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are strongly associated with long-term deterioration and worsening of the patient's condition. Most cases of hemorrhagic transformation, including the majority of petechial hemorrhages, are asymptomatic and do not cause noticeable symptoms.
110:
HT can lead to further damage to the brain tissue and worsen the outcome of the initial stroke. The risk of HT increases with the severity and duration of the initial stroke, as well as with certain medical conditions such as
418:"Treatment and Outcome of Hemorrhagic Transformation After Intravenous Alteplase in Acute Ischemic Stroke: A Scientific Statement for Healthcare Professionals From the American Heart Association/American Stroke Association"
522:
Stone JA, Willey JZ, Keyrouz S, Butera J, McTaggart RA, Cutting S, et al. (January 2017). "Therapies for
Hemorrhagic Transformation in Acute Ischemic Stroke".
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In the medical literature, various criteria have been used to establish whether a hemorrhagic infarction is symptomatic or not. Studies have shown that only
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Signs and symptoms can vary depending on the severity and location of the bleeding within the brain tissue.
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369:"Predicting Hemorrhagic Transformation of Acute Ischemic Stroke: Prospective Validation of the HeRS Score"
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In majority seen within 4 days of initial stroke. In patients treated with thrombolysis - within 24 hours.
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Yaghi S, Willey JZ, Cucchiara B, Goldstein JN, Gonzales NR, Khatri P, et al. (December 2017).
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Marsh EB, Llinas RH, Schneider AL, Hillis AE, Lawrence E, Dziedzic P, Gottesman RF (January 2016).
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Spronk E, Sykes G, Falcione S, Munsterman D, Joy T, Kamtchum-Tatuene J, Jickling GC (2021).
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Effective treatment is complex and may involve medications to control bleeding (reversing
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470:"Hemorrhagic Transformation After Ischemic Stroke: Mechanisms and Management"
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of brain tissue that has been affected by the stroke and can take two forms:
318:"Hemorrhagic Transformation in Ischemic Stroke and the Role of Inflammation"
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of blood from the peripheral circulation across a disrupted
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Hemorrhagic transformation is a process which involves the
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270:The NINDS t-PA Stroke Study Group (November 1997).
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246:"Hemorrhagic transformation of ischemic infarct"
84:is a medical complication that can occur in the
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524:Current Treatment Options in Neurology
221:Around 10-15% of patients with acute
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565:Unnithan AK, Das J, Mehta P (2022).
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164:Some common symptoms might include:
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213:(BBB) and into the brain tissue.
468:Hong JM, Kim DS, Kim M (2021).
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78:Hemorrhagic transformation (HT)
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435:10.1161/STR.0000000000000152
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385:10.1097/MD.0000000000002430
250:Radiology Reference Article
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33:Hemorrhagic transformation
536:10.1007/s11940-017-0438-5
487:10.3389/fneur.2021.703258
335:10.3389/fneur.2021.661955
289:10.1161/01.str.28.11.2109
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604:Complications of stroke
474:Frontiers in Neurology
322:Frontiers in Neurology
105:parenchymal hemorrhage
82:hemorrhagic conversion
18:Hemorrhagic conversion
158:parenchymal hematomas
567:"Hemorrhagic Stroke"
179:Weakness or numbness
101:petechial hemorrhage
211:blood-brain barrier
113:high blood pressure
88:following an acute
149:Signs and symptoms
121:clotting disorders
428:(12): e343–e361.
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16:(Redirected from
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173:Changes in
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571:StatPearls
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256:2023-02-28
229:References
136:alteplase
134:(such as
44:Neurology
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598:Category
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506:34917010
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373:Medicine
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196:problems
183:Seizures
169:Headache
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194:Vision
188:Speech
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548:S2CID
448:S2CID
86:brain
58:Types
575:PMID
540:PMID
502:PMID
440:PMID
399:PMID
350:PMID
294:PMID
127:and
103:and
532:doi
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