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Rhythms (1995âpresent), which holds an international symposium centered around chronobiology biannually. He served as the head of a Japan-U.S. joint project on
Biological Timing, where he was responsible for sending many Japanese scientists to the United States (1993â1995). While he was the president-elect of the Japanese Society of Chronobiology (2005 to 2010), he co-organized the biannual meetings of the European Biological Rhythms Society (EBRS) and held the first world congress of chronobiology in 2003 at Sapporo as the founding president of the World Federation for Societies of Chronobiology (2001â2011). He has tried to establish a forum among Chronobiologists in Asia as the council chief of the Asian Forum on Chronobiology (2015).
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Initially, his research revolved around understanding the photic and non-photic entrainment of circadian rhythms and raised hypotheses about the role of feeding in the entrainment of the circadian clock, as well as the ways in which endogenous rhythms can entrain to artificial bright light before
322:
an
English Journal of the Japanese Society of Sleep Research and the Asian Society of Sleep Research, and an associate member of the Science Council of Japan. Since 2016, Honma has also been a member of The Committee of ChronoHistory. Honma is the chairman of the Sapporo Symposium on Biological
417:
In 2017, Ken-Ichi and Sato Honma were part of the team at
Hokkaido University that discovered that voltage rhythms in the SCN were synchronized, a finding that became the basis for the theory that the SCN utilizes these synchronized rhythms in order to maintain tissue-wide rhythm.
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In 2016, he published an article that emphasized the role of physical activity, specifically in blind and elderly people, in the entrainment of circadian rhythms. The authors demonstrated that physical activity could also shift the plasma levels of melatonin.
406:-deficient mice. The authors showed that exposure to constant light by placing newborn mice in constant light for three weeks after they were born can partially restore rhythms in the SCN, even though the mice lose sleep-wake rhythms upon
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movement-person in Japan, advocating against the establishment of daylight-savings time in Japan by educating people on the detrimental health effects associated with the misalignment of the body's clock and the light-dark cycles
371:(PRC) to a single bright light pulse in human subjects living under isolation." He developed a model in animals for a sleep-wake cycle that is desynchronized from other circadian rhythms in the body such as the
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Honma S, Ikeda M, Abe H, Tanahashi Y, Namihira M, Honma K, Nomura M (September 1998). "Circadian oscillation of BMAL1, a partner of a mammalian clock gene Clock, in rat suprachiasmatic nucleus".
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in the SCN of rats. They found that BMAL1 expression was highest during the subjective night in rats and that rhythms of mRNA expression were found in other regions of the brain, like the
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neither establishes nor maintains circadian patterns in the body, but rather that it "refine the circadian firing rhythm to ensure noiseless communications with neurons outside the SCN."
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and Bmal1âwhich are central clock genes in mammalsâshows ultradian fluctuations and periods of approximately 3 hours. The research team also showed that these rhythms are most likely
280:. in Medicine in 1977 from the Hokkaido University School of Medicine. He worked as an assistant professor at Hokkaido University until 1978, when he left to perform research at the
440:, which are short-term rhythms with short-lasting periods. He has shown that in constant dark conditions, ultradian rhythms can be observed in the SCN, and that the expression of
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later focusing on uncovering the structure of the circadian clock. Earlier in his career, Honma made the discovery that body temperature, locomotor activity, and plasma levels of
315:
Honma was the former vice-president of the
Japanese Society of Sleep Research (2007â2021), the former council chair of the Japanese Society for Chronobiology (2005â2011).
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to be generated. Overall, the team concluded that ultradian rhythms had no correlation with the animal's physical activity rhythms, but further research is still needed.
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351:âall circadian processesâare likely coupled to one common internal oscillator in rats. However, his current research is centered around the
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Yamanaka Y, Honma KI, Hashimoto S, Takasu N, Miyazaki T, Honma S (2006-10-01). "Effects of physical exercise on human circadian rhythms".
332:
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Honma KI, Hiroshige T (November 1978). "Internal synchronization among several circadian rhythms in rats under constant light".
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Honma K, von Goetz C, Aschoff J (June 1983). "Effects of restricted daily feeding on freerunning circadian rhythms in rats".
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Honma has authored over 200 scholarly articles and has published several edited volumes in the field of chronobiology.
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Honma K, Honma S, Wada T (May 1987). "Entrainment of human circadian rhythms by artificial bright light cycles".
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In 2014, Honma and his colleagues published a paper that highlighted the effects of postnatal light on
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In 2020, Honma received the SRBR Directorâs Award for mentoring. The SRBR Award honors members of the
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He is the vice-president of the Asian
Society of Sleep Research (ASRS), the prior Editor-in-Chief of
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before beginning his research. His recent research efforts are centered around photic and non-photic
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1068:"Daylight Saving Time and Artificial Time Zones - A Battle Between Biological and Social Times"
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778:"Ontogeny of the circadian rhythm of plasma corticosterone in blind infantile rats"
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Honma serves as the chairman of the
Keiaikai Sapporo Hanazono Hospital, and is a
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Honma and his wife, Sato Honma, were able to detect circadian rhythms in
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and began working on experiments involving the human circadian clock in
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885:"Postnatal light overcomes genetic disturbance of circadian rhythms"
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967:"Synchronized voltage rhythms could maintain the body's clock"
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In 2019, Honma, with his collaborators, uncovered the role of
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of circadian clocks. He often collaborates with his wife,
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Roenneberg T, Winnebeck EC, Klerman EB (August 7, 2019).
