140:
1287:
The initial mRNA vaccines use a non-amplifying mRNA construct. Non-amplifying mRNA has only one
1237:
There is misinformation implying that mRNA vaccines could alter DNA in the nucleus. mRNA in the
1157:
conditions." Several platforms are being studied that may allow storage at higher temperatures.
16627:
15404:
15356:
15327:
15274:
13295:
13112:
7308:
7237:
6236:
2013:
1297:
1060:
and purification of mRNA, and four days to encapsulate mRNA in lipid nanoparticles followed by
976:
486:
252:
6184:
2724:
Heiser A, Coleman D, Dannull J, Yancey D, Maurice MA, Lallas CD, et al. (February 2002).
214:
Timeline of some key discoveries and advances in the development of mRNA-based drug technology
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7137:
7132:
6588:
6534:
6444:
4623:
Paunovska K, Sago CD, Monaco CM, Hudson WH, Castro MG, Rudoltz TG, et al. (March 2018).
2207:
Initiation of cationic lipid-mediated mrna transfection; Concept proposal of mRNA-based drugs
1910:
1254:
1085:
907:
852:
678:
422:
410:
285:
5357:
4363:
Lorenz C, Fotin-Mleczek M, Roth G, Becker C, Dam TC, Verdurmen WP, et al. (July 2011).
4248:
Kreiter S, Selmi A, Diken M, Koslowski M, Britten CM, Huber C, et al. (November 2010).
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6439:
6390:
6357:
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Huang TT, Parab S, Burnett R, Diago O, Ostertag D, Hofman FM, et al. (February 2015).
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3095:
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812:
670:
572:
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5308:
Vogel AB, Lambert L, Kinnear E, Busse D, Erbar S, Reuter KC, et al. (February 2018).
8:
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194:
89:
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6524:
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6016:
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3803:
3640:
3612:"Evolution and Progress of mRNA Vaccines in the Treatment of Melanoma: Future Prospects"
3611:
3342:
3249:
3099:
2350:"After COVID-19 successes, researchers push to develop mRNA vaccines for other diseases"
2318:
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1124:
or choosing specific UTRs known to increase translation. An additional ORF coding for a
979:
to achieve similar immunological responses. Typical RNA viruses used as vectors include
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12902:
9756:
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is similar to that of conventional, non-RNA vaccines. However, those susceptible to an
1113:
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improves mRNA stability and half-life and, in turn, protein production. Replacing rare
651:
584:
15186:
6155:
5146:"From science to syringe: COVID-19 vaccines are miracles of science and supply chains"
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4169:
4107:
4097:
4084:
Fiedler K, Lazzaro S, Lutz J, Rauch S, Heidenreich R (2016). "MRNA Cancer
Vaccines".
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524:) into the body. These antigens and viruses are prepared and grown outside the body.
430:
347:
335:
310:. The agency recognized the potential of nucleic acid technology for defense against
162:
obtained authorization for their mRNA-based COVID-19 vaccines. On 2 December, the UK
120:
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16122:
12471:
7211:
6052:
5744:
5358:"Pfizer-BioNTech COVID-19 Vaccine Vaccination Storage & Dry Ice Safety Handling"
5294:
5228:. Methods in Molecular Biology. Vol. 1499. Springer New York. pp. 109–21.
4349:
4234:
3737:
Kyriakidis NC, López-Cortés A, González EV, Grimaldos AB, Prado EO (February 2021).
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1852:(Decision). Medicines & Healthcare Products Regulatory Agency. 8 December 2020.
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Crommelin DJ, Anchordoquy TJ, Volkin DB, Jiskoot W, Mastrobattista E (March 2021).
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1414:
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for the Pfizer–BioNTech COVID-19 vaccine and a week later similar approval for the
355:
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The first human clinical trials using an mRNA vaccine against an infectious agent (
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147:
124:
49:
16370:
6732:
5558:
4266:
4249:
3397:
1444:"Delivering the Messenger: Advances in Technologies for Therapeutic mRNA Delivery"
543:) to read the mRNA and produce the viral antigens that the mRNA encodes. The body
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10638:
10633:
7471:
7196:
6994:
6801:
6759:
6650:
6630:
6600:
6583:
6509:
6499:
6429:
6368:
6364:
6313:
6048:
5728:
5518:
4750:"Manufacturing moonshot: How Pfizer makes its millions of Covid-19 vaccine doses"
4648:
4418:
4218:
3812:
3565:
2899:
2809:
2792:
2457:
2446:
1519:
1332:
1210:
1171:
1125:
1109:
1061:
848:
781:
725:, they are also negatively charged like the cell membrane, which causes a mutual
505:
331:
140:
18305:
15312:
5325:
5233:
4093:
2997:"How a secretive Pentagon agency seeded the ground for a rapid coronavirus cure"
1691:
1459:
18298:
16562:
16532:
16490:
16412:
16280:
16217:
16202:
16177:
16157:
15725:
15289:
15209:
13811:
13392:
12688:
8872:
7333:
7060:
6951:
6911:
6791:
6617:
6556:
6024:
5862:
5485:
5081:
4513:
4469:
3956:
3871:
3846:
3754:
3705:
3579:
3560:
3350:
3258:
3233:
3202:
3107:
2965:
2236:
Proceedings of the National Academy of Sciences of the United States of America
1740:
1410:
1182:
996:
758:
726:
624:
532:
456:
449:
273:
112:
57:
16454:
16436:
6195:
4165:
3739:"SARS-CoV-2 vaccines strategies: a comprehensive review of phase 3 candidates"
2488:
1503:
298:
in 2010, were founded to develop mRNA biotechnologies. The US research agency
18320:
16642:
16612:
16580:
16466:
16358:
16334:
16251:
16222:
16197:
16172:
16162:
16142:
16117:
16107:
16097:
16034:
15959:
15947:
14431:
14290:
14246:
14231:
13856:
13851:
13781:
13686:
13382:
8850:
7216:
7201:
7171:
7166:
7021:
6774:
6769:
6678:
6323:
5813:"New crop of COVID-19 mRNA vaccines could be easier to store, cheaper to use"
4848:"Why grandparents can't find vaccines: Scarcity of niche biotech ingredients"
4173:
3630:
3405:
3267:
3115:
2788:
2749:
2702:
2613:
2033:
1748:
1605:
1328:
1324:
1105:
1081:
992:
918:
844:
824:
718:
705:
468:
303:
256:
190:
81:
45:
6578:
5776:
5759:
5481:"Experts Tell F.D.A. It Should Gather More Safety Data on Covid-19 Vaccines"
5420:
5388:"Why Does Pfizer's COVID-19 Vaccine Need To Be Kept Colder Than Antarctica?"
5035:
3531:"Moderna plots vaccines against 15 pathogens with future pandemic potential"
2853:
2836:
2326:
2256:
2231:
1279:
595:
259:
was shown to elicit a similar immune response against cancer cells in mice.
18331:
16647:
16574:
16508:
16460:
16448:
16442:
16400:
16382:
16212:
16192:
16152:
16127:
16077:
15322:
15307:
15249:
15239:
14528:
14206:
13886:
13836:
13791:
13776:
13694:
7293:
6936:
6831:
6764:
6705:
6276:
6256:
6088:
6032:
5880:
5795:
5736:
5698:
5566:
5545:
Wadman M (November 2020). "Public needs to prep for vaccine side effects".
5343:
5251:
5210:
5089:
5053:
5004:
4995:
4978:
4963:
4914:
4666:
4575:
4488:
4426:
4390:
4341:
4275:
4226:
4191:
4148:
Jackson NA, Kester KE, Casimiro D, Gurunathan S, DeRosa F (February 2020).
4111:
4070:
3975:
3924:
3831:
3772:
3723:
3663:
3649:
3588:
3438:
3423:
3358:
3285:
3210:
3167:
3123:
2907:
2872:
2818:
2767:
2710:
2631:
2531:
2496:
2422:
2294:
2202:
2052:
1949:
1930:
1822:
1766:
1709:
1623:
1528:
1477:
1428:
1242:
1186:
1093:
946:
872:
762:
730:
682:
655:
553:
536:
517:
438:
394:
223:
219:
116:
15865:
Inter-Agency Task Force for the Management of Emerging Infectious Diseases
5286:
5113:"Moderna's groundbreaking coronavirus vaccine was designed in just 2 days"
4895:
4594:"Without these lipid shells, there would be no mRNA vaccines for COVID-19"
4557:
4540:
Reichmuth AM, Oberli MA, Jaklenec A, Langer R, Blankschtein D (May 2016).
4381:
4364:
4333:
3847:"Tools for translation: non-viral materials for therapeutic mRNA delivery"
2658:
2582:
2539:
2334:
2275:
906:
as a drug delivery system was in 2018, when the agency approved the first
894:
197:
that enabled the development of effective mRNA vaccines against COVID-19.
16607:
16586:
16526:
16388:
16167:
16132:
16092:
16019:
15302:
15279:
15259:
15181:
14560:
14473:
14241:
14129:
14068:
13826:
13786:
13761:
13746:
13724:
13377:
12192:
7080:
7070:
6931:
6737:
6625:
6593:
6519:
6381:
6272:
6264:
5192:
4945:
4051:
4034:
3031:"DARPA's gambles might have created the best hopes for stopping COVID-19"
2403:
2386:
2227:
2183:
2166:
1597:
1349:
1253:
vaccines are single-stranded RNA) which enters the cell nucleus and uses
1073:
820:
816:
777:
713:
For a vaccine to be successful, sufficient mRNA must enter the host cell
560:
426:
414:
386:
136:
128:
73:
13345:
5278:
2115:"Hungarian and US scientists win Nobel for COVID-19 vaccine discoveries"
504:
Traditional vaccines stimulate an antibody response by injecting either
16713:
Tests, cases, tests per capita, cases per capita by country subdivision
16418:
16207:
16147:
16137:
16102:
15269:
14633:
14513:
14270:
13968:
13846:
13831:
13541:
13422:
13397:
7407:
7206:
7181:
6871:
6821:
4786:"Race to the Vaccine: A COVID-19 vaccine life cycle: from DNA to doses"
3736:
1246:
1121:
1108:, 2'-O-methylated nucleosides) can be incorporated to mRNA to suppress
1080:, mRNA vaccines also have additional advantages over DNA vaccines. The
1024:
988:
984:
980:
832:
686:
666:
634:
transcribed mRNA has the same structural components as natural mRNA in
568:
442:
92:
that protect the RNA strands and help their absorption into the cells.
5625:
3906:
1166:
the type of initial authorization mRNA vaccines should get (including
210:
21:
16622:
16514:
16484:
16394:
16029:
15457:
15264:
14600:
14580:
14483:
14426:
14384:
14119:
14099:
13816:
13806:
13736:
13699:
13453:
13432:
13417:
12997:
12823:
7461:
7255:
6826:
6699:
6268:
4035:"mRNA Vaccine Era—Mechanisms, Drug Platform and Clinical Prospection"
2741:
2387:"mRNA Vaccine Era-Mechanisms, Drug Platform and Clinical Prospection"
2167:"mRNA Vaccine Era-Mechanisms, Drug Platform and Clinical Prospection"
1146:
1048:
972:
876:
722:
714:
674:
647:
639:
549:
521:
358:. On 2 December, seven days after its final eight-week trial, the UK
323:
7356:
6079:
6060:
5760:"Enlisting the mRNA Vaccine Platform to Combat Parasitic Infections"
4150:"The promise of mRNA vaccines: a biotech and industrial perspective"
4088:. Recent Results in Cancer Research. Vol. 209. pp. 61–85.
2693:
2676:
1028:
Advantages and disadvantages of different types of vaccine platforms
552:
and do not affect the body's genomic DNA, located separately in the
497:. The markers on the pathogen that the antibodies target are called
16632:
16617:
14638:
14595:
14590:
14503:
14498:
14410:
14405:
14400:
14201:
14195:
14144:
13861:
13821:
13704:
7399:
7097:
7090:
7085:
7055:
6811:
6747:
6742:
6185:"Halting Progress and Happy Accidents: How mRNA Vaccines Were Made"
4976:
3086:
Dolgin E (September 2021). "The tangled history of mRNA vaccines".
1142:
911:
804:
approaches have been investigated. They offer some advantages over
796:
697:
frequently used by the host cell also enhances protein production.
621:
620:
and sequence which corresponds to the mRNA construct. By combining
605:
603:
The central component of a mRNA vaccine is its mRNA construct. The
540:
528:
494:
490:
453:
311:
291:
228:
155:
65:
1850:"Conditions of Authorisation for Pfizer/BioNTech COVID-19 Vaccine"
1335:. The vaccine is designed to target both the spike protein of the
800:
transcribed mRNA leads to the expression of antigens in the body,
16112:
15822:
14623:
14570:
14565:
14508:
14478:
14468:
14463:
14211:
14104:
14076:
6816:
6260:
3380:
Wherry EJ, Jaffee EM, Warren N, D'Souza G, Ribas A (April 2021).
1818:"UK approves Pfizer/BioNTech Covid vaccine for rollout next week"
1722:
1293:
1238:
1089:
1077:
1033:
1008:
1004:
883:
744:
738:
613:
498:
473:
406:
366:
to approve an mRNA vaccine, granting emergency authorization for
295:
286:
mRNA vaccine directly injected into the body against cancer cells
269:
255:
response against a viral pathogen. The next year mRNA encoding a
236:
159:
150:, messenger RNA vaccines have attracted considerable interest as
61:
53:
41:
4403:
4204:
3889:
Schlake T, Thess A, Fotin-Mleczek M, Kallen KJ (November 2012).
2451:
Expression of Exogenous Polynucleotide Sequences in a Vertebrate
2305:(March 1990). "Direct gene transfer into mouse muscle in vivo".
831:
delivery. One study showed, in comparing different routes, that
306:
research program ADEPT to develop emerging technologies for the
16009:
14628:
14544:
14518:
14421:
14379:
14251:
13771:
7119:
7104:
6395:
5758:
Versteeg L, Almutairi MM, Hotez PJ, Pollet J (September 2019).
5264:
4147:
3888:
1686:. Methods in Molecular Biology. Vol. 1499. pp. 1–11.
1502:
Verbeke R, Lentacker I, De Smedt SC, Dewitte H (October 2019).
1501:
1097:
923:
880:
766:
580:
576:
319:
280:) was started in 2001. Four years later, the successful use of
240:
5626:"Vaccine rumours debunked: Microchips, 'altered DNA' and more"
4879:"RNA Viruses as Tools in Gene Therapy and Vaccine Development"
3688:
Batty CJ, Heise MT, Bachelder EM, Ainslie KM (December 2020).
867:
can be mixed with mRNA to generate protective coatings called
709:
Major delivery methods and carrier molecules for mRNA vaccines
60:, which use the designed mRNA as a blueprint to build foreign
14488:
14358:
14308:
7114:
6999:
6605:
6539:
5175:
Karikó K, Muramatsu H, Ludwig J, Weissman D (November 2011).
5174:
4539:
4451:
Wang Y, Zhang Z, Luo J, Han X, Wei Y, Wei X (February 2021).
4362:
3379:
3189:
Dolgin E (November 2021). "mRNA flu shots move into trials".
1283:
Mechanism of non-amplifying and self-amplifying mRNA vaccines
1000:
690:
599:
mRNA components important for expressing the antigen sequence
398:
299:
69:
18293:
16266:(Executive Director of the WHO Health Emergencies Programme)
15829:
National Expert Group on Vaccine Administration for COVID-19
13552:
neurological, psychological and other mental health outcomes
5757:
4817:"mRNA Covid-19 Vaccines Are Fast to Make, but Hard to Scale"
247:
encoding gene. The method was used in mice to elicit both a
16708:
Tests, cases, tests per capita, cases per capita by country
15930:
14523:
7450:
7444:
6414:
6207:
6061:"mRNA-based therapeutics – developing a new class of drugs"
5714:
5421:"Fact Sheet for Healthcare Providers Administering Vaccine"
2930:"BioNTech's founders: scientist couple in global spotlight"
2677:"mRNA-based therapeutics — developing a new class of drugs"
2517:
1682:
Kramps T, Elders K (2017). "Introduction to RNA Vaccines".
327:
5844:
4247:
3687:
3467:
2723:
2644:
1174:) after the eight-week period of post-final human trials.
13085:
6211:
4622:
2783:
2475:
Pascolo S (August 2004). "Messenger RNA-based vaccines".
2011:
1908:
1441:
1032:
mRNA vaccines offer specific advantages over traditional
685:
impacts protein translation. Enriching the sequence with
402:
371:
85:
5307:
4318:
3382:"How Did We Get a COVID-19 Vaccine in Less Than 1 Year?"
3144:
2885:
2560:
2293:
1579:
1442:
Kowalski PS, Rudra A, Miao L, Anderson DG (April 2019).
108:
Video showing how vaccination with an mRNA vaccine works
5381:
5379:
4814:
4083:
3940:"Review the safety of Covid-19 mRNA vaccines: a review"
3664:"British man tests first personalised melanoma vaccine"
3439:"Covid Pfizer vaccine approved for use next week in UK"
2837:"An Update on Self-Amplifying mRNA Vaccine Development"
1725:"Addressing the Cold Reality of mRNA Vaccine Stability"
1580:
Pardi N, Hogan MJ, Porter FW, Weissman D (April 2018).
886:
and has been used to encapsulate mRNA for vaccination.
419:
Middle East respiratory syndrome coronavirus (MERS-CoV)
5847:"Self-amplifying RNA vaccines for infectious diseases"
5415:
5413:
4927:
4509:"How nanotechnology helps mRNA Covid-19 vaccines work"
794:
Since the discovery that the direct administration of
139:
before distribution, other mRNA vaccines, such as the
29:
transcription, innate and adaptive immunity activation
18270:
5653:"Retroviral DNA Transposition: Themes and Variations"
5514:"Pfizer boss warns on risk of fast-tracking vaccines"
3500:"Moderna Announces Its Global Public Health Strategy"
1072:
In addition to sharing the advantages of theoretical
15625:
Yeşilköy Prof. Dr. Murat Dilmener Emergency Hospital
5376:
5350:
1504:"Three decades of messenger RNA vaccine development"
1393:
Park KS, Sun X, Aikins ME, Moon JJ (December 2020).
539:. The dendritic cells use their internal machinery (
6183:Kolata, Gina; Mueller, Benjamin (15 January 2022).
6130:"Five things you need to know about: mRNA vaccines"
5845:Bloom K, van den Berg F, Arbuthnot P (April 2021).
5410:
4815:Hopkins JS, Eastwood J, Moriarty D (3 March 2021).
4716:"Why manufacturing Covid vaccines at scale is hard"
3529:Steenhuysen, Julie; Erman, Michael (8 March 2022).
527:In contrast, mRNA vaccines introduce a short-lived
362:(MHRA) became the first global medicines regulator
360:
Medicines and Healthcare products Regulatory Agency
164:
Medicines and Healthcare products Regulatory Agency
13752:Decentralized Privacy-Preserving Proximity Tracing
2218:
776:dendritic cells take up mRNA molecules is through
48:(mRNA) to produce an immune response. The vaccine
15757:Africa Centres for Disease Control and Prevention
15619:Sancaktepe Prof. Dr. Feriha Öz Emergency Hospital
7272:Cedillo v. Secretary of Health and Human Services
6047:
5623:
5110:
4542:"mRNA vaccine delivery using lipid nanoparticles"
3231:
2674:
1392:
1096:, and the risk of being integrated into the host
654:(ORF), which encodes the relevant antigen, and a
131:. While some messenger RNA vaccines, such as the
18318:
14545:Zhongyianke Biotech–Liaoning Maokangyuan Biotech
5111:Neilson S, Dunn A, Bendix A (26 November 2020).
5017:
4453:"mRNA vaccine: a potential therapeutic strategy"
3785:
3528:
2141:"The Nobel Prize in Physiology or Medicine 2023"
2090:"The Nobel Prize in Physiology or Medicine 2023"
1784:"UK authorises Pfizer/BioNTech COVID-19 vaccine"
835:injection leads to the largest T-cell response.
516:(dead) virus, or a recombinant antigen-encoding
15913:Great American Economic Revival Industry Groups
6197:M.I.T. Lecture 10: Kizzmekia Corbett, Vaccines"
4450:
3884:
3882:
3683:
3681:
3468:Office of the Commissioner (18 December 2020).
3232:Hou X, Zaks T, Langer R, Dong Y (August 2021).
1868:
1815:
1497:
1495:
1493:
1491:
1489:
1487:
1229:Misinformation related to the COVID-19 pandemic
1219:reaction to the lipid drug delivery molecules.
1092:, so there is no need for the RNA to enter the
276:transfected with mRNA encoding tumor antigens (
4783:
4033:Xu S, Yang K, Li R, Zhang L (September 2020).
2834:
2385:Xu S, Yang K, Li R, Zhang L (September 2020).
2165:Xu S, Yang K, Li R, Zhang L (September 2020).
1645:
1388:
1386:
1384:
1382:
1380:
859:
15613:Kandakadu Treatment and Rehabilitation Centre
9145:Community Activities Restrictions Enforcement
7372:
6237:
6182:
5644:
5258:
5223:
4032:
3844:
2384:
2232:"Cationic liposome-mediated RNA transfection"
2164:
1395:"Non-viral COVID-19 vaccine delivery systems"
1260:reverse transcriptase and appropriate primers
222:of designed mRNA packaged within a liposomal
16835:World map by countries: confirmed per capita
15780:National Institute for Communicable Diseases
8423:Saint Helena, Ascension and Tristan da Cunha
4077:
3879:
3678:
2675:Sahin U, Karikó K, Türeci Ö (October 2014).
1681:
1484:
889:
235:Liposome-encapsulated mRNA encoding a viral
16971:Morocco (including occupied Western Sahara)
15805:National COVID-19 Commission Advisory Board
15774:Korea Disease Control and Prevention Agency
5710:
5708:
5624:Carmichael F, Goodman J (2 December 2020).
4039:International Journal of Molecular Sciences
3937:
2835:Blakney AK, Ip S, Geall AJ (January 2021).
2391:International Journal of Molecular Sciences
2171:International Journal of Molecular Sciences
1377:
971:In addition to non-viral delivery methods,
902:The first time the FDA approved the use of
729:. Additionally, mRNA is easily degraded by
435:Severe fever with Thrombocytopenia syndrome
368:Pfizer–BioNTech's BNT162b2 COVID-19 vaccine
7379:
7365:
6244:
6230:
6176:Centers for Disease Control and Prevention
5385:
5067:
5065:
5063:
3786:Bull JJ, Nuismer SL, Antia R (July 2019).
3609:
3561:"Precision medicine meets cancer vaccines"
3304:Centers for Disease Control and Prevention
2595:
1582:"mRNA vaccines — a new era in vaccinology"
1319:SaRNA vaccines being researched include a
871:. These protect the recombinant mRNA from
485:The goal of a vaccine is to stimulate the
16254:(Team lead of WHO-China COVID-19 mission)
15835:COVID-19 Response Acceleration Task Force
6078:
5870:
5785:
5775:
5688:
5650:
5333:
5200:
5043:
5018:Geisbert TW, Feldmann H (November 2011).
4994:
4953:
4904:
4894:
4876:
4656:
4565:
4478:
4468:
4380:
4265:
4181:
4086:Current Strategies in Cancer Gene Therapy
4060:
4050:
3965:
3955:
3914:
3870:
3838:
3821:
3811:
3762:
3713:
3639:
3629:
3578:
3413:
3275:
3257:
3024:
3022:
2990:
2988:
2862:
2852:
2808:
2757:
2692:
2621:
2412:
2402:
2301:, Williams P, Chong W, Acsadi G, Jani A,
2289:
2287:
2285:
2265:
2255:
2192:
2182:
2042:
2032:
1939:
1929:
1842:
1816:Boseley S, Halliday J (2 December 2020).
1778:
1776:
1756:
1613:
1527:
1467:
1418:
1249:can be single-stranded RNA (just as many
15631:COVID-19 hospitals in the United Kingdom
12412:Gridirion football (NCAAF, NFL, and CFL)
8926:Dadra and Nagar Haveli and Daman and Diu
5705:
4784:Weise E, Weintraub K (7 February 2021).
4779:
4777:
4775:
4743:
4741:
4587:
4585:
4502:
4500:
4498:
3991:"How do the new COVID-19 vaccines work?"
3845:Hajj KA, Whitehead KA (September 2017).
2427:Concept proposal of mRNA vaccines (1990)
1811:
1809:
1331:of an saRNA COVID-19 vaccine, used as a
1278:
1023:
893:
704:
594:
520:(harmless carrier virus with an antigen
472:
370:for widespread use. On 11 December, the
350:, and sequencing of the causative virus
209:
94:
20:
15889:Imperial College COVID-19 Response Team
15853:Crisis Preparedness and Response Centre
13720:COVID-19 Contact-Confirming Application
6214:explaining how the vaccine works using
5926:
5511:
5060:
4845:
4839:
4808:
4709:
4707:
3988:
3553:
3436:
3234:"Lipid nanoparticles for mRNA delivery"
2474:
1435:
1019:
838:
76:. These protein molecules stimulate an
18319:
16260:(Technical Lead for COVID-19 response)
15526:Dabie Mountain Regional Medical Centre
12725:COVID-19 Pandemic Unemployment Payment
6172:"Understanding mRNA COVID-19 Vaccines"
5996:"The tangled history of mRNA vaccines"
5993:
5971:from the original on 22 September 2021
5941:from the original on 20 September 2021
5840:
5838:
5807:
5805:
5586:
5584:
5544:
5478:
5143:
5137:
5071:
4506:
3891:"Developing mRNA-vaccine technologies"
3788:"Recombinant vector vaccine evolution"
3188:
3085:
3019:
2985:
2958:
2952:
2670:
2668:
2282:
1773:
1641:
1639:
1637:
1635:
1633:
493:that precisely target that particular
44:that uses a copy of a molecule called
16684:
15989:
15877:Coronavirus Scientific Advisory Board
15841:National Public Health Emergency Team
15601:Malaysia Agro Exposition Park Serdang
15493:
15354:
13496:
12142:
7969:
7422:
7386:
7360:
6225:
5671:10.1128/microbiolspec.MDNA3-0005-2014
5526:from the original on 18 November 2020
5472:
5156:from the original on 27 February 2021
4858:from the original on 26 February 2021
4796:from the original on 25 February 2021
4772:
4747:
4738:
4591:
4582:
4495:
4446:
4444:
4143:
4141:
4028:
4026:
4024:
4022:
4020:
4018:
4016:
3461:
3430:
3028:
2994:
2973:from the original on 10 November 2020
2940:from the original on 14 February 2021
2830:
2828:
2779:
2777:
2730:The Journal of Clinical Investigation
2470:
2468:
2466:
1993:from the original on 19 December 2020
1959:from the original on 19 December 2020
1806:
1677:
1675:
875:and assist its penetration in cells.
