311:
Alzheimer's disease based on high dimensional, publicly available genetic and structural imaging data. Over 3,000 submissions were received and more than 500 scientists worldwide from more than 50 institutions and 10 countries participated in the challenge. This project, an invaluable first-of-its kind contribution, provided a snapshot of both the strengths and limitations in big data analytics of
Alzheimer's research.
31:
397:. The program has also provided training to indigenous medical professionals. As of 2019, the Rheumatic Relief team, which includes over 50 people each year, has screened more than 20,000 Samoan children for rheumatic heart disease and published significant findings from the first genome-wide association study of rheumatic heart disease susceptibility.
358:
and was a panelist for the 2015 National
Institutes of Health Summit on Alzheimer's disease Research. He served on the Scientific Program Committee for the Alzheimer's Association International Conference. He has had substantial funding from the National Institutes of Health National Institute on Aging (NIA) throughout his career.
357:
genetics using a variety of study designs and approaches. He has published more than 120 peer-reviewed papers including publications in the New
England Journal of Medicine, Nature, Nature Genetics, PNAS, and PLoS Genetics. He served as a Senior Editor for the journal Alzheimer's & Dementia
361:
In 2021, NIA awarded $ 14.6-million to a new project titled
Natives Engaged in Alzheimer's Research (NEAR) to expand treatment and research on Alzheimer’s disease and dementia in American Indian, Alaska Native, Native Hawaiian and Pacific Islander groups. Kauwe is one of three multi-principal
310:
Institute on Aging that have included international and multi-institutional collaborations. In 2014, he served as the scientific lead for the international
Alzheimer's disease Dream Challenge, a computational crowdsourced project to assess the capabilities of predicting cognitive outcomes in
404:
Kauwe has long maintained a relationship with Molokaʻi High School, his alma mater, including funded projects to provide scientific mentoring experiences and resources to teachers and students. He also speaks frequently to communities and academic organizations that serve underrepresented
253:, to John Sai Keong Kauwe Jr. and Rhonda Beth King Kauwe. He is of mixed ethnicity, including Native Hawaiian (kānaka maoli), Chinese, Portuguese, Māori, and Northern European ancestry. He was raised in Orem, Utah, and in Hawaii on the islands of Kauai, Oahu and Molokai, graduating from
388:
His recent work in linking the Utah
Population Database and Cache County Studies and developing reliable methods for pedigree identification has led to important findings about the relative risk for Alzheimer's disease and novel factors for its resilience.
400:
He also conducts research on the genetics of other human traits and diseases (height, biomarkers of inflammation) as well as work on de novo genome assembly and population genetics of marine fish, including bonefish, giant trevally, and bluefin trevally.
392:
Since 2013, he has served as the
Principal Investigator of Rheumatic Relief, a comprehensive program for public health education, screening, and genetics research designed to prevent and reduce suffering caused by rheumatic heart disease in
379:
Kauwe has mentored over 100 undergraduates in his research lab at BYU. His research efforts have been conducted with an intentional focus on outreach to populations that are underrepresented in biomedical science.
681:
654:
306:
Kauwe served at BYU as chair of the
Biology Department (2018 to 2019) and as dean of Graduate Studies (2019 to 2020). Kauwe has been the principal investigator on two multicenter grants from the
325:
Kauwe, the first native
Hawaiian to lead the university, was officially inaugurated as BYU–Hawaii's 11th president October 19, 2021. The inauguration was delayed for more than a year because of
1598:
1371:"Genome-wide Association Study of CSF Levels of 59 Alzheimer's Disease Candidate Proteins: Significant Associations With Proteins Involved in Amyloid Processing and Inflammation"
1422:"Atypical Chemokine Receptor ACKR2-V41A Has Decreased CCL2 Binding, Scavenging, and Activation, Supporting Sustained Inflammation and Increased Alzheimer's Disease Risk"
1789:
1607:
214:
1591:
466:
446:
776:
1584:
626:
1799:
826:
755:"Church Names Native Hawaiian as New President of Brigham Young University–Hawaii: John "Keoni" Kauwe and his wife, Monica, begin service on July 1"
226:
1749:
977:"Interaction Between Physical Activity and Genes Related to Neurotrophin Signaling in Late-Life Cognitive Performance: The Cache County Study"
1345:
369:, a Native Hawaiian led community organization dedicated to environmental sustainability, food security and resilience, and social justice.