429:(the central oscillator in mammals). They concluded that
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Honma has also been involved with recent research about
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Goh GH, Maloney SK, Mark PJ, Blache D (March 2019).
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296:. He first worked with Professor Wolfgang Wuttke in
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619:. Society for Research on Biological Rhythms. 2020.
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80:, potentially preventing the article from being
776:Hiroshige T, Honma K, Watanabe K (April 1982).
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1017:"Episodic Ultradian Events-Ultradian Rhythms"
586:"Ken-ichi Honma â Intercontinental Academia"
511:"Ken-ichi Honma â Intercontinental Academia"
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355:of circadian rhythms and understanding the
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53:Learn how and when to remove these messages
333:Society for Research on Biological Rhythms
206:(born in November 10, 1946) is a Japanese
100:reliable, independent, third-party sources
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993:"GABA neurons affect the circadian clock"
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191:Learn how and when to remove this message
173:Learn how and when to remove this message
118:Learn how and when to remove this message
617:Burroughs Welcome Fund Excellence Awards
94:by replacing them with more appropriate
964:Hokkaido University. (2017, April 24).
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77:too closely associated with the subject
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468:). Currently, Japan does not have any
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610:"SRBR Director's Award for Mentoring"
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590:intercontinental-academia.ubias.net
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743:The American Journal of Physiology
145:tone or style may not reflect the
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304:. In 1983, Honma was promoted to
244:mammalian suprachiasmatic nucleus
222:School of Medicine, he practiced
34:This article has multiple issues.
1134:21st-century Japanese biologists
926:10.1111/j.1479-8425.2006.00234.x
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155:guide to writing better articles
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75:may rely excessively on sources
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755:10.1152/ajpregu.1978.235.5.R243
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42:or discuss these issues on the
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320:Sleep and Biological Rhythms,
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669:10.1016/0031-9384(83)90256-1
272:In 1971, Honma received his
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459:Honma was a prominent anti-
425:in inhibiting cells in the
359:aspects of chronobiology.
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1149:Hokkaido University alumni
373:plasma levels of melatonin
782:The Journal of Physiology
657:Physiology & Behavior
335:for their contributions.
1085:10.3389/fphys.2019.00944
339:Scientific contributions
264:at Hokkaido University.
242:, on work involving the
218:. After graduating from
16:Japanese chronobiologist
1072:Frontiers in Physiology
427:suprachiasmatic nucleus
1034:10.3390/biology8010015
860:10.1006/bbrc.1998.9275
214:mechanisms underlying
384:in situ hybridization
274:Doctorate of Medicine
470:daylight saving time
382:gene expression via
369:phase response curve
282:Max-Planck Institute
268:Education and career
1144:People from Sapporo
889:Hokkaido University
367:Honma described "a
306:associate professor
294:postdoctoral fellow
230:, the structure of
224:clinical psychiatry
220:Hokkaido University
210:who researches the
712:10.1007/BF02143589
494:"Curriculum Vitae"
310:temporal isolation
262:professor emeritus
472:system in place.
438:ultradian rhythms
423:GABAergic neurons
327:Awards and honors
216:circadian rhythms
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149:used on Knowledge
147:encyclopedic tone
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891:. 2014-01-14
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90:Please help
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36:Please help
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1129:1946 births
854:(1): 83â7.
788:: 493â506.
700:Experientia
398:Later works
388:hippocampus
228:entrainment
1118:Categories
935:2115/45263
895:2021-05-01
641:2021-05-05
631:"çäœăȘășă ăźç 究"
595:2021-05-05
550:2021-05-05
520:2024-05-07
492:Honma KI.
476:References
466:zeitgebers
450:endogenous
392:cerebellum
240:Sato Honma
234:, and the
212:biological
92:improve it
82:verifiable
39:improve it
1027:(1): 15.
976:April 17,
944:1479-8425
570:April 20,
298:Göttingen
96:citations
45:talk page
1104:31447685
1053:30875767
952:73354269
728:40116177
685:20020358
390:and the
353:ontogeny
255:Hokkaido
246:(SCN).
236:ontogeny
163:May 2021
108:May 2021
1095:6692659
1078:: 944.
1044:6466064
1021:Biology
868:9735336
812:7108784
803:1251408
720:3582576
677:6611695
408:weaning
292:, as a
290:Germany
286:Andechs
251:Sapporo
86:neutral
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948:S2CID
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681:S2CID
613:(PDF)
497:(PDF)
380:Bmal1
1100:PMID
1049:PMID
978:2021
940:ISSN
864:PMID
808:PMID
759:PMID
716:PMID
673:PMID
635:ahmf
572:2021
544:ahmf
446:Per2
442:Per1
431:GABA
278:Ph.D
84:and
1090:PMC
1080:doi
1039:PMC
1029:doi
930:hdl
922:doi
856:doi
852:250
798:PMC
790:doi
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751:doi
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665:doi
284:in
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Text is available under the Creative Commons Attribution-ShareAlike License. Additional terms may apply.