612:mRNA is generated from an engineered
267:The first human clinical trial using
183:Nobel Prize in Physiology or Medicine
135:, have the disadvantage of requiring
64:that would normally be produced by a
16703:Cases, deaths, recoveries by country
16685:
8650:2022 Winter Olympics and Paralympics
8569:2020 Summer Olympics and Paralympics
5927:Knapton, Sarah (20 September 2021).
5893:
5617:
5605:from the original on 22 January 2021
5590:
5505:
5493:from the original on 26 January 2021
5430:from the original on 28 January 2021
5398:from the original on 1 February 2021
5364:from the original on 24 January 2021
5125:from the original on 11 January 2021
4713:
4704:
4692:from the original on 5 February 2021
4679:
4673:
4521:from the original on 1 December 2020
4300:from the original on 26 January 2021
4001:from the original on 30 January 2021
3480:from the original on 14 January 2021
3449:from the original on 2 December 2020
3328:
3292:
2477:Expert Opinion on Biological Therapy
2362:from the original on 13 October 2021
2070:from the original on 9 February 2021
1971:
1890:from the original on 31 January 2021
1856:from the original on 7 December 2020
1830:from the original on 2 December 2020
1794:from the original on 2 December 2020
1788:Department of Health and Social Care
1660:from the original on 6 December 2018
1575:
1573:
1571:
1569:
1567:
1565:
1563:
1561:
1559:
1544:from the original on 11 January 2021
843:Naked mRNA injection means that the
15194:Extracorporeal membrane oxygenation
14095:Chinese Academy of Medical Sciences
13245:protests against Benjamin Netanyahu
5835:
5802:
5581:
4282:
2665:
2347:
2212:
1989:(Press release). 18 December 2020.
1886:(Press release). 11 December 2020.
1684:RNA Vaccines: Methods and Protocols
1630:
127:, and lack of interaction with the
13:
15925:White House COVID-19 Response Team
15919:White House Coronavirus Task Force
15786:Taiwan Centers for Disease Control
13897:Chloroquine and hydroxychloroquine
13564:Non-COVID-19–related health issues
11195:Eastern States Multi-state Council
11122:Trump administration communication
7299:Eradication of infectious diseases
7056:Androvax (androstenedione albumin)
5987:
5632:from the original on 13 March 2021
5024:The Journal of Infectious Diseases
4726:from the original on 24 March 2021
4441:
4138:
4013:
3541:from the original on 14 March 2022
3510:from the original on 16 March 2022
3470:"Pfizer-BioNTech COVID-19 Vaccine"
3007:from the original on 2 August 2021
2825:
2774:
2596:Kallen KJ, Theß A (January 2014).
2463:
1729:Journal of Pharmaceutical Sciences
1672:
1303:
1300:in an attempt to reduce toxicity.
898:Assembly of RNA lipid nanoparticle
448:Moderna is also developing a mRNA
14:
18348:
13497:
7445:Severe acute respiratory syndrome
6889:Respiratory syncytial virus (RSV)
6096:
5823:from the original on 5 April 2022
4827:from the original on 4 April 2021
4760:from the original on 1 April 2021
4604:from the original on 5 March 2021
3310:from the original on 3 March 2021
3063:(Press release). 2 October 2013.
3041:from the original on 18 June 2021
1556:
1355:Nucleoside-modified messenger RNA
1274:
847:of the vaccine is only done in a
669:can be modified to both decrease
205:
193:for their discoveries concerning
143:, do not have such requirements.
18304:
18292:
18280:
15859:Defeat COVID-19 Ad Hoc Committee
15847:Novel Coronavirus Expert Meeting
15769:Department of Health (Hong Kong)
15494:
14727:Democratic Republic of the Congo
14024:Deaths of anti-vaccine advocates
13211:French West Indies social unrest
10869:Saint Vincent and the Grenadines
9286:Tablighi Jamaat COVID-19 hotspot
8278:Democratic Republic of the Congo
8074:Sahrawi Arab Democratic Republic
7451:Middle East respiratory syndrome
7278:Alternative vaccination schedule
6253:Artificial induction of immunity
6103:
5953:
5920:
5887:
5751:
3067:from the original on 2 June 2021
2602:Therapeutic Advances in Vaccines
1265:
1191:body believing itself to be sick
1131:
391:Crimean-Congo haemorrhagic fever
133:Pfizer–BioNTech COVID-19 vaccine
15883:COVID-19 Genomics UK Consortium
15871:Central Epidemic Command Center
15763:Ghana Infectious Disease Centre
13650:investigations into the origins
13341:Moldovan–Romanian collaboration
12800:restaurant industry in the U.S.
11200:Midwest Governors Regional Pact
6156:"RNA vaccines: an introduction"
5908:from the original on 6 May 2021
5538:
5512:Kuchler H (30 September 2020).
5442:
5301:
5217:
5168:
5104:
5011:
4970:
4921:
4870:
4616:
4598:Chemical & Engineering News
4533:
4397:
4356:
4312:
4241:
4198:
3982:
3938:Anand P, Stahel VP (May 2021).
3931:
3779:
3730:
3656:
3603:
3522:
3492:
3373:
3322:
3225:
3182:
3138:
3079:
3053:
2922:
2879:
2717:
2638:
2589:
2554:
2511:
2432:
2378:
2341:
2158:
2133:
2107:
2082:
2005:
1902:
1648:"RNA vaccines: an introduction"
1177:
1067:
960:
765:, leading to interactions with
341:
278:therapeutic cancer mRNA vaccine
239:was shown in 1993 to stimulate
14042:Post-vaccination complications
13351:Respirator diplomacy of Taiwan
11649:Federated States of Micronesia
11180:California government response
10736:Provincial government response
9965:British Indian Ocean Territory
7110:Ovandrotone albumin (Fecundin)
5901:Science Translational Medicine
5593:"The Promise of mRNA Vaccines"
4846:Rowland C (18 February 2021).
4722:. Royal Society of Chemistry.
3989:Goldman B (22 December 2020).
3694:Advanced Drug Delivery Reviews
3610:Bafaloukos, Dimitrios (2023).
2520:European Journal of Immunology
1716:
1399:Advanced Drug Delivery Reviews
262:
1:
16248:(Director-General of the WHO)
15954:SAARC COVID-19 Emergency Fund
13677:Undercounting COVID-19 deaths
13162:Beijing Sitong Bridge protest
12176:References in popular culture
8856:SAARC COVID-19 Emergency Fund
7970:
6646:Group B streptococcal disease
6465:Vaccines for Children Program
5896:"A Malaria Vaccine Candidate"
5559:10.1126/science.370.6520.1022
5144:Rabson M (27 February 2021).
4600:. American Chemical Society.
4267:10.1158/0008-5472.can-10-0699
3437:Roberts M (2 December 2020).
3398:10.1158/1078-0432.CCR-21-0079
3191:Nature Reviews Drug Discovery
3160:10.1016/S0140-6736(17)31665-3
2959:Garade D (10 November 2020).
2681:Nature Reviews Drug Discovery
1586:Nature Reviews Drug Discovery
1370:
1245:to prevent mRNA degradation.
1216:modified nucleoside technique
1172:expanded access authorization
1076:over established traditional
1014:
15811:COVID-19 Immunity Task Force
15355:
14019:Misinformation and hesitancy
13934:Great Barrington Declaration
11804:Australian Capital Territory
11185:New York government response
10891:British Overseas Territories
7423:
5729:10.1517/17425247.2014.901308
5479:Thomas K (22 October 2020).
4649:10.1021/acs.nanolett.8b00432
4507:Cooney E (1 December 2020).
4419:10.1097/CJI.0b013e3181a00068
4294:Immunisation Advisory Centre
4219:10.1586/14760584.2014.957684
3813:10.1371/journal.pcbi.1006857
2900:10.1097/CJI.0b013e31815ce501
2810:10.1016/j.immuni.2005.06.008
2575:10.1016/0264-410x(94)90074-4
1985:Food and Drug Administration
1882:Food and Drug Administration
1520:10.1016/j.nantod.2019.100766
1314:RNA-dependent RNA polymerase
1222:
462:
175:Food and Drug Administration
7:
15732:Wuhan Institute of Virology
12630:Native American communities
11175:state and local governments
8891:Andaman and Nicobar Islands
5994:Dolgin E (September 2021).
5591:Kwon D (25 November 2020).
5326:10.1016/j.ymthe.2017.11.017
5234:10.1007/978-1-4939-6481-9_6
4094:10.1007/978-3-319-42934-2_5
1692:10.1007/978-1-4939-6481-9_1
1460:10.1016/j.ymthe.2019.02.012
1343:
1200:
1168:emergency use authorization
860:Polymer and peptide vectors
700:
376:emergency use authorization
179:emergency use authorization
84:by a co-formulation of the
10:
18353:
16717:WHO situation reports
16053:Awang Bulgiba Awang Mahmud
15990:
15595:Pyongyang General Hospital
15589:Kemayoran Athletes Village
13641:AbC-19 rapid antibody test
13346:Nicaragua–Taiwan relations
13167:healthcare reform protests
12594:U.S. immigration detention
12143:
9840:local lockdown regulations
8863:state government responses
6218:characters and situations.
6025:10.1038/d41586-021-02483-w
5863:10.1038/s41434-020-00204-y
5082:10.1038/d41587-020-00022-y
4877:Lundstrom K (March 2019).
4680:Lowe D (3 February 2021).
4470:10.1186/s12943-021-01311-z
3957:10.1186/s13037-021-00291-9
3872:10.1038/natrevmats.2017.56
3792:PLOS Computational Biology
3755:10.1038/s41541-021-00292-w
3706:10.1016/j.addr.2020.12.006
3580:10.1038/s41591-023-02432-2
3351:10.1038/d41586-020-03626-1
3300:"COVID-19 and Your Health"
3259:10.1038/s41578-021-00358-0
3203:10.1038/d41573-021-00176-7
3108:10.1038/d41586-021-02483-w
1741:10.1016/j.xphs.2020.12.006
1411:10.1016/j.addr.2020.12.008
1365:Timeline of human vaccines
1226:
1136:
1118:untranslated regions (UTR)
964:
787:
761:display antigens on their
751:
481:of a messenger RNA vaccine
466:
302:launched at this time the
200:
18237:
18184:
17715:
17241:
17080:
16861:
16695:
16691:
16680:
16656:
16600:
16425:Hugo López-Gatell Ramírez
16365:Francesco Paolo Figliuolo
16273:
16238:
16231:
16043:
16000:
15996:
15985:
15940:
15795:
15747:
15715:
15708:
15697:
15690:
15636:NHS Nightingale Hospitals
15607:Mega Ligtas COVID Centers
15559:
15521:Central Hospital of Wuhan
15513:
15504:
15500:
15489:
15450:
15367:
15363:
15350:
15290:Small molecule antivirals
15288:
15225:
15177:Drug repurposing research
15167:
15158:
15134:
15103:
15077:
15022:
14901:
14785:
14662:
14651:
14614:
14553:
14456:
14443:Stemirna COVID-19 vaccine
14393:
14372:
14346:
14328:
14321:
14299:
14261:
14181:
14158:
14085:
14067:
14060:
13986:
13977:
13964:Workplace hazard controls
13879:
13685:
13601:
13592:
13507:
13503:
13492:
13441:
13368:
13321:
13071:
13043:
13020:
13011:
12950:
12927:
12920:
12898:Global stock market crash
12888:
12847:
12819:Long-term care facilities
12795:meat industry in the U.S.
12760:
12702:
12679:
12670:
12643:
12602:
12566:
12528:
12497:
12452:
12443:
12362:
12341:
12328:
12319:
12277:
12259:
12250:
12164:
12155:
12151:
12138:
12071:
11936:
11862:
11764:
11629:
11620:
11215:
11190:Texas government response
11160:
11117:
11108:
11045:
11020:
10989:
10959:
10936:
10932:
10889:
10827:Guantanamo Bay Naval Base
10799:
10792:
10671:Newfoundland and Labrador
10597:
10589:Saint Pierre and Miquelon
10571:
10560:
10525:
10487:
10153:
10105:
9984:
9792:
9690:
9681:
9672:
9510:
9349:
9246:
9105:
9096:
8883:
8846:union government response
8791:
8782:
8725:
8716:
8613:
8544:
8537:
8459:
8450:
8301:
8255:
8187:
8084:
8011:
7982:
7978:
7965:
7936:
7795:
7640:
7485:
7435:
7431:
7418:
7394:
7317:
7286:
7225:
7157:
7048:
7020:
6987:
6661:
6492:
6485:
6404:
6332:
6284:
4207:Expert Review of Vaccines
4166:10.1038/s41541-020-0159-8
3944:Patient Safety in Surgery
3573:(6): 1287. 16 June 2023.
3029:Usdin S (19 March 2020).
2489:10.1517/14712598.4.8.1285
2021:MMWR Morb Mortal Wkly Rep
1918:MMWR Morb Mortal Wkly Rep
1160:
890:Lipid nanoparticle vector
17113:vaccinations by province
16847:Hospital beds by country
16317:Kenneth Chuang Yin-ching
15895:Joint Biosecurity Centre
15662:Yorkshire and the Humber
15551:Wuhan Jinyintan Hospital
14576:DelNS1-2019-nCoV-RBD-OPT
14338:COVI-VAC (United States)
13949:Public health mitigation
13636:UK Rapid Test Consortium
13584:Unproven medical methods
12300:exam grading controversy
11699:Northern Mariana Islands
11469:Northern Mariana Islands
10919:Turks and Caicos Islands
9187:circuit breaker response
8268:Central African Republic
6641:Clostridioides difficile
4748:Sealy A (2 April 2021).
4714:King A (23 March 2021).
4592:Cross R (6 March 2021).
4407:Journal of Immunotherapy
3851:Nature Reviews Materials
3631:10.3390/vaccines11030636
3386:Clinical Cancer Research
3238:Nature Reviews Materials
2995:Sonne P (30 July 2020).
2888:Journal of Immunotherapy
2614:10.1177/2051013613508729
2034:10.15585/mmwr.mm695152e1
1122:guanine-cytosine content
1114:open reading frame (ORF)
687:guanine-cytosine content
673:and increase the mRNA's
671:innate immune activation
380:Moderna COVID-19 vaccine
78:adaptive immune response
16377:Henrique Gouveia e Melo
15907:COVID-19 Advisory Board
15817:COVID-19 Supply Council
15675:Dragon's Heart Hospital
15235:Bamlanivimab/etesevimab
14606:Vaxart COVID-19 vaccine
13323:International relations
13228:Idar-Oberstein shooting
12790:meat industry in Canada
12482:foster care in the U.S.
11814:Cocos (Keeling) Islands
8936:Tablighi Jamaat hotspot
8811:migrant workers' crisis
8767:Tablighi Jamaat hotspot
6899:Tick-borne encephalitis
6164:University of Cambridge
5894:Lowe D (1 March 2021).
5777:10.3390/vaccines7040122
4821:The Wall Street Journal
3504:investors.modernatx.com
2854:10.3390/vaccines9020097
2456:9 December 2021 at the
2445:14 October 2021 at the
2327:10.1126/science.1690918
2257:10.1073/pnas.86.16.6077
1653:University of Cambridge
1646:PHG Foundation (2019).
727:electrostatic repulsion
618:RNA polymerase promoter
590:
563:. Class I and class II
477:An illustration of the
288:were reported in 2008.
17759:Bosnia and Herzegovina
16628:Joseph Ashitey Hammond
15275:Tixagevimab/cilgavimab
15199:Open-source ventilator
14914:Bosnia and Herzegovina
13611:Death rates by country
13476:Science and technology
12510:Indian migrant workers
10904:British Virgin Islands
10283:North Rhine-Westphalia
10118:Bosnia and Herzegovina
9845:first tier regulations
9281:movement control order
9276:Aid and relief efforts
7309:List of vaccine topics
6309:Mathematical modelling
5717:Expert Opin Drug Deliv
5628:(Reality Check). BBC.
5181:Nucleic Acids Research
4996:10.1006/viro.2000.0635
2532:10.1002/eji.1830230749
1931:10.15585/mmwr.mm6950e2
1298:N1-Methylpseudouridine
1284:
1029:
899:
853:intradermal injections
772:The simplest way that
710:
677:in the host cell. The
644:5'-untranslated region
600:
487:adaptive immune system
482:
215:
109:
30:
18337:Nucleic acid vaccines
16998:São Tomé and Príncipe
15255:Casirivimab/imdevimab
15227:Monoclonal antibodies
13757:Exposure Notification
13742:COVID Tracker Ireland
13710:Coronavirus Australia
13201:Yellow vests protests
12635:Xenophobia and racism
10960:Caribbean Netherlands
10859:Saint Kitts and Nevis
10676:Northwest Territories
9960:Akrotiri and Dhekelia
9384:community quarantines
8293:São Tomé and Príncipe
8283:Republic of the Congo
7304:Vaccinate Your Family
6755:Japanese encephalitis
5967:. 20 September 2021.
5658:Microbiology Spectrum
5036:10.1093/infdis/jir349
5030:(Suppl 3): S1075–81.
4896:10.3390/genes10030189
4558:10.4155/tde-2016-0006
4382:10.4161/rna.8.4.15394
4334:10.1038/sj.gt.3302964
4296:. 22 September 2016.
3997:. Stanford Medicine.
2787:, Buckstein M, Ni H,
2348:May M (31 May 2021).
2313:(4949 Pt 1): 1465–8.
1282:
1255:reverse transcriptase
1227:Further information:
1027:
965:Further information:
951:U.S. half-dollar coin
897:
708:
679:nucleic acid sequence
598:
529:synthetically created
512:(weakened) virus, an
476:
467:Further information:
411:Marburg virus disease
218:The first successful
213:
107:
24:
17671:United Arab Emirates
17332:confirmed per capita
16479:Noor Hisham Abdullah
16293:Catherine Calderwood
15578:Hospital El Salvador
15546:Xinjia Express Hotel
15541:Leishenshan Hospital
15536:Huoshenshan Hospital
14888:United Arab Emirates
14616:Virus-like particles
14437:Sanofi–Translate Bio
14301:Virus-like particles
14036:Operation Warp Speed
13954:Safe Hands Challenge
13929:Flattening the curve
13842:Test, Trace, Protect
13388:Flattening the curve
12942:Knowledge's response
12625:Disability community
12574:Abortion in the U.S.
12370:Association football
11912:Traffic light system
11152:2021 hospital crisis
10748:Prince Edward Island
10061:government responses
9955:Overseas territories
9655:United Arab Emirates
8603:respirator diplomacy
7187:John Franklin Enders
5267:Nature Biotechnology
5074:Nature Biotechnology
4946:10.1089/hum.2014.100
4546:Therapeutic Delivery
4290:"Vaccine components"
4052:10.3390/ijms21186582
3306:. 11 February 2020.
2936:. 13 November 2020.
2404:10.3390/ijms21186582
2184:10.3390/ijms21186582
1598:10.1038/nrd.2017.243
1209:Physician-scientist
1102:Modified nucleosides
1020:Traditional vaccines
967:Viral vector vaccine
839:Naked mRNA injection
811:Different routes of
282:modified nucleosides
195:modified nucleosides
154:. In December 2020,
56:-encoding mRNA into
17613:vaccinations charts
17554:areas of quarantine
16353:Francisco Duque III
16305:Anutin Charnvirakul
15583:SevenHills Hospital
15572:Garran Surge Centre
14540:West China Hospital
13917:Anti-mask sentiment
13891:Corsi–Rosenthal Box
13537:Skin manifestations
12870:Global supply chain
12694:Travel restrictions
12684:Charitable activity
12620:African communities
11902:government response
11557:U.S. Virgin Islands
11205:Western States Pact
11033:U.S. Virgin Islands
10874:Trinidad and Tobago
10807:Antigua and Barbuda
10470:government response
10453:Community of Madrid
10389:government response
10288:government response
9745:government response
9493:Zamboanga Peninsula
9403:testing controversy
9379:government response
9236:government response
9140:social restrictions
8416:government response
8364:government response
6373:Virus-like particle
6297:Vaccine ingredients
6066:Nat Rev Drug Discov
6017:2021Natur.597..318D
5934:The Daily Telegraph
5460:on 16 November 2020
5279:10.1038/nbt0698-562
4852:The Washington Post
4641:2018NanoL..18.2148P
3863:2017NatRM...217056H
3804:2019PLSCB..15E6857B
3343:2021Natur.589...16B
3250:2021NatRM...6.1078H
3100:2021Natur.597..318D
3001:The Washington Post
2319:1990Sci...247.1465W
2248:1989PNAS...86.6077M
1790:. 2 December 2020.
1310:open reading frames
1187:autoimmune response
904:lipid nanoparticles
733:in skin and blood.
663:regulatory elements
573:present the antigen
479:mechanism of action
399:Ebola virus disease
171:medicines regulator
117:autoimmune response
90:lipid nanoparticles
18197:by state/territory
18157:vaccinations chart
18028:by federal subject
17898:vaccinations chart
17635:vaccination charts
17581:by federal subject
17559:vaccinations chart
17154:Dominican Republic
16433:(Northern Ireland)
16258:Maria Van Kerkhove
15531:Fangcang hospitals
15473:Variant of concern
14281:Oxford–AstraZeneca
13662:Rapid antigen test
13626:Operation Moonshot
13279:Wellington protest
13096:Convoy to Canberra
13025:National responses
12903:COVID-19 recession
12505:Healthcare workers
12119:Theodore Roosevelt
11829:Northern Territory
11170:federal government
10990:French West Indies
10839:Dominican Republic
10054:July–December 2020
9933:Crown Dependencies
9757:Operation Rescript
9728:July–December 2022
9718:July–December 2021
9708:July–December 2020
9498:Overseas Filipinos
7344:Never to phase III
7143:Hexavalent vaccine
6957:Epstein–Barr virus
6852:Oxford–AstraZeneca
6545:NmVac4-A/C/Y/W-135
6189:The New York Times
6113:has a profile for
5651:Skalka AM (2014).
5426:. ModernaTX, Inc.
5386:Simmons-Duffin S.
5193:10.1093/nar/gkr695
4934:Human Gene Therapy
3154:(10101): 1511–20.
1327:started in 2021 a
1289:open reading frame
1285:
1030:
900:
711:
652:open reading frame
616:DNA, which has an
601:
483:
216:
166:(MHRA) became the
110:
31:
18268:
18267:
18264:
18263:
18260:
18259:
18244:Cruise ships
17893:statistics charts
17700:statistics charts
16676:
16675:
16672:
16671:
16638:Captain Tom Moore
16596:
16595:
16539:Þórólfur Guðnason
16487:(Northern Cyprus)
16473:Nguyễn Thanh Long
16347:Christian Drosten
16343:(the Netherlands)
16287:Ashley Bloomfield
16083:Christian Drosten
16068:Kizzmekia Corbett
15981:
15980:
15977:
15976:
15973:
15972:
15969:
15968:
15901:Vaccine Taskforce
15686:
15685:
15669:NHS Louisa Jordan
15485:
15484:
15481:
15480:
15468:Lineage B.1.640.2
15346:
15345:
15342:
15341:
15338:
15337:
15319:Co-packaged
15154:
15153:
15150:
15149:
14742:Equatorial Guinea
14647:
14646:
14317:
14316:
14052:Vaccine passports
13999:Clinical research
13959:Social distancing
13939:International aid
13875:
13874:
13488:
13487:
13484:
13483:
13408:Social distancing
13364:
13363:
13356:Vaccine diplomacy
13007:
13006:
12916:
12915:
12890:Financial markets
12780:Cannabis industry
12666:
12665:
12584:Domestic violence
12515:Great Resignation
12439:
12438:
12435:
12434:
12333:Bio-secure bubble
12315:
12314:
12233:programs affected
12168:cultural heritage
12134:
12133:
12130:
12129:
12111:Charles de Gaulle
11932:
11931:
11924:managed isolation
11854:Western Australia
11756:Wallis and Futuna
11616:
11615:
11612:
11611:
11041:
11040:
10985:
10984:
10634:military response
10556:
10555:
10049:January–June 2020
9980:
9979:
9723:January–June 2022
9713:January–June 2021
9703:January–June 2020
9668:
9667:
9506:
9505:
9478:Northern Mindanao
9092:
9091:
9088:
9087:
8963:Jammu and Kashmir
8901:Arunachal Pradesh
8712:
8711:
8446:
8445:
8324:Equatorial Guinea
7961:
7960:
7957:
7956:
7457:Crimson Contagion
7388:COVID-19 pandemic
7354:
7353:
7266:Vaccines and SIDS
7153:
7152:
6927:Hepatitis A and B
6903:Varicella zoster
6365:Subunit/component
6178:. 4 January 2022.
6119:
5314:Molecular Therapy
5243:978-1-4939-6479-6
4103:978-3-319-42932-8
3907:10.4161/rna.22269
2027:(5152): 1653–56.
1786:(Press release).