1739:
329:
restrictions. Holland presided at the inauguration, with the other members of the executive committee of the Board of
Trustees,
1759:
1734:
926:
La, Cannon-Albright; Nl, Foster; K, Schliep; Jm, Farnham; Cc, Teerlink; H, Kaddas; J, Tschanz; C, Corcoran; Jsk, Kauwe (2019-04-09).
1024:
La, Cannon-Albright; S, Dintelman; T, Maness; J, Cerny; A, Thomas; S, Backus; Jm, Farnham; Cc, Teerlink; J, Contreras (2018-08-01).
491:
1754:
292:
229:(LDS Church) on April 4, 2024. Kauwe previously served as chair of the Department of Biology and as dean of Graduate Studies at
1769:
859:
754:
1075:"Sex Differences in Risk for Alzheimer's Disease Related to Neurotrophin Gene Polymorphisms: The Cache County Memory Study"
1254:"A Rapid Echocardiographic Screening Protocol for Rheumatic Heart Disease in Samoa: A High Prevalence of Advanced Disease"
705:
Gi, Allen; N, Amoroso; C, Anghel; V, Balagurusamy; Cj, Bare; D, Beaton; R, Bellotti; Da, Bennett; Kl, Boehme (June 2016).
1774:
1170:
218:
46:
1420:
Jdg, Murcia; A, Weinert; Cmt, Freitas; Dk, Arens; Mn, Ferrel; Jh, Grose; Pg, Ridge; E, Wilson; Jsk, Kauwe (2020-05-15).
288:
167:
1551:
1305:
Allen, Lori; Taylor, Fauatea; Kauwe, Adonica; Larsen, Tawny; Hippen, Ariel; Allen, Marvin; Kauwe, John (2017-02-02).
1195:
T, Parks; Mm, Mirabel; J, Kado; K, Auckland; J, Nowak; A, Rautanen; Aj, Mentzer; E, Marijon; X, Jouven (2017-05-11).
975:
Cl, Sanders; Gb, Rattinger; Ms, DeBerard; Ag, Hammond; H, Wengreen; Jsk, Kauwe; M, Buhusi; Jt, Tschanz (2019-09-06).
777:"John S.K. Kauwe III, first native Hawaiian to lead BYU–Hawaii, officially inaugurated as president by Elder Holland"
505:
1369:
Js, Kauwe; Mh, Bailey; Pg, Ridge; R, Perry; Me, Wadsworth; Kl, Hoyt; La, Staley; Cm, Karch; O, Harari (2014-10-23).
1307:"Using the Health Belief Model to evaluate Samoan caregiver perceptions for rheumatic heart disease follow-up care"
877:
Sm, Wright; Sl, Jensen; Kl, Cockriel; B, Davis; Jt, Tschanz; Rg, Munger; Cd, Corcoran; Jsk, Kauwe (December 2019).
1794:
1784:
1073:
J, Matyi; Jt, Tschanz; Gb, Rattinger; C, Sanders; Ek, Vernon; C, Corcoran; Jsk, Kauwe; M, Buhusi (2017-11-09).