1701:978-1-4939-6479-6
1233:vaccine hesitancy
1038:cellular immunity
917:Principally, the
865:Cationic polymers
695:synonymous codons
431:Rift Valley fever
387:Chikungunya virus
356:COVID-19 vaccines
348:COVID-19 pandemic
336:Chikungunya virus
152:COVID-19 vaccines
137:ultracold storage
105:
18344:
18309:
18308:
18297:
18296:
18285:
18284:
18283:
18276:
18249:Diamond Princess
18224:Papua New Guinea
18209:French Polynesia
16693:
16692:
16686:Data (templates)
16682:
16681:
16577:(United Kingdom)
16545:Sotiris Tsiodras
16521:Łukasz Szumowski
16407:Jeong Eun-kyeong
16385:(United Kingdom)
16299:Chang Shan-chwen
16236:
16235:
15998:
15997:
15987:
15986:
15903:(United Kingdom)
15897:(United Kingdom)
15891:(United Kingdom)
15885:(United Kingdom)
15825:(European Union)
15740:(United Kingdom)
15738:Independent SAGE
15720:National Cabinet
15713:
15712:
15695:
15694:
15638:(England)
15511:
15510:
15502:
15501:
15491:
15490:
15365:
15364:
15352:
15351:
15216:Solidarity trial
15172:Drug development
15165:
15164:
14660:
14659:
14326:
14325:
14198:(Bio E COVID-19)
14115:CoviVac (Russia)
14065:
14064:
13984:
13983:
13867:Zoe Health Study
13802:NZ Pass Verifier
13767:Healthy Together
13599:
13598:
13532:Endemic COVID-19
13505:
13504:
13494:
13493:
13045:Political impact
13018:
13017:
12976:By country
12925:
12924:
12848:Supply and trade
12829:Public transport
12677:
12676:
12472:COVID-19 parties
12450:
12449:
12326:
12325:
12264:Female education
12257:
12256:
12203:Fashion industry
12162:
12161:
12153:
12152:
12140:
12139:
12090:Diamond Princess
12016:Falkland Islands
11809:Christmas Island
11721:Pitcairn Islands
11709:Papua New Guinea
11679:Marshall Islands
11659:French Polynesia
11627:
11626:
11582:Washington, D.C.
11115:
11114:
11021:US insular areas
11007:Saint Barthélemy
10934:
10933:
10797:
10796:
10656:British Columbia
10569:
10568:
10475:Operation Gloria
10066:political impact
9910:timeline
9883:timeline
9856:timeline
9852:Northern Ireland
9804:timeline
9688:
9687:
9679:
9678:
9584:Kurdistan Region
9166:timeline
9129:timeline
9103:
9102:
8958:Himachal Pradesh
8820:timeline
8789:
8788:
8723:
8722:
8542:
8541:
8457:
8456:
8009:
8008:
7980:
7979:
7967:
7966:
7433:
7432:
7420:
7419:
7381:
7374:
7367:
7358:
7357:
7245:MMR autism fraud
7192:Maurice Hilleman
7177:Hilary Koprowski
6490:
6489:
6246:
6239:
6232:
6223:
6222:
6198:
6192:
6179:
6167:
6151:
6149:
6147:
6138:. Archived from
6117:
6107:
6106:
6092:
6082:
6059:(October 2014).
6044:
6000:
5981:
5980:
5978:
5976:
5957:
5951:
5950:
5948:
5946:
5924:
5918:
5917:
5915:
5913:
5891:
5885:
5884:
5874:
5857:(3–4): 117–129.
5842:
5833:
5832:
5830:
5828:
5809:
5800:
5799:
5789:
5779:
5755:
5749:
5748:
5712:
5703:
5702:
5692:
5648:
5642:
5641:
5639:
5637:
5621:
5615:
5614:
5612:
5610:
5588:
5579:
5578:
5542:
5536:
5535:
5533:
5531:
5509:
5503:
5502:
5500:
5498:
5476:
5470:
5469:
5467:
5465:
5456:. Archived from
5446:
5440:
5439:
5437:
5435:
5425:
5417:
5408:
5407:
5405:
5403:
5383:
5374:
5373:
5371:
5369:
5354:
5348:
5347:
5337:
5305:
5299:
5298:
5262:
5256:
5255:
5221:
5215:
5214:
5204:
5172:
5166:
5165:
5163:
5161:
5141:
5135:
5134:
5132:
5130:
5118:Business Insider
5108:
5102:
5101:
5069:
5058:
5057:
5047:
5015:
5009:
5008:
4998:
4974:
4968:
4967:
4957:
4925:
4919:
4918:
4908:
4898:
4874:
4868:
4867:
4865:
4863:
4843:
4837:
4836:
4834:
4832:
4812:
4806:
4805:
4803:
4801:
4781:
4770:
4769:
4767:
4765:
4745:
4736:
4735:
4733:
4731:
4711:
4702:
4701:
4699:
4697:
4677:
4671:
4670:
4660:
4620:
4614:
4613:
4611:
4609:
4589:
4580:
4579:
4569:
4537:
4531:
4530:
4528:
4526:
4504:
4493:
4492:
4482:
4472:
4457:Molecular Cancer
4448:
4439:
4438:
4401:
4395:
4394:
4384:
4360:
4354:
4353:
4316:
4310:
4309:
4307:
4305:
4286:
4280:
4279:
4269:
4245:
4239:
4238:
4202:
4196:
4195:
4185:
4145:
4136:
4135:
4129:
4125:
4123:
4115:
4081:
4075:
4074:
4064:
4054:
4030:
4011:
4010:
4008:
4006:
3986:
3980:
3979:
3969:
3959:
3935:
3929:
3928:
3918:
3886:
3877:
3876:
3874:
3842:
3836:
3835:
3825:
3815:
3783:
3777:
3776:
3766:
3734:
3728:
3727:
3717:
3685:
3676:
3675:
3673:
3671:
3660:
3654:
3653:
3643:
3633:
3607:
3601:
3600:
3582:
3557:
3551:
3550:
3548:
3546:
3526:
3520:
3519:
3517:
3515:
3496:
3490:
3489:
3487:
3485:
3465:
3459:
3458:
3456:
3454:
3434:
3428:
3427:
3417:
3377:
3371:
3370:
3326:
3320:
3319:
3317:
3315:
3296:
3290:
3289:
3279:
3261:
3229:
3223:
3222:
3186:
3180:
3179:
3142:
3136:
3135:
3094:(7876): 318–24.
3083:
3077:
3076:
3074:
3072:
3057:
3051:
3050:
3048:
3046:
3026:
3017:
3016:
3014:
3012:
2992:
2983:
2982:
2980:
2978:
2956:
2950:
2949:
2947:
2945:
2926:
2920:
2919:
2883:
2877:
2876:
2866:
2856:
2832:
2823:
2822:
2812:
2781:
2772:
2771:
2761:
2742:10.1172/JCI14364
2721:
2715:
2714:
2696:
2672:
2663:
2662:
2642:
2636:
2635:
2625:
2593:
2587:
2586:
2558:
2552:
2551:
2515:
2509:
2508:
2472:
2461:
2436:
2430:
2429:
2416:
2406:
2382:
2376:
2375:
2369:
2367:
2345:
2339:
2338:
2291:
2280:
2279:
2269:
2259:
2216:
2210:
2209:
2196:
2186:
2162:
2156:
2155:
2153:
2151:
2137:
2131:
2130:
2128:
2126:
2121:. 2 October 2023
2111:
2105:
2104:
2102:
2100:
2086:
2080:
2079:
2077:
2075:
2069:
2046:
2036:
2018:
2009:
2003:
2002:
2000:
1998:
1975:
1969:
1968:
1966:
1964:
1958:
1943:
1933:
1915:
1906:
1900:
1899:
1897:
1895:
1872:
1866:
1865:
1863:
1861:
1846:
1840:
1839:
1837:
1835:
1813:
1804:
1803:
1801:
1799:
1780:
1771:
1770:
1760:
1720:
1714:
1713:
1679:
1670:
1669:
1667:
1665:
1643:
1628:
1627:
1617:
1577:
1554:
1553:
1551:
1549:
1531:
1499:
1482:
1481:
1471:
1439:
1433:
1432:
1422:
1390:
1360:RNA therapeutics
1042:humoral immunity
940:lymphatic system
748:) the organism.
636:eukaryotic cells
177:(FDA) issued an
148:RNA therapeutics
125:humoral immunity
106:
88:encapsulated in
18352:
18351:
18347:
18346:
18345:
18343:
18342:
18341:
18317:
18316:
18315:
18303:
18291:
18281:
18279:
18271:
18269:
18256:
18233:
18229:Solomon Islands
18180:
17962:North Macedonia
17711:
17237:
17076:
16857:
16687:
16668:
16652:
16592:
16589:(United States)
16569:Vlad Voiculescu
16557:Víðir Reynisson
16431:Michael McBride
16361:(United States)
16341:Jaap van Dissel
16329:Fabrizio Curcio
16323:Victor Costache
16311:Chen Shih-chung
16269:
16264:Michael J. Ryan
16227:
16073:Andrea Crisanti
16058:Roberto Burioni
16039:
16015:Corona Rintawan
16002:
15992:
15965:
15962:(United States)
15936:
15927:(United States)
15921:(United States)
15915:(United States)
15909:(United States)
15797:
15791:
15759:(African Union)
15749:
15743:
15704:
15682:
15555:
15507:medical clinics
15506:
15496:
15477:
15463:Lineage B.1.617
15446:
15359:
15334:
15284:
15221:
15204:PANORAMIC trial
15146:
15130:
15099:
15073:
15018:
14897:
14781:
14654:
14643:
14610:
14549:
14452:
14389:
14368:
14354:AG0302-COVID‑19
14342:
14313:
14295:
14257:
14177:
14173:Pfizer–BioNTech
14154:
14110:COVIran Barekat
14081:
14056:
13973:
13871:
13797:NZ COVID Tracer
13715:Corona-Warn-App
13681:
13655:lab leak theory
13631:Test to Release
13616:Disease testing
13594:
13588:
13499:
13480:
13437:
13360:
13317:
13311:Open the States
13067:
13039:
13003:
12946:
12912:
12884:
12843:
12756:
12698:
12662:
12653:Catholic Church
12639:
12598:
12562:
12524:
12493:
12489:Pandemic baking
12445:
12431:
12358:
12337:
12311:
12273:
12246:
12213:Performing arts
12167:
12157:
12147:
12126:
12067:
11939:
11928:
11897:economic impact
11858:
11839:South Australia
11819:New South Wales
11760:
11731:Solomon Islands
11608:
11211:
11156:
11147:economic impact
11126:timeline
11104:
11046:Central America
11037:
11016:
10981:
10955:
10928:
10885:
10788:
10695:timeline
10639:Atlantic Bubble
10610:economic impact
10593:
10563:
10552:
10521:
10483:
10330:economic impact
10309:timeline
10195:Northern Cyprus
10149:
10133:North Macedonia
10106:Western Balkans
10101:
10045:timeline
9996:timeline
9976:
9788:
9699:timeline
9664:
9545:Northern Cyprus
9502:
9488:Western Visayas
9458:Eastern Visayas
9443:Central Visayas
9358:timeline
9345:
9290:timeline
9242:
9084:
8879:
8796:economic impact
8778:
8708:
8609:
8533:
8481:timeline
8442:
8350:August–December
8338:timeline
8297:
8251:
8183:
8080:
7997:
7974:
7953:
7932:
7791:
7636:
7481:
7472:Exercise Cygnus
7427:
7414:
7390:
7385:
7355:
7350:
7349:
7334:Clinical trials
7313:
7282:
7221:
7197:Stanley Plotkin
7159:
7149:
7061:Cancer vaccines
7044:
7038:Schistosomiasis
7016:
7010:Trypanosomiasis
6983:
6947:Cytomegalovirus
6857:Pfizer–BioNTech
6657:
6481:
6430:Vaccine wastage
6400:
6328:
6280:
6250:
6196:
6170:
6154:
6145:
6143:
6142:on 4 April 2020
6128:
6125:
6124:
6123:
6108:
6104:
6099:
6080:10.1038/nrd4278
5998:
5990:
5988:Further reading
5985:
5984:
5974:
5972:
5959:
5958:
5954:
5944:
5942:
5925:
5921:
5911:
5909:
5892:
5888:
5843:
5836:
5826:
5824:
5817:www.science.org
5811:
5810:
5803:
5756:
5752:
5713:
5706:
5681:
5649:
5645:
5635:
5633:
5622:
5618:
5608:
5606:
5589:
5582:
5543:
5539:
5529:
5527:
5519:Financial Times
5510:
5506:
5496:
5494:
5477:
5473:
5463:
5461:
5448:
5447:
5443:
5433:
5431:
5423:
5419:
5418:
5411:
5401:
5399:
5384:
5377:
5367:
5365:
5356:
5355:
5351:
5306:
5302:
5263:
5259:
5244:
5222:
5218:
5173:
5169:
5159:
5157:
5142:
5138:
5128:
5126:
5109:
5105:
5070:
5061:
5016:
5012:
4975:
4971:
4926:
4922:
4875:
4871:
4861:
4859:
4844:
4840:
4830:
4828:
4813:
4809:
4799:
4797:
4782:
4773:
4763:
4761:
4746:
4739:
4729:
4727:
4720:Chemistry World
4712:
4705:
4695:
4693:
4678:
4674:
4621:
4617:
4607:
4605:
4590:
4583:
4538:
4534:
4524:
4522:
4505:
4496:
4449:
4442:
4402:
4398:
4361:
4357:
4328:(15): 1175–80.
4317:
4313:
4303:
4301:
4288:
4287:
4283:
4260:(22): 9031–40.
4254:Cancer Research
4246:
4242:
4203:
4199:
4146:
4139:
4127:
4126:
4117:
4116:
4104:
4082:
4078:
4031:
4014:
4004:
4002:
3987:
3983:
3936:
3932:
3901:(11): 1319–30.
3887:
3880:
3843:
3839:
3798:(7): e1006857.
3784:
3780:
3735:
3731:
3686:
3679:
3669:
3667:
3666:. 25 April 2024
3662:
3661:
3657:
3608:
3604:
3566:Nature Medicine
3559:
3558:
3554:
3544:
3542:
3527:
3523:
3513:
3511:
3498:
3497:
3493:
3483:
3481:
3466:
3462:
3452:
3450:
3435:
3431:
3378:
3374:
3337:(7840): 16–18.
3327:
3323:
3313:
3311:
3298:
3297:
3293:
3244:(12): 1078–94.
3230:
3226:
3187:
3183:
3143:
3139:
3084:
3080:
3070:
3068:
3059:
3058:
3054:
3044:
3042:
3027:
3020:
3010:
3008:
2993:
2986:
2976:
2974:
2957:
2953:
2943:
2941:
2928:
2927:
2923:
2884:
2880:
2833:
2826:
2791:(August 2005).
2782:
2775:
2722:
2718:
2694:10.1038/nrd4278
2673:
2666:
2653:(7): 1397–400.
2647:Cancer Research
2643:
2639:
2594:
2590:
2569:(16): 1510–14.
2559:
2555:
2516:
2512:
2473:
2464:
2458:Wayback Machine
2447:Wayback Machine
2437:
2433:
2383:
2379:
2365:
2363:
2346:
2342:
2292:
2283:
2242:(16): 6077–81.
2230:(August 1989).
2217:
2213:
2163:
2159:
2149:
2147:
2139:
2138:
2134:
2124:
2122:
2113:
2112:
2108:
2098:
2096:
2088:
2087:
2083:
2073:
2071:
2067:
2016:
2010:
2006:
1996:
1994:
1977:
1976:
1972:
1962:
1960:
1956:
1924:(50): 1922–24.
1913:
1907:
1903:
1893:
1891:
1874:
1873:
1869:
1859:
1857:
1848:
1847:
1843:
1833:
1831:
1814:
1807:
1797:
1795:
1782:
1781:
1774:
1735:(3): 997–1001.
1721:
1717:
1702:
1680:
1673:
1663:
1661:
1644:
1631:
1578:
1557:
1547:
1545:
1529:1854/LU-8628303
1500:
1485:
1440:
1436:
1391:
1378:
1373:
1346:
1333:booster vaccine
1321:malaria vaccine
1306:
1304:Self-amplifying
1277:
1268:
1235:
1225:
1203:
1180:
1163:
1139:
1134:
1110:immune response
1070:
1062:fill and finish
1022:
1017:
969:
963:
938:or through the
892:
862:
849:buffer solution
841:
792:
782:electroporation
759:Dendritic cells
756:
703:
656:3'-poly(A) tail
593:
533:dendritic cells
471:
465:
344:
332:cytomegalovirus
274:dendritic cells
265:
253:cellular immune
208:
203:
185:was awarded to
156:Pfizer–BioNTech
141:Moderna vaccine
95:
17:
16:Type of vaccine
12:
11:
5:
18350:
18340:
18339:
18334:
18329:
18314:
18313:
18301:
18289:
18266:
18265:
18262:
18261:
18258:
18257:
18255:
18254:
18253:
18252:
18241:
18239:
18235:
18234:
18232:
18231:
18226:
18221:
18216:
18211:
18206:
18201:
18200:
18199:
18188:
18186:
18182:
18181:
18179:
18178:
18173:
18172:
18171:
18170:
18169:
18164:
18154:
18149:
18148:
18147:
18142:
18136:Scotland
18132:United Kingdom
18129:
18124:
18123:
18122:
18112:
18111:
18110:
18100:
18099:
18098:
18088:
18087:
18086:
18076:
18075:
18074:
18064:
18063:
18062:
18057:
18047:
18042:
18037:
18036:
18035:
18030:
18025:
18015:
18010:
18005:
18004:
18003:
17993:
17992:
17991:
17989:by voivodeship
17986:
17976:
17975:
17974:
17964:
17959:
17954:
17949:
17944:
17939:
17934:
17929:
17928:
17927:
17917:
17912:
17907:
17902:
17901:
17900:
17895:
17890:
17880:
17879:
17878:
17868:
17867:
17866:
17856:
17851:
17846:
17845:
17844:
17834:
17833:
17832:
17822:
17817:
17816:
17815:
17805:
17804:
17803:
17798:
17788:
17786:Czech Republic
17783:
17778:
17773:
17772:
17771:
17761:
17756:
17755:
17754:
17744:
17739:
17738:
17737:
17727:
17721:
17719:
17713:
17712:
17710:
17709:
17704:
17703:
17702:
17692:
17691:
17690:
17680:
17679:
17678:
17668:
17667:
17666:
17656:
17655:
17654:
17644:
17639:
17638:
17637:
17627:
17622:
17617:
17616:
17615:
17610:
17600:
17595:
17590:
17589:
17588:
17583:
17578:
17568:
17563:
17562:
17561:
17556:
17551:
17541:
17540:
17539:
17529:
17528:
17527:
17517:
17516:
17515:
17505:
17504:
17503:
17498:
17488:
17487:
17486:
17481:
17471:
17466:
17461:
17456:
17455:
17454:
17444:
17439:
17434:
17433:
17432:
17422:
17421:
17420:
17410:
17405:
17404:
17403:
17393:
17392:
17391:
17381:
17376:
17371:
17366:
17361:
17356:
17355:
17354:
17349:
17344:
17339:
17334:
17329:
17319:
17318:
17317:
17312:
17302:
17297:
17296:
17295:
17285:
17284:
17283:
17273:
17268:
17263:
17262:
17261:
17251:
17245:
17243:
17239:
17238:
17236:
17235:
17230:
17225:
17224:
17223:
17213:
17208:
17203:
17198:
17193:
17192:
17191:
17181:
17176:
17171:
17166:
17161:
17156:
17151:
17146:
17145:
17144:
17134:
17129:
17128:
17127:
17117:
17116:
17115:
17110:
17100:
17095:
17090:
17084:
17082:
17078:
17077:
17075:
17074:
17073:
17072:
17062:
17057:
17052:
17047:
17042:
17037:
17032:
17027:
17026:
17025:
17015:
17010:
17005:
17000:
16995:
16994:
16993:
16983:
16978:
16973:
16968:
16963:
16958:
16953:
16948:
16943:
16938:
16933:
16932:
16931:
16921:
16916:
16911:
16906:
16901:
16896:
16891:
16886:
16881:
16876:
16871:
16865:
16863:
16859:
16858:
16856:
16854:
16849:
16844:
16843:
16842:
16832:
16831:
16830:
16825:
16824:
16823:
16818:
16813:
16808:
16803:
16798:
16793:
16788:
16783:
16778:
16773:
16768:
16766:September 2020
16763:
16758:
16753:
16748:
16743:
16738:
16733:
16728:
16715:
16710:
16705:
16699:
16697:
16689:
16688:
16678:
16677:
16674:
16673:
16670:
16669:
16667:
16666:
16660:
16658:
16654:
16653:
16651:
16650:
16645:
16640:
16635:
16630:
16625:
16620:
16615:
16610:
16604:
16602:
16598:
16597:
16594:
16593:
16591:
16590:
16584:
16578:
16572:
16566:
16563:Carla Vizzotti
16560:
16554:
16548:
16542:
16536:
16533:Anders Tegnell
16530:
16524:
16518:
16512:
16506:
16503:Fernando Simón
16500:
16497:Jérôme Salomon
16494:
16491:Daniel Salinas
16488:
16482:
16476:
16470:
16464:
16458:
16452:
16446:
16445:(South Africa)
16440:
16434:
16428:
16422:
16416:
16413:Fahrettin Koca
16410:
16404:
16398:
16392:
16386:
16380:
16374:
16368:
16362:
16356:
16350:
16344:
16338:
16332:
16326:
16320:
16314:
16308:
16302:
16296:
16290:
16284:
16281:Frank Atherton
16277:
16275:
16271:
16270:
16268:
16267:
16261:
16255:
16249:
16246:Tedros Adhanom
16242:
16240:
16233:
16229:
16228:
16226:
16225:
16220:
16218:Zhang Yongzhen
16215:
16210:
16205:
16203:Yuen Kwok-yung
16200:
16195:
16190:
16185:
16180:
16178:Mike Tildesley
16175:
16170:
16165:
16160:
16158:Allison McGeer
16155:
16150:
16145:
16140:
16135:
16130:
16125:
16123:Katalin Karikó
16120:
16115:
16110:
16105:
16100:
16095:
16090:
16085:
16080:
16075:
16070:
16065:
16060:
16055:
16049:
16047:
16041:
16040:
16038:
16037:
16032:
16027:
16022:
16017:
16012:
16006:
16004:
15994:
15993:
15983:
15982:
15979:
15978:
15975:
15974:
15971:
15970:
15967:
15966:
15964:
15963:
15957:
15951:
15944:
15942:
15938:
15937:
15935:
15934:
15928:
15922:
15916:
15910:
15904:
15898:
15892:
15886:
15880:
15874:
15868:
15862:
15856:
15850:
15844:
15838:
15832:
15826:
15820:
15814:
15808:
15801:
15799:
15793:
15792:
15790:
15789:
15783:
15782:(South Africa)
15777:
15771:
15766:
15760:
15753:
15751:
15745:
15744:
15742:
15741:
15735:
15729:
15726:ScienceUpFirst
15723:
15716:
15710:
15706:
15705:
15703:
15701:
15699:
15692:
15688:
15687:
15684:
15683:
15681:
15680:
15679:
15678:
15672:
15666:
15665:
15664:
15659:
15654:
15649:
15644:
15628:
15622:
15616:
15610:
15604:
15598:
15592:
15586:
15580:
15575:
15569:
15567:Hospital ships
15563:
15561:
15557:
15556:
15554:
15553:
15548:
15543:
15538:
15533:
15528:
15523:
15517:
15515:
15514:Mainland China
15508:
15498:
15497:
15487:
15486:
15483:
15482:
15479:
15478:
15476:
15475:
15470:
15465:
15460:
15454:
15452:
15448:
15447:
15445:
15444:
15443:
15442:
15432:
15427:
15422:
15417:
15412:
15407:
15402:
15397:
15392:
15387:
15382:
15377:
15371:
15369:
15361:
15360:
15348:
15347:
15344:
15343:
15340:
15339:
15336:
15335:
15333:
15332:
15331:
15330:
15325:
15317:
15316:
15315:
15310:
15305:
15298:Broad-spectrum
15294:
15292:
15286:
15285:
15283:
15282:
15277:
15272:
15267:
15262:
15257:
15252:
15247:
15246:
15245:
15242:
15231:
15229:
15223:
15222:
15220:
15219:
15213:
15210:RECOVERY Trial
15207:
15201:
15196:
15191:
15190:
15189:
15184:
15174:
15168:
15162:
15156:
15155:
15152:
15151:
15148:
15147:
15145:
15144:
15138:
15136:
15132:
15131:
15129:
15128:
15123:
15118:
15113:
15107:
15105:
15101:
15100:
15098:
15097:
15092:
15087:
15081:
15079:
15075:
15074:
15072:
15071:
15070:
15069:
15059:
15054:
15049:
15044:
15043:
15042:
15037:
15026:
15024:
15020:
15019:
15017:
15016:
15014:United Kingdom
15011:
15006:
15001:
14996:
14991:
14986:
14981:
14976:
14971:
14966:
14961:
14956:
14951:
14946:
14941:
14936:
14931:
14926:
14921:
14916:
14911:
14905:
14903:
14899:
14898:
14896:
14895:
14890:
14885:
14880:
14875:
14870:
14865:
14860:
14855:
14850:
14845:
14840:
14835:
14830:
14825:
14820:
14815:
14810:
14805:
14803:Mainland China
14800:
14795:
14789:
14787:
14783:
14782:
14780:
14779:
14774:
14769:
14764:
14759:
14754:
14749:
14744:
14739:
14734:
14729:
14724:
14719:
14714:
14709:
14704:
14699:
14694:
14689:
14684:
14679:
14674:
14668:
14666:
14657:
14649:
14648:
14645:
14644:
14642:
14641:
14636:
14631:
14626:
14620:
14618:
14612:
14611:
14609:
14608:
14603:
14598:
14593:
14588:
14583:
14578:
14573:
14568:
14563:
14557:
14555:
14551:
14550:
14548:
14547:
14542:
14537:
14532:
14526:
14521:
14516:
14511:
14506:
14501:
14496:
14491:
14486:
14481:
14476:
14471:
14466:
14460:
14458:
14454:
14453:
14451:
14450:
14445:
14440:
14434:
14429:
14424:
14419:
14413:
14408:
14403:
14397:
14395:
14391:
14390:
14388:
14387:
14382:
14376:
14374:
14370:
14369:
14367:
14366:
14361:
14356:
14350:
14348:
14344:
14343:
14341:
14340:
14334:
14332:
14323:
14319:
14318:
14315:
14314:
14312:
14311:
14305:
14303:
14297:
14296:
14294:
14293:
14288:
14283:
14278:
14273:
14267:
14265:
14259:
14258:
14256:
14255:
14249:
14244:
14239:
14237:Sinopharm CNBG
14234:
14229:
14224:
14219:
14214:
14209:
14204:
14199:
14193:
14187:
14185:
14179:
14178:
14176:
14175:
14170:
14164:
14162:
14156:
14155:
14153:
14152:
14147:
14142:
14140:Sinopharm WIBP
14137:
14135:Sinopharm BIBP
14132:
14127:
14122:
14117:
14112:
14107:
14102:
14097:
14091:
14089:
14083:
14082:
14080:
14079:
14073:
14071:
14062:
14058:
14057:
14055:
14054:
14049:
14044:
14039:
14033:
14032:
14031:
14026:
14016:
14014:EU Certificate
14011:
14006:
14001:
13996:
13994:Authorizations
13990:
13988:
13981:
13975:
13974:
13972:
13971:
13966:
13961:
13956:
13951:
13946:
13941:
13936:
13931:
13926:
13925:
13924:
13919:
13909:
13904:
13899:
13894:
13883:
13881:
13877:
13876:
13873:
13872:
13870:
13869:
13864:
13859:
13854:
13849:
13844:
13839:
13834:
13829:
13824:
13819:
13814:
13812:PeduliLindungi
13809:
13804:
13799:
13794:
13789:
13784:
13779:
13774:
13769:
13764:
13759:
13754:
13749:
13744:
13739:
13734:
13733:(South Africa)
13728:
13722:
13717:
13712:
13707:
13702:
13697:
13691:
13689:
13683:
13682:
13680:
13679:
13674:
13669:
13664:
13659:
13658:
13657:
13647:
13646:
13645:
13644:
13643:
13633:
13628:
13623:
13613:
13608:
13602:
13596:
13590:
13589:
13587:
13586:
13581:
13579:Rehabilitation
13576:
13574:Raise the line
13571:
13566:
13561:
13556:
13555:
13554:
13544:
13539:
13534:
13529:
13524:
13523:
13522:
13511:
13509:
13508:Medical topics
13501:
13500:
13490:
13489:
13486:
13485:
13482:
13481:
13479:
13478:
13473:
13471:Pregnant women
13468:
13463:
13458:
13457:
13456:
13445:
13443:
13439:
13438:
13436:
13435:
13430:
13425:
13420:
13415:
13410:
13405:
13400:
13395:
13393:Green recovery
13390:
13385:
13380:
13374:
13372:
13366:
13365:
13362:
13361:
13359:
13358:
13353:
13348:
13343:
13338:
13333:
13327:
13325:
13319:
13318:
13316:
13315:
13314:
13313:
13303:
13301:United Kingdom
13298:
13293:
13288:
13283:
13282:
13281:
13271:
13270:
13269:
13259:
13254:
13249:
13248:
13247:
13237:
13232:
13231:
13230:
13220:
13219:
13218:
13216:convoy protest
13213:
13208:
13206:labor protests
13203:
13193:
13188:
13187:
13186:
13181:
13171:
13170:
13169:
13164:
13154:
13149:
13148:
13147:
13145:convoy protest
13137:
13132:
13131:
13130:
13125:
13115:
13110:
13105:
13100:
13099:
13098:
13088:
13083:
13077:
13075:
13069:
13068:
13066:
13065:
13060:
13055:
13049:
13047:
13041:
13040:
13038:
13037:
13035:European Union
13032:
13027:
13021:
13015:
13009:
13008:
13005:
13004:
13002:
13001:
12994:
12989:
12988:
12987:
12982:
12974:
12973:
12972:
12967:
12956:
12954:
12952:Misinformation
12948:
12947:
12945:
12944:
12939:
12937:Media coverage
12934:
12928:
12922:
12918:
12917:
12914:
12913:
12911:
12910:
12905:
12900:
12894:
12892:
12886:
12885:
12883:
12882:
12877:
12872:
12867:
12862:
12857:
12851:
12849:
12845:
12844:
12842:
12841:
12836:
12831:
12826:
12821:
12816:
12815:
12814:
12804:
12803:
12802:
12797:
12792:
12782:
12777:
12776:
12775:
12764:
12762:
12758:
12757:
12755:
12754:
12749:
12744:
12739:
12734:
12729:
12728:
12727:
12717:
12712:
12706:
12704:
12700:
12699:
12697:
12696:
12691:
12689:COVID-19 scams
12686:
12680:
12674:
12668:
12667:
12664:
12663:
12661:
12660:
12655:
12649:
12647:
12641:
12640:
12638:
12637:
12632:
12627:
12622:
12617:
12615:LGBT community
12612:
12606:
12604:
12600:
12599:
12597:
12596:
12591:
12586:
12581:
12576:
12570:
12568:
12564:
12563:
12561:
12560:
12555:
12550:
12545:
12540:
12534:
12532:
12526:
12525:
12523:
12522:
12517:
12512:
12507:
12501:
12499:
12495:
12494:
12492:
12491:
12486:
12485:
12484:
12474:
12469:
12464:
12458:
12456:
12447:
12441:
12440:
12437:
12436:
12433:
12432:
12430:
12429:
12424:
12419:
12414:
12409:
12404:
12399:
12394:
12389:
12388:
12387:
12377:
12372:
12366:
12364:
12360:
12359:
12357:
12356:
12351:
12345:
12343:
12339:
12338:
12336:
12335:
12329:
12323:
12317:
12316:
12313:
12312:
12310:
12309:
12304:
12303:
12302:
12295:United Kingdom
12292:
12287:
12281:
12279:
12275:
12274:
12272:
12271:
12266:
12260:
12254:
12248:
12247:
12245:
12244:
12239:
12238:
12237:
12236:
12235:
12230:
12215:
12210:
12208:Music industry
12205:
12200:
12195:
12190:
12189:
12188:
12186:films affected
12178:
12172:
12170:
12159:
12149:
12148:
12136:
12135:
12132:
12131:
12128:
12127:
12125:
12124:
12123:
12122:
12114:
12102:
12101:
12100:
12097:Grand Princess
12093:
12081:
12075:
12073:
12069:
12068:
12066:
12065:
12060:
12055:
12050:
12049:
12048:
12043:
12033:
12028:
12023:
12018:
12013:
12008:
12007:
12006:
11996:
11995:
11994:
11989:
11979:
11978:
11977:
11967:
11962:
11961:
11960:
11955:
11944:
11942:
11934:
11933:
11930:
11929:
11927:
11926:
11921:
11916:
11915:
11914:
11909:
11899:
11894:
11893:
11892:
11887:
11882:
11877:
11871:timeline
11868:
11866:
11860:
11859:
11857:
11856:
11851:
11846:
11841:
11836:
11831:
11826:
11824:Norfolk Island
11821:
11816:
11811:
11806:
11801:
11800:
11799:
11794:
11793:
11792:
11787:
11779:
11773:timeline
11770:
11768:
11762:
11761:
11759:
11758:
11753:
11748:
11743:
11738:
11733:
11728:
11723:
11718:
11717:
11716:
11706:
11701:
11696:
11691:
11686:
11681:
11676:
11671:
11666:
11661:
11656:
11651:
11646:
11641:
11636:
11634:American Samoa
11630:
11624:
11618:
11617:
11614:
11613:
11610:
11609:
11607:
11606:
11601:
11596:
11591:
11590:
11589:
11579:
11574:
11569:
11564:
11559:
11554:
11553:
11552:
11547:
11537:
11532:
11527:
11525:South Carolina
11522:
11517:
11512:
11511:
11510:
11500:
11499:
11498:
11488:
11483:
11482:
11481:
11471:
11466:
11461:
11459:North Carolina
11456:
11455:
11454:
11453:
11452:
11437:
11432:
11427:
11422:
11421:
11420:
11410:
11405:
11400:
11395:
11390:
11385:
11380:
11379:
11378:
11377:
11376:
11366:
11356:
11355:
11354:
11344:
11339:
11334:
11329:
11324:
11319:
11314:
11309:
11304:
11299:
11294:
11289:
11284:
11279:
11274:
11269:
11268:
11267:
11262:
11252:
11247:
11246:
11245:
11235:
11233:American Samoa
11230:
11225:
11219:
11217:
11213:
11212:
11210:
11209:
11208:
11207:
11202:
11197:
11192:
11187:
11182:
11172:
11166:
11164:
11158:
11157:
11155:
11154:
11149:
11144:
11139:
11138:
11137:
11132:
11124:
11118:
11112:
11106:
11105:
11103:
11102:
11097:
11092:
11091:
11090:
11085:
11075:
11070:
11065:
11060:
11055:
11049:
11047:
11043:
11042:
11039:
11038:
11036:
11035:
11030:
11024:
11022:
11018:
11017:
11015:
11014:
11009:
11004:
10999:
10993:
10991:
10987:
10986:
10983:
10982:
10980:
10979:
10977:Sint Eustatius
10974:
10969:
10963:
10961:
10957:
10956:
10954:
10953:
10948:
10943:
10937:
10930:
10929:
10927:
10926:
10921:
10916:
10911:
10909:Cayman Islands
10906:
10901:
10895:
10893:
10887:
10886:
10884:
10883:
10882:
10881:
10871:
10866:
10861:
10856:
10851:
10846:
10841:
10836:
10831:
10830:
10829:
10819:
10814:
10809:
10803:
10801:
10794:
10790:
10789:
10787:
10786:
10781:
10780:
10779:
10769:
10768:
10767:
10766:
10765:
10750:
10745:
10744:
10743:
10738:
10733:
10728:
10723:
10718:
10713:
10712:
10711:
10706:
10701:
10688:
10683:
10678:
10673:
10668:
10663:
10658:
10653:
10652:
10651:
10641:
10636:
10631:
10630:
10629:
10619:
10618:
10617:
10607:
10601:
10599:
10595:
10594:
10592:
10591:
10586:
10581:
10575:
10573:
10566:
10558:
10557:
10554:
10553:
10551:
10550:
10545:
10540:
10535:
10529:
10527:
10523:
10522:
10520:
10519:
10514:
10513:
10512:
10502:
10497:
10491:
10489:
10488:EFTA countries
10485:
10484:
10482:
10481:
10480:
10479:
10478:
10477:
10462:
10461:
10460:
10455:
10450:
10445:
10443:Canary Islands
10440:
10435:
10425:
10420:
10415:
10414:
10413:
10403:
10398:
10393:
10392:
10391:
10381:
10376:
10371:
10366:
10361:
10360:
10359:
10354:
10344:
10343:
10342:
10337:
10332:
10327:
10326:
10325:
10320:
10315:
10302:
10297:
10292:
10291:
10290:
10285:
10275:
10274:
10273:
10268:
10263:
10258:
10253:
10248:
10243:
10233:
10232:
10231:
10221:
10216:
10215:
10214:
10204:
10202:Czech Republic
10199:
10198:
10197:
10187:
10186:
10185:
10175:
10170:
10165:
10159:
10157:
10155:European Union
10151:
10150:
10148:
10147:
10146:
10145:
10135:
10130:
10125:
10120:
10115:
10109:
10107:
10103:
10102:
10100:
10099:
10098:
10097:
10092:
10082:
10081:
10080:
10070:
10069:
10068:
10063:
10058:
10057:
10056:
10051:
10038:
10037:
10036:
10031:
10021:
10016:
10015:
10014:
10013:
10012:
10007:
10002:
9988:
9986:
9982:
9981:
9978:
9977:
9975:
9974:
9973:
9972:
9967:
9962:
9952:
9951:
9950:
9945:
9940:
9930:
9929:
9928:
9927:
9926:
9921:
9916:
9903:
9902:
9901:
9900:
9899:
9894:
9889:
9876:
9875:
9874:
9873:
9872:
9867:
9862:
9849:
9848:
9847:
9842:
9837:
9832:
9831:
9830:
9825:
9820:
9819:
9818:
9813:
9796:
9794:
9790:
9789:
9787:
9786:
9785:
9784:
9779:
9774:
9766:
9765:
9764:
9759:
9749:
9748:
9747:
9737:
9736:
9735:
9730:
9725:
9720:
9715:
9710:
9705:
9697:
9691:
9685:
9683:United Kingdom
9676:
9670:
9669:
9666:
9665:
9663:
9662:
9657:
9652:
9651:
9650:
9640:
9635:
9634:
9633:
9623:
9618:
9613:
9608:
9603:
9598:
9593:
9588:
9587:
9586:
9576:
9571:
9570:
9569:
9564:
9554:
9549:
9548:
9547:
9537:
9532:
9531:
9530:
9520:
9514:
9512:
9508:
9507:
9504:
9503:
9501:
9500:
9495:
9490:
9485:
9480:
9475:
9470:
9465:
9460:
9455:
9450:
9445:
9440:
9435:
9430:
9425:
9423:Cagayan Valley
9420:
9415:
9410:
9405:
9400:
9399:
9398:
9393:
9392:
9391:
9376:
9375:
9374:
9369:
9364:
9355:
9353:
9347:
9346:
9344:
9343:
9338:
9333:
9328:
9323:
9318:
9313:
9312:
9311:
9306:
9301:
9296:
9288:
9283:
9278:
9273:
9272:
9271:
9266:
9261:
9252:
9250:
9244:
9243:
9241:
9240:
9239:
9238:
9233:
9223:
9222:
9221:
9216:
9211:
9201:
9200:
9199:
9194:
9189:
9184:
9183:
9182:
9177:
9172:
9159:
9154:
9149:
9148:
9147:
9142:
9137:
9136:
9135:
9122:
9117:
9112:
9106:
9100:
9094:
9093:
9090:
9089:
9086:
9085:
9083:
9082:
9077:
9072:
9067:
9062:
9057:
9052:
9047:
9042:
9037:
9032:
9027:
9022:
9017:
9012:
9007:
9002:
9000:Madhya Pradesh
8997:
8992:
8987:
8986:
8985:
8975:
8970:
8965:
8960:
8955:
8950:
8945:
8940:
8939:
8938:
8928:
8923:
8918:
8913:
8908:
8903:
8898:
8896:Andhra Pradesh
8893:
8887:
8885:
8881:
8880:
8878:
8877:
8876:
8875:
8873:Vaccine Maitri
8865:
8860:
8859:
8858:
8853:
8843:
8842:
8841:
8836:
8835:
8834:
8829:
8818:
8813:
8808:
8803:
8798:
8792:
8786:
8780:
8779:
8777:
8776:
8771:
8770:
8769:
8759:
8754:
8749:
8744:
8743:
8742:
8732:
8726:
8720:
8714:
8713:
8710:
8709:
8707:
8706:
8701:
8696:
8691:
8690:
8689:
8679:
8674:
8672:Inner Mongolia
8669:
8664:
8659:
8654:
8653:
8652:
8642:
8637:
8632:
8631:
8630:
8619:
8617:
8615:Mainland China
8611:
8610:
8608:
8607:
8606:
8605:
8595:
8590:
8585:
8580:
8575:
8574:
8573:
8572:
8571:
8561:
8551:
8545:
8539:
8535:
8534:
8532:
8531:
8526:
8521:
8516:
8515:
8514:
8513:
8512:
8507:
8502:
8494:
8493:
8492:
8487:
8474:
8469:
8463:
8461:
8454:
8448:
8447:
8444:
8443:
8441:
8440:
8435:
8430:
8425:
8420:
8419:
8418:
8408:
8403:
8398:
8393:
8388:
8383:
8378:
8377:
8376:
8375:
8374:
8366:
8361:
8360:
8359:
8354:
8353:
8352:
8347:
8331:
8326:
8321:
8316:
8311:
8305:
8303:
8299:
8298:
8296:
8295:
8290:
8285:
8280:
8275:
8270:
8265:
8259:
8257:
8253:
8252:
8250:
8249:
8244:
8239:
8238:
8237:
8235:list of deaths
8227:
8222:
8217:
8212:
8207:
8202:
8197:
8191:
8189:
8185:
8184:
8182:
8181:
8176:
8171:
8166:
8161:
8160:
8159:
8149:
8144:
8139:
8134:
8129:
8124:
8119:
8114:
8109:
8104:
8099:
8094:
8088:
8086:
8082:
8081:
8079:
8078:
8077:
8076:
8069:Western Sahara
8066:
8061:
8056:
8051:
8046:
8041:
8036:
8031:
8026:
8024:Canary Islands
8021:
8015:
8013:
8006:
8005:
8004:
8002:
8001:
8000:
7993:
7976:
7975:
7963:
7962:
7959:
7958:
7955:
7954:
7952:
7951:
7946:
7940:
7938:
7937:2023 and after
7934:
7933:
7931:
7930:
7925:
7920:
7919:
7918:
7908:
7907:
7906:
7896:
7895:
7894:
7884:
7883:
7882:
7872:
7871:
7870:
7860:
7859:
7858:
7848:
7847:
7846:
7836:
7835:
7834:
7824:
7823:
7822:
7812:
7811:
7810:
7799:
7797:
7793:
7792:
7790:
7789:
7788:
7787:
7777:
7776:
7775:
7765:
7764:
7763:
7753:
7752:
7751:
7741:
7740:
7739:
7729:
7728:
7727:
7717:
7716:
7715:
7705:
7704:
7703:
7693:
7692:
7691:
7681:
7680:
7679:
7669:
7668:
7667:
7657:
7656:
7655:
7644:
7642:
7638:
7637:
7635:
7634:
7633:
7632:
7622:
7621:
7620:
7610:
7609:
7608:
7598:
7597:
7596:
7586:
7585:
7584:
7574:
7573:
7572:
7562:
7561:
7560:
7550:
7549:
7548:
7538:
7537:
7536:
7526:
7525:
7524:
7514:
7513:
7512:
7502:
7501:
7500:
7489:
7487:
7483:
7482:
7480:
7479:
7474:
7469:
7464:
7459:
7454:
7448:
7441:
7439:
7429:
7428:
7416:
7415:
7413:
7412:
7404:
7395:
7392:
7391:
7384:
7383:
7376:
7369:
7361:
7352:
7351:
7348:
7347:
7346:
7345:
7342:
7331:
7325:
7319:
7318:
7315:
7314:
7312:
7311:
7306:
7301:
7296:
7290:
7288:
7284:
7283:
7281:
7280:
7275:
7268:
7263:
7258:
7253:
7248:
7235:
7229:
7227:
7223:
7222:
7220:
7219:
7214:
7212:Katalin Karikó
7209:
7204:
7199:
7194:
7189:
7184:
7179:
7174:
7169:
7163:
7161:
7155:
7154:
7151:
7150:
7148:
7147:
7146:
7145:
7140:
7135:
7130:
7122:
7117:
7112:
7107:
7102:
7101:
7100:
7095:
7094:
7093:
7088:
7078:
7073:
7068:
7058:
7052:
7050:
7046:
7045:
7043:
7042:
7041:
7040:
7035:
7026:
7024:
7018:
7017:
7015:
7014:
7013:
7012:
7004:
7003:
7002:
6991:
6989:
6985:
6984:
6982:
6981:
6980:
6979:
6974:
6969:
6967:Herpes simplex
6964:
6959:
6954:
6949:
6941:
6940:
6939:
6934:
6929:
6921:
6916:
6915:
6914:
6909:
6901:
6896:
6891:
6886:
6885:
6884:
6879:
6874:
6869:
6867:Sinopharm BIBP
6864:
6859:
6854:
6849:
6844:
6839:
6834:
6829:
6824:
6819:
6817:Bharat Biotech
6814:
6804:
6799:
6794:
6789:
6788:
6787:
6782:
6772:
6767:
6762:
6757:
6752:
6751:
6750:
6745:
6735:
6730:
6725:
6720:
6715:
6714:
6713:
6708:
6703:
6688:
6687:
6686:
6676:
6671:
6665:
6663:
6659:
6658:
6656:
6655:
6654:
6653:
6648:
6643:
6635:
6634:
6633:
6628:
6620:
6615:
6614:
6613:
6608:
6598:
6597:
6596:
6586:
6581:
6576:
6575:
6574:
6569:
6559:
6554:
6549:
6548:
6547:
6542:
6532:
6527:
6522:
6517:
6512:
6507:
6502:
6496:
6494:
6487:
6483:
6482:
6480:
6479:
6478:
6477:
6472:
6467:
6462:
6457:
6449:
6448:
6447:
6445:Vaccine injury
6442:
6437:
6432:
6427:
6422:
6417:
6408:
6406:
6405:Administration
6402:
6401:
6399:
6398:
6393:
6388:
6379:
6362:
6361:
6360:
6355:
6347:
6342:
6336:
6334:
6330:
6329:
6327:
6326:
6321:
6316:
6311:
6306:
6305:
6304:
6294:
6288:
6286:
6282:
6281:
6249:
6248:
6241:
6234:
6226:
6220:
6219:
6204:
6193:
6180:
6168:
6160:PHG Foundation
6152:
6109:
6102:
6101:
6100:
6098:
6097:External links
6095:
6094:
6093:
6073:(10): 759–80.
6045:
5989:
5986:
5983:
5982:
5965:PipelineReview
5952:
5919:
5886:
5834:
5801:
5750:
5704:
5679:
5665:(5): 1101–23.
5643:
5616:
5580:
5553:(6520): 1022.
5537:
5504:
5486:New York Times
5471:
5441:
5409:
5375:
5349:
5300:
5257:
5242:
5216:
5167:
5152:. Bell Media.
5136:
5103:
5059:
5010:
4969:
4920:
4869:
4838:
4807:
4771:
4737:
4703:
4672:
4635:(3): 2148–57.
4615:
4581:
4532:
4494:
4440:
4413:(5): 498–507.
4396:
4355:
4311:
4281:
4240:
4197:
4137:
4128:|journal=
4102:
4076:
4012:
3981:
3930:
3878:
3837:
3778:
3729:
3677:
3655:
3602:
3552:
3521:
3491:
3460:
3429:
3392:(8): 2136–38.
3372:
3321:
3291:
3224:
3181:
3137:
3078:
3052:
3018:
2984:
2951:
2921:
2878:
2824:
2773:
2716:
2687:(10): 759–80.
2664:
2637:
2588:
2553:
2526:(7): 1719–22.
2510:
2483:(8): 1285–94.
2462:
2431:
2377:
2340:
2281:
2211:
2157:
2145:NobelPrize.org
2132:
2106:
2094:NobelPrize.org
2081:
2004:
1970:
1901:
1867:
1841:
1805:
1772:
1715:
1700:
1671:
1629:
1592:(4): 261–279.
1555:
1483:
1434:
1375:
1374:
1372:
1369:
1368:
1367:
1362:
1357:
1352:
1345:
1342:
1305:
1302:
1276:
1275:Non-amplifying
1273:
1267:
1264:
1224:
1221:
1202:
1199:
1183:Reactogenicity
1179:
1176:
1162:
1159:
1138:
1135:
1133:
1130:
1106:pseudouridines
1104:(for example,
1069:
1066:
1021:
1018:
1016:
1013:
962:
959:
891:
888:
861:
858:
840:
837:
791:
786:
755:
750:
742:) or outside (
702:
699:
625:RNA polymerase
592:
589:
464:
461:
457:mRNA-4157/V940
450:cancer vaccine
343:
340:
264:
261:
207:
206:Early research
204:
202:
199:
187:Katalin Karikó
113:Reactogenicity
15:
9:
6:
4:
3:
2:
18349:
18338:
18335:
18333:
18330:
18328:
18325:
18324:
18322:
18312:
18307:
18302:
18300:
18295:
18290:
18288:
18278:
18277:
18274:
18251:
18250:
18246:
18245:
18243:
18242:
18240:
18236:
18230:
18227:
18225:
18222:
18220:
18217:
18215:
18214:New Caledonia
18212:
18210:
18207:
18205:
18202:
18198:
18195:
18194:
18193:
18190:
18189:
18187:
18183:
18177:
18174:
18168:
18165:
18163:
18160:
18159:
18158:
18155:
18153:
18150:
18146:
18143:
18141:
18138:
18137:
18135:
18134:
18133:
18130:
18128:
18125:
18121:
18118:
18117:
18116:
18113:
18109:
18106:
18105:
18104:
18101:
18097:
18094:
18093:
18092:
18089:
18085:
18082:
18081:
18080:
18077:
18073:
18070:
18069:
18068:
18065:
18061:
18058:
18056:
18053:
18052:
18051:
18048:
18046:
18043:
18041:
18038:
18034:
18031:
18029:
18026:
18024:
18021:
18020:
18019:
18016:
18014:
18011:
18009:
18006:
18002:
17999:
17998:
17997:
17994:
17990:
17987:
17985:
17982:
17981:
17980:
17977:
17973:
17970:
17969:
17968:
17965:
17963:
17960:
17958:
17955:
17953:
17950:
17948:
17945:
17943:
17940:
17938:
17935:
17933:
17930:
17926:
17923:
17922:
17921:
17918:
17916:
17913:
17911:
17908:
17906:
17903:
17899:
17896:
17894:
17891:
17889:
17886:
17885:
17884:
17881:
17877:
17874:
17873:
17872:
17869:
17865:
17862:
17861:
17860:
17857:
17855:
17852:
17850:
17847:
17843:
17840:
17839:
17838:
17835:
17831:
17828:
17827:
17826:
17823:
17821:
17818:
17814:
17811:
17810:
17809:
17806:
17802:
17801:Faroe Islands
17799:
17797:
17794:
17793:
17792:
17789:
17787:
17784:
17782:
17779:
17777:
17774:
17770:
17767:
17766:
17765:
17762:
17760:
17757:
17753:
17750:
17749:
17748:
17745:
17743:
17740:
17736:
17733:
17732:
17731:
17728:
17726:
17723:
17722:
17720:
17718:
17714:
17708:
17705:
17701:
17698:
17697:
17696:
17693:
17689:
17686:
17685:
17684:
17681:
17677:
17674:
17673:
17672:
17669:
17665:
17662:
17661:
17660:
17657:
17653:
17650:
17649:
17648:
17645:
17643:
17640:
17636:
17633:
17632:
17631:
17628:
17626:
17623:
17621:
17618:
17614:
17611:
17609:
17606:
17605:
17604:
17601:
17599:
17596:
17594:
17591:
17587:
17584:
17582:
17579:
17577:
17574:
17573:
17572:
17569:
17567:
17564:
17560:
17557:
17555:
17552:
17550:
17547:
17546:
17545:
17542:
17538:
17535:
17534:
17533:
17530:
17526:
17523:
17522:
17521:
17518:
17514:
17511:
17510:
17509:
17506:
17502:
17499:
17497:
17494:
17493:
17492:
17489:
17485:
17482:
17480:
17477:
17476:
17475:
17472:
17470:
17467:
17465:
17462:
17460:
17457:
17453:
17450:
17449:
17448:
17445:
17443:
17440:
17438:
17435:
17431:
17428:
17427:
17426:
17423:
17419:
17416:
17415:
17414:
17411:
17409:
17406:
17402:
17399:
17398:
17397:
17394:
17390:
17387:
17386:
17385:
17382:
17380:
17377:
17375:
17372:
17370:
17367:
17365:
17362:
17360:
17357:
17353:
17350:
17348:
17345:
17343:
17340:
17338:
17335:
17333:
17330:
17328:
17325:
17324:
17323:
17320:
17316:
17313:
17311:
17308:
17307:
17306:
17303:
17301:
17298:
17294:
17291:
17290:
17289:
17286:
17282:
17279:
17278:
17277:
17274:
17272:
17269:
17267:
17264:
17260:
17257:
17256:
17255:
17252:
17250:
17247:
17246:
17244:
17240:
17234:
17231:
17229:
17226:
17222:
17219:
17218:
17217:
17216:United States
17214:
17212:
17209:
17207:
17204:
17202:
17199:
17197:
17194:
17190:
17187:
17186:
17185:
17182:
17180:
17177:
17175:
17172:
17170:
17167:
17165:
17162:
17160:
17157:
17155:
17152:
17150:
17147:
17143:
17140:
17139:
17138:
17135:
17133:
17130:
17126:
17123:
17122:
17121:
17118:
17114:
17111:
17109:
17106:
17105:
17104:
17101:
17099:
17096:
17094:
17091:
17089:
17086:
17085:
17083:
17079:
17071:
17068:
17067:
17066:
17063:
17061:
17058:
17056:
17053:
17051:
17048:
17046:
17043:
17041:
17038:
17036:
17033:
17031:
17028:
17024:
17021:
17020:
17019:
17016:
17014:
17011:
17009:
17006:
17004:
17001:
16999:
16996:
16992:
16989:
16988:
16987:
16984:
16982:
16979:
16977:
16974:
16972:
16969:
16967:
16964:
16962:
16959:
16957:
16954:
16952:
16949:
16947:
16944:
16942:
16939:
16937:
16934:
16930:
16927:
16926:
16925:
16922:
16920:
16917:
16915:
16912:
16910:
16907:
16905:
16902:
16900:
16897:
16895:
16892:
16890:
16887:
16885:
16882:
16880:
16877:
16875:
16872:
16870:
16867:
16866:
16864:
16860:
16853:
16850:
16848:
16845:
16841:
16838:
16837:
16836:
16833:
16829:
16826:
16822:
16819:
16817:
16814:
16812:
16809:
16807:
16804:
16802:
16799:
16797:
16794:
16792:
16791:February 2021
16789:
16787:
16784:
16782:
16781:December 2020
16779:
16777:
16776:November 2020
16774:
16772:
16769:
16767:
16764:
16762:
16759:
16757:
16754:
16752:
16749:
16747:
16744:
16742:
16739:
16737:
16734:
16732:
16731:February 2020
16729:
16727:
16724:
16723:
16722:
16719:
16718:
16716:
16714:
16711:
16709:
16706:
16704:
16701:
16700:
16698:
16694:
16690:
16683:
16679:
16665:
16662:
16661:
16659:
16655:
16649:
16646:
16644:
16643:Qiu Menghuang
16641:
16639:
16636:
16634:
16631:
16629:
16626:
16624:
16621:
16619:
16616:
16614:
16613:Brett Crozier
16611:
16609:
16606:
16605:
16603:
16599:
16588:
16585:
16582:
16581:Lawrence Wong
16579:
16576:
16573:
16570:
16567:
16564:
16561:
16558:
16555:
16552:
16551:Harsh Vardhan
16549:
16546:
16543:
16540:
16537:
16534:
16531:
16528:
16525:
16522:
16519:
16516:
16513:
16510:
16507:
16504:
16501:
16498:
16495:
16492:
16489:
16486:
16483:
16480:
16477:
16474:
16471:
16468:
16467:Ala Nemerenco
16465:
16462:
16459:
16456:
16453:
16450:
16447:
16444:
16441:
16438:
16435:
16432:
16429:
16426:
16423:
16420:
16417:
16414:
16411:
16409:(South Korea)
16408:
16405:
16402:
16399:
16396:
16393:
16390:
16387:
16384:
16381:
16378:
16375:
16372:
16371:Graça Freitas
16369:
16366:
16363:
16360:
16359:Anthony Fauci
16357:
16355:(Philippines)
16354:
16351:
16348:
16345:
16342:
16339:
16337:(Puerto Rico)
16336:
16335:Carmen Deseda
16333:
16330:
16327:
16324:
16321:
16318:
16315:
16312:
16309:
16306:
16303:
16300:
16297:
16294:
16291:
16289:(New Zealand)
16288:
16285:
16282:
16279:
16278:
16276:
16272:
16265:
16262:
16259:
16256:
16253:
16252:Bruce Aylward
16250:
16247:
16244:
16243:
16241:
16237:
16234:
16230:
16224:
16223:Zhong Nanshan
16221:
16219:
16216:
16214:
16211:
16209:
16206:
16204:
16201:
16199:
16198:Drew Weissman
16196:
16194:
16191:
16189:
16186:
16184:
16181:
16179:
16176:
16174:
16173:Moncef Slaoui
16171:
16169:
16166:
16164:
16163:Camilla Rothe
16161:
16159:
16156:
16154:
16151:
16149:
16146:
16144:
16143:W. Ian Lipkin
16141:
16139:
16136:
16134:
16131:
16129:
16126:
16124:
16121:
16119:
16118:Kentaro Iwata
16116:
16114:
16111:
16109:
16108:Sarah Gilbert
16106:
16104:
16101:
16099:
16098:George F. Gao
16096:
16094:
16091:
16089:
16088:Neil Ferguson
16086:
16084:
16081:
16079:
16076:
16074:
16071:
16069:
16066:
16064:
16061:
16059:
16056:
16054:
16051:
16050:
16048:
16046:
16042:
16036:
16035:Zhang Wenhong
16033:
16031:
16028:
16026:
16023:
16021:
16018:
16016:
16013:
16011:
16008:
16007:
16005:
16003:professionals
15999:
15995:
15988:
15984:
15961:
15960:Artist Relief
15958:
15955:
15952:
15949:
15948:PM CARES Fund
15946:
15945:
15943:
15939:
15932:
15929:
15926:
15923:
15920:
15917:
15914:
15911:
15908:
15905:
15902:
15899:
15896:
15893:
15890:
15887:
15884:
15881:
15878:
15875:
15872:
15869:
15867:(Philippines)
15866:
15863:
15861:(Philippines)
15860:
15857:
15854:
15851:
15848:
15845:
15842:
15839:
15836:
15833:
15830:
15827:
15824:
15821:
15818:
15815:
15812:
15809:
15806:
15803:
15802:
15800:
15794:
15787:
15784:
15781:
15778:
15776:(South Korea)
15775:
15772:
15770:
15767:
15764:
15761:
15758:
15755:
15754:
15752:
15746:
15739:
15736:
15733:
15730:
15727:
15724:
15721:
15718:
15717:
15714:
15711:
15707:
15702:
15700:
15696:
15693:
15691:Organizations
15689:
15676:
15673:
15670:
15667:
15663:
15660:
15658:
15655:
15653:
15650:
15648:
15645:
15643:
15640:
15639:
15637:
15634:
15633:
15632:
15629:
15626:
15623:
15620:
15617:
15614:
15611:
15609:(Philippines)
15608:
15605:
15602:
15599:
15597:(North Korea)
15596:
15593:
15590:
15587:
15584:
15581:
15579:
15576:
15573:
15570:
15568:
15565:
15564:
15562:
15558:
15552:
15549:
15547:
15544:
15542:
15539:
15537:
15534:
15532:
15529:
15527:
15524:
15522:
15519:
15518:
15516:
15512:
15509:
15505:Hospitals and
15503:
15499:
15492:
15488:
15474:
15471:
15469:
15466:
15464:
15461:
15459:
15456:
15455:
15453:
15449:
15441:
15438:
15437:
15436:
15433:
15431:
15428:
15426:
15423:
15421:
15418:
15416:
15413:
15411:
15408:
15406:
15403:
15401:
15398:
15396:
15393:
15391:
15388:
15386:
15383:
15381:
15378:
15376:
15373:
15372:
15370:
15366:
15362:
15358:
15353:
15349:
15329:
15326:
15324:
15321:
15320:
15318:
15314:
15311:
15309:
15306:
15304:
15301:
15300:
15299:
15296:
15295:
15293:
15291:
15287:
15281:
15278:
15276:
15273:
15271:
15268:
15266:
15263:
15261:
15258:
15256:
15253:
15251:
15248:
15243:
15241:
15238:
15237:
15236:
15233:
15232:
15230:
15228:
15224:
15217:
15214:
15211:
15208:
15205:
15202:
15200:
15197:
15195:
15192:
15188:
15187:Dexamethasone
15185:
15183:
15180:
15179:
15178:
15175:
15173:
15170:
15169:
15166:
15163:
15161:
15157:
15143:
15140:
15139:
15137:
15133:
15127:
15124:
15122:
15119:
15117:
15114:
15112:
15109:
15108:
15106:
15104:South America
15102:
15096:
15093:
15091:
15088:
15086:
15083:
15082:
15080:
15076:
15068:
15065:
15064:
15063:
15062:United States
15060:
15058:
15055:
15053:
15050:
15048:
15045:
15041:
15038:
15036:
15033:
15032:
15031:
15028:
15027:
15025:
15023:North America
15021:
15015:
15012:
15010:
15007:
15005:
15002:
15000:
14997:
14995:
14992:
14990:
14987:
14985:
14982:
14980:
14977:
14975:
14972:
14970:
14967:
14965:
14962:
14960:
14957:
14955:
14952:
14950:
14947:
14945:
14942:
14940:
14937:
14935:
14932:
14930:
14927:
14925:
14922:
14920:
14917:
14915:
14912:
14910:
14907:
14906:
14904:
14900:
14894:
14891:
14889:
14886:
14884:
14881:
14879:
14876:
14874:
14871:
14869:
14866:
14864:
14861:
14859:
14856:
14854:
14851:
14849:
14846:
14844:
14841:
14839:
14836:
14834:
14831:
14829:
14826:
14824:
14821:
14819:
14816:
14814:
14811:
14809:
14806:
14804:
14801:
14799:
14796:
14794:
14791:
14790:
14788:
14784:
14778:
14775:
14773:
14770:
14768:
14765:
14763:
14760:
14758:
14755:
14753:
14750:
14748:
14745:
14743:
14740:
14738:
14735:
14733:
14730:
14728:
14725:
14723:
14720:
14718:
14715:
14713:
14710:
14708:
14705:
14703:
14700:
14698:
14695:
14693:
14690:
14688:
14685:
14683:
14680:
14678:
14675:
14673:
14670:
14669:
14667:
14665:
14661:
14658:
14656:
14650:
14640:
14637:
14635:
14632:
14630:
14627:
14625:
14622:
14621:
14619:
14617:
14613:
14607:
14604:
14602:
14599:
14597:
14594:
14592:
14589:
14587:
14584:
14582:
14579:
14577:
14574:
14572:
14569:
14567:
14564:
14562:
14559:
14558:
14556:
14552:
14546:
14543:
14541:
14538:
14536:
14533:
14530:
14527:
14525:
14522:
14520:
14517:
14515:
14512:
14510:
14507:
14505:
14502:
14500:
14497:
14495:
14492:
14490:
14487:
14485:
14482:
14480:
14477:
14475:
14472:
14470:
14467:
14465:
14462:
14461:
14459:
14455:
14449:
14446:
14444:
14441:
14438:
14435:
14433:
14432:PTX-COVID19-B
14430:
14428:
14425:
14423:
14420:
14417:
14414:
14412:
14409:
14407:
14404:
14402:
14399:
14398:
14396:
14392:
14386:
14383:
14381:
14378:
14377:
14375:
14371:
14365:
14362:
14360:
14357:
14355:
14352:
14351:
14349:
14345:
14339:
14336:
14335:
14333:
14331:
14327:
14324:
14320:
14310:
14307:
14306:
14304:
14302:
14298:
14292:
14291:Sputnik Light
14289:
14287:
14284:
14282:
14279:
14277:
14274:
14272:
14269:
14268:
14266:
14264:
14260:
14253:
14250:
14248:
14247:Soberana Plus
14245:
14243:
14240:
14238:
14235:
14233:
14232:Razi Cov Pars
14230:
14228:
14225:
14223:
14220:
14218:
14215:
14213:
14210:
14208:
14205:
14203:
14200:
14197:
14194:
14192:
14189:
14188:
14186:
14184:
14180:
14174:
14171:
14169:
14166:
14165:
14163:
14161:
14157:
14151:
14148:
14146:
14143:
14141:
14138:
14136:
14133:
14131:
14128:
14126:
14123:
14121:
14118:
14116:
14113:
14111:
14108:
14106:
14103:
14101:
14098:
14096:
14093:
14092:
14090:
14088:
14084:
14078:
14075:
14074:
14072:
14070:
14066:
14063:
14059:
14053:
14050:
14048:
14045:
14043:
14040:
14037:
14034:
14030:
14027:
14025:
14022:
14021:
14020:
14017:
14015:
14012:
14010:
14007:
14005:
14002:
14000:
13997:
13995:
13992:
13991:
13989:
13985:
13982:
13980:
13976:
13970:
13967:
13965:
13962:
13960:
13957:
13955:
13952:
13950:
13947:
13945:
13942:
13940:
13937:
13935:
13932:
13930:
13927:
13923:
13922:United States
13920:
13918:
13915:
13914:
13913:
13910:
13908:
13905:
13903:
13902:COVID fatigue
13900:
13898:
13895:
13892:
13888:
13885:
13884:
13882:
13878:
13868:
13865:
13863:
13860:
13858:
13857:TraceTogether
13855:
13853:
13852:TousAntiCovid
13850:
13848:
13845:
13843:
13840:
13838:
13835:
13833:
13830:
13828:
13825:
13823:
13820:
13818:
13815:
13813:
13810:
13808:
13805:
13803:
13800:
13798:
13795:
13793:
13790:
13788:
13785:
13783:
13782:LeaveHomeSafe
13780:
13778:
13775:
13773:
13770:
13768:
13765:
13763:
13760:
13758:
13755:
13753:
13750:
13748:
13745:
13743:
13740:
13738:
13735:
13732:
13731:COVID AlertSA
13729:
13726:
13723:
13721:
13718:
13716:
13713:
13711:
13708:
13706:
13703:
13701:
13698:
13696:
13693:
13692:
13690:
13688:
13684:
13678:
13675:
13673:
13670:
13668:
13665:
13663:
13660:
13656:
13653:
13652:
13651:
13648:
13642:
13639:
13638:
13637:
13634:
13632:
13629:
13627:
13624:
13622:
13619:
13618:
13617:
13614:
13612:
13609:
13607:
13604:
13603:
13600:
13597:
13591:
13585:
13582:
13580:
13577:
13575:
13572:
13570:
13567:
13565:
13562:
13560:
13557:
13553:
13550:
13549:
13548:
13547:Mental health
13545:
13543:
13540:
13538:
13535:
13533:
13530:
13528:
13525:
13521:
13518:
13517:
13516:
13513:
13512:
13510:
13506:
13502:
13498:Health issues
13495:
13491:
13477:
13474:
13472:
13469:
13467:
13464:
13462:
13459:
13455:
13452:
13451:
13450:
13447:
13446:
13444:
13440:
13434:
13431:
13429:
13426:
13424:
13421:
13419:
13416:
13414:
13413:Superspreader
13411:
13409:
13406:
13404:
13401:
13399:
13396:
13394:
13391:
13389:
13386:
13384:
13383:Doomscrolling
13381:
13379:
13376:
13375:
13373:
13371:
13367:
13357:
13354:
13352:
13349:
13347:
13344:
13342:
13339:
13337:
13334:
13332:
13329:
13328:
13326:
13324:
13320:
13312:
13309:
13308:
13307:
13306:United States
13304:
13302:
13299:
13297:
13294:
13292:
13289:
13287:
13284:
13280:
13277:
13276:
13275:
13272:
13268:
13265:
13264:
13263:
13260:
13258:
13255:
13253:
13250:
13246:
13243:
13242:
13241:
13238:
13236:
13233:
13229:
13226:
13225:
13224:
13221:
13217:
13214:
13212:
13209:
13207:
13204:
13202:
13199:
13198:
13197:
13194:
13192:
13189:
13185:
13184:2022 protests
13182:
13180:
13179:2021 protests
13177:
13176:
13175:
13172:
13168:
13165:
13163:
13160:
13159:
13158:
13155:
13153:
13150:
13146:
13143:
13142:
13141:
13138:
13136:
13133:
13129:
13128:2021 protests
13126:
13124:
13123:2020 protests
13121:
13120:
13119:
13116:
13114:
13111:
13109:
13106:
13104:
13101:
13097:
13094:
13093:
13092:
13089:
13087:
13084:
13082:
13079:
13078:
13076:
13074:
13070:
13064:
13061:
13059:
13056:
13054:
13051:
13050:
13048:
13046:
13042:
13036:
13033:
13031:
13028:
13026:
13023:
13022:
13019:
13016:
13014:
13010:
13000:
12999:
12995:
12993:
12990:
12986:
12983:
12981:
12978:
12977:
12975:
12971:
12970:United States
12968:
12966:
12963:
12962:
12961:
12958:
12957:
12955:
12953:
12949:
12943:
12940:
12938:
12935:
12933:
12930:
12929:
12926:
12923:
12919:
12909:
12906:
12904:
12901:
12899:
12896:
12895:
12893:
12891:
12887:
12881:
12880:Food security
12878:
12876:
12875:Oil price war
12873:
12871:
12868:
12866:
12863:
12861:
12858:
12856:
12853:
12852:
12850:
12846:
12840:
12837:
12835:
12832:
12830:
12827:
12825:
12822:
12820:
12817:
12813:
12810:
12809:
12808:
12805:
12801:
12798:
12796:
12793:
12791:
12788:
12787:
12786:
12785:Food industry
12783:
12781:
12778:
12774:
12771:
12770:
12769:
12766:
12765:
12763:
12759:
12753:
12750:
12748:
12745:
12743:
12740:
12738:
12735:
12733:
12730:
12726:
12723:
12722:
12721:
12718:
12716:
12713:
12711:
12708:
12707:
12705:
12701:
12695:
12692:
12690:
12687:
12685:
12682:
12681:
12678:
12675:
12673:
12669:
12659:
12656:
12654:
12651:
12650:
12648:
12646:
12642:
12636:
12633:
12631:
12628:
12626:
12623:
12621:
12618:
12616:
12613:
12611:
12608:
12607:
12605:
12601:
12595:
12592:
12590:
12587:
12585:
12582:
12580:
12577:
12575:
12572:
12571:
12569:
12565:
12559:
12556:
12554:
12551:
12549:
12546:
12544:
12541:
12539:
12536:
12535:
12533:
12531:
12527:
12521:
12518:
12516:
12513:
12511:
12508:
12506:
12503:
12502:
12500:
12496:
12490:
12487:
12483:
12480:
12479:
12478:
12475:
12473:
12470:
12468:
12465:
12463:
12460:
12459:
12457:
12455:
12454:Social impact
12451:
12448:
12442:
12428:
12425:
12423:
12420:
12418:
12415:
12413:
12410:
12408:
12405:
12403:
12400:
12398:
12395:
12393:
12392:Combat sports
12390:
12386:
12383:
12382:
12381:
12378:
12376:
12373:
12371:
12368:
12367:
12365:
12361:
12355:
12352:
12350:
12347:
12346:
12344:
12340:
12334:
12331:
12330:
12327:
12324:
12322:
12318:
12308:
12307:United States
12305:
12301:
12298:
12297:
12296:
12293:
12291:
12288:
12286:
12283:
12282:
12280:
12276:
12270:
12269:Homeschooling
12267:
12265:
12262:
12261:
12258:
12255:
12253:
12249:
12243:
12240:
12234:
12231:
12229:
12226:
12225:
12224:
12221:
12220:
12219:
12216:
12214:
12211:
12209:
12206:
12204:
12201:
12199:
12196:
12194:
12191:
12187:
12184:
12183:
12182:
12179:
12177:
12174:
12173:
12171:
12169:
12163:
12160:
12158:entertainment
12154:
12150:
12146:
12141:
12137:
12121:
12120:
12115:
12113:
12112:
12108:
12107:
12106:
12103:
12099:
12098:
12094:
12092:
12091:
12087:
12086:
12085:
12082:
12080:
12077:
12076:
12074:
12070:
12064:
12061:
12059:
12056:
12054:
12051:
12047:
12044:
12042:
12039:
12038:
12037:
12034:
12032:
12029:
12027:
12024:
12022:
12021:French Guiana
12019:
12017:
12014:
12012:
12009:
12005:
12002:
12001:
12000:
11997:
11993:
11992:Easter Island
11990:
11988:
11985:
11984:
11983:
11980:
11976:
11973:
11972:
11971:
11968:
11966:
11963:
11959:
11956:
11954:
11951:
11950:
11949:
11946:
11945:
11943:
11941:
11935:
11925:
11922:
11920:
11919:social impact
11917:
11913:
11910:
11908:
11905:
11904:
11903:
11900:
11898:
11895:
11891:
11888:
11886:
11883:
11881:
11878:
11876:
11873:
11872:
11870:
11869:
11867:
11865:
11861:
11855:
11852:
11850:
11847:
11845:
11842:
11840:
11837:
11835:
11832:
11830:
11827:
11825:
11822:
11820:
11817:
11815:
11812:
11810:
11807:
11805:
11802:
11798:
11795:
11791:
11790:July–December
11788:
11786:
11783:
11782:
11780:
11778:
11775:
11774:
11772:
11771:
11769:
11767:
11763:
11757:
11754:
11752:
11749:
11747:
11744:
11742:
11739:
11737:
11734:
11732:
11729:
11727:
11724:
11722:
11719:
11715:
11712:
11711:
11710:
11707:
11705:
11702:
11700:
11697:
11695:
11692:
11690:
11689:New Caledonia
11687:
11685:
11682:
11680:
11677:
11675:
11672:
11670:
11667:
11665:
11662:
11660:
11657:
11655:
11652:
11650:
11647:
11645:
11644:Easter Island
11642:
11640:
11637:
11635:
11632:
11631:
11628:
11625:
11623:
11619:
11605:
11602:
11600:
11597:
11595:
11594:West Virginia
11592:
11588:
11585:
11584:
11583:
11580:
11578:
11575:
11573:
11570:
11568:
11565:
11563:
11560:
11558:
11555:
11551:
11548:
11546:
11543:
11542:
11541:
11538:
11536:
11533:
11531:
11528:
11526:
11523:
11521:
11518:
11516:
11513:
11509:
11506:
11505:
11504:
11501:
11497:
11494:
11493:
11492:
11489:
11487:
11484:
11480:
11477:
11476:
11475:
11472:
11470:
11467:
11465:
11462:
11460:
11457:
11451:
11448:
11447:
11446:
11445:New York City
11443:
11442:
11441:
11438:
11436:
11433:
11431:
11428:
11426:
11425:New Hampshire
11423:
11419:
11416:
11415:
11414:
11411:
11409:
11406:
11404:
11401:
11399:
11396:
11394:
11391:
11389:
11386:
11384:
11381:
11375:
11372:
11371:
11370:
11367:
11365:
11362:
11361:
11360:
11359:Massachusetts
11357:
11353:
11350:
11349:
11348:
11345:
11343:
11340:
11338:
11335:
11333:
11330:
11328:
11325:
11323:
11320:
11318:
11315:
11313:
11310:
11308:
11305:
11303:
11300:
11298:
11295:
11293:
11290:
11288:
11285:
11283:
11280:
11278:
11275:
11273:
11270:
11266:
11265:S.F. Bay Area
11263:
11261:
11258:
11257:
11256:
11253:
11251:
11248:
11244:
11243:Navajo Nation
11241:
11240:
11239:
11236:
11234:
11231:
11229:
11226:
11224:
11221:
11220:
11218:
11214:
11206:
11203:
11201:
11198:
11196:
11193:
11191:
11188:
11186:
11183:
11181:
11178:
11177:
11176:
11173:
11171:
11168:
11167:
11165:
11163:
11159:
11153:
11150:
11148:
11145:
11143:
11142:social impact
11140:
11136:
11133:
11131:
11128:
11127:
11125:
11123:
11120:
11119:
11116:
11113:
11111:
11110:United States
11107:
11101:
11098:
11096:
11093:
11089:
11086:
11084:
11081:
11080:
11079:
11076:
11074:
11071:
11069:
11066:
11064:
11061:
11059:
11056:
11054:
11051:
11050:
11048:
11044:
11034:
11031:
11029:
11026:
11025:
11023:
11019:
11013:
11010:
11008:
11005:
11003:
11000:
10998:
10995:
10994:
10992:
10988:
10978:
10975:
10973:
10970:
10968:
10965:
10964:
10962:
10958:
10952:
10949:
10947:
10944:
10942:
10939:
10938:
10935:
10931:
10925:
10922:
10920:
10917:
10915:
10912:
10910:
10907:
10905:
10902:
10900:
10897:
10896:
10894:
10892:
10888:
10880:
10877:
10876:
10875:
10872:
10870:
10867:
10865:
10862:
10860:
10857:
10855:
10852:
10850:
10847:
10845:
10842:
10840:
10837:
10835:
10832:
10828:
10825:
10824:
10823:
10820:
10818:
10815:
10813:
10810:
10808:
10805:
10804:
10802:
10798:
10795:
10791:
10785:
10782:
10778:
10775:
10774:
10773:
10770:
10764:
10761:
10760:
10759:
10756:
10755:
10754:
10751:
10749:
10746:
10742:
10739:
10737:
10734:
10732:
10729:
10727:
10724:
10722:
10719:
10717:
10714:
10710:
10707:
10705:
10702:
10700:
10697:
10696:
10694:
10693:
10692:
10689:
10687:
10684:
10682:
10679:
10677:
10674:
10672:
10669:
10667:
10666:New Brunswick
10664:
10662:
10659:
10657:
10654:
10650:
10647:
10646:
10645:
10642:
10640:
10637:
10635:
10632:
10628:
10625:
10624:
10623:
10620:
10616:
10613:
10612:
10611:
10608:
10606:
10603:
10602:
10600:
10596:
10590:
10587:
10585:
10582:
10580:
10577:
10576:
10574:
10570:
10567:
10565:
10559:
10549:
10546:
10544:
10541:
10539:
10536:
10534:
10531:
10530:
10528:
10524:
10518:
10515:
10511:
10508:
10507:
10506:
10503:
10501:
10500:Liechtenstein
10498:
10496:
10493:
10492:
10490:
10486:
10476:
10473:
10472:
10471:
10468:
10467:
10466:
10463:
10459:
10456:
10454:
10451:
10449:
10446:
10444:
10441:
10439:
10436:
10434:
10431:
10430:
10429:
10426:
10424:
10421:
10419:
10416:
10412:
10409:
10408:
10407:
10404:
10402:
10399:
10397:
10394:
10390:
10387:
10386:
10385:
10382:
10380:
10377:
10375:
10372:
10370:
10367:
10365:
10362:
10358:
10355:
10353:
10350:
10349:
10348:
10345:
10341:
10338:
10336:
10335:social impact
10333:
10331:
10328:
10324:
10321:
10319:
10316:
10314:
10311:
10310:
10308:
10307:
10306:
10303:
10301:
10298:
10296:
10293:
10289:
10286:
10284:
10281:
10280:
10279:
10276:
10272:
10269:
10267:
10264:
10262:
10259:
10257:
10254:
10252:
10249:
10247:
10246:French Guiana
10244:
10242:
10239:
10238:
10237:
10234:
10230:
10227:
10226:
10225:
10222:
10220:
10217:
10213:
10212:Faroe Islands
10210:
10209:
10208:
10205:
10203:
10200:
10196:
10193:
10192:
10191:
10188:
10184:
10181:
10180:
10179:
10176:
10174:
10171:
10169:
10166:
10164:
10161:
10160:
10158:
10156:
10152:
10144:
10141:
10140:
10139:
10136:
10134:
10131:
10129:
10126:
10124:
10121:
10119:
10116:
10114:
10111:
10110:
10108:
10104:
10096:
10093:
10091:
10088:
10087:
10086:
10083:
10079:
10076:
10075:
10074:
10071:
10067:
10064:
10062:
10059:
10055:
10052:
10050:
10047:
10046:
10044:
10043:
10042:
10039:
10035:
10032:
10030:
10027:
10026:
10025:
10022:
10020:
10017:
10011:
10008:
10006:
10003:
10001:
9998:
9997:
9995:
9994:
9993:
9990:
9989:
9987:
9983:
9971:
9968:
9966:
9963:
9961:
9958:
9957:
9956:
9953:
9949:
9946:
9944:
9941:
9939:
9936:
9935:
9934:
9931:
9925:
9922:
9920:
9917:
9915:
9912:
9911:
9909:
9908:
9907:
9904:
9898:
9895:
9893:
9890:
9888:
9885:
9884:
9882:
9881:
9880:
9877:
9871:
9868:
9866:
9863:
9861:
9858:
9857:
9855:
9854:
9853:
9850:
9846:
9843:
9841:
9838:
9836:
9833:
9829:
9826:
9824:
9821:
9817:
9816:July–December
9814:
9812:
9809:
9808:
9807:2020
9806:
9805:
9803:
9802:
9801:
9798:
9797:
9795:
9791:
9783:
9780:
9778:
9775:
9773:
9770:
9769:
9768:impact
9767:
9763:
9760:
9758:
9755:
9754:
9753:
9750:
9746:
9743:
9742:
9741:
9738:
9734:
9731:
9729:
9726:
9724:
9721:
9719:
9716:
9714:
9711:
9709:
9706:
9704:
9701:
9700:
9698:
9696:
9693:
9692:
9689:
9686:
9684:
9680:
9677:
9675:
9671:
9661:
9658:
9656:
9653:
9649:
9646:
9645:
9644:
9641:
9639:
9636:
9632:
9629:
9628:
9627:
9624:
9622:
9619:
9617:
9614:
9612:
9609:
9607:
9604:
9602:
9599:
9597:
9594:
9592:
9589:
9585:
9582:
9581:
9580:
9577:
9575:
9572:
9568:
9567:South Ossetia
9565:
9563:
9560:
9559:
9558:
9555:
9553:
9550:
9546:
9543:
9542:
9541:
9538:
9536:
9533:
9529:
9526:
9525:
9524:
9521:
9519:
9516:
9515:
9513:
9509:
9499:
9496:
9494:
9491:
9489:
9486:
9484:
9481:
9479:
9476:
9474:
9471:
9469:
9466:
9464:
9463:Ilocos Region
9461:
9459:
9456:
9454:
9451:
9449:
9446:
9444:
9441:
9439:
9438:Central Luzon
9436:
9434:
9431:
9429:
9426:
9424:
9421:
9419:
9416:
9414:
9411:
9409:
9406:
9404:
9401:
9397:
9394:
9390:
9387:
9386:
9385:
9382:
9381:
9380:
9377:
9373:
9370:
9368:
9365:
9363:
9360:
9359:
9357:
9356:
9354:
9352:
9348:
9342:
9339:
9337:
9334:
9332:
9329:
9327:
9324:
9322:
9319:
9317:
9314:
9310:
9307:
9305:
9302:
9300:
9297:
9295:
9292:
9291:
9289:
9287:
9284:
9282:
9279:
9277:
9274:
9270:
9267:
9265:
9262:
9260:
9257:
9256:
9255:impact
9254:
9253:
9251:
9249:
9245:
9237:
9234:
9232:
9229:
9228:
9227:
9224:
9220:
9217:
9215:
9212:
9210:
9207:
9206:
9205:
9202:
9198:
9195:
9193:
9190:
9188:
9185:
9181:
9178:
9176:
9173:
9171:
9168:
9167:
9165:
9164:
9163:
9160:
9158:
9155:
9153:
9150:
9146:
9143:
9141:
9138:
9134:
9131:
9130:
9128:
9127:
9126:
9123:
9121:
9118:
9116:
9113:
9111:
9108:
9107:
9104:
9101:
9099:
9095:
9081:
9078:
9076:
9073:
9071:
9070:Uttar Pradesh
9068:
9066:
9063:
9061:
9058:
9056:
9053:
9051:
9048:
9046:
9043:
9041:
9038:
9036:
9033:
9031:
9028:
9026:
9023:
9021:
9018:
9016:
9013:
9011:
9008:
9006:
9003:
9001:
8998:
8996:
8993:
8991:
8988:
8984:
8981:
8980:
8979:
8976:
8974:
8971:
8969:
8966:
8964:
8961:
8959:
8956:
8954:
8951:
8949:
8946:
8944:
8941:
8937:
8934:
8933:
8932:
8929:
8927:
8924:
8922:
8919:
8917:
8914:
8912:
8909:
8907:
8904:
8902:
8899:
8897:
8894:
8892:
8889:
8888:
8886:
8882:
8874:
8871:
8870:
8869:
8866:
8864:
8861:
8857:
8854:
8852:
8851:PM CARES Fund
8849:
8848:
8847:
8844:
8840:
8837:
8833:
8832:June–December
8830:
8828:
8825:
8824:
8823:2020
8822:
8821:
8819:
8817:
8814:
8812:
8809:
8807:
8804:
8802:
8799:
8797:
8794:
8793:
8790:
8787:
8785:
8781:
8775:
8772:
8768:
8765:
8764:
8763:
8760:
8758:
8755:
8753:
8750:
8748:
8745:
8741:
8738:
8737:
8736:
8733:
8731:
8728:
8727:
8724:
8721:
8719:
8715:
8705:
8702:
8700:
8697:
8695:
8692:
8688:
8687:2022 outbreak
8685:
8684:
8683:
8680:
8678:
8675:
8673:
8670:
8668:
8665:
8663:
8660:
8658:
8655:
8651:
8648:
8647:
8646:
8643:
8641:
8638:
8636:
8633:
8629:
8626:
8625:
8624:
8621:
8620:
8618:
8616:
8612:
8604:
8601:
8600:
8599:
8596:
8594:
8591:
8589:
8586:
8584:
8581:
8579:
8576:
8570:
8567:
8566:
8565:
8562:
8560:
8557:
8556:
8555:
8552:
8550:
8547:
8546:
8543:
8540:
8536:
8530:
8527:
8525:
8522:
8520:
8517:
8511:
8508:
8506:
8503:
8501:
8498:
8497:
8496:impact
8495:
8491:
8490:July–December
8488:
8486:
8483:
8482:
8480:
8479:
8478:
8475:
8473:
8470:
8468:
8465:
8464:
8462:
8460:Central/North
8458:
8455:
8453:
8449:
8439:
8436:
8434:
8431:
8429:
8426:
8424:
8421:
8417:
8414:
8413:
8412:
8409:
8407:
8404:
8402:
8399:
8397:
8394:
8392:
8389:
8387:
8386:Guinea-Bissau
8384:
8382:
8379:
8373:
8370:
8369:
8368:impact
8367:
8365:
8362:
8358:
8355:
8351:
8348:
8346:
8343:
8342:
8340:
8339:
8337:
8336:
8335:
8332:
8330:
8327:
8325:
8322:
8320:
8317:
8315:
8312:
8310:
8307:
8306:
8304:
8300:
8294:
8291:
8289:
8286:
8284:
8281:
8279:
8276:
8274:
8271:
8269:
8266:
8264:
8261:
8260:
8258:
8254:
8248:
8245:
8243:
8240:
8236:
8233:
8232:
8231:
8228:
8226:
8223:
8221:
8218:
8216:
8213:
8211:
8208:
8206:
8203:
8201:
8198:
8196:
8193:
8192:
8190:
8186:
8180:
8177:
8175:
8172:
8170:
8167:
8165:
8162:
8158:
8155:
8154:
8153:
8150:
8148:
8145:
8143:
8140:
8138:
8135:
8133:
8130:
8128:
8125:
8123:
8120:
8118:
8115:
8113:
8110:
8108:
8105:
8103:
8100:
8098:
8095:
8093:
8090:
8089:
8087:
8083:
8075:
8072:
8071:
8070:
8067:
8065:
8062:
8060:
8057:
8055:
8052:
8050:
8047:
8045:
8042:
8040:
8037:
8035:
8032:
8030:
8027:
8025:
8022:
8020:
8017:
8016:
8014:
8010:
8007:
8003:
7999:
7994:
7992:
7989:
7988:
7987:
7986:
7985:
7981:
7977:
7973:
7968:
7964:
7950:
7947:
7945:
7942:
7941:
7939:
7935:
7929:
7926:
7924:
7921:
7917:
7914:
7913:
7912:
7909:
7905:
7902:
7901:
7900:
7897:
7893:
7890:
7889:
7888:
7885:
7881:
7878:
7877:
7876:
7873:
7869:
7866:
7865:
7864:
7861:
7857:
7854:
7853:
7852:
7849:
7845:
7842:
7841:
7840:
7837:
7833:
7830:
7829:
7828:
7825:
7821:
7818:
7817:
7816:
7813:
7809:
7806:
7805:
7804:
7801:
7800:
7798:
7794:
7786:
7783:
7782:
7781:
7778:
7774:
7771:
7770:
7769:
7766:
7762:
7759:
7758:
7757:
7754:
7750:
7747:
7746:
7745:
7742:
7738:
7735:
7734:
7733:
7730:
7726:
7723:
7722:
7721:
7718:
7714:
7711:
7710:
7709:
7706:
7702:
7699:
7698:
7697:
7694:
7690:
7687:
7686:
7685:
7682:
7678:
7675:
7674:
7673:
7670:
7666:
7663:
7662:
7661:
7658:
7654:
7651:
7650:
7649:
7646:
7645:
7643:
7639:
7631:
7628:
7627:
7626:
7623:
7619:
7616:
7615:
7614:
7611:
7607:
7604:
7603:
7602:
7599:
7595:
7592:
7591:
7590:
7587:
7583:
7580:
7579:
7578:
7575:
7571:
7568:
7567:
7566:
7563:
7559:
7556:
7555:
7554:
7551:
7547:
7544:
7543:
7542:
7539:
7535:
7532:
7531:
7530:
7527:
7523:
7520:
7519:
7518:
7515:
7511:
7508:
7507:
7506:
7503:
7499:
7496:
7495:
7494:
7491:
7490:
7488:
7484:
7478:
7475:
7473:
7470:
7468:
7465:
7463:
7460:
7458:
7455:
7452:
7449:
7446:
7443:
7442:
7440:
7438:
7434:
7430:
7426:
7421:
7417:
7410:
7409:
7405:
7402:
7401:
7397:
7396:
7393:
7389:
7382:
7377:
7375:
7370:
7368:
7363:
7362:
7359:
7343:
7341:
7338:
7337:
7335:
7332:
7329:
7326:
7324:
7321:
7320:
7316:
7310:
7307:
7305:
7302:
7300:
7297:
7295:
7292:
7291:
7289:
7285:
7279:
7276:
7274:
7273:
7269:
7267:
7264:
7262:
7259:
7257:
7254:
7252:
7249:
7246:
7244:
7239:
7236:
7234:
7231:
7230:
7228:
7224:
7218:
7217:Drew Weissman
7215:
7213:
7210:
7208:
7205:
7203:
7202:H. Fred Clark
7200:
7198:
7195:
7193:
7190:
7188:
7185:
7183:
7180:
7178:
7175:
7173:
7172:Louis Pasteur
7170:
7168:
7167:Edward Jenner
7165:
7164:
7162:
7156:
7144:
7141:
7139:
7138:DTwP-HepB-Hib
7136:
7134:
7133:DTaP-IPV-HepB
7131:
7129:
7126:
7125:
7124:combination:
7123:
7121:
7118:
7116:
7113:
7111:
7108:
7106:
7103:
7099:
7096:
7092:
7089:
7087:
7084:
7083:
7082:
7079:
7077:
7074:
7072:
7069:
7067:
7064:
7063:
7062:
7059:
7057:
7054:
7053:
7051:
7047:
7039:
7036:
7034:
7031:
7030:
7028:
7027:
7025:
7023:
7022:Helminthiasis
7019:
7011:
7008:
7007:
7005:
7001:
6998:
6997:
6996:
6993:
6992:
6990:
6986:
6978:
6975:
6973:
6970:
6968:
6965:
6963:
6960:
6958:
6955:
6953:
6950:
6948:
6945:
6944:
6942:
6938:
6935:
6933:
6930:
6928:
6925:
6924:
6923:combination:
6922:
6920:
6917:
6913:
6910:
6908:
6905:
6904:
6902:
6900:
6897:
6895:
6892:
6890:
6887:
6883:
6880:
6878:
6875:
6873:
6870:
6868:
6865:
6863:
6860:
6858:
6855:
6853:
6850:
6848:
6845:
6843:
6840:
6838:
6835:
6833:
6830:
6828:
6825:
6823:
6820:
6818:
6815:
6813:
6810:
6809:
6808:
6805:
6803:
6800:
6798:
6795:
6793:
6790:
6786:
6783:
6781:
6778:
6777:
6776:
6773:
6771:
6768:
6766:
6763:
6761:
6758:
6756:
6753:
6749:
6746:
6744:
6741:
6740:
6739:
6736:
6734:
6731:
6729:
6726:
6724:
6721:
6719:
6716:
6712:
6709:
6707:
6704:
6701:
6697:
6694:
6693:
6692:
6689:
6685:
6682:
6681:
6680:
6677:
6675:
6672:
6670:
6667:
6666:
6664:
6660:
6652:
6649:
6647:
6644:
6642:
6639:
6638:
6636:
6632:
6629:
6627:
6626:DPT/DTwP/DTaP
6624:
6623:
6622:combination:
6621:
6619:
6616:
6612:
6609:
6607:
6604:
6603:
6602:
6599:
6595:
6592:
6591:
6590:
6587:
6585:
6582:
6580:
6577:
6573:
6570:
6568:
6565:
6564:
6563:
6560:
6558:
6555:
6553:
6550:
6546:
6543:
6541:
6538:
6537:
6536:
6535:Meningococcus
6533:
6531:
6528:
6526:
6525:Leptospirosis
6523:
6521:
6518:
6516:
6513:
6511:
6508:
6506:
6503:
6501:
6498:
6497:
6495:
6491:
6488:
6484:
6476:
6473:
6471:
6468:
6466:
6463:
6461:
6460:Vaccine court
6458:
6456:
6453:
6452:
6450:
6446:
6443:
6441:
6438:
6436:
6433:
6431:
6428:
6426:
6423:
6421:
6418:
6416:
6415:GAVI Alliance
6413:
6412:
6410:
6409:
6407:
6403:
6397:
6394:
6392:
6389:
6387:
6383:
6380:
6378:
6374:
6370:
6366:
6363:
6359:
6356:
6354:
6351:
6350:
6348:
6346:
6343:
6341:
6338:
6337:
6335:
6331:
6325:
6322:
6320:
6317:
6315:
6312:
6310:
6307:
6303:
6300:
6299:
6298:
6295:
6293:
6290:
6289:
6287:
6283:
6278:
6274:
6270:
6266:
6262:
6258:
6254:
6247:
6242:
6240:
6235:
6233:
6228:
6227:
6224:
6217:
6213:
6210:
6209:
6205:
6203:
6199:
6194:
6190:
6186:
6181:
6177:
6173:
6169:
6165:
6161:
6157:
6153:
6141:
6137:
6136:
6131:
6127:
6126:
6121:
6120:
6112:
6090:
6086:
6081:
6076:
6072:
6068:
6067:
6062:
6058:
6054:
6050:
6046:
6042:
6038:
6034:
6030:
6026:
6022:
6018:
6014:
6011:(9): 318–24.
6010:
6006:
6005:
5997:
5992:
5991:
5970:
5966:
5962:
5956:
5940:
5936:
5935:
5930:
5923:
5907:
5903:
5902:
5897:
5890:
5882:
5878:
5873:
5868:
5864:
5860:
5856:
5852:
5848:
5841:
5839:
5822:
5818:
5814:
5808:
5806:
5797:
5793:
5788:
5783:
5778:
5773:
5769:
5765:
5761:
5754:
5746:
5742:
5738:
5734:
5730:
5726:
5723:(6): 885–99.
5722:
5718:
5711:
5709:
5700:
5696:
5691:
5686:
5682:
5680:9781555819200
5676:
5672:
5668:
5664:
5660:
5659:
5654:
5647:
5631:
5627:
5620:
5604:
5600:
5599:
5598:The Scientist
5594:
5587:
5585:
5576:
5572:
5568:
5564:
5560:
5556:
5552:
5548:
5541:
5525:
5521:
5520:
5515:
5508:
5492:
5488:
5487:
5482:
5475:
5459:
5455:
5451:
5445:
5429:
5422:
5416:
5414:
5397:
5393:
5389:
5382:
5380:
5363:
5359:
5353:
5345:
5341:
5336:
5331:
5327:
5323:
5320:(2): 446–55.
5319:
5315:
5311:
5304:
5296:
5292:
5288:
5284:
5280:
5276:
5273:(6): 562–65.
5272:
5268:
5261:
5253:
5249:
5245:
5239:
5235:
5231:
5227:
5220:
5212:
5208:
5203:
5198:
5194:
5190:
5186:
5182:
5178:
5171:
5155:
5151:
5147:
5140:
5124:
5120:
5119:
5114:
5107:
5099:
5095:
5091:
5087:
5083:
5079:
5075:
5068:
5066:
5064:
5055:
5051:
5046:
5041:
5037:
5033:
5029:
5025:
5021:
5014:
5006:
5002:
4997:
4992:
4988:
4984:
4980:
4973:
4965:
4961:
4956:
4951:
4947:
4943:
4939:
4935:
4931:
4924:
4916:
4912:
4907:
4902:
4897:
4892:
4888:
4884:
4880:
4873:
4857:
4853:
4849:
4842:
4826:
4822:
4818:
4811:
4795:
4791:
4787:
4780:
4778:
4776:
4759:
4755:
4751:
4744:
4742:
4725:
4721:
4717:
4710:
4708:
4691:
4687:
4683:
4676:
4668:
4664:
4659:
4654:
4650:
4646:
4642:
4638:
4634:
4630:
4626:
4619:
4603:
4599:
4595:
4588:
4586:
4577:
4573:
4568:
4563:
4559:
4555:
4552:(5): 319–34.
4551:
4547:
4543:
4536:
4520:
4516:
4515:
4510:
4503:
4501:
4499:
4490:
4486:
4481:
4476:
4471:
4466:
4462:
4458:
4454:
4447:
4445:
4436:
4432:
4428:
4424:
4420:
4416:
4412:
4408:
4400:
4392:
4388:
4383:
4378:
4375:(4): 627–36.
4374:
4370:
4366:
4359:
4351:
4347:
4343:
4339:
4335:
4331:
4327:
4323:
4315:
4299:
4295:
4291:
4285:
4277:
4273:
4268:
4263:
4259:
4255:
4251:
4244:
4236:
4232:
4228:
4224:
4220:
4216:
4213:(2): 161–76.
4212:
4208:
4201:
4193:
4189:
4184:
4179:
4175:
4171:
4167:
4163:
4159:
4155:
4151:
4144:
4142:
4133:
4121:
4113:
4109:
4105:
4099:
4095:
4091:
4087:
4080:
4072:
4068:
4063:
4058:
4053:
4048:
4044:
4040:
4036:
4029:
4027:
4025:
4023:
4021:
4019:
4017:
4000:
3996:
3992:
3985:
3977:
3973:
3968:
3963:
3958:
3953:
3949:
3945:
3941:
3934:
3926:
3922:
3917:
3912:
3908:
3904:
3900:
3896:
3892:
3885:
3883:
3873:
3868:
3864:
3860:
3857:(10): 17056.
3856:
3852:
3848:
3841:
3833:
3829:
3824:
3819:
3814:
3809:
3805:
3801:
3797:
3793:
3789:
3782:
3774:
3770:
3765:
3760:
3756:
3752:
3748:
3744:
3740:
3733:
3725:
3721:
3716:
3711:
3707:
3703:
3699:
3695:
3691:
3684:
3682:
3665:
3659:
3651:
3647:
3642:
3637:
3632:
3627:
3623:
3619:
3618:
3613:
3606:
3598:
3594:
3590:
3586:
3581:
3576:
3572:
3568:
3567:
3562:
3556:
3540:
3536:
3532:
3525:
3509:
3505:
3501:
3495:
3479:
3475:
3471:
3464:
3448:
3444:
3440:
3433:
3425:
3421:
3416:
3411:
3407:
3403:
3399:
3395:
3391:
3387:
3383:
3376:
3368:
3364:
3360:
3356:
3352:
3348:
3344:
3340:
3336:
3332:
3325:
3309:
3305:
3301:
3295:
3287:
3283:
3278:
3273:
3269:
3265:
3260:
3255:
3251:
3247:
3243:
3239:
3235:
3228:
3220:
3216:
3212:
3208:
3204:
3200:
3197:(11): 801–3.
3196:
3192:
3185:
3177:
3173:
3169:
3165:
3161:
3157:
3153:
3149:
3141:
3133:
3129:
3125:
3121:
3117:
3113:
3109:
3105:
3101:
3097:
3093:
3089:
3082:
3066:
3062:
3056:
3040:
3036:
3032:
3025:
3023:
3006:
3002:
2998:
2991:
2989:
2972:
2968:
2967:
2962:
2955:
2939:
2935:
2931:
2925:
2917:
2913:
2909:
2905:
2901:
2897:
2893:
2889:
2882:
2874:
2870:
2865:
2860:
2855:
2850:
2846:
2842:
2838:
2831:
2829:
2820:
2816:
2811:
2806:
2803:(2): 165–75.
2802:
2798:
2794:
2790:
2786:
2780:
2778:
2769:
2765:
2760:
2755:
2751:
2747:
2743:
2739:
2736:(3): 409–17.