413:
Kauwe married Monica Shana Mortensen in 2003 and they have five children. Kauwe is a direct descendant of
879:"Association Study of rs3846662 With Alzheimer's Disease in a Population-Based Cohort: The Cache County Study"
318:, chairman of the executive committee of the BYU–Hawaii Board of Trustees, announced that Kauwe would succeed
1744:
682:"Project Information - NIH RePORTER - NIH Research Portfolio Online Reporting Tools Expenditures and Results"
655:"Project Information - NIH RePORTER - NIH Research Portfolio Online Reporting Tools Expenditures and Results"
307:
1197:"Association Between a Common Immunoglobulin Heavy Chain Allele and Rheumatic Heart Disease Risk in Oceania"
1779:
376:, a biotechnology company focused on drug therapies for inflammatory disorders and neurological diseases.
1501:
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230:
154:
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81:
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354:
330:
238:
801:
1685:
1724:
1477:
1433:
1208:
1026:"Population Genealogy Resource Shows Evidence of Familial Clustering for Alzheimer Disease"
418:
291:, where he also completed a postdoctoral fellowship in Alzheimer's disease genetics at the
280:
265:
530:
258:
213:(born April 10, 1980) is an American geneticist and academic administrator serving as the
8:
894:
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878:
731:
706:
467:"Elder Holland shares why now is the time and season for a new president at BYU–Hawaii"
414:
315:
269:
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Kauwe joined the BYU faculty in 2009 and obtained the rank of full professor in 2018.
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221:(BYU–Hawaii), a position he has held since July 1, 2020. He was also sustained as an
162:
1346:"BYU genetic researchers solve a giant mystery: How Shawn Bradley got to be so tall"
1330:
1146:
707:"Crowdsourced Estimation of Cognitive Decline and Resilience in Alzheimer's Disease"
602:
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718:
422:
1322:
492:"New Area Seventies Sustained at April 2024 General Conference Leadership Session"
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334:
554:
1445:
1252:
M, Allen; J, Allen; T, Naseri; R, Gardner; D, Tolley; L, Allen (October 2017).
1079:
The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
981:
The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
722:
1478:"NSF Award Search: Award#1626609 - MRI:Acquisition of an PacBio Sequel System"
1269:
447:"BYU administrator named as BYU-Hawaii's new president, replacing John Tanner"
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populations, including recent engagements in Samoa, Hawaii, and Alaska.
272:
in population genetics (2003) at BYU. From 1999 to 2001, he served as a
1556:
Maui Now | Hawaii News | Molokaʻi High to Dedicate New Science Building
762:
928:"Relative Risk for Alzheimer Disease Based on Complete Family History"
627:"Get to know BYU–Hawaii's new president — a native son of the islands"
55:
191:
860:""Here's how Halia Therapeutics aims to curb Alzheimer's—and more""
326:
1606:
277:
30:
1502:"Collaboration Boosts Science Education | The Molokai Dispatch"
1171:"How a BYU program is helping kids in Samoa stay heart healthy"
827:""Combating dementia in Native, Pacific Islander communities""
237:, Utah. He is a researcher who specializes in the genetics of
580:"MHS Alum Named BYU-HI President | the Molokai Dispatch"
394:
372:
Kauwe is co-founder and Scientific Advisory Board chair of
1552:"Maui Now: Molokaʻi High to Dedicate New Science Building"
287:
in evolution, ecology and population biology in 2007 from
284:
171:
747:
1311:
International Journal of Health Promotion and Education
506:"New Department Chairs in the College of Life Sciences"
353:
Kauwe's professional focus has been primarily studying
1527:"New Science Facility Unveiled | The Molokai Dispatch"
1304:
373:
365:
Kauwe currently serves on the Board of Directors of
257:(formerly Molokai High and Intermediate School) in
440:
438:
1716:
1344:Hollingshead, Media Contact: Todd (2018-09-06).
322:as the institution's president on July 1, 2020.
249:The oldest of seven children, Kauwe was born in
435:
227:the Church of Jesus Christ of Latter-day Saints
1790:Presidents of Brigham Young University–Hawaii
1609:Presidents of Brigham Young University–Hawaii
1592:
182:Geneticist, academic administrator, professor
1343:
529:Ipson, Media Contact: Natalie (2019-05-14).
417:, who was among the first Native Hawaiians
244:
1599:
1585:
824:
29:
1800:Washington University in St. Louis alumni
1453:
1419:
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1228:
1098:
1049:
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902:
730:
16:American university president (born 1980)
974:
293:Washington University School of Medicine
1368:
925:
876:
1717:
1072:
857:
1750:American Mormon missionaries in Japan
1580:
1194:
1023:
704:
676:
674:
649:
647:
528:
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1251:
895:10.1016/j.neurobiolaging.2019.03.004
825:McLaughlin, Susan (August 9, 2021).
597:
595:
593:
591:
589:
13:
671:
644:
531:"New dean of BYU Graduate Studies"
289:Washington University in St. Louis
168:Washington University in St. Louis
14:
1811:
1572:
586:
1760:Brigham Young University faculty
1735:21st-century American biologists
858:Oliver, Jeremie (May 20, 2022).
408:
383:
276:for the LDS Church in the Japan
268:in molecular biology (1999) and
211:John "Keoni" Sai Keong Kauwe III
23:John "Keoni" Sai Keong Kauwe III
1755:Brigham Young University alumni
1740:Alzheimer's disease researchers
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219:Brigham Young University–Hawaii
132:
47:Brigham Young University–Hawaii
619:
572:
547:
522:
498:
484:
459:
362:investigators on the project.
1:
1770:Latter Day Saints from Hawaii
1323:10.1080/14635240.2016.1250661
308:National Institutes of Health
1388:10.1371/journal.pgen.1004758
1042:10.1212/NXG.0000000000000249
944:10.1212/WNL.0000000000007231
7:
445:Walch, Tad (May 12, 2020).
348:
10:
1816:
1775:Native Hawaiian scientists
1446:10.1038/s41598-020-64755-1
802:"kauwe j - Search Results"
723:10.1016/j.jalz.2016.02.006
711:Alzheimer's & Dementia
428:
1616:
1270:10.1017/S1047951117000907
343:Church Educational System
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21:
1147:"Saving Hearts in Samoa"
245:Early life and education
231:Brigham Young University
155:Brigham Young University
1258:Cardiology in the Young
686:projectreporter.nih.gov
659:projectreporter.nih.gov
421:into the LDS Church by
333:, Paul V. Johnson, and
1795:Scientists from Hawaii
1785:People from Orem, Utah
1531:themolokaidispatch.com
1506:themolokaidispatch.com
341:, commissioner of the
331:D. Todd Christofferson
45:11th President of
1201:Nature Communications
1091:10.1093/gerona/glx092
993:10.1093/gerona/glz200
883:Neurobiology of Aging
555:"John S.K. Kauwe III"
1745:American geneticists
425:in the early 1850s.
255:Molokaʻi High School
35:John S. K. Kauwe III
1780:People from Molokai
1438:2020NatSR..10.8019M
1221:10.1038/ncomms14946
1213:2017NatCo...814946P
1030:Neurology. Genetics
938:(15): e1745–e1753.
355:Alzheimer's disease
239:Alzheimer's disease
1426:Scientific Reports
1127:Biology Department
1123:"Rheumatic Relief"
374:Halia Therapeutics
345:, also attending.
316:Jeffrey R. Holland
261:, Hawaii in 1996.
1765:Human geneticists
1712:
1711:
1085:(12): 1607–1613.
889:: 242.e1–242.e6.
314:On May 12, 2020,
266:bachelor's degree
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1381:(10): e1004758.
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339:Clark G. Gilbert
283:. He received a
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494:. 4 April 2024.
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335:Jean B. Bingham
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270:master's degree
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135: 2003)
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125:Monica S. Kauwe
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1573:External links
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1317:(3): 148–157.
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582:. 22 May 2020.
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