2735:
2731:
2727:
2720:
2712:
2708:
2704:
2700:
2695:
2690:
2686:
2682:
2678:
2671:
2669:
2660:
2656:
2652:
2648:
2641:
2633:
2629:
2624:
2619:
2615:
2611:
2607:
2603:
2599:
2592:
2584:
2580:
2576:
2572:
2568:
2564:
2557:
2549:
2545:
2541:
2537:
2533:
2529:
2525:
2521:
2514:
2506:
2502:
2498:
2494:
2490:
2486:
2482:
2478:
2471:
2469:
2467:
2459:
2455:
2452:
2448:
2444:
2441:
2435:
2428:
2424:
2420:
2415:
2410:
2405:
2400:
2396:
2392:
2388:
2381:
2374:
2361:
2357:
2356:
2351:
2344:
2336:
2332:
2328:
2324:
2320:
2316:
2312:
2308:
2304:
2300:
2296:
2290:
2288:
2286:
2277:
2273:
2268:
2263:
2258:
2253:
2249:
2245:
2241:
2237:
2233:
2229:
2225:
2221:
2215:
2208:
2204:
2200:
2195:
2190:
2185:
2180:
2176:
2172:
2168:
2161:
2146:
2142:
2136:
2120:
2116:
2110:
2095:
2091:
2085:
2066:
2062:
2058:
2054:
2050:
2045:
2040:
2035:
2030:
2026:
2022:
2015:
2008:
1992:
1988:
1986:
1980:
1974:
1955:
1951:
1947:
1942:
1937:
1932:
1927:
1923:
1919:
1912:
1905:
1889:
1885:
1883:
1877:
1871:
1855:
1851:
1845:
1829:
1825:
1824:
1819:
1812:
1810:
1793:
1789:
1785:
1779:
1777:
1768:
1764:
1759:
1754:
1750:
1746:
1742:
1738:
1734:
1730:
1726:
1719:
1711:
1707:
1703:
1697:
1693:
1689:
1685:
1678:
1676:
1659:
1655:
1654:
1649:
1642:
1640:
1638:
1636:
1634:
1625:
1621:
1616:
1611:
1607:
1603:
1599:
1595:
1591:
1587:
1583:
1576:
1574:
1572:
1570:
1568:
1566:
1564:
1562:
1560:
1543:
1539:
1535:
1530:
1525:
1521:
1517:
1513:
1509:
1505:
1498:
1496:
1494:
1492:
1490:
1488:
1479:
1475:
1470:
1465:
1461:
1457:
1454:(4): 710–28.
1453:
1449:
1445:
1438:
1430:
1426:
1421:
1416:
1412:
1408:
1404:
1400:
1396:
1389:
1387:
1385:
1383:
1381:
1376:
1366:
1363:
1361:
1358:
1356:
1353:
1351:
1348:
1347:
1341:
1338:
1334:
1330:
1329:phase 1 trial
1326:
1325:Gritstone bio
1322:
1317:
1315:
1311:
1301:
1299:
1295:
1290:
1281:
1272:
1266:Amplification
1263:
1261:
1256:
1252:
1248:
1244:
1240:
1234:
1230:
1220:
1217:
1212:
1207:
1198:
1194:
1192:
1188:
1184:
1175:
1173:
1169:
1158:
1155:
1154:
1148:
1144:
1132:Disadvantages
1129:
1127:
1123:
1119:
1115:
1111:
1107:
1103:
1099:
1095:
1091:
1087:
1083:
1079:
1075:
1065:
1063:
1059:
1058:transcription
1053:
1050:
1045:
1043:
1040:, as well as
1039:
1035:
1026:
1012:
1010:
1006:
1002:
998:
997:model animals
994:
993:rhabdoviruses
990:
986:
982:
978:
974:
968:
958:
954:
952:
948:
947:microfluidics
943:
941:
937:
936:intravenously
933:
929:
925:
920:
915:
913:
909:
905:
896:
887:
885:
882:
879:is a natural
878:
874:
873:ribonucleases
870:
866:
857:
854:
850:
846:
836:
834:
830:
826:
822:
818:
817:into the skin
814:
809:
807:
803:
799:
798:
790:
785:
783:
779:
775:
770:
768:
764:
760:
754:
749:
747:
746:
741:
740:
734:
732:
728:
724:
720:
719:cell membrane
716:
707:
698:
696:
692:
688:
684:
680:
676:
672:
668:
664:
659:
657:
653:
649:
645:
641:
637:
633:
628:
626:
623:
619:
615:
611:
608:
607:
597:
588:
586:
582:
578:
574:
571:, where they
570:
566:
565:MHC molecules
562:
557:
555:
551:
546:
542:
538:
534:
530:
525:
523:
519:
515:
511:
507:
502:
500:
496:
492:
488:
480:
475:
470:
469:Immune system
460:
458:
455:
451:
446:
444:
440:
436:
432:
428:
424:
420:
416:
412:
408:
404:
400:
396:
392:
388:
383:
381:
377:
373:
369:
365:
361:
357:
353:
349:
339:
337:
333:
329:
325:
321:
316:
313:
309:
305:
304:biotechnology
301:
297:
294:in 2008, and
293:
289:
287:
283:
279:
275:
272:
271:
260:
258:
257:tumor antigen
254:
250:
246:
242:
238:
233:
231:
230:
225:
221:
212:
198:
196:
192:
191:Drew Weissman
188:
184:
180:
176:
172:
169:
165:
161:
157:
153:
149:
144:
142:
138:
134:
130:
126:
122:
118:
114:
93:
91:
87:
83:
79:
75:
71:
67:
63:
59:
55:
52:molecules of
51:
47:
46:messenger RNA
43:
40:is a type of
39:
36:
28:
23:
19:
18327:RNA vaccines
18248:
18176:Vatican City
17593:Saudi Arabia
17018:South Africa
17013:Sierra Leone
16889:Burkina Faso
16786:January 2021
16771:October 2020
16726:January 2020
16648:Ren Zhiqiang
16575:Chris Whitty
16509:Gregor Smith
16461:Saeed Namaki
16449:Doni Monardo
16443:Zweli Mkhize
16401:Tony Holohan
16383:Matt Hancock
16213:Zhang Jixian
16193:Wang Guangfa
16153:Shabir Madhi
16128:Matt Keeling
16078:Peter Daszak
15941:Relief funds
15495:Institutions
15323:Nirmatrelvir
15308:Molnupiravir
15250:Bebtelovimab
15240:Bamlanivimab
14772:South Africa
14692:Burkina Faso
14554:Viral vector
14531:(terminated)
14439:(terminated)
14418:(terminated)
14263:Viral vector
14207:EpiVacCorona
14159:
14047:Vaccine card
13887:Air purifier
13837:TCN Protocol
13792:NHS COVID-19
13777:Koronavilkku
13695:Aarogya Setu
13672:Surveillance
13621:Breathalyzer
13595:epidemiology
13515:Transmission
13267:curfew riots
12996:
12824:Mink farming
12812:ICU capacity
12558:Turkmenistan
12530:Human rights
12462:Social media
12427:Rugby league
12407:Gaelic games
12118:
12110:
12096:
12089:
12084:Cruise ships
11958:human rights
11907:Alert levels
11785:January–June
11714:Bougainville
11639:Cook Islands
11530:South Dakota
11520:Rhode Island
11508:Philadelphia
11503:Pennsylvania
11464:North Dakota
11012:Saint Martin
10951:Sint Maarten
10772:Saskatchewan
10548:Vatican City
10271:Saint Martin
10034:Transnistria
9811:January–June
9626:Saudi Arabia
9483:Soccsksargen
9468:Metro Manila
9453:Davao Region
9418:Bicol Region
9326:Kuala Lumpur
8921:Chhattisgarh
8657:Heilongjiang
8524:Turkmenistan
8485:January–June
8433:Sierra Leone
8341:2020
8314:Burkina Faso
8230:South Africa
7437:Pre-pandemic
7406:
7398:
7294:Epidemiology
7270:
7242:
7128:DTaP-IPV/Hib
6919:Yellow fever
6832:EpiVacCorona
6589:Tuberculosis
6562:Pneumococcal
6530:Lyme disease
6385:
6358:Heterologous
6257:Immunization
6215:
6206:
6188:
6159:
6144:. Retrieved
6140:the original
6133:
6116:RNA vaccine
6115:
6070:
6064:
6008:
6002:
5975:21 September
5973:. Retrieved
5964:
5955:
5945:21 September
5943:. Retrieved
5932:
5922:
5910:. Retrieved
5899:
5889:
5854:
5851:Gene Therapy
5850:
5825:. Retrieved
5816:
5767:
5763:
5753:
5720:
5716:
5662:
5656:
5646:
5634:. Retrieved
5619:
5607:. Retrieved
5596:
5550:
5546:
5540:
5528:. Retrieved
5517:
5507:
5495:. Retrieved
5484:
5474:
5462:. Retrieved
5458:the original
5453:
5444:
5432:. Retrieved
5400:. Retrieved
5391:
5366:. Retrieved
5352:
5317:
5313:
5303:
5270:
5266:
5260:
5226:RNA Vaccines
5225:
5219:
5187:(21): e142.
5184:
5180:
5170:
5158:. Retrieved
5149:
5139:
5127:. Retrieved
5116:
5106:
5073:
5027:
5023:
5013:
4989:(1): 55–59.
4986:
4982:
4972:
4940:(2): 82–93.
4937:
4933:
4923:
4886:
4882:
4872:
4860:. Retrieved
4851:
4841:
4829:. Retrieved
4820:
4810:
4798:. Retrieved
4789:
4762:. Retrieved
4753:
4728:. Retrieved
4719:
4694:. Retrieved
4685:
4675:
4632:
4629:Nano Letters
4628:
4618:
4606:. Retrieved
4597:
4549:
4545:
4535:
4523:. Retrieved
4512:
4460:
4456:
4410:
4406:
4399:
4372:
4368:
4358:
4325:
4322:Gene Therapy
4321:
4314:
4302:. Retrieved
4293:
4284:
4257:
4253:
4243:
4210:
4206:
4200:
4157:
4154:npj Vaccines
4153:
4085:
4079:
4045:(18): 6582.
4042:
4038:
4003:. Retrieved
3994:
3984:
3947:
3943:
3933:
3898:
3894:
3854:
3850:
3840:
3795:
3791:
3781:
3746:
3743:npj Vaccines
3742:
3732:
3697:
3693:
3668:. Retrieved
3658:
3621:
3615:
3605:
3570:
3564:
3555:
3543:. Retrieved
3534:
3524:
3512:. Retrieved
3503:
3494:
3482:. Retrieved
3473:
3463:
3451:. Retrieved
3442:
3432:
3389:
3385:
3375:
3334:
3330:
3324:
3312:. Retrieved
3303:
3294:
3241:
3237:
3227:
3194:
3190:
3184:
3151:
3147:
3140:
3091:
3087:
3081:
3069:. Retrieved
3055:
3043:. Retrieved
3034:
3009:. Retrieved
3000:
2975:. Retrieved
2964:
2954:
2942:. Retrieved
2933:
2924:
2894:(2): 180–8.
2891:
2887:
2881:
2844:
2840:
2800:
2796:
2733:
2729:
2719:
2684:
2680:
2650:
2646:
2640:
2608:(1): 10–31.
2605:
2601:
2591:
2566:
2562:
2556:
2523:
2519:
2513:
2480:
2476:
2440:WO1990011092
2434:
2426:
2397:(18): 6582.
2394:
2390:
2380:
2371:
2364:. Retrieved
2353:
2343:
2310:
2306:
2239:
2235:
2214:
2206:
2177:(18): 6582.
2174:
2170:
2160:
2148:. Retrieved
2144:
2135:
2123:. Retrieved
2118:
2109:
2097:. Retrieved
2093:
2084:
2072:. Retrieved
2024:
2020:
2007:
1995:. Retrieved
1982:
1973:
1961:. Retrieved
1921:
1917:
1904:
1892:. Retrieved
1879:
1870:
1858:. Retrieved
1844:
1832:. Retrieved
1823:The Guardian
1821:
1796:. Retrieved
1732:
1728:
1718:
1683:
1662:. Retrieved
1651:
1589:
1585:
1546:. Retrieved
1511:
1507:
1451:
1447:
1437:
1402:
1398:
1318:
1307:
1286:
1269:
1236:
1211:Margaret Liu
1208:
1204:
1195:
1181:
1178:Side effects
1164:
1151:
1140:
1100:is averted.
1094:cell nucleus
1074:DNA vaccines
1071:
1068:DNA vaccines
1054:
1046:
1031:
989:alphaviruses
985:lentiviruses
981:retroviruses
970:
961:Viral vector
955:
944:
931:
927:
916:
901:
863:
842:
828:
810:
805:
801:
795:
793:
788:
773:
771:
757:
752:
743:
737:
735:
712:
660:
631:
629:
604:
602:
558:
554:cell nucleus
537:phagocytosis
526:
518:viral vector
503:
484:
447:
439:Tuberculosis
389:, COVID-19,
384:
345:
342:Acceleration
317:
290:
268:
266:
234:
227:
224:nanoparticle
220:transfection
217:
145:
111:
58:immune cells
37:
34:
32:
26:
18:
18219:New Zealand
18120:cases chart
18108:cases chart
18103:Switzerland
18096:cases chart
18084:cases chart
18072:cases chart
18055:cases chart
18023:cases chart
18013:cases chart
18001:cases chart
17984:cases chart
17972:cases chart
17957:Netherlands
17925:cases chart
17915:cases chart
17888:cases chart
17876:cases chart
17864:cases chart
17842:cases chart
17830:cases chart
17813:cases chart
17796:cases chart
17769:cases chart
17752:cases chart
17735:cases chart
17688:cases chart
17676:cases chart
17664:cases chart
17652:cases chart
17608:cases chart
17603:South Korea
17576:cases chart
17549:cases chart
17544:Philippines
17537:cases chart
17525:cases chart
17513:cases chart
17496:cases chart
17479:cases chart
17452:cases chart
17430:cases chart
17418:cases chart
17401:cases chart
17389:cases chart
17342:by province
17327:cases chart
17310:cases chart
17293:cases chart
17281:by division
17249:Afghanistan
17189:cases chart
17164:El Salvador
17142:cases chart
17108:by province
17070:cases chart
17030:South Sudan
17023:cases chart
16991:cases chart
16936:Ivory Coast
16929:cases chart
16821:August 2021
16761:August 2020
16608:Chen Qiushi
16587:Jeff Zients
16583:(Singapore)
16565:(Argentina)
16527:Theresa Tam
16455:Alma Möller
16451:(Indonesia)
16437:Oriol Mitjà
16397:(Australia)
16389:Hamad Hasan
16274:By location
16168:Shi Zhengli
16133:Trudie Lang
16093:Dale Fisher
16045:Researchers
16020:Li Wenliang
15837:(Indonesia)
15807:(Australia)
15722:(Australia)
15709:By location
15615:(Sri Lanka)
15591:(Indonesia)
15574:(Australia)
15303:Ensitrelvir
15280:Tocilizumab
15260:Regdanvimab
15182:Baricitinib
15095:New Zealand
15004:Switzerland
14863:South Korea
14848:Philippines
14655:by location
14586:ImmunityBio
14561:AdCLD-CoV19
14474:EuCorVac-19
14373:Inactivated
14242:Soberana 02
14130:QazCovid-in
14087:Inactivated
14009:Development
13907:Evacuations
13827:StaySafe.ph
13787:MySejahtera
13762:Health Code
13747:Covid Watch
13725:COVID Alert
13593:Testing and
13461:Environment
13378:Anthropause
13274:New Zealand
13262:Netherlands
13030:Legislation
12985:Philippines
12960:Governments
12921:Information
12860:Chip supply
12761:By industry
12737:New Zealand
12553:North Korea
12354:Philippines
12242:Video games
12228:U.S. sports
12193:Corona-chan
12156:Culture and
12105:Naval ships
11864:New Zealand
11781:2021
11587:White House
11515:Puerto Rico
11393:Mississippi
11277:Connecticut
11216:By location
11088:vaccination
11063:El Salvador
11028:Puerto Rico
10864:Saint Lucia
10741:Vaccination
10731:York Region
10721:Peel Region
10681:Nova Scotia
10627:by province
10622:vaccination
10615:federal aid
10526:Microstates
10517:Switzerland
10384:Netherlands
10340:vaccination
9938:Isle of Man
9793:By location
9631:vaccination
9408:vaccination
9396:evacuations
9351:Philippines
9214:vaccination
9192:vaccination
9080:West Bengal
9075:Uttarakhand
9005:Maharashtra
8995:Lakshadweep
8884:By location
8868:vaccination
8827:January–May
8801:evacuations
8730:Afghanistan
8640:vaccination
8583:South Korea
8578:North Korea
8391:Ivory Coast
8169:South Sudan
7330:from market
7226:Controversy
7160:researchers
7076:Hepatitis B
6962:Hepatitis C
6907:Chicken pox
6733:Hepatitis E
6728:Hepatitis B
6723:Hepatitis A
6674:Chikungunya
6651:Shigellosis
6505:Brucellosis
6391:Therapeutic
6345:Inactivated
6285:Development
6273:Inoculation
6265:Vaccination
6146:17 November
6118:(Q85795487)
5636:10 December
5609:27 November
5530:21 November
5497:21 November
5464:18 November
5434:21 December
5402:18 November
5368:17 December
5160:28 February
5129:28 November
4800:24 February
4792:. Gannett.
4686:MarketWatch
4369:RNA Biology
4304:20 December
3895:RNA Biology
3484:21 December
3314:26 November
2977:16 November
1997:21 December
1860:10 December
1664:18 November
1350:DNA vaccine
1126:replication
973:RNA viruses
778:endocytosis
683:codon usage
667:nucleotides
638:. It has a
610:transcribed
569:lymph nodes
561:proteasomes
514:inactivated
427:henipaviral
415:Lassa fever
308:US military
263:Development
129:genomic DNA
74:cancer cell
68:(such as a
18321:Categories
18040:San Marino
18033:North Asia
17952:Montenegro
17932:Luxembourg
17683:Uzbekistan
17642:Tajikistan
17586:North Asia
17459:Kyrgyzstan
17442:Kazakhstan
17364:East Timor
17276:Bangladesh
17266:Azerbaijan
17137:Costa Rica
17125:by commune
17008:Seychelles
16976:Mozambique
16961:Mauritania
16801:April 2021
16796:March 2021
16741:April 2020
16736:March 2020
16511:(Scotland)
16481:(Malaysia)
16419:Li Keqiang
16379:(Portugal)
16373:(Portugal)
16307:(Thailand)
16295:(Scotland)
16208:Zeng Guang
16148:Ma Xiaowei
16138:Li Lanjuan
16103:Azra Ghani
15855:(Malaysia)
15798:institutes
15750:institutes
15671:(Scotland)
15657:North West
15652:North East
15642:Birmingham
15603:(Malaysia)
15313:Remdesivir
15270:Sotrovimab
15244:Etesevimab
15142:Antarctica
14833:Kazakhstan
14793:Bangladesh
14707:Cape Verde
14653:Deployment
14634:MigVax-101
14514:Skycovione
14494:Sanofi–GSK
14330:Attenuated
14271:Convidecia
14061:Authorized
14004:Deployment
13969:Zero-COVID
13912:Face masks
13880:Prevention
13847:Thai Chana
13832:SwissCovid
13542:Long COVID
13433:Zoom towns
13423:Zero-COVID
13403:Quarantini
13398:Long COVID
13103:Azerbaijan
12992:Ivermectin
12932:Journalism
12703:By country
12446:and rights
12422:Motorsport
12417:Ice hockey
12380:Basketball
12342:By country
12278:By country
12218:Television
12079:Antarctica
12041:statistics
11987:statistics
11953:statistics
11834:Queensland
11577:Washington
11435:New Mexico
11430:New Jersey
11255:California
11058:Costa Rica
11002:Martinique
10997:Guadeloupe
10914:Montserrat
10543:San Marino
10374:Luxembourg
10256:Martinique
10241:Guadeloupe
10143:statistics
10128:Montenegro
10095:Sevastopol
10019:Kazakhstan
9523:Azerbaijan
9448:Cordillera
9428:Calabarzon
9413:Bangsamoro
9316:statistics
9219:statistics
9197:statistics
9120:East Timor
9055:Tamil Nadu
9035:Puducherry
8916:Chandigarh
8816:statistics
8735:Bangladesh
8635:statistics
8529:Uzbekistan
8519:Tajikistan
8472:Kyrgyzstan
8467:Kazakhstan
8345:March–July
8319:Cape Verde
8220:Mozambique
8164:Somaliland
8147:Seychelles
8122:Madagascar
8044:Mauritania
7408:SARS-CoV-2
7261:Thiomersal
7207:Paul Offit
7182:Jonas Salk
7158:Inventors/
7029:research:
7006:research:
6943:research:
6872:Skycovione
6862:Sanofi–GSK
6807:SARS-CoV-2
6718:Hantavirus
6684:rVSV-ZEBOV
6669:Adenovirus
6637:research:
6515:Diphtheria
6353:Attenuated
5770:(4): 122.
5360:. Pfizer.
4889:(3): 189.
4696:5 February
4525:3 December
4005:28 January
3700:: 168–89.
3624:(3): 636.
3453:2 December
3148:The Lancet
3035:BioCentury
2789:Weissman D
2303:Felgner PL
2224:Felgner PL
2074:7 February
1963:7 February
1894:6 February
1834:2 December
1798:2 December
1548:8 December
1514:: 100766.
1508:Nano Today
1405:: 137–51.
1371:References
1337:SARS‑CoV‑2
1251:SARS-CoV-2
1247:Retrovirus
1086:translated
1015:Advantages
977:engineered
975:have been
869:polyplexes
833:lymph node
815:, such as
721:by simple
646:(UTR) and
510:attenuated
491:antibodies
489:to create
429:diseases,
364:in history
352:SARS-CoV-2
328:Zika virus
72:) or by a
18192:Australia
18167:by nation
18152:Gibraltar
18060:by region
17920:Lithuania
17620:Sri Lanka
17598:Singapore
17384:Indonesia
17347:Hong Kong
17337:lockdowns
17233:Venezuela
17196:Nicaragua
17169:Guatemala
17088:Argentina
16966:Mauritius
16852:Lockdowns
16816:July 2021
16811:June 2021
16756:July 2020
16751:June 2020
16623:Fang Fang
16571:(Romania)
16559:(Iceland)
16541:(Iceland)
16515:Su Ih-jen
16493:(Uruguay)
16485:Ali Pilli
16475:(Vietnam)
16469:(Moldova)
16457:(Iceland)
16439:(Andorra)
16403:(Ireland)
16395:Greg Hunt
16391:(Lebanon)
16349:(Germany)
16325:(Romania)
16232:Officials
16188:Wang Chen
16183:John Todd
16030:Xie Linka
15933:(Uruguay)
15843:(Ireland)
15458:Cluster 5
15328:ritonavir
15265:Sarilumab
15160:Treatment
15111:Argentina
15085:Australia
14868:Sri Lanka
14858:Singapore
14813:Indonesia
14601:NDV-HXP-S
14581:GRAd-COV2
14535:Vabiotech
14484:Nanocovax
14427:mRNA-1283
14385:NDV-HXP-S
14322:In trials
14286:Sputnik V
14254:(Zifivax)
14120:FAKHRAVAC
14100:CoronaVac
13944:Lockdowns
13817:SafeEntry
13807:PathCheck
13737:COVIDSafe
13700:BlueTrace
13569:Shortages
13559:Pregnancy
13454:Cluster 5
13418:Twindemic
13091:Australia
13086:Argentina
12998:Plandemic
12908:Inflation
12855:Shortages
12807:Hospitals
12543:Hong Kong
12538:Argentina
12402:Disc golf
12252:Education
12063:Venezuela
11975:São Paulo
11948:Argentina
11766:Australia
11599:Wisconsin
11535:Tennessee
11388:Minnesota
11337:Louisiana
11162:responses
11095:Nicaragua
11068:Guatemala
10800:Countries
10793:Caribbean
10584:Greenland
10369:Lithuania
10352:lockdowns
9970:Gibraltar
9782:education
9762:contracts
9740:responses
9616:Palestine
9269:political
9162:Singapore
9125:Indonesia
9098:Southeast
9060:Telangana
9045:Rajasthan
9015:Meghalaya
8973:Karnataka
8968:Jharkhand
8774:Sri Lanka
8549:Hong Kong
8510:political
8372:education
8127:Mauritius
7998:responses
7972:Locations
7916:responses
7904:responses
7899:September
7892:responses
7880:responses
7868:responses
7856:responses
7844:responses
7832:responses
7820:responses
7808:responses
7785:responses
7773:responses
7761:responses
7749:responses
7744:September
7737:responses
7725:responses
7713:responses
7701:responses
7689:responses
7677:responses
7665:responses
7653:responses
7630:responses
7618:responses
7606:responses
7594:responses
7589:September
7582:responses
7570:responses
7558:responses
7546:responses
7534:responses
7522:responses
7510:responses
7498:responses
7467:Event 201
7462:Disease X
7403:(disease)
7340:Phase III
7328:Withdrawn
7256:Pox party
7066:ALVAC-CEA
6988:Protozoan
6877:Sputnik V
6827:CoronaVac
6797:Rotavirus
6700:Pandemrix
6552:Pertussis
6493:Bacterial
6377:Synthetic
6340:Conjugate
6292:Adjuvants
6269:Infection
6216:Star Wars
6041:237515383
5575:227180967
5098:227176634
4790:USA Today
4463:(1): 33.
4174:2059-0105
4160:(1): 11.
4130:ignored (
4120:cite book
3950:(1): 20.
3749:(1): 28.
3597:259184146
3406:1078-0432
3367:229324351
3268:2058-8437
3219:238637957
3132:237515383
3116:0028-0836
2934:France 24
2847:(2): 97.
2750:0021-9738
2703:1474-1784
2299:Malone RW
2220:Malone RW
2150:3 October
2125:3 October
2099:3 October
2061:229945697
1749:0022-3549
1606:1474-1784
1538:202221207
1223:Hesitancy
1147:mRNA-1273
1049:mRNA-1273
877:Protamine
813:injection
723:diffusion
715:cytoplasm
675:half-life
550:cytoplasm
541:ribosomes
522:transgene
463:Mechanism
324:influenza
312:pandemics
245:replicase
82:delivered
18311:COVID-19
18287:Medicine
18067:Slovenia
18050:Slovakia
17996:Portugal
17764:Bulgaria
17647:Thailand
17532:Pakistan
17474:Malaysia
17305:Cambodia
17221:by state
17206:Paraguay
17179:Honduras
17132:Colombia
17081:Americas
17065:Zimbabwe
17040:Tanzania
16919:Ethiopia
16914:Eswatini
16899:Cameroon
16884:Botswana
16806:May 2021
16746:May 2020
16633:Li Zehua
16618:Fang Bin
16547:(Greece)
16535:(Sweden)
16529:(Canada)
16523:(Poland)
16517:(Taiwan)
16499:(France)
16427:(Mexico)
16415:(Turkey)
16319:(Taiwan)
16313:(Taiwan)
16301:(Taiwan)
16063:Chen Wei
15879:(Turkey)
15873:(Taiwan)
15819:(Canada)
15813:(Canada)
15796:Pandemic
15788:(Taiwan)
15728:(Canada)
15627:(Turkey)
15621:(Turkey)
15440:timeline
15368:Specific
15357:Variants
15121:Colombia
15067:mandates
14979:Portugal
14919:Bulgaria
14878:Thailand
14838:Malaysia
14777:Zimbabwe
14747:Eswatini
14732:Djibouti
14712:Cameroon
14702:Cameroon
14687:Botswana
14639:VBI-2902
14596:INNA-051
14591:iNCOVACC
14504:SCB-2019
14499:S-268019
14411:Bangavax
14406:ARCT-154
14401:ARCT-021
14202:COVAX-19
14196:Corbevax
14145:Turkovac
13979:Vaccines
13862:Valtrace
13822:SafePass
13727:(Canada)
13705:careFIJI
13667:Software
13606:Datasets
13520:Symptoms
13466:Military
13370:Language
13286:Paraguay
13257:Mongolia
13174:Colombia
13135:Bulgaria
13081:Abkhazia
13073:Protests
13058:Malaysia
13013:Politics
12773:Airlines
12768:Aviation
12732:Malaysia
12672:Economic
12645:Religion
12603:Minority
12477:Children
12375:Baseball
12363:By sport
12166:Arts and
12053:Suriname
12031:Paraguay
12004:timeline
11999:Colombia
11849:Victoria
11844:Tasmania
11674:Kiribati
11572:Virginia
11545:timeline
11496:Portland
11486:Oklahoma
11479:Columbus
11450:timeline
11440:New York
11418:timeline
11408:Nebraska
11398:Missouri
11383:Michigan
11374:timeline
11364:timeline
11352:timeline
11347:Maryland
11332:Kentucky
11312:Illinois
11282:Delaware
11272:Colorado
11260:timeline
11250:Arkansas
11083:timeline
11073:Honduras
10924:response
10899:Anguilla
10879:timeline
10834:Dominica
10817:Barbados
10777:timeline
10763:boroughs
10758:Montreal
10661:Manitoba
10649:timeline
10605:timeline
10572:Atlantic
10510:Svalbard
10438:Asturias
10433:timeline
10423:Slovenia
10418:Slovakia
10411:timeline
10401:Portugal
10357:timeline
10266:Normandy
10183:timeline
10173:Bulgaria
10078:timeline
10029:Gagauzia
9948:Guernsey
9879:Scotland
9777:economic
9752:response
9648:timeline
9562:Abkhazia
9473:Mimaropa
9341:Selangor
9264:economic
9248:Malaysia
9231:timeline
9209:timeline
9204:Thailand
9115:Cambodia
9025:Nagaland
8983:timeline
8806:lockdown
8762:Pakistan
8752:Maldives
8740:timeline
8704:Xinjiang
8682:Shanghai
8677:Liaoning
8623:lockdown
8593:Mongolia
8559:timeline
8500:economic
8263:Cameroon
8247:Zimbabwe
8205:Eswatini
8200:Botswana
8188:Southern
8174:Tanzania
8157:Puntland
8112:Ethiopia
8102:Djibouti
8012:Northern
7996:national
7991:timeline
7928:December
7923:November
7815:February
7780:December
7768:November
7660:February
7625:December
7613:November
7505:February
7425:Timeline
7400:COVID-19
7098:Prostvac
7091:Gardasil
7086:Cervarix
7033:Hookworm
6912:Shingles
6894:Smallpox
6812:Corbevax
6748:Gardasil
6743:Cervarix
6486:Vaccines
6440:Schedule
6411:Global:
6319:Timeline
6261:Vaccines
6212:webcomic
6089:25233993
6057:Türeci Ö
6053:Karikó K
6033:34522017
5969:Archived
5939:Archived
5906:Archived
5881:33093657
5821:Archived
5796:31547081
5764:Vaccines
5745:33489182
5737:24665982
5699:25844274
5630:Archived
5603:Archived
5567:33243869
5524:Archived
5491:Archived
5428:Archived
5396:Archived
5362:Archived
5344:29275847
5295:38532700
5252:27987145
5211:21890902
5154:Archived
5150:CTV News
5123:Archived
5090:33239758
5054:21987744
5005:11112481
4983:Virology
4964:25419577
4915:30832256
4856:Archived
4825:Archived
4794:Archived
4758:Archived
4730:26 March
4724:Archived
4690:Archived
4667:29489381
4602:Archived
4576:27075952
4519:Archived
4489:33593376
4427:19609242
4391:21654214
4350:27518606
4342:17476302
4298:Archived
4276:21045153
4235:38292712
4227:25196947
4192:32047656
4112:28101688
4071:32916818
3999:Archived
3976:33933145
3925:23064118
3832:31323032
3773:33619260
3724:33316346
3670:26 April
3650:36992220
3641:10057252
3617:Vaccines
3589:37328586
3545:15 March
3539:Archived
3514:15 March
3508:Archived
3478:Archived
3447:Archived
3443:BBC News
3424:33542081
3359:33340018
3308:Archived
3286:34394960
3211:34635829
3168:28754494
3124:34522017
3065:Archived
3039:Archived
3005:Archived
2971:Archived
2938:Archived
2908:18481387
2873:33525396
2841:Vaccines
2819:16111635
2797:Immunity
2785:Karikó K
2768:11828001
2711:25233993
2632:24757523
2548:42640967
2505:19350848
2497:15268662
2454:Archived
2443:Archived
2438:Patent:
2423:32916818
2360:Archived
2295:Wolff JA
2228:Verma IM
2203:32916818
2065:Archived
2053:33382675
1991:Archived
1954:Archived
1950:33332292
1888:Archived
1854:Archived
1828:Archived
1792:Archived
1767:33321139
1710:27987140
1658:Archived
1624:29326426
1542:Archived
1478:30846391
1448:Mol Ther
1429:33340620
1344:See also
1201:Efficacy
1143:BNT162b2
1078:vaccines
1034:vaccines
1009:primates
999:such as
932:in vitro
912:Onpattro
881:cationic
845:delivery
797:in vitro
763:surfaces
701:Delivery
632:in vitro
622:T7 phage
606:in vitro
585:immunity
545:degrades
535:through
506:antigens
499:antigens
495:pathogen
454:melanoma
452:against
292:BioNTech
229:in vitro
121:cellular
66:pathogen
50:delivers
27:in vitro
18299:Viruses
18273:Portals
18185:Oceania
18127:Ukraine
18008:Romania
17942:Moldova
17871:Ireland
17859:Iceland
17854:Hungary
17837:Germany
17820:Finland
17808:Estonia
17791:Denmark
17776:Croatia
17747:Belgium
17742:Belarus
17730:Austria
17725:Albania
17695:Vietnam
17501:summary
17491:Myanmar
17469:Lebanon
17374:Georgia
17315:summary
17271:Bahrain
17259:Artsakh
17254:Armenia
17228:Uruguay
17159:Ecuador
17093:Bolivia
17050:Tunisia
17003:Senegal
16981:Namibia
16904:Comoros
16894:Burundi
16869:Algeria
16855:<
16553:(India)
16505:(Spain)
16421:(China)
16367:(Italy)
16331:(Italy)
16283:(Wales)
16113:Guan Yi
16025:Liu Wen
16001:Medical
15956:(India)
15950:(India)
15849:(Japan)
15831:(India)
15823:PREPARE
15765:(Ghana)
15734:(China)
15677:(Wales)
15585:(India)
15451:General
15435:Omicron
15395:Epsilon
15078:Oceania
15035:Ontario
15009:Ukraine
14984:Romania
14969:Moldova
14959:Ireland
14954:Iceland
14949:Hungary
14939:Germany
14929:Denmark
14924:Croatia
14909:Albania
14893:Vietnam
14767:Senegal
14762:Nigeria
14757:Morocco
14722:Comoros
14697:Burundi
14672:Algeria
14624:ABNCoV2
14571:COH04S1
14566:BriLife
14509:SCTV01C
14479:IVX-411
14469:AKS-452
14464:202-CoV
14457:Subunit
14416:CureVac
14276:Janssen
14227:Novavax
14212:IndoVac
14183:Subunit
14168:Moderna
14150:Valneva
14105:Covaxin
14077:ZyCoV-D
13449:Animals
13296:Tunisia
13223:Germany
13113:Belgium
13108:Belarus
13053:Ireland
12839:Tourism
12720:Ireland
12589:Prisons
12548:Myanmar
12520:Strikes
12444:Society
12397:Cricket
12349:Ireland
12290:Ireland
12058:Uruguay
12011:Ecuador
11965:Bolivia
11940:America
11751:Vanuatu
11736:Tokelau
11622:Oceania
11604:Wyoming
11567:Vermont
11403:Montana
11317:Indiana
11292:Georgia
11287:Florida
11238:Arizona
11223:Alabama
10967:Bonaire
10946:Curaçao
10854:Jamaica
10844:Grenada
10812:Bahamas
10726:Toronto
10691:Ontario
10686:Nunavut
10644:Alberta
10579:Bermuda
10564:America
10533:Andorra
10495:Iceland
10458:Melilla
10406:Romania
10305:Ireland
10300:Hungary
10278:Germany
10261:Mayotte
10251:Réunion
10224:Finland
10219:Estonia
10207:Denmark
10178:Croatia
10168:Belgium
10163:Austria
10113:Albania
10085:Ukraine
10024:Moldova
9992:Belarus
9985:Eastern
9800:England
9695:history
9606:Lebanon
9557:Georgia
9535:Bahrain
9528:Artsakh
9518:Armenia
9336:Sarawak
9226:Vietnam
9157:Myanmar
9065:Tripura
9020:Mizoram
9010:Manipur
8953:Haryana
8948:Gujarat
8694:Sichuan
8645:Beijing
8428:Senegal
8411:Nigeria
8396:Liberia
8302:Western
8256:Central
8225:Namibia
8210:Lesotho
8152:Somalia
8137:Réunion
8132:Mayotte
8107:Eritrea
8097:Comoros
8092:Burundi
8085:Eastern
8064:Tunisia
8054:Morocco
8049:Melilla
8019:Algeria
7911:October
7803:January
7756:October
7648:January
7601:October
7493:January
7411:(virus)
7287:Related
7233:General
6995:Malaria
6882:Valneva
6847:Novavax
6842:Moderna
6837:Janssen
6822:CanSino
6802:Rubella
6760:Measles
6631:Td/Tdap
6601:Typhoid
6584:Tetanus
6579:Q fever
6510:Cholera
6500:Anthrax
6369:Peptide
6333:Classes
6314:Storage
6202:YouTube
6135:Horizon
6111:Scholia
6049:Sahin U
6013:Bibcode
5872:7580817
5827:6 April
5787:6963228
5690:4383315
5547:Science
5454:NPR.org
5392:NPR.org
5335:5835025
5287:9624688
5202:3241667
5045:3218670
4955:4326030
4906:6471356
4862:7 March
4831:3 April
4764:3 April
4658:6054134
4637:Bibcode
4608:6 March
4567:5439223
4480:7884263
4435:3278811
4183:7000814
4062:7554980
3967:8087878
3916:3597572
3859:Bibcode
3823:6668849
3800:Bibcode
3764:7900244
3715:7733686
3535:Reuters
3415:8052930
3339:Bibcode
3277:8353930
3246:Bibcode
3176:7700297
3096:Bibcode
3045:19 June
3011:21 June
2944:31 July
2916:8233422
2864:7911542
2659:7882341
2623:3991152
2583:7879415
2563:Vaccine
2540:8325342
2414:7554980
2366:31 July
2335:1690918
2315:Bibcode
2307:Science
2276:2762315
2244:Bibcode
2194:7554980
2119:Reuters
2044:9191904
1941:7745957
1758:7834447
1615:5906799
1469:6453548
1420:7744276
1294:uridine
1239:cytosol
1137:Storage
1090:cytosol
1088:in the
1005:chicken
928:in vivo
884:peptide
829:in vivo
825:muscles
806:ex vivo
802:in vivo
789:In vivo
774:ex vivo
767:T cells
753:Ex vivo
745:ex vivo
739:in vivo
731:RNAases
614:plasmid
581:B cells
577:T cells
407:Malaria
296:Moderna
270:ex vivo
249:humoral
241:T cells
237:antigen
201:History
160:Moderna
62:protein
54:antigen
42:vaccine
38:vaccine
18238:Others
18115:Turkey
18091:Sweden
18045:Serbia
18018:Russia
17979:Poland
17967:Norway
17947:Monaco
17910:Latvia
17905:Kosovo
17849:Greece
17825:France
17781:Cyprus
17717:Europe
17659:Turkey
17630:Taiwan
17571:Russia
17484:charts
17447:Kuwait
17437:Jordan
17413:Israel
17359:Cyprus
17300:Brunei
17288:Bhutan
17201:Panama
17184:Mexico
17103:Canada
17098:Brazil
17060:Zambia
17055:Uganda
16986:Nigera
16951:Malawi
16874:Angola
16862:Africa
16828:deaths
16696:Global
16657:Deaths
16601:Others
16463:(Iran)
16010:Ai Fen
15991:People
15748:Health
15698:Global
15647:London
15560:Others
15425:Lambda
15135:Others
15116:Brazil
15057:Mexico
15040:Quebec
15030:Canada
14999:Sweden
14989:Russia
14974:Norway
14944:Greece
14934:France
14902:Europe
14883:Turkey
14873:Taiwan
14853:Russia
14823:Israel
14798:Bhutan
14677:Angola
14664:Africa
14629:LYB001
14519:UB-612
14448:Walvax
14422:HGC019
14380:KD-414
14364:Inovio
14252:ZF2001
14191:Abdala
14125:Minhai
14038:(U.S.)
13987:Topics
13772:Immuni
13527:Cancer
13442:Others
13291:Serbia
13240:Israel
13235:Greece
13196:France
13140:Canada
13118:Brazil
13063:Russia
12980:Canada
12865:Energy
12834:Retail
12742:Russia
12710:Canada
12610:Gender
12467:Stigma
12321:Sports
12198:Disney
12181:Cinema
12145:Impact
12072:Others
12026:Guyana
11970:Brazil
11746:Tuvalu
11669:Hawaii
11550:Austin
11491:Oregon
11413:Nevada
11369:Boston
11327:Kansas
11302:Hawaii
11228:Alaska
11100:Panama
11078:Mexico
11053:Belize
10753:Quebec
10716:Ottawa
10598:Canada
10538:Monaco
10505:Norway
10465:Sweden
10396:Poland
10364:Latvia
10295:Greece
10236:France
10190:Cyprus
10138:Serbia
10123:Kosovo
10090:Crimea
10073:Turkey
10041:Russia
9943:Jersey
9835:London
9772:social
9674:Europe
9643:Turkey
9601:Kuwait
9596:Jordan
9591:Israel
9540:Cyprus
9433:Caraga
9259:social
9110:Brunei
9050:Sikkim
9040:Punjab
9030:Odisha
8990:Ladakh
8978:Kerala
8747:Bhutan
8628:detail
8598:Taiwan
8505:social
8477:Russia
8381:Guinea
8329:Gambia
8242:Zambia
8215:Malawi
8195:Angola
8179:Uganda
8142:Rwanda
7984:Africa
7887:August
7732:August
7577:August
7453:(MERS)
7447:(SARS)
7323:WHO-EM
7243:Lancet
7120:TA-NIC
7105:NicVAX
6952:Dengue
6792:Rabies
6618:Typhus
6557:Plague
6435:Policy
6396:Toxoid
6324:Trials
6087:
6039:
6031:
6004:Nature
5879:
5869:
5794:
5784:
5743:
5735:
5697:
5687:
5677:
5573:
5565:
5342:
5332:
5293:
5285:
5250:
5240:
5209:
5199:
5096:
5088:
5052:
5042:
5003:
4962:
4952:
4913:
4903:
4665:
4655:
4574:
4564:
4487:
4477:
4433:
4425:
4389:
4348:
4340:
4274:
4233:
4225:
4190:
4180:
4172:
4110:
4100:
4069:
4059:
3974:
3964:
3923:
3913:
3830:
3820:
3771:
3761:
3722:
3712:
3648:
3638:
3595:
3587:
3422:
3412:
3404:
3365:
3357:
3331:Nature
3284:
3274:
3266:
3217:
3209:
3174:
3166:
3130:
3122:
3114:
3088:Nature
3071:31 May
2914:
2906:
2871:
2861:
2817:
2766:
2759:150859
2756:
2748:
2709:
2701:
2657:
2630:
2620:
2581:
2546:
2538:
2503:
2495:
2421:
2411:
2355:Nature
2333:
2274:
2267:297778
2264:
2201:
2191:
2059:
2051:
2041:
1948:
1938:
1765:
1755:
1747:
1708:
1698:
1622:
1612:
1604:
1536:
1476:
1466:
1427:
1417:
1243:RNAses
1161:Recent
1153:Nature
1098:genome
924:ligand
910:drug,
691:codons
648:3'-UTR
640:5' cap
395:Dengue
334:, and
320:rabies
18162:daily
18079:Spain
17937:Malta
17883:Italy
17707:Yemen
17625:Syria
17566:Qatar
17508:Nepal
17425:Japan
17379:India
17369:Egypt
17352:Macau
17322:China
17174:Haiti
17120:Chile
17035:Sudan
16946:Libya
16941:Kenya
16924:Ghana
16909:Egypt
16879:Benin
16840:China
16721:cases
15420:Kappa
15410:Theta
15390:Delta
15385:Gamma
15375:Alpha
15218:(WHO)
15052:Haiti
14994:Spain
14964:Italy
14843:Nepal
14828:Japan
14808:India
14752:Ghana
14737:Egypt
14682:Benin
14489:ReCOV
14359:GX-19
14309:CoVLP
14222:Noora
13336:Italy
13252:Italy
13157:China
13152:Chile
12965:China
12715:India
12579:Crime
12567:Legal
12498:Labor
12285:Ghana
12046:Cusco
11982:Chile
11938:South
11741:Tonga
11726:Samoa
11704:Palau
11684:Nauru
11540:Texas
11342:Maine
11307:Idaho
10941:Aruba
10849:Haiti
10784:Yukon
10562:North
10448:Ceuta
10428:Spain
10379:Malta
10347:Italy
10229:Åland
9906:Wales
9660:Yemen
9638:Syria
9621:Qatar
9552:Egypt
9389:Luzon
9331:Sabah
9321:Johor
8931:Delhi
8911:Bihar
8906:Assam
8784:India
8757:Nepal
8718:South
8699:Tibet
8667:Hubei
8662:Henan
8588:Macau
8564:Tokyo
8554:Japan
8406:Niger
8334:Ghana
8309:Benin
8288:Gabon
8117:Kenya
8059:Sudan
8039:Libya
8034:Egypt
8029:Ceuta
7839:April
7827:March
7684:April
7672:March
7529:April
7517:March
7251:NCVIA
7115:TA-CD
7049:Other
7000:RTS,S
6780:Sabin
6775:Polio
6770:Mumps
6679:Ebola
6662:Viral
6611:ViCPS
6606:Ty21a
6540:MeNZB
6470:VAERS
6420:NITAG
6349:Live
6037:S2CID
5999:(PDF)
5912:7 May
5741:S2CID
5571:S2CID
5424:(PDF)
5291:S2CID
5094:S2CID
4883:Genes
4431:S2CID
4346:S2CID
4231:S2CID
3995:Scope
3593:S2CID
3363:S2CID
3215:S2CID
3172:S2CID
3128:S2CID
2912:S2CID
2544:S2CID
2501:S2CID
2068:(PDF)
2057:S2CID
2017:(PDF)
1987:(FDA)
1983:U.S.
1957:(PDF)
1914:(PDF)
1884:(FDA)
1880:U.S.
1534:S2CID
1296:with
919:lipid
908:siRNA
823:, or
821:blood
693:with
650:, an
508:, an
423:Nipah
374:gave
300:DARPA
168:first
70:virus
25:mRNA
18204:Fiji
18145:2021
18140:2020
17520:Oman
17464:Laos
17408:Iraq
17396:Iran
17242:Asia
17211:Peru
17149:Cuba
17045:Togo
16956:Mali
16664:List
15931:GACH
15415:Iota
15400:Zeta
15380:Beta
15212:(UK)
15206:(UK)
15126:Peru
15090:Fiji
15047:Cuba
14818:Iran
14786:Asia
14717:Chad
14529:V451
14524:V-01
14160:mRNA
13687:Apps
13428:Zoom
13191:Cuba
12752:U.S.
12747:U.K.
12658:Hajj
12223:U.S.
12117:USS
12036:Peru
11890:2023
11885:2022
11880:2021
11875:2020
11797:2022
11777:2020
11694:Niue
11664:Guam
11654:Fiji
11562:Utah
11474:Ohio
11322:Iowa
11297:Guam
11135:2021
11130:2020
10972:Saba
10822:Cuba
10709:2022
10704:2021
10699:2020
10323:2022
10318:2021
10313:2020
10010:2022
10005:2021
10000:2020
9924:2022
9919:2021
9914:2020
9897:2022
9892:2021
9887:2020
9870:2022
9865:2021
9860:2020
9828:2022
9823:2021
9733:2023
9611:Oman
9579:Iraq
9574:Iran
9511:West
9372:2022
9367:2021
9362:2020
9309:2023
9304:2022
9299:2021
9294:2020
9180:2022
9175:2021
9170:2020
9152:Laos
9133:2021
8839:2021
8538:East
8452:Asia
8438:Togo
8401:Mali
8357:2021
8273:Chad
7949:2024
7944:2023
7875:July
7863:June
7796:2022
7720:July
7708:June
7641:2021
7565:July
7553:June
7486:2020
7477:2019
6977:Zika
6937:MMRV
6785:Salk
6765:Mpox
6711:LAIV
6706:H5N1
6696:H1N1
6572:PPSV
6455:ACIP
6451:US:
6425:SAGE
6386:mRNA
6302:list
6208:xkcd
6148:2020
6085:PMID
6029:PMID
5977:2021
5947:2021
5914:2021
5877:PMID
5829:2022
5792:PMID
5733:PMID
5695:PMID
5675:ISBN
5638:2020
5611:2020
5563:PMID
5532:2020
5499:2020
5466:2020
5436:2020
5404:2020
5370:2020
5340:PMID
5283:PMID
5248:PMID
5238:ISBN
5207:PMID
5162:2021
5131:2020
5086:PMID
5050:PMID
5001:PMID
4960:PMID
4911:PMID
4864:2021
4833:2021
4802:2021
4766:2021
4732:2021
4698:2021
4663:PMID
4610:2021
4572:PMID
4527:2020
4514:Stat
4485:PMID
4423:PMID
4387:PMID
4338:PMID
4306:2020
4272:PMID
4223:PMID
4188:PMID
4170:ISSN
4132:help
4108:PMID
4098:ISBN
4067:PMID
4007:2021
3972:PMID
3921:PMID
3828:PMID
3769:PMID
3720:PMID
3672:2024
3646:PMID
3585:PMID
3547:2022
3516:2022
3486:2020
3455:2020
3420:PMID
3402:ISSN
3355:PMID
3316:2020
3282:PMID
3264:ISSN
3207:PMID
3164:PMID
3120:PMID
3112:ISSN
3073:2021
3047:2021
3013:2021
2979:2020
2966:Stat
2946:2021
2904:PMID
2869:PMID
2815:PMID
2764:PMID
2746:ISSN
2707:PMID
2699:ISSN
2655:PMID
2628:PMID
2579:PMID
2536:PMID
2493:PMID
2419:PMID
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2331:PMID
2272:PMID
2199:PMID
2152:2023
2127:2023
2101:2023
2076:2021
2049:PMID
1999:2020
1965:2021
1946:PMID
1896:2021
1862:2020
1836:2020
1800:2020
1763:PMID
1745:ISSN
1706:PMID
1696:ISBN
1666:2020
1620:PMID
1602:ISSN
1550:2020
1474:PMID
1425:PMID
1231:and
1116:and
1082:mRNA
1007:and
1001:mice
991:and
930:and
681:and
642:, a
630:The
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18332:RNA
16239:WHO
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14217:MVC
14069:DNA
13331:Aid
12385:NBA
8943:Goa
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7696:May
7541:May
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7071:BCG
6972:HIV
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6567:PCV
6520:Hib
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6075:doi
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5867:PMC
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5725:doi
5685:PMC
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5555:doi
5551:370
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5230:doi
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5040:PMC
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4991:doi
4987:278
4950:PMC
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4901:PMC
4891:doi
4754:CNN
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4057:PMC
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3962:PMC
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3911:PMC
3903:doi
3867:doi
3818:PMC
3808:doi
3759:PMC
3751:doi
3710:PMC
3702:doi
3698:169
3636:PMC
3626:doi
3575:doi
3474:FDA
3410:PMC
3394:doi
3347:doi
3335:589
3272:PMC
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